ENTITY
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DEFINITION
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ALIASES
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NAME
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C0007531
The blind sac or outpouching area of the LARGE INTESTINE that is below the entrance of the SMALL INTESTINE. It has a worm-like extension, the vermiform APPENDIX.
Caecum structure|Cecums|Cecum structure|cecal|Ceco-|Cecum|Cecum structure (body structure)|Caecum|Caecal|caecal|Cecal|Intestinum crassum caecum|Cecum, NOS|cecum|CECUM|ceco|LARGE INTESTINE, CECUM|Cecum/Cecal|caecum|Caecum, NOS
Cecum
C0004585
null
null
Bacilan
C0007033
A cytosolic carbonic anhydrase isoenzyme primarily expressed in ERYTHROCYTES, vascular endothelial cells, and the gastrointestinal mucosa. EC 4.2.1.-
Carbonic Anhydrase Isoenzyme B|Carbonic Anhydrase I|Carbonic Anhydrase B|Anhydrase B, Carbonic|Carbonic anhydrase, B
Carbonic Anhydrase I
C1427033
null
TUDOR3|TUDOR DOMAIN-CONTAINING PROTEIN 5|tudor domain containing 5|FLJ34823|TDRD5 gene|TDRD5
TDRD5 gene
C1427033
null
TUDOR3|TUDOR DOMAIN-CONTAINING PROTEIN 5|tudor domain containing 5|FLJ34823|TDRD5 gene|TDRD5
TDRD5 gene
C0038762
Inorganic or organic oxy acids of sulfur which contain the RSO2(OH) radical.
acid sulfonic|Acids, Sulfonic|sulfonic acid
Sulfonic Acids
C0064582
A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
α-hydroxypropionic acid|2 Hydroxypropionic Acid|Lactic acid, unspecified form|Lactic Acid, unspecified form|Acidum lacticum|ácido láctico|lactic acid|Lactic acid, NOS|2-Hydroxypropanoic acid|2-Hydroxypropionic Acid|Lactic acid-containing product|2-Hydroxypropionic acid|2-Hydroxypropanoic Acid|Lacticum acidum|lactic acid, unspecified form|LACTIC ACID, UNSPECIFIED FORM|Lactic Acid, Unspecified Form|2 Hydroxypropanoic Acid|Lactic acid|Milk acid|α-hydroxypropanoic acid|Lactic Acid|Lactic Acid, Unspecified form|Milchsäure|Lactic acid (substance)|Product containing lactic acid (medicinal product)|LACTIC ACID
lactic acid
C0241266
null
abscess subcutaneous|subcutaneous abscess|SUBCUTANEOUS ABSCESS|abscesses subcutaneous
Subcutaneous Abscess
C0017436
A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.
Gentamicins|Gentamycins
Gentamicins
C1263666
null
advanced cirrhosis|Advanced cirrhosis (disorder)
Advanced cirrhosis
C0033559
(11 alpha,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-en-1-oic acid (PGE(1)); (5Z,11 alpha,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid (PGE(2)); and (5Z,11 alpha,13E,15S,17Z)-11,15-dihydroxy-9-oxoprosta-5,13,17-trien-1-oic acid (PGE(3)). Three of the six naturally occurring prostaglandins. They are considered primary in that no one is derived from another in living organisms. Originally isolated from sheep seminal fluid and vesicles, they are found in many organs and tissues and play a major role in mediating various physiological activities.
prostaglandin E|E series prostaglandin-containing product|prostaglandin E (PGE)|pge|Prostaglandin PGE|Prostaglandin E|Prostaglandins E|E series prostaglandin (substance)|prostaglandin e|E series prostaglandin|PGE|Product containing E series prostaglandin (product)
Prostaglandins E
C0311392
Objective evidence of disease perceptible to the examining healthcare provider.
Sign|Physical finding|Physical sign, NOS|physical findings|find physical|physical finding|Sign, NOS|Physical sign|Physical finding, NOS|Sign (finding)|SIGNS|physical signs
Physical findings
C0018916
A vascular anomaly due to proliferation of BLOOD VESSELS that forms a tumor-like mass. The common types involve CAPILLARIES and VEINS. It can occur anywhere in the body but is most frequently noticed in the SKIN and SUBCUTANEOUS TISSUE. (from Stedman, 27th ed, 2000)
Strawberry mark|Haemangioma - morphology|Hemangioma, no International Classification of Diseases for Oncology subtype|Benign Hemangioma|Haemangioma of unspecified site|Benign haemangioma|haemangiomas|benign hemangiomas|Angioma|Hemangioma|haemangioma|Hemangiomata|Hemangioma, no International Classification of Diseases for Oncology subtype (morphologic abnormality)|Hemangioma, any site|Hemangiomas|hemangiomas|Hemangioma (disorder)|benign hemangioma|Benign hemangioma|HEMANGIOMA, BENIGN|HEMANGIOMA|Haemangioma|Hemangioma of unspecified site|hemangioma|Haemangioma, NOS|Benign Angioma|Hemangioma - morphology|Benign hemangioma (morphologic abnormality)|Angioma, NOS|Hemangioma, no ICD-O subtype|Hemangioma, NOS
Hemangioma
C1082344
A genus of brown-rot fungi in the family Coriolaceae. The biologically active ingredients of its species have potential pharmaceutical value.
Genus Antrodia|Antrodias|Genus Antrodia (organism)|Antrodia
Antrodia
C0085416
A large increase in oxygen uptake by neutrophils and most types of tissue macrophages through activation of an NADPH-cytochrome b-dependent oxidase that reduces oxygen to a superoxide. Individuals with an inherited defect in which the oxidase that reduces oxygen to superoxide is decreased or absent (GRANULOMATOUS DISEASE, CHRONIC) often die as a result of recurrent bacterial infections.
burst respiratory|oxidative burst|Bursts, Oxidative|respiratory burst (leukocyte)|Burst, Oxidative|burst oxidative|metabolic burst|respiratory burst|Respiratory Burst|Respiratory Bursts|Oxidative Burst|respiratory burst after phagocytosis|leukocyte oxidative burst|Burst, Respiratory|Oxidative Bursts|Bursts, Respiratory|metabolic burst after phagocytosis|oxidative burst after phagocytosis
Respiratory Burst
C0039654
A phorbol ester found in CROTON OIL with very effective tumor promoting activity. It stimulates the synthesis of both DNA and RNA.
