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Paula Aristizabal|Jenelle Singer|Renee Cooper|Kristen J. Wells|Jesse Nodora|Mehrzad Milburn|Sheila Gahagan|Deborah Schiff|Mar??a Elena Mart??nez
Participation in pediatric oncology research protocols: Racial/ethnic, language and age?based disparities
2,015
University of California, San Diego|Rady Children's Hospital-San Diego|University of California, San Diego|San Diego State University|San Diego State University|University of California, San Diego|University of California, San Diego|University of California, San Diego|University of California, San Diego|Rady Children's Hospital-San Diego|University of California, San Diego|Rady Children's Hospital-San Diego|University of California, San Diego
background survival rates pediatric oncology improved dramatically part due high patient participation clinical trials although racialethnic inequalities clinical trial participation reported adults pediatric data studies comparing participation rates sociodemographic characteristics scarce goal study assess differences research protocol participation childhood cancer age sex raceethnicity parental language cancer type insurance status procedure data enrollment protocol biospecimen therapeutic protocols collected analyzed newly diagnosed pediatric patients cancer 20082012 rady childrens hospital results among 353 patients included analysis 304 861 enrolled protocol enrollment biospecimen therapeutic protocols 842 261310 811 206254 respectively logistic regression analyzes revealed significant enrollment underrepresentation protocol hispanics compared nonhispanic whites 81 vs 91 odds ratio 043 95 confidence interval ci 021090 p 0021 among children spanishspeaking vs englishspeaking parents 78 vs 89 045 95ci 023087 p 0016 compared patients aged 04 years significant underrepresentation also found among patients 1521 years old 92 vs72 021 95 ci 009048 p lt 0001 similar trends observed analyzing enrollment biospecimen therapeutic protocols separately conclusions significant underrepresentation protocol participation hispanics children spanishspeaking parents patients ages 1521 research needed understand barriers research participation among groups underrepresented pediatric oncology clinical trials pediatr blood cancer 20156213371344 2015 wiley periodicals inc
https://doi.org/10.7717/peerj.5251
Sneha Anil Kumar Vaidhyam|Kuo-Ting Huang
Social Determinants of Health and Patients’ Technology Acceptance of Telehealth During the COVID-19 Pandemic: Pilot Survey
2,023
University of Pittsburgh|University of Pittsburgh
background telehealth widely adopted patients covid19 pandemic many social determinants health influence adoption objective pilot study aimed understand social determinants patients adoption telehealth context pandemic methods survey methodology used capture data 215 participants using amazon mechanical turk study guided technology acceptance model social determinants health framework questionnaire included technology acceptance model variables eg perceived usefulness pu perceived ease use peou social determinants eg access health care socioeconomic status education health literacy demographic information eg age sex race ethnicity series ordinary least squares regressions conducted analyze data using spss statistics ibm corp results results showed social determinant factorssafe neighborhood built environment p01 economic stability p05are predictors peou telehealth adoption statistically significant marginally statistically significant level furthermore moderated mediation model process model 85 used analyze effects covid19 neighborhood built environment economic stability peou pu significantly positively affected users intention use technology variables conclusions study draws attention 2 research frameworks address unequal access health technologies also adds empirical evidence telehealth research adoption patient technology finally regarding practical implications study provide government agencies health care organizations health care companies better perspective patients digital health use guide designing better technology considering factors social determinants health
https://doi.org/10.2196/19056
Sachiko M. Oshima|Sarah Tait|Samantha M. Thomas|Oluwadamilola M. Fayanju|Kearston L. Ingraham|Nadine J. Barrett|E. Shelley Hwang
Association of Smartphone Ownership and Internet Use With Markers of Health Literacy and Access: Cross-sectional Survey Study of Perspectives From Project PLACE (Population Level Approaches to Cancer Elimination)
2,021
Duke University|Duke University|Duke University|Duke University|Duke University|Duke University
background telehealth increasingly important component health care delivery response covid19 pandemic however welldocumented disparities persist use digital technologies objective study aims describe smartphone internet use within diverse sample assess association smartphone internet use markers health literacy health access identify mediating factors relationships methods surveys distributed targeted sample designed oversample historically underserved communities april 2017 december 2017 multivariate logistic regression used estimate association internet smartphone use outcomes describing health care access markers health literacy total cohort stratifying personal history cancer health care access captured using multiple variables including ability obtain medical care needed markers health literacy included selfreported confidence obtaining health information results 2149 participants 1319 6138 women 655 3048 nonhispanic white 666 3099 nonhispanic black median age 51 years iqr 3865 respondents reported using internet 19212149 8939 owning smartphone 18002149 8376 compared respondents smartphone internet access without smartphone internet access likely report doctor recent source health information 3441800 1911 vs 116349 332 smartphone 3801921 1978 vs 80228 351 internet respectively plt001 internet use associated looked information health topics source odds ratio 381 95 ci 253575 confidence obtaining health information needed 183 95 ci 100334 compared noninternet users smartphone owners lower odds unable obtain needed medical care 062 95 ci 040095 nonsmartphone owners among participants prior history cancer smartphone ownership significantly associated higher odds confidence ability obtain needed health information 563 95 ci 1053023 lower odds inability obtain needed medical care 017 95 ci 006047 although associations significant among participants without prior history cancer conclusions describe widespread use digital technologies communitybased cohort although disparities persist cohort smartphone ownership significantly associated ability obtain needed medical care suggesting use smartphone technology may play role increasing health care access similarly major illnesses cancer potential amplify health engagement finally special emphasis must placed reaching patient populations limited digital access patients disadvantaged new age telehealth
https://doi.org/10.1016/s1470-2045(18)30648-x
Sarah Eichler|Annett Salzwedel|Sophie Rabe|Steffen Mueller|Frank Mayer|Monique Wochatz|Miralem Hadzic|Mathias John|Karl Wegscheider|Heinz Völler
The Effectiveness of Telerehabilitation as a Supplement to Rehabilitation in Patients After Total Knee or Hip Replacement: Randomized Controlled Trial
2,019
University of Potsdam|University of Potsdam|University of Potsdam|Trier University of Applied Sciences|University of Potsdam|University of Potsdam|University of Potsdam|Fraunhofer Institute for Open Communication Systems|University Medical Center Hamburg-Eppendorf|Universität Hamburg|University of Potsdam
background telerehabilitation contribute maintenance successful rehabilitation regardless location time aim study investigate specific threemonth interactive telerehabilitation routine regarding effectiveness assisting patients physical functionality returning work compared typical aftercare objective aim study investigate specific threemonth interactive telerehabilitation regard effectiveness functioning return work compared usual aftercare methods august 2016 december 2017 111 patients mean 549 years old sd 68 543 female hip knee replacement enrolled randomized controlled trial discharge inpatient rehabilitation three months distance 6minute walk test assessed primary endpoint functional parameters including health related quality life pain time return work secondary endpoints results patients intervention group performed telerehabilitation average 550 minutes sd 92 per week adherence high 75 7th week threemonth intervention phase almost patients therapists used communication options intervention group average difference 883 sd 577 p95 control group average difference 796 sd 487 p95 increased distance 6minutewalktest improvements functional parameters well quality life pain achieved groups higher proportion working patients intervention group 646 p01 versus control group 462 note conclusions effect investigated telerehabilitation therapy patients following knee hip replacement equivalent usual aftercare terms functional testing quality life pain since significantly higher returntowork rate could achieved therapy might promising supplement established aftercare trial registration german clinical trials register drks00010009 httpswwwdrksdedrkswebnavigatedo navigationidtrialhtmlamptrialiddrks00010009
https://doi.org/10.1093/heapol/czm027
Lyndsay A. Nelson|Andrew J. Spieker|Robert A. Greevy|Lauren M. LeStourgeon|Kenneth A. Wallston|Lindsay S. Mayberry
User Engagement Among Diverse Adults in a 12-Month Text Message–Delivered Diabetes Support Intervention: Results from a Randomized Controlled Trial
2,020
Vanderbilt University Medical Center|Vanderbilt University Medical Center|Vanderbilt University Medical Center|Vanderbilt University Medical Center|Vanderbilt University Medical Center|Vanderbilt University Medical Center
background text messagedelivered interventions feasible scalable approach improving chronic disease selfcare reducing health disparities however information longterm user engagement interventions limited objective aim study examine user engagement 12month text messagedelivered intervention supporting diabetes selfcare called reach rapid educationencouragement communications health among racially socioeconomically diverse patients type 2 diabetes t2d explored time trends engagement associations patient characteristics engagement whether addition human component allowing patients change text frequency affected engagement qualitative data informed patients subjective experience engagement methods recruited patients t2d randomized trial evaluating mobile phone support relative enhanced treatment usual analysis limited participants assigned intervention participants completed survey hemoglobin a1c hba1c test received reach text messages including selfcare promotion texts interactive texts asking medication adherence adherence feedback texts first 6 months texts sent daily half participants also received monthly phone coaching 6 months coaching stopped participants option receive fewer texts subsequent 6 months defined engagement via responses interactive texts responses followup interview used regression models analyze associations response rate thematic structural analysis understand participants reasons responding texts preferred text frequency results participants average aged 558 sd 98 years 552 137248 female 520 129248 nonwhite 407 101248 high school education 407 101248 annual household income ltus 25000 median response rate interactive texts 91 iqr 7597 12 months engagement gradually declined throughout intervention remained high engagement differ age gender education income diabetes duration insulin status health literacy numeracy black race worse baseline medication adherence hba1c associated lower engagement although effects small nearly half participants chose continue receiving daily texts last 6 months intervention participants continued daily text messages said wanted continue experiencing benefits health whereas chose fewer texts said daily texts helped create routines longer needed often engagement impacted receiving coaching participants chosen text frequency conclusions welldesigned interactive text messages engage diverse patients selfcare intervention least 1 year variation reasons frequency preference suggest offering frequency choice may important users engagement
https://doi.org/10.7717/peerj.3744
Lee Goldman|Philip Chu|H??ng Thanh Tr?n|Max J. Romano|Randall S. Stafford
Federally Qualified Health Centers and Private Practice Performance on Ambulatory Care Measures
2,012
University of California, San Francisco|University of California, San Francisco|University of California, San Francisco|Johns Hopkins University|Johns Hopkins Medicine|Stanford University
background 2010 affordable care act relies federally qualified health centers fqhcs fqhc lookalikes lookalikes provide care newly insured patients ties increased funding demonstrated quality efficiency purpose compare fqhc lookalike physician performance private practice primary care physicians pcps ambulatory care quality measures methods study crosssectional analysis visits 20062008 national ambulatory medical care survey performance fqhcs lookalikes 18 quality measures compared private practice pcps data analysis completed 2011 results compared private practice pcps fqhcs lookalikes performed better six measures p005 worse diet counseling atrisk adolescents 26 vs 36 p005 differently 11 measures higher performance occurred ace inhibitors use congestive heart failure 51 vs 37 p0004 aspirin use coronary artery disease cad 57 vs 44 p0004 blocker use cad 59 vs 47 p001 use benzodiazepines depression 91 vs 84 p0008 blood pressure screening 90 vs 86 p0001 screening electrocardiogram ekg avoidance lowrisk patients 99 vs 93 p0001 adjusting patient characteristics yielded similar results except private practice pcps longer performed better measures conclusions fqhcs lookalikes demonstrated equal better performance private practice pcps select quality measures despite serving patients chronic disease socioeconomic complexity findings provide policymakers reassurance quality chronic disease preventive care federally qualified health centers lookalikes plan use health centers serve 20 million newly insured individuals 2010 affordable care act relies federally qualified health centers fqhcs fqhc lookalikes lookalikes provide care newly insured patients ties increased funding demonstrated quality efficiency compare fqhc lookalike physician performance private practice primary care physicians pcps ambulatory care quality measures study crosssectional analysis visits 20062008 national ambulatory medical care survey performance fqhcs lookalikes 18 quality measures compared private practice pcps data analysis completed 2011 compared private practice pcps fqhcs lookalikes performed better six measures p005 worse diet counseling atrisk adolescents 26 vs 36 p005 differently 11 measures higher performance occurred ace inhibitors use congestive heart failure 51 vs 37 p0004 aspirin use coronary artery disease cad 57 vs 44 p0004 blocker use cad 59 vs 47 p001 use benzodiazepines depression 91 vs 84 p0008 blood pressure screening 90 vs 86 p0001 screening electrocardiogram ekg avoidance lowrisk patients 99 vs 93 p0001 adjusting patient characteristics yielded similar results except private practice pcps longer performed better measures fqhcs lookalikes demonstrated equal better performance private practice pcps select quality measures despite serving patients chronic disease socioeconomic complexity findings provide policymakers reassurance quality chronic disease preventive care federally qualified health centers lookalikes plan use health centers serve 20 million newly insured individuals
https://doi.org/10.1002/14651858.cd005537.pub2
Saul S. Morris|Robert E. Black|Lana Tomaškovi?
Predicting the distribution of under-five deaths by cause in countries without adequate vital registration systems
2,003
London School of Hygiene & Tropical Medicine
background absence complete vital registration atypical nature locations epidemiological studies cause death children conducted make difficult know true distribution child deaths cause developing countries credible method needed generating valid estimates distribution countries without adequate vital registration systems methods systematic review undertaken studies published since 1980 reporting under5 mortality cause causes death standardized across studies information collected characteristics study population metaregression model used relate characteristics various proportional mortality outcomes predict distribution national populations known characteristics 46 studies met inclusion criteria results proportional mortality outcomes significantly associated region mortality level exposure malaria coverage measles vaccination safe delivery care safe water study year age children surveillance method used establish definitive cause death subsaharan africa south asia predicted distribution deaths cause pneumonia 23 23 malaria 24 1 diarrhoea 22 23 neonatal 29 52 measles 2 1 conclusions countries without adequate vital registration possible estimate proportional distribution child deaths cause exploiting systematic associations distribution characteristics populations studied controlling design features studies
https://doi.org/10.1080/08897077.2017.1375061
Eric Maimela|Marianne Alberts|S. E. P. Modjadji|Solomon Choma|Sekgothe Dikotope|Thembelihle Sam Ntuli|Jean?Pierre Van Geertruyden
The Prevalence and Determinants of Chronic Non-Communicable Disease Risk Factors amongst Adults in the Dikgale Health Demographic and Surveillance System (HDSS) Site, Limpopo Province of South Africa
2,016
University of Antwerp|University of Limpopo|University of Limpopo|University of Limpopo|University of Limpopo|University of Limpopo|University of Limpopo|University of Antwerp
background aim study determine prevalence determinants chronic noncommunicable disease ncd risk factors rural community limpopo province south africa methods survey conducted using stepwise approach surveillance noncommunicable diseases steps methodology participants residents dikgale hdss site standardised international protocols used measure behavioural risk factors smoking alcohol consumption fruit vegetable intake physical activity physical characteristics weight height waist hip circumferences blood pressurebp fasting blood glucose triglyceride cholesterol hdlc determined 732 participants data analysed using stata 12 windows results prevalence current smokers amongst participants 137 813 daily smokers alcohol consumed 163 participants majority participants 886 low daily intake fruit vegetables low physical activity 665 prevalence hypertension amongst participants 382 overweight obesity high waist circumference prevalent females cardiometabolic risk profile significantly different men women people older 40 years overweight obese consumed alcohol likely hypertensive smoking associated significantly older age males never married divorced people alcohol consumption associated older age males low educational status low income conclusion high levels risk factors ncds among adults dikgale hdss suggest urgent need health interventions control risk factors population level order reduce prevalence ncds
https://doi.org/10.12659/msm.902639
Jennifer L. Steel|David A. Geller|Kevin H. Kim|Lisa H. Butterfield|Michael B. Spring|Jonathan Grady|Weiing Sun|Wallis Marsh|Michael H. Antoni|Mary Amanda Dew|Vicki S. Helgeson|Richard Schulz|Allan Tsung
<scp>W</scp>eb?based collaborative care intervention to manage cancer?related symptoms in the palliative care setting
2,016
University of Pittsburgh|University of Pittsburgh|University of Pittsburgh|UPMC Hillman Cancer Center|University of Pittsburgh|University of Pittsburgh|UPMC Hillman Cancer Center|University of Pittsburgh|Sylvester Comprehensive Cancer Center|University of Miami|University of Pittsburgh|Carnegie Mellon University|University of Pittsburgh|University of Pittsburgh
background aim study examine efficacy collaborative care intervention reducing depression pain fatigue improve quality life methods total 261 patients advanced cancer 179 family caregivers randomized webbased collaborative care intervention enhanced usual care intervention included following 1 web site written audiovisual selfmanagement strategies bulletin board resources 2 visits care coordinator physicians appointment every 2 months 3 telephone followup every 2 weeks primary patient outcomes included measures depression pain fatigue healthrelated quality life secondary outcomes included interleukin il1 il1 il6 il8 levels natural killer nk cell numbers caregiver stress depression results baseline 51 patients reported 1 symptoms clinical range patients presented clinical levels symptoms randomized intervention reductions depression cohens 071 pain cohens 062 fatigue cohens 026 improvements quality life cohens 099 observed compared enhanced usual car arm 6 months reductions il6 018 il1 035 il1 019 il8 015 increases nk cell numbers 023 observed comparison enhanced usual care arm 6 months reductions caregiver stress cohens 075 depression cohens 037 observed 6 months caregivers whose loved ones randomized intervention arm conclusions integration screening symptom management cancer care recommended cancer 2016122127082 2016 american cancer society
https://doi.org/10.1002/cncr.30481
Terry C. Davis|Connie L. Arnold|Alfred Rademaker|Charles L. Bennett|Stacy Cooper Bailey|Daci Platt|Cristalyn Reynolds|Dachao Liu|Edson Carias|Pat F. Bass|Michael S. Wolf
Improving colon cancer screening in community clinics
2,013
Louisiana State University Health Sciences Center Shreveport|Louisiana State University Health Sciences Center Shreveport|Northwestern University|MUSC Hollings Cancer Center|Medical University of South Carolina|University of North Carolina at Chapel Hill|Louisiana State University Health Sciences Center Shreveport|Louisiana State University Health Sciences Center Shreveport|Northwestern University|Northwestern University|Louisiana State University Health Sciences Center Shreveport|Northwestern University
background authors evaluated effectiveness cost effectiveness 2 interventions designed promote colorectal cancer crc screening safetynet settings methods 3arm quasiexperimental evaluation conducted among 8 clinics louisiana screening efforts included 1 enhanced usual care 2 literacyinformed education patients 3 education plus nurse support overall 961 averagerisk patients ages 50 85 years eligible routine crc screening recruited outcomes included crc screening completion incremental cost effectiveness using literacyinformed education patients education plus nurse support versus enhanced usual care results baseline screening rate lt3 interventions screening rate 386 enhanced usual care 571 education 606 education included additional nurse support adjusting age race sex literacy patients received education alone likely complete screening received enhanced usual care received additional nurse support 160fold likely complete screening received enhanced usual care 95 confidence interval 106242 p 024 incremental cost per additional individual screened 1337 education plus nurse support enhanced usual care conclusions fecal occult blood test rates increased beyond enhanced usual care providing brief education nurse support providing education alone costeffective alternatives nurse support need investigated cancer 201311938793886 2013 american cancer society
https://doi.org/10.1002/cncr.28970
TusaRebecca E. Pannucci|Frances E. Thompson|Regan L Bailey|Kevin W. Dodd|Nancy Potischman|Sharon I. Kirkpatrick|Gwen Alexander|Laura Coleman|Lawrence H. Kushi|Michelle Groesbeck|Maria E. Sundaram|Heather Clancy|Stephanie M. George|Lisa Kahle|Amy F. Subar
Comparing Reported Dietary Supplement Intakes between Two 24-Hour Recall Methods: The Automated Self-Administered 24-Hour Dietary Assessment Tool and the Interview-Administered Automated Multiple Pass Method
2,018
null
background automated selfadministered 24hour dietary assessment tool asa24 includes highly standardized multipass webbased recall like automated multiple pass method ampm captures detailed information dietary intake using multiple probes reminders enhance recall intakes primary distinction asa24 ampm asa24 user interface guides participants thus removing need interviewers objective objective study compare dietary supplement use reported selfadministered asa242011 vs intervieweradministered ampm 24hour recalls design food reporting comparison study evaluation study designed compare selfreported intakes captured using selfadministered asa24 vs data collected via intervieweradministered ampm recalls 2010 2011 1081 women men enrolled three integrated health care systems belong national cancer institutefunded cancer research network security health plan marshfield clinic wisconsin henry ford health system michigan kaiser permanente northern california california quota sampling used ensure balance age sex raceethnicity participants randomly assigned four groups group asked complete two dietary recalls group 1 two asa24s group 2 two ampms group 3 asa24 first ampm second group 4 ampm first asa24 second dietary supplements coded using 20072008 national health nutrition examination survey dietary supplement database analyses used two onesided tests known tost assess equivalence reported supplement use methods results complete 24hour dietary recalls included dietary supplement intake data available 1076 participants 507 men 569 women proportions reporting supplement use via asa24 ampm 46 43 respectively proportions equivalent small effect size less 20 two exceptions subgroup analyses reported use among 40 59 years age reported use nonhispanic black subjects higher asa24 ampm conclusions study provides evidence little difference reported supplement use mode administration ie interviewadministered vs selfadministered recall
https://doi.org/10.1002/1097-0142(20011115)92:10<2673::aid-cncr1621>3.0.co;2-2
Brian A. Primack|Auden C. McClure|Zhigang Li|James D. Sargent
Receptivity to and Recall of Alcohol Brand Appearances in U.S. Popular Music and Alcohol-Related Behaviors
2,014
University of Pittsburgh|Dartmouth College|Cotton (United States)|Cotton (United States)|Dartmouth College|Cotton (United States)
background average us adolescent exposed 25 hours popular music 8 mentions alcohol brands every day alcohol brand mentions may function advertising whether sanctioned alcohol industry study aimed determine associations adolescents involvement music containing alcohol brand mentions alcoholrelated behaviors methods 2010 2011 conducted randomdigitdial survey using national us land line cell phone frames screening interviews identified 6466 eligible households subjects 15 23 years age 3422 53 completed telephone survey 2541 opted participate subsequent webbased component independent variables included composite score indicating owning liking popular songs alcohol brand mentions correct recall alcohol brands songs outcome measures included ever consumed complete drink ever bingeing bingeing least monthly experienced problems alcohol use results among 2541 participants compared lowest tertile receptivity scale highest tertile higher odds complete drink 34 95 ci 22 52 adjusting age sex raceethnicity socioeconomic status sensation seeking friend alcohol use parent alcohol use compared identify least 1 alcohol brand correctly twice odds complete drink 21 95 ci 12 38 adjusting covariates results also significant outcome ever bingeing bingeing least monthly problems due drinking conclusions national sample us adolescents young adults independent associations involvement popular music containing alcohol brand mentions ever complete drink ever binged alcohol
https://doi.org/10.1002/da.20911
Leah L. Zullig|Ryan Shaw|Matthew J. Crowley|Jennifer H. Lindquist|Steven C. Grambow|Eric D. Peterson|Bimal R. Shah|Hayden B. Bosworth
Association Between Perceived Life Chaos and Medication Adherence in a Postmyocardial Infarction Population
2,013
Duke University|Clinical Research Institute|Durham VA Medical Center|Duke University|Clinical Research Institute|Durham VA Medical Center|Duke University|Clinical Research Institute|Duke University|Clinical Research Institute|Durham VA Medical Center|Duke University|Clinical Research Institute|Durham VA Medical Center|Duke University|Clinical Research Institute|Duke University|Clinical Research Institute|Duke University|Clinical Research Institute
