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vllm-0a33d04154fc4ef5be191f43293e47f1 | 19134000 | {
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"content": "{\"REASONING\": ['The context describes an experiment where PTEN inhibition using bpV(phen) was evaluated for its ability to prevent acute lung injury induced by oleic acid in mice.', 'The results showed that PTEN inhibition increased phospho-Akt and ERK levels, reduced protein content, lactate dehydrogenase, tumor necrosis factor-alpha, and chemokines in bronchoalveolar lavage fluid, and decreased the incidence of alveolar lesions and TUNEL-positive cells.', 'The context explicitly states that PTEN suppression maintained pulmonary function and that no injury was observed in the bpV(phen) treatment groups.', 'The answer accurately reflects the findings in the context, indicating that inhibition of PTEN protected mice against oleic acid-induced acute lung injury.'], \"SCORE\": PASS}"
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vllm-c25c41fca9b74a1c9db6fba325805d14 | 23897505 | {
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"model": "llama-3-70b",
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"content": "{\"REASONING\": ['The context provides a comparison between adductor canal CPNB and femoral CPNB in terms of ambulation distance, pain scores, daily opioid consumption, and hospital length of stay after TKA.', 'The study found that ambulation distances were significantly higher in the adductor canal group compared to the femoral group on both Postoperative Day 1 and 2.', 'Adjusted linear regression confirmed the association between adductor canal catheter use and increased ambulation distance on both days.', 'Pain scores, daily opioid consumption, and hospital length of stay were similar between the two groups, indicating no reduction in analgesia.', 'The answer accurately reflects the findings from the context, stating that adductor canal CPNB may promote greater early postoperative ambulation compared to femoral CPNB without a reduction in analgesia.'], \"SCORE\": PASS}"
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vllm-c727105b2e9d45a08ddc31228062c6c5 | 16442035 | {
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"model": "llama-3-70b",
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"content": "{\"REASONING\": ['The CONTEXT describes a study that evaluated the infection rates associated with the use of sterile versus nonsterile gloves during Mohs micrographic surgery.', 'The study included 1,810 patients and found no statistical difference in infection rates based on the type of gloves used (sterile or nonsterile).', 'The ANSWER states that the study supports the use of clean, nonsterile gloves as safe and effective, which aligns with the findings in the CONTEXT.', 'The ANSWER also mentions a significant cost savings, which is a reasonable inference given the equivalence in infection rates and the likely lower cost of nonsterile gloves.'], \"SCORE\": PASS}"
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vllm-353ee5bc63254a4fb5864b2d65dee23a | 12048081 | {
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"model": "llama-3-70b",
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"content": "{\"REASONING\": ['The CONTEXT provides information about a study comparing fast track extubation and non-fast track extubation protocols after coronary artery bypass graft surgery with cardiopulmonary bypass.', 'The study included 76 patients in the fast track extubation group and 188 patients in the non-fast track extubation group.', 'The CONTEXT states that morbidity and mortality were similar in both groups, indicating that the complication rates were not significantly different between the two groups.', 'The ANSWER correctly reflects the findings of the study by stating that early extubation does not increase complication rates.'], \"SCORE\": PASS}"
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"total_tokens": 737,
"completion_tokens": 129
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vllm-8dcd7415f0c149f0a0869472c76c969e | 22648653 | {
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"model": "llama-3-70b",
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{
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"message": {
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"content": "{\"REASONING\": ['The context provides detailed information about a study examining the association between serum 25(OH)D levels and all-cause mortality.', 'The study found that subjects who died had significantly lower serum 25(OH)D levels compared to those who were alive at the end of the follow-up period.', 'After adjusting for various factors, the hazard ratio (HR) for all-cause mortality was higher for lower serum 25(OH)D quartiles compared to the highest quartile.', 'The fully adjusted HR for the lowest quartile was 1.85, and for the second quartile was 1.25, indicating an inverse association between serum 25(OH)D levels and all-cause mortality.', 'The answer correctly states that all-cause mortality is inversely associated with serum 25(OH)D levels at levels less than 50 nmol/liter, which aligns with the findings presented in the context.'], \"SCORE\": PASS}"
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vllm-d39cf29dd93a432697bfa65d29d7d57b | 14600003 | {
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"model": "llama-3-70b",
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"message": {
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"content": "{\"REASONING\": ['The CONTEXT discusses the predictive validity of the MOBLI index for mortality based on data from the EPESE study.', 'The CONTEXT mentions that the MOBLI score is associated with subsequent mortality over 4 years and has a predictive value similar to self-reported mobility disability.', 'The ANSWER states that the MOBLI index has predictive validity as a measure of mobility limitation in older populations, which aligns with the findings in the CONTEXT.', 'The ANSWER also mentions the empirical basis, face validity, and responsiveness to change, which are all supported by the CONTEXT.'], \"SCORE\": PASS}"
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vllm-72a7946f5f9a45568f7a5fda0ce4fe46 | 20472097 | {
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"model": "llama-3-70b",
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"message": {
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"content": "{\"REASONING\": ['The CONTEXT states that abdominal pain was present in 90% of patients with gastroparesis, indicating it is a very common symptom.', 'The CONTEXT also mentions that nausea was present in 96% of patients, which is slightly more frequent than abdominal pain.', 'The ANSWER claims that abdominal pain is comparable in frequency to nausea and vomiting, which is not entirely accurate as nausea is slightly more prevalent.', 'The CONTEXT does confirm that abdominal pain severity does not correlate with gastric emptying (GE) but has a moderate correlation with quality of life, which is correctly reflected in the ANSWER.'], \"SCORE\": FAIL}"
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"total_tokens": 726,
"completion_tokens": 133
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vllm-50dc9a87c0dd488f98987fcc21fc4a6a | 25244167 | {
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"object": "chat.completion",
"created": 1719619523,
"model": "llama-3-70b",
"choices": [
{
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"message": {
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"content": "{\"REASONING\": ['The context describes a case where a patient was referred to the dermatology department for cosmetic concerns and was found to have facial angiofibromas and a truncal collagenoma.', 'These cutaneous findings led to the suspicion of a genodermatosis, and subsequent genetic testing confirmed the diagnosis of multiple endocrine neoplasia type-1 (MEN-1).', 'The answer states that incidental angiofibromas can prompt a diagnosis of MEN-1, which aligns with the context where the diagnosis was suspected based on the cutaneous findings.', \"The answer also highlights the importance of dermatologists being aware of subtle skin findings that may indicate rare disorders, which is consistent with the context where the dermatologists played a crucial role in suspecting and diagnosing MEN-1.\"], \"SCORE\": PASS}"
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"usage": {
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"completion_tokens": 175
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vllm-dbba4eef48d04c1ea14f771df1cd8bc0 | 18780322 | {
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"model": "llama-3-70b",
"choices": [
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"message": {
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"content": "{\"REASONING\": ['The context provides detailed information about a study examining the disagreement between physicians and patients regarding performance status (PS) and its association with survival outcomes.', 'The study found that there is a significant disagreement between physicians and patients in assessing PS, with physicians tend to rate patients better than patients rate themselves.', 'The context explicitly states that disagreement between patients and their physicians is associated with an increased risk of death, providing specific hazard ratios and p-values for KPS and nutrition scores.', 'The answer accurately reflects the findings from the context, stating that disagreement is associated with an increased risk of death in patients with advanced malignancies.', \"The answer also mentions the limitations of physician-only assessed PS, which is a reasonable inference based on the context's findings of frequent disagreements and the prognostic importance of accurate PS assessment.\"], \"SCORE\": PASS}"
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vllm-534d331d76754285a7607163d8bfb691 | 24668496 | {
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"model": "llama-3-70b",
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{
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"message": {
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"content": "{\"REASONING\": ['The CONTEXT describes a study on the pharmacokinetics and local tissue responses of recombinant human HGF administered to rat vocal folds, not human vocal folds.', 'The study involved Sprague-Dawley rats, not humans, and investigated the concentration of HGF in larynges and blood, as well as local tissue responses.', 'The ANSWER suggests that the results contribute to the safety and pharmacokinetic management of future clinical trials using HGF administered to human vocal folds, which is not supported by the CONTEXT.', 'The CONTEXT does not provide evidence or results specific to human clinical trials or the administration of HGF to human vocal folds.'], \"SCORE\": FAIL}"
},
"logprobs": null,
"finish_reason": "stop",
"stop_reason": null
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],
"usage": {
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"total_tokens": 667,
"completion_tokens": 144
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vllm-9bfcad9466b04245837385287ac8eb45 | 16556668 | {
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"created": 1719619524,
"model": "llama-3-70b",
"choices": [
{
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"message": {
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"content": "{\"REASONING\": ['The CONTEXT provides detailed information on the frequency of genetic aberrations in primary and secondary intestinal MALT lymphomas.', 'It mentions a significant difference in the frequency of t(11;18)(q21;q21) between secondary MALT lymphomas and primary intestinal and gastric MALT lymphomas.', 'The CONTEXT also states that primary intestinal MALT lymphoma had a significantly higher frequency of trisomies 3 or 18 compared to secondary intestinal MALT lymphomas and localized gastric MALT lymphomas.', 'The ANSWER accurately reflects these findings by stating that the genetic profile of primary intestinal MALT lymphomas is different from that of secondary intestinal or local gastric MALT lymphomas.', 'The ANSWER also correctly highlights the high prevalence of trisomy 3 or 18 in primary intestinal lymphoma, which is supported by the CONTEXT.'], \"SCORE\": PASS}"