Phorbol Myristate Acetate|Myristate Acetate, Phorbol|TPA|12 Myristoyl 13 acetylphorbol|Phorbol 13-Acetate, 12-O-Tetradecanoyl|12-Myristoyl-13-acetylphorbol|12-O-tetradecanoylphorbol-13-acetate|PMA (phorbol myristate acetate)|12 O Tetradecanoyl Phorbol 13 Acetate|Tetradecanoylphorbol Acetate|PMA|13-Acetate, 12-O-Tetradecanoyl Phorbol|12-O-Tetradecanoyl Phorbol 13-Acetate|PHORBOL 12-MYRISTATE 13-ACETATE DIESTER|Tetradecanoic acid, 9a-(acetyloxy)-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1H-cyclopropa(3,4)benz(1,2-e)azulen-9-yl ester, (1aR-(1aalpha,1bbeta,4abeta,7aalpha,7balpha,8alpha,9beta,9aalpha))-|Acetate, Phorbol Myristate|TPA (tetradecanoylphorbol acetate)|Acetate, Tetradecanoylphorbol|tetradecanoylphorbol acetate|TPA (Phorbol Ester)
Tetradecanoylphorbol Acetate
C0066131
null
Met-Leu-Phe
methionyl-leucyl-phenylalanine
C0086767
An araliaceous genus of plants that contains a number of pharmacologically active agents used as stimulants, sedatives, and tonics, especially in traditional medicine. Sometimes confused with Siberian ginseng (ELEUTHEROCOCCUS).
Panax ginseng|Ginseng|jen shen|Renshens|Shinseng|Jen Shen|Panax|panax|Panaxs|Shens, Jen|Shen, Jen|shinseng|ginseng|Ginsengs|Ninjin|Ninjins|Schinsengs|Schinseng|Jen Shens|Shinsengs|renshen|Renshen
Panax
C0001563
The giving of drugs, chemicals, or other substances by mouth.
administration oral|Oral Drug Administrations|PO administration|Administration of drug or medicament via oral route (procedure)|Oral Drug Administration|oral medication administration|Administration of drug or medicament via oral route|Administrations, Oral|Oral Administrations|Administration, Oral Drug|Medication administration: oral|per os administration|Drug Administration, Oral|oral administration|Oral Administration|oral enteral administration|Administrations, Oral Drug|Drug Administrations, Oral
Administration, Oral
C1037315
A plant genus of the family Stemonaceae. Members contain STILBENES and phenyl BENZOFURANS.
Stemonas|Stemona
Stemona
C0002062
Organic nitrogenous bases. Many alkaloids of medical importance occur in the animal and vegetable kingdoms, and some have been synthesized. (Grant & Hackh's Chemical Dictionary, 5th ed)
alkaloids|Alkaloid, NOS|alkaloid|Product containing alkaloid (product)|Alkaloid-containing product|Alkaloid (substance)|Alkaloids|Alkaloid
Alkaloids
C0010592
A cyclic undecapeptide from an extract of soil fungi. It is a powerful immunosupressant with a specific action on T-lymphocytes. It is used for the prophylaxis of graft rejection in organ and tissue transplantation. (From Martindale, The Extra Pharmacopoeia, 30th ed).
Cyclosporine-containing product|cyclosporin a|Ciclosporin|Ciclosporinum|cyclosporin A|ciclosporins|Ciclosporin-containing product|Cyclosporin a|Ciclosporina|Ciclosporin A|Ciclosporin (substance)|cyclosporine|ciclosporin|cyclosporin|Ciclosporine|CYA - Cyclosporine A|Product containing ciclosporin (medicinal product)|Cyclosporin|cycloSPORINE|CYCLOSPORINE|CyA|cyclosporine a|CsA|CYSP|CYA|CYA - Ciclosporin A|Cyclosporine|Cyclosporine Modified|CSA - Ciclosporin A|CSA - Cyclosporine A|Cyclosporine A|Cyclosporin A
cyclosporine
C0012200
A nitrosamine derivative with alkylating, carcinogenic, and mutagenic properties.
N-ethyl-N-nitroso-ethanamine|diethylnitrosamine|dena|N-Nitrosodiethylamine|DENA|N,N-diethylnitrosamine|Ethanamine, N-ethyl-N-nitroso-|Nitrosodiethylamine|NDEA|N-NITROSODIETHYLAMINE|N Nitrosodiethylamine
Diethylnitrosamine
C0028925
A pentacyclic triterpene that occurs widely in many PLANTS as the free acid or the aglycone for many SAPONINS. It is biosynthesized from lupane. It can rearrange to the isomer, ursolic acid, or be oxidized to taraxasterol and amyrin.
oleanolic acid|Olean-12-en-28-oic acid, 3-hydroxy-, (3beta)-|Oleanolic Acid|Oleanol|OLEANOLIC ACID
oleanolic acid
C0969677
A natural tocopherol and one of the most potent antioxidant tocopherols. It exhibits antioxidant activity by virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus. It has four methyl groups on the 6-chromanol nucleus. The natural d form of alpha-tocopherol is more active than its synthetic dl-alpha-tocopherol racemic mixture.
