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The antiviral effect of lamivudine was fair, and no objective side effect was experienced during the transplant procedure.
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Four weeks earlier she had developed hepatopathy during a regimen of carbamazepine, lynestrenol and sodium valproate.
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Cutaneous side effects, namely acneiform eruption, xerosis, telangiectasia, hyperpigmentation, fissures, hair and nail changes, are reported in literature.
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A twelve year-old-girl with idiopathic partial epilepsy with secondary generalization, developed acute psychosis 10 days after the administration of levetiracetam.
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The multiple comedones and ruptured epidermoid cysts are newly reported adverse effects of imiquimod therapy.
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Recently, many cooperative groups use dexamethasone instead of prednisone during induction.
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Many drugs, especially antibiotics, can produce this untoward effect.
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The use of methotrexate (MTX) has been contraindicated for treatment of severe psoriasis in HIV infection on the basis of six previously reported cases in which MTX appeared to potentiate opportunistic infections and accelerate HIV disease.
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All three had been diagnosed earlier with epilepsy, and their electroencephalogram (EEG) findings were abnormal.
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One year later, decreased fluency and mild ataxia persists.
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The patient was admitted to the hospital for exacerbation of heart failure.
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OBJECTIVE: To report four patients with antinuclear antibody-positive migratory arthralgias and acute inflammation unrelated to the underlying inflammatory bowel disease, fulfilling the criteria of a drug-induced lupus-like syndrome.
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This case report demonstrates the lack of adverse events in a pediatric patient administered nesiritide beyond the recommended dosing parameters.
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This case is unique because of the measurement of olanzapine in brain tissue obtained from seven regions in addition to the commonly collected biologic matrices.
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This therapy was also complicated by Warfarin-induced skin necrosis.
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Therapy with ATG should be considered in childhood severe aplastic anemia when bone marrow transplantation is not possible.
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Even after a strict warning, he took another quinine tablet that evening, which triggered his fifth episode of severe thrombocytopenia, and confirmed the etiology of quinine-induced thrombocytopenia.
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The patient was discharged on oral methylprednisolone and has not had recurrence of the skin lesions.
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OBJECTIVE: To report two cases of fixed drug eruption induced by methylphenidate.
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Treatment with methotrexate and prednisone.
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The relation between tacrolimus treatment and staining was suggested by the appearance of pigmentation during topical tacrolimus treatment and its clinical disappearance when treatment was stopped.
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Toxoplasma polymyositis was diagnosed in a dog given repeated injections of glucocorticoids for a skin condition.
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She developed a generalized rash and itching, sore throat, and dizziness approximately 4 hours after the first dose of capecitabine.
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A rare adverse effect is a localized lipoatrophy at the site of injection, which has previously been observed and described in 11 patients.
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Fever and maculopapular rashes appeared at 10 days after phenytoin initiation, and then the drug was discontinued.
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Severe rash, including the Stevens-Johnson syndrome (SJS), is the major toxicity of nevirapine and is described in the package labeling with a prominent, boxed warning.
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Possible side effects of tPA injection, such as increased intraocular pressure and corneal edema, were not observed.
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Two lines were inserted by a cut-down technique into the external jugular and one line by the percutaneous technique into the subclavian vein.
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Methicillin-resistant Staphylococcus aureus osteomyelitis of the scaphoid from a catheter in the radial artery.
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In case no. 2, the pathogenic mechanism seemed to be persistent light reaction preceded by systemic photoallergy, as he had taken mequitazine for 6 months, and there were strong positive photopatch test results with immediate erythema reaction, cross-reaction to promethazine, decreased MED to both UVA and UVB, and persistence of the photosensitivity over a 3-year follow-up period after discontinuation of the mequitazine.
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Evaluation at another laboratory showed normal levels of TSH, raising the possibility of interfering substances.
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We discuss the possible common immunological basis for these two diseases and the risks and benefits of immunosuppressive therapy.
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The symptoms arose within 3-5 min after immersion in water, as a white sponge-like appearance, and resolved after a variable drying period.
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Cell-mediated immune reactions mediated by OKT8+T cells might have caused the leukopenia, although other mechanisms involving cytotoxic antibodies or antibody-dependent cell-mediated cytotoxicity cannot be excluded.
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BACKGROUND: Previous studies indicate that photodynamic therapy provides effective relief from biliary obstruction in advanced cholangiocarcinoma.
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All-trans retinoic acid has revolutionized the treatment of acute promyelocytic leukemia, but this therapy is often complicated by the all-trans retinoic acid syndrome.