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"finish_reason": "stop",
"stop_reason": null
}
],
"usage": {
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vllm-e5bc889fa4a14c0596adb7e609ac1403 | 26452389 | {
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"object": "chat.completion",
"created": 1719619524,
"model": "llama-3-70b",
"choices": [
{
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"message": {
"role": "assistant",
"content": "{\"REASONING\": ['The context provides evidence that rapid increase and variability in BMI during childhood are associated with increased adult BMI and waist circumference.', 'The study found that one standard deviation increase in the rate of change in BMI during childhood was associated with a significant increase in adult BMI and waist circumference, independently of childhood mean BMI.', 'Similarly, one standard deviation increase in the variability of BMI during childhood (measured by RSD) was also associated with significant increases in adult BMI and waist circumference.', 'The odds ratio for adult obesity increased progressively from the lowest to the highest quartile of BMI rate of change or RSD during childhood, indicating a trend.', 'Therefore, the answer accurately reflects the findings presented in the context, supporting the idea that rapid increase and greater variability in BMI during childhood are independent risk factors for adult obesity.'], \"SCORE\": PASS}"
},
"logprobs": null,
"finish_reason": "stop",
"stop_reason": null
}
],
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"completion_tokens": 174
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vllm-a501311bba454ebea2aa57254e90ca6a | 16351738 | {
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"model": "llama-3-70b",
"choices": [
{
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"message": {
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"content": "{\"REASONING\": ['The CONTEXT discusses the application of Hidden Markov Models (HMM) to predict membrane protein topology and mentions various decoding algorithms, including the introduction of a new algorithm called posterior-Viterbi (PV).', 'The CONTEXT does not specifically mention the performance of the PV algorithm on all-beta membrane proteins or compare its performance to other algorithms for this specific type of protein.', 'The ANSWER claims that PV decoding performs better than other algorithms when tested on the problem of predicting the topology of beta-barrel membrane proteins, which is a specific type of all-beta membrane proteins.', 'The CONTEXT does not provide evidence or results that directly support the claim made in the ANSWER about the performance of PV decoding on all-beta membrane proteins.', 'Therefore, the ANSWER is not faithful to the CONTEXT because it makes a specific claim that is not supported by the provided information.'], \"SCORE\": FAIL}"
},
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vllm-f8cb2d4991a34e66adc1acdfb25fb87f | 21113014 | {
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"created": 1719619524,
"model": "llama-3-70b",
"choices": [
{
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"message": {
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"content": "{\"REASONING\": ['The CONTEXT describes the inversa type of recessive dystrophic epidermolysis bullosa (RDEB-I) and mentions that it is associated with specific recessive arginine and glycine substitutions in the triple helix domain of type VII collagen.', 'The ANSWER states that the inversa type of RDEB is caused by specific arginine and glycine substitutions in type VII collagen, which aligns with the information provided in the CONTEXT.', \"The ANSWER also notes that the reason why these specific substitutions cause the inversa distribution remains unknown, which is consistent with the CONTEXT's mention that the cause of this specific distribution is unknown.\", 'The CONTEXT discusses the study of genotype-phenotype correlations and mentions that it was not possible to identify clear differences in the location and nature of substituting amino acids between these mutations and missense mutations causing other RDEB phenotypes, which is reflected in the ANSWER.'], \"SCORE\": PASS}"
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"stop_reason": null
}
],
"usage": {
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"total_tokens": 767,
"completion_tokens": 200
}
} | null |
vllm-6f3a4153a1d94f918b1cf9e9b20b40bd | 17762289 | {
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"created": 1719619524,
"model": "llama-3-70b",
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{
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"message": {
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"content": "{\"REASONING\": ['The context provides detailed information about a study that measured elastin content in nondegenerate and degenerate human intervertebral discs.', 'The study found that elastin content increases significantly with degeneration in all locations (OAF, IAF, NP), with the highest increase in the IAF.', 'The context mentions that elastin content correlates with degenerative grade and age at each site.', 'The answer states that elastin content correlates with human disc degeneration and provides additional information about the potential functional role of elastin in restoring lamellar structure under radial loads.', 'The answer is consistent with the findings and data provided in the context.'], \"SCORE\": PASS}"
},
"logprobs": null,
"finish_reason": "stop",
"stop_reason": null
}
],
"usage": {
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"total_tokens": 783,
"completion_tokens": 142
}
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vllm-8ef8269d6b984298ade7fe0a2d1c4c65 | 26103960 | {
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"model": "llama-3-70b",
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{
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"message": {
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"content": "{\"REASONING\": ['The CONTEXT describes a study that analyzed the association between serum EndoCab levels and linear growth in rural Malawian children aged 2-5 years.', 'The study found no correlation between ln EndoCab concentrations and height-for-age z scores (HAZ) at the time of measurement or with the change in HAZ over the subsequent 3 months.', 'Additionally, the study found no association between EndoCab concentration and %lactulose excretion or the lactulose:mannitol ratio, which are measures of intestinal permeability.', 'The subgroup analysis also did not reveal any significant association between EndoCab and recent growth.', 'Therefore, the ANSWER accurately reflects the findings from the CONTEXT, stating that EndoCab titers were not correlated with measurements of growth or intestinal permeability in rural pre-school aged Malawian children.'], \"SCORE\": PASS}"
},
"logprobs": null,
"finish_reason": "stop",
"stop_reason": null
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"usage": {
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}
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vllm-ca879faf6be940b09f9abbed9671137b | 18451223 | {
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"created": 1719619524,
"model": "llama-3-70b",
"choices": [
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"message": {
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"content": "{\"REASONING\": ['The context describes a study that investigated the role of isolated tumor cells (ITCs) and vascular endothelial growth factor receptor-1 (VEGFR-1) in gastric cancer metastasis.', 'The study found that ITCs were present in both peripheral blood and bone marrow, even in early stages of gastric cancer.', 'The frequency of ITCs in bone marrow was significantly associated with the stage of disease.', 'The study also found that gastric cancer metastasized when ITCs were observed in the presence of VEGFR-1.', 'In patients who were ITC negative and had low VEGFR-1 expression, no metastases were observed.', 'The answer accurately reflects these findings by stating that ITCs circulate even in early stages and that elevated VEGFR-1 expression facilitates hematogenous metastases.'], \"SCORE\": PASS}"
},
"logprobs": null,
"finish_reason": "stop",
"stop_reason": null
}
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"completion_tokens": 182
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vllm-10265d14365e484480d341935f2c3b04 | 22483414 | {
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"object": "chat.completion",
"created": 1719619524,
"model": "llama-3-70b",
"choices": [
{
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"message": {
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"content": "{\"REASONING\": ['The context describes a study that investigates the relationship between H. pylori status and the dynamics of the ghrelin system, including GOAT expression.', 'The study found that plasma acyl-ghrelin and desacyl-ghrelin concentrations were significantly lower in H. pylori positive participants compared to H. pylori negative controls.', 'The study also found that ghrelin and GOAT mRNA levels in the gastric mucosa were significantly lower in H. pylori positive participants.', 'After H. pylori eradication, plasma acyl-ghrelin levels tended to increase, and plasma desacyl-ghrelin levels were significantly reduced. Gastric ghrelin mRNA expression increased significantly, but gastric GOAT mRNA expression tended to increase but was not significantly altered.', 'These findings suggest that H. pylori status does influence plasma ghrelin isoforms and gastric GOAT expression, supporting the answer.'], \"SCORE\": PASS}"
},
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vllm-d74cdd46aa574f0c9a67c60cdfcc2f14 | 23994111 | {
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"object": "chat.completion",
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"model": "llama-3-70b",
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{
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"message": {
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"content": "{\"REASONING\": ['The CONTEXT provides data on the use of dried blood spots (DBS) for Western blot confirmation at non-clinical HIV rapid testing sites.', 'The CONTEXT mentions that 85.1% of DBS specimens were positive for Western blot, compared to 78.6% of venous blood specimens.', 'The CONTEXT also states that the frequency of unsatisfactory specimens did not differ significantly between DBS (1.4%) and venous blood (3.4%).', 'The ANSWER correctly interprets that the percentage of positive Western blot results was significantly greater for DBS specimens and that the frequency of unsatisfactory specimens did not differ significantly.', 'Therefore, the ANSWER is faithful to the CONTEXT as it accurately reflects the data and conclusions presented.'], \"SCORE\": PASS}"
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vllm-cbb69b5d48784741bf266839670a6dea | 25246784 | {
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"object": "chat.completion",
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"model": "llama-3-70b",
"choices": [
{
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"message": {
"role": "assistant",
