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C0023411 | A genus of gram-positive, facultatively anaerobic bacteria whose growth is dependent on the presence of a fermentable carbohydrate. It is nonpathogenic to plants and animals, including humans. | Betacoccus|LEUCONOSTOC|Leukonostoc|Leuconostoc, NOS|Genus Leuconostoc|Leuconostoc|leuconostoc|Genus Leuconostoc (organism)|Leuconostoc species | Leuconostoc |
C0206588 | Proteins that regulate transcription via interaction with chromatin and basal transcription machinery at the promoter regions of genes. Nuclear receptors are ligand-dependent transcription factors including steroids, retinoids, vitamin D, unliganded thyroid hormone, and orphan receptors (unknown ligands). Coregulators (coactivators or corepressors) are important in mediating these interactions and thereby modulate positive or negative receptor activity. | Nuclear Receptors|nuclear receptor|nuclear receptors|Nuclear Receptor|Receptor, Nuclear | Receptors, Nuclear |
C0229985 | The edges of tissue removed in a surgery for assessment of the effectiveness of a surgical procedure in achieving the local control of a neoplasm and the adequacy of tumor removal. When the margin is negative or not involved by tumor (e.g., CANCER) it suggests all of the tumor has been removed by the surgery. | Excision Margin|Surgical margins|Surgical Margin|Margin, Resection|Margins of excision|margin|Resection Margins|Margins, Surgical|Resection Margin|Margin, Surgical|surgical margin|Excision Margins|Surgical margins (body structure)|Surgical Margins|excision margins|Margins, Resection|Margins of Excision | Surgical margins |
C0011429 | The hard portion of the tooth surrounding the pulp, covered by enamel on the crown and cementum on the root, which is harder and denser than bone but softer than enamel, and is thus readily abraded when left unprotected. (From Jablonski, Dictionary of Dentistry, 1992) | Dentine of tooth|Dentin structure (body structure)|Dentin structure|Dentine structure|Dentines|Dentin|dentin|Dentin of tooth|dentine|Dentine|Dentinum|Dentins | Dentin |
C0023759 | Either of the two fleshy, full-blooded margins of the mouth. | mouth lips|Lip|Vermillion of the Lip|Labial part of mouth|Labial (qualifier value)|LIP|Labium oris|labio|Lip, NOS|Labia oris|Mouth margin|Lips|Lip structure (body structure)|lips face|Lip structure|mouth lip|Labial|lips mouth|lip|labials|Labio-|labial|lip mouth|Lips of mouth|LIPS|lipped|of lips mouth|lip structure|lips|labios|face lip | Lip structure |
C0026367 | The most posterior teeth on either side of the jaw, totaling eight in the deciduous dentition (2 on each side, upper and lower), and usually 12 in the permanent dentition (three on each side, upper and lower). They are grinding teeth, having large crowns and broad chewing surfaces. (Jablonski, Dictionary of Dentistry, 1992, p821) | Molar tooth structure|molars|Molar Tooth|molar tooth|Molar|Permanent molar tooth|Molar tooth, NOS|TOOTH, MOLAR|molar (dental)|Dens molaris|Molar tooth|Structure of molar tooth|Structure of molar tooth (body structure)|Structure of permanent molar tooth (body structure)|molar|Structure of permanent molar tooth|Molars | Molar tooth |
C0180459 | Any device component shaped like a disk, especially those used for data storage. | disk device|Disc|Disk Device|Disk|DISC | Disks (device) |
C0966123 | null | Prime & Bond NT | Prime and Bond NT |
C1100757 | null | Prime & Bond 2.1 | prime and bond 2.1 |
C1100853 | null | NRC conditioner | non-rinse conditioner |
C0010384 | A preformed crown is a prefabricated device made of plastic or austenitic alloys or alloys containing 75 percent or greater gold and metals of the platinum group intended to be affixed temporarily to a tooth after removal of, or breakage of, the natural crown (that portion of the tooth that normally protrudes above the gums). It is intended for use as a functional restoration until a permanent crown is constructed. The device also may be intended for use as a functional restoration for a badly decayed deciduous (baby) tooth until the adult tooth erupts. | CROWN, PREFORMED|Crowns|Crowns (Dentistry)|dental crowns|Crown (physical object)|Dental prosthetic crown|Preformed dental crown (physical object)|Preformed dental crown|crown (dental)|Crown|dental crown | Prostheses, Dental, Fixed, Crown, Total, Temporary |