Alpha-tocopherol|3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol|.Alpha.-Tocopherol, D-|(+)-α-tocopherol|alpha Tocopherol|(R,R,R)-α-tocopherol|D-alpha-tocopherol (substance)|R,R,R-alpha-Tocopherol|(+)-alpha-Tocopherol|alpha-Tocopherol preparation|Alpha-Tocopherol|(2R)-2,5,7,8-TETRAMETHYL-2-[(4R,8R)-4,8,12-TRIMETHYLTRIDECYL]CHROMAN-6-OL|alpha-tocopherol|d-alpha-Tocopherol|d-alpha Tocopherol|d-Alpha-Tocopherol|alpha tocopherol|D-alpha-tocopherol|(+/-)-alpha-Tocopherol|.alpha.-tocopherol, D-|ALPHA-Tocopherol|d alpha Tocopherol|Tocopherol, d-alpha|d-α-tocopherol|.ALPHA.-Tocopherol|2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)chroman-6-ol|.alpha.-tocopherol, d-|(+-)-alpha-Tocopherol|d-alpha-tocopherol|Alpha-tocopherol (substance)|Alpha-tocopherol-containing product|ALPHA-TOCOPHEROL, D-|.ALPHA.-TOCOPHEROL, D-|dl-alpha tocopherol|3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol|Product containing alpha-tocopherol (medicinal product)|(2R,4'R,8'R)-α-tocopherol|ALPHA-TOCOPHEROL|Alpha tocopherol-containing product|d alpha tocopherol|.alpha.-tocopherol|.Alpha.-Tocopherol|alpha-Tocopherol|.ALPHA.-TOCOPHEROL
alpha tocopherol
C0969677
A natural tocopherol and one of the most potent antioxidant tocopherols. It exhibits antioxidant activity by virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus. It has four methyl groups on the 6-chromanol nucleus. The natural d form of alpha-tocopherol is more active than its synthetic dl-alpha-tocopherol racemic mixture.
Alpha-tocopherol|3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol|.Alpha.-Tocopherol, D-|(+)-α-tocopherol|alpha Tocopherol|(R,R,R)-α-tocopherol|D-alpha-tocopherol (substance)|R,R,R-alpha-Tocopherol|(+)-alpha-Tocopherol|alpha-Tocopherol preparation|Alpha-Tocopherol|(2R)-2,5,7,8-TETRAMETHYL-2-[(4R,8R)-4,8,12-TRIMETHYLTRIDECYL]CHROMAN-6-OL|alpha-tocopherol|d-alpha-Tocopherol|d-alpha Tocopherol|d-Alpha-Tocopherol|alpha tocopherol|D-alpha-tocopherol|(+/-)-alpha-Tocopherol|.alpha.-tocopherol, D-|ALPHA-Tocopherol|d alpha Tocopherol|Tocopherol, d-alpha|d-α-tocopherol|.ALPHA.-Tocopherol|2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)chroman-6-ol|.alpha.-tocopherol, d-|(+-)-alpha-Tocopherol|d-alpha-tocopherol|Alpha-tocopherol (substance)|Alpha-tocopherol-containing product|ALPHA-TOCOPHEROL, D-|.ALPHA.-TOCOPHEROL, D-|dl-alpha tocopherol|3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol|Product containing alpha-tocopherol (medicinal product)|(2R,4'R,8'R)-α-tocopherol|ALPHA-TOCOPHEROL|Alpha tocopherol-containing product|d alpha tocopherol|.alpha.-tocopherol|.Alpha.-Tocopherol|alpha-Tocopherol|.ALPHA.-TOCOPHEROL
alpha tocopherol
C0028925
A pentacyclic triterpene that occurs widely in many PLANTS as the free acid or the aglycone for many SAPONINS. It is biosynthesized from lupane. It can rearrange to the isomer, ursolic acid, or be oxidized to taraxasterol and amyrin.
oleanolic acid|Olean-12-en-28-oic acid, 3-hydroxy-, (3beta)-|Oleanolic Acid|Oleanol|OLEANOLIC ACID
oleanolic acid
C0070760
null
2,6-dimethyl-2,5- heptadien-4-one|diisopropylideneacetone
phorone
C0043552
mixture of polysaccharides, proteins, and ash, of variable concentration, derived from the cell walls or the entire cell of yeast, commonly Saccharomyces cerevisiae; is anticomplementary, absorbing the C3 component of complement, and is used in assaying properdin.
zymosan|Zymosans|Zymosan
Zymosan
C1515654
null
null
In Vitro Model
C0872896
null
hops|Hops extract|Hops|Humulus lupulus extract|Humulus lupulus extract (substance)|HOPS
hops extract
C0872896
null
hops|Hops extract|Hops|Humulus lupulus extract|Humulus lupulus extract (substance)|HOPS
hops extract
C0033692
Glycoproteins which have a very high polysaccharide content.
proteoglycans|Proteoglycans|Proteoglycan (substance)|proteoglycan|Proteoglycan
Proteoglycan
C0043552
mixture of polysaccharides, proteins, and ash, of variable concentration, derived from the cell walls or the entire cell of yeast, commonly Saccharomyces cerevisiae; is anticomplementary, absorbing the C3 component of complement, and is used in assaying properdin.
zymosan|Zymosans|Zymosan
Zymosan
C0599524
DITERPENES with three LACTONES and a unique tert-butyl group, which are found in GINKGO plants along with BILOBALIDES.
ginkgolides|ginkgolide
Ginkgolides
C0969616
null
null
levopimaradiene synthase
C0031586
Tumor-promoting compounds obtained from CROTON OIL (Croton tiglium). Some of these are used in cell biological experiments as activators of protein kinase C.
Esters, Phorbol|Phorbol esters|phorbol ester|Phorbol Ester|phorbol esters
Phorbol Esters
C0041113
A class of terpenes (the general formula C30H48) formed by the condensation of six isoprene units, equivalent to three terpene units.
triterpenes|Triterpene (substance)|triterpene|Triterpene|Triterpenoids
Triterpenes
C0908145
A subtype of non-receptor protein tyrosine phosphatases that includes two distinctive targeting motifs; an N-terminal motif specific for the INSULIN RECEPTOR, and a C-terminal motif specific for the SH3 domain containing proteins. This subtype includes a hydrophobic domain which localizes it to the ENDOPLASMIC RETICULUM.
