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Acute myopathy with selective degeneration of myosin filaments following status asthmaticus treated with methylprednisolone and vecuronium.
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The increasing use of this agent is expected, because of the increasing number of patients with inflammatory bowel disease.
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Fatal venous thrombembolism complicating imatinib therapy in a patient with metastatic gastrointestinal stromal tumor.
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OBJECTIVE: To report the safe use of fluorouracil in a patient with breast cancer who had allergic reactions to capecitabine.
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The patient experienced two episodes of angioedema within a 10-hour period.
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We describe a patient with acute myeloblastic leukemia (AML) who developed nephrotic syndrome after receiving several courses of chemotherapy, including macrophage-colony-stimulating factor (M-CSF).
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The ocular toxicity of DCF, previously described as conjunctivitis, appears to be a keratitis of moderate severity which requires further study.
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Thymic enlargement in a patient with juvenile idiopathic arthritis during etanercept therapy.
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This case illustrates that the hemophagocytic syndrome associated with reactivation of EBV can occur as part of drug hypersensitivity reactions in RA patients taking sulfasalazine.
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Intravenous levodopa 25 mg ameliorated his akathisia symptoms drastically.
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With this case report, we bring to attention the association of the MVI shortage and WE.
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Toxicity related to chloroquine treatment of resistant vivax malaria.
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Several hours after the last dose, clinical manifestations recurred and ventilation was required.
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An asthmatic patient with corticosteroid treatment for 45 years presented with slowly progressive limb muscle atrophy.
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She required vasopressor therapy for intraoperative hypotension and developed severe headache immediately after administration.
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Clinical and laboratory signs of liver injury resolved over the next few days, with a return to baseline levels of AST and ALT levels over the subsequent months.
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Satisfactory initial results over the first few months of treatment were achieved when the new preparation was given to Transvaal patients known to have these disorders and hitherto treated in vain.
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The combination of levodopa and peripheral dopadecarboxylase inhibitor is the most efficacious symptomatic treatment for Parkinson's disease.
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Successful treatment of disseminated cutaneous phaeohyphomycosis in a dog.
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The authors report 9 cases of dystonic reactions in patients with dementia following the initiation of antipsychotic medication.
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Despite a hematologic response in all 3 patients, none of them achieved cytogenetic remission, and all progressed to blast crisis at 7 to 10 months of imatinib therapy.
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In case no. 2, the pathogenic mechanism seemed to be persistent light reaction preceded by systemic photoallergy, as he had taken mequitazine for 6 months, and there were strong positive photopatch test results with immediate erythema reaction, cross-reaction to promethazine, decreased MED to both UVA and UVB, and persistence of the photosensitivity over a 3-year follow-up period after discontinuation of the mequitazine.
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Fatal liver failure following generalized tonic-clonic seizures.
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Complications associated with primary and secondary perforation of the bladder following immediate instillations of epirubicin after transurethral resection of superficial urothelial tumours.
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Amebic abscess of the spleen complicated by metronidazole-induced neurotoxicity: case report.
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FK506 is an immunosuppressant that is thought to be less nephrotoxic than cyclosporine A.
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The infant was fully breast-fed, and the neonatal lamotrigine serum concentration was 4.87 microg/mL at the time of admission.
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However, given the clinically significant result to the interaction between tolazoline and cimetidine we report, the use of cimetidine in tolazoline induced upper gastrointestinal hemorrhage should deserve more attention.
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This is the 1st case documenting intrathecal IgG synthesis and immune complex formation in this disorder.
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Methylphenidate (Ritalin)-associated cataract and glaucoma.
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A patient with acute changes suggesting acute hepatitis after parenteral amiodarone administration is described.
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CLINICAL RELEVANCE: Pancreatic neoplasms are associated with a poor prognosis, regardless of treatment modality.
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We report a 59-year-old patient with chronic myeloid leukemia, who developed severe interstitial lung fibrosis after short term and sequential treatment with melphalan and busulfan.
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Life-threatening acute hyponatraemia induced by low dose cyclophosphamide and indomethacin.
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The subject is a 66-year old woman, with a negative medical history of atopy, food and drug allergy, with arterial hypertension on a course of beta-blockers and with bladder carcinoma requiring surgery.