C0441697 | null | dye testing|test dye|dye test|Dye test (qualifier value)|dye tests|DT - Dye test | Dye test |
C0108342 | An agent composed of urea and hydrogen peroxide. As an earwax removal agent, carbamide peroxide releases, upon administration into the ear, oxygen and causes foaming which helps soften, loosen and remove excessive earwax. It is also used as a disinfectant and in dentistry for its teeth whitening effects. | Urea peroxide|Urea hydrogen peroxide-containing product|Carbamide peroxide (substance)|Product containing carbamide peroxide (medicinal product)|CARBAMIDE PEROXIDE|Carbamide peroxide-containing product|carbamide peroxide|Urea Peroxide|Urea Hydrogen Peroxide|Carbamide peroxide|Carbamide Peroxide|Hydrogen Peroxide, Urea|Urea hydrogen peroxide|Urea, compd. with hydrogen peroxide (H2O2) (1:1) | carbamide peroxide |
C1139855 | null | tags | Tags (device) |
C0303749 | null | bleaching|bleached|Bleach (substance)|bleach|Bleach, NOS | Bleach |
C0035191 | A thick substance that comes from plants or can be made in the laboratory from certain chemicals. Resins do not dissolve in water, and are used in plastics, varnishes, printing inks, medicine, and to make fabrics stiff. | Plant Hydrocarbon Secretion|Resins, Plant|Plant Resins|Resina|Resin|resins|resin | Resins, Plant |
C0000962 | The part of the pelvis that comprises the pelvic socket where the head of FEMUR joins to form HIP JOINT (acetabulofemoral joint). | acetabulum anatomy|Acetabulum (Anatomy)|Acetabulas|Cavity, Cotyloid|Bone structure of acetabulum (body structure)|Acetabulum|Cotyloid Cavity|Acetabular part of hip bone|Bone structure of acetabulum|ACETABULUM|Cavities, Cotyloid|Cotyloid Cavities|Acetabulums|acetabulum|Acetabula|Acetabulum, NOS | Bone structure of acetabulum |
C0441603 | null | null | capsulorrhaphy |
C1444783 | null | null | Instability |
C1306645 | An image produced on a radiosensitive surface by x-ray radiation that has penetrated and passed through a structure. | plain x-ray|x-ray|Skiagram|radiographs|Radiograph|roentgenogram|films plain|radiogram|skiagrams|Plain film|plain film|Radiographs|skiagram|Roentgenogram|Plain x-ray|x ray|x rayed|X-ray|Plain radiography|Plain radiography (procedure)|x rays|roentgenograms|Radiogram|radiograph|Roentgenography|x raying | Plain x-ray |
C0029064 | Facilities equipped for performing surgery. | OR - Operating room|Operating theatre|OPERATING ROOM|operating rooms|operating room|Operating Theatre|Operating Rooms|operating theatre|OT - Operating theatre|OR|operating theater|Operating rooms|Operating theatre (environment)|room operating|Operating room|Operating Room|Rooms, Operating|operating theaters|Operating Theater|operating theatres|Room, Operating | Operating Room |
C0041455 | The most common form of fibrillar collagen. It is a major constituent of bone (BONE AND BONES) and SKIN and consists of a heterotrimer of two alpha1(I) and one alpha2(I) chains. | Collagen type I|Collagen type I (substance)|Type I collagen|Collagen, Type I|type 1 collagen|Type 1 Collagen|collagen type i|Collagen vulgaris|Type I Collagen|Collagen Type 1|Collagen 1|Collagen I|Collagen Type I|Collagen, Type 1 | collagen type I |
C1282762 | null | Entire subcutaneous bursa (body structure)|Entire subcutaneous bursa | Entire subcutaneous bursa |
C0224844 | null | Achilles bursa|Bursa of tendo calcaneus|Tendo calcaneus bursa|Structure of calcaneal tendon bursa (body structure)|Calcaneal tendon bursa|Bursa of calcaneal tendon|Retrocalcaneal bursa|Bursa tendinis calcanei|Bursa of Achilles tendon|Structure of calcaneal tendon bursa|Bursa of Achilles|Subachilleal bursa | Bursa of Achilles |
