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In this report we present four patients treated with a combination of different psychotropic drugs, in whom asterixis was triggered either by adding carbamazepine (CBZ) to a treatment regimen, or by increasing its dosage.
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SUBJECTS AND METHODS: Our case observations attempted to evaluate nine alcoholics after withdrawal suffering from persisting craving, sleep disorder, excitement, depressive symptoms or anxiety symptoms.
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A 71-year-old woman who had critical cerebral ischemia secondary to a carotid artery occlusion was receiving high-dose intravenous phenylephrine for a trial of hypertensive therapy.
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The most commonly recognized toxic effect of ethambutol is optic neuropathy, which generally is considered uncommon and reversible in medical literature.
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His lung cancer recurred 10 months later, when he was found to have bone metastases.
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We conjectured that the side effects of insulin, such as anti-natriuresis and increased vascular permeability, might be pronounced in the presence of the hepatic dysfunction that accompanies insulin insensitivity, hyperinsulinaemia and hypoalbuminaemia.
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At present, the child is growing on by GH replacement therapy.
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Goiter and hypothyroidism during re-treatment with amiodarone in a patient who previously experienced amiodarone-induced thyrotoxicosis.
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S-A conduction through two pathways, the first with 2/1 block the second having 0.12-0.14 s longer conduction time and with occasional 2/1 block was proposed for the explanation of the alternating P-P interval and other electrocardiographic features seen.
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Acute Liver Failure Study Group.
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Schneiderian first-rank symptoms associated with fluvoxamine treatment: a case report.
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The course of this rare case is described and the literature reviewed.
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We believe that mucositis was a contributing factor to this case of fatal hyperkalemia after administration of succinylcholine, with a mechanism similar to that reported with thermal injury.
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We have successfully overcome severe neutropenia in an RA patient treated with gold salts, using granulocyte colony-stimulating factor (G-CSF), reducing the duration of neutropenia and risk of infection.
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In this article, we describe a Japanese patient with severe interstitial pneumonia probably caused by sorafenib treatment for metastatic renal cell carcinoma.
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To our knowledge, this is the first case report that demonstrates the occurrence of fever with low-dose amifostine therapy without the manifestation of accompanying rash or hypotension.
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DISCUSSION: After exclusion of other causes, the onset of thrombocytopenia after administration of lansoprazole, the resolution of the adverse reaction after discontinuation of the drug, and the fact that no other medicines were introduced during this time frame lead us to believe that this was most likely an idiosyncratic thrombocytopenic response to lansoprazole.
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The combination of GM-CSF to accelerate hematological recovery and the possibility of administering large doses of a liposomal form of Amphotericin B were the contributing factors to the resolution of the infection.
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By continuous irrigation it is frequently used to treat suppurative mediastinitis after median sternotomy.
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Multidrug-resistant, progressive, invasive diffuse spinal aspergillosis: case report and review of the literature.
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Complete disappearance of the primary tumor and involved inguinal lymph nodes was achieved with three courses of the cis-platinum-containing chemotherapy regimen BMP administered prior to radiotherapy.
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We report a patient with advanced colonic carcinoma who was treated with concomitant chemoirradiation with oxaliplatin and developed a peculiar dermnatitis in the irradiated field after being exposed to subsequent chemotherapy with oxaliplatin.
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This patient developed sequential symptoms including alternative hemiparesis, dysarthria and altered consciousness 5 days after the second course of HD-MTX (8 gm/m2 by 6 h continuous infusion) with leucovorin rescue.
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A review of the current literature was undertaken to examine the effects of antidiabetic agents on cardiovascular disease, and with the help of illustrative patient case examples, useful information is provided for clinicians to individualize therapy for patients with type 2 diabetes.
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Acute myeloid leukemia and lung cancer occurring in a chronic lymphocytic leukemia patient treated with fludarabine and autologous peripheral blood stem-cell transplantation.
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Although combinations of belladonna, ergotamine, and phenobarbital have been used for medical treatment of menopausal symptoms since the 1960s, this is the first known case report of its association with anticonvulsant hypersensitivity syndrome.
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Since both hypothyroidism and iron deficiency anemia may coexist, additional thyroid function testing is recommended in patients treated concurrently with ferrous sulfate and L-thyroxine.