background benefits medication adherence control cardiovascular disease cvd well defined yet multiple studies identified poor adherence influence life chaos medication adherence unknown novel application instrument preliminary objective understand patient factors associated chaos main objective evaluate extent instrument designed measure life chaos associated cvdmedication nonadherence methods results using baseline data ongoing randomized trial improve postmyocardial infarction mi management multivariable logistic regression identified association life chaos cvdmedication nonadherence patients hypertension myocardial infarction past 3 years n406 nearly 43 reported cvdmedication nonadherence past month simple linear regression following associated higher life chaos medication nonadherence 186 95 confidence interval ci 096276 female sex 122 95 ci 022224 minority race 172 95 ci 078266 less high school education 205 95 ci 071339 low health literacy 206 95 ci 086326 inadequate financial status 193 95 ci 087300 married 209 95 ci 303 115 associated lower life chaos chaos quartile increased patients exhibited nonadherence logistic regression adjusting sex race marital status employment education health literacy financial status 1unit life chaos increase associated 7 increase odds ratio 107 95 ci 102112 odds reporting medication nonadherence conclusions results suggest life chaos may important determinant medication adherence life chaos screenings could identify risk nonadherence clinical trial registration url httpwwwclinicaltrialsgov unique identifier nct000901277
https://doi.org/10.3389/fpsyg.2023.1246996
Tatiana Toro?Ramos|Andreas Michaelides|Maria Anton|Zulekha Karim|Leah Kang-Oh|Charalambos Argyrou|Elisavet Loukaidou|Marina Charitou|Wilson Sze|Joshua D. Miller
Mobile Delivery of the Diabetes Prevention Program in People With Prediabetes: Randomized Controlled Trial
2,020
Noom (United States)|Noom (United States)|Stony Brook School|Stony Brook University|Stony Brook School|Stony Brook University|Stony Brook School|Stony Brook University|Stony Brook School|Stony Brook University|Stony Brook School|Stony Brook University|Stony Brook School|Stony Brook University|Stony Brook School|Stony Brook University|Stony Brook School|Stony Brook University
background centers disease control prevention cdc diabetes prevention program dpp formed foundation type 2 diabetes mellitus t2dm prevention efforts lifestyle change modifications multiple care settings knowledge randomized controlled trial verified efficacy fully mobile version cdcs diabetes prevention program dpp objective study aimed investigate longterm weight loss glycemic efficacy mobiledelivered dpp compared control group receiving usual medical care methods adults prediabetes n202 recruited clinic randomized either mobiledelivered coachguided dpp noom control group received regular medical care including paperbased dpp curriculum formal intervention intervention group learned use noom program interact coach importance maintaining motivation access interactive coachtoparticipant interface group messaging daily challenges behavior change dppbased education articles food logging automated feedback primary outcomes included changes weight hemoglobin a1c hba1c levels 6 12 months respectively exploratory secondary outcomes included program engagement predictor changes weight hba1c levels results total 202 participants recruited randomized intervention n101 control group n99 intentiontotreat itt analyses changes participants weight bmi significantly different 6 months intervention control groups difference hba1c levels mean difference 0004 se 005 p94 weight bmi lower intervention group 264 kg se 071 plt001 099 kgm2 se 029 p001 respectively differences persisted 12 months however analyses involve itt program completers achieved significant weight loss 56 se 081 plt001 6 months maintaining 47 se 088 plt001 weight loss 12 months control group lost 015 6 months se 064 p85 gained 033 se 070 p63 12 months randomized intervention group start program meaningful weight hba1c level change similar control group 1 year intervention group showed 023 reduction hba1c levels completed intervention showed 028 reduction assigned control group 016 reduction hba1c levels conclusions novel mobiledelivered dpp achieved significant weight loss reductions 1 year compared usual care type intervention reduces risk overt diabetes without added barriers inperson interventions trial registration clinicaltrialsgov nct03865342 httpsclinicaltrialsgovct2shownct03865342
https://doi.org/10.1371/journal.pone.0204091
Helen Frost|Pauline Campbell|Margaret Maxwell|Ronan E. O’Carroll|Stephan U Dombrowski|Brian Williams|Helen Cheyne|Emma Coles|Alex Pollock
Effectiveness of Motivational Interviewing on adult behaviour change in health and social care settings: A systematic review of reviews
2,018
Edinburgh Napier University|Glasgow Caledonian University|University of Stirling|University of Stirling|University of Stirling|Edinburgh Napier University|University of Stirling|University of Stirling|Glasgow Caledonian University
background challenge addressing unhealthy lifestyle choice global concern motivational interviewing widely implemented help people change behaviour unclear beneficial overview aims appraise synthesise review evidence effectiveness motivational interviewing health behaviour adults health social care settings methods systematic review reviews methods prespecified documented protocol prosperocrd42016049278 systematically searched 7 electronic databases cdsr dare prospero medline cinahl amed psycinfo 2000 may 2018 two reviewers applied predefined selection criteria extracted data using tidier guidelines assessed methodological quality using robis tool used grade criteria rate strength evidence reviews including metaanalyses findings searches identified 5222 records one hundred four reviews including 39 metaanalyses met inclusion criteria metaanalysis evidence graded low low 128155 moderate quality evidence mainly short term 6 months statistically significant small beneficial effects motivational interviewing found 11 155 7 metaanalysis comparisons outcomes include reducing binge drinking frequency quantity alcohol consumption substance abuse people dependency addiction increasing physical activity participation conclusions created comprehensive map reviews relating motivational interviewing signpost stakeholders best available evidence high quality research needed confident effectiveness motivational interviewing identified large volume low quality evidence many areas overlapping research avoid research waste vital researchers aware existing research implications arising research case motivational interviewing issues relating monitoring reporting fidelity interventions need addressed
https://doi.org/10.1371/journal.pone.0181074
Aart van Stekelenburg|Gabi Schaap|Harm Veling|Moniek Buijzen
Investigating and Improving the Accuracy of US Citizens’ Beliefs About the COVID-19 Pandemic: Longitudinal Survey Study
2,021
Radboud University Nijmegen|Radboud University Nijmegen|Radboud University Nijmegen|Erasmus University Rotterdam|Radboud University Nijmegen
background covid19 infodemic surge information misinformation sparked worry publics perception coronavirus pandemic excessive information misinformation lead belief false information well reduce accurate interpretation true information incorrect beliefs covid19 pandemic might lead behavior puts people risk contracting spreading virus objective objective study twofold first attempted gain insight public beliefs novel coronavirus covid19 one worst hit countries united states second aimed test whether short intervention could improve peoples belief accuracy empowering consider scientific consensus evaluating claims related pandemic methods conducted 4week longitudinal study among us citizens starting april 27 2020 daily covid19 deaths united states peaked week measured participants belief accuracy related coronavirus covid19 asking indicate extent believed number true false statements split 5050 furthermore new survey wave included original statements four new statements two false two true statements half participants exposed intervention aimed increasing belief accuracy intervention consisted short infographic set three steps verify information searching verifying scientific consensus results total 1202 us citizens balanced regarding age gender ethnicity approximate us general public completed baseline t0 wave survey retention rate followup waves first followup wave t1 second followup wave t2 final wave t3was high 85 mean scores belief accuracy high waves scores reflecting low belief false statements high belief true statements belief accuracy scale ranged 1 indicating completely inaccurate beliefs 1 indicating completely accurate beliefs t0 mean 075 t1 mean 078 t2 mean 077 t3 mean 075 accurate beliefs correlated selfreported behavior aimed preventing coronavirus spreading eg social distancing r waves 026 029 p values less 001 associated trust scientists ie higher trust associated accurate beliefs political orientation ie liberal democratic participants held accurate beliefs conservative republican participants primary news source ie participants reporting cnn fox news main news source held less accurate beliefs others intervention significantly improve belief accuracy conclusions supposed infodemic reflected us citizens beliefs covid19 pandemic people quite able figure facts relatively early days crisis calling question prevalence misinformation publics susceptibility misinformation
https://doi.org/10.2196/14802
Rosa Hernandez-Ramos|Adrián Aguilera|Faviola Garcia|Jose Miramontes|Laura Elizabeth Pathak|Caroline A. Figueroa|Courtney R. Lyles
Conducting Internet-Based Visits for Onboarding Populations With Limited Digital Literacy to an mHealth Intervention: Development of a Patient-Centered Approach
2,021
null
background covid19 pandemic propelled patientfacing research shift digital telehealth strategies strategies adapted minority patients lower socioeconomic status health inequality increase patientcentered models care successfully improve access experience minority patients objective study aims present development process preliminary acceptability altering inperson onboarding procedures internetbased remote procedures mobile health mhealth intervention population limited digital literacy methods actively recruited safetynet patients english spanishspeaking adults diabetes depression receiving care public health care delivery system san francisco united states randomized controlled trial text messaging support physical activity covid19 pandemic modified inperson recruitment onboarding procedures internetbased remote processes human support conducted preliminary evaluation composition recruited cohort might changed precovid19 period covid19 enrollment period first analyzed digital profiles patients n32 participated previous inperson onboarding sessions prior covid19 pandemic next documented changes made onboarding processes account remote recruitment especially needed support patients familiar downloading apps onto mobile phones finally used new study procedures recruit patients n11 covid19 social distancing period patients also asked experience enrolling fully digitized mhealth intervention results recruitment across precovid19 covid19 periods n43 demonstrated relatively high rates smartphone ownership lower selfreported digital literacy 326 1443 patients reporting needed help using smartphone installing apps significant changes made onboarding procedures including facilitating app download via zoom video call andor standard phone call implementing brief oneonone staffpatient interactions provide technical assistance personalized patients digital literacy skills comparing recruitment precovid19 covid19 periods proportion patients digital literacy barriers reduced 344 1132 precovid19 cohort 273 311 covid19 cohort differences digital literacy scores cohorts significant p49 conclusions patients lower socioeconomic status high interest using digital platforms manage health may require additional upfront human support gain access oneonone staffpatient partnerships allowed us provide unique technical assistance personalized patients digital literacy skills simple strategies troubleshoot patient barriers upfront additional remote onboarding strategies mitigate eliminate digital barriers patients without extensive technology experience trial registration clinicaltrialsgov nct0349025 httpsclinicaltrialsgovct2shownct03490253
https://doi.org/10.2196/14854
Getanew Aschalew Tesfa|Delelegn Emwodew Yehualashet|Helen Ali Ewune|Addisu Getnet Zemeskel|Mulugeta Hayelom Kalayou|Binyam Tariku Seboka
eHealth Literacy and its Associated Factors Among Health Professionals During the COVID-19 Pandemic in Resource-Limited Settings: Cross-sectional Study
2,022
Dilla University|Dilla University|Dilla University|Dilla University|Wollo University|Dilla University
background covid19 pandemic wreaked havoc health care systems governments worldwide although ehealth literacy acknowledged critical component public health overlooked pandemic assist patients families health professionals knowledgeable online health information resources capable evaluating relevant online information resourceconstrained situation level ehealth literacy among health professionals well documented objective aim study assess ehealth literacy level associated factors among health professionals working amhara regional state teaching hospitals ethiopia methods selfadministered questionnaire used institutionalbased crosssectional study design descriptive statistics calculated describe ehealth literacy statements key variables using spss v24 bivariable multivariable logistic regression models fit identify factors related ehealth literacy variables plt05 declared statistically significant predictors results total 383 participants completed returned questionnaire response rate 905 health professionals demonstrated moderate level ehealth literacy mean 2921 professionals aware available health resources located internet know search locate resources however lack ability distinguish highquality health resources lowquality resources factors significantly associated ehealth literacy computer access computer knowledge perceived ease use perceived usefulness ehealth information resources conclusions crucial provide training support health care workers find interpret importantly evaluate quality health information found internet improve ehealth literacy level research needed explore role ehealth literacy mitigating pandemics developing countries
https://doi.org/10.2196/17572
Rose C. Maly|Yihang Liu|Li?Jung Liang|Patricia A. Ganz
Quality of life over 5 years after a breast cancer diagnosis among low?income women: Effects of race/ethnicity and patient?physician communication
2,014
University of California, Los Angeles|University of California, Los Angeles|University of California, Los Angeles|University of California, Los Angeles|Los Angeles County Department of Health Services
background current study performed identify risk factors lower quality life qol among lowincome women breast cancer bc emphasis impact patientphysician communication addition ethnicracial group differences qol changes time examined methods longitudinal study conducted among 921 lowincome women bc patients interviewed 6 months 18 months 36 months 60 months diagnosis bc mixedeffect regression models performed investigate predictors time effects qol main outcomes included medical outcomes study health survey short form36 mental component summary scale sf36 mcs medical outcomes study health survey short form36 physical component summary scale sf36 pcs ladder life scale chief independent variables included physician informationgiving patient selfefficacy interacting physicians results significant changes noted time qol except regard physical functioning survivors reporting significant decrease time p lt0001 mean sf36 mcs sf36 pcs scores lower national general population norms time points patient selfefficacy interacting physicians physician informationgiving found positively associated sf36 mcs p 03 p 02 respectively ladder life p 01 p 03 respectively scales latinas less acculturated reported higher sf36 mcs sf36 pcs scores p lt0001 p 01 respectively better global qol p lt0001 white women conclusions lowincome women bc experienced poor physical mental health results current study suggest qol among lowincome women bc would enhanced interventions aimed empowering patients communicating physicians increasing amount information provided physicians cancer 2015121916926 2014 american cancer society
https://doi.org/10.1556/2006.6.2017.037
Jennifer E. Mersereau|Linnea R. Goodman|Allison M. Deal|Jessica R. Gorman|Brian W. Whitcomb|H. Irene Su
To preserve or not to preserve
2,013
University of North Carolina at Chapel Hill|University of North Carolina at Chapel Hill|University of North Carolina at Chapel Hill|University of California, San Diego|University of Massachusetts Amherst|University of California, San Diego
background decision pursue fertility preservation fp cancer diagnosis complex examined prevalence high decisional conflict specific factors influence decision using decisional conflict scale dcs methods first project webbased survey female cancer survivors ages 1844 years undergone gonadotoxic treatment evaluated association recalled decisional conflict referral fp counseling demographic socioeconomic cancer variables results 208 participants 115 subjects 55 scores consistent high decisional conflict dcs score gt375 100 43 21 moderate range 25375 unadjusted analysis high decisional conflict associated lack referral fp consultation undergoing fp treatment concerns regarding fp cost length survivorship lower income education partner status cancer type multivariable analysis significantly higher prevalence high decisional conflict observed participants referred fp consultation prevalence ratio pr 125 95 confidence interval ci 106147 well participants reported cost fp services prohibitive pr 116 95 ci 103131 prevalence high dcs lower women underwent fp treatment pr 067 95 ci 052086 conclusions study female young adult cancer survivors majority recalled significant decisional conflict fp cancer diagnosis increasing access fp via referral counseling cost reduction may decrease decisional conflict fp young patients struggling cancer fertility decisions cancer 2013 11940444050 2013 american cancer society
https://doi.org/10.1097/nnr.0000000000000389
Guy G. Potter|Brenda L. Plassman|James R. Burke|Mohammed U. Kabeto|Kenneth M. Langa|David J. Llewellyn|Mary A.M. Rogers|David C. Steffens
Cognitive performance and informant reports in the diagnosis of cognitive impairment and dementia in African Americans and whites
2,009
Duke University Hospital|Duke Medical Center|Duke University Hospital|Duke Medical Center|Duke University Hospital|Duke Medical Center|University of Michigan–Ann Arbor|University of Michigan–Ann Arbor|VA Center for Clinical Management Research|University of Cambridge|University of Michigan–Ann Arbor|Duke University Hospital|Duke Medical Center
background diagnosis cognitive impairment dementia must reflect increasingly diverse aging united states population study compared direct testing informant reports cognition clinical diagnoses cognitive impairment dementia african americans whites methods participants aging demographics memory study completed inperson dementia evaluations assigned clinical diagnoses consensus panel dementia experts normal cognitive impairment demented cind dementia consortium establish registry alzheimers disease cerad total score informant questionnaire cognitive decline elderly iqcode used assess cognitive performance reported cognitive decline results higher cerad total score associated lower odds cind dementia comparable ratios african americans whites higher iqcode scores associated increased odds dementia african americans whites higher iqcode scores associated increased odds cind among whites among african americans conclusions cultural differences may influence informant reports prevalent cind dementia findings also highlight need comparative research establish cultural validity measures used diagnose conditions
https://doi.org/10.1371/journal.pone.0198083
Diwakar Mohan|Jean Juste Harrisson Bashingwa|Nicki Tiffin|Diva Dhar|Nicola Mulder|Asha George|Amnesty LeFevre
Does having a mobile phone matter? Linking phone access among women to health in India: An exploratory analysis of the National Family Health Survey
2,020
Johns Hopkins University|University of Cape Town|Wellcome Centre for Infectious Diseases Research in Africa|University of Cape Town|University of Cape Town|University of the Western Cape|University of Cape Town|Johns Hopkins University
background disruptive potential mobile phones catalyzing development increasingly recognized however numerous gaps remain access phones influence health care utilization crosssectional study india assess gaps womens access phones influencing factors influence health care utilization methods data drawn 2015 national family health survey nfhs india included national sample 45231 women data phone access survey design weighted estimates household phone ownership womens access among different population subgroups presented multilevel logistic models explored association phone access wide range maternal child health indicators blinderoaxaca bo decomposition used decompose gaps women without phone access health care utilization components explained background characteristics influencing phone access endowments unexplained components coefficients potentially attributable phone access findings phone ownership household level 928 95 ci 926930 rural ownership 911 908914 urban 971 967973 womens access phones 478 467488 416 rural areas 405426 627 604648 urban phone access urban areas positively associated skilled birth attendance postnatal care use modern contraceptives negatively associated early antenatal care phone access associated improvements utilization indicators rural settings phone access coefficient components explained large gaps use modern contraceptives moderate gaps postnatal care early antenatal care smaller differences use skilled birth attendance immunization full antenatal car phone access associated reducing gaps utilization interpretation women reproductive age significantly lower phone access use households belong marginalized women least phone access existing phone access rural women improve health care utilization associated greater utilization urban women without addressing biases digital health programs may risk worsening existing health inequities
https://doi.org/10.2522/ptj.20120473
Renata W. Yen|Jenna Smith|Jaclyn Engel|Danielle M Muscat|Sian K Smith|Julien Mancini|Lilisbeth Perestelo?Pérez|Glyn Elwyn|A. James O’Malley|JoAnna K. Leyenaar|Olivia Mac|Tamara Cadet|Anik Giguère|Ashley J. Housten|Aisha T. Langford|Kirsten McCaffery|Marie?Anne Durand
A Systematic Review and Meta-Analysis of Patient Decision Aids for Socially Disadvantaged Populations: Update from the International Patient Decision Aid Standards (IDPAS)
2,021
Dartmouth Institute for Health Policy and Clinical Practice|Dartmouth College|University of Sydney|Dartmouth Institute for Health Policy and Clinical Practice|Dartmouth College|University of Sydney|University of Bath|Inserm|Economic & Social Sciences, Health Systems & Medical Informatics|Aix-Marseille University|Institut de Recherche pour le Développement|Servicio Canario de la Salud|Dartmouth Institute for Health Policy and Clinical Practice|Dartmouth College|Dartmouth Institute for Health Policy and Clinical Practice|Dartmouth College|Dartmouth Institute for Health Policy and Clinical Practice|Dartmouth College|Dartmouth–Hitchcock Medical Center|University of Sydney|Simmons University|Harvard University|Université Laval|Washington University in St. Louis|New York University|University of Sydney|Dartmouth Institute for Health Policy and Clinical Practice|Dartmouth College|Université Toulouse III - Paul Sabatier
background effectiveness patient decision aids ptdas shared decisionmaking sdm interventions socially disadvantaged populations well studied purpose assess whether ptdas sdm interventions improve outcomes decrease health inequalities among socially disadvantaged populations determine critical features successful interventions data sources medline cinahl cochrane psycinfo web science inception october 2019 cochrane systematic reviews ptdas study selection randomized controlled trials ptdas sdm interventions included socially disadvantaged populations data extraction independent double data extraction using standardized form template intervention description replication checklist data synthesis twentyfive ptda 13 sdm intervention trials met inclusion criteria compared usual care ptdas improved knowledge mean difference 1391 95 confidence interval ci 901 1882 2 96 patientclinician communication relative risk 162 95 ci 142 184 2 0 ptdas reduced decisional conflict mean difference 959 95 ci 1894 024 2 84 proportion undecided relative risk 039 95 ci 028 053 2 75 ptdas affect anxiety standardized mean difference 002 95 ci 022 026 2 70 1 trial looked clinical outcomes hemoglobin a1c five 12 ptda studies compared outcomes disadvantaged standing found outcomes improved socially disadvantaged participants evidence indicated intervention characteristics effective results similar sdm intervention trials limitations sixteen ptda studies overall unclear risk bias heterogeneity high outcomes studies shortterm followup conclusions ptdas led better outcomes among socially disadvantaged populations reduce health inequalities could determine intervention features effective box see text
https://doi.org/10.1371/journal.pone.0251963
Aikaterini Kassavou|Venus Mirzaei|James Brimicombe|Simon Edwards|Efthalia Massou|A. Toby Prevost|Simon J. Griffin|Stephen Sutton
A Highly Tailored Text and Voice Messaging Intervention to Improve Medication Adherence in Patients With Either or Both Hypertension and Type 2 Diabetes in a UK Primary Care Setting: Feasibility Randomized Controlled Trial of Clinical Effectiveness
2,020
University of Cambridge|University of Cambridge|University of Cambridge|University of Cambridge|University of Cambridge|Imperial College London|University of Cambridge|University of Cambridge
background efficacy highly tailored digital intervention support medication adherence feasibility support clinical effectiveness adjunct primary care setting evaluated objective trial aimed assess behavioral efficacy highly tailored digital intervention support medication adherence evaluate feasibility clinical effectiveness patients either hypertension type 2 diabetes also examined quality life mechanisms behavior change intervention fidelity engagement satisfaction also explored methods multicenter individually randomized controlled trial 2 parallel groups intervention group received highly tailored text message interactive voice response intervention 12 weeks control group received usual care medication adherence measured using selfreports assessorblinded practice records repeat prescription systolic blood pressure glucose levels assessed nurses blinded group allocation practice visits 3 months followup questionnaires obtained data assess intervention mechanisms action satisfaction digital log files captured data evaluate fidelity engagement results total 135 nonadherent patients 62135 46 female 122135 903 aged 50 years randomly allocated intervention n79 control group n56 13 18135 lost followup medication adherence significantly improved intervention group compared control group t116227 p02 2tailed systolic blood pressure 06 mmhg 95 ci 7423 6301 hemoglobin a1c 45 mmolmol 95 ci 13099 4710 lower intervention group compared control group changes intentional nonadherence nonintentional nonadherence explained improvements medication adherence intervention group beta074 se0464 p04 control group beta00 se 135 p37 intervention 100 fidelity median 12 days engagement 76 overall satisfaction conclusions trial first conducted united kingdom showed among nonadherent patients either hypertension type 2 diabetes highly tailored digital intervention effective improving treatment adherence feasible obtain clinically meaningful outcomes changes intentional nonintentional nonadherence predicted improvements medication adherence intervention high fidelity engagement satisfaction future research using rigorous design needed evaluate clinical effectiveness costeffectiveness intervention primary care trial registration international standard randomized controlled trial number isrctn 10668149 httpwwwcontrolledtrialscomisrctn10668149