C0278403 | Loose connective tissue lying under the DERMIS, which binds SKIN loosely to subjacent tissues. It may contain a pad of ADIPOCYTES, which vary in number according to the area of the body and vary in size according to the nutritional state. | hypoderm|Hypodermis|Subcutaneous tissue structure|Subcutaneous Tissues and Structures|Subcutaneous tissue, NOS|Tela subcutanea|subcutaneous tissue|hypodermis|Tissues, Subcutaneous|Fascia, Superficial|Subcutaneous tissue|SUBCUTANEOUS TISSUES: GENERAL TERMS|Subcutaneous Tissue|Subcutaneous connective tissue|Superficial fascia|Tissue, Subcutaneous|SUBCUTANEOUS TISSUES|Superficial Fascia|Hypoderm|Tela Subcutanea|superficial fascia|Subcutis|subcutaneous tissues|Subcutaneous tissue structure (body structure)|Subcutaneous connective tissue, NOS|Subcutaneous Tissues | Subcutaneous Tissue |
C0923870 | Spatial association relationship which describes the containment, adjacency and anatomical coordinates of physical anatomical entities. Examples: anatomical containment, anatomical adjacency, anatomical coordinate. | Anatomical location (property)|Anatomical location|Anatomical location (property) (qualifier value) | Anatomical location |
C0040508 | Total reconstruction of hip with prosthesis. | Total replacement of hip (procedure)|Total Hip Replacement|total hip arthroplasty|Prosthetic total arthroplasty of the hip|hip total replacement|total hip replacement|total hip replacement procedure|Insertion of hip prosthesis, total|Total Hip Replacements|Hip Replacement, Total|Total hip replacement|THR - Total hip replacement|TOTAL HIP ARTHROPLASTY|total hip replacement surgery|Hip Replacements, Total|total hip replacements|Total hip replacement (finding)|Total reconstruction of hip with prosthesis|Total replacement of hip|Total reconstruction of hip|Replacement, Total Hip|Replacements, Total Hip | Total Hip Replacement (procedure) |
C0019558 | The joint that is formed by the articulation of the head of FEMUR and the ACETABULUM of the PELVIS. | JOINT, HIP|Coxofemoral joint|coxofemoral joint|Hip joint structure|Coxal joint|Joint, Hip|Acetabulofemoral Joints|Hip joint structure (body structure)|HIP JOINT|Articulatio coxae|Articulatio coxofemoralis|Joints, Acetabulofemoral|hip joint|Coxofemoral Joint|Joints, Hip|Acetabulofemoral Joint|Hip joint|Hip Joint|Hip Joints|Hip joint, NOS|hip joints|Joint, Acetabulofemoral|Coxafemoral joint | Hip Joint |
C0017718 | amino sugar derivative of glucose, substituted at the 2 position, occurring in glycosaminoglycans and a variety of complex polysaccharides such as blood group substances. | Glycosamine|glycosamine|2-Amino-2-Deoxyglucose|Product containing glucosamine (medicinal product)|Glucosamine (substance)|glucosamines|2 Amino 2 Deoxyglucose|D-Glucosamine|Chitosamine|glucosamine|Glucosamine-containing product|Glucosamine|2-amino-2-deoxy-D-glucose|glucosamine products|D-Glucose, 2-amino-2-deoxy-|GLUCOSAMINE|Glucosamina | glucosamine |
C0017720 | An amino sugar (2-amino, 2-deoxyglucose) in cell membranes, Glucosamine Sulfate is believed to play a role in cartilage formation and repair. Long-term glucosamine sulfate treatment retards progression of knee osteoarthritis; the mechanism appears to involve glucosamine's role as an essential substrate for glycosaminoglycans and hyaluronic acid, needed for formation of the joint proteoglycan structural matrix. (NCI04) | glucosamine sulfate|GLUCOSAMINE SULFATE|Glucosamine Sulfate|Glucosamine sulfate (substance)|Glucosamine sulfate|glucosamine sulfates|Sulfate, Glucosamine|sulfate glucosamine | glucosamine sulfate |
C0409959 | Noninflammatory degenerative disease of the knee joint consisting of three large categories: conditions that block normal synchronous movement, conditions that produce abnormal pathways of motion, and conditions that cause stress concentration resulting in changes to articular cartilage. (Crenshaw, Campbell's Operative Orthopaedics, 8th ed, p2019) | knee osteoarthritis|Osteoarthritis of Knee|Osteoarthritis of knee (disorder)|Knee osteoarthritis|knee osteoarthrosis|Osteoarthritis of knee|Knee Osteoarthritides|Osteoarthritis of the Knee|OA - Osteoarthritis of knee|Knee DJD (degenerative joint disease)|Degenerative joint disease of knee|OSTEOARTHRITIS SUSCEPTIBILITY 6|OSTEOARTHRITIS OF KNEE|osteoarthritis of knee|Gonarthrosis|Osteoarthritis, Knee|OS6|Knee Osteoarthritis | Osteoarthritis, Knee |