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His treatment was initiated with tacrolimus (dose of 0.15 mg/kg/day) in two divided doses along with prednisolone 60 mg/m(2)/daily.
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We present a pediatric patient with leukemia and a severe, L-asparaginase-induced necrotizing pancreatitis, treated successfully with percutaneous drainage used to flush the infected necrotic parts.
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Administration of excessive insulin induced hypoglycemia within 4 to 8 hours, followed by rebound hyperglycemia.
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Differences were found in the categories of seriousness and outcome of the reported ADRs between patients and healthcare professionals.
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Pediatric neurosurgeons commonly instill vancomycin into the ventricles to treat shunt infections.
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Cardiac time intervals of a fetus in labor can be presented, which did not change significantly throughout the first stage of labor.
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Five patients showed grade 3 and 4 adverse reactions, all hematological.
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The risk factors for this presentation remain undefined.
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Twenty-nine patients with gynaecological cancers who received over 400 mg of doxorubicin were monitored electrocardiographically to determine whether cardiac glycosides countered the adverse effects of high total doses of doxorubicin.
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Children who are treated with topiramate should have a careful history taken preoperatively looking for signs of a metabolic acidosis and baseline blood chemistries should be measured prior to surgery to detect an asymptomatic metabolic acidosis.
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The following data set was acquired: the type of caustic agent, the time of the burns, the delay and type of immediate treatment and the time and type of first aid, the subsequent medication, the clinical grading and the later results.
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Leakage from a conjunctival break created during trabeculectomy may cause serious complications such as shallow anterior chamber, hypotony, and a flat bleb in the early postoperative period.
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We report a case of SJS in a 14-year-old male with nephrotic syndrome, who was treated with oral prednisolone for 6 weeks.
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METHOD: Case analysis of a poly-drug overdose (venlafaxine, topiramate, divalproex sodium, risperidone, and carbamazepine) presenting with mixed SS/NMS features and whose clinical management suggests a practical algorithm for treatment of undifferentiated SS/NMS in critical care settings.
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Lichenoid drug eruption to salsalate.
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We present the first case (to our knowledge) of a potentially serious drug-drug interaction between zafirlukast and theophylline.
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However, other factors or drugs (e.g. cresol) are thought to induce MH.
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METHODS: A 40-year-old female with a 3-year history of panic disorder was prescribed fluvoxamine 50 mg day(-1) in addition to clorazepate dipotassium and sulpiride.
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The treatment for acidosis and hyperkalaemia should be started as soon as RTA is diagnosed, and the dosage of FK506 should also be reduced if possible.
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CASE HISTORY: A 58-year-old male Caucasian developed delayed onset diffuse lamellar keratitis, seemingly in the absence of an epithelial defect, 25 days following an enhancement LASIK procedure to his right eye.
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Hypernatraemia induced by sodium polystyrene sulphonate (Kayexalate) in two extremely low birth weight newborns.
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We present a case of antisynthetase syndrome whose predominant feature was fibrosing alveolitis and which may have been drug-induced.
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Despite the withdrawal of ampicillin and aggressive systemic and wound care, the infant died.
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However, they subsequently were shown to be associated with propranolol.
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It has become key to treating attention deficit-hyperactivity disorder (ADHD) in children and adolescents.
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Long-term treatment with high-dose corticosteroids exposes patients to potentially serious adverse effects.
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The severity of uremia in patient 2 could be one of the conditions that, in association with the abrupt changes obtained with IVPMP, predispose to neurological manifestations.
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HUS has been reported after several anticancer chemotherapies and most often after mitomycin C-based chemotherapy regimens.
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The case of a bipolar patient who developed thyrotoxicosis with severe exophthalmos while on lithium therapy is described.
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MR of the brain was performed in eight patients (mean age, 14.9 years) with osteogenic sarcoma during or after IV treatment with high-dose methotrexate.
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Portopulmonary hypertension recurred when the transplanted liver failed and again resolved after a second liver transplantation.
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However, 1 eye had vitreous hemorrhage after repeated injections of tPA.
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A 52-year-old woman was seen in our outpatient clinic for pain and numbness in the left lower lip and chin, which developed following an endodontic treatment for her mandibular left second premolar.
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Ototoxicity as a result of cis-platinum administration is well documented.