"content": "{\"REASONING\": ['The context indicates that nutritional depletion and muscle atrophy are related to systemic inflammation, as evidenced by the correlation between BMI and serum CRP levels.', 'The context also mentions that there were no differences in airway inflammation and bacterial colonization in patients with and without nutritional depletion, suggesting that airway inflammation is not a key driver of muscle atrophy.', 'The answer correctly states that nutritional depletion and progressive muscle atrophy are not related to airway inflammation or bacterial colonization, which aligns with the context.', \"The answer also mentions that overspill of pulmonary inflammation is not a key driver of muscle atrophy in COPD, which is consistent with the context's findings on the lack of relationship between airway inflammation and nutritional depletion.\"], \"SCORE\": PASS}"
},
"logprobs": null,
"finish_reason": "stop",
"stop_reason": null
}
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"usage": {
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"total_tokens": 762,
"completion_tokens": 158
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vllm-f04bd7b43b8543e5a02bc270d1122eb3 | 11450018 | {
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"model": "llama-3-70b",
"choices": [
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"message": {
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"content": "{\"REASONING\": ['The context describes that spreading depression (SD) induces cell swelling, but it does not necessarily lead to permanent cell swelling under penumbra conditions.', 'The context specifies that cell swelling persists as long as the flow remains critically reduced, but it does not confirm that the swelling is permanent.', 'The context mentions that 15 minutes of SD-induced cell swelling was tolerated without permanent damage, suggesting that the swelling may not always be permanent.', 'The answer incorrectly generalizes that SD always induces permanent cell swelling under penumbra conditions, which is not supported by the context.'], \"SCORE\": FAIL}"
},
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"completion_tokens": 126
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vllm-a5cae7f3e13a4ebeb8d9ea665e4ad4c5 | 27433903 | {
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"content": "{\"REASONING\": ['The context describes a study where paraincisional subcutaneous infusion of ropivacaine was used after open abdominal vascular surgery.', 'The study compared a control group receiving standard postoperative pain management with a group treated with paraincisional continuous local analgesia using ropivacaine.', 'The results showed that patients in the ropivacaine group received significantly less morphine while reporting similar pain intensity as the control group.', 'The length of intensive care unit (ICU) stay was significantly shorter in the ropivacaine group.', 'The answer summarizes these findings, stating that continuous paraincisional subcutaneous infusion of ropivacaine is a feasible method of postoperative analgesia that allows sustained pain relief with significant reduction of opiate requirement and faster recovery after surgery.'], \"SCORE\": PASS}"
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"content": "{\"REASONING\": ['The context states that miR-26a and miR-138 are significantly down-regulated in prostate cancer and are direct regulators of EZH2, an oncogene in prostate cancer.', 'The study evaluated the influence of miR-26a and miR-138 on EZH2 and cellular function, including the impact on the cell cycle regulating network in PCa cells.', 'Both miRNAs inhibited short- and long-term proliferation of PCa cells but showed no effect on viability and apoptosis.', 'In PC-3 cells, miR-26a and miR-138 caused a significant surplus of cells in the G0/G1 phase, thus blocking the G1/S-phase transition.', 'The context also mentions that miR-26a and miR-138 targeted and suppressed specific cell cycle regulators such as CCNE1, CCNE2, CDK6, CCND1, CCND3, and CDK6.', 'The answer correctly summarizes that miR-26a and miR-138 block the G1/S-phase transition by targeting the cell cycle regulating network in prostate cancer cells, independent of EZH2.'], \"SCORE\": PASS}"
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"content": "{\"REASONING\": ['The context mentions that little research has been conducted on the implications of Sirt1 in neuropathic pain, indicating a lack of existing evidence.', 'The study aimed to investigate the expressions of spinal Sirt1 and acetyl-histone H3 in a rat model of chronic constriction injury.', 'The context provides data showing that Sirt1 expression decreased and acetyl-histone H3 increased in the spinal cord following CCI surgery.', 'The administration of resveratrol, an activator of Sirt1, attenuated pain and increased Sirt1 expression while decreasing acetyl-histone H3.', 'The answer claims that the data provide new evidence for the contribution of spinal Sirt1 to neuropathic pain and that resveratrol’s antinociceptive effects are mediated through the activation of spinal Sirt1, which aligns with the findings in the context.'], \"SCORE\": PASS}"
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vllm-74633a7baedf4b5599c124d6014eef25 | 27141151 | {
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"content": "{\"REASONING\": ['The context describes a study that investigated the effect of different surface treatments on the shear bond strength (SBS) of resin cement to zirconia.', 'The study included a control group and groups treated with air abrasion, a universal primer, and a fractional CO2 laser with different settings.', 'The results showed a statistically significant difference in SBS among the groups, with the highest SBS values observed in the groups treated with the fractional CO2 laser.', 'The groups treated with the fractional CO2 laser had SBS values of 28.1 MPa and 27.4 MPa, which were significantly higher than the control group (9.4 MPa) and the group treated with the universal primer (22.8 MPa).', 'The answer states that the application of a fractional CO2 laser can improve the bond strength of resin cement to zirconia ceramic, which is consistent with the findings in the context.'], \"SCORE\": PASS}"
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vllm-fe4bac5c9ec6496e9ff5b7f85e2cfbfc | 24066107 | {
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"content": "{\"REASONING\": ['The context describes a study investigating the modulation of NOP and PNoc by inflammatory mediators in human whole blood cultures.', 'It mentions that LPS significantly suppressed both NOP and PNoc expression compared to baseline measures.', 'The context also states that incubation with TNF-α, IL-1β, IL-10, or IFN-γ decreased NOP mRNA levels to varying extents, while PNoc mRNA expression was decreased only by IL-10.', 'The answer accurately reflects these findings by stating that LPS and cytokines suppress mainly NOP and, in part, PNoc mRNA expression.', \"The answer also suggests a negative feedback loop, which is consistent with the context's mention of the upregulation of cytokines by PNoc.\"], \"SCORE\": PASS}"
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vllm-75f0ca3b014147f4af3a3aba21e99c1e | 22298725 | {
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"content": "{\"REASONING\": ['The QUESTION asks whether patients and their families have a say in evidence-based hospital design.', 'The CONTEXT discusses the evolution of evidence-based design in response to deficiencies in the healthcare system and mentions a study involving patients and their families to determine their perceptions of evidence-based design features in a new heart center.', 'The CONTEXT also describes how hospitalized patients and their families were surveyed to assess their satisfaction with the environment and identify areas of focus such as privacy, space, noise, light, and overall atmosphere.', 'The ANSWER, however, does not directly address whether patients and their families weigh in on evidence-based hospital design. Instead, it discusses the need for critical care nurses to recognize the influence of the physical environment on care delivery and take steps to maximize patient safety, satisfaction, and quality of care.', 'Therefore, the ANSWER is not faithful to the CONTEXT as it does not provide evidence or information about the involvement of patients and their families in the design process, which is what the QUESTION specifically asks.'], \"SCORE\": FAIL}"
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"content": "{\"REASONING\": ['The context mentions that the etiology of hypospadias involves both genetic and environmental factors.', 'The study focused on monozygotic twins, who share the same genetic constitution, to isolate environmental factors.', 'The data showed that in 16 out of 18 monozygotic pairs discordant for hypospadias, the twin with the lowest birth weight had hypospadias.', 'The mean difference in birth weight was statistically significant (p <0.01), indicating a strong association.', 'Therefore, the answer stating that environmental factors associated with low birth weight are involved in the etiology of hypospadias is supported by the context.'], \"SCORE\": PASS}"
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vllm-b5595f06a7b24ef886b7312210167c72 | 12515417 | {
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"content": "{\"REASONING\": ['The CONTEXT discusses the attitudes, knowledge, and practices of chefs and student chefs regarding healthful food preparation.', 'The CONTEXT mentions that while chefs and student chefs have positive attitudes toward healthful food preparation, their knowledge and practices are not as strong.', 'The CONTEXT specifies that few healthful food preparation practices were likely to be used by any chef group more than two thirds of the time.', 'The ANSWER states that chefs and student chefs are willing to learn about food science and recipe modification principles, which aligns with the positive attitudes mentioned in the CONTEXT.', 'The ANSWER also suggests that dietitians can teach chefs healthful food preparation techniques, which is consistent with the CONTEXT indicating a need for improvement in knowledge and practices.'], \"SCORE\": PASS}"
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vllm-3b6cda66e10e4a549bf4da2939346f6c | 22922655 | {
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"content": "{\"REASONING\": ['The context describes a study where colchicine was tested as a prophylaxis to decrease the severity of lung injury in a neonatal rat model of bronchopulmonary dysplasia (BPD).', 'The study involved three groups of rat pups: a control group, a hyperoxia group, and a hyperoxia + colchicine group.', 'The results showed that colchicine significantly decreased lung damage as measured by the mean linear intercept (MLI), which is a measure of alveolar size.', 'Colchicine also reduced the levels of malondialdehyde (MDA), a marker of oxidative stress, and increased the activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px), which are antioxidants.', 'Furthermore, colchicine-treated pups had lower levels of tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β), which are markers of inflammation.', 'The answer accurately reflects the findings in the context, indicating that colchicine has favorable effects on alveolarization, inflammation, and oxidative stress markers in this animal model of BPD.'], \"SCORE\": PASS}"
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vllm-7e3b267a35504fd1b89c6255c199d723 | 23731651 | {
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"content": "{\"REASONING\": ['The context describes experiments where CCL17 induced a significant increase in CGRP expression and release in human airway epithelial cells.', 'The context mentions that CCR4 was expressed by the cells and internalized after ligation with CCL17.', 'The context also states that CCL17-induced CGRP release was inhibited by a specific anti-CCR4 blocking antibody, indicating CCR4 dependency.', 'The context supports the idea that CCL17 induces CGRP in human airway epithelial cells through CCR4, which aligns with the answer.'], \"SCORE\": PASS}"
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vllm-71fddb39bb9b4ee69a4bf8ee1083549f | 24549772 | {