C0040736 | Transplantation of an individual's own tissue from one site to another site. | Autogenous transplantation (procedure)|Autotransplantation|Autotransplantations|autotransplant|Transplantation, autogenous|autografting|Autologous Transplantations|Autograftings|autotransplants|Autologous Transplant|autografts|autotransplantation|Autologous transplantation|autograft|Autografting|Transplantations, Autologous|autologous transplantation|Autologous Transplantation|Autogenous transplantation|Transplantation, Autologous | Transplantation, Autologous |
C0003904 | Endoscopic examination, therapy and surgery of the joint. | Arthroscopic procedure (procedure)|Arthroscopy|MUSCULOSKELETAL SYSTEM: ENDOSCOPY|arthroscopy|Musculoskeletal system endoscopy (procedure)|Arthroscopy (procedure)|Arthroscopies|Arthroscopy, NOS|Musculoskeletal system endoscopy|Arthroscopic procedure | Arthroscopy |
C0003881 | The surgical fixation of a joint by a procedure designed to accomplish fusion of the joint surfaces by promoting the proliferation of bone cells. (Dorland, 28th ed) | joint fixation (surgical)|Ankylosis, surgical|Arthrodesis of unspecified joint|arthrodeses|Arthrodesis, NOS|arthrodesis|Arthrodesis (procedure)|Joint fusion|Ankylosis, artificial|joint arthrodesis|fusion joints|ankylosis (surgical)|Arthrodesis|syndesis|fusions joint|Syndesis|arthrodese|joint fusion|Arthrodeses | Arthrodesis |
C0003090 | Fixation and immobility of a joint. | Joint Ankylosis|Frozen joint|Joint ankylosis|Fusion of joint, NOS|Ankylosis of joint|Ankylosis, NOS|Ankylosis of joint, site unspecified|Joint fused|Ankylosis of joint (disorder)|Ankylosis (morphologic abnormality)|ankylosis|joint ankylosis|frozen joints|fusion of joint|Fusion of joint|joint fusion|Ankylosis|frozen joint|ANKYLOSIS|ankyloses|Ankyloses|ANKYLOSES | Ankylosis |
C0029408 | A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans. | Degenerative Arthritides|Osteoarthrosis, NOS|OSTEOARTHROSIS|primary OA|OA - Osteoarthritis|Degenerative Joint Disease|Hypertrophic polyarthritis|Osteoarthritis, degenerative|Osteoarthritis, NOS|Arthritides, Degenerative|JOINT DISEASE, DEGENERATIVE|degenerative disease joint|Degenerative joint disease, NOS|Hypertrophic polyarthritis, NOS|degenerative joint disease|o a|OA - Osteoarthrosis|Degenerative arthropathy|Degenerative polyarthritis|Degenerative arthritis, NOS|osteoarthrosis|Osteoarthrosis|ARTHRITIS, SENESCENT|Osteoarthrosis, unspecified whether generalized or localized|DEGENERATIVE JOINT DISEASE|Degenerative polyarthritis (disorder)|Hypertrophic arthritis|Osteoarthritis (disorder)|Arthritis, Degenerative|degenerative arthropathy|Osteoarthritides|oa|Degenerative arthropathy, NOS|osteoarthritis degenerative|degenerative arthritis|ARTHRITIS, HYPERTROPHIC|ARTHROPATHY, DEGENERATIVE|Osteoarthritis|arthritis degenerative|oas|a o|Degenerative Arthritis|arthritis osteoarthritis|Osteoarthrosis (OA)|Hypertrophic arthritis, NOS|degenerative disease joints|Degenerative joint disease|osteoarthritis arthritis|degenerative osteoarthritis|DJD|OSTEOARTHRITIS|OA|Degenerative polyarthritis, NOS|oa osteoarthritis|osteoarthritis|arthrosis|hypertrophic arthritis|Degenerative arthritis|Osteoarthroses|degenerative diseases joint | Degenerative polyarthritis |
C0917780 | null | Differentiation Antigens, Leukocyte, Human | Leukocyte Differentiation Antigens, Human |
C1384584 | null | Generalised osteoarthritis|Primary generalized hypertrophic osteoarthrosis|Osteoarthrosis, generalized, multiple sites|Generalized osteoarthritis|PGOA - Primary generalized osteoarthritis|Osteoarthrosis, generalized|Generalized osteoarthrosis|Degenerative joint disease involving multiple joints|Primary osteoarthritis|Primary generalised osteoarthritis|PGOA - Primary generalised osteoarthritis|Osteoarthrosis, generalized, involving multiple sites|Primary generalised hypertrophic osteoarthrosis|GOA - Generalised osteoarthritis|Osteoarthrosis (OA), primary, generalized|GOA - Generalized osteoarthritis|Primary generalized osteoarthritis|Generalized osteoarthritis (disorder)|Generalised osteoarthrosis|Polyarticular osteoarthritis|Primary generalised osteoarthrosis|Primary generalized osteoarthrosis | Generalized osteoarthritis |