Protein-Tyrosine Phosphatase HA2|Protein Tyrosine Phosphatase, Non Receptor Type 1|Protein Tyrosine Phosphatase 1B|Protein Tyrosine Phosphatase, Non-Receptor Type 1|Protein Tyrosine Phosphatase HA2|PTPase HA2|PTPase 1B
protein tyrosine phosphatase, non-receptor type 1
C1188198
null
Alnus incana subsp. hirsuta|Alnus inokumai|Alnus inokumae|Alnus incana var. hirsuta
Alnus hirsuta
C0053530
A pentacyclic lupane-type triterpene derivative of betulin (isolated from the bark of Betula alba, the common white birch) with antiinflammatory, anti-HIV and antineoplastic activities. Betulinic acid induces apoptosis through induction of changes in mitochondrial membrane potential, production of reactive oxygen species, and opening of mitochondrial permeability transition pores, resulting in the release of mitochondrial apogenic factors, activation of caspases, and DNA fragmentation. Although originally thought to exhibit specific cytotoxicity against melanoma cells, this agent has been found to be cytotoxic against non-melanoma tumor cell types including neuroectodermal and brain tumor cells.
Betulinic Acid|betulinic acid|Mairin|(3beta)-3-Hydroxy-lup-20(29)-en-28-oic Acid|3-hydroxylup-20(29)-en-28-oic acid|BETULINIC ACID|betulic acid|BA|beta-betulinic acid
betulinic acid
C0303231
An inorganic or organic substance that contains the metallic element lead either in its positive-2 or 4 valence state. Lead compounds have a wide variety of applications in industry. Exposure to lead compounds affects the lungs, central nervous system and kidneys. Lead compounds are possible mutagens and are reasonably anticipated to be human carcinogens. The substance may be associated with an increased risk of developing lung and stomach cancer. (NCI05)
Lead compound (substance)|Lead compound, NOS|Lead Compound|Lead compounds
Lead compound
C0023277
A parasitic hemoflagellate of the subgenus Leishmania leishmania that infects man and animals including rodents. The Leishmania mexicana complex causes both cutaneous (LEISHMANIASIS, CUTANEOUS) and diffuse cutaneous leishmaniasis (LEISHMANIASIS, DIFFUSE CUTANEOUS) and includes the subspecies amazonensis, garnhami, mexicana, pifanoi, and venezuelensis. L. m. mexicana causes chiclero ulcer, a form of cutaneous leishmaniasis (LEISHMANIASIS, CUTANEOUS) in the New World. The sandfly, Lutzomyia, appears to be the vector.
mexicana, Leishmania leishmania|Leishmania mexicana (organism)|mexicana, Leishmania|mexicanas, Leishmania leishmania|leishmania mexicana, Leishmania|LEISHMANIA MEXICANA|Leishmania mexicana|Leishmania leishmania mexicanas|Leishmania leishmania mexicana|Leishmania (Leishmania) mexicana|Leishmania mexicanas
Leishmania mexicana
C0119192
null
Gypenoside III|Gynosaponin C|Ginsenoside Rb1|GRb 1|Arasaponin E1|Panax saponin E|Pseudoginsenoside D
ginsenoside Rb1
C0387583
An inducibly-expressed subtype of prostaglandin-endoperoxide synthase. It plays an important role in many cellular processes and INFLAMMATION. It is the target of COX2 INHIBITORS.
Cyclooxygenase 2|Prostaglandin Synthase, COX-2|Prostaglandin H Synthase 2|Cyclooxygenase 2 (substance)|Cyclo Oxygenase II|2 cyclooxygenase|COX 2 Prostaglandin Synthase|COX-2 Prostaglandin Synthase|pghs-2|cyclooxygenase 2|Cyclooxygenase-2|PGHS-2|Synthase, COX-2 Prostaglandin|Prostaglandin-endoperoxide synthase isoform 2|PTGS2|Cyclo-Oxygenase II|h prostaglandin synthase-2|cyclooxygenase-2|Prostaglandin H Synthase-2
cyclooxygenase 2
C0591154
null
Beconase|Becotide|Becodisks|Becloforte|Sanasthmyl|Becodisk|Propaderm|becotide|beconase
Beconase
C0591154
null
Beconase|Becotide|Becodisks|Becloforte|Sanasthmyl|Becodisk|Propaderm|becotide|beconase
Beconase
C0996995
null
Arctium lappa|Burdock, Greater|Greater Burdocks|Greater Burdock|Burdocks|arctium lappa|Burdocks, Greater|Gobos|Gobo|Gobou
Arctium lappa
C0127061
A lignan which is structurally similar to secoisolariciresinol with an additional lactone involving the gamma-gamma' carbons; plant lignan that is a dietary precursor to the mammalian lignan enterodiol.
matai-resinol|Matairesinol
matairesinol
C0064980
null
null
ligustilide
C0010762
A superfamily of hundreds of closely related HEMEPROTEINS found throughout the phylogenetic spectrum, from animals, plants, fungi, to bacteria. They include numerous complex monooxygenases (MIXED FUNCTION OXYGENASES). In animals, these P-450 enzymes serve two major functions: (1) biosynthesis of steroids, fatty acids, and bile acids; (2) metabolism of endogenous and a wide variety of exogenous substrates, such as toxins and drugs (BIOTRANSFORMATION). They are classified, according to their sequence similarities rather than functions, into CYP gene families (>40% homology) and subfamilies (>59% homology). For example, enzymes from the CYP1, CYP2, and CYP3 gene families are responsible for most drug metabolism.