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"content": "{\"REASONING\": ['The CONTEXT indicates that high education attainment is associated with better patient-reported outcomes, including higher HRQoL and less pain, after THA.', 'The CONTEXT also mentions that individuals with low or medium education are at risk for lower HRQoL and less satisfaction with THA.', 'The ANSWER suggests that clinicians should support patients with low and medium education to a greater extent, which aligns with the CONTEXT findings that these patients may have poorer outcomes.', 'The ANSWER also mentions that identifying and educating patients at risk for poorer outcomes could improve patient satisfaction, HRQoL, pain, and the cost utility of THA, which is consistent with the CONTEXT.'], \"SCORE\": PASS}"
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vllm-53a1b11d123744b88934a9bd6a166d6f | 10837391 | {
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"content": "{\"REASONING\": ['The context describes an experiment where human trabecular cells were exposed to varying levels of hydraulic pressure.', 'The intracellular nitric oxide levels were measured, and peak levels were significantly higher at pressures of 30, 40, and 50 mm Hg compared to 0 and 25 mm Hg.', 'The presence of a nitric oxide synthase inhibitor abolished the fluctuation in nitric oxide levels, indicating that the observed changes were due to nitric oxide production.', 'The context also mentions that the cultured cells expressed brain nitric oxide synthase (bNOS), which is involved in nitric oxide production.', 'The answer correctly summarizes that higher levels of hydraulic pressure enhanced basal production of nitric oxide in human trabecular cells.'], \"SCORE\": PASS}"
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vllm-9376fdd88c4f4beea01aa00d72e0060c | 22248422 | {
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"content": "{\"REASONING\": ['The CONTEXT discusses a study investigating the association between vascular risk factors (VRFs) and the volume of the hippocampus and entorhinal cortex in elderly people.', 'The study found that in men, high total cholesterol and diabetes were significantly or marginally associated with smaller hippocampus and entorhinal cortex.', 'When VRFs such as current smoking, binge alcohol drinking, high cholesterol, and diabetes were aggregated, an increasing number of VRFs were significantly associated with decreasing volume of hippocampus and entorhinal cortex in men.', 'In women, none of the individual VRFs or their aggregation was significantly associated with the volume of these brain regions, except for former smoking which was associated with a larger volume.', 'The ANSWER states that the medial temporal lobe (which includes the hippocampus and entorhinal cortex) is vulnerable to vascular risk factors in men, but not in women, which aligns with the findings presented in the CONTEXT.'], \"SCORE\": PASS}"
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vllm-5e3ab36f7549490e8c5523ec04ee7dfa | 23463625 | {
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"content": "{\"REASONING\": ['The CONTEXT provides detailed results from a randomized phase II trial comparing the efficacy and safety of capecitabine/oxaliplatin (CapOx) plus bevacizumab and dose-modified capecitabine/irinotecan (mCapIri) plus bevacizumab as first-line therapy for metastatic colorectal cancer (mCRC).', 'The primary endpoint was 6 months progression-free survival (PFS), and the results showed promising activity for both combinations, with six-month PFS rates of 76% for CapOx-bevacizumab and 84% for mCapIri-bevacizumab.', 'The CONTEXT also provides median PFS and overall survival (OS) data, which indicate that both combinations have similar efficacy profiles.', 'The CONTEXT mentions that grade 3/4 diarrhea was a predominant toxic effect, occurring in 22% of patients with CapOx-bevacizumab and 16% with mCapIri-bevacizumab, indicating a manageable toxicity profile.', 'The ANSWER accurately reflects the findings from the CONTEXT, stating that both combinations show promising activity and an excellent toxic effect profile, which aligns with the data provided in the CONTEXT.'], \"SCORE\": PASS}"
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vllm-ab69710568764720a4516cfd1347cedc | 23803600 | {
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"content": "{\"REASONING\": ['The context states that CTGF is a key mediator of tissue fibrogenesis in kidney disease and its involvement in renal allograft fibrosis was demonstrated in a mouse model.', 'The context also mentions a prospective study on the association between urinary CTGF (CTGFu) levels and renal allograft fibrosis in human kidney transplant recipients.', 'The study found that CTGFu levels were independently associated with the degree of interstitial fibrosis at 3, 12, and 24 months after transplantation.', 'In a subgroup of patients, higher CTGFu levels at 3 months were associated with moderate and severe interstitial fibrosis developed at 24 months.', 'Based on these findings, the answer that urinary CTGF is associated with human renal allograft fibrogenesis and could serve as a noninvasive biomarker is supported by the context.'], \"SCORE\": PASS}"
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vllm-9822598993a14362aeac29b235411dfc | 25901973 | {
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"content": "{\"REASONING\": ['The context describes macrophages as key players in inflammatory bowel diseases (IBD) and details the effects of specific macrophage subtypes on the intestinal epithelial barrier.', 'It mentions that the lamina propria of the inflamed intestine in IBD patients is infiltrated by CD68 cells, which are positive for inducible nitric oxide synthase and tumor necrosis factor (TNF) α, indicating a proinflammatory state.', 'The context specifies that monocytes and M1 macrophages reduce transepithelial resistance, leading to epithelial barrier disruption, and that this is mediated by the relocalization of tight junction proteins like claudin-2 and epithelial cell apoptosis.', 'The context also notes that M1 macrophages exert their deleterious effects mainly through TNF-α, while monocyte-mediated damage is driven by interleukin-1β and interleukin-18.', 'The answer accurately reflects these points by stating that lamina propria monocytes and M1 macrophages contribute to disrupting the epithelial barrier, leading to intestinal inflammation in IBD.'], \"SCORE\": PASS}"
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vllm-67df89ff8ab14c4893e4dcf2f8a18431 | 23212294 | {
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"content": "{\"REASONING\": ['The CONTEXT indicates that the CH cohort had a greater risk for developing depression compared to the control cohort (aHR = 5.6), but not compared to the migraine cohort (aHR = 1.1).', 'The ANSWER states that CH is associated with an increased risk for depression, which is supported by the data showing a higher risk compared to the control cohort.', 'However, the ANSWER also claims that the strength of this association is similar to that of migraine, which contradicts the CONTEXT where the hazard ratio for CH is significantly higher than for migraine (aHR = 5.6 vs. aHR = 1.1).', 'Therefore, the ANSWER is partially correct but misrepresents the comparison with migraine, making it not fully faithful to the CONTEXT.'], \"SCORE\": FAIL}"
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vllm-26114737c2104ee9ba9ad42bbbddca61 | 25876638 | {
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"content": "{\"REASONING\": ['The context describes an experiment where rats with severe burn injury were treated with exogenous hydrogen sulfide (SH) and a hydrogen sulfide synthase inhibitor (PPG).', 'The results showed that in the SH group, the content of beneficial bacteria (Bifidobacterium and Lactobacillus) increased, while the content of harmful bacteria (Enterococcus, Enterobacter, and Candida albicans) decreased, compared to the burn control group.', 'In contrast, the PPG group showed decreased beneficial bacteria and increased harmful bacteria compared to the burn control group.', 'The answer accurately reflects the findings that exogenous hydrogen sulfide (SH) promoted the growth of probiotics and subdued the growth of pathogenic bacteria, which helps maintain the integrity of the intestinal biological barrier.'], \"SCORE\": PASS}"
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vllm-49ac7a470adc41ac8bf625489f58e86a | 24117047 | {
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"content": "{\"REASONING\": ['The context describes how loop diuretics inhibit the CFTR Cl(-) channel and provides specific details on the kinetics of channel blockade by different loop diuretics.', 'It mentions that bumetanide, furosemide, piretanide, and xipamide were tested using the patch-clamp technique.', 'The context explains that piretanide blockade of CFTR was time and voltage dependent, while furosemide blockade was voltage dependent but time independent.', 'It also describes the speed of channel blockade by furosemide as very fast and by piretanide as intermediate.', 'The answer summarizes these findings by stating that loop diuretics are open-channel blockers of CFTR with distinct kinetics, which is consistent with the detailed information provided in the context.', \"The answer also mentions the potential role of the phenoxy group in bumetanide and piretanide, which is not explicitly stated in the context but is a reasonable inference based on the structural differences mentioned.\"], \"SCORE\": PASS}"
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vllm-83966ac3609a4f64961a06d6d45e8d55 | 26927248 | {
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"content": "{\"REASONING\": ['The CONTEXT indicates that there were no significant differences in the numbers of retrieved oocytes and D3 transferable embryos between the LPOS and GnRH-ant groups.', 'The CONTEXT does show a significantly higher pregnancy rate in the LPOS group compared to the GnRH-ant group.', 'The ANSWER claims that the LPOS protocol can increase the numbers of retrieved oocytes and transferable embryos, which is not supported by the CONTEXT.', 'The ANSWER correctly mentions the higher pregnancy rate in the LPOS group, but it inaccurately represents the findings regarding the number of retrieved oocytes and transferable embryos.'], \"SCORE\": FAIL}"
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vllm-8a2f82ddf6104412988b13bed64edc50 | 11208455 | {
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"content": "{\"REASONING\": ['The CONTEXT describes a study examining the C2077T polymorphism in the hNPRB gene in both myocardial infarction (MI) patients and non-MI control subjects.', 'The study found no significant difference in the distribution of C2077T polymorphism genotypes between MI patients and control subjects (chi 2 = 2.73, p = NS).', 'The allele frequencies of the C2077T polymorphism were also similar between the MI group and the control group.', 'The CONTEXT explicitly states that no association was found between this polymorphism and the clinical diagnosis of MI.', 'The ANSWER correctly reflects the findings from the CONTEXT, stating that the C2077T polymorphism is not a useful marker for the relation between the hNPRB gene and MI.'], \"SCORE\": PASS}"
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vllm-3a1cbd9003304adcb8dcefc61dfa3111 | 23456798 | {
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"content": "{\"REASONING\": ['The context describes a study that compared the miRNA expression profiles of gastric adenocarcinomas and esophageal adenocarcinomas.', 'The study identified specific miRNAs that were deregulated in gastric adenocarcinomas, such as miR-146b-5p, miR-375, miR-148a, miR-31, and miR-451.', 'It also noted that miR-200a was significantly down-regulated in gastric adenocarcinoma samples but up-regulated in esophageal adenocarcinoma samples, indicating a distinct difference in the miRNA signature between the two types of cancer.', 'The context supports the conclusion that gastric adenocarcinoma has a unique miRNA signature that distinguishes it from esophageal adenocarcinoma.'], \"SCORE\": PASS}"