https://doi.org/10.1192/bjp.bp.107.047704
James Tosin Akinlua|R Meakin|Aminu Umar|Nick Freemantle
Current Prevalence Pattern of Hypertension in Nigeria: A Systematic Review
2,015
Roland Hill (United Kingdom)|The Royal Free Hospital|University College London|Roland Hill (United Kingdom)|The Royal Free Hospital|University College London|University of Salford|Roland Hill (United Kingdom)|The Royal Free Hospital|University College London
background global burden hypertension noncommunicable diseases ncds rapidly increasing african continent seems affected region world prevalence hypertension nigeria forms substantial portion total burden africa large population country currently estimated 170 million objective purpose systematic review summarise date data prevalence distribution hypertension nigeria prevalence studies methods search following databases pubmed embase cardiovascular infobase 1968 till date conducted identify studies provide estimates prevalence hypertension nigeria results search yielded total 1748 hits 45 relevant studies met inclusion criteria review overall crude prevalence hypertension ranged 01 95ci01 03 175 95 ci 136 214 children 21 95ci 14 28 472 95ci 436 508 adults depending benchmark used diagnosis hypertension setting study conducted sex ethnic group crude prevalence hypertension ranged 62 95ci 40 84 489 95ci 423 555 men 10 95ci 81 12 473 95ci 43 516 women studies prevalence hypertension higher males females addition prevalence across urban rural ranged 95 95ci 136 214 516 95ci 498 534 48 95ci 29 67 43 95ci 421 439 respectively conclusions prevalence hypertension high among nigerian population appropriate interventions need developed implemented reduce preventable burden hypertension especially primary health care centres first point call 55 nigerian population
https://doi.org/10.1371/journal.pone.0045168
null
null
2,017
University of Ghana|University of Ghana|University of Amsterdam
background government ghana introduced national health insurance scheme nhis 2004 goal achieving universal coverage within 5 years evidence however shows expanding nhis coverage especially retaining members remained challenge multilevel perspective employed conceptual framework methodological tool examine enrolment retention nhis remains low methods household survey conducted 20 months educational promotional activities aimed improving enrolment retention rates 15 communities central eastern regions ers ghana observation indepth interviews informal conversations used collect qualitative data forty key informants community members health providers district health insurance schemes dhiss staff purposely selected two casestudy communities central region cr interviewed several community members health providers dhiss staff also engaged informal conversations five communities region also four staff ministry health moh ghana health service ghs national health insurance authority nhia engaged indepth interviews descriptive statistics used analyse quantitative data qualitative data analysed using thematic content analysis results results show factors influence enrolment retention nhis multidimensional cut across stakeholders people enrolled renewed membership nhis benefits health providers positive behaviour barriers enrolment retention included poverty traditional risksharing arrangements influence people enrol renew membership need healthcare dissatisfaction health providers behaviour service delivery challenges conclusion given multidimensional nature barriers enrolment retention suggest nhia engage dhiss health providers stakeholders develop implement intervention activities eliminate corruption shortage drugs health facilities enforce compulsory enrolment stated nhis policy move scheme towards universal coverage
https://doi.org/10.1371/journal.pone.0194337
Gabriel Chamie|Dalsone Kwarisiima|Tamara D. Clark|Jane Kabami|Vivek Jain|Elvin Geng|Maya Petersen|Harsha Thirumurthy|Moses R. Kamya|Diane V. Havlir|Edwin D. Charlebois
Leveraging Rapid Community-Based HIV Testing Campaigns for Non-Communicable Diseases in Rural Uganda
2,012
MUJHU Research Collaboration|University of California, San Francisco|MUJHU Research Collaboration|University of California, San Francisco|MUJHU Research Collaboration|University of California, San Francisco|MUJHU Research Collaboration|University of California, San Francisco|MUJHU Research Collaboration|University of California, San Francisco|University of California, Berkeley|University of North Carolina at Chapel Hill|Makerere University|MUJHU Research Collaboration|University of California, San Francisco|MUJHU Research Collaboration|University of California, San Francisco
background high burden undiagnosed hiv subsaharan africa limits treatment prevention efforts communitybased hiv testing campaigns address challenge provide untapped opportunity identify noncommunicable diseases ncds tested feasibility diagnostic yield integrating ncd communicable diseases rapid hiv testing referral campaign residents rural ugandan parish methods fiveday multidisease campaign offering diagnostic preventive treatment referral services performed may 2011 services included pointofcare screening hiv malaria tb hypertension diabetes fingerprick diagnostics eliminated need phlebotomy hivinfected adults met clinic staff peer counselors onsite cd4100l underwent intensive counseling rapid referral antiretroviral therapy art community participation casefinding yield linkage care three months postcampaign analyzed results 6300 residents 23233150 74 adults 20203150 69 children participated estimated 95 52 adult female male residents participated respectively adult hiv prevalence 78 46 hivinfected adults newly diagnosed thirtynine percent new hiv diagnoses linked care pilot subgroup cd4100 83 linked started art within 10 days malaria identified 10 children hypertension diabetes 28 35 adults screened respectively sixtyfive percent hypertensives 23 diabetics new diagnoses 43 61 linked care respectively screening identified suspected tb 87 hivinfected 19 hivuninfected adults 52 percent hivuninfected tb suspects linked care conclusions integrated campaign engaging 74 adult residents identified high burden undiagnosed hiv hypertension diabetes improving male attendance optimizing linkage care require new approaches campaign demonstrates feasibility integrating hypertension diabetes communicable diseases hiv initiatives
https://doi.org/10.2196/31752
Madison Milne?Ives|Caroline de Cock|Ernest Lim|Melissa Harper Shehadeh|Nick de Pennington|Guy Mole|Eduardo Normando|Edward Meinert
The Effectiveness of Artificial Intelligence Conversational Agents in Health Care: Systematic Review
2,020
Oxford Research Group|University of Oxford|Oxford Research Group|University of Oxford|Imperial College Healthcare NHS Trust|University of Geneva|Oxford University Hospitals NHS Trust|Oxford University Hospitals NHS Trust|Imperial College Healthcare NHS Trust|University of Plymouth|Oxford Research Group|University of Oxford|Imperial College London
background high demand health care services growing capability artificial intelligence led development conversational agents designed support variety healthrelated activities including behavior change treatment support health monitoring training triage screening support automation tasks could free clinicians focus complex work increase accessibility health care services public overarching assessment acceptability usability effectiveness agents health care needed collate evidence future development target areas improvement potential sustainable adoption objective systematic review aims assess effectiveness usability conversational agents health care identify elements users like dislike inform future research development agents methods pubmed medline ovid embase excerpta medica database cinahl cumulative index nursing allied health literature web science association computing machinery digital library systematically searched articles published since 2008 evaluated unconstrained natural language processing conversational agents used health care endnote version x9 clarivate analytics reference management software used initial screening fulltext screening conducted 1 reviewer data extracted risk bias assessed one reviewer validated another results total 31 studies selected included variety conversational agents including 14 chatbots 2 voice chatbots 6 embodied conversational agents 3 interactive voice response calls virtual patients speech recognition screening systems 1 contextual questionanswering agent 1 voice recognition triage system overall evidence reported mostly positive mixed usability satisfaction performed well 2730 2631 positive mixed effectiveness found threequarters studies 2330 however several limitations agents highlighted specific qualitative feedback conclusions studies generally reported positive mixed evidence effectiveness usability satisfactoriness conversational agents investigated qualitative user perceptions mixed quality many studies limited improved study design reporting necessary accurately evaluate usefulness agents health care identify key areas improvement research also analyze costeffectiveness privacy security agents international registered report identifier irrid rr210219616934
https://doi.org/10.1136/bmjgh-2019-001535
Baligh R. Yehia|Alisa J. Stephens?Shields|John A. Fleishman|Stephen A. Berry|Allison L. Agwu|Joshua P. Metlay|Richard D. Moore|W. Christopher Mathews|Ank E. Nijhawan|Richard M. Rutstein|Aditya H. Gaur|Kelly A. Gebo
The HIV Care Continuum: Changes over Time in Retention in Care and Viral Suppression
2,015
University of Pennsylvania|Agency for Healthcare Research and Quality|Johns Hopkins Medicine|Johns Hopkins University|Johns Hopkins Medicine|Johns Hopkins University|Massachusetts General Hospital|Johns Hopkins Medicine|Johns Hopkins University|University of California, San Diego|The University of Texas Southwestern Medical Center|Children's Hospital of Philadelphia|St. Jude Children's Research Hospital|Johns Hopkins Medicine|Johns Hopkins University
background hiv care continuum diagnosis linkage care retention care receipt antiretroviral therapy art viral suppression used identify opportunities improving delivery hiv care continuum steps typically calculated conditional manner number persons completing prior step serving base population next step approach may underestimate prevalence viral suppression excluding patients suppressed meet standard definitions retention care understanding retention care viral suppression interact change time may improve ability intervene steps continuum methods followed 17140 patients 11 us hiv clinics 20102012 calendar year patients classified one five categories 1 retainedsuppressed 2 retainednotsuppressed 3 notretainedsuppressed 4 notretainednotsuppressed 5 lost followup calendar years 2011 2012 retained individuals completing 2 hiv medical visits separated 90 days year persons retained completed 1 hiv medical visit year meet retention definition persons lost followup hiv medical visits year hiv viral suppression defined hiv1 rna 200 copiesml last measure year multinomial logistic regression used determine probability patients transitioning retentionsuppression categories 2010 2011 2010 2012 adjusting age sex raceethnicity hiv risk factor insurance status cd4 count use art results overall 658 patients retainedsuppressed 174 retainednotsuppressed 100 notretainedsuppressed 68 notretainednotsuppressed 2010 595 patients maintained status 2011 kappa0458 533 maintained status 2012 kappa0437 conclusions counting patients notretainedsuppressed virally suppressed commonly done hiv care continuum underestimated proportion suppressed 13 applying care continuum longitudinal manner enhance utility
https://doi.org/10.2196/20073
Timothy Pearman|Jennifer L. Beaumont|Daniel K. Mroczek|M. O'Connor|David Cella
Validity and usefulness of a single?item measure of patient?reported bother from side effects of cancer therapy
2,017
Northwestern University|Northwestern University|Northwestern University|Northwestern University|Northwestern University
background improving efficacy cancer treatment resulted increasing array treatmentrelated symptoms associated burdens imposed individuals undergoing aggressive treatment disease often clinical trials compare therapies different types severities adverse effects whether rated clinicians patients difficult know side effect profile disruptive bothersome patients simple summary index bother help adjudicate variability adverse effects across treatments compared methods across 4 studies total 5765 patients enrolled cooperative group studies industrysponsored clinical trials subjects current study patients diagnosed range primary cancer sites including bladder brain breast colonrectum headneck hepatobiliary kidney lung ovary pancreas prostate well leukemia lymphoma patients administered functional assessment cancer therapygeneral version factg single item bothered side effects treatment gp5 rated 5point likert scale part factg determine validity useful summary measure patient perspective correlated individual aggregated clinicianrated adverse events patient reports general ability enjoy life results analyses pharmaceutical trials demonstrated mean gp5 scores bothered side effects treatment significantly differed maximum adverse event grade p lt001 trials clear trend toward increasing gp5 scores level increasing adverse event grade effect sizes ranged 013 046 analyses cooperative group trials demonstrated significant correlation gp5 item gf3 able enjoy life predicted direction conclusions single factg item bothered side effects treatment significantly associated clinicianreported adverse events patients ability enjoy lives promise overall summary measure burden given set treatment toxicities compared another future research identify contribution individual side effects compared one another terms may contribute overall bother cancer 20181249917 2017 american cancer society
https://doi.org/10.1017/gmh.2018.2
Jean?Phillip Okhovat|Derek Beaulieu|Hensin Tsao|Allan C. Halpern|Dominique S. Michaud|Shimon Shaykevich|Alan C. Geller
The first 30 years of the American Academy of Dermatology skin cancer screening program: 1985-2014
2,018
Stanford Health Care|Beth Israel Deaconess Medical Center|Harvard University|Tufts University|Massachusetts General Hospital|Harvard University|Memorial Sloan Kettering Cancer Center|Brigham and Women's Hospital|Harvard University|Harvard University
background incidence melanoma rising faster preventable cancer united states american academy dermatology sponsored free skin cancer education screenings conducted volunteer dermatologists united states since 1985 objective aimed assess american academy dermatologys national skin cancer screening program 1986 2014 analyzing risk factor profile access dermatologic services examination results methods conducted several detailed statistical analyses screening population results 1986 2014 records available 2046531 screenings 1963141 96 subjected detailed analysis men comprised 38 participants number annual screenings reached approximately 100000 1990 remained relatively stable thereafter 1991 2014 data 1995 1996 2000 unavailable clinical diagnoses rendered 20628 melanomas 156087 dysplastic nevi 32893 squamous cell carcinomas 129848 basal cell carcinomas 21 screenees regular dermatologist clinical diagnosis skin cancer likely general screening population uninsured limitations inability verify clinical diagnoses histopathologically conclusion findings suggest spotme program detected thousands skin cancers may gone undetected experienced delay detection incidence melanoma rising faster preventable cancer united states american academy dermatology sponsored free skin cancer education screenings conducted volunteer dermatologists united states since 1985 aimed assess american academy dermatologys national skin cancer screening program 1986 2014 analyzing risk factor profile access dermatologic services examination results conducted several detailed statistical analyses screening population 1986 2014 records available 2046531 screenings 1963141 96 subjected detailed analysis men comprised 38 participants number annual screenings reached approximately 100000 1990 remained relatively stable thereafter 1991 2014 data 1995 1996 2000 unavailable clinical diagnoses rendered 20628 melanomas 156087 dysplastic nevi 32893 squamous cell carcinomas 129848 basal cell carcinomas 21 screenees regular dermatologist clinical diagnosis skin cancer likely general screening population uninsured inability verify clinical diagnoses histopathologically findings suggest spotme program detected thousands skin cancers may gone undetected experienced delay detection
https://doi.org/10.1371/journal.pntd.0005155
Peggy Liu|Ling?Ling Yeh|Jiun?Yi Wang|Shao-Ti Lee
Relationship Between Levels of Digital Health Literacy Based on the Taiwan Digital Health Literacy Assessment and Accurate Assessment of Online Health Information: Cross-Sectional Questionnaire Study
2,020
Asia University|Dharma Drum Institute of Liberal Arts|Asia University|China Medical University Hospital|China Medical University
background increasing amount health information available internet makes important ever ensure people judge accuracy information prevent harm may possible platforms set protective mechanisms depending level digital health literacy thereby decrease possibility harm misuse health information objective study aimed create instrument digital health literacy assessment dhla based ehealth literacy scale eheals categorize participants level risk misinterpreting health information high medium lowrisk groups methods study developed dhla constructed online health information bank correct incorrect answers receiver operating characteristic curve analysis used detect cutoff value dhla using 5 items randomly selected online health information bank classify users low medium high risk misjudging health information provided information relationship risk group digital health literacy accurate judgement online health information study participants taiwanese residents aged 20 years older snowball sampling used internet questionnaires anonymously completed participants reliability validity dhla examined logistic regression used analyze factors associated risk groups dhla results study collected 1588 valid questionnaires online health information bank included 310 items health information classified easy 147 items moderate 122 items difficult 41 items based difficulty judging accuracy internal consistency dhla satisfactory 87 factor analysis construct validity found three factors accounting 766 variance receiver operating characteristic curve analysis found 106 people high risk 1368 medium risk 114 low risk misinterpreting health information original grouped cases 896 correctly classified discriminate analysis logistic regression analysis showed participants high risk misjudging health information lower education level lower income poorer health also rarely never browsed internet differences statistically significant conclusions dhla score could distinguish low medium high risk misjudging health information internet health information platforms internet could consider incorporating dhla set mechanism protect users misusing health information avoid harming health
https://doi.org/10.1093/ije/dyq179
Nurten Özen|Bilge Bal Özkaptan|Sabahat Co?kun|Füsun Terzio?lu
Health literacy of nursing students and its effective factors
2,019
Istinye University|Sinop University|Gülhane Askerî T?p Akademisi|Atilim University
background insufficiency health literacy negatively affects national economy leads increased health service expenditure important individuals accurate healthrelated information reduce negative effects aim aim study examine health literacy nursing students effective factors methods descriptive study carried students nursing department vocational school health sciences september october 2018 turkey semistructured questionnaire regarding descriptive features participants european health literacy scale used data collection results study included 283 nursing students 293 problematiclimited health literacy level study found statically significant difference student year high school graduation familys income level total mean score hlseu scale conclusion subject health literacy integrated educational program nursing students nurses important workforce health services awareness subject raised
https://doi.org/10.1371/journal.pone.0056688
Hee Yun Lee|Seok Won Jin|Carrie Henning?Smith|Jong?Wook Lee|Jaegoo Lee
Role of Health Literacy in Health-Related Information-Seeking Behavior Online: Cross-sectional Study
2,021
University of Alabama|University of Memphis|University of Minnesota|Harvard Global Health Institute|Harvard University|Jackson State University
background internet emerged main venue health information delivery healthrelated activities however studies examined health literacy determines online healthrelated behavior objective aim study investigate current level healthrelated informationseeking using internet health literacy access technology sociodemographic characteristics impact healthrelated informationseeking behavior methods conducted crosssectional study survey minnesotan adults n614 examine health literacy access technology healthrelated informationseeking internet use used multivariate regression analysis assess relationship healthrelated informationseeking internet health literacy access technology controlling sociodemographic characteristics results better health literacy 35 se 012 greater access technological devices eg mobile phone computer tablet pc 06 se 019 associated healthrelated informationseeking behavior internet adjusting sociodemographic characteristics possession graduate degree 28 se 007 female gender 15 se 005 poor health 22 se 006 participation social groups 13 se 005 annual health exam 35 se 012 associated online healthrelated informationseeking conclusions findings indicate access online healthrelated information uniformly distributed throughout population may exacerbate disparities health health care research policy practice attention needed address disparities access health information well ensure quality information improve health literacy
https://doi.org/10.1371/journal.pone.0026132
Toshiharu Mitsuhashi
Effects of two-week e-learning on eHealth literacy: a randomized controlled trial of Japanese Internet users
2,018
Okayama University Hospital
background internet widely used source information people searching medical healthcare information however information found internet several drawbacks ability consume accurate health information internet ehealth literacy increasingly important studys goal clarify extent ehealth literacy improved elearning randomized controlled trial methods data collected 301 japanese adults online survey participants assigned intervention elearning ehealth literacy group control group 11 ratio intervention group included 148 participants 153 participants control group participants provided information baseline demographic characteristics selfrated health frequency internet searching ehealth literacy scale eheals main measure ehealth literacy data secondary outcomes healthy eating literacy scale skill evaluating retrieved search results obtained baseline followup score difference calculated subtracting score baseline score followup linear regression analysis multinomial regression analysis performed using differences score dependent variables intervention explanatory variable intentiontotreat analysis employed results results participants responded questions times analyzed 134 intervention group 148 control group eheals increased 157 points due intervention effect score change 157 95 ci 009305 p 0037 skills evaluating retrieved search results improved intervention group control group relative risk ratio 247 95 confidence interval 133 459 p 0004 large differences baseline intervention control groups eheals healthy eating literacy scale skill evaluating retrieved search results however followup intervention group improved control group eheals skill evaluating retrieved search results discussion ehealth literacy improved elearning evidenced change eheals scores increased skill evaluating retrieved search results significant effect elearning include content healthy eating healthy eating literacy scale scores indicates scores increase much due effects elearning sometimes seen hawthorne effect although statistically significant effect size small therefore future research necessary verify clinical implications sum study suggests elearning effective way improve ehealth literacy
https://doi.org/10.1177/107327480701400409
Shu Ching Yang|Wan-Chen Hsu|Chia-Hsun Chiang
The Associations Among Individual Factors, Media Literacy, and Dietary Supplement Use Among College Students: Cross-Sectional Study
2,020
National Sun Yat-sen University|National University of Kaohsiung|National Sun Yat-sen University
background mass media condemned encouraging young people take dietary supplements ds media literacy includes authors audiences aa messages meanings mm representation reality rr domains new approach teaching young adults make better informed health decisions however clear domains important media literacy education objective purpose study investigate associations among individual factors media literacy ds use methods survey instrument included demographic items ds media literacy scale dsmls ds use items users nonusers types ds current use ds intention use ds future dsmls 11item instrument designed assess college students aa mm rr media literacy relation ds total 467 taiwanese college students participated study descriptive statistical analysis logistic regression analysis multiple regression analysis conducted results total 338467 724 participants reported using ds 176467 377 consumed 3 supplements moreover mm media literacy domain associated ds user odds ratio 063 p002 current ds use 10 p02 intention use ds future 12 p011 finally perceived importance health positively related current ds use 18 p001 intention use ds future 18 p001 conclusions study showed majority taiwanese college students ds users used multiple types supplements moreover students lower mm media literacy likely ds users take ds frequently higher intentions future frequent ds use finally placed extreme importance health likely take ds frequently higher intentions future frequent ds use
https://doi.org/10.1192/bjp.2018.263
Martin H. Voss|Albert Reising|Cheng Yuan|Parul Patel|Mahtab Marker|Fengshen Kuo|Timothy A. Chan|Toni K. Choueiri|James J. Hsieh|A. Ari Hakimi|Robert J. Motzer
Genomically annotated risk model for advanced renal-cell carcinoma: a retrospective cohort study
2,018
Memorial Sloan Kettering Cancer Center|Novartis (United States)|Novartis (United States)|Novartis (United States)|Novartis (United States)|Memorial Sloan Kettering Cancer Center|Memorial Sloan Kettering Cancer Center|Dana-Farber Brigham Cancer Center|Brigham and Women's Hospital|Dana-Farber Cancer Institute|Washington University in St. Louis|Memorial Sloan Kettering Cancer Center|Memorial Sloan Kettering Cancer Center