Cytochrome P450 Protein|Cytochrome P450 Superfamily|Cytochrome P 450 Superfamily|cytochrome P450 enzyme system|cytochrome p 450|P450|CYP (cytochrome P450)|cytochrome p-450|Cytochrome p-450|P 450 Enzymes|Cytochrome P-450 Superfamily|CYP450|Cytochrome p450 enzyme|P-450 Enzymes, Cytochrome|Cytochrome p-450 enzyme|Cytochrome P450 Family|Superfamily, Cytochrome P-450|CYP450 Family|Cytochrome P 450 Enzymes|Enzymes, Cytochrome P-450|Cytochrome P-450 Enzyme System|Cytochrome P 450 Enzyme System|cytochrome p450|P-450 Enzymes|Cytochrome P 450|Cytochrome P450 Enzyme|Cytochrome P450|Cytochrome P-450 Families|Cytochrome p450 enzyme (substance)|Cytochrome-P450|p450 cytochrome|Cytochrome p450|Superfamily, Cytochrome P450|Enzymes, P450|P450 Enzymes|Cytochrome p450 Families|Cytochrome P 450 Families|Cytochrome P-450 Enzymes|CYP|Cytochrome P-450|Superfamily, CYP450|CYP450 Superfamily|Enzymes, P-450|cytochrome P450|cytochromes p450
Cytochrome P450
C0040333
The type species of TOBAMOVIRUS which causes mosaic disease of tobacco. Transmission occurs by mechanical inoculation.
Tobacco mosaic virus|tobacco mosaic virus, TMV|Mosaic Viruses, Tobacco|Viruses, Tobacco Mosaic|tobacco mosaic virus|tobacco mosaic virus TMV|Mosaic Virus, Tobacco|Virus, Tobacco Mosaic|Tobacco Mosaic Viruses
Tobacco Mosaic Virus
C1136102
Proteins that form the CAPSID of VIRUSES.
Capsid Protein|Coat Proteins, Viral|Viral Outer Coat Protein|Viral Coat Proteins|Coat Proteins|Capsid|Capsid Proteins
Capsid Proteins
C0007004
A class of organic compounds composed of carbon, hydrogen, and oxygen in a ratio of Cn(H2O)n. The largest class of organic compounds, including STARCH; GLYCOGEN; CELLULOSE; POLYSACCHARIDES; and simple MONOSACCHARIDES.
Product containing carbohydrate (product)|CARBOHYDRATE|saccharide|Saccharide|Carbs|saccharides|Carbohydrate-containing product|Carbohydrates|Carbohydrate (substance)|Sugar|carbohydrate|Carbohydrate|Carbohydrate, NOS|carbohydrates|CARBOHYDRATES
Carbohydrates
C0815045
null
storage protein|storage proteins
Storage proteins
C0439879
A class of nonmetals such as arsenic that have some of the chemical properties of a metal.
Intermediate Metals|Semi-Metals|Metals, Intermediate|Semi Metals
Metalloids
C0004359
Endogenous tissue constituents that have the ability to interact with AUTOANTIBODIES and cause an immune response.
self antigen|autoantigens|Autologous Antigens|Autoantigen (substance)|Self Antigens|Antigens, Autologous|Self-Antigens|autoantigen|Autoantigen|self antigens
Autoantigens
C0119748
null
Anchors, GPI Membrane|Glycosyl Phosphatidylinositol Membrane Protein Anchors|Anchors, Glycosylphosphatidylinositol|Membrane Anchors, GPI|Glycoinositol Phospholipid Membrane Anchor|GPI Membrane Anchors|Glycosyl-Phosphatidylinositol Membrane Protein Anchors
Glycosylphosphatidylinositol Anchors
C0010798
Hemeproteins whose characteristic mode of action involves transfer of reducing equivalents which are associated with a reversible change in oxidation state of the prosthetic group. Formally, this redox change involves a single-electron, reversible equilibrium between the Fe(II) and Fe(III) states of the central iron atom (From Enzyme Nomenclature, 1992, p539). The various cytochrome subclasses are organized by the type of HEME and by the wavelength range of their reduced alpha-absorption bands.
Cytochrome|cytochromes|Cytochromes|cytochrome
Cytochromes
C0910406
null
HEV E ORF2 protein, Hepatitis E virus|open reading frame 2 protein, Hepatitis E virus
ORF2 protein, Hepatitis E virus
C0910406
null
HEV E ORF2 protein, Hepatitis E virus|open reading frame 2 protein, Hepatitis E virus
ORF2 protein, Hepatitis E virus
C0056467
null
Cre recombinase, Enterobacteria phage P1|bacteriophage P1 recombinase Cre
Cre recombinase, Enterobacteria phage P1
C0012203
A synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. It was also used formerly as a growth promoter in animals. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), diethylstilbestrol has been listed as a known carcinogen. (Merck, 11th ed)
3, 4-Bis(p-hydroxyphenyl)-3-hexene|Diethylstilbestrolum|3-Hexene,3,4-bis(p-hydroxyphenyl)-|3,4-Bis(p-hydroxyphenyl)-3-hexene|Diethylstilbestrol preparation|DES preparation|4,4'-dihydroxy-alpha,beta-diethylstilbene|Stilbestrol|4,4'-dihydroxy-α,β-diethylstilbene|Diethylstilbenediol|trans-Diethylstilbesterol|Diethylstilboestrol|(E)-4,4'-(1,2-diethyl-1,2-ethenediyl)bisphenol|4,4'-Dihydroxy-.alpha., .beta.-diethylstilbene|Diethylstilbestrol (substance)|Diethylstilbestrol-containing product|Trans-bis-(hydroxy-4-phenyl)-3,4 hexene-3|trans-bis-(hydroxy-4-phenyl)-3,4 hexene-3|stilbestrol|Diethylstilbestrol|Phenol, 4,4'-(1,2-diethyl-1,2-ethenediyl)bis-, (E)-|diethylstilbestrol (DES)|DES|Palestrol|trans-Diethylstilboesterol|α,α'-diethyl-(E)-4,4'-stilbenediol|Dietilestilbestrol|3,4-bis(p-hydroxyphenyl)-3-hexene|alpha,alpha'-diethylstilbenediol|Estrogen, Stilbene|trans-4,4'-(1,2-diethyl-1,2-ethenediyl)bisphenol|(E)-3,4-bis(4-hydroxyphenyl)-3-hexene|Product containing diethylstilbestrol (medicinal product)|trans-Diethylstilbestrol|Alpha,alpha'-diethylstilbenediol|Stilboestrol|diethylstilbestrol|diethylstilbestrolum|Stilbene Estrogen|DIETHYLSTILBESTROL|Diéthylstilbestrol|4,4'-Dihydroxy-alpha,beta-diethylstilbene|Stilbestrol preparation|.alpha., .alpha.'-Diethylstilbenediol
diethylstilbestrol
C0043454
(S-(E))-3,4,5,6,8,10-Hexahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione. One of a group of compounds known under the general designation of resorcylic acid lactones. Cis, trans, dextro and levo forms have been isolated from the fungus Gibberella zeae (formerly Fusarium graminearum). They have estrogenic activity, cause toxicity in livestock as feed contaminant, and have been used as anabolic or estrogen substitutes.
