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CASE: A malignant mixed mesodermal tumor was diagnosed in a 64-year-old woman with a bicornuate uterus while she was taking raloxifene for osteoporosis prevention.
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In case no. 2, the pathogenic mechanism seemed to be persistent light reaction preceded by systemic photoallergy, as he had taken mequitazine for 6 months, and there were strong positive photopatch test results with immediate erythema reaction, cross-reaction to promethazine, decreased MED to both UVA and UVB, and persistence of the photosensitivity over a 3-year follow-up period after discontinuation of the mequitazine.
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The objective was to determine the effects of cholesterol-lowering agents on neurologic features and to develop a noninvasive method of monitoring clinical response.
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DIAGNOSIS: Severe temozolomide-induced immunosuppression, exacerbated by corticosteroids, with profound T-cell lymphocytopenia and simultaneous opportunistic infections with Pneumocystis jiroveci pneumonia, brain abscess with Listeria monocytogenes, and cutaneous Kaposi's sarcoma.
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This case study discusses the new products and traditional treatment products used and presents results of irritant specificity testing and a series of photographs documenting resolution and healing.
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Clinical manifestations including vomiting, diarrhoea and dyspnoea were identical in both cases.
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Irinotecan therapy in a 12-year-old girl with recurrent brain stem glioma and without functional polymorphisms in UGT1A1 activity: case report.
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Two cases of sacroiliitis due to P. avidum have been reported.
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We report a patient with pulmonary adenocarcinoma complicated by the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) following systemic chemotherapy with cisplatin (CDDP) and vindesine (VDS).
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The noted increase in the theophylline level after zafirlukast administration is in contrast to the original reports by the manufacturer.
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An infant who developed pancreatitis during meglumine antimoniate treatment for visceral leishmaniasis and who was successfully treated with a combination of allopurinol and ketoconazole is reported.
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Fine-needle aspiration cytology (FNA) showed a pleomorphic adenocarcinoma in both the breast and axilla.
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This etiology has to be considered in patients taking this drug who present with intraocular inflammation.
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These may include 1) symptoms or history of mood spectrum disorder, 2) history of psychosis, 3) female sex, 4) family history of psychiatric disorder.
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When the data of the 57 patients are evaluated, a reversible direct cytotoxic effect of ticlopidine on the pluripotent/bipotent hematopoietic progenitor stem cell is proposed.
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Methylphenidate and dextroamphetamine-induced peripheral vasculopathy.
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Coexistence of psoriasis and subacute cutaneous lupus erythematosus (SCLE) is unusual.
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The patient experienced hallucinations, agitation, vomiting, tachycardia and seizures after ingestion of 1050 (48 mg/kg) of extended-release bupropion.
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A 22-year-old female with renal failure secondary to focal segmental glomerulosclerosis underwent a deceased donor kidney transplant and presented 3 months later with pyelonephritis; the urine culture grew Kluyvera ascorbata.
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We describe a case of subcutaneous metastasis along the needle track after percutaneous ethanol injection (PEI) for treatment of hepatocellular carcinoma.
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We report a case of a patient with pulmonary hypertension and undifferentiated connective tissue disease who, after 2 months of treatment with epoprostenol, presented with rapidly progressive erythema, scaling, nausea and vomiting, and fever.
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Acne provoked by gold seems not to have been described elsewhere.
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Two months after insertion and following a course of chemotherapy the lower end of the stent eroded the mucosa of the second part of the duodenum causing severe gastrointestinal hemorrhage which necessitated laparotomy and trimming of the stent.
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Of particular interest in the present case report is the silent presentation and the absence of any pharmacological interference.
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In all three patients, the diagnosis of AML was established by pathologists on the basis of bone marrow biopsy, aspirate, and peripheral smears.
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Despite this improvement, the patient became resistant to the clozapine titration schedule due to complaints of sedation.
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Acidic and neutral drugs were screened for by liquid-liquid extraction followed by high-performance liquid chromatography-diode-array detection.
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We describe the case of a nonatopic 17-year-old girl with bronchial asthma and aspirin intolerance who developed a dramatic anaphylactic reaction to oral prednisone.
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Erosion of psoriatic plaques: an early sign of methotrexate toxicity.
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Management of immunocompromised patients with diffuse pulmonary infiltrates remains a common and stubbornly difficult problems.
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Surgical evacuation of the laryngeal hematoma was not necessary.