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vllm-f864ca6aa5db405b989915440221595e | 14970115 | {
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"content": "{\"REASONING\": ['The context describes secretoneurin as an abundant neuropeptide located in nerve fibers that interact closely with blood vessels.', 'It mentions that secretoneurin stimulates endothelial cell migration, which is a key process in angiogenesis.', 'The context provides evidence from both in vivo and in vitro experiments supporting the angiogenic effects of secretoneurin.', 'In vivo, secretoneurin-induced neovasculature is characterized by the formation of large diameter and length vessels with endothelial lining and perivascular cell recruitment, indicating vessel maturation.', 'In vitro, secretoneurin-induced capillary tube formation is dose-dependent and specific, confirming direct effects on endothelial cells.', 'Additionally, secretoneurin stimulates endothelial cell proliferation and exerts antiapoptotic effects, activating specific intracellular signaling pathways.', 'These findings collectively support the conclusion that secretoneurin acts as a direct angiogenic cytokine.'], \"SCORE\": PASS}"
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vllm-af80fc6339ae494b9662e4455a137c49 | 21912616 | {
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"content": "{\"REASONING\": ['The CONTEXT describes a study that assessed the relationship between erythropoietin (EPO) levels and malaria-attributable severe disease in children.', 'The study found that EPO levels increase with the severity of malaria, but the values overlap between different study groups.', 'The CONTEXT also mentions that EPO levels are associated with hemoglobin levels, not independently with malaria-attributable severe disease.', 'The ANSWER correctly states that EPO levels are not independently associated with malaria-attributable severe disease due to the overlap of values and the main role of hemoglobin in the expression of EPO.'], \"SCORE\": PASS}"
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vllm-1c7669d7f13943e98c1dcf65292fab9a | 10985887 | {
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"content": "{\"REASONING\": ['The context provides data on the impact of neoadjuvant chemotherapy on cell-mediated immunity in cervical cancer patients.', 'It mentions that NK cell numbers, PBMC cytotoxicity, CD4+/CD28 and CD8+/CD28 T-lymphocyte numbers were higher in patients with a good clinical response to treatment.', 'The context also notes that the addition of IL-12 increased the lytic capacity of PBMC only in the group with a good clinical response.', 'The answer summarizes these findings by stating that NK cell numbers, CD8+ T-cell levels, and CD8+/CD28+ cell levels can be used as prognostic factors before chemotherapy.', 'The answer also correctly interprets that patients with a poor response had lower lytic activity per NK cell and were refractory to IL-12 stimulation, which is supported by the context.'], \"SCORE\": PASS}"
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vllm-5a3ef71ad8534141b6e87c8d029de4fa | 22632167 | {
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"content": "{\"REASONING\": ['The CONTEXT discusses a study examining the association between emotional maltreatment and social anxiety symptoms.', 'It mentions that the study found parental emotional maltreatment and emotional peer victimization to be independently related to social anxiety and general psychopathology.', 'The CONTEXT also notes that subjects with a history of childhood emotional maltreatment showed higher rates of psychopathology than those with a history of physical maltreatment.', 'The ANSWER states that social anxiety symptoms are mainly predicted by emotional rather than physical or sexual types of victimization, which aligns with the findings mentioned in the CONTEXT.', 'Therefore, the ANSWER is faithful to the CONTEXT given the QUESTION.'], \"SCORE\": PASS}"
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vllm-8470935962e04ba8b14c99457f6d0189 | 20476566 | {
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"content": "{\"REASONING\": ['The context discusses the plasticity of characteristic frequency (CF) in rat auditory cortex neurons in response to conditioned stimuli of different sound levels.', 'It mentions that the probability of CF plasticity induced by a conditioned stimulus (CS) is associated with the sound level, with higher sound levels resulting in a higher probability of plasticity.', 'The context also notes that this probability is dependent on the frequency turning curve (FTC) and almost independent of the sound level of the conditioned signal.', 'The answer states that the sound level of the conditioned stimulus differs the plasticity of the characteristic frequency, which aligns with the context provided.'], \"SCORE\": PASS}"
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vllm-f139a462cf5647b69861c3315717f928 | 11426979 | {
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"content": "{\"REASONING\": ['The context describes a study investigating the correlation between gene expression of various angiogenic factors and in vitro invasive activity in human gynecological cancer cell lines.', 'The study found a statistical correlation between VEGF-C gene expression and the number of cells that migrated and invaded (P < 0.01).', 'The context also mentions a close correlation between VEGF-C and MMP-2 gene expression levels (P < 0.05).', 'The answer states that tumor cells producing VEGF-C may have higher invasive and metastatic potential, which aligns with the findings in the context.', 'Therefore, the answer is faithful to the context provided.'], \"SCORE\": PASS}"
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vllm-ae530a959b704ac5918f2c4121453940 | 25613127 | {
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"content": "{\"REASONING\": ['The CONTEXT discusses a study examining the relationship between retinal vessel calibre and diabetic macular ischaemia (DMI) in patients with type 2 diabetes.', 'The study found that patients with moderate or severe DMI had narrower mean retinal arteriolar calibre compared to those with no/mild DMI.', 'The association between narrower retinal arteriolar calibre and moderate/severe DMI remained significant after adjusting for various factors.', 'The ANSWER correctly states that retinal arteriolar narrowing is associated with moderate-to-severe macular ischaemia in eyes with diabetic retinopathy.', \"The ANSWER also suggests that larger vessels other than capillaries may be associated with DMI, which aligns with the CONTEXT's findings on retinal arteriolar calibre.\"], \"SCORE\": PASS}"
},
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vllm-0071c8b7d82e43e4aa299b64f0f564cf | 24366505 | {
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"model": "llama-3-70b",
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"content": "{\"REASONING\": ['The CONTEXT discusses a study investigating the relationship between cerebral saturation and serum S100B levels in infants undergoing cardiac surgery with cardiopulmonary bypass.', 'The study found that while absolute cerebral regional saturation during cardiopulmonary bypass was not associated with S100B elevation, a significant finding was that patients with an arterial-cerebral oxygen saturation difference greater than 50 at any time during cardiopulmonary bypass had a higher S100B peak.', 'The ANSWER states that a wide cerebral arteriovenous difference (which corresponds to the arterial-cerebral oxygen saturation difference mentioned in the CONTEXT) is associated with increased serum S100B in the perioperative period.', 'The ANSWER also suggests that this difference may be a modifiable risk factor for neurological injury, which aligns with the CONTEXT’s implication that S100B elevation is a biomarker of brain injury.'], \"SCORE\": PASS}"
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vllm-6be73c1660984b6f8bccff3f3f0dc96d | 24998254 | {
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"model": "llama-3-70b",
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{
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"message": {
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"content": "{\"REASONING\": ['The context describes a study where aliskiren (ALK) was administered to mice with pressure overload-induced heart hypertrophy and fibrosis.', 'The study found that ALK significantly ameliorated heart hypertrophy, fibrosis, and dysfunction in the mice.', 'The context also mentions that ALK suppressed Ang II-PKCβI-ERK1/2-regulated autophagy, which is the mechanism by which ALK ameliorated these conditions.', 'The answer accurately reflects the findings and mechanisms described in the context.'], \"SCORE\": PASS}"
},
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vllm-fe49c5b0802d4cdabfab4511b06ac378 | 19284557 | {
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"content": "{\"REASONING\": ['The CONTEXT describes a study that analyzed the associations between diet, body composition, lipids, and atheroprotective natural antibodies against phosphorylcholine (anti-PC) in patients with rheumatoid arthritis (RA).', 'The study found that patients with rheumatoid cachexia had significantly higher levels of total cholesterol, LDL, and trendwise oxLDL, as well as lower levels of anti-PC IgM.', 'The CONTEXT also mentions that patients with or without cachexia did not differ in their dietary fat intake or intake of a Mediterranean-like diet.', 'The ANSWER correctly states that rheumatoid cachexia is associated with high levels of LDL cholesterol, low levels of atheroprotective anti-PC, and high frequency of hypertension, which are all relevant to cardiovascular disease (CVD) in RA.', 'The ANSWER also accurately notes that the cachexia could not be related to diet fat intake, which is supported by the CONTEXT.', 'Additionally, the ANSWER mentions that patients on a Mediterranean-like diet had high anti-PC levels, which is consistent with the CONTEXT.'], \"SCORE\": PASS}"
},
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vllm-1d5d980de4d6497f808952c14b246120 | 27033675 | {
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"created": 1719619524,
"model": "llama-3-70b",
"choices": [
{
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"message": {
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"content": "{\"REASONING\": ['The CONTEXT describes a study that analyzed the reliability of a refined definition of the tip-apex distance (TAD).', 'The study involved four raters with varying levels of clinical experience who measured the refined TAD independently.', 'The results showed a strong correlation among all four raters, with an intraclass correlation coefficient (ICC) of 0.998, indicating high interrater reliability.', 'The ANSWER states that the refined TAD is a reliable tool and can be used to develop new TAD recommendations, which aligns with the high ICC value reported in the CONTEXT.', \"The ANSWER also mentions the need for future studies with larger samples to evaluate the predictive value of the refined TAD, which is a reasonable extension based on the CONTEXT's findings.\"], \"SCORE\": PASS}"
},
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"finish_reason": "stop",
"stop_reason": null
}
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vllm-e59755407e954dd5b311a5ea90171cde | 21134374 | {
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"created": 1719619524,
"model": "llama-3-70b",
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{
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"message": {