Zearalenone|Toxin, F2|1H-2-Benzoxacyclotetradecin-1,7(8H)-dione, 3,4,5,6,9,10-hexahydro-14,16-dihydroxy-3-methyl-, (S-(E))-|Toxin, F-2|F2 Toxin|F-2 toxin|Zearalenone (substance)|F 2 Toxin|F-2 Toxin
Zearalenone
C0061202
An isoflavonoid derived from soy products. It inhibits PROTEIN-TYROSINE KINASE and topoisomerase-II (DNA TOPOISOMERASES, TYPE II); activity and is used as an antineoplastic and antitumor agent. Experimentally, it has been shown to induce G2 PHASE arrest in human and murine cell lines and inhibits PROTEIN-TYROSINE KINASE.
GENISTEIN|5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one|Prunetol|prunetol|Genestein|4',5,7-trihydroxyisoflavone|genisterin|4',5, 7-Trihydroxyisoflavone|genisteol|Genisterin|genestein|Genistein|genistein|5,7,4'-trihydroxyisoflavone|sophoricol|5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one|Genisteol|4',5,7-Trihydroxyisoflavone
genistein
C1373098
null
Estrogen Receptor Antagonists|Estrogen Receptor Antagonists [MoA]|Estrogen Receptor Inhibitor
Estrogen Receptor Antagonists [MoA]
C0195893
Producing a lesion in the posteroventral portion of the medial GLOBUS PALLIDUS to treat PARKINSON DISEASE and other extrapyramidal disorders. The placement of the lesion is aided by STEREOTACTIC TECHNIQUES and imaging procedures.
pallidotomy|Pallidotomies|Pallidotomy|Pallidotomy (procedure)
Pallidotomy
C1288948
null
Entire right hand (body structure)|Entire right hand
Entire right hand
C0040005
An essential amino acid occurring naturally in the L-form, which is the active form. It is found in eggs, milk, gelatin, and other proteins.
L Threonine|L-threonine|l-threonine|2-Amino-3-hydroxybutyric acid|Threonine (substance)|L-Threonin|threonine|L-alpha-amino-beta-hydroxybutyric acid|Treonina|L-Threonine|THREONINE|L-α-amino-β-hydroxybutyric acid|(2S,3R)-2-Amino-3-hydroxybutanoic acid|Threoninum|threonine (Thr)|Threonine|(2S,3R)-(-)-Threonine|L-(-)-Threonine|L-2-Amino-3-hydroxybutyric acid|thr|Thr|(2S)-threonine
threonine
C1305923
<p><b>Description:</b>A polypeptide resulting from the translation of a gene.</p>
polypeptide|Polypeptide, NOS|ActClassPolypeptide|Polypeptide|polypeptides|Product containing polypeptide (product)|Polypeptide-containing product|Polypeptide (substance)
Polypeptides
C0008141
A linear polysaccharide of beta-1->4 linked units of ACETYLGLUCOSAMINE. It is the second most abundant biopolymer on earth, found especially in INSECTS and FUNGI. When deacetylated it is called CHITOSAN.
Chitin|chitin
Chitin
C1332324
Apoptosis Regulation Genes encode Apoptosis Regulator proteins, which either promote or impede the initiation, progress, or rate of apoptosis.
null
Apoptosis Regulation Gene
C1332324
Apoptosis Regulation Genes encode Apoptosis Regulator proteins, which either promote or impede the initiation, progress, or rate of apoptosis.
null
Apoptosis Regulation Gene
C0230715
The dark-staining region of a sarcomere, in which myosin thick filaments are present; the center is traversed by the paler H zone, which in turn contains the M line. [ISBN:0321204131]
a band|Anisotropic band|Discus anisotropicus (Stria A)|A-band|anisotropic disc|transverse disc|Q disc|A band (cell structure)|A disc|A band
A band
C1518271
The dorsal surface of the early vertebrate embryo that gives rise to the nervous system.
Neuroectoderm|Neurectoderm|Neuroectoderms|neuroectoderm|Ectomesenchyme
Neuroectoderm
C0206116
The third type of glial cell, along with astrocytes and oligodendrocytes (which together form the macroglia). Microglia vary in appearance depending on developmental stage, functional state, and anatomical location; subtype terms include ramified, perivascular, ameboid, resting, and activated. Microglia clearly are capable of phagocytosis and play an important role in a wide spectrum of neuropathologies. They have also been suggested to act in several other roles including in secretion (e.g., of cytokines and neural growth factors), in immunological processing (e.g., antigen presentation), and in central nervous system development and remodeling.
mesoglia|gitter cell|Hortega cell|perivascular glial cell|Microglial cell|Microglial cells set|Small glial cell|microglia|microgliocyte|Microglia|Microglial Cell|Set of microglial cells|Microgliocyte (cell)|small glial cell|Microgliocyte|microglial cell|Gitter cell
Microglia
C0521329
Of or relating to the spine or spinal cord.