background memorial sloan kettering cancer center mskcc risk model established prognostic tool metastatic renalcell carcinoma integrates clinical laboratory data agnostic tumour genomics several mutations including bap1 pbrm1 prognostic value renalcell carcinoma using two independent clinical trial datasets patients metastatic renalcell carcinoma aimed study whether addition mutation status several candidate prognostic genes mskcc model could improve models prognostic performance methods retrospective cohort study used available formalinfixed paraffinembedded tumour tissue clinical outcome data patients metastatic renalcell carcinoma assigned treatment tyrosine kinase inhibitors comparz trial training cohort n357 record3 trial validation cohort n258 eligible patients trials treatmentnaive histologically confirmed advanced metastatic renalcell carcinoma karnofsky performance status score least 70 cohort data patients treatment groups sunitinib pazopanib training cohort everolimus sunitinib validation cohort pooled analysis training cohort tumour tissue used evaluate somatic mutations nextgeneration sequencing association cancerspecific outcomes overall survival progressionfree survival overall response mutation status six genes interest bap1 pbrm1 tp53 tert kdm5c setd2 tested genes prognostic value setting added mskcc risk model create genomically annotated version validation cohort used independently test prognostic value annotated model compared original mskcc risk model findings 357 32 1110 patients assigned protocol treatment comparz study august 2008 september 2011 evaluable mutation status clinical outcomes training cohort independent validation cohort included 258 55 471 evaluable patients enrolled october 2009 june 2011 record3 study training cohort presence mutation bap1 tp53 absence mutation pbrm1 prognostic terms overall survival tp53wtbap1mut tp53mutbap1wt tp53mutbap1mut vs tp53wtbap1wt hazard ratio hr 157 95 ci 121204 p00008 pbrm1wt vs pbrmmut hr 158 116214 p00035 mutation status three prognostic genes added original mskcc risk model create genomically annotated version distribution participants training cohort three risk groups original mskcc model changed 87 24 357 patients deemed favourable risk 217 61 intermediate risk 53 15 poor risk distribution across four risk groups genomically annotated risk model 36 10 357 deemed favourable risk 77 22 good risk 108 30 intermediate risk 136 38 poor risk addition genomic information improved model performance predicting overall survival cindex original model 0595 95 ci 05570634 vs new model 0637 05950679 progressionfree survival 0567 95 ci 05290604 vs 0602 05600643 adequate discrimination proportion patients achieved objective response cochranarmitage onesided p00014 analyses validation cohort confirmed superiority genomically annotated risk model original version interpretation mutation status bap1 pbrm1 tp53 independent prognostic value patients advanced metastatic renalcell carcinoma treated firstline tyrosine kinase inhibitors improved stratification patients across risk groups use genomically annotated model including mutational status three genes warrants investigation prospective trials could use model stratify patients metastatic renalcell carcinoma clinical trials funding novartis pharmaceuticals corporation mskcc support grantcore grant j randall kathleen l macdonald research fund
https://doi.org/10.1002/(sici)1097-0142(20000515)88:10<2398::aid-cncr26>3.0.co;2-i
Margaret E Kruk|Sandro Galea|Marta R. Prescott|Lynn P. Freedman
Health care financing and utilization of maternal health services in developing countries
2,007
Columbia University|University of Michigan–Ann Arbor|University of Michigan–Ann Arbor|Columbia University|University of Michigan–Ann Arbor|Columbia University
background millennium development goals call 75 reduction maternal mortality 1990 2015 skilled birth attendance emergency obstetric care including caesarean section two important interventions reduce maternal mortality although international pressure rising increase donor assistance essential health services developing countries know less whether government private sector effective financing essential services developing countries
https://doi.org/10.1002/14651858.cd005233.pub3
Agnes Fátima Pereira Cruvinel|Daniela Alejandra Cusicanqui Méndez|Juliana Gomes Ramalho de Oliveira|E. Gutierres|Matheus Lotto|Maria Aparecida Andrade Moreira Machado|Thaís Marchini de Oliveira|Thiago Cruvinel
The Brazilian version of the 20-item rapid estimate of adult literacy in medicine and dentistry
2,017
Universidade Federal da Fronteira Sul|Universidade de São Paulo|Universidade de São Paulo|Universidade de São Paulo|Universidade de São Paulo|Universidade de São Paulo|Universidade de São Paulo|Universidade de São Paulo
background misunderstanding specific vocabulary may hamper patienthealth provider communication 20item rapid estimate adult literacy medicine dentistry realmd20 constructed screen patients ability reading medicaldental terminologies simple rapid way study aimed perform crosscultural adaptation validation instrument application brazilian dental patients methods crosscultural adaptation performed conceptual equivalence verbatim translation semantic item operational equivalence backtranslation 200 participants responded adapted version realmd20 brazilian version rapid estimate adult literacy dentistry breald30 ten questions brazilian national functional literacy index bnfli questionnaire sociodemographic oral healthrelated questions statistical analysis conducted assess reliability validity realmd20 p lt 005 results sample composed predominantly women 555 whitebrown 76 individuals average age 3902 years old 1528 average realmd20 score 1748 259 range 820 displayed good internal consistency cronbachs alpha 0789 testretest reliability icc 073 95 ci 066 079 exploratory factor analysis six factors extracted according kaisers criterion factor eigenvalue 453 comprised four terms jaundice amalgam periodontitis abscess accounted 2518 total variance factor ii eigenvalue 188 comprised four terms gingivitis instruction osteoporosis constipation accounted 1046 total variance first four factors accounted 521 total variance realmd20 positively correlated breald30 rs 073 p lt 0001 bnfli rs 060 p lt 0001 scores significantly higher among health professionals educated people individuals reported goodexcellent oral health conditions sought preventive dental services distinctly realmd20 scores similar participants visited dentist lt1 year ago 1 year also realmd20 significant predictor selfreported oral health status multivariate logistic regression model considering sociodemographic oral healthrelated confounding variables conclusion brazilian version realmd20 demonstrated adequate psychometric properties screening dental patients relation recognition health specific terms instrument contribute identify individuals important dentalmedical vocabulary limitations order improve health education outcomes personcentered care model
https://doi.org/10.1002/14651858.cd008970.pub3
Tatsuo Akechi|Toru Okuyama|Joji Onishi|Tatsuya Morita|Toshi A Furukawa
Psychotherapy for depression among incurable cancer patients
2,008
Nagoya City University|Nagoya City University|Nagoya University|Seirei Mikatabara General Hospital|Kyoto University
background common psychiatric diagnosis among cancer patients depression diagnosis even common among patients advanced cancer psychotherapy patientpreferred promising strategy treating depression among cancer patients several systematic reviews investigated effectiveness psychological treatment depression among cancer patients however findings conflicting review focused depression among patients incurable cancer objectives investigate effects psychotherapy treating depression among patients advanced cancer conducting systematic review randomized controlled trials rcts search methods searched cochrane pain palliative supportive care group register cochrane controlled trials register medline embase cinahl psycinfo databases september 2005 selection criteria relevant rcts comparing kind psychotherapy conventional treatment adult patients advanced cancer eligible inclusion two independent review authors identified relevant studies data collection analysis two review authors independently extracted data original reports using standardized data extraction forms two independent review authors also assessed methodological quality selected studies according recommendations previous systematic review psychological therapies cancer patients utilized ten internal validity indicators primary outcome standardized mean difference smd change baseline immediate posttreatment scores main results identified total ten rcts total 780 participants data six studies used metaanalyses 292 patients psychotherapy arm 225 patients control arm among six studies four studies used supportive psychotherapy one adopted cognitive behavioural therapy one adopted problemsolving therapy compared treatment usual psychotherapy associated significant decrease depression score smd 044 95 confidence interval ci 008 080 none studies focused patients clinically diagnosed depression authors conclusions evidence rcts moderate quality suggest psychotherapy useful treating depressive states advanced cancer patients however evidence supports effectiveness psychotherapy patients clinically diagnosed depression
https://doi.org/10.1371/journal.pone.0037515
Bharath Chakravarthy|Shashank Somasundaram|Jennifer Mogi|Roshan Burns|Wirachin Hoonpongsimanont|Warren Wiechmann|Shahram Lotfipour
Randomized Pilot Trial Measuring Knowledge Acquisition of Opioid Education in Emergency Department Patients using a Novel Media Platform
2,018
University of California, Irvine|University of California, Irvine|University of California, Irvine|University of California, Irvine|University of California, Irvine|University of California, Irvine|University of California, Irvine
background number active opioid analgesic prescriptions risen steadily causing increases nonmedical opioid use addiction overdose insufficient focus patient discharge instructions contributed lack patient awareness regarding dangers opioids study examines whether educational khan academystyle animation discharge instruction dangers safe usage opioid analgesics elicits higher knowledge acquisition current standard care additionally measures feasibility implementing video discharge instruction emergency department ed methods fiftytwo englishspeaking patients aged 18 years older receiving opioid prescription enrolled study patients randomized 2 groups standard care group received verbal instruction informational sheet whereas video animation group received 6minute video proper usage opioids addition standard care video content sourced samhsagov administered within ed prior discharge groups received 26question test regarding dangers safe usage opioids immediately education unpaired test compared knowledge acquisition 2 groups results fiftyfour patients approached 52 patients enrolled 27 standard group 25 animation group standard care group averaged 65 knowledge acquisition 16826 correct whereas animation group averaged 82 acquisition 21226 correct video animation significantly increased patient knowledge acquisition opioid medications risks proper usage disposal p 001 conclusion concluded medical knowledge acquisition improved video animation group compared current standard care p 001 also concluded feasible implement novel media platform educate patients receiving opioid analgesics ed 961
https://doi.org/10.1371/journal.pone.0064031
Sigita Burokien?|Juozas Raistenskis|Emilija Burokait?|Rimant? ?erkauskien?|Vytautas Usonis
Factors Determining Parents’ Decisions to Bring Their Children to the Pediatric Emergency Department for a Minor Illness
2,017
Vilnius University|Vilnius University|Vilnius University|Vilnius University|Vilnius University
background number children visiting emergency departments eds increasing lithuania therefore aim study determine factors influencing parental decision bring child ed minor illness could managed primary healthcare setting compare parents medical professionals attitudes toward childs health status need urgent care material methods prospective observational study performed tertiarylevel teaching childrens hospital vilnius total 381 patients parents interviewed using original questionnaire based andersens behavioral model healthcare utilization addition medical records patients reviewed identify factors might impact parental decisions bring child ed minor health problem study participants enrolled october 1 2013 august 31 2014 urgency medical care needed provided patients evaluated tertiarylevel triage system results based assessment triage nurses need emergency care patients distributed follows 298 patients 782 needed nonurgent care 83 patients 218 needed urgent care onethird 388 parents reported came ed due childs urgent care need worsened childs health however opinion ed professionals indicated fifth patients required urgent care parents brought children ed without physician referral five times likely visit ed evening hours weekends or5416 95 ci 3259899 p0001 decision come ed without visiting primary care physician made often parents higher income or2153 95 ci 1167397 came due children rash or4303 95 ci 108916995 fever or3463 95 ci 10111876 older parents 207 95 ci 112243506 times likely evaluate childs health unfavorably younger parents conclusions identified predisposing enabling need factors influenced parents decision bring child ed minor health problems could managed primary care physician parents assessed childs condition critically thought child required urgent medical aid frequently healthcare professionals
https://doi.org/10.1371/journal.pone.0156945
Stacy N. Davis|Shannon M. Christy|Enmanuel A. Chavarria|Rania Abdulla|Steven K. Sutton|Alyssa R. Schmidt|Susan T. Vadaparampil|Gwendolyn P. Quinn|Vani N. Simmons|Chukwudi B. Ufondu|Chitra Ravindra|Ida Schultz|Richard G. Roetzheim|David Shibata|Cathy D. Meade|Clement K. Gwede
A randomized controlled trial of a multicomponent, targeted, low?literacy educational intervention compared with a nontargeted intervention to boost colorectal cancer screening with fecal immunochemical testing in community clinics
2,016
Rutgers, The State University of New Jersey|Moffitt Cancer Center|Moffitt Cancer Center|University of South Florida|Moffitt Cancer Center|University of South Florida|Moffitt Cancer Center|Moffitt Cancer Center|University of South Florida|Moffitt Cancer Center|Moffitt Cancer Center|Moffitt Cancer Center|University of South Florida|Moffitt Cancer Center|University of South Florida|Florida Department of Health|Florida Department of Health|Premier Community Health|Moffitt Cancer Center|University of South Florida|Moffitt Cancer Center|University of South Florida|University of Tennessee Health Science Center|Moffitt Cancer Center|University of South Florida|Moffitt Cancer Center|University of South Florida
background objective current study improve colorectal cancer crc screening uptake fecal immunochemical test fit current study investigated differential impact multicomponent targeted lowliteracy educational intervention compared standard nontargeted educational intervention methods patients aged 50 75 years average crc risk uptodate crc screening recruited either federally qualified health center primary care community health clinic patients randomized intervention condition targeted photonovella bookletdvd plus fit kit comparison condition standard centers disease control prevention brochure plus fit kit main outcome screening fit within 180 days delivery intervention results 416 participants 54 female participants racially ethnically diverse 66 white 10 hispanic 28 african american predominantly low income insured majority county health insurance overall fit completion rate 81 781 participants intervention versus 835 comparison condition completing fit p 17 multivariate analysis health insurance found primary factor predicting lack fit screening adjusted odds ratio 210 95 confidence interval 104426 p 04 conclusions multicomponent targeted lowliteracy materials found significantly different effective increasing fit uptake compared nontargeted materials provision fit test plus education may provide key impetus improve completion crc screening type educational material targeted vs nontargeted may matter less findings current study provide unique opportunity clinics adopt fit choose type patient education materials based clinic provider patient preferences cancer 201712313901400 2016 american cancer society
https://doi.org/10.1002/cncr.28483
Melissa M. Garrido|Shannon Harrington|Holly G. Prigerson
End?of?life treatment preferences: A key to reducing ethnic/racial disparities in advance care planning?
2,014
James J. Peters VA Medical Center|Geriatric Research Education and Clinical Center|Icahn School of Medicine at Mount Sinai|Dana-Farber Cancer Institute|University of Massachusetts Boston|Cornell University
background objective study identify targets interventions reduce endoflife care disparities among patients advanced cancer authors evaluated degree endoflife care values preferences associated advance care planning within racialethnic minority groups methods coping cancer study recruited patients advanced cancer outpatient clinics 5 states 2002 2008 rates 1 type advance care planningdonotresuscitate dnr ordersreported baseline interviews 606 patients investigated bivariate tests determined associations among dnr order completion religious values treatment preferences within racialethnic groups results nonlatino white patients significantly likely dnr order 45 black 25 latino 20 patients p lt001 preference specific lifeprolonging treatment eg chemotherapy ventilation factor significantly associated higher dnr order likelihood group nonlatino white patients likely latino black patients express preferences lifeprolonging care eg 26 nonlatino white patients 46 black patients 41 latino patients wanted feeding tube would extend life 1 day p lt001 conclusions preferences lifeprolonging care differ dramatically raceethnicity uniform significant association dnr order completion rates across racialethnic groups patients advanced cancer advance care planning interventions target preferences associated dnr orders across racialethnic groups may reach broad patient population reduce endoflife care disparities cancer 201412039813986 2014 american cancer society
https://doi.org/10.1111/jcpp.13303
Edmond L. Paquette|Roger R. Connelly|Isabell A. Sesterhenn|Wei Zhang|Leon Sun|Laurence R. Paquette|Renata Greenspan|David G. McLeod|Judd W. Moul
Improvements in pathologic staging for African-American men undergoing radical retropubic prostatectomy during the prostate specific antigen era
2,001
Armed Forces Institute of Pathology|Armed Forces Institute of Pathology|Uniformed Services University of the Health Sciences|Walter Reed Army Institute of Research|Uniformed Services University of the Health Sciences|Uniformed Services University of the Health Sciences|Walter Reed Army Institute of Research
background objective compare changes pathologic clinical data time africanamerican aa white men prostate carcinoma undergoing radical prostatectomy attempt determine early impact prostate specific antigen psa methods data 195 aa 587 white men underwent radical prostatectomy 1988 1999 equal access tertiary military medical facility collected statistical analysis used determine significance changes rates extracapsular extension ece positive margins pretreatment psa levels age time surgery race time results comparing 198899 results authors found percentage aa men ece decreased 100 348 p 0007 white men 569 432 p 0269 percentage aa men positive margins decreased 100 261 p 00001 white men 412 270 p 0021 mean age surgery decreased 666 599 years aa men p 0001 659 611 years white men p 0001 also psa levels decreased 101 66 ngdl white men p 0001 165 65 ngdl aa men p 0001 conclusions authors believe decrease ece positive margins aa men primarily psa testing coupled improved public awareness equal access care appears reasonable recommend psa testing aa men historically experienced poor outcomes prostate carcinoma cancer 20019226739 2001 american cancer society
https://doi.org/10.1371/journal.pntd.0007075
Corey S. Mackenzie|Kristin Reynolds|John Cairney|David L. Streiner|Jitender Sareen
Disorder-specific mental health service use for mood and anxiety disorders: associations with age, sex, and psychiatric comorbidity
2,011
University of Manitoba|University of Manitoba|McMaster University|McMaster University|University of Toronto|University of Manitoba
background objectives study examine prevalence disorderspecific mental health service use mood anxiety disorders relationships helpseeking age sex psychiatric comorbidity methods authors used wave 2 data national epidemiologic survey alcohol related conditions nesarc included 34653 adults crosstabulations provided helpseeking prevalence rates five anxiety disorders three mood disorders age sex well individuals without comorbid anxiety mood disorders logistic regression analyses explored likelihood helpseeking among younger middleaged adults comparison older adults results prevalence helpseeking highest panic disorder 453 dysthymia 445 lowest specific phobias 78 condition except panic disorder service use likely among middleaged adults especially unlikely among older individuals sex differences treatment seeking favoring women showed modest variability age finally prevalence helpseeking generally lower among individuals without comorbid anxiety mood disorders hillshaped influence age service use attenuated pure group conclusions results study highlight highest prevalence disorderspecific service use among middleaged adults women among individuals panic disorder dysthymia purposes identifying groups need targeted efforts increase service use helpseeking especially unlikely among people suffering specific phobia well among men older adults depression anxiety 019 2011 2011 wiley periodicals inc
https://doi.org/10.1371/journal.pone.0246349
Piangkhuan Phutong|Suparp Thaithae
Social support, health literacy and anxiety among pregnant women during coronavirus 2019 pandemic in Thailand
2,023
Navamindradhiraj University|Navamindradhiraj University
background ongoing coronavirus disease 2019 covid19 pandemic continues significant impact pregnant women particularly vulnerable effects may increase anxiety levels study aims investigate anxiety levels pregnant women covid19 pandemic thailand identify factors predicting anxiety methods researchers collected data online questionnaire november 2021 may 2022 sample included 404 pregnant women questionnaire consisted personal information health literacy related covid19 social support anxiety related covid19 content validity questionnaire verified three experts content validity indices 087 080 087 domain respectively reliability questionnaire 096 health literacy 095 social support 096 anxiety moreover indepth telephone interviews also conducted pregnant women data analyzed using descriptive statistics stepwise multiple regression content analysis results group 404 pregnant women studied results showed pregnant women high level health literacy regarding covid19 pregnancy mean 9636 sd 1423 social support level high level mean 8399 sd 1134 concerned anxiety related covid19 infection pregnancy moderate level mean 4778 sd 1149 factors predicting anxiety pregnant women covid19 outbreak thailand included health literacy related covid19 0468 social support 0283 prediction rate 3280 r 2 0328 statistical significance p amplt 005 conclusion study revealed anxiety level pregnant women covid19 outbreak thailand moderate health literacy covid19 social support predict anxiety level pregnant women
https://doi.org/10.1371/journal.pone.0133043
Isaac Amankwaa|Daniel Boateng|Dan Yedu Quansah|Cynthia Pomaa Akuoko|Catrin Evans
Effectiveness of short message services and voice call interventions for antiretroviral therapy adherence and other outcomes: A systematic review and meta-analysis
2,018
Wellington Hospital|Victoria University of Wellington|University Medical Center Utrecht|Utrecht University|Kwame Nkrumah University of Science and Technology|University of Lausanne|University of Cape Coast|Christian Service University College|Queensland University of Technology|Queen's Medical Centre|University of Nottingham
background potential using mobile phone technologies improve antiretroviral therapy art adherence provided new facet human immunodeficiency virus hiv research quality evidence strength recommendations existing reviews however adequately support largescale adoption intervention review adopted broad selection criteria include mobile phonebased interventions designed improve patients adherence art methods performed systematic review metaanalysis randomized controlled trials quasiexperimental studies pubmed medline embase psychinfo cochrane central register controlled trials central cinahl amed web science searched online abstracts archives relevant conference proceedings trial registries also searched thirtyfive 35 fulltext articles assessed eligibility included studies conducted high low middleincome countries reported art adherence interventions delivered mobile phones standard smartphones form voice calls interactive voice response calls ivr short message service sms results thirteen 13 studies met inclusion criteria 11 used metaanalysis intervention characteristics included studies ranged mobile phone functionalities provision study phones participants sms voice call contents tailored participants specific adherence needs mobile sms interventions improved adherence art compared control conditions 95 ci 159 127198 subgroup analysis scheduled sms significant whereas triggered sms effect adherence art mobile voice calls significantly increase adherence art interventions highly rated 90 participants studies reported experiences satisfaction intervention conclusion scheduled mobile phone textmessaging demonstrated significant improvement adherence art mobile sms adherence interventions allow twoway communication may however acceptable standalone sms reminders seen intrusive producing habituation response fatigue voice calls triggered sms functionalities significant effect adherence art although higher preference voice functionality sms especially limitedresource lowliteracy settings exploration mobile voice functionality possible combination scheduled sms functionality recommended evidence provided study guide implementation mobile phone intervention improve adherence art addressing practical challenges could militate scalability especially resource limited settings
https://doi.org/10.1136/bjophthalmol-2018-313308
Juan Zhang|Xitao Fan|Sum Kwing Cheung|Yaxuan Meng|Zhihui Cai|Biao Hu
The role of early language abilities on math skills among Chinese children
2,017
University of Macau|Hong Kong Baptist University|University of Macau|Central China Normal University|University of Macau
background present study investigated role early language abilities development math skills among chinese k3 students 2000 children china average aged 6 years assessed informal math eg basic number concepts counting objects formal math calculations including addition subtraction skills language abilities nonverbal intelligence methodology correlation analysis showed language abilities strongly associated informal formal math skills regression analyses revealed childrens language abilities could uniquely predict informal formal math skills age gender nonverbal intelligence controlled mediation analyses demonstrated relationship childrens language abilities formal math skills partially mediated informal math skills results current findings indicate 1 childrens language abilities strong predictive values informal formal math skills 2 language abilities impacts formal math skills partially mediation informal math skills
https://doi.org/10.1017/s0033291713001943
Su Lin Lim|Jolyn Johal|Kai Wen Ong|Chad Yixian Han|Yiong Huak Chan|Yin Mei Lee|Wai Mun Loo
Lifestyle Intervention Enabled by Mobile Technology on Weight Loss in Patients With Nonalcoholic Fatty Liver Disease: Randomized Controlled Trial
2,020
National University Health System|National University Hospital|National University Health System|National University Hospital|National University Health System|National University Hospital|National University Health System|National University Hospital|National University of Singapore|National University Health System|National University Hospital|National University Health System|National University Hospital
background prevalence nonalcoholic fatty liver disease nafld reaches 30 asian adult population higher prevalence obese patients weight reduction typically recommended patients high risk diagnosed nafld challenge achieve objective aimed evaluate effect lifestyle intervention mobile app weight loss nafld patients methods prospective randomized controlled trial included 108 adults nafld confirmed steatosis ultrasound body mass index 23 kgm2 recruited fatty liver outpatient clinic patients randomly allocated either control group n53 receiving standard care consisting dietary lifestyle advice trained nurse intervention group n55 utilizing nutritionist buddy nbuddy mobile app addition receiving dietary lifestyle advice dietitian body weight alanine aminotransferase alt aspartate aminotransferase ast waist circumference blood pressure measured baseline 3 6 months intentiontotreat perprotocol analyses used statistical comparisons results intervention group 5fold higher likelihood relative risk 52 p003 95 ci 18154 achieving 5 weight loss compared control group 6 months intervention group also showed greater reductions weight mean 32 sd 41 kg vs mean 05 sd 29 kg plt001 waist circumference mean 29 sd 50 cm vs mean 07 sd 44 cm plt001 systolic blood pressure mean 124 sd 148 mmhg vs mean 24 sd 124 mmhg p003 diastolic blood pressure mean 68 sd 89 mmhg vs mean 09 sd 100 mmhg p001 alt mean 335 sd 404 iul vs mean 115 sd 352 iul p004 ast mean 174 sd 275 ul vs mean 74 sd 176 iul p03 6 months conclusions lifestyle intervention enabled mobile app effective improving anthropometric indices liver enzymes patients nafld treatment modality potential extended larger population scale trial registration australian new zealand clinical trials registry actrn12617001001381 httpstinyurlcomw9xnfmp