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"content": "{\"REASONING\": ['The context describes the role of Liver X receptors (LXRs) in lipid metabolism and their impact on hepatic stellate cell activation and fibrotic liver disease.', 'It mentions that LXR ligands suppress markers of fibrosis and stellate cell activation in primary mouse stellate cells.', 'Lxrαβ(-/-) stellate cells produce increased levels of inflammatory mediators and exhibit altered lipid morphology, indicating they are primed for activation.', 'Lxrαβ(-/-) mice show marked susceptibility to fibrosis in two injury models, and bone marrow transplants suggest that altered stellate cell function is the primary cause.', 'The answer states that LXR signaling is a determinant of stellate cell activation and susceptibility to fibrotic liver disease, which is consistent with the findings described in the context.'], \"SCORE\": PASS}"
},
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vllm-ae5c331fec2b492cb3e322d2fd9e154c | 18193068 | {
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"created": 1719619524,
"model": "llama-3-70b",
"choices": [
{
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"content": "{\"REASONING\": ['The CONTEXT describes the effects of ZP120 and N/OFQ on rat mesenteric resistance arteries.', 'It mentions that ZP120 and N/OFQ did not relax arteries contracted with noradrenaline or adenosine-triphosphate.', 'EFS-evoked contractions were inhibited by ZP120 and N/OFQ, and this inhibition was not affected by endothelial removal or pretreatment with capsaicin.', 'The alpha(2)-adrenoceptor antagonist rauwolscine did not alter the inhibition by ZP120 and N/OFQ, suggesting it is not mediated by alpha(2)-adrenoceptors.', 'The competitive NOP receptor antagonist UFP-101 prevented the inhibitory effect of N/OFQ but not ZP120, indicating distinct modes of interaction with the NOP receptor.', 'The ANSWER states that the vasodilator effect is mediated by prejunctional inhibition of adrenergic neurotransmission, which aligns with the findings in the CONTEXT.'], \"SCORE\": PASS}"
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"total_tokens": 890,
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vllm-a99feeedaabe4dd7ae132de93a501dfe | 18699941 | {
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"object": "chat.completion",
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"model": "llama-3-70b",
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"content": "{\"REASONING\": ['The context indicates that IL-13 was measurable in only 6 out of 34 subjects with COPD and was not found in control subjects.', 'The context also mentions a paucity of IL-13+ cells in both COPD subjects and controls.', 'The answer states that the findings do not support a role for IL-13 in COPD, which aligns with the context showing limited presence of IL-13 in sputum and bronchial mucosal samples.', \"The answer also highlights the increase of T cells in bronchial glands in COPD, which is supported by the context mentioning an increase in CD3(+) lymphocytes within bronchial glands in COPD.\"], \"SCORE\": PASS}"
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vllm-9a26eaf91108483989c1f8115c60c424 | 20543553 | {
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"content": "{\"REASONING\": ['The context describes a study that analyzed the effects of EMF on FRTL-5 cells, specifically looking at iodide uptake and cAMP production.', 'The results of the study showed that irradiation of FRTL-5 cells with EMF at 900 MHz for 24, 48, and 96 hours did not influence the level of cAMP production and did not modify iodide accumulation compared to basal conditions.', 'The answer states that EMF do not seem to be able to interfere with the biochemical properties of FRTL-5 cells in vitro, which aligns with the findings presented in the context.'], \"SCORE\": PASS}"
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vllm-3459a5f8ee1e4554bbc1bed71c7b9429 | 8822660 | {
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"content": "{\"REASONING\": ['The context mentions that the development of advanced endoscopic instrumentation has demonstrated the superiority of direct visual examination over radiographic demonstration.', 'The context provides specific statistics comparing hysteroscopy and hysterosalpingography (HSG), showing that HSG has low specificity and positive predictive value.', 'The context states that hysteroscopy found a normal uterine cavity in a significant percentage of cases where HSG indicated abnormalities.', 'The answer accurately reflects the information in the context by stating that hysteroscopy is superior to HSG in identifying intrauterine pathology and suggests replacing HSG with hysteroscopy as a first-line investigation.'], \"SCORE\": PASS}"
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"content": "{\"REASONING\": ['The context describes the development and evaluation of a recombinant Newcastle disease virus (NDV) vaccine expressing West Nile virus (WNV) proteins.', 'The vaccine, rLa-WNV-PrM/E, was tested in various species including mice, horses, chickens, ducks, and geese.', 'The results showed that the vaccine induced significant immune responses in all these species, including neutralizing antibodies and T-cell responses in mice, and WNV-specific IgG in horses, chickens, ducks, and geese.', 'The context explicitly states that the vaccine elicited significant immune responses in both mammals (mice and horses) and poultry (chickens, ducks, and geese).', 'Therefore, the answer stating that the vaccine is immunogenic in mammals and poultry is directly supported by the context.'], \"SCORE\": PASS}"
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vllm-e3f983721d384629b4bb5bf31a2d5b4a | 27284688 | {
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"content": "{\"REASONING\": ['The CONTEXT describes a study using TMS-EEG to explore cortical function and connectivity in individuals with ASD and matched controls.', 'The study found no differences in the EEG response to TMS between the ASD and control groups, which aligns with the QUESTION about revealing no electrophysiological abnormality.', 'The ANSWER correctly states that TMS-EEG did not identify any differences in EEG response between ASD and control groups, indicating no electrophysiological abnormality.', \"The additional information in the ANSWER about the relationships between the neurophysiological response to TMS and clinical characteristics is consistent with the CONTEXT, which mentions correlations between traits and characteristics associated with ASD and the neurophysiological response to TMS.\"], \"SCORE\": PASS}"
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"content": "{\"REASONING\": ['The context describes a study examining the influence of other opioid receptor systems on KOP-mediated antinociception.', 'It mentions that KOP receptor agonists are aversive and suggests that KOP-mediated antinociception might be a form of stress-induced analgesia.', 'The context specifically states that pretreatment with the DOP agonist SNC80 blocked KOP-mediated antinociception by systemic U50,488H in wild-type mice.', 'The answer correctly summarizes that systemic DOP receptor agonists blocked systemic KOP antinociception, which is supported by the context.'], \"SCORE\": PASS}"
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"content": "{\"REASONING\": ['The context discusses the variation in TAS2R pseudogenes and their potential role in human evolution.', 'It mentions that some TAS2R pseudogenes show evidence of substantial diversification among species, suggesting a dynamic role.', 'The context specifically highlights the cases of TAS2R6P and TAS2R18P, which have unique patterns of variation that may be influenced by selection.', 'The answer summarizes these findings by stating that the similar distribution of variation in many pseudogenes suggests a unidirectional loss of function, but notes exceptions like TAS2R6P and TAS2R18P that imply a more complex history.', 'The answer also correctly interprets the data for TAS2R6P as being influenced by balancing selection on the TAS2R5 gene and for TAS2R18P as suggesting an acquired function followed by recent pseudogenization.', 'Therefore, the answer is faithful to the context as it accurately reflects the findings and interpretations presented.'], \"SCORE\": PASS}"
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vllm-08afc6099c93499397665d63da74744d | 9551677 | {
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"content": "{\"REASONING\": ['The CONTEXT indicates that the C282Y mutation in the HFE gene is more frequent in patients with porphyria cutanea tarda compared to controls, suggesting it may be a predisposing factor.', 'The CONTEXT also mentions that hepatitis C virus infection is present in a significant proportion of patients with porphyria cutanea tarda and that none of these patients carried the C282Y mutation, indicating independence.', 'The ANSWER correctly summarizes these findings by stating that the C282Y mutation and hepatitis C virus infection are likely independent cofactors for porphyria cutanea tarda.'], \"SCORE\": PASS}"
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vllm-43a98ae8f6544de89ab5fb37ff61de2f | 23574883 | {
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"content": "{\"REASONING\": ['The CONTEXT provides detailed information about a study that analyzed the allelic and genotype frequencies of two LINGO1 variants (rs9652490 and rs11856808) in both MS patients and healthy controls.', 'The study found no significant difference in the allelic and genotype frequencies of these variants between MS patients and controls, with p-values of 0.853 for rs9652490 and 0.773 for rs11856808.', 'The CONTEXT also mentions that allele and genotype frequencies were unrelated to the age of onset of MS, gender, and clinical course of MS, and that haplotype analyses did not reveal any putative risk related to haplotypes.', 'The ANSWER correctly states that LINGO1 rs9652490 and rs11856808 polymorphisms are not related to the risk for MS, which aligns with the findings presented in the CONTEXT.', \"The additional information in the ANSWER about the potential usefulness of these SNPs as risk biomarkers for essential tremor but not other movement disorders is consistent with the CONTEXT's indication that these SNPs have been associated with other neurological conditions.\"], \"SCORE\": PASS}"
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vllm-1a7aafeabf0a49dc827864432bc50adf | 20890680 | {
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"content": "{\"REASONING\": ['The context provides a comparison between levetiracetam and phenytoin in terms of cognitive outcomes and seizure incidence in patients with intracranial hemorrhage (ICH).', 'It mentions that levetiracetam is known to cause less cognitive disruption compared to phenytoin.', 'The study results show that patients receiving levetiracetam had higher Glasgow Coma Scores, lower seizure incidence, and a higher rate of being discharged home compared to those receiving phenytoin.', 'Although the difference in cognitive function retention rate did not reach statistical significance (P = 0.08), it suggests a trend in favor of levetiracetam.', 'The answer accurately reflects the findings in the context, indicating that levetiracetam is associated with better cognitive outcomes and fewer seizures compared to phenytoin.'], \"SCORE\": PASS}"
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vllm-cec6d7d96daa448a85451c39ed410e19 | 16481245 | {
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"content": "{\"REASONING\": ['The context describes a study on rats with nitrofen-induced congenital diaphragmatic hernia (CDH) and the effects of vitamin A on Pax3 expression.', 'It is mentioned that Pax3 expression is significantly decreased on E13 and E15 in the hearts of nitrofen-treated embryos and remains decreased, although not significantly, on E21.', 'The context also states that vitamin A recovers Pax3 expression on E13, partially on E15, and above normal levels on E21.', 'The answer accurately reflects these findings by stating that Pax3 is underexpressed in the hearts of nitrofen-exposed embryonal rats on days 13th and 15th of gestation and tends to be lower than normal near term, and that vitamin A up-regulates this expression on the 3 endpoints.'], \"SCORE\": PASS}"