Spinal|spinal
Spinal
C0005025
null
BENZALKONIUM|Benzalkonium-containing product|Benzalkonium (substance)|Benzalkonium|Product containing benzalkonium (medicinal product)|benzalkonium
benzalkonium
C0597360
process by which functional receptors appear, migrate, and disappear at the cell surface; involves gene expression, protein biosynthesis, posttranslational modification, membrane transport, and degradation; can be used to index interspecies receptor gene implants.
receptor expression
receptor expression
C0020498
A disease of elderly men characterized by large osteophytes that bridge vertebrae and ossification of ligaments and tendon insertions.
Hyperostosis, Diffuse Idiopathic Skeletal|Forestier's Disease|Disease, Forestier's|Disease, Forestier|Disease, Forestier-Rotes|Ankylosing Hyperostoses, Vertebral|Diffuse idiopathic skeletal hyperostosis|DISH|Vertebral Ankylosing Hyperostosis|Forestier Disease|ankylosing hyperostosis vertebral|Disseminated idiopathic skeletal hyperostosis (disorder)|Disseminated idiopathic skeletal hyperostosis|Forestier-Rotes Disease|Diffuse Idiopathic Skeletal Hyperostosis|Forestier Rotes Disease|Ankylosing vertebral hyperostosis|Forestier-Rotes-Querol syndrome|Forestier's disease|DIFFUSE IDIOPATHIC SKELETAL HYPEROSTOSIS|Ankylosing Vertebral Hyperostosis with Tylosis|ANKYLOSING VERTEBRAL HYPEROSTOSIS WITH TYLOSIS|Vertebral Ankylosing Hyperostoses|forestier disease|DISH - Diffuse idiopathic skeletal hyperostosis|Hyperostosis, Vertebral Ankylosing|Ankylosing Hyperostosis, Vertebral|forestier's disease|Forestiers Disease|Ankylosing hyperostosis|Hyperostoses, Vertebral Ankylosing|diffuse idiopathic skeletal hyperostosis (DISH)
Hyperostosis, Diffuse Idiopathic Skeletal
C0026187
A TETRACYCLINE analog, having a 7-dimethylamino and lacking the 5 methyl and hydroxyl groups, which is effective against tetracycline-resistant STAPHYLOCOCCUS infections.
Minocycline|Minociclina|Minocycline (substance)|7-Dimethylamino-6-demethyl-6-deoxytetracycline|Product containing minocycline (medicinal product)|minocycline|(2E,4S,4aR,5aS,12aR)- 2-(amino-hydroxy-methylidene)- 4,7-bis(dimethylamino)-10,11,12a-trihydroxy-4a,5,5a,6- tetrahydro-4H-tetracene- 1,3,12-trione|Minocyclinum|(4S,4aS,5aR,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide|2-Naphthacenecarboxamide, 4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-, (4S-(4alpha,4aalpha,5aalpha,12aalpha))-|Minocycline-containing product|Minocyclin|Minociclinum|MINOCYCLINE
minocycline
C0002716
A fibrous protein complex that consists of proteins folded into a specific cross beta-pleated sheet structure. This fibrillar structure has been found as an alternative folding pattern for a variety of functional proteins. Deposits of amyloid in the form of AMYLOID PLAQUES are associated with a variety of degenerative diseases. The amyloid structure has also been found in a number of functional proteins that are unrelated to disease.
Amyloid|amyloids|Substance, Amyloid|Amyloid, NOS|Amyloid Substance|amyloid
Amyloid
C0025936
Laboratory mice that have been produced from a genetically manipulated EGG or EMBRYO, MAMMALIAN.
mouse transgenics|transgenic mouse|Transgenic Mouse|Transgenic Mice|mice transgenic|Transgenic mice|transgenic mice|Mouse, Transgenic
Mice, Transgenic
C0026187
A TETRACYCLINE analog, having a 7-dimethylamino and lacking the 5 methyl and hydroxyl groups, which is effective against tetracycline-resistant STAPHYLOCOCCUS infections.
Minocycline|Minociclina|Minocycline (substance)|7-Dimethylamino-6-demethyl-6-deoxytetracycline|Product containing minocycline (medicinal product)|minocycline|(2E,4S,4aR,5aS,12aR)- 2-(amino-hydroxy-methylidene)- 4,7-bis(dimethylamino)-10,11,12a-trihydroxy-4a,5,5a,6- tetrahydro-4H-tetracene- 1,3,12-trione|Minocyclinum|(4S,4aS,5aR,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide|2-Naphthacenecarboxamide, 4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-, (4S-(4alpha,4aalpha,5aalpha,12aalpha))-|Minocycline-containing product|Minocyclin|Minociclinum|MINOCYCLINE
minocycline
C1327413
The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:add, ISBN:0781735149]
cytokine production
cytokine production
C0599635
A class of porins that allow the passage of WATER and other small molecules across CELL MEMBRANES.
water transporter|Aquaporin|water channel|Water Channels|Channel Proteins, Water|Proteins, Water Channel|Aquaporin family protein|Channels, Water|Water Channel Proteins|AQP family protein|aquaporins|Aquaporin family protein (substance)|aquaporin|Aquaporins
water channel
C0599635
A class of porins that allow the passage of WATER and other small molecules across CELL MEMBRANES.
water transporter|Aquaporin|water channel|Water Channels|Channel Proteins, Water|Proteins, Water Channel|Aquaporin family protein|Channels, Water|Water Channel Proteins|AQP family protein|aquaporins|Aquaporin family protein (substance)|aquaporin|Aquaporins
water channel
C0036394
A nerve which originates in the lumbar and sacral spinal cord (L4 to S3) and supplies motor and sensory innervation to the lower extremity. The sciatic nerve, which is the main continuation of the sacral plexus, is the largest nerve in the body. It has two major branches, the TIBIAL NERVE and the PERONEAL NERVE.