C0039099 | The inner membrane of a joint capsule surrounding a freely movable joint. It is loosely attached to the external fibrous capsule and secretes SYNOVIAL FLUID. | Synovial membrane structure|synovial membranes|Synovial membrane structure (body structure)|membrane synovial|Synovial Membrane|Synovial layer|Membrana Synovialis Capsulae Articularis|Synovial tissue|Synovial stratum|synovium|synovial membrane|Synovial layer of articular capsule|Synovial membrane|Synovial membranes|Membranes, Synovial|Synovial Membranes|synovial tissue|Membrane, Synovial|Stratum synoviale|Synovial layer of articular capsule, NOS|SYNOVIAL MEMBRANE|Membrana synovialis|Synovium|Synovial membrane, NOS | Synovial Membrane |
C0933803 | null | Type A synoviocyte|Type A synovial cell | Type A synoviocyte |
C0079772 | A group of heterogeneous lymphoid tumors representing malignant transformations of T-lymphocytes. | T-cell lymphoma|T-Cell and NK-Cell Non-Hodgkin's Lymphoma|T-cell non-Hodgkin lymphoma|T-Cell Non-Hodgkin's Lymphoma|T-Cell Lymphomas|T-cell and NK-cell non-Hodgkin lymphoma|T-cell lymphoma (clinical)|T-cell lymphoma (disorder)|T-Cell and NK-Cell Non-Hodgkin Lymphoma|lymphoma t-cell|T-Cell Lymphoma|T Cell Lymphoma|T cell lymphoma|cells lymphoma t|Lymphomas, T-Cell|T-cell non-Hodgkin's lymphoma|T-Cell Non-Hodgkin Lymphoma|lymphoma t cell|t-cell lymphoma|non-Hodgkin's T-cell lymphoma|Non-Hodgkin's T-Cell Lymphoma|Malignant lymphoma, T-cell type|t cell lymphoma|T-cell and NK-cell non-Hodgkin's lymphoma|cell lymphomas t|Lymphoma, T-Cell|cell lymphoma t|Lymphoma, T Cell|Lymphoma, non-Hodgkin lymphoma, T-cell | T-Cell Lymphoma |
C0032568 | null | Polyp, inflammatory|Inflammatory polyp|Pseudopolyposis, NOS|Inflammatory polyp (morphologic abnormality)|pseudopolyps|Pseudopolyposis|inflammatory polyp|Pseudopolyp, NOS|pseudopolyposis|Inflammatory pseudopolyp|pseudopolyp|Pseudopolyp|Pseudopolyp, inflammatory|inflammatory polyps | Inflammatory polyp |
C0859865 | A benign polypoid growth in the external or middle ear. | polyp ear|ear polyp|Otic polyp|Aural polyp|Polyp of ear|aural polyps|Aural Polyp|ear polyps|Ear Polyp|aural polyp|Polyp of Ear|Polyp of the Ear | Otic polyp |
C0525064 | Persons with any degree of loss of hearing that has an impact on their activities of daily living or that requires special assistance or intervention. | hard hearing person|Persons, Deaf|Person, Hearing Disabled|Hard of Hearing Persons|Hearing Impaired Person|Disabled Persons, Hearing|DEAF|Person, Deaf|Deaf Person|Person, Hearing Impaired|Persons, Hearing Disabled|Deaf|Hearing Impaired Persons|Deaf Persons|Hearing Disabled Persons|deaf|Persons With Hearing Impairments|Hearing Disabled Person|Persons, Hearing Impaired | Hearing Impaired Persons |
C0229089 | The eye positioned in the right orbit. | eye right|right eye|Oculus Dexter|Right eye|Right orbital region|Right eye structure|OD - right eye|eyes right|Right orbital part of face|OD|Right Eye|Right eye structure (body structure)|RE - Right eye | Right eye |
C1267211 | null | Entire duct (organ)|Entire duct|Entire duct (organ) (body structure) | Entire duct |
C0836913 | A concavity in a surface, especially an anatomical depression. | fossa|Fossa | Fossa |
C0014871 | The area covering the terminal portion of ESOPHAGUS and the beginning of STOMACH at the cardiac orifice. | Gastro-oesophageal junction|Junction, Gastroesophageal|Cardio-oesophageal junction structure|Gastroesophageal Junction|gastroesophageal junction|Oesophagogastric junction|GASTROESOPHAGEAL JUNCTION|Cardioesophageal junction|esophagogastric sphincter|Cardioesophageal junction structure (body structure)|Junctions, Gastroesophageal|cardio-esophageal junction|Esophagogastric Junction|Gastro-esophageal junction|Cardio-oesophageal junction|esophagogastric junction|Cardioesophageal junction structure|Gastroesophageal Junctions|gastro-esophageal junction|Gastroesophageal junction|Esophagogastric junction|Junction, Esophagogastric|Gastrooesophageal junction|Cardio-esophageal junction | Esophagogastric Junction |
C0405388 | null | Microdochectomy (procedure) | Microdochectomy |