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vllm-eea4da098f6848d4a0f11b7975b9f95e | 24106773 | {
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"content": "{\"REASONING\": ['The CONTEXT provides detailed information about a study examining the relationship between fruit and vegetable intake, vitamins C and E, and the prevalence of cataract in a Spanish Mediterranean population.', 'The study found that increasing quartiles of combined fruit and vegetable intake were associated with a decreasing reduction of odds of cataract or cataract extraction, with a statistically significant trend (P for trend = 0.008).', 'For vitamin C, the study found a significant decreasing association with the prevalence of cataract or cataract extraction from intakes of 107 mg/d, with a statistically significant trend (P for trend = 0.047).', 'For vitamin E, a protective association was found from intakes of 8 mg/d, but no linear trend was observed across quartiles of intake (P for trend = 0.944).', 'The ANSWER states that high daily intakes of fruit and vegetables and vitamins C and E were associated with a significantly decreased prevalence of cataract or cataract surgery, which aligns with the findings in the CONTEXT.', 'The ANSWER also mentions that the study reinforces the WHO recommendations on the benefits of diets rich in fruit and vegetables, which is consistent with the CONTEXT.'], \"SCORE\": PASS}"
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vllm-b32a303588d44c2596c5ba137f505525 | 17854601 | {
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"content": "{\"REASONING\": ['The context describes how RB loss leads to increased tumor multiplicity, higher proliferation rates, and compromised genome integrity in mouse liver tumors.', 'It also mentions that genes up-regulated by RB loss are associated with chromosomal instability and poor survival in human HCC patients.', 'The answer accurately reflects these findings by stating that RB deletion enhances tumorigenesis, increases hepatocyte proliferation, and compromises genome integrity.', \"The answer also correctly suggests that evaluating RB status may be useful for prognosis in human HCC, which is supported by the context's mention of poor survival prediction.\"], \"SCORE\": PASS}"
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"completion_tokens": 127
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vllm-01abe34243484e4f99da161aea1c39c9 | 21892586 | {
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"content": "{\"REASONING\": ['The CONTEXT discusses the effects of Lactobacillus plantarum CECT 7315/7316 on intestinal transit and nutritional status in the elderly.', 'The CONTEXT does not provide a direct statement about the improvement of general health or quality of life.', 'The ANSWER claims that the consumption of functional foods containing L. plantarum CECT 7315/7316 improves the quality of life in elderly subjects, which is not directly supported by the CONTEXT.'], \"SCORE\": FAIL}"
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vllm-f6573b817d434a78858dfc502b7c67be | 21963958 | {
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"content": "{\"REASONING\": ['The CONTEXT describes a study (SONIC) that showed combination therapy with infliximab and azathioprine (IFX/AZA) is more effective than infliximab (IFX) alone for Crohn\\'s disease.', 'The CONTEXT mentions that the number and types of adverse events were roughly equivalent between the groups, but the study was limited, making it unclear how rare adverse events would affect overall outcomes.', 'The CONTEXT explains that a decision model was constructed to compare the risks and benefits of IFX/AZA versus IFX monotherapy, using parameters from SONIC and other published literature.', 'The CONTEXT provides specific thresholds for serious infections (20% or more) and lymphoma (3.9% or more) above which the risks of IFX/AZA would outweigh its benefits. These thresholds are significantly higher than the base-case estimates.', 'The ANSWER states that the benefits of IFX/AZA outweigh the risks based on 1-year SONIC data, unless serious adverse events occur at higher rates than seem clinically realistic.', 'The ANSWER is consistent with the CONTEXT, as it reflects the findings that IFX/AZA is more effective and that the risks would only outweigh the benefits at very high incidence rates of serious adverse events.'], \"SCORE\": PASS}"
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}
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"completion_tokens": 267
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} | null |
vllm-c4ac395353b04f898cdb03e25bb39090 | 16483579 | {
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"content": "{\"REASONING\": ['The CONTEXT indicates that serum GGT levels were higher in men who experienced coronary events compared to those who did not.', 'The CONTEXT provides statistical evidence that GGT was a significant predictor of incident myocardial infarction, with hazard ratios increasing across GGT quartiles.', 'However, the CONTEXT also mentions that further adjustment for other cardiovascular risk factors attenuated the association, suggesting that GGT is not entirely independent of other risk factors.', 'The ANSWER claims that serum GGT is a strong predictor independent of other risk factors, which contradicts the CONTEXT that shows the association was attenuated after adjusting for other factors.'], \"SCORE\": FAIL}"
},
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"finish_reason": "stop",
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"completion_tokens": 137
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vllm-b1b6cdf141ee44dfb1c02d4873b8a8e5 | 16174723 | {
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{
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"message": {
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"content": "{\"REASONING\": ['The context provides information about the V89L polymorphism in the SRD5A2 gene and its association with hypospadias.', 'It states that the valine version of the enzyme is more efficient than the leucine version.', 'The study found a significant negative association for the V89 allele in hypospadias, indicating that the valine allele is associated with a reduced risk of hypospadias.', 'The odds ratio and confidence interval provided support this conclusion.', 'The answer correctly summarizes that the valine allele of the V89L polymorphism confers a reduced risk for hypospadias.'], \"SCORE\": PASS}"
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"completion_tokens": 143
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vllm-70259fed99f44ea082f164eb4585e3bd | 15136629 | {
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"model": "llama-3-70b",
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{
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"message": {
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"content": "{\"REASONING\": ['The CONTEXT describes a study evaluating fast PET/CT imaging protocols using LSO detector technology and 3D image-acquisition protocols.', 'The study involved 57 patients with varying weights, and PET emission scans were acquired for different durations (1, 3, and 4 minutes per bed position).', 'The observers analyzed the images and identified lesions, comparing the detectability and image quality across different scan durations.', 'The results showed that lesion detectability was similar for 1, 2, and 3-minute scans compared to the 4-minute scans, with only a few lesions missed on the 1-minute scans.', 'The ANSWER states that LSO PET detector technology allows for fast 3D imaging protocols with weight-based emission scan durations ranging from 1 to 3 minutes per bed position, providing similar lesion detectability compared to 4-minute scans.', 'This is consistent with the findings in the CONTEXT, making the ANSWER faithful to the CONTEXT.'], \"SCORE\": PASS}"
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"logprobs": null,
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"completion_tokens": 208
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vllm-65dfa320658c49bf8b00e8035d9b9fcd | 7943112 | {
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"model": "llama-3-70b",
"choices": [
{
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"message": {
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"content": "{\"REASONING\": ['The CONTEXT provides detailed information about a study investigating the levels of tumor necrosis factor-alpha (TNF-alpha) in plasma and amniotic fluid during pregnancy.', 'The study included healthy pregnant women in their second trimester (group A) and found that TNF-alpha was detected in the plasma of 78.2% of these women.', 'The CONTEXT explicitly states that TNF-alpha was not detected in any of the amniotic fluid specimens studied.', 'The ANSWER correctly reflects these findings by stating that levels of TNF-alpha were elevated in the plasma but not detected in the amniotic fluid of normal pregnant patients in the second trimester.', \"The ANSWER also provides additional interpretation about the involvement of the immune system and the possible role of TNF-alpha in regulating trophoblast growth and invasion, which is consistent with the CONTEXT's mention of the immune system's adaptation to pregnancy.\"], \"SCORE\": PASS}"
},
"logprobs": null,
"finish_reason": "stop",
"stop_reason": null
}
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"usage": {
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"total_tokens": 829,
"completion_tokens": 195
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vllm-a7245a08837f4a2b9dfd23573de2b407 | 24397850 | {
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"message": {
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"content": "{\"REASONING\": ['The context discusses the impact of age on the quality and functionality of human adipose tissue-derived mesenchymal stem cells (hAT-MSCs).', 'It mentions that advanced age is negatively correlated with an organism\\'s reparative and regenerative potential.', 'The study found that aged MSCs displayed senescent features, reduced viability, and proliferation compared to cells from young donors.', 'Aged MSCs also had significantly reduced differentiation potential compared to young MSCs.', 'The answer accurately reflects the findings in the context, stating that advancing age negatively impacts stem cell function, which could be detrimental for successful stem cell therapies.'], \"SCORE\": PASS}"
},
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"finish_reason": "stop",
"stop_reason": null
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"usage": {
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"total_tokens": 591,
"completion_tokens": 140
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vllm-92751ce2bb0f46cc8a11c3de8f642ee1 | 21544513 | {
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"choices": [
{
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"message": {
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"content": "{\"REASONING\": ['The context describes a study aimed at testing the hypothesis that ingestion of oxidized fat causes activation of transcription factors NF-κB and Nrf2 in the small intestinal mucosa of mice.', 'The study involved administering oxidized or fresh fat to mice, and after 6 days, the nuclear concentration of NF-κB and Nrf2 and the expression of related genes were measured.', 'The results showed that oxidized fat markedly increased the nuclear concentration of NF-κB and Nrf2 and the transcript levels of oxidative stress-responsive genes.', 'The answer states that dietary oxidized fat activates the oxidative stress-responsive transcription factors NF-κB and Nrf2 in the intestinal mucosa of mice, which is consistent with the findings described in the context.'], \"SCORE\": PASS}"