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Two months later she was bedridden.
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Their plasma cell dyscrasias were evaluated with immunofixation electrophoresis of serum and urine specimens, quantitative serum lgs, and immunohistochemical staining of bone marrow biopsy specimens.
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Microscopic examination of these colonies showed a high percentage of histiocytes identical to those seen in the patient's bone marrow.
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Fibrinous anterior uveitis following laser in situ keratomileusis.
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Associated thyreoiditis, myasthenia gravis, thymectomy, Chron's disease, and erythema nodosum: pathogenetic and clinical correlations, immune system involvement, and systemic infectious complications.
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Further signs were hyperhidrosis, hypersalivation, bronchorrhoea, and severe miosis; the electrocardiographic finding was atrio-ventricular dissociation.
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DATA SOURCES: Case reports and review articles identified by MEDLINE.
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Severe rhabdomyolysis following massive ingestion of oolong tea: caffeine intoxication with coexisting hyponatremia.
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Hymenoptera sting can lead to an acute myocardial infarction by different pathogenetic mechanisms depending on the presence of preexistent coronary atherosclerosis, the development of shock or the therapeutic use of epinephrine.
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Peritonitis due to Aspergillus and zygomycetes in patients undergoing peritoneal dialysis: report of 2 cases and review of the literature.
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OBJECTIVE: To predict the effectiveness of alcohol neurolysis in the treatment of persistent pain caused by the entrapment of superior cluneal nerves.
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Dexamethasone 4 mg orally twice daily was given around the time of chemotherapy administration to prevent the dermatitis associated with the drug.
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RESULTS: Recurrences in both eyes were successfully treated with a combination of hexamidine and neomycin, and with polyhexamethylene biguanide respectively.
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Two patients who developed decreased visual acuity after several months of ethambutol treatment for Mycobacterium avium-intracellulare infection had bitemporal visual field defects that suggested optic chiasm damage.
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Arrhythmias and cardiac arrest have been reported during amphotericin B administration but no effective technique has been described to prevent them.
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BACKGROUND: In patients after treatment for malignant brain tumors, a clear distinction between tumor recurrence and radiation necrosis can be challenging.
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Despite the complicated drug regimen with which the patient was treated, tobramycin was implicated by rechallenge with the drug once before its role was understood and again at an outside hospital.
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Many patients who were on chronic TPN with MVI ceased to receive the MVI and were converted to an oral form of the multivitamin.
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After two months of therapy, repeat echocardiography showed complete resolution of the thrombus.
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An inverse correlation was found between plasma potassium and doses of phosphate (plasma potassium = -0.2 g phosphate + 3.9 r = -0.49; p < 0.05; N = 21).
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Seven years later, after chemotherapy with chlorambucil, chronic myelogenous leukemia was diagnosed in addition to the chronic lymphocytic leukemia.
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It has been reported that fluoroquinolone antimicrobials prolong the corrected QT interval but rarely cause torsade de pointes.
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Bone marrow chromosomes were studied in 2 patients with polycythaemia vera (PV) at the time of diagnosis and several times subsequently during therapy with chlorambucil.
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It is used worldwide not only as a cosmetic agent to stain the hair, skin and nails but also is applied to the body on lesions in the treatment of seborrheic dermatitis or fungal infections.
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Clonazepam was given as needed, and the patient was discharged on February 1 with myoclonus that soon subsided.
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Acetylsalicylic acid enhances both minor and major bleedings.
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BACKGROUND: Delivery of tobramycin by inhalation to the lungs of patients with cystic fibrosis (CF) who are infected with Pseudomonas aeruginosa has been proven to be effective and safe.
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The authors report a case of focal myocardial necrosis, presenting clinically as an acute myocardial infarction during the administration of the antineoplastic drug, amsacrine, in a patient without coronary artery disease.
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METHOD: The case histories of two geriatric patients treated with bupropion for major depression are presented.
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The shunt infection of the second patient was treated by replacement of the infected shunt system with a rifampin-impregnated device.
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CONCLUSIONS: The authors suggest that conventional treatments be limited to a 2-month period, and that alcohol neurolysis be applied as soon as possible to prevent lengthy pain experiences.
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An 8-year-old girl, who had been vaccinated with BCG without subsequent regional reactions, developed osteomyelitis in the left calcaneus 7 months later.
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New onset of CD may be considered as an immune-mediated injury induced by etanercept.