https://doi.org/10.1002/cncr.30136
Olivier Galy|Kalina Yacef|Corinne Caillaud
Improving Pacific Adolescents’ Physical Activity Toward International Recommendations: Exploratory Study of a Digital Education App Coupled With Activity Trackers
2,019
University of New Caledonia|University of Sydney|University of Sydney
background prevalence overweight obesity children adolescents dramatically increased pacific island countries territories last decade childhood overweight obesity shortterm consequences also likely lead noncommunicable diseases adulthood major factor contributing rising prevalence insufficient amount daily moderatetovigorous physical activity mvpa pacific region less 50 children adolescents meet international recommendations 11000 steps 60 min mvpa per day although studies shown potential digital technologies change behaviors none proposed guide adolescents toward achieving recommendations objective aims study 1 investigate whether technologybased educational program combines education objective measures physical activity pa selfassessment goal achievement would well received pacific adolescents help change pa behaviors toward international pa recommendations 2 create insightful data analysis methods better understand pa behavior change methods total 24 adolescents aged 12 14 years participated 4week program comprising 8 1hour modules designed develop health literacy physical skills selfpaced usercentered program delivered via app provided healthrelated learning content well goal setting selfassessment tasks pa performed 4week program captured activity tracker support learning help adolescents selfassess achievements personal goals data analyzed using consistency rate daily behavior clustering reveal pa changes particularly regarding adherence international recommendations results consistency rate daily steps revealed adolescents reached 11000 steps per day 48 approximately 34 days per week time first week program peaked 59 approximately 41 days per week toward end program pa data showed overall increase program particularly less active adolescents increased daily steps 15 ultimately reached 11000 steps frequently consistency daily behavior clustering showed 27 increase adherence international recommendations least active adolescents conclusions technologysupported educational programs include selfmonitored pa via activity trackers successfully delivered adolescents schools remote pacific areas new data mining techniques enable innovative analyses pa engagement based international recommendations
https://doi.org/10.1002/cncr.32670
Dorothy Szinay|Andy Jones|Tim Chadborn|Jamie Brown|Felix Naughton
Influences on the Uptake of and Engagement With Health and Well-Being Smartphone Apps: Systematic Review
2,020
University of East Anglia|University of East Anglia|Public Health England|University College London|University of East Anglia
background public health impact health wellbeing digital interventions dependent upon sufficient realworld uptake engagement uptake currently largely dependent popularity indicators eg ranking user ratings app stores may correspond effectiveness rapid disengagement common therefore urgent need identify factors influence uptake engagement health wellbeing apps inform new approaches promote effective use tools objective review aimed understand known influences uptake engagement health wellbeing smartphone apps among adults methods conducted systematic review quantitative qualitative mixed methods studies studies conducted adults included focused health wellbeing smartphone apps reporting uptake engagement behavior studies identified systematic search medical literature analysis retrieval system online medlars online medline embase cumulative index nursing allied health literature cinahl psychinfo scopus cochrane library databases database systems logic programming dblp association computing machinery acm digital library screened proportion screened independently 2 authors data synthesis interpretation undertaken using deductive iterative process external validity checking undertaken independent researcher narrative synthesis findings structured around components capability opportunity motivation behavior change model theoretical domains framework tdf results 7640 identified studies 41 included review factors related uptake u engagement e b identified capability main factors identified app literacy skills b app awareness u available user guidance b health information e statistical information progress e welldesigned reminders e features reduce cognitive load e selfmonitoring features e availability low cost u positive tone personalization e identified physical opportunity factors whereas recommendations health wellbeing apps u embedded health professional support e social networking e possibilities social opportunity factors finally motivation factors included positive feedback e available rewards e goal setting e perceived utility app e conclusions across wide range populations behaviors 26 factors relating capability opportunity motivation appear influence uptake engagement health wellbeing smartphone apps recommendations may help app developers health app portal developers policy makers optimization health wellbeing apps
https://doi.org/10.1002/cncr.31216
Mark D. Griffiths|Daria J. Kuss|Olatz López-Fernández|Halley M. Pontes
Problematic gaming exists and is an example of disordered gaming
2,017
Nottingham Trent University|Nottingham Trent University|Nottingham Trent University|Nottingham Trent University
background recent paper aarseth et al 2016 questioned whether problematic gaming considered new disorder particularly gaming disorder gd identified disorder included next 11th revision world health organizations international classification diseases icd11 methods study uses contemporary literature argue gd included icd11 results aarseth colleagues acknowledge much literature including papers authors individuals experience serious problems video gaming activity seriously problematic yet disordered similar addictions gaming addiction relatively rare essence syndrome ie condition disorder characterized set associated symptoms tend occur specific circumstances consequently everyone exhibit exactly set symptoms consequences partly explains working problematic gaming field often disagree symptomatology conclusions research gaming pathologizing healthy entertainment pathologizing excessive problematic behaviors cause significant psychological distress impairment individuals life two related ultimately distinct phenomena aware gaming pastime activity enjoyed nonproblematically many millions individuals worldwide concluded problematic gaming exists example disordered gaming
https://doi.org/10.1016/j.brs.2013.12.016
Yong B Liu|Yan L Chen|Hui P Xue|Ping Hou
Health Literacy Risk in Older Adults With and Without Mild Cognitive Impairment
2,019
Yangzhou University|Yangzhou University|Yangzhou University|Yangzhou University
background relationship increasing elderly population wideranging neurological conditions led heightened rates cognitive function impairment researchers found health literacy risk may associated cognitive impairment older adults objectives purpose study delineate difference health literacy risk older adults mild cognitive impairment normal cognitive function methods conducted survey study explore health literacy risk older adults without mild cognitive impairment data collected 412 subjects 60 91 years age 260 without 152 mild cognitive impairment june december 2016 china cognitive function measured using minimental status examination montreal cognitive assessment global deterioration scale activities daily living hamilton depression rating scale health literacy measured using chinese citizen health literacy questionnaire results scores total health literacy three dimensions basic health knowledge mind basic skills health lifestyle behavior lower mild cognitive impairment older adults normal cognitive function adequate marginal health literacy levels whereas mild cognitive impairment marginal inadequate health literacy levels using multiple logistic regression analysis found health literacy risk education level age marital status body mass index independent risk factors mild cognitive impairment discussion results suggest low health literacy may predictor mild cognitive impairment screening lower health literacy risk included multidimensional geriatric evaluation
https://doi.org/10.3402/ejpt.v2i0.5881
Nahed O. ElHassan|Shasha Bai|Neal Gibson|Greg J. Holland|James M. Robbins|Jeffrey R. Kaiser
The impact of prematurity and maternal socioeconomic status and education level on achievement-test scores up to 8th grade
2,018
University of Arkansas for Medical Sciences|University of Arkansas for Medical Sciences|University of Central Arkansas|Conway School of Landscape Design|University of Central Arkansas|Conway School of Landscape Design|University of Arkansas for Medical Sciences|Penn State Milton S. Hershey Medical Center
background relative influence prematurity vs maternal social factors socioeconomic status education level academic performance rarely examined objective examine impact prematurity maternal social factors academic performance 3rd 8th grade methods conducted retrospective cohort study infants born 1998 university arkansas medical sciences study sample included 58 extremely low gestational age newborns elgans 2328 weeks 171 preterm 2834 weeks 228 late preterm 3437 weeks 967 term 3742 weeks infants neonatal maternal variables collected including maternal insurance status proxy measure socioeconomic status education level primary outcomes literacy mathematics achievementtest scores 3rd 8th grade linear mixed models used identify significant predictors academic performance twoway interactions grade level gestationalage ga groups social factors tested statistical significance results prematurity social factors gender race gravidity apgar score one minute critical determinants academic performance favorable social factors associated significant increase literacy mathematic scores prematurity associated significant decrease mathematic scores examination ga categories social factors interaction suggested impact social factors test scores similar ga groups furthermore impact social factors varied grade grade literacy influence either ga groups social factors constant across grades mathematics example elgan favorable social factors predicted literacy score 1041 p 001 982 p 001 764 p 01 points higher otherwise similar disadvantaged term infant grades 3 5 8 respectively difference predicted mathematic scores 334 points grades p 05 conclusion significant deficits academic performance elgans compared pt lpt term infants deficit could offset higher ses bettereducated mothers favorable social factors critical childs academic achievement role socioeconomic factors incorporated discussions outcome families preterm infants
https://doi.org/10.1371/journal.pmed.1002800
Shlomo Barak|Samuel S. Wu|Yunfeng Dai|Pamela W. Duncan|Andrea L. Behrman
Adherence to Accelerometry Measurement of Community Ambulation Poststroke
2,014
Kaye Academic College of Education|Sheba Medical Center|Edmond and Lily Safra Children's Hospital|University of Florida|University of Florida|Wake Forest University|University of Louisville|Neurological Surgery
background step activity monitor sam quantifies steps taken home community patient populations although sam used study individuals stroke adherence use sams addressed participants adherence wearing monitor critical obtaining accurate assessments objective purpose study determine rate predictors inferred adherence use sam stroke design crosssectional design used methods communitydwelling individuals n408 2 months stroke moderatetosevere gait impairment gait speed 08 ms studied step activity assessed 2 days sam inferred adherence established 3 periods 600 1200 pm 1201 pm 600 pm 601 pm 1200 adherence defined activity recorded 3 periods percentage participant adherence first day second day days either day calculated demographic clinical characteristics adherers nonadherers compared independent adherence predictors identified means stepwise logistic regression results inferred adherence rates first day second day days either day 68 61 53 76 respectively upper lower extremity impairment balance control endurance significantly different adherers nonadherers hand older age greater balance selfefficacy better walking endurance significant predictors adherence limitations participants individuals subacute stroke therefore findings study may generalized individuals acute chronic phases stroke recovery conclusions strategies improve adherence needed collecting data 1 day samples younger individuals low levels balance selfefficacy walking endurance
https://doi.org/10.1371/journal.pone.0024160
Janeta Nikolovski|Martin H. Koldijk|Gerrit Jan Weverling|John A. Spertus|Mintu P. Turakhia|Leslie A. Saxon|C. Michael Gibson|John Whang|Troy C. Sarich|Robert A. Zambon|Nnamdi Ezeanochie|Jennifer Turgiss|Robyn Jones|Jeff Stoddard|Paul R. Burton|Ann Marie Návar
Factors indicating intention to vaccinate with a COVID-19 vaccine among older U.S. adults
2,021
Johnson & Johnson (United States)|Janssen (United States)|Johnson & Johnson (United States)|Janssen (United States)|Johnson & Johnson (United States)|Janssen (United States)|University of Missouri–Kansas City|Stanford University|University of Southern California|Harvard University|Johnson & Johnson (United States)|Janssen (United States)|Johnson & Johnson (United States)|Janssen (United States)|Johnson & Johnson (United States)|Janssen (United States)|Johnson & Johnson (United States)|Johnson & Johnson (United States)|Johnson & Johnson (United States)|Johnson & Johnson (United States)|Janssen (United States)|Johnson & Johnson (United States)|Janssen (United States)|The University of Texas Southwestern Medical Center|The University of Texas Southwestern Medical Center
background success vaccination efforts curb covid19 pandemic require broad public uptake immunization highlights importance understanding factors associated willingness receive vaccine methods us adults aged 65 older enrolled heartline tm clinical study invited complete covid19 vaccine assessment heartline tm mobile application november 620 2020 factors associated willingness receive covid19 vaccine evaluated using ordered logistic regression well random forest classification algorithm results among 9106 study participants 813 n 7402 responded available demographic data majority 913 reported willingness vaccinated factors strongly associated vaccine willingness beliefs safety efficacy covid19 vaccines vaccines general women black african american respondents reported lower willingness vaccinate among less willing get vaccinated 662 said would talk health provider making decision study positive results first covid19 vaccine outcome study released vaccine willingness increased report conclusions even among older adults highrisk covid19 complications participating longitudinal clinical study 1 11 reported lack willingness receive covid19 vaccine november 2020 variability vaccine willingness gender race education income suggests potential uneven vaccine uptake education health providers directed toward assuaging concerns vaccine safety efficacy help improve vaccine acceptance among less willing trial registration clinicaltrialsgov nct04276441
https://doi.org/10.1093/ije/dyp224
Rory C. O’Connor|Susan Rasmussen|J Miles|Keith Hawton
Self-harm in adolescents: self-report survey in schools in Scotland
2,009
University of Stirling
background suicide rate scotland twice high england however prevalence selfharm unknown aims determine prevalence selfharm adolescents scotland factors associated method total 2008 pupils aged 1516 years completed anonymous lifestyle coping survey information obtained demographic characteristics lifestyle life events problems social influences psychological variables selfharm results selfharm reported 138 respondents majority 71 selfharmed done past 12 months girls approximately 34 times likely report selfharm boys multivariate analyses smoking bullying worries sexual orientation selfharm family anxiety associated selfharm genders addition drug use physical abuse serious boygirlfriend problems selfharm friends low levels optimism also associated selfharm girls conclusions despite markedly different national suicide rates prevalence selfharm scotland similar england girls least three times likely report selfharm boys findings suggest role emotional literacy programmes schools highlight importance promoting positive mental health among adolescents
https://doi.org/10.1177/0272989x11431608
Oon Tek Ng|Angela Chow|Vernon J. Lee|Mark Chen|Mar Kyaw Win|Huei Nuo Tan|Arlene Chua|Yee Sin Leo
Accuracy and User-Acceptability of HIV Self-Testing Using an Oral Fluid-Based HIV Rapid Test
2,012
Tan Tock Seng Hospital|Tan Tock Seng Hospital|National University of Singapore|Tan Tock Seng Hospital|National University of Singapore|Tan Tock Seng Hospital|National University of Singapore|Tan Tock Seng Hospital|National Skin Centre|Tan Tock Seng Hospital|Tan Tock Seng Hospital
background united states fda approved overthecounter hiv selftest facilitate increased hiv testing earlier linkage care assessed accuracy selftesting untrained participants compared healthcare worker hcw testing participants ability interpret sample results useracceptability selftests singapore methodologyprincipal findings crosssectional study involving 200 known hivpositive patients 794 unknown hiv status atrisk participants conducted participants without prior selftest experience performed selftesting guided solely visual instructions followed hcw testing using oraquick advance rapid hiv 12 antibody test results interpreted hcw assess ability interpret results participants provided 3 sample results positive negative invalid interpret 192 participants tested positive hcw testing selftesting positive 186 969 negative 5 26 invalid 1 05 794 participants tested negative hcw testing selftesting negative 791 996 positive 1 01 invalid 2 03 excluding invalid tests selftesting sensitivity 974 95 ci 951 997 specificity 999 95 ci 996 100 interpreting results 96 931 952 correctly read positive negative invalid respectively significant demographic predictors false negative selftesting wrongly interpreting positive invalid sample results negative eightyseven percent would purchase kit overthecounter 89 preferred take hiv tests private 725 749 felt need pre posttest counseling respectively 28 would pay least usd15 test conclusionssignificance selftesting associated high specificity small significant number false negatives incorrectly identifying model results invalid major reason incorrect result interpretation survey responses supportive making selftesting available
https://doi.org/10.1093/ije/dyi190
Julia Dalton|Dianne Rodger|Michael Wilmore|Sal Humphreys|Andrew Skuse|Claire T. Roberts|Vicki L. Clifton
The Health-e Babies App for antenatal education: Feasibility for socially disadvantaged women
2,018
University of Adelaide|University of Adelaide|University of Adelaide|Swinburne University of Technology|University of Adelaide|University of Adelaide|University of Adelaide|University of Adelaide
background use mobile technology phone applications apps proposed efficient means providing health clinical information variety healthcare settings developed healthe babies app android smart phone application pregnant women attending tertiary hospital low socioeconomic community objective providing health information early pregnancy would increase maternal confidence reduce anxiety based earlier research form health communication viewed preferred source information women reproductive age however pilot study poor participation rate 76 n 94 completing study requirements initial findings raised important issues relation difficulties engaging women pregnancy app paper analyses characteristics participants complete study requirements attempt identify potential barriers associated implementation pregnancy app methods retrospective review quantitative qualitative data collected commencement healthe babies app trial related participants communication technology use confidence knowing seek help mental health status maternalfetal attachment parenting confidence engagement use healthe babies app measured completion questionnaire app downloaded data participants phones mental health status confidence selfefficacy measured questionnaires results women similar terms age race marital status level education 94 women 76 complete trial significantly anxious indicated state trait anxiety inventory p 0001 student ttest likely unemployed 50 vs 31 p 0012 student ttest conclusion study provides important information challenges associated implementation pregnancy app socially disadvantaged community data suggests factors including social mental health issues financial constraints technological ability affect womens engagement mobile phone app
https://doi.org/10.1002/cncr.28977
Clemens Scott Kruse|Katharine Heinemann
Facilitators and Barriers to the Adoption of Telemedicine During the First Year of COVID-19: Systematic Review
2,022
Texas State University|Texas State University
background virulent unpredictable nature covid19 combined change reimbursement mechanisms forced enabled rapid adoption telemedicine around world thus important assess effects rapid adoption determine whether barriers adoption today prepandemic conditions objective objective systematic literature review examine research literature published covid19 pandemic identify facilitators barriers associated medical outcomes result adopting telemedicine determine changes occurred industry time methods systematic review performed accordance kruse protocol results reported accordance prisma preferred reporting items systematic reviews metaanalyses guidelines analyzed 46 research articles five continents published first year covid19 pandemic retrieved searches four research databases pubmed medline cinahl science direct web science results reviewers identified 25 facilitator themes observations 12 barrier themes observations 14 results compared control group themes observations overall 22 articles analyzed reported strong satisfaction satisfaction zero reported decline satisfaction 27 reported improvement administrative efficiency results compared control group 14 reported statistically significant difference control group 40 10 reported improvement statistically significant difference medical outcomes using telemedicine modality control group respectively conclusions pandemic encouraged rapid adoption telemedicine also encouraged practices adopt modality regardless challenges identified previous research several barriers remain health policymakers address however health care administrators feel confident modality evidence largely shows safe effective widely accepted
https://doi.org/10.1371/journal.pone.0061335
Saurabh Saluja|Niclas Rudolfson|Benjamin B. Massenburg|John G. Meara|Mark G. Shrime
The impact of physician migration on mortality in low and middle-income countries: an economic modelling study
2,020
Social Change and Development|Yale University|Harvard University|Social Change and Development|Harvard University|World Health Organization - Pakistan|Lund University|Social Change and Development|University of Washington|Plastic Surgery Hospital|Harvard University|Social Change and Development|Boston Children's Museum|Boston Children's Hospital|Harvard University|Social Change and Development|Massachusetts Eye and Ear Infirmary|Harvard University
background estimates global shortage 28 million physicians severe deficiencies especially low middleincome countries lmic unequitable distribution physicians worldwide exacerbated migration physicians lmics highincome countries hic largescale migration numerous economic consequences include increased mortality associated inadequate physician supply lmics methods estimate economic cost lmics due excess mortality associated physician migration use concept value statistical life marginal mortality benefit provided physicians uncertainty estimates evaluated monte carlo analysis results estimate lmics lose us1586 billion 95 ci 34 382 annually due physician migration hics greatest total costs incurred india nigeria pakistan south africa costs considered per cent gross national income cost greatest african region lowincome countries conclusion movement physicians lower higher income settings substantial economic consequences simply result movement human capital also due excess mortality associated loss physicians valuing costs inform international domestic policy discussions meant address issue
https://doi.org/10.1371/journal.pntd.0007085
Alexander Johannes Aloysius Maria van Deursen
Digital Inequality During a Pandemic: Quantitative Study of Differences in COVID-19–Related Internet Uses and Outcomes Among the General Population
2,020
University of Twente
background world health organization considers coronavirus disease covid19 public emergency threatening global health crisis publics need webbased information communication subject focus digital inequality research shown internet access evenly distributed among general population objective aim study provide timely understanding different people use internet meet information communication needs outcomes gain internet use relation covid19 pandemic also sought reveal extent gender age personality health literacy education economic social resources internet attitude material access internet access internet skills remain important factors obtaining internet outcomes people engage corresponding uses methods used webbased survey draw upon sample collected netherlands obtained dataset 1733 respondents older 18 years results men likely engage covid19related communication uses age positively related covid19related information uses negatively related information communication outcomes agreeableness negatively related outcomes information uses neuroticism positively related uses communication outcomes conscientiousness related uses outcomes introversion negatively related communication outcomes finally openness relates positively information uses outcomes physical health negative relationships outcomes health perception contributes positively information uses outcomes traditional literacy positive relationship information uses outcomes education positive relationship information communication uses economic social resources played roles internet attitude positively related information uses outcomes negatively related communication uses outcomes material access internet access contributed uses outcomes finally several indicators outcomes became insignificant accounting engagement internet uses conclusions digital inequality major concern among national international scholars policy makers contribution aimed provide broader understanding case major health pandemic using ongoing covid19 crisis context empirical work several groups people identified vulnerable older people less educated people people physical health problems low literacy levels low levels internet skills generally people already relatively advantaged likely use information communication opportunities provided internet benefit health pandemic less advantaged individuals less likely benefit therefore covid19 crisis also enforcing existing inequalities
https://doi.org/10.2196/16983
Philip Hyland|Ruth Ceannt|F. Daccache|Rawan Daher|Jihan Sleiman|Brynne Gilmore|Sue Byrne|Mark Shevlin|Jamie Murphy|Frédérique Vallières
Are posttraumatic stress disorder (PTSD) and complex-PTSD distinguishable within a treatment-seeking sample of Syrian refugees living in Lebanon?