Structure of sciatic nerve|N. ischiadicus|Nervus ischiadicus|Nerves, Sciatic|Sciatic Nerve|NERVE, SCIATIC|SCIATIC NERVE|Sciatic nerve|sciatic nerve|Sciatic Nerves|sciatic nerves|Nerve, Sciatic|Structure of sciatic nerve (body structure)|Sciatic nerve, NOS
Structure of sciatic nerve
C0229034
An autonomic plexus that is a subdivision of the celiac plexus and accompanies the pancreatic arteries.
Structure of pancreatic plexus (body structure)|Structure of pancreatic plexus|Pancreatic plexus|Pancreatic nerve plexus|Plexus pancreaticus|Plexus nervosus pancreaticus
Structure of pancreatic plexus
C1184808
a network like structure of nerves or blood vessels
plexus|Plexus
Plexus
C0017067
Clusters of multipolar neurons surrounded by a capsule of loosely organized CONNECTIVE TISSUE located outside the CENTRAL NERVOUS SYSTEM.
Ganglion|Ganglia|Nervous system ganglion, NOS|ganglia|Neural Ganglion|Structure of nervous system ganglion|ganglion|GANGLION|Nervous system ganglion|a group of nerve cell|neural ganglion|Ganglionic|Structure of nervous system ganglion (body structure)
Ganglia
C0459326
null
null
Peripheral nerve plexus
C0599635
A class of porins that allow the passage of WATER and other small molecules across CELL MEMBRANES.
water transporter|Aquaporin|water channel|Water Channels|Channel Proteins, Water|Proteins, Water Channel|Aquaporin family protein|Channels, Water|Water Channel Proteins|AQP family protein|aquaporins|Aquaporin family protein (substance)|aquaporin|Aquaporins
water channel
C0079541
Anterior midline brain, cranial, and facial malformations resulting from the failure of the embryonic prosencephalon to undergo segmentation and cleavage. Alobar prosencephaly is the most severe form and features anophthalmia; cyclopia; severe INTELLECTUAL DISABILITY; CLEFT LIP; CLEFT PALATE; SEIZURES; and microcephaly. Semilobar holoprosencepaly is characterized by hypotelorism, microphthalmia, coloboma, nasal malformations, and variable degrees of INTELLECTUAL DISABILITY. Lobar holoprosencephaly is associated with mild (or absent) facial malformations and intellectual abilities that range from mild INTELLECTUAL DISABILITY to normal. Holoprosencephaly is associated with CHROMOSOME ABNORMALITIES.
HPEC|Holoprosencephaly sequence|Familial alobar holoprosencephaly|Holoprosencephalies|Holoprosencephaly Sequence|holoprosencephaly|HPE, FAMILIAL|Single brain ventricle|HPE - Holoprosencephaly|Holoprosencephaly sequence (disorder)|Holoprosencephaly|Holoprosencephaly (HPE)
Holoprosencephaly
C0076088
Hexameric extracellular matrix glycoprotein transiently expressed in many developing organs and often re-expressed in tumors. It is present in the central and peripheral nervous systems as well as in smooth muscle and tendons. (From Kreis & Vale, Guidebook to the Extracellular Matrix and Adhesion Proteins, 1993, p93)
Tenascin Family|hexabrachion|Tenascin|tenascin|Cytotactin|Tenascin C|Tenascin-C|Hexabrachion
Tenascin
C0447962
null
Entire cranial bone (body structure)|Entire cranial bone
Entire cranial bone
C0022889
The portion of the ear located within the temporal bone that is involved in both hearing and balance and includes the semicircular canals, vestibule, and cochlea. (from American Heritage Dictionary online)
labyrinths|EAR, INNER|Inner Ear|Internal Ear|Ears, Inner|Ear, Internal|inner ear structure|Inner ear, NOS|auditory labyrinth|Ear, Inner|Inner Ears|ear labyrinths|Inner ear structure|Internal Ears|labyrinthine|Labyrinth|labyrinth (ear)|Internal ear|Labyrinth, NOS|Inner ear|Auris interna|INNER EAR|internal ear|Labyrinth (Ear)|labyrinth|ear labyrinth|Labyrinth structure|Ears, Internal|Labyrinthine|Inner ear structure (body structure)|Labyrinth structure (body structure)|inner ear|Labyrinths
Labyrinth
C0018497
Auditory sensory cells of organ of Corti, usually placed in one row medially to the core of spongy bone (the modiolus). Inner hair cells are in fewer numbers than the OUTER AUDITORY HAIR CELLS, and their STEREOCILIA are approximately twice as thick as those of the outer hair cells.
Inner Hair Cells|Inner Auditory Hair Cell|Hair Cell, Inner|Auditory Hair Cell, Inner|Inner hair cell (cell)|Inner Hair Cell of Organ of Corti|Cells, Inner Hair|inner hair cell|Cochlear Inner Hair Cell|cells hair inner|Cochlear Inner Hair Cells|Inner hair cell|Cochlear inner hair cell|Inner Hair Cell of the Organ of the Corti|Inner Hair Cell|Inner hair cell of organ of Corti|Inner Auditory Hair Cells|Hair Cells, Auditory, Inner|Cell, Inner Hair|Auditory Hair Cells, Inner|inner hair cells|Hair Cells, Inner|Hair Cell, Auditory, Inner
Inner Auditory Hair Cells
C0055502
null
CCK-22|CCK-22 C-terminal fragment|cholecystokinin-22 C-terminal fragment
cholecystokinin 22 C-terminal fragment
C0751623
A primary malignant neoplasm in a patient who has been already diagnosed with a primary malignant neoplasm in another anatomic site.
Cancers, Second|second primary cancer|Cancer, Second Primary|Second Cancer|Second Cancers|Second Primary Malignant Neoplasm|second cancers|cancer second|Second Primary Cancer|Cancers, Second Primary|second cancer|Second Primary Cancers|Cancer, Second
Second Primary Cancers