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Fiona Lobban|Duncan Appelbe|Victoria Appleton|Golnar Aref-Adib|Johanna Barraclough|Julie Billsborough|Naomi Fisher|Sheena Foster|Bethany Gill|David Glentworth|Chris Harrop|Sonia Johnson|Steven Jones|Tibor Zoltan Kovacs|Elizabeth Lewis|Barbara Mezes|Charlotte Morton|Elizabeth Murray|Puffin O’Hanlon|Vanessa Pinfold|Jo Rycroft?Malone|Ronald Siddle|Jo Smith|Chris Sutton|Pietro Viglienghi|A. Earl Walker|Catherine Wintermeyer
An online supported self-management toolkit for relatives of people with psychosis or bipolar experiences: the IMPART multiple case study
2,020
Lancaster University|University of Liverpool|Lancaster University|University College London|Lancaster University|McPin Foundation|Lancaster University|McPin Foundation|Lancaster University|University College London|Lancaster University|Lancaster University|Lancaster University|University College London|University College London|University College London|McPin Foundation|Bangor University|University of Worcester|Manchester Academic Health Science Centre|University of Manchester|Lancaster University|Lancaster University
background digital health interventions potential improve delivery psychoeducation people mental health problems relatives despite substantial investment development digital health interventions successful implementation routine clinical practice rare objectives use implementation relatives education coping toolkit react psychosisbipolar disorder identify critical factors affecting uptake use develop implementation plan support delivery react design implementation study using mixedmethods theorydriven multiple case study approach studyspecific implementation theory react based normalisation process theory developed tested iterations implementation plan address key factors affecting implementation developed setting earlyintervention teams six nhs mental health trusts england three north three south participants total 281 staff accounts 159 relatives accounts created 129 staff 23 relatives took part qualitative interviews experiences 132 relatives provided demographic data 56 provided baseline data 21 provided data 12 weeks followup 20 provided data 24 weeks followup interventions react online supported selfmanagement toolkit offering 12 evidencebased psychoeducation modules support via forum confidential direct messaging service relatives people psychosis bipolar disorder implementation intervention developed staff iteratively adapted address identified barriers adaptations included modifications toolkit delivered teams main outcome measures main outcome factors affecting implementation react assessed primarily indepth interviews staff relatives also assessed quantitative measures delivery staff accounts relatives invitations use react relatives logins time spent website impact react relatives distress general health questionnaire28 carer wellbeing support carer wellbeing support scale questionnaire results staff relatives generally positive content react seeing valuable resource could help services improve support meet clinical targets within comprehensive service included facetoface support additional content barriers implementation included high staff caseloads difficulties prioritising supporting relatives technical difficulties using react poor interoperability trust information technology systems care pathways lack access mobile technology information technology training restricted forum populations leading low levels use staff fears managing risk online trolling replacement technology uncertainty around reacts longterm availability evidence react would reduce staff time supporting relatives already low might increase facilitating communication 281 staff accounts created 57 staff sent relatives invitations total 355 relatives invitations sent 310 unique relatives leading creation 159 relatives accounts mean number logins relatives 378 standard deviation 443 wide variation 0 31 median 2 interquartile range 18 mean total time spent website 406 minutes standard deviation 5454 minutes range 0298 minutes median 201 minutes interquartile range 49575 minutes pattern declining mean scores distress social dysfunction depression anxiety insomnia increases relatives wellbeing ehealth literacy changes statistically significant conclusions digital health interventions react iteratively developed evaluated adapted implemented staff service user input part longterm strategy develop integrated technologyenabled services implementation strategies must instil sense ownership staff ensure adequate training risk protocols resources deliver technology costeffectiveness impact workload inequalities accessing health care need testing along generalisability findings digital health interventions limitations react offered team running implementation relatives toolkit impart study perceived staff relatives timelimited research study rather ongoing clinical service affected engagement access observational data limited trial registration current controlled trials isrctn16267685 funding project funded national institute health research nihr health services delivery research programme published full health services delivery research vol 8 37 see nihr journals library website project information
https://doi.org/10.1371/journal.pntd.0000683
Felix Machleid|Robert Kaczmarczyk|Doreen Johann|Justinas Bal?i?nas|Beatriz Atienza-Carbonell|Finn von Maltzahn|Lina Mosch
Perceptions of Digital Health Education Among European Medical Students: Mixed Methods Survey
2,020
Technical University of Munich|Technical University of Munich|Humboldt-Universität zu Berlin|Lithuanian University of Health Sciences|Universitat de València|RWTH Aachen University|Charité - Universitätsmedizin Berlin|Humboldt-Universität zu Berlin|Freie Universität Berlin
background digital health technologies hold promise enhance patientrelated outcomes support health care staff reducing workload improve coordination care key users digital health technologies health care workers crucial enable meaningful digital transformation health care digital health literacy digital skills become prerequisite competencies health professionals facilitate implementation leverage potential digital technologies improve health objective aimed assess european medical students perceived knowledge opinions toward digital health status digital health implementation medical education students pressing needs methods explanatory design mixed methods study based online anonymous selfadministered survey targeted toward european medical students linear regression analysis used identify influence year medical studies responses additional analysis performed grouping responses selfevaluated frequency ehealth technology use written responses four qualitative questions survey analyzed using inductive approach results survey received total 451 responses 39 european countries respondents every year medical studies majority respondents saw advantages use digital health 406 183451 felt prepared work digitized health care system half 240451 532 evaluated ehealth skills poor poor medical students considered lack education reason 849 383451 agreeing strongly agreeing digital health education implemented medical curriculum students demanded introductory specific ehealth courses covering data management ethical aspects legal frameworks research entrepreneurial opportunities role public health health systems communication skills practical training emphasis lay tailoring learning future job requirements interprofessional education conclusions study shows lack digital healthrelated formats medical education perceived lack digital health literacy among european medical students findings indicate gap willingness medical students take active role becoming key players digital transformation health care education receive faculties
https://doi.org/10.2196/18799
Zsombor Zrubka|Óscar Brito Fernandes|Petra Baji|Ottó Hajdú|Levente Kovács|Dionne Kringos|Niek Klazinga|László Gulàcsi|Valentin Brodszky|Fanni Rencz|Márta Péntek
Exploring eHealth Literacy and Patient-Reported Experiences With Outpatient Care in the Hungarian General Adult Population: Cross-Sectional Study
2,020
Óbuda University|Corvinus University of Budapest|Public Health Service of Amsterdam|Amsterdam University Medical Centers|University of Amsterdam|Corvinus University of Budapest|Corvinus University of Budapest|Eötvös Loránd University|Óbuda University|Public Health Service of Amsterdam|Amsterdam University Medical Centers|University of Amsterdam|Public Health Service of Amsterdam|Amsterdam University Medical Centers|University of Amsterdam|Óbuda University|Corvinus University of Budapest|Corvinus University of Budapest|Hungarian Academy of Sciences|Corvinus University of Budapest|Corvinus University of Budapest
background digital health encompasses use information communications technology support health key driving force behind cultural transformation medicine toward peoplecenteredness thus ehealth literacy assisted innovative digital health solutions may support better experiences care objective purpose study explore relationship ehealth literacy patientreported experience measures prems among users outpatient care hungary methods early 2019 conducted crosssectional survey large representative online sample recruited hungarian general population ehealth literacy measured ehealth literacy scale eheals prems outpatient care measured set questions recommended organisation economic cooperation development oecd respondents attended outpatient visit within 12 months preceding survey bivariate relationships explored via polychoric correlation kruskalwallis test chisquare test capture nonlinear associations controlling covariates analyzed relationship eheals quartiles prems using multivariate probit ordinary least squares ordered logit logistic regression models results 1000 survey respondents 666 individuals 364 females 547 included study mean age 489 sd 176 years mean eheals score 293 sd 49 respondents higher eheals scores likely understand health care professionals hcps explanations 29242 p002 involved decision making care treatment 29182 p03 multivariate regression respondents lowest first quartile moderately high third quartile eheals scores differed significantly latter likely overall positive experience p02 experience fewer problems p02 addition respondents better experiences terms easy understand hcps explanations plt001 able ask questions last consultation p04 patientreported experiences individuals highest fourth quartile lowest first quartile eheals levels differ significantly items prem instrument neither composite prem scores generated prem items pgt05 models conclusions demonstrated association ehealth literacy prems potential patient physician systemrelated factors explaining negative experiences among people highest levels ehealth literacy warrant investigation may contribute development efficient ehealth literacy interventions research needed establish causal relationship ehealth literacy patientreported experiences
https://doi.org/10.1371/journal.pone.0202734
Shuba Kumar|Lakshmanan Jeyaseelan|Saradha Suresh|Ramesh C. Ahuja
Domestic violence and its mental health correlates in Indian women
2,005
Christian Medical College & Hospital|Institute of Child Health
background domestic spousal violence women farreaching mental health implications aims determine association domestic spousal violence poor mental health method household survey rural urban nonslum urban slum areas seven sites india population women aged 1549 years sampled using probability proportionate size self report questionnaire used assess mental health status structured questionnaire elicited spousal experiences violence results 9938 women surveyed 40 reported poor mental health logistic regression showed women reporting violence slap hit kick beat 22 95 ci 2025 violence four types physically violent behaviour 35 95 ci 294351 increased risk poor mental health conclusions findings indicate strong association domestic spousal violence poor mental health underscore need appropriate interventions
https://doi.org/10.1371/journal.pone.0212657
Steven J. Ondersma|Dace S. Svikis|Charles R. Schuster
Computer-Based Brief Intervention
2,007
Wayne State University|Virginia Commonwealth University|Wayne State University
background drug use among parenting women significant risk factor range negative child outcomes including exposure violence child maltreatment child behavior problems implementation brief interventions population may greatly facilitated computerbased interventions design randomized clinical trial 4month followup settingparticipants participants 107 postpartum women recruited urban obstetric hospital primarily serving lowincome population women randomized assessment versus assessment plus brief intervention conditions 76 71 returned followup evaluation intervention 20minute singlesession computerbased motivational intervention based motivational interviewing methods combined two nontailored mailings voucherbased reinforcement attendance initial intaketreatment session main outcome measures illicit drug use measured qualitative urinalysis selfreport results frequency illicit drug use marijuana increased slightly control group declined among intervention group participants p005 betweengroup mannwhitney u d050 magnitude intervention effects changes marijuana use frequency similar reach statistical significance pointprevalence analysis followup show significant group differences drug use however trends range assumptions regarding participants lost followup favored intervention group effect sizes moderate range odds ratios 14 47 conclusions results tentatively support efficacy highreach replicable brief intervention research seek replicate findings develop computer platform validated brief interventions drug use among parenting women significant risk factor range negative child outcomes including exposure violence child maltreatment child behavior problems implementation brief interventions population may greatly facilitated computerbased interventions randomized clinical trial 4month followup participants 107 postpartum women recruited urban obstetric hospital primarily serving lowincome population women randomized assessment versus assessment plus brief intervention conditions 76 71 returned followup evaluation 20minute singlesession computerbased motivational intervention based motivational interviewing methods combined two nontailored mailings voucherbased reinforcement attendance initial intaketreatment session illicit drug use measured qualitative urinalysis selfreport frequency illicit drug use marijuana increased slightly control group declined among intervention group participants p005 betweengroup mannwhitney u d050 magnitude intervention effects changes marijuana use frequency similar reach statistical significance pointprevalence analysis followup show significant group differences drug use however trends range assumptions regarding participants lost followup favored intervention group effect sizes moderate range odds ratios 14 47 results tentatively support efficacy highreach replicable brief intervention research seek replicate findings develop computer platform validated brief interventions
https://doi.org/10.1371/journal.pone.0061759
Akira-Sebastian Poncette|Lina Mosch|Claudia Spies|Malte L Schmieding|Fridtjof Schiefenhövel|Henning Krampe|Felix Balzer
Improvements in Patient Monitoring in the Intensive Care Unit: Survey Study
2,020
Einstein Center Digital Future|Humboldt-Universität zu Berlin|Charité - Universitätsmedizin Berlin|Freie Universität Berlin|Humboldt-Universität zu Berlin|Charité - Universitätsmedizin Berlin|Freie Universität Berlin|Humboldt-Universität zu Berlin|Charité - Universitätsmedizin Berlin|Freie Universität Berlin|Einstein Center Digital Future|Humboldt-Universität zu Berlin|Charité - Universitätsmedizin Berlin|Freie Universität Berlin|Einstein Center Digital Future|Humboldt-Universität zu Berlin|Charité - Universitätsmedizin Berlin|Freie Universität Berlin|Humboldt-Universität zu Berlin|Charité - Universitätsmedizin Berlin|Freie Universität Berlin|Einstein Center Digital Future|Humboldt-Universität zu Berlin|Charité - Universitätsmedizin Berlin|Freie Universität Berlin
background due demographic change recently coronavirus disease covid19 importance modern intensive care units icu becoming apparent one key components icu continuous monitoring patients vital parameters however existing advances informatics signal processing engineering could alleviate burden icus yet applied could due lack user involvement research development objective study focused satisfaction icu staff current patient monitoring suggestions future improvements aimed identify aspects monitoring interrupt patient care display devices remote monitoring use cases artificial intelligence ai whether icu staff members willing improve digital literacy contribute improvement patient monitoring aimed identify differences responses different professional groups methods survey study performed icu staff 4 icus german university hospital november 2019 january 2020 developed webbased 36item survey questionnaire analyzing preceding qualitative interview study icu staff clinical requirements future patient monitoring statistical analyses questionnaire results included median values bootstrapped 95 confidence intervals chisquare tests compare distributions item responses professional groups results total 86 270 icu physicians nurses completed survey questionnaire majority stated felt confident using patient monitoring equipment high rates falsepositive alarms many sensor cables interrupted patient care regarding future improvements respondents asked wireless sensors reduction number falsepositive alarms hospital standard operating procedures alarm management responses display devices proposed remote patient monitoring divided respondents indicated would useful earlier alerting responsible multiple wards ai icus would useful early detection complications increased risk mortality addition ai could propose guidelines therapy diagnostics transparency interoperability usability staff training essential promote use ai majority wanted learn new technologies icu required time learning physicians fewer reservations nurses aibased intelligent alarm management using mobile phones remote monitoring conclusions survey study icu staff revealed key improvements patient monitoring intensive care medicine hospital providers medical device manufacturers focus reducing false alarms implementing hospital alarm standard operating procedures introducing wireless sensors preparing use ai enhancing digital literacy icu staff results may contribute usercentered transfer digital technologies practice alleviate challenges intensive care medicine trial registration clinicaltrialsgov nct03514173 httpsclinicaltrialsgovct2shownct03514173
https://doi.org/10.2196/25333
Lawrence C. An|Elizabeth Bacon|Sarah T. Hawley|Penny Yang|Daniel M. Russell|Scott B. Huffman|Ken Resnicow
Relationship Between Coronavirus-Related eHealth Literacy and COVID-19 Knowledge, Attitudes, and Practices among US Adults: Web-Based Survey Study
2,021
University of Michigan–Ann Arbor|University of Michigan–Ann Arbor|VA Center for Clinical Management Research|VA Ann Arbor Healthcare System|University of Michigan–Ann Arbor|University of Michigan–Ann Arbor|Google (United States)|Google (United States)|University of Michigan–Ann Arbor
background global pandemic critical public able rapidly acquire new accurate health information internet major source health information ehealth literacy ability individuals find assess use health information available internet objective goals study assess coronavirusrelated ehealth literacy examine relationship ehealth literacy covid19related knowledge attitudes practices kaps methods conducted webbased survey representative sample 1074 us adults adapted 8item ehealth literacy scale develop coronavirusrelated ehealth literacy scale coveheals measure covid19related knowledge conspiracy beliefs adherence protective behaviors eg wearing facial masks social distancing analyses identified sociodemographic associations participants coveheals scores association coveheals measure covid19 kaps results internal consistency adapted coveheals measure high cronbach 92 mean score coveheals 290 sd 61 total 29 3061074 survey participants classified low coronavirusrelated ehealth literacy coveheals score lt26 independent associations found coveheals scores ethnicity standardized 083 p016 black participants education level standardized 151 p001 participants highschool education lower controlling demographic characteristics coveheals scores demonstrated positive independent associations knowledge standardized 168 plt001 adherence protective behaviors standardized 241 plt001 negative association conspiracy beliefs standardized 082 p009 conclusions study provides estimate coronavirusrelated ehealth literacy among us adults findings suggest substantial proportion us adults low coronavirusrelated ehealth literacy thus greater risk lower lessprotective covid19 kaps findings highlight need assess address ehealth literacy part covid19 control efforts potential strategies include improving quality health information covid19 available internet assisting simplifying webbased search information covid19 training improve general coronavirusspecific search skills
https://doi.org/10.1161/circulationaha.110.979740
Chun Lam|Ho Kee Koon|Vincent Chi?Ho Chung|Yin Ting Cheung
A public survey of traditional, complementary and integrative medicine use during the COVID-19 outbreak in Hong Kong
2,021
Chinese University of Hong Kong|Chinese University of Hong Kong|Chinese University of Hong Kong|Hong Kong Jockey Club|Chinese University of Hong Kong
background covid19 public actively sought nonpharmacological selfmanagement approaches prevent infection little known use traditional complementary integrative medicine tcim public preventive measures study investigated prevalence patterns tcim use pandemic identified factors associated use among general population hong kong methods online crosssectional survey conducted november december 2020 survey solicited information respondents sociodemographic characteristics risk perception pandemic use tcim pandemic logistic regression analysis conducted determine predictors tcim use results total 632 responses completion rate 881 analyzed tcim used 440 respondents pandemic popular forms tcim vitamins dietary supplements n 160 253 chinese herbal medicine n 122 193 pandemic frequently reported indication strengthening immune system especially vitamins dietary supplements n 142160 888 respondents reported using tcim likely female adjusted odds ratio aor 182 95 confidence interval ci 129259 higher education attainment aor 221 95 ci 139359 olderaged age gt55 years aor 177 95 ci 104302 respondents resided districts moderate high number confirmed covid19 cases aor 160 95 ci 107242 higher level risk perception aor 104 95 ci 101107 also likely use tcim conclusion tcim used commonly hong kong covid19 pandemic vaccination social distancing remain mainstay controlling pandemic professional bodies proactively consider public preferences provide information regarding effectiveness safety tcim covid19 prevention treatment
https://doi.org/10.1161/circoutcomes.118.005244
Anat Gesser?Edelsburg|Alon Diamant|Rana Hijazi|Gustavo S. Mesch
Correcting misinformation by health organizations during measles outbreaks: A controlled experiment
2,018
University of Haifa|University of Haifa|University of Haifa|University of Haifa
background epidemic crises information public receives social media misinformation health organizations required respond correct information gain publics trust influence follow recommended instructions objectives 1 examine ways health organizations correct misinformation concerning measles vaccination social networks two groups provaccination hesitant 2 examine types reactions two subgroups provaccination hesitant misinformation correction 3 examine effect misinformation correction two subgroups regarding reliability satisfaction selfefficacy intentions methods controlled experiment participants divided randomly two conditions experiment conditions dilemma presented sending child kindergarten followed identical facebook post voicing children mothers concerns third stage correction health organization presented differently two conditions condition 1 common information correction condition 2 recommended theorybased information correction mainly communicating information transparently addressing publics concerns study included n 243 graduate students faculty social welfare health sciences haifa university results statistically significant difference found reliability level attributed information correction health ministry control condition experimental condition sig0001 average reliability level subjects condition 2 568 considerably higher average reliability level subjects condition 1 464 significant difference found condition 1 condition 2 sig0001 average satisfaction health ministrys response condition 2 subjects 575 significantly higher average satisfaction level condition 1 subjects 466 similarly tested pro hesitant groups separately found preferred response presented condition 2 conclusion important organizations correct misinformation transparently address emotional aspects provaccination hesitant groups provaccination group captive audience requires full response addresses publics fears concerns
https://doi.org/10.1002/cncr.30535
Shaojie Li|Guanghui Cui|Atipatsa Chiwanda Kaminga|Sixiang Cheng|Huilan Xu
Associations Between Health Literacy, eHealth Literacy, and COVID-19–Related Health Behaviors Among Chinese College Students: Cross-sectional Online Study
2,021
Central South University|Shandong University of Traditional Chinese Medicine|Central South University|Mzuzu University|Central South University|Central South University
background covid19 pandemic internet significantly spread information providing people knowledge advice health protection regarding covid19 previous study demonstrated health ehealth literacy related covid19 prevention behaviors studies focused relationship health literacy ehealth literacy covid19related health behaviors latter includes preventative behaviors also conventional health behaviors objective objective study develop verify covid19related health behavior questionnaire explore status structure examine associations behaviors participants health literacy ehealth literacy methods snowball sampling method adopted recruit participants complete anonymous crosssectional questionnaire surveys online assessed sociodemographic information selfreported coronavirus knowledge health literacy ehealth literacy covid19related health behaviors results 1873 college students recruited 781 417 adequate health literacy mean ehealth literacy score 3016 sd 631 covid19related health behavior questionnaire presented twofactor structurecovid19specific precautionary behaviors conventional health behaviorswith satisfactory fit indices internal consistency cronbach 79 mean score covid19related health behaviors 5377 sd 803 scores differed significantly plt05 respect residence college year academic major family economic level selfreported health status family member friend infected coronavirus health literacy level linear regression analysis showed health literacy ehealth literacy positively associated covid19specific precautionary behaviors health literacy149 ehealth literacy368 plt001 conventional health behaviors health literacy219 ehealth literacy277 plt001 conclusions covid19related health behavior questionnaire valid reliable measure assessing health behaviors pandemic college students higher health literacy ehealth literacy actively adopt covid19related health behaviors additionally compared health literacy ehealth literacy closely related covid19related health behaviors public intervention measures based health ehealth literacy required promote covid19related health behaviors pandemic may helpful reduce risk covid19 infection among college students
https://doi.org/10.2196/24466
Shaojie Qi|Fengrui Hua|Shengyuan Xu|Zheng Zhou|Feng Liu
Trends of global health literacy research (1995–2020): Analysis of mapping knowledge domains based on citation data mining
2,021
Southwestern University of Finance and Economics|Southwestern University of Finance and Economics|Tohoku University|Southwestern University of Finance and Economics|Huaiyin Normal University
background uncertainties associated covid19 pandemic effectively improving peoples health literacy important ever drawing knowledge maps health literacy research data mining visualized measurement technology helps systematically present research status development trends global academic circles methods paper uses citespace carry metric analysis 9492 health literacy papers included web science mapping knowledge domains first based production theory scientific knowledge data mining citations main bodies country institution author produce health literacy knowledge well mutual cooperation collaboration network clarified additionally based quantitative framework cocitation analysis paper introduces interdisciplinary features development trends hot topics field finally using burst detection technology literature reveals research frontiers health literacy results results bc measures global health literacy research collaboration network show united states australia united kingdom major forces current international collaboration network health literacy still relatively transnational collaborations eastern western research institutions collaborations public environmental occupational health health care science services nursing health policy services active past five years research topics health literacy research evolve time mental health active research field recent years conclusions systematic approach needed address challenges health literacy network framework cooperation health literacy regional national global levels strengthened promote application health literacy research future anticipate research field expand two directions namely mental health literacy ehealth literacy closely linked social development issues results study provide references future applied research health literacy
https://doi.org/10.1136/bmjopen-2020-038416
Hugo Cogo?Moreira|Régis B Andriolo|Latife Yázigi|George B. Ploubidis|Clara Regina Brandão de Ávila|Jair J. Mari
Music education for improving reading skills in children and adolescents with dyslexia
2,012
Universidade Federal de São Paulo|Universidade do Estado do Pará|Universidade Federal de São Paulo|University of London|London School of Hygiene & Tropical Medicine|Universidade Federal de São Paulo|Universidade Federal de São Paulo
background dyslexia developmental dyslexia specific reading disability specific learning disorder neurobiological origin marked difficulties accurate fluent recognition words poor spelling people average average intelligence difficulties cannot attributed another cause example poor vision hearing difficulty lack socioenvironmental opportunities motivation adequate instruction studies correlated reading skills musical abilities hypothesized musical training may able remediate timing difficulties improve pitch perception increase spatial awareness thereby positive effect skills needed development language literacy objectives study effectiveness music education reading skills oral reading skills reading comprehension reading fluency phonological awareness spelling children adolescents dyslexia search methods searched following electronic databases june 2012 central 2012 issue 5 medline 1948 may week 4 2012 embase 1980 2012 week 22 cinahl searched 7 june 2012 lilacs searched 7 june 2012 psycinfo 1887 may week 5 2012 eric searched 7 june 2012 arts humanities citation index 1970 6 june 2012 conference proceedings citation index social sciences humanities 1990 6 june 2012 worldcat searched 7 june 2012 also searched international clinical trials registry platform ictrp reference lists studies apply date language limits selection criteria planned include randomized controlled trials looked studies included least one primary outcomes primary outcomes related main domain reading oral reading skills reading comprehension reading fluency phonological awareness spelling measured validated instruments secondary outcomes self esteem academic achievement data collection analysis two authors hcm rba independently screened titles abstracts identified search strategy determine eligibility analysis planned use mean difference continuous data 95 confidence intervals use randomeffects statistical model effect estimates two studies could combined metaanalysis main results retrieved 851 references via search strategy randomized controlled trials testing music education improvement reading skills children dyslexia could included review authors conclusions evidence available randomized controlled trials base judgment effectiveness music education improvement reading skills children adolescents dyslexia uncertainty warrants research via randomized controlled trials involving interdisciplinary team musicians hearing speech therapists psychologists physicians