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With the use of optical coherence tomography (OCT), two patients with IFN-associated retinopathy who had developed macular edema and reduced visual acuity during the clinical course of IFN therapy were observed.
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The corn oil-based soft gelatin capsule appears to be the safest formulation.
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The extent of disease and subsequent reversal were documented using arteriographic examination.
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We report a 50-year-old male patient with a 15-year history of psoriasis including mutilating psoriatic arthritis, in whom the withdrawal of cyclosporin A induced a generalised pustular exacerbation and a aggravation of the joint condition.
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Treatment of total hyphema with relatively low-dose tissue plasminogen activator.
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BACKGROUND: Posterior reversible encephalopathy syndrome (PRES) is characterized by abnormalities in cerebral white matter and neurologic symptoms.
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CONCLUSIONS: In any patient under clopidogrel (Plavix): Sanofi-Synthelabo, Bristol-Myers Squibb/Sanofi Pharmaceuticals) therapy and with a typical clinical presentation, SSEH should be suspected and quickly diagnosed, regardless of hemostatic status or the absence of other major risk factors.
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When catheter disconnection, kink, or dislodgement is not visible on X-ray, radioisotopic control is a safe and reliable method for assessment.
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Despite close monitoring of therapy, he experienced two episodes of unexpected and prolonged hypercalcemia.
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STUDY DESIGN: Case reports are presented of three premature infants (mean gestational age 27 weeks) cared for in the intensive care nursery in whom clinically significant septal hypertrophy and left ventricular outflow tract obstruction developed during dexamethasone treatment for bronchopulmonary dysplasia.
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Fatal radiation myelopathy after high-dose busulfan and melphalan chemotherapy and radiotherapy for Ewing's sarcoma: a review of the literature and implications for practice.
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We suggest that sarcoidosis may develop in chronic hepatitis C patients during interferon alpha and/or ribavirin treatment, and diagnostic tests for this adverse effect should be performed during the follow-ups.
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Tardive dyskinesia in an adolescent.
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He had been taking trimethoprim-sulfamethoxazole for approximately eight days when he revisited his family physician, complaining of headaches, dizziness, difficulty with speech, weakness, and itching on the trunk of his body and legs, where a maculopapular rash was noted.
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Treatment of tardive dyskinesia.
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Patient examination 3 months after surgery revealed a large, central, full-thickness corneal infiltrate with multiple satellite lesions in the right eye.
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RESULTS: Complete removal of the tumor was performed.
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Correction after vitamin K administration suggested an organophosphate-related effect on vitamin K-dependent factor VII activity.
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Ocular examinations revealed intraocular pressure (IOP) of 30 mmHg under medication, dense posterior subcapsular opacity of lens, pale disc with advanced cupping, and marked constriction of visual field.
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We examined the effect of total parathyroidectomy (PTX) on renal anemia in 20 dialysis patients with secondary hyperparathyroidism.
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Very low thiopurine methyltransferase activity represents the TPMTL/TPMTL genotype, and can be detected before therapy with azathioprine is started.
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RESULTS: Eleven of the 32 patients (34.4%) developed retinopathy.
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In the present study we describe two patients with different types of reaction patterns, one presenting as an allergic, the other as an irritant contact dermatitis.
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This review presents the first case series of DIC associated with acute hemoglobinemia or hemoglobinuria following anti-D IGIV administration for ITP.
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Cutaneous lichenoid eruptions can arise as a result of exogenous compound exposures.
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We report a case of a 69-year-old male patient who came to our attention for macular edema in hemiretinal vein occlusion.
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Serotonin syndrome induced by transitioning from phenelzine to venlafaxine: four patient reports.
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Glucocorticoid-induced osteoporosis (GIO) is an important problem that remains undertreated, even by rheumatologists.
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The ECG pattern of BS has also been described in patients with myocardial abnormalities.
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Amifostine-induced fever: case report and review of the literature.
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Amiodarone treatment did not abolish the thyroid radioactive iodine uptake (RAIU), allowing for subsequent treatment with radioactive iodine.