C0080264 | Use of ultrasound for imaging the breast. The most frequent application is the diagnosis of neoplasms of the female breast. | Mammary Ultrasonography|ultrasound of breast|breasts ultrasound|Ultrasonographies, Mammary|Mammographies, Ultrasonic|Ultrasonography of breast|breast ultrasound|Breast Ultrasonographies|Breast Ultrasonography|Mammographies, Ultrasound|Ultrasonography of breast (procedure)|Ultrasound Mammography|Breast ultrasonography|Ultrasonographies, Breast|Mammography, Ultrasonic|mammography ultrasound|Ultrasonography, Breast|Ultrasonic Mammographies|ultrasound breast|Mammography, Ultrasound|breast ultrasounds|Ultrasound Mammographies|Ultrasonic Mammography|ultrasound mammography|Mammary Ultrasonographies|Ultrasonic examination of breast | Ultrasonography, Mammary |
C0018180 | A vascular connective tissue formed on the surface of a healing wound, ulcer, or inflamed tissue. It consists of new capillaries and an infiltrate containing lymphoid cells, macrophages, and plasma cells. | of granulation tissue|Granulation tissue|Granulation tissue (morphologic abnormality)|Granulation Tissue|Granulation tissue, NOS|Granulation of tissue|Granulation of tissue (finding)|Tissue granulation|GRANULATION TISSUE|granulation tissue|Granulation Tissues|tissue granulation|granulation tissues|Tissues, Granulation|granulation of tissue|Tissue, Granulation | Granulation Tissue |
C0193769 | null | Operative procedure on the thyroid gland, NOS|Operative procedure on the thyroid gland|THYROID GLAND: GENERAL AND MISCELLANEOUS OPERATIVE PROCEDURES|thyroid surgery|Operation on thyroid gland (procedure)|surgery thyroid|OPERATIVE PROCEDURES ON THE THYROID GLAND|Thyroid gland operation | Operation on thyroid gland |
C0225331 | A tissue composed of bundles of collagenous white fibers between which are rows of connective tissue cells. | Fibrous Tissue|fibrous tissue|Fibrous tissue (body structure)|Fibrous tissue | Fibrous tissue |
C0018131 | The survival of a graft in a host, the factors responsible for the survival and the changes occurring within the graft during growth in the host. | graft survival|Graft Survivals|Survival, Graft|Survivals, Graft|survival graft | Graft Survival |
C0750138 | null | access vascular|accesses vascular | vascular access |
C0149781 | Pneumothorax occurring without traumatic injury to the chest or lung. [HPO:probinson] | pneumothorax spontaneous|SPONTANEOUS PNEUMOTHORAX|Spontaneous pneumothorax NOS|Spontaneous pneumothorax|Spontaneous pneumothorax (disorder)|Spontaneous collapsed lung|spontaneous pneumothorax | Spontaneous pneumothorax |
C0396565 | null | lung resectioning|excision lung|pulmonary resection|Excision of lung|Pulmonary resection|resection of lung|Resection of lung NOS|lung resection|Lung excision (procedure)|Resection of lung|lung resections|Excision of lung NOS | Lung excision |
C0005758 | Visible accumulations of fluid within or beneath the epidermis. | skin vesicle|Blisters|bullae|Vesication|vesication|Blister (morphologic abnormality)|bullous lesion|Blister|BLISTER|Blebs|Lesion, Bullous|Lesions, Bullous|Blister, NOS|Blistering|Bullae|Bleb|Bullous Lesion|BULLA|BLISTERS|Bullous Lesions|blister|bullous lesions|Vesications|bulla|Bulla | Bulla |
C0002766 | A form of therapy that employs a coordinated and interdisciplinary approach for easing the suffering and improving the quality of life of those experiencing pain. | therapy, pain|Pain Control|controlling pain|pain controll|pain relieved|Pain Management|Pain management|pain controlling|analgesias|Pain--Treatment|Pain Therapy|relieving pain|Pain Managements|therapy pain|Management, Pain|management pain|controlled pain|managing pain|pain management|analgesia|Analgesia|Managing pain|Managements, Pain|managed pain|pain relieving|Pain, Pain Management|Pain management (procedure)|pain therapy|pain therapies | Pain management |
C0184567 | Intensely discomforting, distressful, or agonizing sensation associated with trauma or disease, with well-defined location, character, and timing. | Pains, Acute|pain acute|Acute Pains|Acute pain (finding)|Acute pain|acute pain|Acute Pain|Pain, Acute | Acute onset pain |
C0240602 | null | narcotic use|narcotics use|OPIOID USE|opioids use|NARCOTIC USE | opioid use |
C0233818 | Reduced ability to plan, poor decision making. | Impaired Judgement|JUDGMENT IMPAIRMENT|Defective judgement|impaired judgment|Judgment Impaired|impairs judgement|Impaired judgement|Impaired judgement (finding)|Defective judgment|JUDGEMENT IMPAIRED|impaired judgement|Impaired Judgment | Impaired judgement |