https://doi.org/10.1016/j.cardfail.2011.06.651
Rafael de la Torre|Susana Solá|Gimena Hernández|Mag?? Farré|Jesús Pujol|Joaquín Rodríguez|Josep M. Espadaler|Klaus Langohr|Aida Cuenca?Royo|Alessandro Príncipe|Laura Xicota|Nathalie Janel|Silvina Catuara?Solarz|Gonzalo Sánchez?Benavides|Henri Bléhaut|Iván Dueñas-Espín|Laura del Hoyo|Bessy Benejam|Laura Blanco?Hinojo|Sebastià Videla|Montserrat Fitó|Jean Maurice Delabar|Mara Dierssen
Safety and efficacy of cognitive training plus epigallocatechin-3-gallate in young adults with Down's syndrome (TESDAD): a double-blind, randomised, placebo-controlled, phase 2 trial
2,016
Pompeu Fabra University|Hospital del Mar Research Institute|Municipal Institute for Medical Research|Pompeu Fabra University|Hospital del Mar Research Institute|Municipal Institute for Medical Research|Pompeu Fabra University|Hospital del Mar Research Institute|Municipal Institute for Medical Research|Universitat Autònoma de Barcelona|Pompeu Fabra University|Hospital del Mar Research Institute|Municipal Institute for Medical Research|Hospital Del Mar|Hospital del Mar Research Institute|Centro de Investigación Biomédica en Red de Salud Mental|Pompeu Fabra University|Hospital del Mar Research Institute|Municipal Institute for Medical Research|Hospital Del Mar|Hospital del Mar Research Institute|Municipal Institute for Medical Research|Universitat Politècnica de Catalunya|Pompeu Fabra University|Hospital del Mar Research Institute|Municipal Institute for Medical Research|Hospital Del Mar|Hospital del Mar Research Institute|Centro de Investigación Biomédica en Red de Salud Mental|Pompeu Fabra University|Hospital del Mar Research Institute|Municipal Institute for Medical Research|Sorbonne Paris Cité|Université Paris Cité|French National Centre for Scientific Research|Pompeu Fabra University|Centre for Biomedical Network Research on Rare Diseases|Pompeu Fabra University|Hospital del Mar Research Institute|Municipal Institute for Medical Research|Fondation Jérôme-Lejeune|Pompeu Fabra University|Hospital del Mar Research Institute|Municipal Institute for Medical Research|Pompeu Fabra University|Hospital del Mar Research Institute|Municipal Institute for Medical Research|Unió Catalana de Centres de Desenvolupament Infantil i Atenció Precoç|Hospital Del Mar|Hospital del Mar Research Institute|Centro de Investigación Biomédica en Red de Salud Mental|Unió Catalana de Centres de Desenvolupament Infantil i Atenció Precoç|Pompeu Fabra University|Pompeu Fabra University|Hospital del Mar Research Institute|Municipal Institute for Medical Research|Sorbonne Paris Cité|Université Paris Cité|French National Centre for Scientific Research|Institut du Cerveau|Inserm|Sorbonne Université|Pompeu Fabra University|Centre for Biomedical Network Research on Rare Diseases
background early cognitive intervention routine therapeutic approach used amelioration intellectual deficits individuals downs syndrome effects limited hypothesised administration green tea extract containing epigallocatechin3gallate egcg would improve effects nonpharmacological cognitive rehabilitation young adults downs syndrome methods enrolled adults aged 1634 years downs syndrome outpatient settings catalonia spain downs syndrome genetic variations trisomy 21 partial trisomy mosaic translocation doubleblind placebocontrolled phase 2 single centre trial tesdad participants randomly assigned imimhospital del mar medical research institute receive egcg 9 mgkg per day placebo cognitive training 12 months followed participants 6 months treatment discontinuation randomly assigned participants using randomnumber tables balanced allocation sex intellectual quotient participants families researchers assessing participants masked treatment allocation primary endpoint cognitive improvement assessed neuropsychologists battery cognitive tests episodic memory executive function functional measurements analysis intentiontotreat basis trial registered clinicaltrialsgov number nct01699711 findings study done june 5 2012 june 6 2014 84 87 participants downs syndrome included intentiontotreat analysis 12 months 43 egcg cognitive training group 41 placebo cognitive training group differences groups significant 13 15 tests tesdad battery eight nine adaptive skills adaptive behavior assessment system ii abasii 12 months participants treated egcg cognitive training significantly higher scores visual recognition memory pattern recognition memory test immediate recall adjusted mean difference 623 percentage points 95 ci 031 1214 p0039 04 005 084 inhibitory control cats dogs total score adjusted mean difference 048 002 093 p0041 028 019 074 cats dogs total response time adjusted mean difference 458 854 062 p0024 027 072 020 adaptive behaviour abasii functional academics score adjusted mean difference 549 213 886 p0002 039 006 084 differences noted adverse effects two treatment groups interpretation egcg cognitive training 12 months significantly effective placebo cognitive training improving visual recognition memory inhibitory control adaptive behaviour phase 3 trials larger population individuals downs syndrome needed assess confirm longterm efficacy egcg cognitive training funding jrme lejeune foundation instituto de salud carlos iii feder mineco generalitat de catalunya
https://doi.org/10.2196/50211
Ibrahim Sendagire|Maarten Schim van der Loeff|Mesach Mubiru|Joseph Konde-Lule|Frank Cobelens
Long Delays and Missed Opportunities in Diagnosing Smear-Positive Pulmonary Tuberculosis in Kampala, Uganda: A Cross-Sectional Study
2,010
Kampala Capital City Authority|Academic Medical Center|Public Health Service of Amsterdam|Kampala Capital City Authority|Makerere University|Amsterdam Institute for Global Health and Development|Academic Medical Center
background early detection treatment tuberculosis cases hallmark successful tuberculosis control conducted crosssectional study public primary health facilities kampala city uganda quantify diagnostic delay among pulmonary tuberculosis ptb patients assess associated factors describe trajectories patients health care seeking methodologyprincipal findings semistructured interviews new smearpositive ptb patients 15 years registered treatment april 2007 april 2008 253 patients studied median total delay 8 weeks iqr 412 median patient delay 4 weeks interquartile range iqr 18 median health service delay 4 weeks iqr 28 long total delay 14 weeks observed 61253 241 patients long health service delay 6 weeks 71242 293 long patient delay 8 weeks 47242 194 patients knew tb curable less likely long total delay adjusted odds ratio aor 028 95ci 011073 long patient delay aor 036 95ci 013097 female aor 198 95ci 106371 staying 5 years current residence aor 224 95ci 118427 tested hiv aor 372 95ci 142975 associated long health service delay health service delay contributed 50 total delay ninetyone percent 231 patients visited one health care providers diagnosed average median 4 visits range 130 four patients systemic symptoms time diagnosis tb made conclusionssignificance diagnostic delay among tuberculosis patients kampala common long reflects patients waiting long seeking care health services waiting systemic symptoms present examining sputum smears results missed opportunities diagnosis
https://doi.org/10.1016/j.cardfail.2013.02.002
Musa Ahmed Zayyad|Mehmet Toycan
Factors affecting sustainable adoption of e-health technology in developing countries: an exploratory survey of Nigerian hospitals from the perspective of healthcare professionals
2,018
Cyprus International University|Cyprus International University
background ehealth technology applications essential tools modern information technology improve quality healthcare delivery hospitals developed developing countries however despite positive benefits studies indicate rate ehealth adoption developing countries either low underutilized due part barriers resistance healthcare professionals poor infrastructure low technical expertise among others objective aim study investigate identify analyze underlying factors affect healthcare professionals decision adopt use ehealth technology applications developing countries particular reference hospitals nigeria methods study used cross sectional approach form closeended questionnaire collect quantitative data sample 465 healthcare professionals randomly selected 15 hospitals nigeria used modified technology acceptance model tam dependent variable external factors independent variables collected data analyzed using spss statistical analysis frequency test reliability analysis correlation coefficient analysis results results obtained correspond findings researches published indicate perceived usefulness belief willingness well attitude healthcare professionals significant influence intention adopt use ehealth technology applications strategic factors identified include low literacy level experience using ehealth technology applications lack motivation poor organizational management policies conclusion study contributes literature pinpointing significant areas findings positively affect found useful healthcare policy decision makers nigeria developing countries help understand areas priorities weaknesses planning ehealth technology adoption implementation
https://doi.org/10.1371/journal.pmed.1003369
Christina Cheng|Alison Beauchamp|Gerald R. Elsworth|Richard H. Osborne
Applying the Electronic Health Literacy Lens: Systematic Review of Electronic Health Interventions Targeted at Socially Disadvantaged Groups
2,020
Swinburne University of Technology|Deakin University|Monash University|Australian Institute for Musculoskeletal Science|Sunshine Hospital|Western Health|University of Melbourne|Swinburne University of Technology|Swinburne University of Technology
background electronic health ehealth potential improve health outcomes however ehealth systems need match ehealth literacy needs users equitably adopted socially disadvantaged groups lower access skills use technologies risk digitally marginalized leading potential widening health disparities objective systematic review aims explore role ehealth literacy user involvement developing ehealth interventions targeted socially disadvantaged groups methods systematic search conducted across 10 databases ehealth interventions targeted older adults ethnic minority groups lowincome groups lowliteracy groups rural communities ehealth literacy framework used examine ehealth literacy components reviewed interventions results analyzed using narrative synthesis results total 51 studies reporting results 48 interventions evaluated studies targeted older adults ethnic minorities 2 studies focusing lowliteracy groups ehealth literacy considered development studies ehealth literacy assessment conducted user involvement designing interventions limited ehealth intervention developmental frameworks rarely used strategies assist users engaging technical systems seldom included interventions accessibility features limited results included studies also provided inconclusive evidence effectiveness ehealth interventions conclusions findings highlight ehealth literacy generally overlooked developing ehealth interventions targeted socially disadvantaged groups whereas evidence effectiveness interventions limited ensure equal access inclusiveness age ehealth ehealth literacy disadvantaged groups needs addressed help avoid digital divide assist realization recent technological advancements importantly improve health equity
https://doi.org/10.2196/17208
Ramzi Amri|Liliana Bordeianou|Patricia Sylla|David L. Berger
Colon cancer surgery following emergency presentation: effects on admission and stage-adjusted outcomes
2,015
Massachusetts General Hospital|Harvard University|Massachusetts General Hospital|Harvard University|Massachusetts General Hospital|Harvard University|Massachusetts General Hospital|Harvard University
background emergency presentation colon cancer intuitively related advanced disease measured effect outcomes surgically treated colon cancer methods retrospective cohort 1071 surgical colon cancer patients 2004 2011 102 emergency cases requiring surgery within index admission analyzed results emergency patients required longer surgeries median 141 vs 124 minutes p 04 longer median admissions 8 vs 5 p 001 readmissions 127 vs 71 p 040 perioperative mortality 78 vs 8 p 001 surgical pathology displayed higher rates nodepositive disease 566 vs 386 p 001 extramural vascular invasion 396 vs 291 p 021 metastatic disease 196 vs 8 p 001 consequently adjusting staging emergency presentations considerably higher mortality odds ratio 207 p 003 shorter diseasefree survival hazard ratio 139 p 042 conclusions emergency presentation stageindependent poor prognostic factor associated aggressive tumor biology resulting longer surgeries admissions frequent readmissions worsening outcomes increasing healthcare costs
https://doi.org/10.1177/2047487318766954
Lian Leng Low|Shaohua Tan|Matthew Joo Ming Ng|Wei Yi Tay|Li Choo Ng|Kanchana D Balasubramaniam|Rachel Marie Towle|Kheng Hock Lee
Applying the Integrated Practice Unit Concept to a Modified Virtual Ward Model of Care for Patients at Highest Risk of Readmission: A Randomized Controlled Trial
2,017
Duke-NUS Medical School|Singapore General Hospital|Duke-NUS Medical School|Singapore General Hospital|Duke-NUS Medical School|Singapore General Hospital|Duke-NUS Medical School|Singapore General Hospital|Duke-NUS Medical School|Singapore General Hospital|Singapore General Hospital|Singapore General Hospital|Duke-NUS Medical School|Singapore General Hospital
background emerging evidence virtual ward care model showed multidisciplinary case management inadequate reduce readmissions death high risk patients consensus interventions encompass prehospital discharge postdischarge transitional care effective integrated practice units ipu proposed approach restructuring organization work processes multidisciplinary teams achieve value healthcare primary objective evaluate novel application ipu concept organize modified virtual ward model incorporating prehospital discharge transitional care reduce readmissions patients highest risk readmission methods conducted open label assessor blinded randomized controlled trial patients one unscheduled readmissions prior 90 days lace score 10 840 patients randomized 11 ratio blocks 6 intervention program n 420 control n 420 allocation concealment effected via offsite telephone service maintained hospital administrator intervention patients received discharge planning medication reconciliation coaching selfmanagement chronic diseases using standardized action plans individualized care plan complete written discharge instructions appointments schedule medication changes contact information outpatient vw nurse discharge discharge care handed outpatient vw team patients closely monitored vw three months included telephone review within 72 hours discharge home assessment regular telephone reviews identify early complications early review clinics patients destabilize vw meet daily discuss new patients review care plans patients control patients received standard hospital care included standardized patient copy hospital discharge summary listing medical diagnoses medications follow arranged primary care provider specialist considered necessary primary outcome unplanned readmission rate hospital within 30 days discharge secondary outcomes included unplanned readmission rate emergency department ed attendance rate hospital probability without readmission death 180 days discharge length stay mortality rate 90day compared two groups outcome data objectively retrieved hospital national electronic health records blinded outcome assessor findings patients outcomes included intentiontotreat analysis characteristics study groups similar patients intervention group significant reduction number 30day readmissions irr 067 95 ci 052 086 p 0001 number 30day emergency department attendances irr 060 95 ci 046 079 p0001 compared receiving standard hospital care effectiveness sustained 90 180 days intervention group utilized 1164 fewer hospital bed days 90day post discharge adverse events reported conclusion applying integrated practice unit concept virtual ward program resulted reduced readmissions patients highest risk readmission
https://doi.org/10.1371/journal.pone.0049542
Saurav Ghimire|Ronald L. Castelino|Nicole Lioufas|Gregory M. Peterson|Syed Tabish R. Zaidi
Nonadherence to Medication Therapy in Haemodialysis Patients: A Systematic Review
2,015
University of Tasmania|University of Tasmania|Royal Hobart Hospital|University of Tasmania|University of Tasmania
background endstage kidney disease eskd patients often prescribed multiple medications together demanding weekly schedule dialysis sessions increased number medicines associated regimen complexity predispose high risk medication nonadherence review summarizes existing literature nonadherence identifies factors associated nonadherence medication therapy patients undergoing haemodialysis methods comprehensive search pubmed embase cinahl psycinfo cochrane database systematic reviews covering period 1970 november 2014 performed following predefined inclusion exclusion criteria reference lists relevant materials reviewed data study characteristics measures nonadherence prevalence rates factors associated nonadherence collected preferred reporting items systematic reviews metaanalyses prisma guidelines followed conducting systematic review results 920 relevant publications 44 included prevalence medication nonadherence varied 125 986 widespread heterogeneity measures definitions employed common patientrelated factors significantly associated nonadherence younger age noncaucasian ethnicity illness interfering family life smoker living single divorced widowed similarly diseaserelated factors include longevity haemodialysis recurrent hospitalization depressive symptoms concomitant illness like diabetes hypertension medicationrelated factors daily tablet count total pill burden number phosphate binders prescribed complexity medication regimen also associated poor adherence conclusions number patient disease medicationrelated factors associated medication nonadherence haemodialysis patients clinicians aware factors adherence medications optimised haemodialysis patients future research directed towards welldesigned prospective longitudinal studies developing standard definitions validating available measurement tools focusing role additional factors psychosocial behavioural factors predicting nonadherence medications
https://doi.org/10.1371/journal.pmed.1002442
Steve M. Taylor|Jane P. Messina|Carla Cerami Hand|Jonathan J. Juliano|Jérémie Muwonga|Antoinette Tshefu|Benjamin Atua|Michael Emch|Steven R. Meshnick
Molecular Malaria Epidemiology: Mapping and Burden Estimates for the Democratic Republic of the Congo, 2007
2,011
Duke Medical Center|University of North Carolina at Chapel Hill|University of North Carolina at Chapel Hill|University of North Carolina at Chapel Hill|University of North Carolina at Chapel Hill|Programme National Multisectoriel de Lutte contre le sida|University of Kinshasa|Programme National Multisectoriel de Lutte contre le sida|University of North Carolina at Chapel Hill|University of North Carolina at Chapel Hill
background epidemiologic data malaria scant many highburden countries including democratic republic congo drc suffers secondhighest global burden malaria malaria control efforts regions challenging infrastructure require reproducible efficient surveillance employed new highthroughput molecular testing characterize state malaria control drc estimate childhood mortality attributable excess malaria transmission methods findings demographic health survey crosssectional populationbased cluster household survey adults aged 1559 years 2007 employing structured questionnaires dried blood spot collection parasitemia detected realtime pcr survey responses measured adoption malaria control measures under5 health indices response rate 99 household level 8886 households surveyed 300 clusters 8838 respondents molecular results available overall prevalence parasitemia 335 95 confidence interval ci 32349 p falciparum prevalent species either monoinfection 904 95 ci 888921 combined p malariae 49 95 ci 3759 p ovale 06 95 ci 0109 77 95 ci 6886 households children 5 owned insecticidetreated bednet itn 68 95 ci 6175 underfives slept itn preceding night overall under5 mortality rate 147 deaths per 1000 live births 95 ci 141153 clusters associated increased p falciparum prevalence based population attributable fraction 26488 yearly under5 deaths attributable excess malaria transmission conclusions adult p falciparum prevalence substantial drc associated under5 mortality molecular testing offers new generalizable efficient approach characterizing malaria endemicity underserved countries
https://doi.org/10.2196/13637
Mark J. D. Jordans|Nagendra P. Luitel|Emily Garman|Brandon A. Kohrt|Sujit D Rathod|Pragya Shrestha|Ivan H. Komproe|Crick Lund|Vikram Patel
Effectiveness of psychological treatments for depression and alcohol use disorder delivered by community-based counsellors: two pragmatic randomised controlled trials within primary healthcare in Nepal
2,019
King's College London|University of Cape Town|George Washington University|London School of Hygiene & Tropical Medicine|Utrecht University|HealthNet TPO|University of Cape Town|King's College London|Harvard Global Health Institute|Harvard University
background evidence shows benefits psychological treatments lowresource countries yet government health systems include psychological services aim evaluating clinical value adding psychological treatments delivered communitybased counsellors primary carebased mental health services depression alcohol use disorder aud recommended mental health gap action programme mhgap method two randomised controlled trials separately depression aud carried participants randomly allocated 11 mental healthcare delivered mhgaptrained primary care workers psychoeducation psychotropic medicines indicated services plus individual psychological treatments healthy activity program depression counselling alcohol problems primary outcomes symptom severity measured using patient health questionnaire 9 item phq9 depression alcohol use disorder identification test aud functional impairment measured using world health organization disability assessment schedule whodas 12 months postenrolment results participants depression intervention arm n 60 greater reduction phq9 whodas scores compared participants control n 60 phq9 590 95 ci 755 425 368 95 ci 568 167 p lt 0001 cohens 066 whodas 1221 95 ci 1958 484 1074 95 ci 1996 153 p 0022 cohens 042 aud trial significant effect found comparing control n 80 intervention participants n 82 conclusion adding psychological treatment delivered communitybased counsellors increases treatment effects depression compared mhgapbased services primary health workers 12 months posttreatment declaration interest none
https://doi.org/10.3126/kumj.v9i1.6255
Nikoletta Zeschick|Luca Frank|Kathrin Schnitzius|Birgit Stubner|Thomas Kühlein|Marco Roos|Piet van der Keylen
Auswirkungen eines Wahlfachs zur evidenzbasierten klinischen Entscheidungsfindung auf die Kompetenzen und Einstellungen von Medizinstudierenden: Eine Pilotstudie
2,021
Friedrich-Alexander-Universität Erlangen-Nürnberg|Friedrich-Alexander-Universität Erlangen-Nürnberg|Friedrich-Alexander-Universität Erlangen-Nürnberg|Friedrich-Alexander-Universität Erlangen-Nürnberg|Friedrich-Alexander-Universität Erlangen-Nürnberg|Friedrich-Alexander-Universität Erlangen-Nürnberg|Friedrich-Alexander-Universität Erlangen-Nürnberg
background evidencebased medicine ebm teaching subject increasingly taken account master plan 2020 date neither theoretical requirements practical applications ebm consistently implemented clinical curriculum fill gap digital tutorbased ebm course developed aim identify student characteristics statistical competence need cognition nfc work experience patterns avem diagnostic uncertainty first cohort order ensure successful course implementation prepare future doctors role mediators health literacy using ebm methods methods longterm study started summer term 2019 10 medical students clinical training measurements conducted t0 course attendance t1 sociodemographic variables taken t0 quick risk test pru questionnaire nfc scale avem collected t0 t1 results half students started doctoral thesis attending course first test results quick risk test t0 50 90 t1 60 100 students showed high scores nfc scale x 46 sd 052 x t0 t1 01 medium scores perfectionism scale x 38 sd 051 x t0 t1 01 resignation tendency x 38 sd 117 x t0 t1 01 scale aggressive problem solving x 39 sd 106 x t0 t1 02 achieved high levels anxiety due diagnostic uncertainty x 48 sd 069 x t0 t1 04 scale concern poor outcomes x 39 sd 154 x t0 t1 06 scale restraint disclosing uncertainty patients pronounced scale restraint disclosing errors physicians x 35 sd 093 x t0 t1 03 compared x 23 sd 120 x t0 t1 01 discussion statistical competence improved course attendance one student able correctly answer items t1 nfc avem strongly expressed sensitive change sample greatest changes observed scales concern poor results fear diagnostic uncertainty decreased course participation conclusion long term development new measuring instrument assess ebm competencies instead quick risk test conceivable longitudinal design also enable us make causal interpretations track changes students competence feelings behaviour attitudes
https://doi.org/10.1371/journal.pone.0007925
Auden C. McClure|Mike Stoolmiller|Susanne E. Tanski|Rutger C. M. E. Engels|James D. Sargent
Alcohol Marketing Receptivity, Marketing?Specific Cognitions, and Underage Binge Drinking
2,012
Dartmouth College|Oregon Department of Education|University of Oregon|Dartmouth College|Radboud University Nijmegen|Dartmouth College
background exposure alcohol marketing prevalent associated initiation progression alcohol use underage youth mechanism influence well understood however study tests model proposes alcoholspecific cognitions mediators relation alcohol marketing problematic drinking among experimental underage drinkers methods study describes crosssectional analysis 1734 us 15 20yearold underage drinkers recruited national study media substance use subjects queried number alcohol marketing variables including tv time internet time favorite alcohol ad ownership alcoholbranded merchandise abm exposure alcohol brands movies relation exposures current 30day binge drinking assessed proposed mediators relation including marketingspecific cognitions drinker identity favorite brand drink favorable alcohol expectancies alcohol norms paths tested structural equation model controlled sociodemographics personality peer drinking results almost onethird sample ever drinkers engaged 30day binge drinking correlations mediators statistically significant range 016 047 significantly associated binge drinking statistically significant mediation found association abm ownership binge drinking drinker identity favorite brand drink also mediated path movie brand exposure binge drinking peer drinking sensation seeking associated binge drinking paths mediators conclusions associations alcohol marketing binge drinking mediated marketingspecific cognitions assess drinker identity brand allegiance cognitions marketers aim cultivate consumer
https://doi.org/10.15171/ijhpm.2014.60
Sharon J. Herring|Deborah B. Nelson|Adam Davey|Alicia A. Klotz|La Vette Dibble|Emily Oken|Gary D. Foster
Determinants of Excessive Gestational Weight Gain in Urban, Low-Income Women
2,012
Temple University|Temple University|Temple University|Temple University|Temple University|Harvard Pilgrim Health Care|Harvard University|Temple University
background factors influencing excessive weight gain pregnancy wellstudied among urban lowincome women methods prospective cohort study 94 prenatal care patients large university hospital philadelphia examined associations modifiable midpregnancy behaviors nonmodifiable early pregnancy factors excessive gestational weight gain data collected questionnaires medical record abstraction 2009 2011 findings majority women african american 83 100 received medicaid nearly two thirds 60 overweight obese early pregnancy 41 experienced excessive gain multivariable logistic regression analyses significant predictors excessive gestational weight gain included high early pregnancy body mass index odds ratio 420 95 confidence interval ci 1431234 overweightobese vs normal weight nulliparity 335 95 ci 117962 nulliparity vs multiparity clinician advice discordant institute medicine guidelines 588 95 ci 1043332 discordant vs concordant advice watching 2 hours television daily 018 95 ci 003103 engaging regular physical activity pregnancy 035 95 ci 011109 suggestive reduced risk excessive gain conclusions sample urban lowincome women high early pregnancy body mass index nulliparity discordant clinician advice directly associated excessive gestational weight gain trend toward decreased risk viewing fewer hours television engaging regular physical activity intervening targets may optimize gestational weight gain promote longterm maternal health
https://doi.org/10.3389/fpubh.2019.00392
Anna Barker|Peter Cameron|Leon Flicker|Glenn Arendts|Caroline Brand|Christopher Etherton?Beer|Andrew Forbes|Terry Haines|Anne-Marie Hill|Peter Hunter|Judy Lowthian|Samuel R. Nyman|Julie Redfern|De Villiers Smit|Nicholas Waldron|Eileen M. Boyle|Ellen MacDonald|Darshini Ayton|Renata Morello|Keith Hill
Evaluation of RESPOND, a patient-centred program to prevent falls in older people presenting to the emergency department with a fall: A randomised controlled trial
2,019
Monash University|Alfred Health|Monash University|Royal Perth Hospital|Harry Perkins Institute of Medical Research|University of Western Australia|Harry Perkins Institute of Medical Research|University of Western Australia|Melbourne Health|Monash University|University of Melbourne|Royal Perth Hospital|Harry Perkins Institute of Medical Research|University of Western Australia|Monash University|Monash Health|Monash University|Curtin University|Alfred Health|Monash University|Bournemouth University|Westmead Institute|University of Sydney|Alfred Health|Government of Western Australia|Government of Western Australia Department of Health|Curtin University|Royal Perth Hospital|Monash University|Monash University|Curtin University
background falls leading reason older people presenting emergency department ed many experience falls little evidence exists guide secondary prevention population randomised controlled trial rct investigated whether 6month telephonebased patientcentred programrespondhad effect falls fall injuries older people presenting ed fall methods findings communitydwelling people aged 6090 years presenting ed fall planned discharge home within 72 hours recruited two eds australia participants enrolled could walk without handson assistance use telephone free cognitive impairment minimental state examination 23 recruitment occurred 1 april 2014 29 june 2015 participants randomised receive either respond intervention usual care control respond comprised 1 homebased risk assessment 2 6 months telephonebased education coaching goal setting support evidencebased risk factor management 3 linkages existing services primary outcomes falls fall injuries 12month followup secondary outcomes included ed presentations hospital admissions fractures death falls risk falls efficacy quality life assessors blind group allocation collected outcome data via postal calendars telephone followup hospital records 430 people primary outcome analysis217 randomised respond 213 control mean age participants 73 years 55 female falls per personyear 115 respond group 183 control incidence rate ratio irr 065 95 ci 043099 p 0042 significant difference fall injuries irr 081 051129 p 0374 rate fractures significantly lower respond group compared control 005 versus 012 irr 037 95 ci 015091 p 003 significant differences secondary outcomes groups ed presentations hospitalisations falls risk falls efficacy quality life two deaths respond group one control group adverse events unintended harm reported limitations study high number dropouts n 93 possible underreporting falls fall injuries hospitalisations across groups relatively small number fracture events conclusions study providing telephonebased patientcentred falls prevention program reduced falls fall injuries older people presenting ed fall among secondary outcomes fractures reduced adopting patientcentred strategies routine clinical practice falls prevention could offer opportunity improve outcomes reduce falls patients attending ed trial registration australian new zealand clinical trials registry actrn12614000336684
https://doi.org/10.1192/bjp.bp.112.112938
Stefan Fischerauer|Mojtaba Talaei?Khoei|Rens Bexkens|David Ring|Luke S. Oh|Ana?Maria Vranceanu
What Is the Relationship of Fear Avoidance to Physical Function and Pain Intensity in Injured Athletes?