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The following is a case report analysis intended to draw attention to the need for better care coordination by describing the observed relationship of olanzapine to metabolic changes manifested as uncontrolled diabetes mellitus and weight gain.
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There is a possible association between eosinophilia and myocarditis, a life-threatening condition.
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We present a unique case of a patient, without any prior history of a movement disorder, who developed tics following a single dose of atomoxetine that did not improve until interventional therapy was initiated.
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The study was approved by the McGill University Health Centre Research Ethics Board.
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Three of the four airmen experienced undesirable HbA1c levels.
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The use of sodium thiosulfate seemed to be a reasonable nonspecific therapeutic approach for the management of TC in this case.
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The authors present an elderly patient with mixed dementia who developed TD at multiple sites, (including respiratory dyskinesia [RD], limb dyskinesia, and orofacial dyskinesia) following abrupt withdrawal of risperidone therapy.
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On day 13, a 24-hour urine collection had a protein excretion of 3151 mg.
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In our case, the seeding might have been related to the type of needle used and the multiple passes required to treat the liver lesion.
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Although numbness of the left arm was not improved, her overall pain score was reduced by 2 on the 7th day after the start of SKT.
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We are unaware of any previous cases of statin-mediated unmasking of RMD.
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Dalteparin, an LMWH, was started at a maximum dose of 18,000 units subcutaneously once daily, according to British national prescribing guidelines.
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Basal and secretin-stimulated gastrin responses were suppressed but not normalized.
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PURPOSE Perivascular epithelioid cell tumors (PEComas) represent a family of mesenchymal neoplasms, mechanistically linked through activation of the mTOR signaling pathway.
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Recurrent bacteremia by Chryseobacterium indologenes in an oncology patient with a totally implanted intravascular device.
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Just after the initiation of the partial CPB, high inspiratory airway pressure was suddenly recognized.
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One suspicious mechanism is the low content of calcium ion stabilizing proteins such as hyaluronate or fetuin in treatments for severe eye burns.
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CSA was withdrawn, and a new MRI was normal after 2 months.
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Development of pemphigus herpetiformis in a patient with psoriasis receiving UV-light treatment.
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The patient was treated with oral prednisolone 70 mg/day on a tapering schedule.
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Effects of esomeprazole on the pharmacokinetics of atazanavir and fosamprenavir in a patient with human immunodeficiency virus infection.
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The connective tissue disease was characterized by an erythematous rash, hair loss, nephritis, splenomegaly, seizures, and coma.
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There was no evidence of residual basal cell carcinoma.
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Atrial fibrillation following methylprednisolone pulse therapy.
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In addition to its known effect on gallbladder stasis, octreotide alters bile acid composition and may thus hasten intrahepatic sludge and stone formation.
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These cases suggest the possibility that, in some patients, leukopenia or agranulocytosis during olanzapine treatment might be dose-related.
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Although the manifestations are the same as those usually associated with the use of vincristine, in these cases the severity appears remarkable.
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We describe the current data on sorafenib and challenges faced in patients with HCC.
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FK506, which began to be administered 12 days earlier, rose to a level of 44 ng/mL (normal range, 10-20 ng/mL) 1 day before neurologic abnormalities began.
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Two days after administration of Kalimate enema, he had profuse hematochezia, and a sigmoidoscopy showed diffuse colonic mucosal necrosis in the rectum and sigmoid colon.
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Around 1990, psychologists and educators began to notice increasing use of methylphenidate by students.
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A small initial dose of prazosin ranging from 0.5 to 1 mg has been recommended to avoid the first-dose phenomenon characterized by a sudden and severe drop in blood pressure after the administration of the first dose of prazosin.
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Monitoring DPD activity may be important in the management of patients experiencing severe toxicity secondary to FUra chemotherapy.
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A patient with chronic myeloid leukaemia treated with busulphan for 4-5 years, developed signs of busulphan toxicity and portal hypertension with ascites, oesophageal varices and jaundice.
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For treatment of this condition he was given androgens and corticosteroids.
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Furthermore, a chest CT scan in case 1 and an arteriography in case 2 confirmed the PTE-related hypoperfusion.
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The patient was started on intravenous calcium gluconate.
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There were some temporal periods of good tolerance between these episodes.
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The patient then became psychotic again and has since experienced periodic phases similar to the previous illness.
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