C0181598 | A mechanical pump which also includes a control system and an energy supply. It receives blood from the left ventricle and delivers it to the aorta, thus helping the heart to pump sufficient blood to the body. | Left Ventricular Assist Device|Left ventricular assist device (physical object)|assist devices left ventricular|assist device left ventricular|LEFT VENTRICULAR ASSIST DEVICE|left ventricular assist devices|left ventricular assist device|LVAD|assisted device left ventricular | Left ventricular assist device |
C0003611 | Surgical removal of the vermiform appendix. (Dorland, 28th ed) | appendicectomy|Appendectomy|Excision of appendix|Excision of appendix, NOS|Appendicectomy, NOS|Appendectomy, NOS|Appendectomies|Excision of appendix (procedure)|appendectomies|Appendicectomy|appendix excision|appendicectomies|appendectomy|appendectomy procedures|APPENDECTOMY|appendectomy procedure|Primary appendectomy | Appendectomy |
C0024870 | Organized periodic procedures performed on large groups of people for the purpose of detecting disease. | Mass Screenings|mass screening|Screenings, Mass|Screening, Mass | Mass Screening |
C0199230 | Procedures performed on people to identify those who have NEOPLASMS or PRENEOPLASTIC CONDITIONS. | screening cancer|cancer detection early|Screening, Cancer|cancer screening|cancer early detection|Early Cancer Detection|Neoplasm screening|for cancer screening|Screening for cancer (procedure)|Cancer Screening for Patients|screening|Screening of Cancer|Screening for cancer|screen|screening for cancer|cancer screen|cancer screenings|Cancer Screening|neoplasms screening | Screening for cancer |
C0442864 | null | Littré hernia (disorder)|Littre's hernia | Littré hernia |
C0237401 | A person who lives alone or a single-family member who experiences a health-related problem. | individual|Individual|Individual (person) | Individual |
C0019699 | Development of neutralizing antibodies in individuals who have been exposed to the human immunodeficiency virus (HIV/HTLV-III/LAV). | hiv positive|Anti-HIV Positivity|HUMAN IMMUNODEFICIENCY VIRUS POSITIVE|HIV Antibody Positivity|HTLV-III Seropositivity|HTLV-3 antibody positive|Positivities, Anti-HIV|Positivities, HIV Antibody|HTLV-III Seropositivities|seropositive (AIDS test)|antigen positive AIDS test|HIV test positive|antibody positive AIDS test|SEROLOGY POSITIVE FOR HIV|Seropositivities, HIV|Human immunodeficiency virus positive (finding)|HIV seropositivity|HIV Seroconversion|HIV TEST POSITVE|HIV pos|Positivity, Anti-HIV|HTLV III Seropositivity|hiv +|HIV seropositive|hiv (+)|Anti-HIV Positivities|HTLV-III Seroconversions|Seroconversion, HTLV-III|Seropositivity, HIV|Seroconversions, AIDS|hiv pos|HIV Seroconversions|Anti HIV Positivity|Human Immunodeficiency Virus Positive|SEROPOSITIVE HTLV III|Seroconversion, HIV|HIV positives|HIV Seropositivity|HIV TEST POSITIVE|HIV Positivity|hiv+|Seropositivity, HTLV-III|Seropositivities, AIDS|Seropositivity, AIDS|HIV Seropositivities|positive HIV|HIV Positive|AIDS Seropositivities|Positivity, HIV Antibody|HTLV-III Seroconversion|HIV POSITIVE|Antibody Positivities, HIV|HIV seroconversion|HIV positive NOS|HIV+|SEROLOGY POSITIVE FOR HUMAN IMMUNODEFICIENCY VIRUS|Antibody Positivity, HIV|Human immunodeficiency virus positive|AIDS Seroconversions|HIV Antibody Positivities|AIDS Seropositivity|POSITIVE HIV ANTIBODY TEST|Seroconversion, AIDS|Seroconversions, HIV|Seroconversions, HTLV-III|AIDS Seroconversion|Human immunodeficiency virus (HIV) positive|HIV IMMUNOASSAY POSITIVE|HTLV III Seroconversion|Seropositivities, HTLV-III|seroconversion HIV|HIV positive | HIV Seropositivity |
C0521989 | null | associated symptoms|associated symptom|Associated symptom (finding)|Associated symptom | Associated symptom |
C0744979 | null | risk HIV|HIV risks | HIV risk |