2,018
null
background fear avoidance play prominent role maladaptive responses injury injured athletes painrelated fear fear avoidance behavior may substantial influence recovery process specifically may explain able reach preinjury abilities whereas others unable return sport questionspurposes 1 fear avoidance athletes associated decreased physical function injury 2 degree fear avoidance associated athletes pain intensity methods crosssectional study recruited injured athletesdefined patients sportsrelated injury weekly engagement sport activities participation competitive events part team club selfidentification athlete desire return sport recoveryfrom orthopaedic sports medicine center major urban university hospital 130 approached patients 102 84 men mean sd age 25 85 years met inclusion criteria participants completed demographic questionnaire athlete fear avoidance questionnaire assesses injuryrelated fear avoidance behavior specifically athletic population pain catastrophizing scale hospital anxiety depression scale two patientreported outcomes measurement information system measures physical function computerized adaptive testing cat pain intensity cat results controlling age injury region upper versus lower extremity catastrophic thinking emotional distress found increase athletes fear avoidance associated decrease physical function b 032 p 0002 model explained 30 variation physical function 73 explained uniquely fear avoidance controlling initial appointmentfollowup surgery current condition multiple pain conditions history prior sportrelated injurysurgery pain medication prescription catastrophic thinking emotional distress athletes fear avoidance associated pain b 014 p 0249 model explained 40 variation pain intensity pain catastrophizing b 030 p 0001 uniquely explained 71 variation conclusions injured athletes fear avoidance independently associated decreased physical function whereas pain catastrophizing associated high pain intensity level athletes fear avoidance catastrophic thinking pain accounted clinical interventions aimed helping athletes improve recovery return sport level evidence level ii prognostic study
https://doi.org/10.2196/37693
Xiaoman Zhao|Ju Fan|Iccha Basnyat|Baijing Hu
Online Health Information Seeking Using “#COVID-19 Patient Seeking Help” on Weibo in Wuhan, China: Descriptive Study
2,020
Renmin University of China|Renmin University of China|James Madison University|Renmin University of China
background first detected wuhan china december 2019 covid19 pandemic stretched medical system wuhan posed challenge states risk communication efforts timely access quality health care information outbreaks infectious diseases effective curtail spread disease feelings anxiety although existing studies extended knowledge online health informationseeking behavior processes motivations rarely findings applied outbreak moreover relatively little recent research people china using internet seeking health information pandemic objective aim study explore people china using internet seeking health information pandemic drawing previous research online health information seeking study asks following research questions covid19 patient seeking help hashtag used patients wuhan seeking health information weibo peak outbreak kinds health information patients wuhan seeking weibo peak outbreak methods using entity identification textual analysis 10908 posts weibo identified 1496 patients covid19 using covid19 patient seeking help explored online health informationseeking behavior results curve hashtag posting provided dynamic picture public attention covid19 pandemic many patients faced difficulties accessing offline health care services general findings confirmed internet used chinese public important source health information lockdown policy found cut patients social support network preventing seeking help family members ability seek information help online especially young children older adult members pandemic high proportion female users seeking health information help parents older adults home searched information included accessing medical treatment managing selfquarantine offline online support conclusions overall findings contribute understanding health informationseeking behaviors outbreak highlight importance paying attention information needs vulnerable groups role social media may play
https://doi.org/10.3389/fpubh.2022.793033
Abdul Bari|Salim Sadruddin|Arif Raza Khan|Ibad ul Haque Khan|Asia Khan|Iqbal A Lehri|W. Bentley Macleod|Matthew P. Fox|Donald M. Thea|Shamim Qazi
Community case management of severe pneumonia with oral amoxicillin in children aged 2–59 months in Haripur district, Pakistan: a cluster randomised trial
2,011
United States Educational Foundation in Pakistan|Save the Children|United States Educational Foundation in Pakistan|United States Educational Foundation in Pakistan|United States Educational Foundation in Pakistan|Boston University|Center for Global Health|Boston University|Center for Global Health|Boston University|Center for Global Health|World Health Organization
background first dose oral cotrimoxazole referral recommended whodefined severe pneumonia difficulties referral compliance reported many lowresource settings resulting low access appropriate treatment objective study assess whether community case management lady health workers lhws oral amoxicillin children severe pneumonia equivalent current standard care methods haripur district pakistan 28 clusters randomly assigned stratification 11 ratio intervention control clusters use computergenerated randomisation sequence children included study aged 259 months whodefined severe pneumonia living study area intervention clusters communitybased lhws provided mothers oral amoxicillin 8090 mgkg per day 375 mg twice day infants aged 211 months 625 mg twice day aged 1259 months specific guidance use control clusters lhws gave first dose oral cotrimoxazole age 211 months sulfamethoxazole 200 mg plus trimethoprim 40 mg age 12 months 5 years sulfamethoxazole 300 mg plus trimethoprim 60 mg referred children health facility standard care participants carers assessors masked treatment assignment primary outcome treatment failure day 6 analysis per protocol adjustment clustering within groups use generalised estimating equations study registered number isrctn10618300 findings assigned 1995 children treatment 14 intervention clusters 1477 14 control clusters analysed 1857 1354 children respectively clusteradjusted treatment failure rates day 6 significantly reduced intervention clusters 165 9 vs 241 18 risk difference 89 95 ci 124 54 adjustment baseline covariates made little difference 73 101 45 two deaths reported control clusters one intervention cluster risk reduction occurrence fever lower chest indrawing day 3 67 100 33 adverse events diarrhoea n4 skin rash n1 intervention clusters diarrhoea n3 control clusters interpretation community case management could result standardised treatment children severe pneumonia reduce delay treatment initiation reduce costs families healthcare systems funding united states agency international development usaid
https://doi.org/10.1046/j.1365-3156.2001.00786.x
Amy Iversen|Lauren van Staden|Jamie Hacker Hughes|Tess Browne|Neil Greenberg|Matthew Hotopf|Roberto J. Rona|Simon Wessely|Graham Thornicroft|Nicola T. Fear
Help-seeking and receipt of treatment among UK service personnel
2,010
King's College London|King's College London|King's College London|King's College London|King's College London|King's College London|King's College London|King's College London|King's College London|King's College London
background armed forces personnel data helpseeking behaviour receipt treatment mental disorders important research policy aims examine mental healthcare service use receipt treatment sample uk military method participants drawn existing uk military health cohort sample stratified reserve status participation main warfighting period iraq war participants completed telephonebased structured diagnostic interview comprising patient health questionnaire primary care posttraumatic stress disorder screen pcptsd series questions service utilisation treatment receipt results 23 common mental disorders still serving military receiving form medical professional help nonmedical sources help chaplains widely used among regular personnel receipt professional help seen primary care 79 common treatment medication counsellingpsychotherapy regular personnel receiving cognitivebehavioural therapy cbt findings comparable reported general population conclusions uk armed forces majority mental disorders currently seeking medical help symptoms work understand barriers care important timely given group risk occupational psychiatric injury
https://doi.org/10.1111/j.1365-2133.2010.10067.x
I Shrestha|Bikash Lal Shrestha|R Amatya
Analysis of Ear, Nose and Throat Foreign Bodies in Dhulikhel Hospital
2,013
Dhulikhel Hospital|Kathmandu University|Dhulikhel Hospital|Kathmandu University|Dhulikhel Hospital|Kathmandu University
background foreign body ear nose throat commonly encountered otolaryngologists pediatricians primary care physicians objective aim study analyze different types foreign bodies sociodemographic correlates selfinflicted foreign body insertion earnosethroat method two year hospital based cross sectional descriptive study performed department ear nose throat ent dhulikhel hospital kathmandu university june 2009 june 2011 verification institutional review committee using predesigned questionnaire sociodemographic data collected prospectively examining clinically patients attending foreign body interviewing caregivers pediatric patients removal foreign body data collected 312 patients entered analyzed using descriptive analytical statistical methods using spss version 160 results mean age 2126 years majority 010 years 506 male predominance noted 5897 patients caregivers illiterate 351 literacy primary level2112foreign body ear found frequent 474 mostly nonliving 961 patients presented late 80 history prior attempted removal 67 pearsons chi square test education level duration time significant p value 00000 one way anova test type foreign body age significant p value 0001 conclusion foreign bodies common adult pediatric ear nose throat potentially associated significant complications taken care immediately kathmandu university medical journal vol10 2 issue 38 apr june 2012 page 48 doi httpdxdoiorg103126kumjv10i27334
https://doi.org/10.1371/journal.pone.0037927
null
null
2,021
University of Glasgow|University of Glasgow|University of Glasgow|University of Glasgow
background general practice websites increasingly important point interaction readability largely unexplored one four adults struggle basic literacy socioeconomic gradient readable content prerequisite promoting health literacy aim assess general practice website readability analysing text design factors assess whether practices adapted website text likely literacy levels populations design setting websites general practices across scotland analysed march december 2019 using crosssectional design method text extracted five webpages per website eight text readability factors measured including flesch reading ease fleschkincaid grade level relationship readability practice populations level deprivation measured using scottish index multiple deprivation simd assessed overall 10 design factors contributing readability accessibility scored results total 864 n 813941 scottish practices website 229 n 8743823 webpages written governmentrecommended reading level online content 914 years old content remaining websites 771 n 29493823 suitable higher reading age webpages 805 n 30773823 recommended level easytounderstand plain english statistically significant association webpage reading age simd 67 n 51764 websites achieved design accessibility recommendations conclusion changes practice websites could improve readability promote health literacy practices need financial resources ongoing technical support achieved maintained failure provide readable accessible websites may widen health inequalities topic become increasingly important online service use accelerates
https://doi.org/10.2196/18835
Amanda R. Johnston|Thomas R. Gillespie|Innocent B. Rwego|Traci L. Tranby McLachlan|Angela D. Kent|Tony L. Goldberg
Molecular Epidemiology of Cross-Species Giardia duodenalis Transmission in Western Uganda
2,010
University of Illinois Urbana-Champaign|Emory University|Makerere University|University of Illinois Urbana-Champaign|Illinois Department of Natural Resources|University of Illinois Urbana-Champaign|University of Wisconsin Health|Center for Global Health|University of Wisconsin–Madison|Makerere University
background giardia duodenalis prevalent tropical settings diverse opportunities exist transmission people animals conducted crosssectional study g duodenalis people livestock wild primates near kibale national park uganda humanlivestockwildlife interaction high due habitat disturbance goal infer crossspecies transmission potential g duodenalis using molecular methods investigate clinical consequences infection methodologyprincipal findings realtime pcr dna extracted fecal samples revealed combined prevalence g duodenalis people three villages 44108 407 prevalence reaching 675 one village prevalence rates livestock primates 124 111 respectively age associated g duodenalis infection people higher prevalence individuals 15 years livestock higher prevalence subadult versus adult animals potential risk factors people gender contact domestic animals working fields working forests source drinking water medication use g duodenalis infection associated gastrointestinal symptoms people clinical disease noted livestock primates sequence analysis four g duodenalis genes identified assemblage aii humans assemblage biv humans endangered red colobus monkeys assemblage e livestock red colobus representing first documentation assemblage e nonhuman primate addition genetic relationships within biv assemblage revealed subclades identical g duodenalis sequences humans red colobus conclusionssignificance finding g duodenalis people primates assemblage biv livestock primates assemblage e underscores crossspecies transmission multiple g duodenalis assemblages may occur locations western uganda people livestock primates overlap use habitat data also demonstrate high locally variable prevalence g duodenalis people western uganda little evidence associated clinical disease reverse zoonotic g duodenalis transmission may particularly frequent tropical settings anthropogenic habitat disturbance forces people livestock interact high rates wildlife could negative consequences wildlife conservation
https://doi.org/10.2196/24531
Pauline Ducrot|Ilaria Montagni|Viêt Nguyen?Thanh|Anne-Juliette Serry|Jean-Baptiste Richard
Evolution of Online Health-Related Information Seeking in France From 2010 to 2017: Results From Nationally Representative Surveys
2,021
Santé Publique France|Bordeaux Population Health|Inserm|University of Bordeaux|Santé Publique France|Santé Publique France|Santé Publique France
background given rapid ongoing progression internet increase health information available disparate online sources important understand changes impact online health informationseeking behavior population way managing ones health objective paper aims describing evolution internet use source health information 2010 2017 well characteristics online health information seekers topics interest sources information trust retrieved information potential impact behavior methods data french nationally representative surveys health barometers used n4141 2010 4811 2014 6255 2017 evolutions time assessed using chisquare tests associations sociodemographic characteristics health status evaluated using logistic regression models results use internet source health information rose 2010 2014 373 679 plt001 decreased significantly 2017 603 plt001 overall profile health information seekers compared nonseekers change time likely women younger higher educational level higher household income executives 2014 2017 proportion pay attention source information significantly increased reach 397 plt001 2017 2014 general healthrelated websites remained first source information 386 institutional websites third source 81 information seekers trusted information found online 2010 80 slight decrease 2014 2017 p048 among individual characteristics trust information main determinant way managing ones health odds ratio 406 95 ci 326506 conclusions rapid growth internet use seeking health information 2010 2014 period decrease recorded 2017 parallel decrease trust quality reliability information found online findings underline need public health authorities increase citizens ehealth literacy provide alternative trustworthy sources combining popularity accessibility general health information websites
https://doi.org/10.1093/geroni/igx004.4486
Fantahun Ayenew Mekonnen|Yohannes Abere Ambaw|Genanew Timerga Neri
Socio-economic determinants of anemia in pregnancy in North Shoa Zone, Ethiopia
2,018
University of Gondar|Bahir Dar University|Debre Berhan University
background globally anemia pregnancy increases maternal fetal neonatal mortality morbidity according 2011 ethiopian demographic health survey 22 pregnant women ethiopia reported anemic however since ethiopian population diverse regard culture religion characteristics evidence may represent condition study area aimed determine prevalence anemia associated factors among women receiving antenatal care anc debre berhan town hospitals clinics methods conducted institution based cross sectional study among women receiving anc hospitals clinics debre berhan town ethiopia september november 2013 antenatal care providers respective health facilities collected data interview observation using closed openended questions computed frequencies percentages describe data performed bivariate multivariable binary logistic regression analyses identify factors associated anemia pregnancy stata version 12 used carry analyses results total 295 participants completed study response rate 89 study demonstrated 10 prevalence anemia 643 32 4 respondents mild moderate severe anemia respectively anemia statistically significantly associated education occupation conclusion prevalence anemia study area lower previous studies findings literacy job status women predictors anemia pregnancy since study conducted women opportunity visit health facilities valuable conduct community based research better understand problem study area thus propose future deliverable
https://doi.org/10.1002/cncr.31076
Yohannes Gebreegziabher|Eshetu Girma|Markos Tesfaye
Help-seeking behavior of Jimma university students with common mental disorders: A cross-sectional study
2,019
Debre Berhan University|Addis Ababa University|St. Paul's Hospital Millennium Medical College
background globally mental health helpseeking behavior university students reported poor less onethird university students common mental disorders cmds report sought help formal sources failure seek treatment associated prolonged disability poor mental health outcomes including suicide ethiopia little known helpseeking behavior university students cmds objective study aimed assess prevalence determinants help seeking sources help sought jimma university undergraduate students cmds method seven hundred sixty students selected participate crosssectional study using multistage sampling sources help identified using actual helpseeking questionnaire cmds assessed using 10item kessler psychological distress scale binary logistic regression analysis used univariate multivariable analysis results sampled students 584 found current cmds current cmds 784 sought help problems majority 838 participants sought help informal sources compared students good overall levels satisfaction life good fair poor poor overall level satisfaction life less likely seek help pvalue 0021 0014 0011 respectively lastly previous history helpseeking significantly associated seeking help cmds pvalue0001 conclusion half jimma university students found high risk cmds majority cmds sought help informal sources future studies needed explore barriers seeking help formal resources effects receiving help formal sources cmds symptoms
https://doi.org/10.1007/s11999-016-5140-5
Mulugeta Tarekegn Angamo|Belete Habte Melese|Wubeante Yenet Ayen
Determinants of Glycemic Control among Insulin Treated Diabetic Patients in Southwest Ethiopia: Hospital Based Cross Sectional Study
2,013
Jimma University|Jimma University|Jimma University
background good glycemic control reduces risk diabetic complications despite achieving good glycemic control remains challenge diabetic patients objective study identify determinants glycemic control among insulin treated diabetic patients jimma university hospital southwest ethiopia methods hospitalbased crosssectional study conducted systematically sampled 284 insulintreated diabetic patients regular follow data collected interviewing patients hospital visits reviewing respective databases september 2010 december 2011 data collection took place february 20 may 20 2012 poor glycemic control defined fasting blood sugar fbs 126 mgdl binary logistic regression analysis conducted identify predictors poor glycemic control results patients mean age 4137 1508 years 585 males mean duration insulin treatment 49 51 years 183 achieved good glycemic control fbs126 mgdl 95 selfreported repeated use disposable insulin syringeneedle 48 correctly rotating insulin injection sites 831 study participants one complications multivariable logistic regression analyses body weight 70 kg aor 021 p0001 total daily dose insulin 35 iuday aor 026 p0001 total daily dose variation without checking glycemic level aor 339 p 0020 knowledge deficit signs symptoms hyperglycemia aor 360 p 0004 nonadherence dietary management aor 035 p 0005 independent predictors poor glycemic control conclusions proportion patients poor glycemic control high resulted development one complications regardless duration insulin treatment hence appropriate management patients focusing relevant associated factors independent predictors poor glycemic control would great benefit glycemic control
https://doi.org/10.1371/journal.pone.0083822
Genevieve Coorey|David Peiris|Anish Scaria|John C. Mulley|Lis Neubeck|Nashid Hafiz|Julie Redfern
An Internet-Based Intervention for Cardiovascular Disease Management Integrated With Primary Care Electronic Health Records: Mixed Methods Evaluation of Implementation Fidelity and User Engagement
2,021
University of Sydney|The George Institute for Global Health|UNSW Sydney|The George Institute for Global Health|The George Institute for Global Health|The George Institute for Global Health|Edinburgh Napier University|University of Sydney|University of Sydney|University of Sydney
background growing evidence supports benefits ehealth interventions increase patient engagement improve outcomes range conditions however ineffective program delivery usage attrition limit exposure interventions may reduce effectiveness objective study aims evaluate delivery fidelity ehealth intervention describe use patterns compare outcomes low high users identify mediating factors intervention delivery receipt methods mixed methods study internetbased intervention evaluated effectiveness randomized controlled trial rct intervention comprised medication cardiovascular disease cvd risk data uploaded primary care electronic health record ehr interactive personalized cvd risk score estimation goal setting selfmonitoring interactive social forum optional receipt heart health messages fidelity assessed 12 months trial outcomes compared low high users data sources included program delivery records web log data trial data thematic analysis communication records results participants intervention group 451486 93 initial training session conducted telephone 413447 924 participants trained mean duration 44 minutes range 1090 minutes staff conducted 9845 17761804 expected followups mostly telephone email 451 participants commenced logins 468 211 categorized low users defined least one login 3 fewer months followup 404 182 categorized high users least one login 3 months followup 128 58 nonadopters logins training session mean login frequency 34 per month ongoing users significant difference groups primary trial outcome adherence guidelinerecommended medications p44 unadjusted analyses high users significantly greater ehealth literacy scores p003 likely meet recommended weekly targets fruit p03 fish p004 servings however adjusted findings significant interactive screen use highest goal tracking lowest chat forum screens ehrderived data held early interest users fidelity measures reach content dose delivered dose received influenced facilitation strategies used staff invisible qualities staffparticipant communication participants responsiveness intervention attributes conclusions multifeature internetbased intervention delivered high fidelity rct protocol regularly used 404 182451 users 12 months higher login frequency indicator greater intervention exposure associated statistically significant improvements ehealth literacy scores lifestyle changes clinical outcomes attributes intervention individualized support influenced initial ongoing use
https://doi.org/10.1192/bjp.179.4.361
Lori B. Daniels|Paul Clopton|Gail A. Laughlin|Alan S. Maisel|Elizabeth Barrett?Connor
Growth-Differentiation Factor-15 Is a Robust, Independent Predictor of 11-Year Mortality Risk in Community-Dwelling Older Adults
2,011
VA San Diego Healthcare System|VA San Diego Healthcare System|VA San Diego Healthcare System|VA San Diego Healthcare System|VA San Diego Healthcare System
background growthdifferentiation factor15 gdf15 emerging prognostic marker patients cardiovascular disease cvd prognostic value communitydwelling adults reported hypothesized gdf15 would add incremental power prediction mortality population communitydwelling older adults without known heart disease methods results measured plasma gdf15 nterminal probtype natriuretic peptide ntprobnp creactive protein levels 1391 rancho bernardo study participants mean age 70 years history cvd followed mean 11 years models adjusted traditional cvd risk factors gdf15 robust predictor allcause cardiovascular noncardiovascular mortality gdf15 stronger predictor allcause mortality either ntprobnp creactive protein hazard ratio 95 confidence interval per sd log 10 units 15 13 18 p lt00001 gdf15 versus 13 12 15 p lt00001 ntprobnp creactive protein significant predictor among biomarkers considered gdf15 predicted noncardiovascular death hazard ratio 16 14 20 p lt00001 growth differentiation factor15 improved discrimination modestly significantly improved reclassification allcause noncardiovascular mortality borderline improvement cardiovascular mortality ntprobnp significantly improved reclassification allcause cardiovascular mortality creactive protein improve reclassification end point tested participants highest quartile gdf15 ntprobnp increased risk death compared participants ntprobnp elevated hazard ratio 15 11 20 p 001 conclusions growth differentiation factor15 strong predictor allcause cardiovascular noncardiovascular mortality communitydwelling older individuals adding incremental value traditional risk factors ntprobnp creactive protein levels
https://doi.org/10.1371/journal.pone.0005166
Jacob A. Doll|W. Schuyler Jones|Yuliya Lokhnygina|Sara Culpepper|Robin L. Parks|Christy Calhoun|David H. Au|Manesh R. Patel
PREPARED Study: A Study of Shared Decision-Making for Coronary Artery Disease
2,019
VA Puget Sound Health Care System|University of Washington|Duke University|Clinical Research Institute|Duke University|Clinical Research Institute|Healthwise|Healthwise|VA Puget Sound Health Care System|Duke University|Clinical Research Institute