2,018
Trinity College Dublin|National College of Ireland|Trinity College Dublin|Trinity College Dublin|Trinity College Dublin|University of Ulster|Trinity College Dublin|Trinity College Dublin
background world health organization publish 11 th revision international classification diseases icd11 2018 icd11 include refined model posttraumatic stress disorder ptsd new diagnosis complex ptsd cptsd whereas emerging data supports validity proposals discriminant validity ptsd cptsd yet tested amongst sample refugees methods treatmentseeking syrian refugees n 110 living lebanon completed arabic version international trauma questionnaire measure specifically designed capture symptom content icd11 ptsd cptsd results total 626 sample met diagnostic criteria ptsd cptsd refugees met criteria cptsd 361 ptsd 252 gender differences observed latent class analysis results identified three distinct groups 1 ptsd class 2 cptsd class 3 low symptom class class membership significantly predicted levels functional impairment conclusion support discriminant validity icd11 ptsd cptsd observed first time within sample refugees support crosscultural validity icd11 proposals prevalence ptsd cptsd similar observed culturally distinct contexts
https://doi.org/10.1007/s11999-016-4894-0
Mauricio Santos?Vega|Menno J. Bouma|Vijay Kohli|Mercedes Pascual
Population Density, Climate Variables and Poverty Synergistically Structure Spatial Risk in Urban Malaria in India
2,016
University of Chicago|University of London|London School of Hygiene & Tropical Medicine|Universitat de Barcelona|Smt. N.H.L. Municipal Medical College|University of Chicago
background world rapidly becoming urban global population living cities projected double 2050 increase urbanization poses new challenges spread control communicable diseases malaria particular urban environments create highly heterogeneous socioeconomic environmental conditions affect transmission vectorborne diseases dependent human water storage waste water management interestingly india opposed africa harbors mosquito vector anopheles stephensi thrives manmade environments cities acts vector plasmodium vivax plasmodium falciparum making malaria problem truly urban phenomenon address role determinants withincity spatial heterogeneity incidence patterns vivax malaria draw comparisons results falciparum malaria methodologyprincipal findings statistical analyses phenomenological transmission model applied extensive spatiotemporal dataset cases plasmodium vivax city ahmedabad gujarat india spans 12 years monthly level wards spatial pattern malaria incidence described largely stationary time parasite malaria risk shown associated socioeconomic indicators environmental parameters temperature humidity dynamical perspective inhomogeneous markov chain model used predict vivax malaria risk models account climate factors socioeconomic level population size show highest predictive skill comparison transmission dynamics falciparum malaria reinforces conclusion spatiotemporal patterns risk strongly driven extrinsic factors conclusionsignificance climate forcing socioeconomic heterogeneity act synergistically local scales population dynamics urban malaria city stationarity malaria risk patterns provides basis targeted intervention vector control based transmission hotspots especially relevant p vivax resilient parasite p falciparum due ability relapse operational shortcomings delivering radical cure
https://doi.org/10.2196/15682
Rahul Shidhaye|Vikram Patel
Association of socio-economic, gender and health factors with common mental disorders in women: a population-based study of 5703 married rural women in India
2,010
Public Health Foundation of India|Sangath|London School of Hygiene & Tropical Medicine|Public Health Foundation of India|Sangath|London School of Hygiene & Tropical Medicine
background populationbased studies low middleincome countries described association socioeconomic gender health factors common mental disorders cmds rural women
https://doi.org/10.1002/14651858.cd006207.pub5
Ziyong Sun|Li Zou|Jiajia Zhang|Mo Shengnan|Shuai Shao|Rong Zhong|Juntao Ke|Xuzai Lu|Xiaoping Miao|Ranran Song
Prevalence and Associated Risk Factors of Dyslexic Children in a Middle-Sized City of China: A Cross-Sectional Study
2,013
Huazhong University of Science and Technology|Huazhong University of Science and Technology|University of South Carolina|Wuhan University|Renmin Hospital of Wuhan University|Huazhong University of Science and Technology|Huazhong University of Science and Technology|Huazhong University of Science and Technology|Huazhong University of Science and Technology|Huazhong University of Science and Technology|Huazhong University of Science and Technology
background many discussions dyslexia based studies conducted western countries risk factors dyslexia gender home literacy environment widely accepted based studies however knowledge studies focusing risk factors dyslexia china therefore aim study investigate prevalence dyslexia potential risk factors methods crosssectional study conducted qianjiang city hubei province china two stages sampling strategy applied randomly selected 5 districts 9 primary schools qianjiang total 6350 students participated study 5063 valid student questionnaires obtained final analyses additional questionnaires dyslexia checklist chinese children pupil rating scale used identify dyslexic children chisquare test multivariate logistic regression employed reveal potential risk factors dyslexia results study revealed prevalence dyslexia 39 qianjiang city middlesized city china among dyslexic children gender ratio boys girls nearly 31 according pvalue multivariate logistic regression gender p001 mothers education level p001 learning habits p001 active learning scheduled reading time associated dyslexia conclusion prevalence rate dyslexic children middlesized cities 39 potential risk factors dyslexic children revealed study great impact detecting treating dyslexic children china early possible although studies still needed investigate risk factors dyslexic children china
https://doi.org/10.1371/journal.pntd.0006164
Jill Luoto|Nusrat Najnin|Minhaj Mahmud|Jeff Albert|Mohammad Tarequl Islam|Stephen P. Luby|Leanne Unicomb|David I. Levine
What Point-of-Use Water Treatment Products Do Consumers Use? Evidence from a Randomized Controlled Trial among the Urban Poor in Bangladesh
2,011
RAND Corporation|International Centre for Diarrhoeal Disease Research|Bangladesh Institute of Development Studies|International Centre for Diarrhoeal Disease Research|Retina Institute|International Centre for Diarrhoeal Disease Research|International Centre for Diarrhoeal Disease Research|International Centre for Diarrhoeal Disease Research|University of California, Berkeley
background evidence household pointofuse pou water treatment products reduce enormous burden waterborne illness nevertheless adoption among global poor low little evidence exists methods gave 600 households poor communities dhaka bangladesh randomlyordered twomonth free trials four water treatment products dilute liquid chlorine sodium hypochlorite solution marketed locally water guard sodium dichloroisocyanurate tablets branded aquatabs combined flocculantdisinfectant powdered mixture pur purifier water silvercoated ceramic siphon filter consumers also received education dangers untreated drinking water measured products consumers used selfreports observation filter chlorine tests products also measured drinking waters contamination e coli compared 200 control households findings households reported highest usage filter although product even 30 usage e coli concentrations stored drinking water generally lowest households water guard households selfreported product usage large reductions e coli concentrations product compared controls conclusion traditional arguments low adoption pou products focus affordability consumers lack information germs dangers unsafe water specific products meshing households preferences study provided free trials repeated informational messages explaining dangers untreated water variety product designs low usage products despite efforts makes clear important barriers exist beyond cost information variation among four product designs without better understanding choices aspirations target endusers householdbased water treatment unlikely reduce morbidity mortality substantially urban bangladesh similar populations
https://doi.org/10.1371/journal.pone.0008770
Carlos A. Reyes?Ortiz|María Esther Irigoyen Camacho|Luis F. Amador|Luís Fernando Vélez|Kenneth J. Ottenbacher|Kyriakos S. Markides
The Impact of Education and Literacy Levels on Cancer Screening among Older Latin American and Caribbean Adults
2,007
The University of Texas Medical Branch at Galveston|The University of Texas Medical Branch at Galveston|University of Colorado Denver|University of Colorado Hospital|University of Colorado Health|The University of Texas Medical Branch at Galveston|The University of Texas Health Science Center at San Antonio|The University of Texas Medical Branch at Galveston|The University of Texas Medical Branch at Galveston
background limited information related effects education literacy cancer screening practices among older adults latin american caribbean countries methods determine association education cancer screening use developed crosssectional study using data health wellbeing aging latin america caribbean study sample included 4183 men 6708 women aged 60 years older seven cities outcomes mammogram pap smear use women prostate examination use men within last 2 years results general illiterate lowereducated older men women lowest rates cancer screening use compared highereducated counterparts multivariate logistic models city combined sample six cities showed high education associated higher odds mammogram pap smear women prostate examination men conclusions older adults low educational literacy levels targeted screening programs populations
https://doi.org/10.1371/journal.pntd.0006902
Yuhui Wan|Ruoling Chen|Shuangshuang Ma|Danielle McFeeters|Ying Sun|Jiahu Hao|Fangbiao Tao
Associations of adverse childhood experiences and social support with self-injurious behaviour and suicidality in adolescents
2,018
Anhui Medical University|University of Wolverhampton|University of Wolverhampton|Anhui Medical University|University of Wolverhampton|Anhui Medical University|Anhui Medical University|Anhui Medical University
background little investigation interaction effects adverse childhood experiences aces social support nonsuicidal selfinjury nssi suicidal ideation suicide attempt community adolescent populations gender differences effects aims examine individual interaction effects aces social support nssi suicidal ideation suicide attempt adolescents explore gender differences method schoolbased health survey conducted three provinces china 20132014 total 14 820 students aged 1020 years completed standard questionnaires record details aces social support nssi suicidal ideation suicide attempt results included participants 894 reported one category aces 12month prevalence nssi suicidal ideation suicide attempt 261 175 44 respectively significantly associated increased aces lower social support multiple adjusted odds ratio nssi low versus high social support 227 95 ci 185267 girls 181 95 ci 153214 boys ratio ratio two odds ratios ror 125 p 0037 girls high aces scores 56 moderate low social support also higher risk suicide attempt boys rors 234 184 202 respectively p lt 005 conclusions aces low social support associated increased risk nssi suicidality chinese adolescents strategies improve social support particularly among female adolescents high number aces integral component targeted mental health interventions declaration interest none
https://doi.org/10.2196/17312
Lynn A. G. Ries|Phyllis A. Wingo|Daniel S. Miller|Holly L. Howe|Hannah K. Weir|H. M. Rosenberg|Sally W. Vernon|Kathleen A. Cronin|Brenda K. Edwards
The annual report to the nation on the status of cancer, 1973-1997, with a special section on colorectal cancer
2,000
National Cancer Institute|American Cancer Society|National Center for Chronic Disease Prevention and Health Promotion|Centers for Disease Control and Prevention|North American Association of Central Cancer Registries|National Center for Chronic Disease Prevention and Health Promotion|Centers for Disease Control and Prevention|National Center for Health Statistics|Centers for Disease Control and Prevention|The University of Texas Health Science Center at Houston|National Cancer Institute|National Cancer Institute
background annual report nation addresses progress cancer prevention control us special section colorectal cancer report joint effort american cancer society national cancer institute nci north american association central cancer registries naaccr centers disease control prevention cdc including national center health statistics nchs methods ageadjusted rates based cancer incidence data nci naaccr underlying cause death compiled nchs joinpoint analysis based nci surveillance epidemiology end results seer program incidence rates nchs death rates 19731997 prevalence screening examinations colorectal cancer obtained cdcs behavioral risk factor surveillance system nchss national health interview survey results 19901997 overall cancer incidence death rates declined joinpoint analyses cancer incidence death rates confirmed declines described earlier reports incidence trends colorectal cancer shown recent steep declines whites contrast leveling rates blacks statetostate variations occurred colorectal cancer screening prevalence well incidence death rates conclusions continuing declines overall cancer incidence death rates encouraging however top ten incidence mortality cancer sites continued increase remained level many cancer sites whites lower incidence mortality rates blacks higher rates hispanics asian pacific islanders american indiansalaska natives variations colorectal cancer incidence death rates raceethnicity gender age geographic area may related differences risk factors demographic characteristics screening medical practice new efforts currently underway increase awareness screening benefits treatment colorectal cancer cancer 2000882398424 2000 american cancer society
https://doi.org/10.2196/17362
Pablo Martinez?Devesa|Rafael Perera|Megan Theodoulou|A. W. Waddell
Cognitive behavioural therapy for tinnitus
2,010
John Radcliffe Hospital|University of Oxford|University of Oxford|Great Western Hospital
background update cochrane review originally published issue 1 2007 cochrane library tinnitus auditory perception described experience sound ear head absence external acoustic stimulation cognitive behavioural therapy cbt uses relaxation cognitive restructuring thoughts exposure exacerbating situations order promote habituation may benefit tinnitus patients may treatment associated psychological conditions objectives assess whether cbt effective management patients suffering tinnitus search methods searched cochrane ear nose throat disorders group trials register cochrane central register controlled trials central pubmed embase cinahl web science biosis previews cambridge scientific abstracts psycinfo isrctn additional sources published unpublished trials date recent search 6 may 2010 selection criteria randomised controlled trials patients unilateral bilateral tinnitus main symptom received cognitive behavioural treatment data collection analysis one review author pmd assessed every report identified search strategy three authors pmd aw mt assessed methodological quality applied inclusionexclusion criteria two authors pmd rp extracted data conducted metaanalysis four authors contributed final text review main results eight trials comprising 468 participants included primary outcome subjective tinnitus loudness found evidence difference cbt treatment another intervention yoga education minimal contact education secondary outcomes found evidence quality life scores improved participants tinnitus comparing cbt treatment another intervention education minimal contact education also found evidence depression scores improved comparing cbt treatment found evidence benefit depression scores comparing cbt treatments yoga education minimal contact education adverseside effects reported trial authors conclusions six studies found evidence significant difference subjective loudness tinnitus however found significant improvement depression score six studies quality life decrease global tinnitus severity another five studies suggesting cbt positive effect management tinnitus
https://doi.org/10.1371/journal.pone.0140455
Imelda Coyne|Dónal P O’Mathúna|Faith Gibson|Linda Shields|Edith Leclercq|Greg Sheaf
Interventions for promoting participation in shared decision-making for children with cancer
2,016
Trinity College Dublin|Dublin City University|London South Bank University|Charles Sturt University|Academic Medical Center|Emma Kinderziekenhuis|Trinity College Dublin
background update cochrane systematic review shared decisionmaking smd making published 2013 childrens rights views heard matters affect lives well established since publication un convention treaty 1989 children cancer generally prefer involved decisionmaking consider important opportunity take part decisionmaking concerning health care even endoflife decisions considerable support involving children healthcare decisionmaking level commensurate experience age abilities thus healthcare professionals parents need know involve children decisionmaking interventions effective promoting sdm children cancer objectives examine effects sdm interventions process sdm children cancer aged four 18 years search methods searched following sources review cochrane central register controlled studies central cochrane library 2016 issue 1 pubmed nlm 1946 february 2016 embase ovid 1974 february 2016 cinahl ebsco 1982 february 2016 eric proquest 1966 february 2016 psycinfo ebsco 1806 february 2016 biosis thomson reuters 1980 december 2009 subscription ceased date proquest dissertations theses 1637 february 2016 sociological abstracts proquest 1952 february 2016 addition searched reference lists relevant articles review articles following conference proceedings 2005 including 2015 american academy communication healthcare aach european society medical oncology esmo european cancer organisation ecco european association communication healthcare international conference communication healthcare icch international shared decision making conference isdm annual conference international society paediatric oncology siop annual scientific meeting society medical decision making smdm scanned isrctn international standard randomised controlled trial number register national institutes health nih register ongoing trials 29 february 2016 selection criteria update included randomised controlled trials rcts controlled clinical trials ccts sdm interventions children cancer aged four 18 years types decisions included treatment health care research participation decisions primary outcome sdm measured validated scale data collection analysis two review authors undertook searches three review authors independently assessed studies obtained contacted study authors additional information main results studies met inclusion criteria hence analysis could undertaken authors conclusions conclusions made effects interventions promote sdm children cancer aged four 18 years review highlighted dearth highquality quantitative research interventions promote participation sdm children cancer many potential reasons lack sdm intervention studies children attitudes towards childrens participation slowly changing society changes may take time translated adopted healthcare settings priority may developing interventions promote childrens participation communication interactions since informationsharing prerequisite sdm restricting review rcts limitation extending review nonrandomised studies nrs may produced evidence update included rcts ccts clearly research needed
https://doi.org/10.1371/journal.pone.0189199
Chandan Kumar|Prashant Kumar Singh|Rajesh Kumar
Under-Five Mortality in High Focus States in India: A District Level Geospatial Analysis
2,012
Indian Institute of Technology Roorkee|International Institute for Population Sciences|Tata Institute of Social Sciences
background paper examines controlling biophysical geographical variables including rainfall productivity agricultural lands topographytemperature market access road networks socioeconomic health care indicators help explain variations underfive mortality rate across districts nine high focus states india literature subject inconclusive survey data upon studies child mortality rely rarely include variables measure factors paper introduces variables analysis 284 districts nine high focus states india methodologyprincipal findings information mortality indicator accessed recently conducted annual health survey 2011 socioeconomic geographic variables census 2011 district level household facility survey 200708 department economics statistics divisions concerned states displaying high spatial dependence spatial autocorrelation mortality indicator outcome variable possible predictors used analysis paper uses spatialerror model effort negate reduce spatial dependence model parameters results evince coverage gap index mixed indicator district wise coverage reproductive child health services female literacy urbanization economic status number newborn care provided primary health centers district transpired significant correlates underfive mortality nine high focus states india study identifies three clusters high underfive mortality rate including 30 districts advocates urgent attention conclusion even controlling possible biophysical geographical variables study reveals health program initiatives major role play reducing underfive mortality rate high focus states india
https://doi.org/10.1136/bjophthalmol-2017-311258
Ming-Shinn Lee|Wu Zi-Pei|Leif Svanström|Koustuv Dalal
Cyber Bullying Prevention: Intervention in Taiwan
2,013
National Dong Hwa University|National Dong Hwa University|Karolinska Institutet|Örebro University
background study aimed explore effectiveness cyber bullying prevention webquest course implementation methodologyfindings study adopted quasiexperimental design two classes made total 61 junior high school students seventh grade study subjects comprised 30 students experimental group 31 students control group experimental group received eight sessions total 360 minutes teaching intervention four consecutive weeks control group engage related courses selfcompiled questionnaire students knowledge attitudes intentions toward cyber bullying prevention adopted data analysed generalized estimating equations understand immediate results students knowledge attitudes intentions intervention results show webquest course immediately effectively enhanced knowledge cyber bullying reduced intentions retained effects learning produced significant impact attitude toward cyber bullying conclusionssignificance intervention pilot study effective positive cyber bulling prevention small number students therefore studies large number students long experimental times different areas countries warranted
https://doi.org/10.1111/j.1369-7625.2010.00655.x
Patrick Ip|Frederick Ka Wing Ho|Hung-Kwan So|Dicken Chan|Mandy Ho|Winnie W. Y. Tso|E. Anthony S. Nelson
Socioeconomic Gradient in Childhood Obesity and Hypertension: A Multilevel Population-Based Study in a Chinese Community
2,016
University of Hong Kong|University of Hong Kong|Chinese University of Hong Kong|Chinese University of Hong Kong|University of Hong Kong|University of Hong Kong|Chinese University of Hong Kong
background study aims assess evidence socioeconomic gradients childhood obesity hypertension populationrepresentative sample hong kong china methods data stratified random sampled growth survey collected 20052006 matched population bycensus obesity defined using international obesity task force standard hypertension defined using hong kong norm table family socioeconomic status ses measured maternal education level neighbourhood ses measured median household income neighbourhood multilevel poisson regression models robust standard error used test association body mass indices childrens parents included potential confounders intraschoolneighbourhood correlations adjusted using random factors results totally 14842 children age 619 years included analysis 166 overweight obese children whose mother completed secondary school higher risk childhood obesity rr 141 95 ci 113176 p 0003 hypertension rr 118 95 ci 101136 p 003 meanwhile children lowest neighbourhood ses group higher risk childhood underweight rr 161 95 ci 104249 p 003 overweight rr 135 95 ci 105172 p 002 obesity rr 207 95 ci 111388 p 002 conclusions socioeconomic gradient childhood obesity hypertension existed hong kong one developed cities china results implications policymakers public health experts highlight need monitor trends parts china
https://doi.org/10.1891/ijcbirth-d-20-00029
Aisha T. Langford|Ken Resnicow|Eileen Dimond|Andrea Denicoff|Diane St. Germain|Worta McCaskill?Stevens|Rebecca A. Enos|Angela Carrigan|Kathy Wilkinson|Ronald S. Go
Racial/ethnic differences in clinical trial enrollment, refusal rates, ineligibility, and reasons for decline among patients at sites in the National Cancer Institute's Community Cancer Centers Program
2,013
University of Michigan–Ann Arbor|University of Michigan–Ann Arbor|National Cancer Institute|National Cancer Institute|National Cancer Institute|National Cancer Institute|Emmes (United States)|Frederick National Laboratory for Cancer Research|Billings Clinic|Gundersen Health System
background study examined racialethnic differences among patients clinical trial ct enrollment refusal rates ineligibility desire participate research within national cancer institutes community cancer centers program ncccp clinical trial screening accrual log methods data 4509 log entries evaluated study four logistic regression models run using physicalmedical conditions enrollment ct patient eligible declined ct desire participate research dependent variables results age 65 years 151 95 ci 128179 males 228 95 ci 192271 nonhispanic black race 153 95 ci 12196 significantly associated physicalmedical conditions age 65 years significantly associated lower ct enrollment 083 95 ci 07098 males 078 95 ci 065094 higher grade level score consent form readability 09 95 ci 083097 significantly associated lower refusal rates consent page length 20 significantly associated lower odds desire participate research among ct decliners 075 95 ci 058098 conclusions racialethnic differences ct enrollment refusal rates desire participate research reason given ct refusal higher odds physicalmedical conditions associated older age males nonhispanic blacks better management physicalmedical conditions treatment may increase pool eligible patients cts future work examine role comorbidities sex age consent form characteristics ct participation cancer 2014120877884 2013 american cancer society
https://doi.org/10.1002/cncr.33248
Ariel A. Williamson|Jodi A. Mindell|Harriet Hiscock|Jon Quach
Longitudinal sleep problem trajectories are associated with multiple impairments in child well?being
2,020
University of Pennsylvania|Children's Hospital of Philadelphia|University of Pennsylvania|Saint Joseph's University|Murdoch Children's Research Institute|University of Melbourne|Royal Children's Hospital|Victorian Curriculum and Assessment Authority|University of Melbourne|Murdoch Children's Research Institute