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"content": "{\"REASONING\": ['The context describes a study where plasma samples from VC-exposed workers and unexposed individuals were analyzed using metabolomics.', 'The study identified 613 unique metabolites, with 189 increased and 94 decreased in the VC-exposed group.', 'The metabolite signature could separate the groups with 94% accuracy, indicating significant changes in the plasma metabolome.', 'Specific changes included increased long chain and essential fatty acids, lipid peroxidation products, and decreased carnitine and carnitine esters.', 'The context also mentions that differentially regulated metabolites interact with ERK1/2, Akt, AMPK, and the NMDA receptor.', 'The top canonical pathways affected included tRNA charging, nucleotide degradation, amino acid synthesis/degradation, and the urea cycle, with altered 1-carbon metabolism.', 'The answer accurately reflects these findings by stating that occupational exposure generated a distinct plasma metabolome with markedly altered lipid and amino acid metabolites and identifying the protein targets for vinyl chloride toxicity.'], \"SCORE\": PASS}"
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"content": "{\"REASONING\": ['The context mentions that the mean values for NOVA and AVL [Mg2+] differed significantly for smokers (0.41 vs 0.52 mmol/L, respectively).', 'It also notes a significant intramethod difference in NOVA [Mg2+] between smokers and nonsmokers, with a dose-dependent decrease in NOVA [Mg2+] observed with an increase in cigarettes/day.', 'The context specifies that NOVA [Mg2+] inversely correlated with white blood cell counts.', 'The answer states that smoking may induce a serum factor, possibly related to white blood cells, that negatively interferes with the response of the NOVA Mg ISE.', 'This aligns with the context, which indicates that there is an interaction between smoking, white blood cells, and the NOVA Mg ISE that affects the measurement of serum ionized magnesium concentration.'], \"SCORE\": PASS}"
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"content": "{\"REASONING\": ['The CONTEXT provides data from a prospective study of 10,648 female twins from the Danish Twin Registry.', 'The study found that early menarche (defined as menarche before 12 years of age) was associated with a higher cumulative incidence of asthma compared to girls without early menarche (7.4% vs. 4.5%).', 'The odds ratio (OR) for asthma was 1.71 (1.31-2.22) for girls with early menarche, and this association remained significant after adjusting for BMI, current age, physical activity, education, and smoking (OR = 1.53, 1.15-2.04).', 'The unadjusted risk of asthma increased by 8% (1-15%) for each year earlier menarche occurred.', 'While the co-twin control analysis did not show a significant association, the overall results suggest a complex relationship between early menarche and asthma risk.', 'The ANSWER accurately reflects the findings from the CONTEXT, stating that early menarche is associated with an increased risk of asthma independently of various factors and suggesting a complex relationship.'], \"SCORE\": PASS}"
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"content": "{\"REASONING\": ['The context describes a study investigating the effects of aging on endothelial dysfunction in a murine model of sepsis.', 'It mentions that both eNOS deficiency and aging exacerbated mortality and multiple organ dysfunction syndrome (MODS) in mice with sepsis.', 'The context provides evidence of endothelial dysfunction in both eNOS-deficient and aged mice, including vascular oxidative damage and plasma markers of endothelial dysfunction.', 'The context also states that the severity of endothelial dysfunction may predict mortality in mice with sepsis.', 'The answer summarizes these findings by stating that endothelial dysfunction may be an early predictor and independent contributor to sepsis-associated MODS and mortality in aged mice.', 'Therefore, the answer is faithful to the context provided.'], \"SCORE\": PASS}"
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"content": "{\"REASONING\": ['The context indicates that short-chain fatty acids (SCFAs) can induce pro-inflammatory cytokine production, but only at high concentrations (20 mM). Lower levels did not induce cytokine secretion.', 'The context also mentions that SCFAs can enhance the production of pro-inflammatory cytokines when combined with specific Toll-like receptor (TLR) ligands, such as TLR2 and TLR7 ligands.', 'The answer correctly summarizes that SCFAs, especially in combination with TLR ligands, contribute to a pro-inflammatory environment.', \"The answer's statement about furthering our understanding of how BV affects susceptibility to microbial infections is consistent with the context, which mentions BV and increased susceptibility to HIV infection.\"], \"SCORE\": PASS}"
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vllm-a793f77eb1194d95854763c947610286 | 27261559 | {
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"content": "{\"REASONING\": ['The context describes a study examining the relationship between the rate of increase in lung-to-head ratio (LHR) and postnatal survival in left-sided congenital diaphragmatic hernia (CDH) patients.', 'The study found that the rate of LHR increase was significantly higher in long-term survivors compared to non-survivors (p=0.0175).', 'The answer states that the interval increase in LHR levels over the course of gestation correlates with survival in left-sided CDH patients, which aligns with the findings in the context.', 'The answer also suggests that regular ultrasonographic re-evaluation of LHR throughout gestation may provide prognostic insight and help guide patient management, which is consistent with the context.'], \"SCORE\": PASS}"
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vllm-b2df5da325d34c409796e51781967f64 | 24690247 | {
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"content": "{\"REASONING\": ['The context provides data from a study evaluating the impact of adding MRI scans to conventional clinical staging for guiding decisions about radiotherapy target coverage.', 'The study found that extracapsular extension was incorporated into target volumes significantly more often with the addition of mT-staging (46 patients, 40%) compared to cT-staging alone (37 patients, 32%), with a P-value of 0.002.', 'Seminal vesicle invasion was also incorporated into target volumes significantly more often with the addition of mT-staging (21 patients, 18%) compared to cT-staging alone (three patients, 3%), with a P-value of <0.001.', 'A total of 23 patients (20%) had changes to their target coverage based on the mT-staging.', 'These findings indicate that MRI scans do significantly change target coverage decisions in radical radiotherapy for prostate cancer, supporting the answer.'], \"SCORE\": PASS}"
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"content": "{\"REASONING\": ['The context discusses the role of noradrenalin transporters (NET) and noradrenalin (NE) fibers in regulating dopamine (DA) levels in different brain regions of Parkinsonian rats.', 'It mentions that NET blockers potentiate the effect of L-DOPA in certain regions (PFC, SNr, and HIPP) but not in the striatum, indicating region-dependent regulation.', 'The context also notes that destruction of NE fibers potentiates L-DOPA effect in SNr and HIPP, further supporting the involvement of noradrenalin neurons in DA regulation.', 'The answer correctly summarizes that noradrenalin neurons are indirectly involved in the mechanism of action of L-DOPA, particularly in extrastriatal regions, which aligns with the findings presented in the context.'], \"SCORE\": PASS}"
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vllm-85e6dfe8525e4976861a744cd56ed36b | 20573805 | {
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"content": "{\"REASONING\": ['The context provides data on the long-term renal function in children with PH-I who underwent pre-emptive liver transplantation (PLT).', 'The study compared the renal function of four children with PH-I who had PLT with eight controls who had liver transplantation for other reasons.', 'The context mentions that at 2 years post-transplantation, there was no significant difference in eGFR between the two groups (72 vs 100 mL/min/1.73 m(2), respectively; P = 0.06).', 'The context also notes that renal function reduced by 21 and 11% in the PH-I group compared with 37 and 35% in the control group at 12 and 24 months, respectively, indicating a slower decline in renal function in the PH-I group.', 'The answer states that renal function remains relatively stable following pre-emptive liver transplantation for PH-I, which aligns with the data showing a slower decline in renal function in the PH-I group compared to the controls.', 'The answer also mentions that early diagnosis and isolated liver transplantation may prevent progression to end-stage renal disease, which is supported by the context indicating relatively stable renal function in the PH-I group.'], \"SCORE\": PASS}"
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vllm-32426804adb34b509d61ccdd34d15f8a | 25887553 | {
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"content": "{\"REASONING\": ['The CONTEXT discusses the conservation of group B Sox proteins and their binding patterns in Drosophila species.', 'It mentions that the function of common binding and its evolutionary conservation is not fully known.', 'The CONTEXT describes a study that examined the binding patterns of Dichaete and SoxNeuro in four species of Drosophila.', 'The study found that while binding site turnover is widespread, binding is preferentially conserved at known cis-regulatory modules and core binding sites.', 'The strongest binding conservation was observed at sites commonly bound by Dichaete and SoxNeuro, suggesting these sites are functionally important.', 'The ANSWER states that common binding by redundant group B Sox proteins is evolutionarily conserved in Drosophila, which aligns with the findings in the CONTEXT.'], \"SCORE\": PASS}"
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vllm-546ab6ccb5e9488d9aadf44fa303d91d | 25249235 | {
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"content": "{\"REASONING\": ['The context describes a study that examined the effect of metformin on developing pancreas and beta cells.', 'It mentions that metformin treatment led to an increase in the proliferation and number of pancreatic progenitors (PDX1(+)) in vitro.', 'The context also states that metformin administration to pregnant mice induced an increase in both PDX1(+) and neurogenin 3-positive progenitors in the embryonic pancreas at E14.0.', 'These changes resulted in an increased beta cell fraction in neonates.', 'The answer accurately reflects these findings by stating that exposure to metformin during gestation modulates the early steps of beta cell development towards an increase in the number of pancreatic and endocrine progenitors, ultimately resulting in a higher beta cell fraction at birth.'], \"SCORE\": PASS}"
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vllm-93a325abe0d7453e8490940d18c5607b | 9403530 | {
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"content": "{\"REASONING\": ['The context describes an experiment where thymocytes were heated to induce HSP 70 and then irradiated to determine if HSP 70 protects against radiation-induced apoptosis.', 'The results showed that induction of HSP 70 increased basal apoptosis but significantly decreased radiation-induced apoptosis.', 'The protective effect of HSP 70 was reversed when an HSP 70 antisense oligomer was introduced, indicating that HSP 70 is responsible for the protection.', 'The context also mentions that HSP 70 induction suppressed p53 and decreased bax levels, which are associated with apoptosis.', 'The answer accurately reflects the findings in the context, stating that HSP 70 induction protects thymocytes from radiation-induced apoptosis by down-regulating p53 and bax expression.'], \"SCORE\": PASS}"
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