background guidelines recommend patient engagement shared decisionmaking regarding coronary revascularization studies demonstrate poor patient understanding risks benefits alternatives effective strategies needed integrate informed patient preferences clinical care particularly patients undergoing diagnostic coronary angiography methods results developed webbased decision aid educate patients survey treatment preferences angiography compared knowledge attitudes preferences 203 patients without use decision aid pilot clusterrandomized study cardiologists assigned receive versus receive patient preferences subsequent assessment treatment decisions median age participants 64 years 62 men 74 white similar number acute presentation 49 nonstsegmentelevation myocardial infarction unstable angina stable presentation 51 stable angina atypical symptoms patients preferred treatment percutaneous coronary intervention compared either medical therapy alone 63 versus 21 coronary artery bypass graft surgery 81 versus 7 decision aid associated improved performance 6item knowledge scale mean 27 versus 22 questions correct p001 greater interest shared decisionmaking overall change patient preferences pilot clusterrandomized study demonstrated feasibility integrating patient preference information clinical care although providing preferences clinicians improve concordance preference treatment conclusions webbased decision aid associated improved patient knowledge greater desire participate shared decisionmaking coronary revascularization patients preferred percutaneous coronary intervention either medical therapy alone coronary artery bypass graft surgery investigation needed determine impact patient preferences clinical decisionmaking outcomes clinical trial registration url httpswwwclinicaltrialsgov unique identifier nct02272062
https://doi.org/10.1371/journal.pone.0179865
J. T. Jabbour|Chris Milross|Puma Sundaresan|Ardalan Ebrahimi|Lisa Beatty|Haryana M. Dhillon|Gary J. Morgan|Bruce Ashford|Muzib Abdul?Razak|Eva Wong|Michael Veness|Carsten E. Palme|Cate Froggatt|Ruben D. Cohen|Rafael Ekmejian|Jessica Tay|David Roshan|Jonathan R. Clark
Education and support needs in patients with head and neck cancer: A multi?institutional survey
2,017
University of Sydney|Chris O’Brien Lifehouse|University of Sydney|University of Sydney|Westmead Hospital|Liverpool Hospital|University of Sydney|Cooperative Trials Group for Neuro-Oncology|University of Sydney|Cooperative Trials Group for Neuro-Oncology|Westmead Hospital|Wollongong Hospital|Westmead Hospital|Westmead Hospital|University of Sydney|Westmead Hospital|Westmead Hospital|Chris O’Brien Lifehouse|Liverpool Hospital|UNSW Sydney|University of New England|UNSW Sydney|University of Sydney|Chris O’Brien Lifehouse|UNSW Sydney
background head neck cancer hnc encompasses diverse group tumors thus providing appropriate tailored information patients treatment challenge objective current study characterize experience unmet needs patients hnc regard information support provision methods 28question crosssectional survey completed patients treated hnc 1 4 institutions new south wales australia chris obrien lifehouse liverpool westmead wollongong hospitals consisted adapted kessler psychological distress scale questions assessing information quality quantity format results total 597 patients responded mean age patients 58 years range 2194 years 284 men 313 women 111 majority patients reported information concerning disease process 76 prognosis 67 treatment 77 sufficient approximately 50 reporting received little information regarding coping stress anxiety substantial percentage patients reported receiving minimal information concerning psychosexual health 56 availability patient support groups 56 majority patients preferred access multiple modes information delivery 72 preferred modality oneonone meetings health educator 37 followed internetbased written information 19 conclusions patients hnc diverse group complex educational support needs patients appear given information regarding survivorship topics psychological wellbeing patient support groups psychosexual health less frequently information concerning disease treatment verbal communication needs reinforced accessible wellconstructed written multimedia resources appropriate patients educational level cancer 201712319491957 2017 american cancer society
https://doi.org/10.1136/bmjgh-2020-002314
Josefin Wångdahl|Karuna Dahlberg|Maria Jaensson|Ulrica Nilsson
Arabic Version of the Electronic Health Literacy Scale in Arabic-Speaking Individuals in Sweden: Prospective Psychometric Evaluation Study
2,021
Karolinska Institutet|Uppsala University|Örebro University|Örebro University|Karolinska Institutet|Karolinska University Hospital
background health information often communicated internet vital end user range digital skills well understand information promote health valid reliable 8item instrument electronic health literacy scale eheals evaluates skills number arabicspeaking people migrating sweden parts world increasing due unstable military political situations countries origin poor health limited health literacy described population sweden still knowledge arabic version eheals tested validity reliability thus arabicspeaking populations sweden cannot included studies measuring ehealth literacy support equal treatment health care objective aim study translate adapt original english eheals version arabic evaluate psychometric properties methods eheals rigorously translated adapted evaluated content validity conducted prospective psychometric evaluation natively arabicspeaking participants living sweden construct validity factor structure internal consistency testretest reliability evaluated using spearman correlation principal component analysis cronbach weighted quadratic cohen respectively results study population consisted arabicspeaking participants n298 age mean 418 years sd 105 construct validity supported weak moderate correlations principal component factor analysis revealed onefactor structure internal consistency high cronbach 092 testretest reliability acceptable weighted quadratic cohen 076 evaluation indicated ehealth literacy threshold values dichotomized limited sufficient rather trichotomized inadequate problematic sufficient conclusions arabic version eheals unidimensional scale valid reliable measuring ehealth literacy among natively arabicspeaking people sweden found acceptable feasible general population
https://doi.org/10.2196/16095
Karthik Adapa|Saumya Jain|Richa Kanwar|Tanzila Zaman|Trusha Taneja|Jennifer Walker|?ukasz Mazur
Augmented reality in patient education and health literacy: a scoping review protocol
2,020
University of North Carolina System|University of North Carolina System|University of North Carolina System|University of North Carolina System|University of North Carolina System|University of North Carolina System|University of North Carolina System
background health literacy enables patients understanding basic healthcare information taking informed health decisions thus desirable goal healthcare system increases patients adherence treatment improves quality care eases overall burden healthcare system recent years technological solutions increasingly used educating patients achieving better health literacy augmented reality ar provides powerful contextual situated learning experiences supplements real world virtual objects ar could potentially effective learning methodology patients thus warranting comprehensive overview current state ar patient education health literacy methods proposed scoping review based framework developed arksey omalley including refinements suggested levac et al systematic search references published literature conducted nine research databasesinstitute electrical electronics engineers ieee cumulative index nursing allied health literature cinahl pubmed psycinfo embase web science scopus association computing machinery acm association information systems elibrary aisel unpublished studies proquest dissertations theses conference proceedings citation index grey literature references obtained web search also included databases searched inception 14 january 2020 two independent reviewers screen studies search results two successive stages titleabstract screening followed fulltext screening data variables extracted selected studies characterise study design type ar technology employed relational factors affecting patient education lastly key stakeholders consulted gather insights study findings ethics dissemination results disseminated stakeholder meetings conference presentations data used publicly available secondary sources study require ethical review
https://doi.org/10.1002/cncr.29759
Susan Robinson|Debra K. Moser|Michele M. Pelter|Thomas S. Nesbitt|Steven M. Paul|Kathleen Dracup
Assessing Health Literacy in Heart Failure Patients
2,011
University of California, San Francisco|University of Kentucky|University of Nevada Reno|University of California, Davis|University of California, San Francisco|University of California, San Francisco
background health literacy important implications health interventions clinical outcomes shortened test functional health literacy adults stofhla timed test used assess health literacy many clinical populations however usefulness heart failure hf patients many elderly compromised cognitive function unknown investigated relationship stofhla total score recommended 7minute limit time limit ntl methods results enrolled 612 ruraldwelling adults hf mean age 660 130 years 588 male characteristics affecting health literacy identified multiple regression percentage correct scores improved 71 86 mean percent change 151 181 7minute ntl scores twentyseven percent patients improved 1 literacy level ntl scores p 001 demographic variables explained 242 111 variance correct scores 7minute ntl scores respectively female gender younger age higher education higher income related higher scores conclusion patients hf may inaccurately categorized low marginal health literacy stofhla time limits enforced new ways assess health literacy older adults needed
https://doi.org/10.2196/15520
Ebtihal Alsaad|Sharifah Abdullah AlDossary
Educational Video Intervention to Improve Health Misinformation Identification on WhatsApp Among Saudi Arabian Population: Pre-Post Intervention Study
2,024
King Saud bin Abdulaziz University for Health Sciences|King Abdullah International Medical Research Center|King Saud bin Abdulaziz University for Health Sciences|King Abdullah International Medical Research Center
background health misinformation adversely affect individuals quality life increase risk mortality people often fail assess content messages sharing internet increasing spread misinformation problem exacerbated growing variety digital information environments especially social media presents effective platform spreading misinformation due rapid informationsharing capabilities educational interventions developed help consumers verify validity digital health information however tools designed detect health misinformation social media content validated given increased use social media platforms particularly whatsapp crucial develop tools help consumers assess credibility messages detect misinformation objective main objective study develop assess educational tool aimed educating consumers detecting health misinformation whatsapp secondary objective assess association demographic factors knowledge levels methods study used singlearm prepost intervention design evaluate effectiveness educational video improving participants ability detect healthrelated misinformation whatsapp messages first phase educational video intervention developed validated second phase participants invited complete webbased survey consisted preevaluation questions followed educational video intervention subsequently asked answer questions postevaluation questions results webbased survey received 485 responses completion rate 996 n483 statistically significant associations existed knowledge level age gender employment region residence plt05 video intervention elicit statistically significant change participants abilities identify misinformation whatsapp messages z6887 plt001 viewing video associated increased knowledge following concepts checking forwarded label plt001 looking spelling grammatical errors plt001 analyzing facts p03 checking links p002 p001 assessing photos videos plt001 statistically significant difference knowledge level intervention plt001 conclusions study developed evaluated effectiveness educational video intervention improve health misinformation identification whatsapp among saudi arabian population results indicate educational videos valuable tools improving participants abilities identify misinformation outcomes research contribute understanding constitutes effective tool enhancing health misinformation awareness interventions may particularly useful combating misinformation among arabicspeaking populations whatsapp may ultimately improve ehealth literacy limiting prevalence impact misinformation allows people make betterinformed health decisions
https://doi.org/10.1371/journal.pone.0003182
Sharon LaForest|Sheryl L. Chow|Robert J. DiDomenico|Kathleen Dracup|Christopher R. Ensor|Wendy Gattis?Stough|J. Thomas Heywood|JoAnn Lindenfeld|Robert L. Page|J. Herbert Patterson|Orly Vardeny|Barry M. Massie
Clinical Pharmacy Services in Heart Failure: An Opinion Paper From the Heart Failure Society of America and American College of Clinical Pharmacy Cardiology Practice and Research Network
2,013
Louis Stokes Cleveland VA Medical Center|Western University of Health Sciences|University of Illinois at Chicago|University of California, San Francisco|University of Pittsburgh|Campbell University|Scripps Clinic|University of Colorado Denver|University of Colorado Denver|University of North Carolina at Chapel Hill|University of Wisconsin–Madison|San Francisco VA Medical Center
background heart failure hf care takes place multiple settings variety providers generally involves patients multiple comorbidities situation perfect storm factors predispose patients medication errors methods results goals paper outline potential roles clinical pharmacists multidisciplinary hf team document outcomes associated interventions clinical pharmacists recommend minimum training clinical pharmacists engaged hf care suggest financial strategies support clinical pharmacy services within multidisciplinary team patients transition inpatient outpatient settings multiple caregivers pharmacists positively affect medication reconciliation education assure consistency management results improvements patient satisfaction medication adherence reduce medication errors mechanical circulatory support heart transplant teams centers medicare medicaid services considers participation transplant pharmacology expert eg clinical pharmacist requirement accreditation given highly specialized complex drug regimens used although reports outcomes pharmacist interventions mixed owing differences study design benefits increased use evidencebased therapies decreases hf hospitalizations emergency department visits decreases allcause readmissions demonstrated clinical pharmacists participating hf heart transplant teams completed specialized postdoctoral training form residencies andor fellowships cardiovascular andor transplant pharmacotherapy board certification recommended financial mechanisms support pharmacist participation hf teams variable conclusions positive outcomes associated clinical pharmacist activities support value making resource available hf teams
https://doi.org/10.2196/20457
Rongbin Xu|Qi Zhao|Micheline de Sousa Zanotti Stagliorio Coélho|Paulo Hilário Nascimento Saldiva|Michael J. Abramson|Shanshan Li|Hyewon Lee
Socioeconomic level and associations between heat exposure and all-cause and cause-specific hospitalization in 1,814 Brazilian cities: A nationwide case-crossover study
2,020
Binzhou University|Binzhou Medical University|Monash University|Monash University|Universidade de São Paulo|Universidade de São Paulo|Monash University|Monash University|Monash University|Binzhou University|Binzhou Medical University
background heat exposure increase global warming linked increased risk range types causespecific hospitalizations however little known socioeconomic disparities vulnerability heat aimed evaluate whether socioeconomic disparities vulnerability heatrelated allcause causespecific hospitalization among brazilian cities methods findings collected daily hospitalization weather data hot season cityspecific 4 adjacent hottest months year 20002015 1814 brazilian cities covering 784 brazilian population timestratified casecrossover design modeled quasipoisson regression distributed lag model used estimate cityspecific heathospitalization association metaanalysis used synthesize cityspecific estimates according different socioeconomic quartiles levels included 49 million hospitalizations 585 female median interquartile range age 333 198557 years cities lower middle income lmi upper middle income umi high income hi according world banks classification every 5c increase daily mean temperature hot season associated 51 95 ci 4457 p 0001 37 3340 p 0001 26 1734 p 0001 increase allcause hospitalization respectively intercity socioeconomic disparities association strongest children adolescents 019 years increased allcause hospitalization risk every 5c increase 95 ci 99 87111 p 0001 lmi cities versus 52 4163 p 0001 hi cities disparities particularly evident hospitalization due certain diseases including ischemic heart disease increase causespecific hospitalization risk every 5c increase 95 ci 56 02 118 p 0060 lmi cities versus 05 21 31 p 0717 hi cities asthma 37 0371 p 0031 versus 64 121 03 p 0041 pneumonia 80 56104 p 0001 versus 38 1165 p 0005 renal diseases 96 62131 p 0001 versus 49 1880 p 0002 mental health conditions 172 84268 p 0001 versus 55 14 130 p 0121 neoplasms 31 0755 p 0011 versus 01 21 20 p 0939 disparities similar stratifying cities socioeconomic indicators urbanization rate literacy rate household income main limitations lack data personal exposure temperature citylevel analysis assess intracity individuallevel socioeconomic disparities could exclude confounding effects unmeasured variables conclusions less developed cities displayed stronger associations heat exposure allcause hospitalizations certain types causespecific hospitalizations brazil may exacerbate existing geographical health socioeconomic inequalities changing climate
https://doi.org/10.1002/cncr.30207
Marcus Bendtsen|Ulrika Müssener|Catharina Linderoth|Kristin Thomas
A Mobile Health Intervention for Mental Health Promotion Among University Students: Randomized Controlled Trial
2,020
Linköping University|Linköping University|Linköping University|Linköping University
background high positive mental health including ability cope normal stresses life work productively able contribute ones community associated various health outcomes role positive mental health therefore increasingly recognized national mental health promotion programs policies mobile health mhealth interventions could costeffective way disseminate positive psychological interventions general population objective aim study estimate effect fully automated mhealth intervention positive mental health anxiety depression symptomology among swedish university students using randomized controlled trial design methods 2arm singleblind researchers parallelgroups randomized controlled trial mhealth positive psychology program intervention group relevant online mental health information control group employed estimate effect novel intervention participants recruited using digital advertising student health care centers sweden inclusion criteria 1 university students 2 able read understand swedish 3 access mobile phone exclusion criteria high positive mental health assessed mental health continuum short form mhcsf high depression anxiety symptomology assessed hospital anxiety depression scale hads primary outcome positive mental health mhcsf secondary outcomes depression anxiety symptomatology hads subscales mhcsf also analyzed exploratory outcomes outcomes measured 3 months randomization questionnaires completed participants mobile phones results total 654 participants median age 25 years including 510 780 identifying female randomized either intervention n348 control group n306 followup positive mental health significantly higher intervention group compared control group incidence rate ratio irr1067 95 ci 10241112 p002 depression anxiety symptomatology intervention group showed significantly lower scores followup compared control group depression irr0820 95 ci 07140942 p005 anxiety irr0899 95 ci 08400962 p002 followup rates lower expected 583 primary outcomes 523 secondary outcomes however attrition analyses identify systematic attrition respect baseline variables conclusions mhealth intervention estimated superior usual care increasing positive mental health among university students protective effect intervention also found depressive anxiety symptoms findings demonstrate feasibility using automated mobile phone format enhance positive mental health offers promise use mhealth solutions public mental health promotion trial registration international standard randomized controlled trial registry isrctn54748632 httpwwwisrctncomisrctn54748632
https://doi.org/10.1371/journal.pone.0095829
Martin S. Hagger|Sarah J. Hardcastle|Miao Hu|See Kwok|Jianping Lin|Hapizah Nawawi|Jing Pang|Raul D. Santos|Handrean Soran|Ta-Chen Su|Brian Tomlinson|Gerald F. Watts
Health literacy in familial hypercholesterolemia: A cross-national study
2,018
Curtin University|University of Jyväskylä|Griffith University|Curtin University|Chinese University of Hong Kong|Manchester University NHS Foundation Trust|University of Manchester|Beijing Anzhen Hospital|Capital Medical University|Universiti Teknologi MARA|University of Western Australia|Universidade de São Paulo|Manchester University NHS Foundation Trust|National Taiwan University Hospital|Chinese University of Hong Kong|University of Western Australia|Royal Perth Hospital
background high rates inadequate health literacy associated maladaptive health outcomes chronic disease including increased mortality morbidity rates poor treatment adherence poor health adequate health literacy may important factor effective treatment management familial hypercholesterolemia may also implicated genetic screening familial hypercholesterolemia among index cases present study examined prevalence predictors health literacy familial hypercholesterolemia patients attending clinics seven countries design crosssectional survey methods consecutive fh patients attending clinics australia brazil china hong kong malaysia taiwan uk completed measures demographic variables age gender household income highest education level brief threeitem health literacy scale results rates inadequate health literacy lowest uk 70 australia 100 hong kong 157 taiwan 180 samples higher rates brazil 220 malaysia 250 china 370 samples income independent predictor health literacy levels accounting effects age health literacy also independently related china national group membership conclusions findings indicate nontrivial levels inadequate health literacy samples familial hypercholesterolemia patients consistent previous research chronic illness inadequate health literacy related income index health disparities chinese familial hypercholesterolemia patients likely high rates inadequate health literacy independent income current findings highlight imperative education interventions targeting familial hypercholesterolemia patients inadequate health literacy
https://doi.org/10.1002/14651858.cd004538.pub2
Jing Zhao|Fujian Song|Shuhua Ren|Yan Wang|Liang Wang|Wei Liu|Ying Wan|Hong Xu|Tao Zhou|Tian Hu|Lydia A. Bazzano|Yi Sun
Predictors of Condom Use Behaviors Based on the Health Belief Model (HBM) among Female Sex Workers: A Cross-Sectional Study in Hubei Province, China
2,012
Huazhong University of Science and Technology|University of East Anglia|Huazhong University of Science and Technology|Huazhong University of Science and Technology|Huazhong University of Science and Technology|Huazhong University of Science and Technology|Huazhong University of Science and Technology|Huazhong University of Science and Technology|Huazhong University of Science and Technology|Tulane University|Tulane University|Huazhong University of Science and Technology
background hiv infection related commercial sexual contact serious public health issue china objectives present study explore predictors condom use among female sex workers fsws china examine relationship health belief model hbm constructs methodologyprincipal findings crosssectional study conducted two cities wuhan suizhou hubei province china july 2009 june 2010 total 427 fsws recruited mediators lowtier entertainment establishments data obtained selfadministered questionnaires structural equation models constructed examine association collected 363 valid questionnaires within context hbm perceived severity hiv mediated perceived benefits condom use weak effect condom use r 007 perceived benefits perceived barriers proximate determinants condom use r 023 r 062 respectively selfefficacy direct effect perceived severity perceived benefits perceived barriers indirectly associated condom use behaviors r 036 conclusionssignificance hbm provides useful framework investigating predictors condom use behaviors among fsws future hiv prevention interventions focus increasing perceived benefits condom use reducing barriers condoms use improving selfefficacy among fsws
https://doi.org/10.1177/1747493018790059
Michael M Chanda|Katrina F Ortblad|Magdalene Mwale|Steven Chongo|Catherine Kanchele|Nyambe Kamungoma|Andrew Fullem|Caitlin Dunn|Leah G. Barresi|Guy Harling|Till Bärnighausen|Catherine E. Oldenburg
HIV self-testing among female sex workers in Zambia: A cluster randomized controlled trial
2,017
Harvard Global Health Institute|John Snow (United States)|John Snow (United States)|Harvard University|Harvard Global Health Institute|University College London|Heidelberg University|Harvard Global Health Institute|Africa Health Research Institute|San Francisco Foundation|University of California, San Francisco
background hiv selftesting hivst may play role addressing gaps hiv testing coverage entry point hiv prevention services conducted cluster randomized trial 2 hivst distribution mechanisms compared standard care among female sex workers fsws zambia methods findings trained peer educators kapiri mposhi chirundu livingstone zambia recruited 6 fsw participants peer educatorfsw groups randomized 1 3 arms 1 delivery direct distribution oral hivst peer educator 2 coupon coupon collection oral hivst health clinicpharmacy 3 standardofcare hiv testing participants 2 hivst arms received 2 kits 1 baseline 1 10 weeks primary outcome selfreported hiv testing past month 1 4month visits hivst replace types hiv testing secondary outcomes included linkage care hivst use hivst arms adverse events participants completed questionnaires 1 4 months following peer educator interventions 965 participants enrolled september 16 october 12 2016 delivery n 316 coupon n 329 standard care n 320 20 never tested hiv overall hiv testing 1 month 949 delivery arm 844 coupon arm 885 standardofcare arm delivery versus standard care risk ratio rr 107 95 ci 099115 p 010 coupon versus standard care rr 095 95 ci 086105 p 029 delivery versus coupon rr 113 95 ci 104122 p 0005 fourmonth rates 841 delivery arm 798 coupon arm 751 standardofcare arm delivery versus standard care rr 111 95 ci 098127 p 011 coupon versus standard care rr 106 95 ci 092122 p 042 delivery versus coupon rr 105 95 ci 094118 p 040 1 month majority hiv tests selftests 884 hiv selftest use higher delivery arm compared coupon arm rr 114 95 ci 105123 p 0001 1 month difference 4 months among participants reporting positive hiv test 1 n 144 4 months n 235 linkage care nonsignificantly lower 2 hivst arms compared standardofcare arm 4 instances intimate partner violence related study participation 3 related hiv selftest use limitations include selfreported nature study outcomes overall high uptake hiv testing conclusions study among fsws zambia found hivst acceptable accessible however hivst may substantially increase hiv cascade progression contexts overall testing linkage already high trial registration clinicaltrialsgov nct02827240