background study examined whether distinct sleep problem trajectories infancy middle childhood associated multiple aspects child wellbeing ages 1011 years methods data first six waves longitudinal study australian children birth cohort 5107 children recruited birth caregivers reported child sleep problems time point combination caregiverreported teacherreported childcompleted tasks used index child wellbeing outcomes ages 1011 years including emotionalbehavioural functioning internalizing externalizing symptoms selfcontrol healthrelated quality life cognitive skills academic achievement results latent class analysis identified five distinct sleep problem trajectories time persistent sleep problems middle childhood 77 sample limited infantpreschool sleep problems 90 increased middle childhood sleep problems 170 mild sleep problems time 144 sleep problems 519 compared sleep problems children persistent sleep problems greatest impairments across outcomes except cognitive skills perceptual reasoning moderate large effect sizes children increased middle childhood sleep problems similarly experienced greater internalizing externalizing symptoms worse quality life academic impairments limited infantpreschool sleep problems mild increases time trajectories also showed internalizing concerns worse caregiverreported quality life although effects smaller sleep trajectories conclusions linkages sleep problems negative child outcomes across domains underscore importance early identification targeted intervention address sleep problems promote child wellbeing
https://doi.org/10.1371/journal.pone.0179647
Rakesh Kumar Singh|Babita Singh|Sharika Mahato
Community knowledge, attitude, and perceived stigma of leprosy amongst community members living in Dhanusha and Parsa districts of Southern Central Nepal
2,019
Patan Academy of Health Sciences|Tribhuvan University Teaching Hospital|Hebrew University of Jerusalem|NLR Nepal
background though nepal declared leprosy elimination 2010 burden constantly rising terai communities past 2 years 3000 new leprosy cases diagnosed annually communitys perception important prevention control leprosy enhancing quality life leprosy patients poor knowledge unfavorable attitude stigma create hindrance leprosy control main objective study assess knowledge attitude stigma leprosy amongst community members living dhanusha parsa districts southern central nepal methods total 423 individuals interviewed using structured questionnaire dhanusha parsa districts data analyzed using descriptive frequency percentage median statistical inferences chisquare test kruskal wallis h test mann whitney u test binary logistic regression using spssvs20 results respondents heard leprosy source information leprosy mainly found health workershospitals 331 626 reported bacteria cause followed myths bad bloodcursehereditybad deeds 36 438 responded leprosy transmitted prolonged close contact leprosy patients 257 reported religious rituals treatment 421 good knowledge 409 favorable attitude good knowledge leprosy highly associated favorable attitude towards leprosy p0001 outcome variables knowledge attitude emic score found highly significant association age sex ethnicity religion education occupation respondents p0001 knowledge leprosy transmission positively associated favorable attitude towards leprosy p0001 conclusions strategizing awareness programmes according sociodemographic characteristics enhancing knowledge regarding leprosy cause symptoms transmission prevention treatment foster positive community attitude towards leprosy affected persons enhancing positive attitude towards leprosy affected persons reduce community stigma thus may increase participation community positive attitude may increase early health seeking behaviour including quality life
https://doi.org/10.1002/14651858.cd002834.pub2
Reta Dewau|Amare Muche|Zinabu Fentaw|Melaku Yalew|Gedamnesh Bitew|Erkihun Tadesse Amsalu|Mastewal Arefaynie|Asnakew Molla Mekonen
Time to initiation of antenatal care and its predictors among pregnant women in Ethiopia: Cox-gamma shared frailty model
2,021
Wollo University|Wollo University|Wollo University|Wollo University|Wollo University|Wollo University|Wollo University|Wollo University
background timely initiating antenatal care anc crucial countries high maternal morbidity mortality however developing countries including ethiopia pregnant mothers time initiate antenatal care wellstudied therefore study aimed assess time first anc predictors among pregnant women ethiopia methods communitybased crosssectional study conducted among 7543 pregnant women ethiopia using ethiopian demographic health survey edhs 2016 data twostage stratified cluster sampling employed kaplanmeier km method used estimate time first antenatal care visit coxgamma shared frailty model applied determine predictors adjusted hazard ratio ahr 95 confidence interval reported effect size model adequacy assessed using coxsnell residual plot statistical significance considered p value lt005 data management analysis stata 14 used results median time first anc 5 months iqr 3 independent predictors time first anc visit primary education ahr 124 95ci 113135 secondary education ahr 12895 ci 111147 higher education ahr 143 119172 compared women formal education media exposure ahr 113 95 ci 103124 early initiation anc increases 25 ahr 125 95 ci 112140 poorer 32 ahr 132 95 ci 117149 middle 37 ahr 137 95 ci 120156 richer 41 ahr 141 95ci 1119167 richest households compared poorest household wealth index living city administration media exposure community women literacy also enabler factors long distance health facility nomadic region residency hindering factors early anc visit conclusions current study revealed womens time first antenatal care visit far late ethiopia compared world health organization recommendation predictors time first anc visit education status women media exposure level household wealth index community women literacy ad distance health facility vital maternal child health policies strategies better directed women development also designing applying interventions intended increase timely initiation anc among pregnantwomen researchers also recommended conducting studies using stronger design like cohort establish temporality reduce biases
https://doi.org/10.2196/18343
Farhana Islam|Rahul Chakrabarti|Silvia Zia Islam|Robert P. Finger|Christine Critchley
Factors Associated with Awareness, Attitudes and Practices Regarding Common Eye Diseases in the General Population in a Rural District in Bangladesh: The Bangladesh Population-based Diabetes and Eye Study (BPDES)
2,015
Swinburne University of Technology|Centre for Eye Research Australia|University of Melbourne|RMIT University|Centre for Eye Research Australia|University of Melbourne|Swinburne University of Technology
background assess awareness attitudes practices associated common eye diseases eye care utilization rural district bangladesh methods data collected using multilevel cluster random sampling technique 3104 adults aged 30 years banshgram union questionnaire assessing awareness attitudes practice diabetes common eye diseases educational attainment socioeconomic status medical history results participants aged 30 89 years mean sd age 51 12 years 65 female majority participants heard cataracts 90 trachoma 86 pterygium 84 yet 4 heard diabetic retinopathy dr 7 glaucoma 8 agerelated macular degeneration amd however 58 participants know vision loss could prevented factors associated lower awareness regarding common eye diseases increasing age lack formal schooling lower socioeconomic status lower proportion 57 people schooling compared attained least secondary school certificate education 72 reported knew vision loss could prevented p0001 overall 51 people heard least six 67 nine items relating awareness common eye diseases included 41 participants aged 65 years older compared 61 aged 3035 years p0001 4 eye check least year higher education better ses associated higher frequency eye checks conclusions rural bangladesh awareness cataract trachoma pterygium good limited relation potentially blinding conditions glaucoma dr amd results show large gap public awareness treatment practices common eye diseases public health promotion designed address knowledge gaps
https://doi.org/10.1348/000709900158065
Ching Yu Cheng|Ke Wang|Tien Yin Wong|Nathan Congdon|Mingguang He|Ya Xing Wang|Tasanee Braithwaite|Robert J. Casson|Maria Vittoria Cicinelli|Aditi Das|Seth Flaxman|Jost B. Jonas|Jill Keeffe|John H. Kempen|Janet Leasher|Hans Limburg|Kovin Naidoo|Konrad Pesudovs|Serge Resnikoff|Alexander Silvester|Nina Tahhan|Hugh R. Taylor|Rupert Bourne
Prevalence and causes of vision loss in East Asia in 2015: magnitude, temporal trends and projections
2,019
Duke-NUS Medical School|Singapore National Eye Center|Singapore Eye Research Institute|Beijing Tongren Hospital|Capital Medical University|Beijing Institute of Neurosurgery|Duke-NUS Medical School|Singapore National Eye Center|Singapore Eye Research Institute|Queen's University Belfast|University of Melbourne|Beijing Tongren Hospital|University College London|Moorfields Eye Hospital|Anglia Ruskin University|Moorfields Eye Hospital NHS Foundation Trust|Royal Adelaide Hospital|Vita-Salute San Raffaele University|Leeds Teaching Hospitals NHS Trust|Imperial College London|Heidelberg University|L V Prasad Eye Institute|University of Pennsylvania|Nova Southeastern University|Africa Health Research Institute|Brien Holden Vision Institute|Royal Liverpool University Hospital|University of Liverpool|Brien Holden Vision Institute|University of Melbourne
background determine prevalence causes blindness vision impairment vi east asia 2015 forecast trend 2020 methods systematic literature review metaanalysis estimated prevalence blindness presenting visual acuity lt360 better eye moderatetosevere vision impairment msvi 360presenting visual acuity lt618 mild vision impairment mild vi 618presenting visual acuity lt612 uncorrected presbyopia 1990 2010 2015 2020 total 44 populationbased studies included results 2015 agestandardised prevalence blindness msvi mild vi uncorrected presbyopia 037 80 uncertainty interval ui 012068 306 80 ui 135516 265 80 ui 092491 3291 80 ui 18724847 respectively east asia cataract leading cause blindness 436 followed uncorrected refractive error 129 glaucoma agerelated macular degeneration corneal diseases trachoma diabetic retinopathy dr leading cause msvi uncorrected refractive error followed cataract agerelated macular degeneration glaucoma corneal disease trachoma dr burden vi due uncorrected refractive error cataracts glaucoma dr continued rise decades reported conclusions addressing public healthcare barriers cataract uncorrected refractive error help eliminate almost 57 blindness cases region therefore public healthcare efforts focused effective screening effective patient education access highquality healthcare
https://doi.org/10.1348/000709910x493080
Laura Helena Andrade|Jordi Alonso|Zeina Mneimneh|J. Elisabeth Wells|Ali Al?Hamzawi|Guilherme Borges|Evelyn J. Bromet|Ronny Bruffærts|Giovanni de Girolamo|Ron de Graaf|Silvia Florescu|Oye Gureje|Hinkov Hr|C Hu|Yueqin Huang|Irving Hwang|Robert Jin|Karam Eg|Viviane Kovess?Masfety|Daphna Levinson|Herbert Matschinger|Siobhan O’Neill|José Posada?Villa|Rajesh Sagar|N A Sampson|Carmen Sasu|Dan J. Stein|Tadashi Takeshima|Maria Carmen Viana|Miguel Xavier|RC Kessler
Barriers to mental health treatment: results from the WHO World Mental Health surveys
2,013
Universidade de São Paulo|Hospital Del Mar|Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública|Municipal Institute for Medical Research|Institute for Development, Research, Advocacy and Applied Care|University of Michigan–Ann Arbor|University of Otago|University of Al-Qadisiyah|Universidad Autónoma Metropolitana|Stony Brook University|State University of New York|KU Leuven|Centro San Giovanni di Dio Fatebenefratelli|Trimbos Institute|National School of Public Health, Management and Professional Development|University of Ibadan|National Center of Public Health and Analyses|Shenzhen KangNing Hospital|Jinzhou Kangning Hospital|Peking University|Peking University Sixth Hospital|Harvard University|Harvard Pilgrim Health Care|Institute for Development, Research, Advocacy and Applied Care|École des Hautes Études en Santé Publique|Université Paris Cité|Israel Ministry of Health|Leipzig University|University of Ulster|Pontificia Universidad Javeriana|All India Institute of Medical Sciences|Harvard University|National School of Public Health, Management and Professional Development|Groote Schuur Hospital|University of Cape Town|National Institute of Mental Health|National Center of Neurology and Psychiatry|Universidade Federal do Espírito Santo|Universidade Nova de Lisboa|Harvard University
background examine barriers initiation continuation mental health treatment among individuals common mental disorders method data world health organization world mental health wmh surveys representative household samples interviewed face face 24 countries reasons initiate continue treatment examined subsample n 636 78 analyzed different levels clinical severity results among dsmiv disorder past 12 months low perceived need common reason initiating treatment common among moderate mild severe cases women younger people disorders likely recognize need treatment desire handle problem ones common barrier among respondents disorder perceived need treatment 638 attitudinal barriers much important structural barriers initiating continuing treatment however attitudinal barriers dominated mildmoderate cases structural barriers severe cases perceived ineffectiveness treatment commonly reported reason treatment dropout 393 followed negative experiences treatment providers 269 respondents severe disorders conclusions low perceived need attitudinal barriers major barriers seeking staying treatment among individuals common mental disorders worldwide apart targeting structural barriers mainly countries poor resources increasing population mental health literacy important endeavor worldwide
https://doi.org/10.7196/ajhpe.2016.v8i1.647
Elizabeth Kvale|Chao?Hui Huang|Karen Meneses|Wendy Demark?Wahnefried|Sejong Bae|Casey Azuero|Maria Pisu|Kerri S. Bevis|Christine S. Ritchie
Patient?centered support in the survivorship care transition: Outcomes from the Patient?Owned Survivorship Care Plan Intervention
2,016
University of Alabama at Birmingham|University of Alabama at Birmingham|University of Alabama at Birmingham|University of Alabama at Birmingham|University of Alabama at Birmingham|University of Alabama|University of Alabama at Birmingham|University of Alabama at Birmingham|University of California, San Francisco
background authors knowledge studies date evaluated effects survivorship care planning care transition process specialty cancer care selfmanagement primary care patient experience health outcomes p atient wned urvivorship ransition c ctivated e mpowe survivors postcare single coaching encounter based chronic care model uses motivational interviewing techniques engage survivors breast cancer current study examined effects postcare intervention patient outcomes care coordination methods total 79 survivors american joint commision cancer tnm system stage 0 iiib breast cancer randomized postcare 40 patients usual care 39 patients patient outcomes assessed using 36item short form health survey sf36 socialrole activities limitations selfefficacy managing chronic disease 6item scale patient activation measureshort form patient health questionnaire depression scale baseline 3month followup care coordination assessed using confirmed primary care physician visits reported discussion survivorship care plan 3month followup logistic linear regression analyses conducted examine effect postcare selected outcomes results participants intervention group versus receiving usual care demonstrated significantly higher selfreported health f statistic 371 363 p 017 lower social role limitations f 370 382 p 014 trend toward greater selfefficacy f 369 251 p 07 three qualityoflife domains reached clinically meaningful improvement 3month followup including physical role p 0009 bodily pain p 03 emotional role p 04 conclusions postcare intervention appeared positive impact patient outcomes demonstrated promise strategy improve survivors experience care coordination health outcomes cancer 2016122323242 2016 american cancer society
https://doi.org/10.1177/1545968317733818
Debbie Chen|David Reyes?Gastelum|Lauren P. Wallner|Maria Papaleontiou|Ann S. Hamilton|Kevin C. Ward|Sarah T. Hawley|Brian J. Zikmund?Fisher|Megan R. Haymart
Disparities in risk perception of thyroid cancer recurrence and death
2,019
University of Michigan–Ann Arbor|University of Michigan–Ann Arbor|University of Michigan–Ann Arbor|University of Michigan–Ann Arbor|University of Southern California|Emory University|University of Michigan–Ann Arbor|University of Michigan–Ann Arbor|University of Michigan–Ann Arbor
background authors knowledge studies regarding risk perception among survivors thyroid cancer scarce methods authors surveyed patients diagnosed differentiated thyroid cancer surveillance epidemiology end results registries georgia los angeles county 2632 patients 63 response rate analytic cohort defined 5 risk disease recurrence mortality 1597 patients patients estimated recurrence mortality risks separately increments 10 endpoints 5 95 outcomes dichotomized reasonably accurate estimates risk perception 5 10 versus overestimation risk perception 20 multivariable logistic regression used identify factors associated risk overestimation relationships overestimation worry quality life evaluated results current study sample 247 patients overestimated recurrence risk 125 overestimated mortality risk lower educational level associated overestimating disease recurrence high school diploma odds ratio 164 95 ci 116231 college 136 95 ci 102181 mortality high school diploma 186 95 ci 118293 risk compared attaining least college degree hispanic ethnicity found associated overestimating recurrence risk 144 95 ci 102203 compared white counterparts worry recurrence death found greater among patients overestimated versus reasonably accurate estimate risk disease recurrence mortality respectively p lt 001 patients overestimated mortality risk also reported decreased physical quality life mean score 431 95 ci 416447 compared general population conclusions less educated patients hispanic patients likely report inaccurate risk perceptions associated worry decreased quality life
https://doi.org/10.1177/0272989x17753392
Mi T. Tran|Matthew B. Jeong|Vickie V. Nguyen|Michael Thanh Sharp|Edgar Yu|Filmer Yu|Elisa K. Tong|Marjorie Kagawa?Singer|Charlene Cuaresma|Angela Sy|Janice Y. Tsoh|Ginny Gildengorin|Susan L. Stewart|Tung T. Nguyen
Colorectal cancer beliefs, knowledge, and screening among Filipino, Hmong, and Korean Americans
2,018
University of California, San Francisco|University of California, San Francisco|University of California, San Francisco|University of California, San Francisco|University of California, San Francisco|University of California, San Francisco|University of California, Davis|University of California, Los Angeles|University of Hawai?i at M?noa|University of Hawaii System|University of Hawai?i at M?noa|University of Hawaii System|University of California, San Francisco|University of California, San Francisco|University of California, San Francisco
background authors knowledge studies date regarding colorectal cancer crc beliefs knowledge screening among multiple asian american populations reported lower crc screening rates compared white individuals current study performed assess knowledge beliefs regarding causes crc prevention factors associated crc screening among 3 asian american groups methods authors conducted inlanguage survey filipino honolulu hawaii hmong sacramento california korean los angeles california americans aged 50 75 years sampled social networks bivariate multivariable analyses conducted assess factors associated crc screening results sample 981 participants 783 female 738 reported limited proficiency english participants aware age 177 family history 363 risk factors crc 62 believed fate caused crc 464 participants knew screening prevented crc 743 filipino 106 hmong 558 korean participants p lt001 approximately twothirds participants reported ever undergone crc screening 760 filipino 720 hmong 514 korean participants p lt001 486 date screening 622 filipino 438 hmong 414 korean participants p lt001 factors found significantly associated ever screening korean compared filipino family history crc health insurance regular source health care knowing fatty diet caused crc believing fate caused crc praying prevented found negatively associated ever screening factors associated date crc screening included born united states family history crc access health care conclusions knowledge regarding causes crc prevention among filipino hmong korean individuals low however health care access knowledge beliefs found key determinant crc screening cancer 201812415529 2018 american cancer society
https://doi.org/10.1177/1090198118798676
Dídac Vidal-Piñeiro|Pablo Martín-Trias|Eider M. Arenaza?Urquijo|Roser Sala?Llonch|Imma C. Clemente|Isaias Mena-Sánchez|Núria Bargalló|Carles Falcón|Álvaro Pascual?Leone|David Bartrés?Faz
Task-dependent Activity and Connectivity Predict Episodic Memory Network-based Responses to Brain Stimulation in Healthy Aging
2,014
Universitat de Barcelona|Universitat de Barcelona|Universitat de Barcelona|Universitat de Barcelona|Universitat de Barcelona|Universitat de Barcelona|Consorci Institut D'Investigacions Biomediques August Pi I Sunyer|Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine|Consorci Institut D'Investigacions Biomediques August Pi I Sunyer|Institut Guttmann|Berenson Allen Center for Noninvasive Brain Stimulation|Beth Israel Deaconess Medical Center|Consorci Institut D'Investigacions Biomediques August Pi I Sunyer|Universitat de Barcelona
background transcranial magnetic stimulation tms affect episodic memory one main cognitive hallmarks aging mechanisms action remain unclear objectives evaluate behavioral functional impact excitatory tms group healthy elders methods applied paradigm repetitive tms intermittent thetaburst stimulation left inferior frontal gyrus healthy elders n 24 evaluated impact performance episodic memory task two levels processing associated brain activity captured pre post fmri scans results posttms fmri found tmsrelated activity increases left prefrontal cerebellumoccipital areas specifically deep encoding shallow encoding rest furthermore found taskdependent change connectivity encoding task cerebellumoccipital areas tmstargeted left inferior frontal region connectivity change correlated tms effects brain networks conclusions results suggest aged brain responds brain stimulation statedependent manner engaged different tasks components tms effect related interindividual connectivity changes measures findings reveal fundamental insights brain network dynamics aging capacity probe combined behavioral stimulation approaches
https://doi.org/10.3390/dj6020011
F. Jackie June ter Heide|Trudy Mooren|Wim Chr. Kleijn|Ad de Jongh|Rolf J. Kleber
EMDR versus stabilisation in traumatised asylum seekers and refugees: results of a pilot study
2,011
Foundation Centrum '45|Foundation Centrum '45|Foundation Centrum '45|University of Amsterdam|Academic Center for Dentistry Amsterdam|Foundation Centrum '45|Utrecht University
background traumatised asylum seekers refugees clinically considered complex population discussion exists whether population treatment guidelines posttraumatic stress disorder ptsd followed traumafocused cognitivebehavioural therapy tfcbt eye movement desensitisation reprocessing emdr applied whether phased model starting stabilisation preferable clinicians fear traumafocused interventions may lead unmanageable distress may ineffective cognitivebehavioural interventions found effective traumatised refugees studies concerning efficacy emdr population conducted yet objective preparation randomised trial comparing emdr stabilisation traumatised refugees pilot study 20 participants conducted objective examine feasibility participation randomised trial complex population examine acceptability preliminary efficacy emdr design participants randomly allocated 11 sessions either emdr stabilisation symptoms ptsd scidi htq depression anxiety hscl25 quality life whoqolbref assessed pre posttreatment 3month followup results participation traumatised refugees study found feasible although issues associated complex traumatisation led high pretreatment attrition challenges assessments acceptability emdr found equal stabilisation high dropout conditions participants dropped emdr condition unmanageable distress improvement emdr participants small emdr found less efficacious stabilisation different symptom courses two conditions emdr showing improvement stabilisation showing deterioration pretreatment posttreatment justify conduct full trial conclusion adaptations study design inclusion greater sample justifiable determine treatment suitable complex populationfor abstract full text languages please see supplementary files reading tools online
https://doi.org/10.33607/bjshs.v2i113.787
Jasvinder A. Singh|Liana Fraenkel|Candace Green|Graciela S. Alarcón|Jennifer Barton|Kenneth G. Saag|Leslie Hanrahan|Sandra Raymond|Robert P. Kimberly|Amye Leong|Elyse Reyes|Richard L. Street|María E. Suarez?Almazor|Guy S. Eakin|Laura Marrow|Charity Morgan|Brennda Caro|Jeffrey A. Sloan|Bochra Jandali|Salvador Garcia|Jennifer M. Grossman|Kevin Winthrop|Laura Trupin|Maria Dall’Era|Alexa Meara|Tara Rizvi|W. Winn Chatham|Jinoos Yazdany
Individualized decision aid for diverse women with lupus nephritis (IDEA-WON): A randomized controlled trial
2,019
University of Alabama at Birmingham|Birmingham VA Medical Center|Yale University|University of Alabama at Birmingham|University of Alabama at Birmingham|VA Portland Health Care System|Oregon Health & Science University|University of Alabama at Birmingham|Lupus Foundation of America|Lupus Foundation of America|University of Alabama at Birmingham|Healthy Start|Texas A&M University|The University of Texas MD Anderson Cancer Center|Arthritis Foundation|Arthritis Foundation|University of Alabama at Birmingham|Georgia State University|Mayo Clinic|Baylor College of Medicine|Baylor College of Medicine|University of California, Los Angeles|Oregon Health & Science University|University of California, San Francisco|University of California, San Francisco|The Ohio State University|Baylor College of Medicine|University of Alabama at Birmingham|University of California, San Francisco