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Administration of infliximab and adalimumab gave excellent clinical response but was discontinued due to adverse events.
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The patient's diabetic misconceptions remained, but he appeared to gain sufficient insight to prevent recurrent hypoglycaemia.
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The most common symptoms are fever (78%), abdominal pain (92%), and cloudy dialysate (90%); 76% of cases had a predominance of polymorphonuclear cells in peritoneal fluid.
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We believe that total cyclosporine withdrawal is feasible, but strongly recommend overlapping mycophenolate mofetil treatment with cyclosporine.
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In view of the close time association between the start of chemotherapy and the acute onset of massive embolism other explanations, such as spontaneous necrosis, must be considered less likely.
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Although clonazepam therapy is not new, it appears to have been omitted from current pain texts and journals as a treatment option for phantom limb pain.
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After analysis of the case, ruling out other possibilities and using the Naranjo probability scale, we found that there is a highly probable likelihood that the symptoms presented by our patient were secondary to his drug therapy.
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While she was receiving the maximum dose of 180 mg/day of cinacalcet HCl and PTH at 443 pg/mL, she needed to be hospitalized for a right hip prothesis.
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After taking the first tablet, she developed dyspnea, cough, and wheezing.
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PATIENT: A 46-yr-old female with ventilator-dependent, proliferative-phase acute respiratory distress syndrome complicated by Pseudomonas aeruginosa bacteremia and sepsis.
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CONCLUSIONS: We have seen an increased incidence of acute INH neurotoxicity because of the resurgence of TB in New York City.
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Antineutrophil cytoplasmic antibody-positive crescentic glomerulonephritis associated with propylthiouracil therapy.
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Moreover, the presented cases serve as a link in a spectrum of hepatic disorders recently recognised to be caused by environmental agents such as vinyl chloride, arsenic, and thorotrast, and by contraceptive and anabolic steroids.
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INTERVENTION: A 50-year-old female with bilateral canalicular obstruction secondary to docetaxel therapy received botulinum toxin injections (5 units each) into the lacrimal glands of both eyes.
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The patient was positive for antibody against complexes of heparin and platelet factor 4, and was diagnosed as heparin-induced thrombocytopenia with thrombosis syndrome (HITTS).
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Serial electrocardiograms revealed a minimally and asymptomatically prolonged QT interval.
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BACKGROUND: Interferon (IFN)-associated retinopathy is typically characterized by retinal hemorrhages and cotton wool spots at the posterior fundus, but visual function is usually maintained.
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The development of cutaneous ecchymosis associated with a sudden fall in hemoglobin after the administration of alteplase should strongly suggest the possibility of diffuse subfascial hematoma.
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The case of a bipolar patient who developed thyrotoxicosis with severe exophthalmos while on lithium therapy is described.
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Drug provocation test is important in this case to confirm which drug had caused hypersensitivity reaction because anti tuberculosis drugs were the treatment of choice for her illness.
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Resolution of the symptoms was observed in both patients when interferon alpha was withdrawn.
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Rebound hyperglycemia following overdosing of insulin in cats with diabetes mellitus.
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We report an HIV-infected woman who developed mild leukopenia as the first sign of a nevirapine-related adverse event, which was followed by skin and hepatic toxicity associated with a more severe leukopenia.
| 1 |
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An 83-year-old man receiving glipizide 10 mg bid developed symptomatic hypoglycemia within three days of adding trimethoprim/sulfamethoxazole (TMP/SMX) to his regimen.
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INTRODUCTION: Despite high success rates with free-tissue transfer, flap loss continues to be a devastating event.
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While the combination of daily oral steroids and daily oral cyclophosphamide dramatically improves the outcome of WG, this therapy is not without serious side effects.
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Anhedonic ejaculation with desipramine.
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Cutaneous adverse effects during therapy with an epidermal growth factor receptor (EGFR) inhibitor.
| 0 |
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We report a case of an infant with complex congenital heart disease who was placed on captopril for afterload reduction following cardiac surgery and subsequently developed pulmonary infiltrates with eosinophilia.
| 1 |
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Electrocardiogram (ECG) on arrival and at 3 hours showed no acute changes; cardiac enzymes revealed minimal MB elevation.
| 0 |
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Most clinicians are routinely exposed to irritants such as latex, detergents, and chemicals.
| 0 |
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None of these patients experienced a relapse of their PTLD with follow-up ranging from 1.5 to 5 years.
| 0 |
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We describe a 14-year-old bone marrow transplant recipient who was anti-HBs-positive before the procedure and afterwards developed acute infection with hepatitis B virus (HBV).
| 0 |
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Inadvertent substitution of acetohexamide for acetozolamide.
| 0 |
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Methylphenidate-associated enuresis in attention deficit hyperactivity disorder.