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Multiple periarticular abnormalities appearing on serial radionuclide bone scanning of the cancer patient, particularly when symmetric and in a distribution not suggestive of osseous metastatic disease, raise the possibility of multifocal osteonecrosis.
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Two of 13 patients treated over the entire body suffered temporary bone marrow depression, indluding one with severe pancytopenia.
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CASE REPORT: A 45-year-old woman had complicated Crohn's disease with multiple fistulae and only 1 m of residual small bowel.
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The syndrome commonly presents with pruritus and increased muscle tone.
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The patient was extubated 1 week later.
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DESIGN: Observational case report.
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Short cardiopulmonary resuscitation restored spontaneous circulation and the patient recovered completely.
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Pressure-induced interface keratitis: a late complication following LASIK.
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Children treated with thalidomide should undergo regular neurophysiologic studies in order to detect presymptomatic or progressive peripheral neuropathy.
| 0 |
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This report describes a patient who developed pulmonary leukostasis in the absence of significant leukocytosis.
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Necrotizing pancreatitis after transcatheter arterial chemoembolization for hepatocellular carcinoma.
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Octreotide administration rapidly reversed hypoglycemia allowing patient stabilization and eventual discharge without any significant adverse events.
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On reduction of the intrathecal baclofen dose, complete return to baseline sexual function was achieved for both subjects.
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He had an extensive psychiatric history significant for schizophrenia and multiple past hospital admissions, starting at age 14 years.
| 0 |
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In any patient with 'unexplained' muscle spasms or convulsions, strychnine poisoning should be included in the differential diagnosis and they should be asked about the use of herbal medicines.
| 0 |
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Since, in some cases of eye burns, we have found corneal calcifications to be related to the initial calciferous caustic agents and to the use of phosphate-buffer-containing fluids, we have reviewed our files of clinical eye burns for the incidence and appearance of corneal calcification.
| 0 |
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There were significant correlations between a change in Scr on the one hand and changes in BW and UV, Scr and serum albumin on the other.
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Prehospital diagnosis was established by portable blood analyser and an early antidote with 4 MP treatment initiated in out-of-hospital setting.
| 0 |
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The apparent low adverse effect profile of the new drug zafirlukast has made it an attractive choice in the treatment of asthma.
| 0 |
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No cases of renal acidosis, and only one case of nephrogenic diabetes insipidus, has been previously reported as a complication of foscarnet treatment.
| 1 |
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Case study: a modified topical treatment regimen for sodium warfarin-induced necrotizing fasciitis.
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Drug-induced hepatotoxicity is an important cause of hepatocellular injury.
| 0 |
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Fluorescein angiography was performed to confirm the presence of neovascularization.
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On the eleventh day after the surgery, she experienced dyspnea and chest pain during standing and walking exercise.
| 0 |
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Reteplase was administered with concomitant lepirudin.
| 0 |
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CONCLUSION: Severe and sustained ocular hypertension may occur after intravitreal ranibizumab.
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CASE: A 29-year-old primigravida with a history of four therapeutic amniocenteses for idiopathic polyhydramnios developed preterm labor at 30 and 5/7 weeks' gestation, rupture of membranes, and Candida albicans chorioamnionitis.
| 0 |
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While successful treatment may require surgical intervention in some cases, others may respond to antibiotic therapy alone.
| 0 |
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The reaction was aborted with diphenhydramine and dexamethasone.
| 0 |
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Ocular hypertension occurred 1 month after the second ranibizumab injection in patients 1 and 3, and 1 month after the first ranibizumab in patient 2.
| 1 |
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Mycophenolate mofetil substitution for cyclosporine-dependent myasthenia gravis and nephrotoxicity.
| 0 |
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It is important to be aware of these rare complications, which are correlated with the prognosis.
| 0 |
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DISCUSSION: The clinical presentation of ELP is nonspecific and ranges from the totally asymptomatic patient with incidental radiologic finding, like our patient, to the patient with acute or chronic symptoms attributable to pneumonia, pulmonary fibrosis, or cor pulmonale.
| 0 |
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A massive digitoxin (DGTX) intoxication in a 36-year-old man (35 mg DGTX) was treated by prolonged and repeated i.v.-infusions of Fab fragments of anti-digitalis antibodies (FAB).
| 0 |
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