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Polymyositis is a rare complication of interferon alpha treatment as a result of immune-modulating role of the drug itself.
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Two of these cases concerned relatively young, previously healthy patients and had fatal outcomes.
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It is characterized by severe muscular rigidity, hyperthermia, and autonomic disturbances.
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Although PWO is often easily managed with small doses of thrombolytic therapy (e.g., urokinase), it could result in a more serious complication, such as chemotherapy extravasation.
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In conclusion, this case is instructive, because the symptoms which developed after a short period of corticosteroid inhalation suggested a type I allergy.
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The dose of fluorouracil in the second cycle was increased to 400 mg/m(2)/d continuous infusion over 5 days.
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Dihydropyrimidine dehydrogenase deficiency: a pharmacogenetic defect causing severe adverse reactions to 5-fluorouracil-based chemotherapy.
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It is generally accepted that corticosteroid therapy may increase weight.
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Diffuse cutaneous leishmaniasis (DCL) is a rare anergic variant of leishmanial infection with the characteristic presentation of numerous nonulcerating nodules with an abundant parasite load, lack of visceral involvement, negative reaction to the leishmanin skin test, and a chronic course with incomplete response to treatment and frequent relapses.
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Sulfasalazine-induced lung disorder is an extremely rare entity which must be considered in all ulcerative colitis patients while on sulfasalazine therapy, despite the absence of pulmonary symptomatology.
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Death from inappropriate therapy for Lyme disease.
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Except for the cellular membranes, each eye was without evidence of inflammation or cystoid macular edema.
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Combination therapy for psoriasis with methotrexate and etretinate.
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We report a case of hyponatremic seizures in a 7-year old boy with spina bifida following cystoscopy and suprapubic catheter placement.
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METHODS: Between April 2002 and October 2003, we performed 24 liver transplants in 25 patients.
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Addition of lithium carbonate resulted in a sustained remission with maintenance treatments.
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A change in government program policies caused him to receive generic carbamazepine.
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Severe osteomalacia was present in two epileptic patients who were under long-term treatment with congeners of phenytoin, phenobarbital, and acetazolamide.
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During FAB-treatment total DGTX serum concentrations and renal DGTX clearance rose, indicating redistribution of drug from tissue to serum and urinary elimination of FAB-bound DGTX, respectively.
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Patients with Crohn's disease may have reduced absorption in the small bowel due to loss of effective surface area secondary to chronic inflammation, ulcerative lesions, or resection.
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The authors report a case of acute pancreatitis (AP) occurring in a patient under treatment with carbamazepine (CBZ) for post-traumatic petit mal epilepsy, and review the current literature of drug-induced AP.
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On the fifth day of tocolysis with magnesium sulfate, nifedipine, terbutaline and betamethasone, edema developed in both labia.
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Partial response to antipsychotic treatment: the patient with enduring symptoms.
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The disease rapidly evolved into acute leukemia within 1 month after the onset of MDS, and the patient died 1 month later during induction chemotherapy.
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In addition, a 31-year-old man with obsessive-compulsive disorder developed RBD soon after starting fluoxetine therapy, which persisted at PSG study 19 months after fluoxetine discontinuation.
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Systemic lupus erythematosus and acute pancreatitis: a case series.
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Responsibility for the provision and use of these inhalers in young people is discussed and suggestions made towards their greater control.
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The patient and her parents underwent molecular analysis of the CYP2C19 gene, which may be implicated in the metabolism of this drug.
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Circulating anticoagulant in the procainamide-induced lupus syndrome.
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The possible mechanisms of this leukopenia are discussed.
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After two months of mechanical ventilation, the patient was stabilized.
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Changes in mood, personality, and social function were examined in a group of five Type 1 diabetic patients, aged 50 to 66 years, with duration of diabetes from 24 to 47 years.
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In each of the three reported patients, alteration of eyelid appearance with deepening of the lid sulcus was evident as the result of topical bimatoprost therapy.
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DGTX concentrations were determined after protein precipitation (release of FAB-bound and protein-bound DGTX) in unprocessed serum and urine samples, and after aliquots of these samples had been dialysed in vitro against DGTX-free buffer (elimination of DGTX not bound to FAB).
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REVIEW SUMMARY: In this review, I summarize the newest approved medications for the treatment of PD, including the new dopamine agonists and catechol-O-methyl-transferase inhibitors.
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Local dense accumulations of skin debris that became crusty were also observed.
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