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Caution is advised in administering arginine to patients with renal or hepatic insufficiency, or both.
| 0 |
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After recovery, in an attempt to provide adequate calories and to elucidate the inciting agent, he was rechallenged with his original total parenteral nutritional solution which contained 500 ml/day of a 20% fat emulsion.
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Ideally, a urethral bulking agent should be non-immunogenic and biocompatible, leading to minimal inflammatory and fibrotic response.
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Rhabdomyolysis in patients with acute lymphoblastic leukemia.
| 0 |
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METHODS: We report a patient who had an anaphylactic reaction during the intravenous infusion of cyclosporine.
| 1 |
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We describe in detail the first U.S. case report, of a 4(1/2)-year-old boy who experienced angioedema during treatment with oxcarbazepine.
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Reports of this phenomenon in animals are reviewed.
| 0 |
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Adding Dantrolene and Oxybutynin elevated the blood level of Carbamazepine, possibly by inhibition of cytochrome P450.
| 0 |
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A 63-year-old man presented with an 11-month history of progressive myoclonus in the right abdominal wall.
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Epstein-Barr virus-associated lymphoproliferative disorder in a patient with rheumatoid arthritis on methotrexate and rofecoxib: idiosyncratic reaction or pharmacogenetics?
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Surgical management of primary hyperhidrosis by upper dorsal sympathectomy is the treatment of choice for intractable hyperhidrosis, however, paradoxically it may be followed by troublesome compensatory hyperhidrosis in a significant number of patients.
| 0 |
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Elevated muscle enzymes and findings on electromyography were consistent with myopathy.
| 0 |
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By repeated testing other causes of diarrhea, e. g., infectious diarrhea including Clostridium difficile colitis were excluded.
| 0 |
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Acute or chronic infections or inflammatory conditions can exacerbate anemia in patients on dialysis.
| 0 |
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Two patients had elevated cone thresholds at least one year later.
| 0 |
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Our patient had headache, mild fever, nausea, vomiting, rash, and eosinophilia after 3 weeks of disulfiram therapy.
| 1 |
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We describe the side effects of 5-FU in a colon cancer patient who suffered severe mucositis, desquamating dermatitis, prolonged myelosuppression, and neurologic toxicity that required admission to the intensive care unit.
| 1 |
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We present a case of progressive disseminated aspergillosis that involved multiple sites in a bone marrow transplant recipient with severe, chronic graft-versus-host disease.
| 0 |
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Nummular headache (NH) is a primary headache adopting the form of local pain in a circumscribed area of < 7 cm in diameter in the tuber parietale, albeit it may also be located in other areas of the head.
| 0 |
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The pertinent literature on ergotism is reviewed, and it is emphasized that ergotism may develop in patients on therapeutic doses of the drug.
| 0 |
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Less common adverse events to dapsone include the idiosyncratic reactions of leukopenia and agranulocytosis, cutaneous eruptions, peripheral neuropathy, psychosis, toxic hepatitis, cholestatic jaundice, nephrotic syndrome, renal papillary necrosis, severe hypoalbuminemia without proteinuria, an infectious mononucleosis-like syndrome, and minor neurological and gastrointestinal complaints.
| 1 |
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Her case was complicated by social and behavioral issues.
| 0 |
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Therefore, other immunosuppressive agents have been used to replace glucocorticoids in the long-term treatment of autoimmune hepatitis, including azathioprine, a purine analogue.
| 0 |
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Renal toxicities have been reported in less than one percent of the patients receiving ciprofloxacin therapy.
| 1 |
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RESULTS: Pathologic gambling has emerged as one of the most prominent ICDs, although hypersexuality, compulsive shopping and other manifestations of obsessive-compulsive disorder may also dominate PD-related behavioral manifestations.
| 0 |
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Previous studies have noted the difficulty in performing accurate injections into this area.
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The pathogenesis appears to be multifactorial but involves rapidly rising vasoconstrictor tone in renal and systemic vascular beds.
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6-Thioguanine is being increasingly used in the treatment of inflammatory bowel disease but has not been reported to cause liver injury in this context.
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She developed SIADH 48 hours following chemotherapy.
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