https://doi.org/10.1192/bjp.bp.106.029363
Elena Vasti|Mark J. Pletcher
Recruiting Student Health Coaches to Improve Digital Blood Pressure Management: Randomized Controlled Pilot Study
2,020
University of California, San Francisco|University of California, San Francisco
background hypertension significant problem united states affecting 1 3 adults aged 18 years associated higher risk cardiovascular disease stroke prevalence hypertension increased medically underserved areas muas mobile health technologies digital selfmonitoring devices shown improve management chronic health conditions however patients muas reduced access devices limited resources low health literacy health coaches peer training programs potentially costeffective solution shortage physicians available manage hypertension muas activating young people student health coaches shcs promising strategy improve community health objective pilot study aims assess 1 feasibility training high school students health technology coaches muas 2 whether addition shcs digital home monitoring improves frequency selfmonitoring overall blood pressure bp control methods total 15 high school students completed 3day health coach training patients documented diagnosis hypertension randomly assigned 1 3 intervention arms qardioarm alone q group provided qardioarm cuff convenience shc alone group instructed meet health coach 30 min week 5 weeks create action plans reducing bp studentqardioarm sq group received interventions results participants n27 randomly assigned 3 groups ratio 999 15 students completed training 40 615 students completed 5 meetings assigned patient barriers feasibility included transportation patient response dropoff end study overall 92 1112 students rated experience good higher 69 913 reported experience made likely go medical field statistically significant difference frequency cuff use sq vs q groups 37 vs 17 plt001 participants sq group reported better bp control intervention compared groups average bp end intervention 14584 sd 918 mm hg 15085 sd 1812 mm hg 12869 sd 2014 mm hg q sq groups respectively conclusions pilot study demonstrates feasibility pairing technology young student coaches although challenges existed sq group used cuff q group patients engaged sq group reporting higher satisfaction shc better control bp
https://doi.org/10.2196/15085
J Chataut|Ramesh Adhikari|NP Sinha
Prevalence and Risk Factors for Hypertension in Adults Living in Central Development Region of Nepal
2,012
Kathmandu University|Dhulikhel Hospital|Kathmandu University|Dhulikhel Hospital|Kathmandu University|Dhulikhel Hospital
background hypertension commonest cardiovascular disorder regarded major public health problem precursor major diseases like myocardial infarction stroke renal failure etc limited community based data hypertension nepal information prevalence hypertension population desirable objectives estimate prevalence hypertension explore risk factors associated hypertension methods cross sectional study total 527 subjects males n214 females n313 participated study age 18 years participants underwent anthropometric measurement blood pressure answered pretested questionnaire hypertension defined per jnc vii criteria results overall prevalence hypertension 224 males 327 female 153 age specific prevalence hypertension showed significant progressive increase blood pressure ranging 8 35 almost 40 hypertensives know status bivariate analysis showed significant relationship hypertension gender age literacy physical inactivity body mass index bmi smoking alcohol consumption multivariate analysis excluded literacy risk factors continued show positive association hypertension conclusion elderly less physical activity obeseoverweight smoking alcohol consumption significant risk factors hypertension therefore intervention measures warranted emphasizing modifiable risk factors smoking alcohol consumption physical activity obesity prevent hypertensionhttpdxdoiorg103126kumjv9i16255 kathmandu univ med j 2011911318
https://doi.org/10.1111/jcpp.12793
Mona Loutfy|Trevor Hart|Saira Mohammed|DeSheng Su|Edward D. Ralph|Sharon Walmsley|Lena C. Soje|Marvelous Muchenje|Anita Rachlis|Fiona Smaill|Jonathan B. Angel|Janet Raboud|Michael Silverman|Wangari Tharao|Kevin Gough|Mark H. Yudin
Fertility Desires and Intentions of HIV-Positive Women of Reproductive Age in Ontario, Canada: A Cross-Sectional Study
2,009
University of Toronto|Women's College Hospital|Public Health Ontario|University of Toronto|Toronto Metropolitan University|Women's College Hospital|University Health Network|St Joseph's Health Care|University of Toronto|University Health Network|Black Coalition for AIDS Prevention|Women's Health In Women's Hands|University of Toronto|Sunnybrook Health Science Centre|Health Sciences Centre|McMaster University Medical Centre|Hamilton Health Sciences|Ottawa Hospital|Public Health Ontario|University of Toronto|University Health Network|Lakeridge Health|Women's Health In Women's Hands|University of Toronto|St. Michael's Hospital|University of Toronto
background improvements life expectancy quality life hivpositive women coupled reduced vertical transmission likely lead numerous hivpositive women consider becoming pregnant order clarify demand aid appropriate health services planning population study aims assess fertility desires intentions hivpositive women reproductive age living ontario canada methodologyprincipal findings crosssectional study recruitment stratified match geographic distribution hivpositive women reproductive age 1852 living ontario carried women recruited 38 sites october 2007 april 2009 invited complete 189item selfadministered survey entitled hiv pregnancy planning questionnaire designed assess fertility desires intentions actions logistic regression models fit calculate unadjusted adjusted odds ratios significant predictors fertility intentions median age 490 participating hivpositive women 38 iqr 3243 61 52 47 74 born outside canada living toronto african ethnicity currently antiretroviral therapy respectively total respondents 69 95 ci 6473 desired give birth 57 95 ci 5362 intended give birth future multivariable model significant predictors fertility intentions younger age age40 p00001 african ethnicity p00001 living toronto p 0002 lower number lifetime births p 002 conclusionssignificance proportions hivpositive women reproductive age living ontario desiring intending pregnancy higher reported earlier north american studies proportions similar reported african populations healthcare providers policy makers need consider increasing services support pregnancy planning hivpositive women may particularly significant jurisdictions high levels african immigration
https://doi.org/10.1177/2396941516645251
Ramin Ravangard|Nahid Hatam|Abedin Teimourizad|Abdosaleh Jafari
Factors Affecting the Technical Efficiency of Health Systems: A Case Study of Economic Cooperation Organization (ECO) Countries (2004–10)
2,014
Shiraz University of Medical Sciences|Shiraz University of Medical Sciences|Shiraz University of Medical Sciences|Shiraz University of Medical Sciences
background improving efficiency health sector particular importance countries reach end paramount measure efficiency hand many factors affect efficiency health systems study aimed measure technical efficiency te health systems economic cooperation organization eco countries 200410 determine factors affecting te methods descriptiveanalytical panel study required data gathered using library field studies available statistics international websites completing data collection forms study te health systems 10 eco countries measured using available data data envelopment analysis dea two approaches first approach used gdp per capita education smoking inputs life expectancy infant mortality rates outputs second approach also used health expenditures per capita number physicians per thousand people number hospital beds per thousand people inputs life expectancy under5 mortality rates outputs factors affecting te health systems determined using panel data logit model excel 2010 win4deap 112 stata 110 used analyze collected data results according first approach mean te health systems 0497 based second one 0563 turkey turkmenistan respectively highest lowest mean efficiency also results panel data logit model showed gdp per capita health expenditures per capita significant relationships te health systems conclusion order maximize te health systems health policymakers pay special attention proper use healthcare resources according peoples needs appropriate management health system resources allocating adequate budgets health sector establishing appropriate referral system provide better public access health services according income needs among many others
https://doi.org/10.1371/journal.pntd.0002213
Ngozi Akwataghibe|Elijah Ogunsola|Jacqueline E. W. Broerse|Oluwafemi Popoola|Adanna I. Agbo|Marjolein Dieleman
Exploring Factors Influencing Immunization Utilization in Nigeria—A Mixed Methods Study
2,019
Royal Tropical Institute|Vrije Universiteit Amsterdam|Ondo State Primary Health Care Development Board|Vrije Universiteit Amsterdam|University of Ibadan|Morgan State University|Royal Tropical Institute|Vrije Universiteit Amsterdam
background 2005 nigeria adopted reach every ward strategy improve vaccination coverage children 023 months 2015 ogun state full coverage 12 20 local government areas eight pockets unimmunized children highest burden 37 remonorth study aimed identify factors remonorth influencing use immunization services order inform intervention approaches tackle barriers immunization utilization methods carried crosssectional study using mixed methods including survey caregivers 215 children 25 semistructured interviews stakeholders involved immunization service delivery 16 focus group discussions community men women n98 two wards ilara ipara purposively chosen study data analysed using sage working group vaccine hesitancy model results 56 children 326 172 children 9 months age immunization cards available inspection 23 596 fully immunized noticeably higher ipara ilara however immunization status assessed card recall 849 children assessed fully immunized caregivers rural ilara less knowledge vaccine schedules importance doses recognized ipara respondents 955 ilara 753 p005 community links immunization household decisionmaking patterns influenced immunization use wards migrants living hardtoreach areas disadvantaged wards health service factors like absence delivery services shortage health workers unavailability vaccines scheduled times indirect costs immunization contributed low utilization conclusion immunization utilization influenced interlinked community health services issues intervention approaches ensure communities priorities addressed actors levels involved strategies adjusted suit contexts
https://doi.org/10.1371/journal.pntd.0002927
Claire Henderson|Paul Williams|Kirsty Little|Graham Thornicroft
Mental health problems in the workplace: Changes in employers' knowledge, attitudes and practices in England 2006-2010
2,013
King's College London|King's College London|King's College London|King's College London
background 2006 shaw trust charity found high levels ignorance poor preparedness deal mental health problems among 480 senior employers uk uk government nongovernmental organisations time change ttc since provided relevant assistance employers aims examine whether improvements mental healthrelated knowledge attitudes workplace practices among british senior employers 2006 2010 method telephone survey conducted senior british employers n 480 2006 n 500 2009 2010 results increased awareness common mental health problems detected employers continued believe job candidates disclose mental health problem became less likely view colleagues attitudes barrier employing someone problem formal policies mental health use workplace accommodations became increasingly common conclusions results consistent ttc national public attitudes viewpoint survey service users 2008 2010 showed improved public attitudes mental illness reduction experiences discrimination employment
https://doi.org/10.1111/jcpp.12774
Kasemsak Jandee|Chamnong Thanapop
Food Delivery Drivers’ Health Literacy Regarding COVID-19 Prevention and Protective Behaviors During the COVID-19 Pandemic: Cross-sectional Survey in Southern Thailand
2,022
Walailak University|Walailak University
background 2019 covid19 spread worldwide causing pandemic posed unprecedented challenges pressure health systems economies food delivery services become important medium consumer food purchases limit humantohuman contact thus delivery drivers high risk exposure covid19 infection work best knowledge studies analyzed dimensions health literacy hl regarding covid19 prevention population objective study aims explore hl status toward covid19 prevention associated factors among food delivery drivers southern thailand methods following crosssectional survey july august 2021 thai food delivery drivers uppersouth lowersouth regions southern thailand recruited participate compulsory covid19 lockdown online structured questionnaire administered verbally recorded interviewer univariate multivariate linear regressions used explore independently associated factors results 401 drivers 291 726 men median age 31 years range 1964 years median number months working driver 12 months median number working hours 9 hours per day median number daily food orders 20 median daily income thai baht thb 600 us 1590 social media facebook line common source health information common information required covid19 vaccine medications treatment drivers 285401 711 excellent hl levels regarding covid19 prevention practical application information statistically correlated behavior r038 plt001 drivers lower south thailand likely excellent hl drivers 703 plt001 frequently accessed information youtube 217 p01 relatives 419 plt001 less likely excellent hl levels conclusions understanding hl among food delivery drivers would useful planning effective interventions target population conventional health education social media alone may effective educating people covid19 prevention information literacy skills could determine individuals hl drivers behaviors
https://doi.org/10.1136/jech-2018-210977
Yulei Feng|Qin Tong
Exploring the Mediating Role of Situation Awareness and Crisis Emotions Between Social Media Use and COVID-19 Protective Behaviors: Cross-Sectional Study
2,022
Shanghai Jiao Tong University|Shanghai Jiao Tong University
background outbreak infectious disease especially online media would usually important channel people get firsthand knowledge evaluate risks specific emergency although increasing attention effect social media use epidemics outbreaks relatively little known underlying mechanism social media plays role peoples cognitive affective preventive responses objective objective advance current knowledge surrounding social media effects peoples cognition affection health protective behaviors epidemics aim examine associations social media exposure covid19 risks related information preventive behavior public also role situation awareness crisis emotions including anxiety fear played methods online crosssectional survey conducted china total 632 participants recruited measures included exposure covid19 information social media situation awareness anxiety fear protective behaviors participants taken performed descriptive statistical analysis correlation mediation analysis test research hypotheses results findings indicated situation awareness positively associated social media use b 054 p amplt 0001 anxiety b 095 p amplt 0001 fear b 087 p amplt 0001 preventive behavior b 068 p amplt 0001 social media use would also indirect effect anxiety indirect effect 040 95 ci 034 046 fear indirect effect 035 95 ci 029 042 situation awareness serial mediation effect situation awareness fear correlation social media use preventive behavior testified indirect effect 004 95 ci 001 008 conclusions social media use might influence adoption preventive behaviors triggering situation awareness fear therefore health communication regarding covid19 prevention target people less internet access low ehealth literacy understanding positive role negative crisis emotions outbreaks could also help communicators policymakers develop appropriate strategies make people proactive avoid remaining health hazard
https://doi.org/10.1111/1467-9817.12081
Caroline Shulman|Tom Marshall|E. B. Dorman|Judith N. Bulmer|Felicity Cutts|Norbert Peshu|Kevin Marsh
Malaria in pregnancy: adverse effects on haemoglobin levels and birthweight in primigravidae and multigravidae
2,001
London School of Hygiene & Tropical Medicine|London School of Hygiene & Tropical Medicine|Homerton University Hospital|Royal Victoria Infirmary|London School of Hygiene & Tropical Medicine|Kenya Medical Research Institute|Kenya Medical Research Institute|University of Oxford
background areas endemic transmission malaria pregnancy associated severe maternal anaemia low birthweight babies prevalence infection highest primigravidae pg hence control efforts usually geared towards high risk group using sensitive measure placental infection investigated relationship activeacute activechronic past placental infection maternal anaemia low birthweight women gravidities methods january 1996 july 1997 912 women delivering kilifi district hospital kenya recruited haemoglobin peripheral malaria slides taken prior delivery placental biopsies smears taken time delivery birthweight maternal height weight measured soon birth information obtained socioeconomic educational status association placental malaria severe anaemia low birthweight investigated women different gravidities findings placental histology prevalence active past malaria gravidities high ranging 64 pg 30 gravidities 5 gravidities 14 active malaria infection associated severe maternal anaemia adjusted 221 95 ci 136 361 significant interaction chronic past malaria severe anaemia effects birthweight whereby risk low birthweight high women chronic past placental malaria severe anaemia 453 119 172 pg 135 457 40 gravidities 24 interpretation area moderate malaria transmission women parities substantially increased risk low birthweight severe anaemia result malaria infection pregnancy risk low birthweight likely particularly high areas high prevalence severe anaemia
https://doi.org/10.1371/journal.pone.0106579
April W. Armstrong|Ali Alikhan|Luyang Cheng|Clayton W. Schupp|C. Kurlinkus|Daniel B. Eisen
Portable video media for presenting informed consent and wound care instructions for skin biopsies: a randomized controlled trial
2,010
University of California, Davis|Mayo Clinic|Winneshiek Medical Center|University of California, Davis|University of California, Davis|University of California, Davis|University of California, Davis
background fastpaced dermatology clinics process obtaining informed consents biopsies providing postprocedure instructions may incomplete inconsistent objectives compare effectiveness videobased education verbal education giving informed consent providing postprocedure wound care instructions patients undergoing skin biopsies methods randomized controlled trial participants randomized receive either video education portable video devices conventional verbal instructions regarding skin biopsies participants completed skinbiopsy knowledge assessment patient satisfaction assessment evaluation educational medium main outcome measures differences changes prestudy poststudy knowledge assessment scores patient satisfaction evaluation educational medium results eightfour patients undergoing skin biopsies university california davis dermatology clinic participated study participants control group nonstatistically significant increase knowledge score mean sd 112 174 whereas video group statistically significant increase knowledge score mean sd 155 171 difference knowledge scores video verbal groups statistically significant participants groups highly satisfied biopsy education 10point scale mean sd usefulness appeal videos 901 15 901 166 respectively conclusions study demonstrated significant increase knowledge score following video education following oral education although betweengroup comparisons achieve statistical significance portable video media presenting informed consent wound care instructions skin biopsies appear effective result higher satisfaction traditional oral education
https://doi.org/10.1017/s0033291711002558
Adam Bennett|Samuel J. Smith|Sahr Yambasu|Amara Jambai|Wondimagegnehu Alemu|Augustin Kabano|Thomas P. Eisele
Household Possession and Use of Insecticide-Treated Mosquito Nets in Sierra Leone 6 Months after a National Mass-Distribution Campaign
2,012
Tulane University|Ministry of Health and Sanitation|Ministry of Health and Sanitation|Sierra Leone Urban Research Centre|Tulane University
background november 2010 sierra leone distributed three million longlasting insecticidetreated nets llins objective providing protection malaria individuals households country methods conducted nationally representative survey six months mass distribution campaign evaluate impact household insecticidetreated net itn ownership use examined factors associated household itn possession use logistic regression models results survey included 4620 households equal representation 14 districts six months campaign 876 households least one itn represents increase 137 recent estimate 37 2008 thirtysix percent households possess least one itn per two household members rural households likely urban households 12 itn household members difference socioeconomic status household head education among individuals households possessing 1 itn 765 slept itn night preceding survey individuals households household head heard malaria messaging correct knowledge malaria transmission least one itn hanging likely slept itn conclusions mass distribution campaign effective achieving high coverage levels across population notably among rural households malaria burden higher important gains equitable access malaria prevention need maintained produce longterm reductions malaria burden
https://doi.org/10.1192/bjp.185.4.342
Ahmed Waqas|Soo Huat Teoh|Luís Velez Lapão|Luíz Ary Messina|Jorge César Correia
Harnessing Telemedicine for the Provision of Health Care: Bibliometric and Scientometric Analysis
2,020
University of Liverpool|Universiti Sains Malaysia|Universidade Nova de Lisboa|National Education and Research Network|University of Geneva
background recent decades advances information technology given new momentum telemedicine research advances telemedicine range individual population levels allowing exchange patient information diagnosis management health problems primary care prevention education physicians via distance learning objective scientometric investigation aims examine collaborative research networks dominant research themes disciplines seminal research studies contributed field telemedicine information vital scientists institutions policy stakeholders evaluate research areas infrastructural scholarly contributions required methods analyses used citespace version 40 r5 drexel university javabased software allows scientometric analysis especially visualization collaborative networks research themes specific field results found scholarly activity experienced significant increase last decade important works conducted institutions located highincome countries disciplinespecific shift radiology telestroke teledermatology telepsychiatry primary care observed important innovations yielded collaborative influence reported following medical disciplines descending order public environmental occupational health psychiatry pediatrics health policy services nursing rehabilitation radiology pharmacology surgery respiratory medicine neurosciences obstetrics geriatrics conclusions despite continuous rise scholarly activity telemedicine noticed several gaps literature instance primary secondary research central telemedicine conducted context highincome countries including evidence synthesis approaches pertained implementation aspects telemedicine furthermore research landscape implementation telemedicine infrastructure expected see exponential progress covid19 era
https://doi.org/10.1111/jcpp.12790
Jennifer Isautier|Tessa Copp|Julie Ayre|Erin Cvejic|Gideon Meyerowitz-Katz|Carys Batcup|Carissa Bonner|Rachael H Dodd|Brooke Nickel|Kristen Pickles|Samuel Cornell|Thomas Dakin|Kirsten McCaffery
People’s Experiences and Satisfaction With Telehealth During the COVID-19 Pandemic in Australia: Cross-Sectional Survey Study
2,020
University of Sydney|University of Sydney|University of Sydney|University of Sydney|University of Wollongong|Sydney Local Health District|University of Sydney|University of Sydney|University of Sydney|University of Sydney|University of Sydney|University of Sydney|University of Sydney|University of Sydney
background response covid19 pandemic telehealth rapidly adopted deliver health care services around world date studies compared peoples experiences telehealth services pandemic australia experiences traditional inperson visits objective study aimed compare participants perceptions telehealth consults perceptions traditional inperson visits investigate whether people believe telehealth services would useful pandemic methods national crosssectional community survey conducted june 5 june 12 2020 australia total 1369 participants aged 18 years lived australia recruited via targeted advertisements social media ie facebook instagram participants responded survey questions telehealth experience included freetext response option generalized linear model used estimate adjusted relative risks poorer telehealth experience traditional inperson visit experience content analysis performed determine reasons telehealth experiences worse traditional inperson visit experiences results 596 telehealth users majority respondents n369 619 stated telehealth experience good better traditional inperson medical appointment experience average respondents perceived telehealth would moderately useful useful medical appointments covid19 pandemic ends mean 367 sd 11 male p007 history depression anxiety p016 lower patient activation scores ie individuals willingness take role managing healthhealth care p036 significantly associated poor telehealth experience total 6 overarching themes identified freetext responses participants telehealth experiences poorer traditional inperson medical appointment experiences follows communication effective limitations technology issues obtaining prescriptions pathology results reduced confidence doctor additional burden complex care inability physically examined conclusions based samples responses telehealth appointment experiences comparable traditional inperson medical appointment experiences telehealth may worthwhile mode health care delivery pandemic continues may continue worthwhile pandemic
https://doi.org/10.1097/der.0000000000000034
Young Hee Kim|Hyeonkyeong Lee|Young Sam Oh|Eunjeong Kang
RELIABILITY AND VALIDITY OF THE DEMENTIA HEALTH LITERACY SCALE: A PILOT STUDY
2,017
Kyung Hee University|University of Minnesota|Kyung Hee University|Korea Institute for Health and Social Affairs