background treatment decisionmaking regarding immunosuppressive therapy challenging individuals lupus assessed effectiveness decision aid immunosuppressive therapy lupus nephritis methods findings united states multicenter openlabel randomized controlled trial rct adult women lupus nephritis mostly racialethnic minority backgrounds low socioeconomic status ses seen outpatient settings randomized individualized culturally tailored computerized decision aid versus american college rheumatology acr lupus pamphlet 11 ratio using computergenerated randomization hypothesized coprimary outcomes decisional conflict informed choice regarding immunosuppressive medications would improve decision aid group 301 randomized women 298 analyzed 47 africanamerican 26 hispanic 15 white mean age standard deviation sd 37 12 years 57 annual income 40000 36 high school education less compared provision acr lupus pamphlet n 147 participants randomized decision aid n 151 1 clinically meaningful statistically significant reduction decisional conflict 218 standard error se 25 versus 127 se 20 p 0005 2 difference informed choice main analysis 41 versus 31 p 008 clinically meaningful statistically significant difference sensitivity analysis net values immunosuppressives positive favor versus negative 50 versus 35 p 0006 unresolved decisional conflict lower decision aid versus pamphlet groups 22 versus 44 p 0001 significantly patients decision aid versus pamphlet group rated information excellent understanding lupus nephritis 49 versus 33 risk factors 43 versus 27 medication options 50 versus 33 p 0003 ease use materials higher decision aid versus pamphlet groups 51 versus 38 p 0006 key study limitations exclusion men short followup lack clinical outcomes including medication adherence conclusions individualized decision aid effective usual care reducing decisional conflict choice immunosuppressive medications women lupus nephritis trial registration clinicaltrialsgov nct02319525
https://doi.org/10.1086/514823
Srinath Satyanarayana|Sreenivas Achuthan Nair|Sarabjit Chadha|Roopa Shivashankar|Gopal Sharma|Subhash Yadav|S. Mohanty|Vishnuvardhan Kamineni|Nevin Wilson|Anthony Harries|Puneet Dewan
From Where Are Tuberculosis Patients Accessing Treatment in India? Results from a Cross-Sectional Community Based Survey of 30 Districts
2,011
International Union Against Tuberculosis and Lung Disease|Centre for Chronic Disease Control|London School of Hygiene & Tropical Medicine|International Union Against Tuberculosis and Lung Disease|World Health Organization - India
background tuberculosis tb notification india revised national tb control programme rntcp provides information tb patients registered treatment programme limited information proportion patients treated tb outside rntcp patients access treatment objectives estimate proportion patients accessing tb treatment outside rntcp identify basic demographic characteristics methods cross sectional communitybased survey 30 districts patients identified doortodoor survey interviewed using semistructured questionnaire results estimated 75000 households enumerated 73249 households 976 visited 371174 household members 761 tb patients identified 205 cases per 100000 populations data collected 609 80 tb patients 331 54 95 ci 4266 determined taking treatment dotsrntcp remaining 278 46 95 ci 3457 treatment outside dotsrntcp sources hence unlikely part tb notification system patients accessing treatment outside dotsrntcp likely patients rural areas adjusted odds ratio aor 25 95 ci 1253 whose tb diagnosed nongovernment health facility aor 140 95 ci 79249 conclusions communitybased survey found nearly half selfreported tb patients missed tb notification system districts study highlights need 1 reviewing revising scope tb notification system 2 strengthening monitoring health care delivery systems periodic assessment reach utilisation rntcp services especially among rural communities 3 advocacy communication social mobilisation activities focused rural communities low household incomes 4 inclusive involvement healthcare providers especially providers poor rural communities
https://doi.org/10.1080/08858190802665245
Ricardo A. A. Ximenes|Maria de Fátima Pessoa Militão de Albuquerque|Wayner Vieira de Souza|Ulísses Ramos Montarroyos|George Tadeu Nunes Diniz|Carlos Feitosa Luna|Laura C. Rodrigues
Is it better to be rich in a poor area or poor in a rich area? A multilevel analysis of a case-control study of social determinants of tuberculosis
2,009
Universidade Federal de Pernambuco|Universidade de Pernambuco|Fundação Oswaldo Cruz|Universidade Federal de Pernambuco|Fundação Oswaldo Cruz|Universidade Federal de Pernambuco|Fundação Oswaldo Cruz|Fundação Oswaldo Cruz|London School of Hygiene & Tropical Medicine
background tuberculosis known socioeconomic determinants individual area levels known whether independent whether interact relative contributions burden tuberculosis
https://doi.org/10.2105/ajph.2017.304180
Jason L. Vassy|Kelsey O?Brien|Jessica L. Waxler|Elyse R. Park|Linda M. Delahanty|José C. Florez|James B. Meigs|Richard W. Grant
Impact of Literacy and Numeracy on Motivation for Behavior Change After Diabetes Genetic Risk Testing
2,012
Massachusetts General Hospital|Harvard University|Center for Human Genetics|Massachusetts General Hospital|Harvard University|Center for Human Genetics|Massachusetts General Hospital|Harvard University|Center for Human Genetics|Massachusetts General Hospital|Harvard University|Center for Human Genetics|Massachusetts General Hospital|Harvard University|Center for Human Genetics|Massachusetts General Hospital|Harvard University|Center for Human Genetics|Massachusetts General Hospital|Harvard University|Center for Human Genetics|Massachusetts General Hospital|Harvard University|Center for Human Genetics
background type 2 diabetes genetic risk testing might motivate atrisk patients adopt diabetes prevention behaviors however influence literacy numeracy patient response diabetes genetic risk unknown objective authors investigated association health literacy genetic literacy health numeracy patient responses diabetes genetic risk design measurements overweight patients high phenotypic risk type 2 diabetes recruited clinical trial diabetes genetic risk testing baseline participants predicted motivation lifestyle modification prevent diabetes might change response hypothetical scenarios receiving high low genetic risk results responses analyzed according participants health literacy genetic literacy health numeracy results twothirds 67 participants n 175 reported high motivation prevent diabetes despite high health literacy 92 high school level many participants limited health numeracy 30 genetic literacy 38 almost 98 reported highrisk genetic results would increase motivation lifestyle modification contrast response lowrisk genetic results varied higher levels health literacy p 004 genetic literacy p 002 health numeracy p 002 associated anticipated decrease motivation lifestyle modification response lowrisk results conclusions patients reported highrisk genetic results would motivate adopt healthy lifestyle changes response lowrisk results varied patient numeracy literacy however anticipated responses may correlate true behavior change future research justifies clinical use genetic testing motivate behavior change may important assess patient characteristics modify motivational effect
https://doi.org/10.1155/2013/580596
Tanja A. J. Houweling|Anton E. Kunst|Caspar W. N. Looman|Johan P. Mackenbach
Determinants of under-5 mortality among the poor and the rich: a cross-national analysis of 43 developing countries
2,005
Erasmus MC|Erasmus MC|Erasmus MC|Erasmus MC
background under5 mortality unacceptably high many countries burden mainly borne poor whereas country characteristics known influence under5 mortality unknown whether different impact poor rich aimed describe association under5 mortality socioeconomic political health care factors varies strength richer poorer children
https://doi.org/10.1155/2017/8516843
Rachel A. Freedman|Elena M. Kouri|Dee W. West|Nancy L. Keating
Racial/ethnic disparities in knowledge about one's breast cancer characteristics
2,015
Dana-Farber Cancer Institute|Harvard University|Public Health Institute|Harvard University|Brigham and Women's Hospital
background understanding tumor characteristics likely important little known breast cancer patients knowledge disease authors assessed womens knowledge tumor characteristics whether racialethnic disparities knowledge exist whether education health literacy influence associations methods populationbased cohort women northern california stage 0 iii breast cancers diagnosed 2010 2011 participation rate 685 surveyed among 500 respondents 222 nonhispanic white women 142 nonhispanic black women 136 hispanic women racialethnic differences knowledge tumor characteristics estrogen receptor er status human epidermal growth factor receptor 2 her2 status stage grade correctness tumor information california cancer registry data confirmation examined multivariate logistic regression used assess probability 1 knowing tumor stage receptor status grade 2 correctly answering questions tumor information raceethnicity impact education health literacy findings examined sequential models results overall 32 82 women reported knowing 4 tumor characteristics interest 20 58 correctly reported characteristics adjustment black hispanic women less likely white women know correct responses stage er status her2 status p lt05 education health literacy significantly associated knowing correct information characteristics variables eliminate racialethnic differences observed conclusions patients knowledge breast cancer generally poor particularly minority women study knowledge may impact receipt care outcomes warranted cancer 2015121724732 2014 american cancer society
https://doi.org/10.1542/peds.2004-2164
Tizta Tilahun Degfie|Gily Coene|Stanley Luchters|Wondwosen Kassahun|Els Leye|Marleen Temmerman|Olivier Degomme
Family Planning Knowledge, Attitude and Practice among Married Couples in Jimma Zone, Ethiopia
2,013
Jimma University|Ghent University Hospital|Burnet Institute|Monash University|Jimma University|Ghent University Hospital|Ghent University Hospital|Ghent University Hospital
background understanding people use family planning critical address unmet needs increase contraceptive use according ethiopian demographic health survey 2011 women men knowledge family planning methods 29 married women using contraceptives 20 women unmet need family planning examined knowledge attitudes contraceptive practice well factors related contraceptive use jimma zone ethiopia methods data collected march may 2010 among 854 married couples using multistage sampling design quantitative data based semistructured questionnaires triangulated qualitative data collected focus group discussions compared proportions performed logistic regression analysis result concept family planning well known studied population sexstratified analysis showed pills injectables commonly known sexes longterm contraceptive methods better known women traditional methods well emergency contraception men formal education important factor associated better knowledge contraceptive methods aor 207 p0001 particular among women aorwomen 277 vs aormen 149 p0001 general 4 811 men ever used contraception 64 43 females ever used currently using contraception respectively conclusion high knowledge contraceptives match high contraceptive practice study area study demonstrates mere physical access proximity clinics family planning awareness contraceptives sufficient ensure contraceptive needs met thus projects aiming increasing contraceptive use contemplate establish better counseling contraceptive side effects method switch furthermore family planning activities wives husbands participation considered
https://doi.org/10.1093/cid/cis753
Kevin Croke|Rifat Atun
The long run impact of early childhood deworming on numeracy and literacy: Evidence from Uganda
2,019
Harvard Global Health Institute|Harvard Global Health Institute
background 145 billion people currently suffer soil transmitted helminth infection largest burden occurring africa asia safe cost effective deworming treatment exists debate mass distribution treatment high prevalence settings world health organization recommends mass administration anthelmintic drugs preschool schoolaged children high 20 prevalence settings several long run follow studies influential trial suggested large benefits persist time recent systematic reviews called recommendation question methods findings paper analyzes longterm impact clusterrandomized trial eastern uganda provided mass deworming treatment preschool aged children 2000 2003 numeracy literacy skills children young adults living villages 20102015 study uses numeracy literacy data collected seven twelve years end deworming trial randomly selected subset communities original trial educationfocused survey relationship deworming study building earlier working paper used data 2010 2011 survey rounds paper uses additional four years numeracy literacy data 2012 2013 2014 2015 aggregating data survey rounds difference numeracy scores treatment versus control communities 007 standard deviations sd 95 ci 010 024 p 040 difference literacy scores 005 sd 95 ci 016 027 p 062 difference total scores 007 sd 95 ci 011 025 p 044 significant differences program impact gender numeracy literacy differentially positively affected girls age treatment effects larger primary school aged subsample also significant treatment interactions living households treatmenteligible children evidence differential treatment effects age program eligibility number years program eligibility conclusions mass deworming preschool aged children high prevalence communities uganda resulted statistically significant gains numeracy literacy 712 years program completion point estimates positive imprecise study lacked sufficient power rule substantial positive effects modest negative effects however suggestive evidence deworming relatively beneficial girls primary school aged children children living households treated children research approval analysis conducted secondary data publicly available research approval sought received individual records anonymized data provider prior public release
https://doi.org/10.1177/0272989x10369007
Ilaria Montagni|Inass Mabchour|Christophe Tzourio
Digital Gamification to Enhance Vaccine Knowledge and Uptake: Scoping Review
2,020
University of Bordeaux|Bordeaux Population Health|Inserm|Université des Antilles|Inserm|University of Bordeaux|Bordeaux Population Health
background vaccine hesitancy growing threat population health effective interventions needed reduce frequency digital gamification promising new approach tackle public health issue objective purpose scoping review assess amount quality outcomes studies evaluating gamified digital tools created increase vaccine knowledge uptake methods searched peerreviewed articles published july 2009 august 2019 pubmed google scholar journal medical internet research psycinfo psycarticles psychology behavioral sciences collection socindex studies coded author year publication country journal research design sample size characteristics type vaccine theory used game content game modality gamification elements data analysis type outcomes mean quality score outcomes synthesized textual narrative synthesis method results total 7 articles met inclusion criteria critically reviewed game modalities gamification elements diverse role play reward system present studies articles included mixture randomized controlled trials quasiexperimental studies studies comprising quantitative qualitative measures majority studies theorydriven identified gamified digital tools highly appreciated usability effective increasing awareness vaccine benefits motivation vaccine uptake conclusions despite relative paucity studies topic scoping review suggests digital gamification strong potential increasing vaccination knowledge eventually vaccination coverage
https://doi.org/10.1177/0272989x14553472
Adrian Wolfensberger|Philippe Vuistiner|Michel Konzelmann|Chantal Plomb-Holmes|Bertrand Léger|François Lüthi
Clinician and Patient-reported Outcomes Are Associated With Psychological Factors in Patients With Chronic Shoulder Pain
2,016
University of Lausanne|Clinique Romande de Réadaptation|Clinique Romande de Réadaptation|Clinique Romande de Réadaptation|Clinique Romande de Réadaptation|University of Lausanne
background validated clinician outcome scores considered less associated psychosocial factors patientreported outcome measurements proms belief may lead misconceptions instruments related similar factors questions asked patients chronic shoulder pain biopsychosocial factors associated 1 proms 2 clinicianrated outcome measurements methods new patients ages 18 65 chronic shoulder pain unilateral shoulder injury admitted swiss rehabilitation teaching hospital may 2012 january 2015 screened potential contributing biopsychosocial factors study period 314 patients screened applying prespecified criteria 158 patients evaluated median symptom duration 9 months interquartile range 5515 months 72 patients 114 patients rotator cuff tears work injuries 59 93 patients followed mean 316 days sd 75 days exclusion criteria concomitant injuries another location major minor upper limb neuropathy inability understand validated available versions proms proms dash brief pain inventory patient global impression change treatment physiotherapy cognitive therapy vocational training constantmurley score used clinicianrated outcome measurement statistical models used estimate associations biopsychosocial factors outcomes results greater disability dash associated psychological factors hospital anxiety depression scale pain catastrophizing scale combined coefficient 064 95 ci 025103 p 0002 social factors language professional qualification combined coefficient 615 95 ci 1109 122 p 0015 greater pain brief pain inventory associated psychological factors hospital anxiety depression scale pain catastrophizing scale combined coefficient 0076 95 ci 0021013 p 0006 poorer impression change associated psychological factors hospital anxiety depression scale pain catastrophizing scale tampa scale kinesiophobia coefficient 093 95 ci 087099 p 0026 social factors education language professional qualification coefficient 667 95 ci 2771610 p 0001 worse clinicianrated outcome associated psychological factors hospital anxiety depression scale depression pain catastrophizing scale tampa scale kinesiophobia combined coefficient 035 95 ci 058 012 p 0003 conclusions depressive symptoms catastrophizing appear key factors influencing proms clinicianrated outcomes study suggests revisiting constantmurley score level evidence level iii prognostic study
https://doi.org/10.2105/ajph.2016.303180
Cindie Slightam|Amy J. P. Gregory|Junjie Hu|Josephine Jacobs|Tolessa Gurmessa|Rachel Kimerling|Daniel M. Blonigen|Donna M. Zulman
Patient Perceptions of Video Visits Using Veterans Affairs Telehealth Tablets: Survey Study
2,020
VA Palo Alto Health Care System|Center for Innovation|VA Palo Alto Health Care System|Center for Innovation|Stanford University|VA Palo Alto Health Care System|Center for Innovation|VA Palo Alto Health Care System|Center for Innovation|United States Department of Veterans Affairs|Veterans Health Administration|VA Palo Alto Health Care System|Center for Innovation|National Center for Post Traumatic Stress Disorder|VA Palo Alto Health Care System|Center for Innovation|VA Palo Alto Health Care System|Center for Innovation|Stanford University|VA Palo Alto Health Care System|Center for Innovation
background videobased health care help address access gaps patients rapidly offered health care organizations however patients lack access technology may left behind initiatives 2016 us department veterans affairs va began distributing videoenabled tablets provide video visits veterans health care access barriers objective study aimed evaluate veterans experiences vaissued tablets identify patient characteristics associated preferences video visits vs inperson care methods baseline survey sent tablet recipients followup survey sent respondents 3 6 months later multivariate logistic regression used identify patient characteristics associated preferences care examined qualitative themes around care preferences using standard content analysis methods coding data collected openended questions results patientreported access barriers centered around transportation healthrelated challenges outside commitments feeling uncomfortable uneasy va satisfaction tablet program high followup survey approximately twothirds tablet recipients preferred care via tablet 194604 321 expressed videobased inperson care 216604 357 whereas onethird 192604 317 indicated preference inperson care patients significantly likely report preference video visits vs preference inperson visits rating felt uncomfortable va setting reported collaborative communication style doctor substance use disorder diagnosis lived place better broadband coverage patients less likely report preference video visits chronic conditions qualitative analyses identified four themes related preferences videobased care perceived improvements access care perceived differential quality care feasibility obtaining necessary care technologyrelated challenges conclusions many recipients vaissued tablets report video care equivalent preferred inperson care results may inform efforts identify good candidates virtual care interventions support individuals experience technical challenges
https://doi.org/10.1093/fampra/cmp060
Tom Jefferson|Chris B Del Mar|Liz Dooley|Eliana Ferroni|Lubna A. Al?Ansary|Ghada Bawazeer|Mieke van Driel|Mark Jones|Sarah Thorning|Elaine Beller|Justin Clark|Tammy Hoffmann|Paul Glasziou|John Conly
Physical interventions to interrupt or reduce the spread of respiratory viruses
2,020
University of Oxford|Bond University|Bond University|Regione del Veneto|King Saud University|King Saud University|University of Queensland|Ghent University|Bond University|Gold Coast Hospital|Bond University|Bond University|Bond University|Bond University|Alberta Health Services|Foothills Medical Centre|University of Calgary
background viral epidemics pandemics acute respiratory infections aris pose global threat examples influenza h1n1 caused h1n1pdm09 virus 2009 severe acute respiratory syndrome sars 2003 coronavirus disease 2019 covid19 caused sarscov2 2019 antiviral drugs vaccines may insufficient prevent spread update cochrane review published 2007 2009 2010 2011 evidence summarised review include results studies current covid19 pandemic objectives assess effectiveness physical interventions interrupt reduce spread acute respiratory viruses search methods searched central pubmed embase cinahl 1 april 2020 searched clinicaltrialsgov ictrp 16 march 2020 conducted backwards forwards citation analysis newly included studies selection criteria included randomised controlled trials rcts clusterrcts trials investigating physical interventions screening entry ports isolation quarantine physical distancing personal protection hand hygiene face masks gargling prevent respiratory virus transmission previous versions review also included observational studies however update sufficient rcts address study aims data collection analysis used standard methodological procedures expected cochrane used grade assess certainty evidence three pairs review authors independently extracted data using standard template applied previous versions review revised reflect focus rcts clusterrcts update contact trialists missing data due urgency completing review extracted data adverse events harms associated interventions main results included 44 new rcts clusterrcts update bringing total number randomised trials 67 included studies conducted covid19 pandemic six ongoing studies identified three evaluating masks conducted concurrent covid pandemic one completed many studies conducted nonepidemic influenza periods several studies conducted global h1n1 influenza pandemic 2009 others epidemic influenza seasons 2016 thus studies conducted context lower respiratory viral circulation transmission compared covid19 included studies conducted heterogeneous settings ranging suburban schools hospital wards highincome countries crowded inner city settings lowincome countries immigrant neighbourhood highincome country compliance interventions low many studies risk bias rcts clusterrcts mostly high unclear medicalsurgical masks compared masks included nine trials eight clusterrcts comparing medicalsurgical masks versus masks prevent spread viral respiratory illness two trials healthcare workers seven community low certainty evidence nine trials 3507 participants wearing mask may make little difference outcome influenzalike illness ili compared wearing mask risk ratio rr 099 95 confidence interval ci 082 118 moderate certainty evidence wearing mask probably makes little difference outcome laboratoryconfirmed influenza compared wearing mask rr 091 95 ci 066 126 6 trials 3005 participants harms rarely measured poorly reported two studies covid19 plan recruit total 72000 people one evaluates medicalsurgical masks n 6000 published annals internal medicine 18 nov 2020 one evaluates cloth masks n 66000 n95p2 respirators compared medicalsurgical masks pooled trials comparing n95p2 respirators medicalsurgical masks four healthcare settings one household setting uncertainty effects n95p2 respirators compared medicalsurgical masks outcomes clinical respiratory illness rr 070 95 ci 045 110 lowcertainty evidence 3 trials 7779 participants ili rr 082 95 ci 066 103 lowcertainty evidence 5 trials 8407 participants evidence limited imprecision heterogeneity subjective outcomes use n95p2 respirator compared medicalsurgical mask probably makes little difference objective precise outcome laboratoryconfirmed influenza infection rr 110 95 ci 090 134 moderatecertainty evidence 5 trials 8407 participants restricting pooling healthcare workers made difference overall findings harms poorly measured reported discomfort wearing medicalsurgical masks n95p2 respirators mentioned several studies one ongoing study recruiting 576 people compares n95p2 respirators medical surgical masks healthcare workers covid19 hand hygiene compared control settings included schools childcare centres homes offices comparison hand hygiene interventions control intervention 16 relative reduction number people aris hand hygiene group rr 084 95 ci 082 086 7 trials 44129 participants moderatecertainty evidence suggesting probable benefit considering strictly defined outcomes ili laboratoryconfirmed influenza estimates effect ili rr 098 95 ci 085 113 10 trials 32641 participants lowcertainty evidence laboratoryconfirmed influenza rr 091 95 ci 063 130 8 trials 8332 participants lowcertainty evidence suggest intervention made little difference pooled 16 trials 61372 participants composite outcome ari ili influenza study contributing comprehensive outcome reported pooled data showed hand hygiene may offer benefit 11 relative reduction respiratory illness rr 089 95 ci 084 095 lowcertainty evidence high heterogeneity trials measured reported harms two ongoing studies handwashing interventions 395 children outside covid19 identified one rct quarantinephysical distancing company employees japan asked stay home household members ili symptoms overall fewer people intervention group contracted influenza compared workers control group 275 versus 318 hazard ratio 080 95 ci 066 097 however stayed home infected family members 217 times likely infected found rcts eye protection gowns gloves screening entry ports authors conclusions high risk bias trials variation outcome measurement relatively low compliance interventions studies hamper drawing firm conclusions generalising findings current covid19 pandemic uncertainty effects face masks lowmoderate certainty evidence means confidence effect estimate limited true effect may different observed estimate effect pooled results randomised trials show clear reduction respiratory viral infection use medicalsurgical masks seasonal influenza clear differences use medicalsurgical masks compared n95p2 respirators healthcare workers used routine care reduce respiratory viral infection hand hygiene likely modestly reduce burden respiratory illness harms associated physical interventions underinvestigated need large welldesigned rcts addressing effectiveness many interventions multiple settings populations especially risk aris
https://doi.org/10.1177/0272989x18776637