background spite high prevalence dementia 919 south korea crcd 2017 little known dementia health literacy dhl among korean older adults current study aimed develop dhl scale culturally competent tailors korean older adults develop scale research adopted integrated model health literacy srensen et al 2012 theoretical framework four dimensions 1 access 2 understand 3 appraisal 4 apply methods data 2016 dementia literacy survey dls utilized probability sampling method dls 440 participants survey used final analysis study used exploratory factor analysis principalcomponents analysis confirmatory factor analysis evaluate factorial validity dhls apply dimension results exploratory factor analysis kmo bartletts test spherecity indicated dhl items factorable eigenvalue 298 extracted factor explained 745 variance four items cronbachs alpha 886 confirmatory factor analysis factor loadings statistically significant fit indices showed adequate fit data well conclusions findings indicated apply dimension showed good construct validity internal consistency results support idea apply dimension dhl scale adequately measures construct interest applying dementia health information seek use health care services dementia care settings
https://doi.org/10.1002/14651858.cd007459.pub2
Arica White|Djenaba Joseph|Sun Hee Rim|Christopher Johnson|Michel P Coleman|Claudia Allemani
Colon cancer survival in the United States by race and stage (2001?2009): Findings from the CONCORD?2 study
2,017
Centers for Disease Control and Prevention|Centers for Disease Control and Prevention|Centers for Disease Control and Prevention|London School of Hygiene & Tropical Medicine|London School of Hygiene & Tropical Medicine
background first concord study 2008 5year survival patients diagnosed colon cancer 1990 1994 united states among highest world 60 large racial disparities participating states concord2 study 2015 enabled examination survival trends 1995 2009 us states race stage methods authors analyzed data 37 state populationbased cancer registries covering approximately 80 us population patients diagnosed colon cancer 2001 2009 followed 2009 survival 5 years corrected background mortality net survival using statespecific racespecific life tables agestandardized using international cancer survival standard weights survival presented race black white stage state calendar period 20012003 20042009 account changes methods used collect stage results fiveyear net survival increased 09 637 2001 2003 646 2004 2009 black white patients diagnosed distantstage disease 2001 2003 215 vs 172 2004 2009 233 vs 188 survival improved blacks whites 5year net survival 910 lower blacks whites 2001 2003 547 vs 645 2004 2009 566 vs 654 absolute difference blacks whites decreased 1 decade conclusions fiveyear net survival colon cancer increased slightly time survival among blacks diagnosed 2004 2009 still reached level among whites diagnosed 1990 1994 15 20 years earlier findings suggest need targeted efforts improve screening ensure timely appropriate treatment especially blacks reduce large persistent disparity survival cancer 2017123501436 published 2017 article us government work public domain usa
https://doi.org/10.2196/28589
Mariano E. Menendez|Bastiaan T. van Hoorn|Michael Mackert|Erin E. Donovan|Neal C. Chen|David Ring
Patients With Limited Health Literacy Ask Fewer Questions During Office Visits With Hand Surgeons
2,017
Massachusetts General Hospital|Harvard University|Tufts Medical Center|Tufts University|Massachusetts General Hospital|Harvard University|The University of Texas at Austin|The University of Texas at Austin|Massachusetts General Hospital|Harvard University|Massachusetts General Hospital|Harvard University|The University of Texas at Austin
background midst rapid expansion medical knowledge decisionsupport tools intended benefit diverse patients patients limited health literacy ability obtain process understand information services make health decisions benefit asking questions engaging actively care little known regarding relationship health literacy questionasking behavior outpatient office visits questionspurposes 1 patients lower levels health literacy ask fewer questions general stratified types questions 2 patient characteristics associated number questions asked 3 often surgeons prompt patients ask questions office visit methods audiorecorded office visits 84 patients visiting one three orthopaedic hand surgeons first time patient questions counted coded using adaptation roter interaction analysis system 11 categories 1 therapeutic regimen 2 medical condition 3 lifestyle 4 requests services medications 5 psychosocialfeelings 6 nonmedicalprocedural 7 asks understanding 8 asks reassurance 9 paraphrasechecks understanding 10 bid repetition 11 personal remarkssocial conversation directly visit patients completed newest vital sign nvs health literacy test sociodemographic survey including age sex race work status marital status insurance status three patientreported outcomes measurement information systembased questionnaires upperextremity function pain interference depression nvs scores divided limited 03 adequate 46 health literacy done tools creators also assessed whether surgeons prompted patients ask questions encounter results patients limited health literacy asked fewer questions patients adequate health literacy 5 4 versus 9 7 mean difference 4 95 ci 7 1 p 0002 specifically patients limited health literacy asked fewer questions regarding medicalcare issues therapeutic regimen 1 2 versus 3 4 mean difference 2 95 ci 4 1 p 0001 condition 2 2 versus 3 3 mean difference 1 95 ci 3 0 p 0022 nonwhite patients asked fewer questions white patients 5 4 versus 9 7 mean difference 4 95 ci 7 0 p 0032 patient characteristics associated number questions asked surgeons occasionally 29 2484 asked patients questions encounter patients 79 1924 asked questions conclusions limited health literacy barrier effective patient engagement hand surgery care increasingly tangled healthinformation environment important actively involve patients limited health literacy decisionmaking process encouraging questionasking particularly practice settings decisions preferencesensitive instead assuming patients understand told orthopaedic surgeons may take universal precautions assuming patients understand unless proved otherwise level evidence level ii therapeutic study
https://doi.org/10.2196/17163
Miaomiao Tian|Da Feng|Xi Chen|Ying?Chun Chen|Xi Sun|Yuanxi Xiang|Yuan Fang|Zhanchun Feng
China's Rural Public Health System Performance: A Cross-Sectional Study
2,013
Huazhong University of Science and Technology|Chinese Academy of Medical Sciences & Peking Union Medical College|Huazhong University of Science and Technology|Jiangsu University|Huazhong University of Science and Technology|Huazhong University of Science and Technology|Huazhong University of Science and Technology|Huazhong University of Science and Technology|Huazhong University of Science and Technology|Huazhong University of Science and Technology
background past three years government china initiated health reform rural public health system construction achieve equal access public health services rural residents study assessed trends public health services accessibility rural china 2008 2010 well current situation chinas rural public health system performance methods data collected crosssectional survey conducted 2011 used multistage stratified random sampling method select 12 counties 118 villages china three sets indicators chosen measure trends access coverage equality effectiveness rural public health services data disaggregated provinces participants hypertension patients children elderly women examined changes equality across within region results chinas rural public health system well safe drinking water children vaccinations women hospital delivery hypertension patients low income could receive regular healthcare primary health institutions middle high income 2010 hypertension treatment rate qinghai western china 5322 much lower zhejiang eastern china 9727 meanwhile low performance showed effectiveness rural public health services rate effective treatment controlling blood pressure within normal range 397 conclusions implementation health reform since 2009 led public health development towards right direction physical access public health services increased 2008 2010 inter intraregional inequalities public health system coverage still exist strategies improve quality equality public health services rural china need considered
https://doi.org/10.1371/journal.pmed.1003409
Gill Livingston|Gerard Leavey|G. Kitchen|Mônica Manela|Sati Sembhi|Cornelius Katona
Mental health of migrant elders – the Islington study
2,001
University College London|The Royal Free Hospital|Camden and Islington NHS Foundation Trust|University College London|The Royal Free Hospital|Camden and Islington NHS Foundation Trust|University College London|The Royal Free Hospital
background uk 6 aged 65 years born abroad live innercity areas suggested ethnic elders particularly vulnerable mental illness aims compare prevalence dementia depression older migrants born uk method crosssectional community study 1085 people aged 65 years older innerlondon borough results compared born uk prevalence dementia raised africancaribbeans 173 relative risk172 cl106281 lower irishborn 36 relative risk036 cl017087 africancaribbean country birth significantly younger p 0000 likely taking antihypertensive drugs likely report cardiovascular problems increased rates diabetes p lt 00000 overall prevalence depression 183 95 cl161207 highest prevalence rate found among born greece turkey 272 cl179396 migration per se appear risk depression dementia population conclusions excess dementia may vascular aetiology potential primary secondary prevention
https://doi.org/10.1016/s0140-6736(15)60123-4
Deborah Cohan|E. Gómez|Mara Greenberg|Sierra Washington|Edwin D. Charlebois
Patient Perspectives with Abbreviated versus Standard Pre-Test HIV Counseling in the Prenatal Setting: A Randomized-Controlled, Non-Inferiority Trial
2,009
University of California, San Francisco|University of California, San Francisco|Stanford University|University of California, San Francisco|University of California, San Francisco
background us unacceptably high percentage pregnant women undergo prenatal hiv testing previous studies found increased uptake prenatal hiv testing abbreviated pretest counseling however little known patient decision making testing satisfaction knowledge setting methodologyfindings randomizedcontrolled noninferiority trial conducted october 2006 february 2008 san francisco general hospital sfgh public teaching hospital city county san francisco total 278 english spanishspeaking pregnant women randomized receive either abbreviated standard nurseperformed hiv test counseling initial prenatal visit patient decision making experience compared abbreviated versus standard hiv counseling strategies among sample lowincome urban ethnically diverse prenatal patients primary outcome decisional conflict score dcs using oconnor lowliteracy scale secondary outcomes included satisfaction test decision basic hiv knowledge hiv testing uptake conducted intentiontotreat analysis 278 women 134 482 abbreviated arm aa 144 518 standard arm sa significant difference proportion women low decisional conflict 716 aa vs 764 sa p 37 observed mean difference groups 388 95 ci 065 841 exceed noninferiority margin hiv testing uptake high 97 8 differ significantly 2 groups 993 aa vs 965 sa p 12 likewise difference satisfaction testing decision 978 aa vs 993 sa p 36 however women aa significantly lower mean hiv knowledge scores 784 compared women sa 837 p001 conclusionssignificance study suggests streamlining pretest counseling process associated slightly lower knowledge compromise patient decision making satisfaction regarding hiv testing trial registration clinicaltrialsgov nct00503308
https://doi.org/10.1192/bjp.bp.113.128470
Guendalina Graffigna|Serena Barello|Andrea Bonanomi
The role of Patient Health Engagement Model (PHE-model) in affecting patient activation and medication adherence: A structural equation model
2,017
Università Cattolica del Sacro Cuore|Università Cattolica del Sacro Cuore|Università Cattolica del Sacro Cuore
background increasing bodies scientific research today examines factors interventions affecting patients ability selfmanage adhere treatment patient activation considered reliable indicator patients ability manage health autonomously studies tried assess role psychosocial factors promoting patient activation systematic modeling psychosocial factors explaining variance patient activation needed objective test hypothesized effect patient activation medication adherence test hypothesized effects positive emotions quality patientdoctor relationship patient activation test hypothesized mediating effect patient health engagement phemodel pathway material methods crosssectional study involved 352 italianspeaking adult chronic patients survey included measures patient activation patient activation measure 13 short form ii patient health engagement model patient health engagement scale iii patient adherence 4 itemmorinsky medication adherence scale iv quality patients emotional feelings manikin self assessment scale v quality patientdoctor relationship health care climate questionnaire structural equation modeling used test hypotheses proposed results according theoretical model hypothesized research results confirmed patients activation significantly affects reported medication adherence moreover psychosocial factors patients quality emotional feelings quality patientdoctor relationship demonstrated factors affecting level patient activation finally mediation effect patient health engagement model confirmed analysis conclusions consistently results previous studies findings demonstrate patient health engagement model critical factor enhancing quality care patient health engagement model might acts mechanism increase patient activation adherence
https://doi.org/10.1002/14651858.cd009149.pub2
Chunling Lu|Jorge Cuartas|Günther Fink|Dana Charles McCoy|Kai Liu|Zhihui Li|Bernadette Daelmans|Linda Richter
Inequalities in early childhood care and development in low/middle-income countries: 2010–2018
2,020
Brigham and Women's Hospital|Harvard University|Harvard University|Swiss Tropical and Public Health Institute|University of Basel|Harvard University|Renmin University of China|Harvard Global Health Institute|Harvard University|World Health Organization|University of the Witwatersrand
background inequalities early childhood development ecd tend persist adulthood amplify across life course date little research inequalities early childhood care development lowmiddleincome countries available guide governments donors civil society identifying young children families targeted policies programmes improve nurturing care could prevent left behind methods using data 135 demographic health surveys multiple indicator cluster surveys 2010 2018 assessed levels trends inequalities exposure risks stunting extreme poverty age 5 levels 85 trends 40 countries early attendance early care education programmes 3659 months 65 17 countries home stimulation 3659 months 62 14 countries child development according early childhood development index 3659 months 60 13 countries inequalities within countries measured absolute gap three domainschild gender household wealth residential areaand compared across regions country income groups results 63 children exposed stunting extreme poverty 39 34year olds attended early care education 69 received level reported home stimulation defined adequate subsaharan africa lowest proportion children exposed stunting extreme poverty 45 attending early care education 24 receiving adequate home stimulation 47 substantial gaps indicators found across country income groups residential areas household wealth categories significant reductions gaps time subset countries available data two survey rounds conclusions available data indicate large inequalities early experiences outcomes efforts reducing inequalities must focus poorest families living rural areas poorest countries improving applying populationlevel measurements ecd countries time important ensuring equal opportunities young children globally
https://doi.org/10.1016/j.hrtlng.2019.05.011
Martin Wiesner|Richard Zowalla|Monika Pobiruchin
The Difficulty of German Information Booklets on Psoriasis and Psoriatic Arthritis: Automated Readability and Vocabulary Analysis
2,020
Heilbronn University|German Medical Association|Heilbronn University|German Medical Association|Heilbronn University
background informationseeking psoriasis psoriatic arthritis patients confronted numerous educational materials looking internet literature suggests 170214 psoriasis psoriatic arthritis patients good level knowledge psoriasis treatment selfmanagement study 1994 found english psoriasispsoriatic arthritis brochures required reading level grades 812 understandable confirmed followup study 20 years later readability written healthrelated text material exceed sixthgrade level psoriasispsoriatic arthritis material seems illsuited target audience however data available readability levels psoriasispsoriatic arthritis brochures germanspeaking patients volume scope unclear objective study aimed analyze freely available educational materials psoriasispsoriatic arthritis patients written german quantifying difficulty assessing readability vocabulary used collected brochures methods data collection conducted manually via internet search engine psoriasispsoriatic arthritisspecific material published pdf documents next raw text extracted computerbased readability vocabulary analysis performed brochure readability analysis applied flesch reading ease fre metric adapted german language fourth vienna formula wstf assess laymenfriendliness vocabulary computation expert level conducted using specifically trained support vector machine classifier twosided twosample wilcoxon test applied test whether difficulty brochures pairwise topic groups different results total n68 brochures included readability assessment 71 4868 published pharmaceutical companies 22 1568 nonprofit organizations 7 568 public institutions collection separated four topic groups basic information psoriasispsoriatic arthritis g1g2 lifestyle behavior psoriasispsoriatic arthritis g3g4 medication therapy guidance g5 topics g6 average readability levels comparatively low fre3158 wstf1184 however twothirds educational materials 69 4768 achieved vocabulary score 4 ie easy easy therefore suitable lay audience statistically significant differences brochure groups g1 g3 fre p001 wstf p003 vocabulary measure l p01 exist statistically significant differences g2 g4 terms fre p03 wstf p03 l p03 conclusions online psoriasispsoriatic arthritis patient education materials german require average college university education level result patients face barriers understanding available material even though vocabulary used seems appropriate reason publishers psoriasispsoriatic arthritis brochures carefully revise educational materials provide easier comprehensible information patients lower health literacy levels
https://doi.org/10.1371/journal.pone.0213593
Shlomo A. Koyfman|C.A. Reddy|Sabahat Hizlan|Angela C. Leek|and Eric D. Kodish
Informed consent conversations and documents: A quantitative comparison
2,015
Cleveland Clinic|Cleveland Clinic|Cleveland Clinic|Cleveland Clinic|Cleveland Clinic
background informed consent clinical research includes 2 components informed consent documents icds informed consent conversations iccs readability software used help simplify language icd authors knowledge rarely used assess language used icc may influence quality informed consent current analysis performed determine whether length reading levels transcribed iccs lower corresponding icds selected clinical trials assess whether investigator experience affected use simpler language comprehensiveness methods current study prospective study iccs audiorecorded 6 institutions families offered participation pediatric phase oncology trials word count fleschkincaid grade level fkgl flesch reading ease score fres iccs compared corresponding icds including frequency investigators addressed 8 prespecified critical consent elements icc results sixtynine unique physicianprotocol pairs identified overall iccs contained fewer words 4677 vs 6364 words p 0016 lower fkgl 6 vs 97 p 0001 higher fres 778 vs 567 p lt0001 compared respective icds likely omit critical consent elements voluntariness 55 doselimiting toxicities 26 years investigator experience correlated reliably covering critical elements decreased linguistic complexity conclusions clinicians use understandable language iccs corresponding icd appear less reliably cover elements critical fully informed consent efforts focused providing communication training clinicianinvestigators made optimize synergy icd icc cancer 2016122464469 2015 american cancer society
https://doi.org/10.1111/j.1475-3588.2012.00673.x
Farah Ahmad|Christo El Morr|Paul Ritvo|Nasih Othman|Rahim Moineddin|Mvc Team
An Eight-Week, Web-Based Mindfulness Virtual Community Intervention for Students’ Mental Health: Randomized Controlled Trial
2,020
York University|York University|York University|York University|Public Health Ontario|University of Toronto
background innovative interventions needed address increasing mental health needs university students given demonstrated anxiolytic antidepressant benefits mindfulness training developed 8week webbased mindfulness virtual community mvc intervention informed cognitive behavioral therapy cbt constructs objective study investigated efficacy mvc intervention reducing symptoms depression anxiety stress among undergraduate students toronto canada secondary outcomes included quality life life satisfaction mindfulness methods first 4 weeks full mvc intervention fmvc comprised 1 12 videobased modules psychoeducation students preidentified stressful topics topically applied mindfulness practice 2 anonymous peertopeer discussion forums 3 anonymous groupbased professionally guided 20min live videoconferences second 4 weeks fmvc involved access videobased modules 8week partial mvc pmvc comprised 12 videobased modules randomized controlled trial conducted 4 parallel arms fmvc pmvc waitlist control wlc groupbased facetoface cbt results latter group presented elsewhere students recruited multiple strategies consented randomized wlc40 fmvc40 pmvc39 learned allocation consenting online surveys baseline t1 4 weeks t2 8 weeks t3 included patient health questionnaire9 item beck anxiety inventory perceived stress scale quality life scale brief multidimensional students life satisfaction scale fivefacet mindfulness questionnaire analyses employed generalized estimation equation methods ar1 covariance structures adjusted possible confounders gender age birth country paid work unpaid work physical activities selfrated health mental health counseling access results 113 students provided t1 data 28 males 85 females mean age 248 years participants fmvc n39 pmvc n35 wlc n39 groups similar sociodemographic characteristics t1 t3 followup per adjusted comparisons statistically significant reductions depression scores fmvc score change 403 plt001 pmvc score change 482 plt001 compared wlc t3 statistically significant reduction anxiety scores pmvc score change 735 p01 compared wlc statistically significant reduction scores perceived stress fmvc score change 532 plt001 pmvc score change 561 p005 compared wlc statistically significant changes t3 quality life mindfulness fmvc pmvc vs wlc life satisfaction conclusions internetbased mindfulness cbtbased interventions fmvc pmvc result significant reductions symptoms depression anxiety stress student population future research larger sample multiple universities would precisely test generalizability trial registration international standard randomized controlled trial number isrctn92827275 httpswwwisrctncomisrctn92827275
https://doi.org/10.1371/journal.pone.0187861
Olaf Müller|Manuela De Allegri|Heiko Becher|Justin Tiendrebogo|Claudia Beiersmann|Maurice Yé|Bocar Kouyaté|Ali Sié|Albrecht Jahn
Distribution Systems of Insecticide-Treated Bed Nets for Malaria Control in Rural Burkina Faso: Cluster-Randomized Controlled Trial
2,008
Heidelberg University|Heidelberg University|Heidelberg University|Centre de Recherche en Santé de Nouna|Heidelberg University|Centre de Recherche en Santé de Nouna|Centre National de Recherche et de Formation sur le Paludisme|Centre de Recherche en Santé de Nouna|Heidelberg University
background insecticideimpregnated bed nets itns shown highly effective tool malaria endemic regions subsaharan africa ssa however different opinions role itn social marketing itn free distribution rollout itn programmes objective study evaluate effects free itn distribution antenatal care services addition itn social marketing programme area typical rural ssa methods clusterrandomised controlled itn trial took place whole kossi province northwestern burkina faso area highly endemic malaria twelve clusters assigned longterm itn serena brand social marketing plus free itn serena brand distribution pregnant women attending governmental antenatal care services group 13 clusters itn social marketing group b intervention took place rainy season 2006 thereafter trial evaluated representative household survey baseline one year serena itn household ownership primary outcome measure findings total 1052 households visited baseline february 2006 1050 followup february 2007 overall serena itn household ownership increased 16 28 study period significantly higher increase group 13 35 group b 18 23 p0001 interpretation free distribution itns pregnant women governmental antenatal care services addition itn social marketing substantially improved itn household ownership rural burkina faso trial registration controlledtrialscom isrctn07985309
https://doi.org/10.2196/15779
Peter Schulz|Annalisa Pessina|Uwe Hartung|Serena Petrocchi
Effects of Objective and Subjective Health Literacy on Patients’ Accurate Judgment of Health Information and Decision-Making Ability: Survey Study
2,021
Università della Svizzera italiana|Università della Svizzera italiana|Università della Svizzera italiana|Università della Svizzera italiana
background interpreting health information acquiring health knowledge become important accumulation scientific medical knowledge ideals patient autonomy health literacy tremendous success concept considered admission well distribution health knowledge internet makes health information much easily accessible ever introduces problems health disinformation major one objective objective study determine whether objective subjective health literacy independent concepts test two associated strongly accurate judgments quality medical website behavioral intentions beneficial health methods survey depression treatments conducted online n362 newest vital sign employed measure objective performancebased health literacy ehealth literacy scale used measure subjective perceptionbased health literacy correlations comparisons means linear binary logistic regression mediation models used determine associations results objective subjective health literacy weakly associated one another r006 p24 high objective health literacy levels associated inclination behave ways beneficial ones others health expb2068 p004 ability recognize lowquality online sources health information 4698 p005 recognition also improved participants choice treatment 3345 plt001 objective health literacy helped people recognize misinformation health websites improved judgment treatment depression conclusions selfreported perceptionbased health literacy treated separate concept objective performancebased health literacy objective health literacy appears potential prevent people becoming victims health disinformation
https://doi.org/10.1371/journal.pone.0203353
Shannon M. Christy|Stacy N. Davis|Kimberly Williams|Xiuhua Zhao|Swapomthi Govindaraju|Gwendolyn P. Quinn|Susan T. Vadaparampil|Hui?Yi Lin|Steven K. Sutton|Richard R. Roethzeim|David Shibata|Cathy D. Meade|Clement K. Gwede
A community-based trial of educational interventions with fecal immunochemical tests for colorectal cancer screening uptake among blacks in community settings
2,016
Moffitt Cancer Center|University of South Florida|Moffitt Cancer Center|Moffitt Cancer Center|Moffitt Cancer Center|Moffitt Cancer Center|University of South Florida|Moffitt Cancer Center|Moffitt Cancer Center|Moffitt Cancer Center|Louisiana State University Health Sciences Center New Orleans|University of South Florida|Moffitt Cancer Center|University of South Florida|Moffitt Cancer Center|Moffitt Cancer Center|University of South Florida|University of Tennessee Health Science Center|Moffitt Cancer Center|University of South Florida|Moffitt Cancer Center|University of South Florida
background intervention studies among individuals diverse community settings needed reduce health disparities colorectal cancer crc screening mortality rates current study compared efficacy 2 intervention conditions promoting crc screening among black individuals methods black individuals ages 50 75 years n 330 recruited community settings 4 tampa bay counties obtaining consent conducting baseline interview assess sociodemographic healthrelated variables participants received either culturally targeted crc photonovella booklet plus fecal immunochemical test fit kit standard crc screening brochure plus fit kit primary outcome fit kit screening uptake results fit screening uptake 6 months 867 overall 903 brochure group 819 photonovella group controlling baseline betweengroup differences influence intervention fit kit uptake p 756 significant predictors returning fit kit included unable work p 010 higher religious belief scores p 015 living farther cancer center p 015 conclusions providing fit kits educational print materials black individuals community settings resulted high rates crc screening study also identified subgroups participants less likely return fit kit provides insight future interventions cancer 201612232883296 2016 american cancer society
https://doi.org/10.2196/19661
Kayoko Yoshikawa|T.M. Shakya|Krishna C. Poudel|Masamine Jimba
Acceptance of Wife Beating and Its Association with Physical Violence towards Women in Nepal: A Cross-Sectional Study Using Couple’s Data
2,014
The University of Tokyo|University of Massachusetts Amherst|The University of Tokyo
background intimate partner violence ipv serious global public health issue acceptance wife beating known associated ipv studies analysed acceptance wife beating women mens points view objective study examine whether acceptance wife beating among couples associated lifetime past oneyear physical ipv perpetration towards wives nepal methods crosssectional study conducted august september 2011 717 randomly selected couples wives aged 18 49 years old kirtipur municipality bhaktapur district nepal wives husbands acceptance wife beating measured six scale items physical ipv experience among wives measured seven physical assault scale items assess association acceptance wife beating physical ipv multiple logistic regression analysis used results nearly 30 wives husbands indicated beating wives acceptable certain circumstances statistically significant difference detected wives husbands level acceptance wife beating however husbands acceptance wife beating positively associated lifetime past oneyear perpetration physical ipv whereas wives acceptance wife beating neither associated lifetime past oneyear victimization physical ipv positive association husbands remained even controlling partners factors conclusions acceptance wife beating important risk factor must considered prevent perpetration physical ipv towards wives nepal future studies include men better understand structure dynamics ipv nepal prevention programs also target men change attitudes identify couples risk physical ipv occurring toward wives
https://doi.org/10.1177/2047487317750913
Nicole Ketelaar|Marjan J. Faber|Signe Flottorp|Liv Helen Rygh|Katherine Deane|Martin Eccles
Public release of performance data in changing the behaviour of healthcare consumers, professionals or organisations
2,011
Radboud University Nijmegen|Radboud University Medical Center|Radboud University Nijmegen|Radboud University Medical Center|Nasjonalt Kunnskapssenter for Helsetjenesten|University of Bergen|Nasjonalt Kunnskapssenter for Helsetjenesten|University of East Anglia|Newcastle University
background becoming increasingly common release information performance hospitals health professionals providers healthcare organisations public domain however know information used extent reporting leads quality improvement changing behaviour healthcare consumers providers purchasers extent performance professionals providers affected objectives determine effectiveness public release performance data changing behaviour healthcare consumers professionals organisations search methods searched cochrane central register controlled trials central cochrane effective practice organisation care epoc trials register medline ovid 1966 embase ovid 1979 cinahl psycinfo ovid 1806 dare 2011 selection criteria searched randomised quasirandomised trials interrupted time series controlled beforeafter studies effects publicly releasing data regarding aspect performance healthcare organisations individuals papers report least one main outcome related selecting changing care outcome measures awareness attitude views knowledge performance data costs data collection analysis two review authors independently screened studies eligibility extracted data study extracted data target groups healthcare consumers healthcare providers healthcare purchasers performance data main outcomes choice healthcare provider improvement means changes care outcomes awareness attitude views knowledge performance data costs main results included four studies containing 35000 consumers 1560 hospitals three studies conducted usa examined consumer behaviour public release performance data two studies found effect consumer assessment healthcare providers systems information health plan choice medicaid population one interrupted time series study found small positive effect publishing data patient volumes coronary bypass surgery lowcomplication outliers lumbar discectomy effects persist longer two months public release effects patient volumes acute myocardial infarction found one clusterrandomised controlled trial conducted canada studied improvement changes care public release performance data patients acute myocardial infarction congestive heart failure effects composite processofcare indicators either condition found improvements individual processofcare indicators effect mortality rates acute myocardial infarction quality improvement activities initiated response publiclyreleased report cards secondary outcomes reported authors conclusions small body evidence available provides consistent evidence public release performance data changes consumer behaviour improves care evidence public release performance data may impact behaviour healthcare professionals organisations lacking
https://doi.org/10.1016/j.whi.2006.09.002
Rufus Akinyemi|Fred Stephen Sarfo|Joshua Akinyemi|Arti Singh|Matthew Onoja Akpa|Albert Akpalu|Lukman Owolabi|Abiodun M. Adeoye|Reginald Obiako|Kolawole Wahab|Emmanuel Sanya|Morenikeji Komolafe|Godwin Ogbole|Bimbo Fawale|Philip Adebayo|Godwin Osaigbovo|Taofiki Sunmonu|Paul Olowoyo|Innocent Ijezie Chukwuonye|Yahaya Obiabo|Olaleye Adeniji|Gregory Fakunle|Ezinne Sylvia Melikam|Raelle Saulson|Joseph Yaria|Kelechi Uwanruochi|Phillip Oluleke Ibinaiye|Ganiyu Amusa|Isah Suleiman Yahaya|Abdullahi Hamisu Dambatta|Mercy Faniyan|Peter Olowoniyi|Andrew Bock-Oruma|Odo Chidi Joseph|Ayodipupo Sikiru Oguntade|P.M. Kolo|Ruth Laryea|Sulaiman Lakoh|Ezinne Uvere|Temitope Farombi|Josephine Akpalu|Olalekan Oyinloye|Lambert Appiah|Benedict Calys?Tagoe|Vincent Shidali|Nasir Abdulkadir Tabari|Oladimeji Adebayo|Richard Efidi|Osi Adeleye|Dorcas Owusu|Luqman Ogunjimi|Olumayowa Aridegbe|Chidiebere Lucius Imoh|Taofeeq Sanni|Mulugeta Gebreziabher|Hemant K. Tiwari|Oyedunni Arulogun|Adesola Ogunniyi|Carolyn Jenkins|Mayowa Owolabi|Bruce Ovbiagele
Knowledge, attitudes and practices of West Africans on genetic studies of stroke: Evidence from the SIREN Study
2,018
University of Ibadan|Federal Medical Centre|Kwame Nkrumah University of Science and Technology|University of Ibadan|Kwame Nkrumah University of Science and Technology|University of Ibadan|University of Ghana|Bayero University Kano|Aminu Kano Teaching Hospital|University of Ibadan|Ahmadu Bello University Teaching Hospital|University of Ilorin Teaching Hospital|University of Ilorin Teaching Hospital|Obafemi Awolowo University|University of Ibadan|Obafemi Awolowo University|Ladoke Akintola University of Technology|Jos University Teaching Hospital|Federal Medical Centre|Federal Medical Centre|Delta State University|Federal Medical Centre|University of Ibadan|University of Ibadan|Medical University of South Carolina|University College Hospital, Ibadan|Federal Medical Centre|Ahmadu Bello University Teaching Hospital|Jos University Teaching Hospital|Bayero University Kano|Aminu Kano Teaching Hospital|Bayero University Kano|Aminu Kano Teaching Hospital|University of Ibadan|Federal Medical Centre|Delta State University|University College Hospital, Ibadan|University College Hospital, Ibadan|University of Ilorin Teaching Hospital|University of Ghana|University College Hospital, Ibadan|University of Ibadan|University College Hospital, Ibadan|University of Ghana|University of Ilorin Teaching Hospital|Kwame Nkrumah University of Science and Technology|University of Ghana|Ahmadu Bello University Teaching Hospital|Bayero University Kano|Aminu Kano Teaching Hospital|University College Hospital, Ibadan|University College Hospital, Ibadan|Federal Medical Centre|Kwame Nkrumah University of Science and Technology|University College Hospital, Ibadan|Federal Medical Centre|Jos University Teaching Hospital|Medical University of South Carolina|University of Alabama at Birmingham|University of Ibadan|University of Ibadan|Medical University of South Carolina|University of Ibadan|Medical University of South Carolina
background crucial assess genomic literacy related stroke among africans preparation ethical legal societal implications genetic revolution begun africa objective assess knowledge attitudes practices kap west africans stroke genetic studies methods comparative crosssectional study conducted among stroke patients strokefree controls recruited across 15 sites ghana nigeria participants knowledge heritability stroke willingness undergo genetic testing perception potential benefits stroke genetic research assessed using intervieweradministered questionnaire descriptive frequency distribution multiple regression analyses performed results 49 2029 stroke patients 57 2603 strokefree individuals knew stroke heritable disorder among knew 90 willing undergo genetic testing knowledge stroke heritability associated least postsecondary education 151 125181 family history stroke 120 103139 islamic religion or082 ci 072094 currently unmarried 081 ci 070092 alcohol use 078 ci 067091 associated lower odds awareness stroke heritable disorder willingness undergo genetic testing stroke associated family history stroke 134 103174 inversely associated medical history high blood pressure 079 065096 conclusion improve knowledge stroke heritability willingness embrace genetic testing stroke individuals less formal education history high blood pressure family history stroke require targeted interventions
https://doi.org/10.1192/bjp.bp.114.151944
B. Saravanan|KS Jacob|Shanthi Johnson|Martin Prince|Dinesh Bhugra|Anthony S. David
Assessing insight in schizophrenia: East meets West
2,007
Christian Medical College & Hospital|Christian Medical College & Hospital|Christian Medical College & Hospital|King's College London|King's College London|King's College London
background lack insight observed people schizophrenia across cultures assessment insight must take account prevailing illness models aims determine whether culturally specific western biomedical interpretations insight psychosis reconciled method patients schizophrenia n 131 assessed first contact psychiatric services vellore south india patients explanatory models psychopathology insight investigated using standard schedule translated tamil results supernatural explanations symptoms frequent insight dimensions weakly associated inversely severity symptoms whereas preserved insight associated anxiety helpseeking perception change willingness attribute symptoms disease others ones self supernatural forces strongly associated insight conclusions relationship insight awareness illness clinical variables similar south india elsewhere however assessment insight might failed capture locally accepted explanatory frameworks inclusive conceptual model emphasises helpseeking recommended
https://doi.org/10.1161/circoutcomes.114.001223
Meihua Piao|Hyeongju Ryu|Hyeongsuk Lee|Jeongeun Kim
Use of the Healthy Lifestyle Coaching Chatbot App to Promote Stair-Climbing Habits Among Office Workers: Exploratory Randomized Controlled Trial
2,020
Seoul National University Hospital|Seoul National University|Gachon University|Seoul National University
background lack time exercise common among office workers given busy lives occupational restrictions difficulty taking time necessary suggest effective ways workers exercise regularly sustaining lifestyle habits increase nonexercise activity daily life solve issue lack exercise time healthy lifestyle coaching chatbot messenger app based habit formation model used tool provide health behavior intervention emphasizes importance sustainability involvement objective study aimed assess efficacy healthy lifestyle coaching chatbot intervention presented via messenger app aimed stairclimbing habit formation office workers methods february 1 2018 april 30 2018 total 106 people participated trial online recruitment participants randomly assigned intervention group n57 control group n49 intervention group received cues intrinsic extrinsic rewards entire 12 weeks however control group receive intrinsic rewards first 4 weeks received rewards intervention group fifth twelfth week selfreport habit index srhi participants evaluated every week level physical activity measured beginning end trial spss statistics version 21 ibm corp used statistical analysis results 4 weeks intervention without providing intrinsic rewards control group change srhi scores 1354 sd 1499 intervention group 642 sd 942 control group indicating significant difference groups p04 rewards given groups fifth twelfth week change srhi scores intervention control groups comparable 1208 sd 1087 1588 sd 1329 respectively p21 however level physical activity showed significant difference groups 12 weeks intervention p045 conclusions study provides evidence intrinsic rewards important enhance sustainability effectiveness intervention healthy lifestyle coaching chatbot program costeffective method healthy habit formation trial registration clinical research information service kct0004009 httpstinyurlcomw4oo7md
https://doi.org/10.1192/bjp.bp.115.177139
Courtenay Norbury|George Vamvakas|Debbie Gooch|Gillian Baird|Tony Charman|Emily Simonoff|Andrew Pickles
Language growth in children with heterogeneous language disorders: a population study
2,017
University College London|Royal Holloway University of London|King's College London|University College London|Royal Holloway University of London|Guy's and St Thomas' NHS Foundation Trust|King's College London|King's College London|King's College London
background language development characterised significant individual stability school entry however extent trajectories language growth vary children language disorder function cooccurring developmental challenges question theoretical import implications service provision methods scales employed populationbased survey design sample weighting procedures estimate growth core language skills first three years school stratified sample n 529 received comprehensive assessment language nonverbal iq social emotional behavioural difficulties 56 years age 95 sample n 499 assessed ages 78 language growth measured using raw standard scores children typical development children language disorder unknown origin children language disorders associated known clinical condition andor intellectual disability results overall language stable individual level estimated icc 095 first three years school linear mixed effects models highlighted steady growth language raw scores across three groups including multiple developmental challenges little evidence however children language disorders narrowing gap peers z scores adjusted models indicated nonverbal ability socioeconomic status social emotional behavioural deficits predicted initial language score intercept none predicted language growth slope conclusions findings corroborate previous studies suggesting stable language trajectories ages 56 years add considerably previous work demonstrating similar developmental patterns children additional nonverbal cognitive deficits social emotional behavioural challenges social disadvantage clinical diagnoses
https://doi.org/10.1016/j.jand.2017.10.014
Andrew Pickles|Kevin Durkin|Pearl L. H. Mok|Umar Toseeb|Gina Conti?Ramsden
Conduct problems co-occur with hyperactivity in children with language impairment: A longitudinal study from childhood to adolescence
2,016
King's College London|University of Strathclyde|University of Manchester|University of Manchester|University of Manchester
background language impairment common developmental disorder frequently associated externalising problems study investigate first time joint trajectories conduct problems hyperactivity children language impairment childhood adolescence determine patterns cooccurrence symptoms identify specific risk protective factors methods develop trajectory grouping method examine simultaneously conduct hyperactivity problem scores 164 children language impairment 7 8 11 16 years age results identified five groups children distinct trajectories symptoms three trajectory groups different conducthyperactivity problems persistent problems group 15 adolescentonset group 24 childhoodlimited group 17 two trajectory groups show conduct problems conclusions conduct problems always cooccurred hyperactivity children language impairment regardless differences onset symptoms childhood versus adolescence persistence persistent versus childhood limited reading difficulties strongly associated mixed conducthyperactivity problems started early childhood continued adolescence persistent trajectory group prosocial behaviours found protective conduct problems
https://doi.org/10.1161/jaha.119.012277
Dimitrios-Alexios Karagiannis-Voules|Ronaldo Guilherme Carvalho Scholte|Luiz Henrique Guimarães|Jürg Utzinger|Penelope Vounatsou
Bayesian Geostatistical Modeling of Leishmaniasis Incidence in Brazil
2,013
University of Basel|Swiss Tropical and Public Health Institute|University of Basel|Swiss Tropical and Public Health Institute|Fundação Oswaldo Cruz|Complexo Hospitalar Universitário Professor Edgard Santos|Universidade Federal da Bahia|University of Basel|Swiss Tropical and Public Health Institute|University of Basel|Swiss Tropical and Public Health Institute
background leishmaniasis endemic 98 countries estimated 350 million people risk approximately 2 million cases annually brazil one severely affected countries methodology applied bayesian geostatistical negative binomial models analyze reported incidence data cutaneous visceral leishmaniasis brazil covering 10year period 20012010 particular emphasis placed spatial temporal patterns models fitted using integrated nested laplace approximations perform fast approximate bayesian inference bayesian variable selection employed determine important climatic environmental socioeconomic predictors cutaneous visceral leishmaniasis principal findings types leishmaniasis precipitation socioeconomic proxies identified important risk factors predicted number cases 2010 30189 standard deviation sd 7676 cutaneous leishmaniasis 4889 sd 288 visceral leishmaniasis risk maps predicted highest numbers infected people states minas gerais par visceral cutaneous leishmaniasis respectively conclusionssignificance spatially explicit highresolution incidence maps identified priority areas leishmaniasis control efforts targeted ultimate goal reduce disease incidence
https://doi.org/10.1016/j.amjmed.2013.09.002
Ridalva Dias Martins Felzemburgh|Guilherme S. Ribeiro|Federico Costa|Renato Barbosa Reis|José E. Hagan|Astrid X. T. O. Melendez|Deborah Bittencourt Mothé Fraga|Francisco S. Santana|Sharif B. Mohr|Balbino Lino dos Santos|Adriano Q. Silva|Andréia C. Santos|Romy R. Ravines|Wagner de Souza Tassinari|Marília Sá Carvalho|Mitermayer Galvão dos Reis|Albert I. Ko
Prospective Study of Leptospirosis Transmission in an Urban Slum Community: Role of Poor Environment in Repeated Exposures to the Leptospira Agent
2,014
Fundação Oswaldo Cruz|Ministry of Health|Universidade Federal da Bahia|Fundação Oswaldo Cruz|Ministry of Health|Universidade Federal da Bahia|Instituto de Saúde|Fundação Oswaldo Cruz|Ministry of Health|Yale University|Fundação Oswaldo Cruz|Ministry of Health|Fundação Oswaldo Cruz|Ministry of Health|Yale University|Fundação Oswaldo Cruz|Ministry of Health|Fundação Oswaldo Cruz|Ministry of Health|Fundação Oswaldo Cruz|Ministry of Health|Secretaria da Saúde|Fundação Oswaldo Cruz|Ministry of Health|Fundação Oswaldo Cruz|Ministry of Health|Fundação Oswaldo Cruz|Ministry of Health|Fundação Oswaldo Cruz|Ministry of Health|Escola Nacional de Saúde Pública|Ministry of Health|Fundação Oswaldo Cruz|Universidade Federal Rural do Rio de Janeiro|Escola Nacional de Saúde Pública|Ministry of Health|Fundação Oswaldo Cruz|Escola Nacional de Saúde Pública|Ministry of Health|Fundação Oswaldo Cruz|Fundação Oswaldo Cruz|Ministry of Health|Fundação Oswaldo Cruz|Ministry of Health|Yale University
background leptospirosis emerged urban health problem slum settlements rapidly spread worldwide created conditions ratborne transmission prospective studies performed determine disease burden identify risk factors infection provide information needed guide interventions marginalized communities methodologyprincipal findings enrolled followed cohort 2003 residents slum community city salvador brazil baseline oneyear serosurveys performed identify primary secondary leptospira infections defined respectively seroconversion fourfold rise microscopic agglutination titers used multinomial logistic regression models evaluate risk exposures acquiring primary secondary infection total 51 leptospira infections identified among 1585 79 participants completed oneyear followup protocol crude infection rate 378 per 1000 personyears secondary infection rate 23 times higher primary infection rate 717 311 infections per 1000 personyears respectively male gender 288 95 ci 140591 lower per capita household income 054 95 ci 030098 increase 1 per person per day independent risk factors primary infection contrast 1534 year age group 1082 95 ci 1388508 proximity residence open sewer 095 091099 increase 1 distance significant risk factors secondary infection conclusionssignificance study found slum residents high risk 3 per year acquiring leptospira infection reinfection frequent event occurs regions slum settlements proximity open sewers effective prevention leptospirosis therefore require interventions address infrastructure deficiencies contribute repeated exposures among slum inhabitants
https://doi.org/10.1093/occmed/kqp114
Katarzyna Chyl|Bartosz Kossowski|Agnieszka D?bska|Magdalena ?uniewska|Anna Banaszkiewicz|Agata ?elechowska|Stephen J. Frost|W. Einar Mencl|Marek Wypych|Artur Marchewka|Kenneth R. Pugh|Katarzyna Jednoróg
Prereader to beginning reader: changes induced by reading acquisition in print and speech brain networks
2,017
Instytut Biologii Do?wiadczalnej im. Marcelego Nenckiego|Instytut Biologii Do?wiadczalnej im. Marcelego Nenckiego|Warsaw University of Technology|Instytut Biologii Do?wiadczalnej im. Marcelego Nenckiego|Instytut Biologii Do?wiadczalnej im. Marcelego Nenckiego|University of Warsaw|Instytut Biologii Do?wiadczalnej im. Marcelego Nenckiego|Instytut Biologii Do?wiadczalnej im. Marcelego Nenckiego|Haskins Laboratories|Haskins Laboratories|Instytut Biologii Do?wiadczalnej im. Marcelego Nenckiego|Instytut Biologii Do?wiadczalnej im. Marcelego Nenckiego|Haskins Laboratories|Yale University|University of Connecticut|Instytut Biologii Do?wiadczalnej im. Marcelego Nenckiego
background literacy acquisition demanding process induces significant changes brain especially spoken written language networks nevertheless largescale paediatric fmri studies still limited methods analyzed fmri data show individual differences reading performance correlate brain activation speech print 111 children attending kindergarten first grade examined group differences matched subset emergentreaders prereaders results across entire cohort individual differences analysis revealed reading skill positively correlated magnitude activation difference words symbol strings left superior temporal inferior frontal fusiform gyri group comparisons matched subset pre emergentreaders showed higher activity emergentreaders left inferior frontal precentral postcentral gyri individual differences activation natural versus vocoded speech also positively correlated reading skill primarily left temporal cortex however contrast studies adult illiterates group comparisons revealed higher activity prereaders compared readers frontal lobes printspeech coactivation observed readers individual differences analyses revealed positive correlation convergence reading skill left superior temporal sulcus conclusions results emphasise childs brain undergoes several modifications visual oral language systems process learning read also suggest printspeech convergence hallmark acquiring literacy
https://doi.org/10.3310/hsdr02350
Melissa Lamar|Robert S. Wilson|Lei Yu|Bryan D. James|Christopher C. Stewart|David A. Bennett|Patricia A. Boyle
Associations of literacy with diabetes indicators in older adults
2,018
Rush University Medical Center|Rush University|Rush University Medical Center|Rush University|Rush University Medical Center|Rush University|Rush University Medical Center|Rush University Medical Center|Rush University|Rush University Medical Center|Rush University|Rush University Medical Center
background literacy ability access understand utilise information concepts diverse sources ways promote good outcomes key successful ageing domainspecific health financial literacy particularly relevant older adults face increasingly complex health financial demands including related chronic conditions like type 2 diabetes therefore investigated associations literacy including health financial literacy diabetes indicators ie haemoglobin a1c blood glucose communitybased cohort study ageing methods participants 908 nondemented older adults age 81 years75 women rush memory aging project literacy measured using questions designed assess comprehension health financial information concepts yielded total score domainspecific health financial literacy scores nonfasting haemoglobin a1c blood glucose samples collected participants queried diabetes status medications diabetes visually inspected coded participants also underwent cognitive assessment medical history depressive symptom screening results separate multivariable linear regression models total p values lt003 health p values lt0009 literacy inversely associated haemoglobin a1c blood glucose levels adjusting age sex education hypertension global cognitive functioning depressive symptoms financial literacy inversely associated haemoglobin a1c levels adjusted models p004 sensitivity analyses conducted among individuals without diabetes revealed similar results conclusion lower literacy levels associated higher diabetes indicators particularly haemoglobin a1c suggestive longerterm glycaemic instability
https://doi.org/10.2196/19370
Sebastian Suggate|Eva Pufke|Heidrun Stoeger
Do fine motor skills contribute to early reading development?
2,016
University of Regensburg|University of Regensburg|University of Regensburg
background little known fine motor skills fms relate early literacy skills especially cognitive variables moreover lack distinction fms graphomotor writing skills may hampered previous work method germany kindergartners n 144 aged 61 recruited beginning formal reading instruction administered host fms early reading skills cognitive measures results analyses indicate fms related less strongly graphomotor skills emergent literacy skills controlling graphomotor cognitive skills fms generally explain unique variance emergent literacy skills conclusions link reading motor skills highly differential findings suggest pure fms played significant role early reading development however close cousin graphomotor skills even devoid cognitive knowledge letters implications practice already known topic fine motor skills fms considered important school readiness indicator fms play role cognition language development research suggests fms might important reading paper adds first study look differentially fms emergent literacy fms considered separately graphomotor handwriting skill links motor skills broad range emergent literacy cognitive skills investigated implications practice andor policy fms may important development graphomotor skills graphomotor skills appear turn linked reading fostering childrens graphomotor skills may important kindergarten
https://doi.org/10.2196/19264
Tong Gong|Cecilia Lundholm|Gustaf Rejnö|Carina Mood|Niklas Långström|Catarina Almqvist
Parental Socioeconomic Status, Childhood Asthma and Medication Use – A Population-Based Study
2,014
Karolinska Institutet|Karolinska Institutet|Karolinska Institutet|Swedish Institute|Stockholm University|Karolinska Institutet|Karolinska University Hospital|Karolinska Institutet
background little known parental socioeconomic status affects offspring asthma risk general population relation healthcare medication use among diagnosed children methods registerbased cohort study included 211520 children born april 2006 december 2008 followed december 2010 asthma diagnoses retrieved national patient register dispensed asthma medications prescribed drug register parental socioeconomic status income education retrieved statistics sweden associations parental socioeconomic status outcomes estimated cox proportional hazard regression results compared highest parental income level children exposed levels increased risk asthma first year life eg hazard ratio hr 119 95 confidence interval ci 109131 diagnosis hr 117 95 ci 108126 medications lowest quintile risk decreased first year especially among children lowest parental income quintile hr 084 95 ci 077092 diagnosis hr 080 95 ci 074086 medications compared children collegeeducated parents whose parents lower education increased risk childhood asthma regardless age children lowest parental education increased risk inpatient hr 207 95 ci 161265 outpatient hr 132 95 ci 118147 asthma diagnosis among diagnosed children families lower education used fewer controller medications whose parents college graduates conclusions findings indicate agevarying association parental income childhood asthma consistent inverse association regardless age parental education asthma incidence dispensed controller medications inpatient care investigated remedied
https://doi.org/10.1177/1740774515571917
Sara Evans?Lacko|Elaine Brohan|Ramin Mojtabai|Graham Thornicroft
Association between public views of mental illness and self-stigma among individuals with mental illness in 14 European countries
2,011
King's College London|King's College London|Johns Hopkins University|King's College London
background little known views public related selfstigma among people mental health problems despite increasing activity aimed reducing mental illness stigma little evidence guide inform specific antistigma campaign development messages used mass campaigns better understanding association public knowledge attitudes behaviours internalization stigma among people mental health problems needed method study links two large international datasets explore association public stigma 14 european countries eurobarometer survey individual reports selfstigma perceived discrimination empowerment among persons mental illness n 1835 residing countries global alliance mental illness advocacy networks gamian study results individuals mental illness living countries less stigmatizing attitudes higher rates helpseeking treatment utilization better perceived access information lower rates selfstigma perceived discrimination living countries public felt comfortable talking people mental illness less selfstigma felt empowered conclusions targeting general public mass antistigma interventions may lead virtuous cycle disrupting negative feedback engendered public stigma thereby reducing selfstigma among people mental health problems combined approach involving knowledge attitudes behaviour needed mass interventions facilitate disclosure positive social contact may effective improving availability information mental health issues facilitating access care helpseeking also show promise regard stigma
https://doi.org/10.1371/journal.pone.0290334
Kathleen M Griffiths|Helen Christensen|Anthony F. Jorm|Kimberley Evans|Chloe Groves
Effect of web-based depression literacy and cognitive–behavioural therapy interventions on stigmatising attitudes to depression
2,004
Centre for Mental Health|Australian National University|Center for Anxiety and Depression|Centre for Mental Health|Australian National University|Center for Anxiety and Depression|Centre for Mental Health|Australian National University|Center for Anxiety and Depression|Centre for Mental Health|Australian National University|Center for Anxiety and Depression|Centre for Mental Health|Australian National University|Center for Anxiety and Depression
background little known efficacy educational interventions reducing stigma associated depression aims investigate effects stigma two internet depression sites method sample 525 individuals elevated scores depression assessment scale randomly allocated depression information website bluepages cognitivebehavioural skills training website moodgym attention control condition personal stigma personal stigmatising attitudes depression perceived stigma perception people believe assessed intervention results relative control internet sites significantly reduced personal stigma although effects small bluepages effect perceived stigma moodgym associated increase perceived stigma relative control changes stigma mediated changes depression depression literacy cognitivebehavioural therapy literacy conclusions internet warrants investigation means delivering stigma reduction programmes depression
https://doi.org/10.1111/jcpp.12737
Cristina McKean|Darren Wraith|Patricia Eadie|Fallon Cook|Fiona Mensah|Sheena Reilly
Subgroups in language trajectories from 4 to 11 years: the nature and predictors of stable, improving and decreasing language trajectory groups
2,017
Newcastle University|Queensland University of Technology|University of Melbourne|Murdoch Children's Research Institute|Murdoch Children's Research Institute|University of Melbourne|Murdoch Children's Research Institute|Griffith University
background little known nature range prevalence different subgroups language trajectories extant population 4 11 years hinders strategic targeting design interventions particularly targeting whose difficulties likely persist methods childrens language abilities 4 11 years investigated specialist language longitudinal community cohort n 1910 longitudinal trajectory latent class modelling used characterise trajectories identify subgroups multinomial logistic regression used identify predictors associated language trajectories children followed results three language trajectory groups identified stable 94 participants lowdecreasing 4 lowimproving 2 range child family factors identified associated following either lowimproving lowincreasing language trajectory many shared lowimproving group associated mostly environmental risks nonenglishspeaking background social disadvantage childrens books home lowdecreasing group associated mainly biological risks low birth weight socioemotional problems lower family literacy learning disability conclusions 4 years services confident children low language remain low 11 years using rigid cutpoints language ability target interventions recommended due continued individual variability language development service delivery models incorporate monitoring time targeting according language abilities associated risks delivery continuum interventions across continuum need
https://doi.org/10.3389/fnut.2023.1245477
Jonathan I. Silverberg|Eric L. Simpson
Associations of Childhood Eczema Severity
2,014
Northwestern University|Oregon Health & Science University
background little known predictors eczema severity us population objectives sought determine distribution associations childhood eczema severity united states methods analyzed data 2007 national survey childrens health prospective questionnairebased study nationally representative sample 91642 children range 017 years results prevalence childhood eczema 1297 95 confidence interval 95 ci 12421353 670 95 ci 648692 mild disease 260 95 ci 239281 moderate disease 70 95 ci 5883 severe disease significant statewide variation distribution eczema severity raoscott 2 p 0004 highest rates severe disease midatlantic midwestern states univariate models eczema severity increased older age african american hispanic raceethnicity lower household income oldest child family home single mother lower paternalmaternal education level maternal general health maternalpaternal emotional health dilapidated housing garbage streets multivariate survey logistic regression models using stepwise backward selection moderatetosevere eczema associated older age lower household income fair poor maternal health inversely associated birthplace outside united states conclusions data indicate environmental andor lifestyle factors play important role eczema severity
https://doi.org/10.1080/01635581.2020.1856890
Thyra de Jongh|Ipek Gurol?Urganci|Vlasta Vodopivec?Jamšek|Josip Car|Rifat Atun
Mobile phone messaging for facilitating self-management of long-term illnesses
2,012
London School of Hygiene & Tropical Medicine|University of Ljubljana|University of Ljubljana|Imperial College London|Imperial College London|Global Fund to Fight AIDS, Tuberculosis and Malaria
background longterm illnesses affect significant proportion population developed developing countries mobile phone messaging applications short message service sms multimedia message service mms may present convenient costeffective ways supporting selfmanagement improving patients selfefficacy skills instance medication reminders therapy adjustments supportive messages objectives assess effects mobile phone messaging applications designed facilitate selfmanagement longterm illnesses terms impact health outcomes patients capacity selfmanage condition secondary objectives include assessment user evaluation intervention health service utilisation costs possible risks harms associated intervention search methods searched cochrane central register controlled trials centralthe cochrane library 2009 issue 2 medline ovidsp january 1993 june 2009 embase ovidsp january 1993 june 2009 psycinfo ovidsp january 1993 june 2009 cinahl ebscohost january 1993 june 2009 lilacs january 1993 june 2009 african health anthology january 1993 june 2009 also reviewed grey literature including trial registers reference lists articles selection criteria included randomised controlled trials rcts quasirandomised controlled trials qrcts controlled beforeafter cba studies interrupted time series studies least three time points intervention selected studies possible assess effects mobile phone messaging independent technologies interventions data collection analysis two review authors independently assessed studies inclusion criteria disagreements resolved third review author study design features characteristics target populations interventions controls results data extracted two review authors confirmed third primary outcomes interest health outcomes result intervention capacity selfmanage longterm conditions also considered patients providers evaluation intervention perceptions safety health service utilisation costs potential harms adverse effects included studies heterogeneous type condition addressed intervention characteristics outcome measures therefore metaanalysis derive overall effect size main outcome categories considered justified findings presented narratively main results included four randomised controlled trials involving 182 participants primary outcome health outcomes including physiological measures moderate quality evidence two studies involving people diabetes showing statistical difference text messaging interventions compared usual care email reminders glycaemic control hba1c frequency diabetic complications body weight moderate quality evidence one study hypertensive patients mean blood pressure proportion patients achieved blood pressure control significantly different intervention control groups statistically significant difference mean body weight groups moderate quality evidence one study asthma patients receiving text messaging intervention experienced greater improvements peak expiratory flow variability mean difference md 1112 95 confidence interval ci 1956 268 pooled symptom score comprising four items cough night symptoms sleep quality maximum tolerated activity md 036 95 ci 056 017 compared control group however study found significant differences groups impact forced vital capacity forced expiratory flow 1 second primary outcome capacity selfmanage condition moderate quality evidence one study diabetes patients receiving text messaging intervention demonstrated improved scores measures selfmanagement capacity selfefficacy diabetes score md 610 95 ci 045 1175 diabetes social support interview pooled score md 439 95 ci 285 592 show improved knowledge diabetes moderate quality evidence three studies effects treatment compliance one study showed increase hypertensive patients rates medication compliance intervention group md 890 95 ci 018 1762 compared control group another study statistically significant effect rates compliance peak expiratory flow measurement asthma patients text message prompts diabetic patients initially also resulted higher number blood glucose results sent back 460 email prompts 235 secondary outcome participants evaluation intervention low quality evidence two studies patients receiving mobile phone messaging support reported perceived improvement diabetes selfmanagement wanted continue receiving messages preferred mobile phone messaging email method access computerised reminder system secondary outcome health service utilisation low quality evidence two studies diabetes patients receiving text messaging support made comparable number clinic visits calls emergency hotline patients without support asthma patients total number office visits higher text messaging group whereas number hospital admissions higher control group small number trials included low overall number participants reviewed outcomes quality evidence best considered moderate authors conclusions found albeit limited indications certain cases mobile phone messaging interventions may provide benefit supporting selfmanagement longterm illnesses however significant information gaps regarding longterm effects acceptability costs risks interventions given enthusiasm socalled mhealth interventions currently implemented research issues needed
https://doi.org/10.2196/22161
Sharon Orrange|Arpna Patel|Wendy J. Mack|Julia Cassetta
Patient Satisfaction and Trust in Telemedicine During the COVID-19 Pandemic: Retrospective Observational Study
2,021
University of Southern California|University of Southern California|University of Southern California|University of Southern California
background los angeles county hub covid19 cases united states academic health centers rapidly deployed leveraged telemedicine permit uninterrupted care patients telemedicine enjoys high patient satisfaction yet little known level satisfaction crisis extent patient visitrelated factors trust play inperson visits eliminated objective aim study examine correlates patients satisfaction telemedicine visit methods retrospective observational study conducted singleinstitution urban academic medical center los angeles internal medicine patients aged 18 years completed telemedicine visit march 10th april 17th 2020 invited survey n1624 measures included patient demographics degree interpersonal trust patientphysician relationships using trust physician scale visitrelated concerns statistical analysis used descriptive statistics spearman rankorder correlation linear ordinal logistic regression results 1624 telemedicine visits conducted period 368 227 patients participated survey across study respondents satisfied 173365 474 satisfied n129 353 telemedicine visit higher physician trust associated higher patient satisfaction spearman correlation r051 plt001 visitrelated factors statistically significant correlation trust physician score technical issues telemedicine visit r016 concerns privacy r019 concerns cost r023 satisfaction telemedicine convenience r041 amount time spent r047 plt01 visitrelated factors associated patients satisfaction included fewer technical issues plt001 less concern privacy plt001 cost p02 successful facetoface video plt001 patient variable significant positive association income level trust physician r018 plt001 younger age associated higher satisfaction telemedicine visit p005 conclusions calls redesigning primary care covid19 pandemic widespread adoption telemedicine patients satisfaction telemedicine covid19 pandemic high satisfaction shaped degree trust physician visitrelated factors patient factors widespread implications outpatient practices research visitrelated factors patientprovider connection telemedicine needed
https://doi.org/10.7759/cureus.12324
Rei Kobayashi|Masato Ishizaki
Relationship Between Health Literacy and Social Support and the Quality of Life in Patients With Cancer: Questionnaire Study
2,020
The University of Tokyo|The University of Tokyo
background low health literacy associated factors taking medication prescribed well poor health status increased hospitalization mortality risk identified risk factor decreased physical function older individuals health literacy becoming increasingly important issue increased number people affected cancer must make complicated treatment decisions health literacy shown positively associated quality life qol social support identified important addressing healthrelated problems reducing relative risk mortality patients cancer however studies examined relationship health literacy social support age qol objective aim study examine effects health literacy social support age qol patients cancer methods anonymous selfadministered online questionnaire conducted march 28 30 2017 japan patients lung stomach colon cancer voluntarily registered internet survey company survey covered basic attributes health literacy social support qol european health literacy survey questionnaire comprehensive measure health literacy instrument used measure health literacy japanese version social support scale used measure social support japanese version functional assessment cancer therapygeneral 7item version assessment tool used measure qol results total 735 survey invitations randomly sent patients lung stomach colorectal cancer responses obtained 619 822 response rate significant effects qol patients lung stomach colon cancer observed health literacy social support age interactions health literacy social support social support age health literacy social support interaction variables also showed significant effect qol patients 50 years older younger 50 years conclusions results study revealed higher health literacy social support age associated qol patients cancer addition relationship qol stronger social support health literacy findings suggest importance health literacy social support indicate social support greater effect qol health literacy qol patients cancer aged younger 50 years lower 50 years older therefore elucidating needs patients strengthening social support based needs may improve qol
https://doi.org/10.1371/journal.pntd.0003466
Julie Ayre|Erin Cvejic|Carissa Bonner|Robin Turner|Stephen D. Walter|Kirsten McCaffery
Effects of health literacy, screening, and participant choice on action plans for reducing unhealthy snacking in Australia: A randomised controlled trial
2,020
University of Sydney|University of Sydney|University of Sydney|University of Otago|McMaster University|Impact|University of Sydney
background low health literacy associated poorer health outcomes key strategy address health literacy universal precautions approach recommends using healthliterate design health interventions targeting people low health literacy approach advantages health literacy assessment tailoring required however action plans may effective tailored health literacy study evaluated impact health literacy action plan type unhealthy snacking people high bmi type 2 diabetes aim 1 effective method action plan allocation aim 2 methods findings performed 2stage randomised controlled trial australia 14 february 6 june 2019 total 1769 participants mean age 498 years sd 117 561 female n 992 mean bmi 329 kgm2 sd 87 296 selfreported type 2 diabetes n 523 randomised 1 3 allocation methods random health literacy screening participant selection 1 2 action plans reduce unhealthy snacking standard versus literacysensitive regression analysis evaluated impact health literacy newest vital sign nvs allocation method action plan reduction selfreported serves unhealthy snacks primary outcome 4week followup secondary outcomes perceived extent unhealthy snacking difficulty using plans habit strength action control analyses controlled age level education language spoken home diabetes status baseline habit strength baseline selfreported serves unhealthy snacks average nvs score 36 6 sd 20 participants reported consuming 250 serves snacks average per week baseline sd 280 regarding aim 1 398 participants random allocation arm completed followup 677 average people scoring 1 sd mean health literacy consumed 100 fewer serves per week using literacysensitive action plan compared standard action plan 95 ci 005 195 p 0039 whereas scoring 1 sd mean consumed 30 fewer serves using standard action plan compared literacysensitive action plan 95 ci 63 122 p 0529 although difference reach statistical significance addition observed nonsignificant action plan health literacy nvs interaction b 325 95 ci 655 005 p 0054 regarding aim 2 1177 participants across 3 allocation method arms completed followup 665 effect allocation method reduction unhealthy snacking including effect health literacy screening compared participant selection b 179 95 ci 016 373 p 0067 key limitations include lowmoderate retention use singleoccasion selfreported primary outcome reporting number extreme yet plausible snacking scores rendered interpretation challenging adverse events assessed conclusions study observed nominal improvements effectiveness action plans tailored health literacy however improvements reach statistical significance costs associated strategies compared universal precautions need investigation study highlights importance considering differential effects health literacy intervention effectiveness trial registration australia new zealand clinical trial registry actrn12618001409268
https://doi.org/10.1371/journal.pmed.1003602
Jolyn Hersch|Alexandra Barratt|Jesse Jansen|Les Irwig|Kevin McGeechan|Gemma Jacklyn|Hazel Thornton|Haryana M. Dhillon|Nehmat Houssami|Kirsten McCaffery
Use of a decision aid including information on overdetection to support informed choice about breast cancer screening: a randomised controlled trial
2,015
University of Sydney|University of Sydney|University of Sydney|University of Sydney|University of Sydney|University of Sydney|University of Leicester|University of Sydney|University of Sydney|University of Sydney
background mammography screening reduce breast cancer mortality however women unaware inconsequential disease also detected screening leading overdiagnosis overtreatment aimed investigate whether including information overdetection breast cancer decision aid would help women aged around 50 years make informed choice breast screening methods communitybased parallelgroup randomised controlled trial new south wales australia using random cohort women aged 4850 years recruitment study done telephone women eligible mammography past 2 years personal strong family history breast cancer computer program randomly assigned 879 participants either intervention decision aid comprising evidencebased explanatory quantitative information overdetection breast cancer mortality reduction false positives control decision aid including information breast cancer mortality reduction false positives participants interviewers masked group assignment primary outcome informed choice defined adequate knowledge consistency attitudes screening intentions assessed telephone interview 3 weeks random allocation primary outcome analysed women completed relevant followup interview questions fully trial registered australian new zealand clinical trials registry number actrn12613001035718 findings january 2014 july 2014 440 women allocated intervention group 439 assigned control group 21 women intervention group 20 controls lost followup ten women assigned intervention 11 controls answer questions attitudes therefore 409 women intervention group 408 controls analysed primary outcome 99 24 409 women intervention group made informed choice compared 63 15 408 control group difference 9 95 ci 314 p00017 compared controls women intervention group met threshold adequate overall knowledge 122419 29 vs 71419 17 difference 12 95 ci 618 p00001 fewer women expressed positive attitudes towards screening 282409 69 vs 340408 83 14 920 p00001 fewer women intended screened 308419 74 vs 363419 87 13 819 p00001 conceptual knowledge alone considered 203 50 409 women intervention group made informed choice compared 79 19 408 control group p00001 interpretation information overdetection breast cancer provided within decision aid increased number women making informed choice breast screening becoming better informed might mean women less likely choose screening funding australian national health medical research council
https://doi.org/10.2196/19985
Claire Henderson|Elaine Brohan|Sarah Clément|Paul Williams|Francesca Lassman|Oliver Schauman|Lisa Dockery|Simone Farrelly|Joanna Murray|Caroline Murphy|Mike Slade|Graham Thornicroft
Decision aid on disclosure of mental health status to an employer: feasibility and outcomes of a randomised controlled trial
2,013
King's College London|King's College London|King's College London|King's College London|King's College London|King's College London|King's College London|King's College London|King's College London|King's College London|King's College London|King's College London
background many mental health service users delay avoid disclosing condition employers experience anticipation discrimination however nondisclosure precludes ability request reasonable adjustments intervention studies support decisionmaking disclosure employer aims determine whether decision aid effect sustained beyond immediate impact determine whether largescale trial feasible optimise designs larger trial decision aid method exploratory randomised controlled trial rct london participants randomly assigned use decision aid plus usual care usual care alone followup 3 months primary outcomes stage decisionmaking b decisional conflict c employmentrelated outcomes trial registration number nct01379014 results recruited 80 participants interventions completed 36 40 intervention group total 71 participants followed intentiontotreat analysis showed reduction decisional conflict significantly greater intervention group among controls mean improvement 227 sd 152 v 112 sd 181 p 0005 intervention group controls fulltime employment followup p 003 conclusions observed reduction decisional conflict regarding disclosure number potential benefits next need tested definitive trial
https://doi.org/10.1002/pbc.24527