C1369034 | An immunoglobulin (light chain specific) immunological test system is a device that consists of the reagents used to measure by immunochemical techniques both kappa and lambda types of light chain portions of immunoglobulin molecules in serum, other body fluids, and tissues. In some disease states, an excess of light chains are produced by the antibody-forming cells. These free light chains, unassociated with gamma globulin molecules, can be found in a patient's body fluids and tissues. Measurement of the various amounts of the different types of light chains aids in the diagnosis of multiple myeloma (cancer of antibody-forming cells), lymphocytic neoplasms (cancer of lymphoid tissue), Waldenstrom's macroglobulinemia (increased production of large immunoglobulins), and connective tissue diseases such as rheumatoid arthritis or systemic lupus erythematosus. | CYTOKERATINS | Cytokeratin test system |
C0019562 | An autosomal dominant disorder caused by mutations in a tumor suppressor gene. This syndrome is characterized by abnormal growth of small blood vessels leading to a host of neoplasms. They include HEMANGIOBLASTOMA in the RETINA; CEREBELLUM; and SPINAL CORD; PHEOCHROMOCYTOMA; pancreatic tumors; and renal cell carcinoma (see CARCINOMA, RENAL CELL). Common clinical signs include HYPERTENSION and neurological dysfunctions. | Hippel-Lindau Disease|Lindau' disease|VHL Syndromes|Familial Cerebelloretinal Angiomatosis|Lindau's disease|von Hippel-Lindau Disease|Cerebelloretinal Angiomatoses, Familial|Von Hippel-Lindau syndrome (disorder)|VHL|lindau von hippel disease|VHL Syndrome|hippel lindau syndrome von|Angiomatosis Retinae|von-hippel lindau disease|hippel lindaus syndrome von|Familial Cerebello Retinal Angiomatosis|VHL syndrome|lindau disease|Von Hippel Lindau Syndrome|Cerebello-Retinal Angiomatosis, Familial|Von Hippel-Lindau Syndrome|VON HIPPEL-LINDAU SYNDROME|von hippel lindau disease|von hippel-lindau disease|ANGIOPHAKOMATOSIS RETINAE ET CEREBELLI|hippel lindau disease|Angiomatoses, Familial Cerebello-Retinal|Cerebelloretinal Angiomatosis, Familial|hippel lindau von disease|Cerebroretinal Angiomatosis|Familial cerebello-retinal angiomatosis|Lindau Disease|von Hippel Lindau Disease|Angiomatoses, Familial Cerebelloretinal|von Hippel Lindau Syndrome|Hippel Lindau syndrome|Angiomatosis, Familial Cerebello-Retinal|VHL - von Hippel-Lindau syndrome|Von Hippel-Lindau Syndrome (VHL)|von Hippel-Lindau Syndrome|Cerebello-Retinal Angiomatoses, Familial|hippel-lindau disease|Hippel Lindau Disease|disease hippel-lindau von|von Hippel-Lindau syndrome|Lindau's Diseases|HEMANGIOBLASTOMATOSIS, CEREBELLORETINAL|lindau's disease|Lindaus Disease|VON HIPPEL-LINDAU DISEASE|Familial Cerebello-Retinal Angiomatoses|Familial Cerebello-Retinal Angiomatosis|Familial Cerebelloretinal Angiomatoses|hippel lindau syndrome|von hippel-lindau syndrome|von hippel lindau syndrome|Von Hippel-Lindau Disease|Von Hippel-Lindau syndrome|Lindau's Disease|disease hippel lindaus von|Cerebroretinal angiomatosis|Von Hippel Lindau syndrome|Angiomatosis, Familial Cerebelloretinal | Von Hippel-Lindau Syndrome |
C0162820 | A contact dermatitis due to allergic sensitization to various substances. These substances subsequently produce inflammatory reactions in the skin of those who have acquired hypersensitivity to them as a result of prior exposure. | Eczematous Dermatitides, Allergic|Dermatitis, Contact, Allergic|Contact Dermatitides, Allergic|allergic contact dermatitis|Allergic contact dermatitis (disorder)|Contact Dermatitis, Allergic|Dermatitides, Allergic Contact|Dermatitis, Allergic Eczematous|Contact allergy|Allergic Eczematous Dermatitides|Allergic Eczematous Dermatitis|dermatitis contact allergic|Allergic Contact Dermatitis|Dermatitides, Allergic Eczematous|ACD - Allergic contact dermatitis|contact allergic dermatitis|Allergic contact dermatitis|Eczematous Dermatitis, Allergic|Allergic Contact Dermatitides | Dermatitis, Allergic Contact |
C0028768 | An anxiety disorder characterized by recurrent, persistent obsessions or compulsions. Obsessions are the intrusive ideas, thoughts, or images that are experienced as senseless or repugnant. Compulsions are repetitive and seemingly purposeful behavior which the individual generally recognizes as senseless and from which the individual does not derive pleasure although it may provide a release from tension. | Obsessive Compulsive Disorder|Obsessive-Compulsive Neurosis|obsessive-compulsive psychoneurosis or reaction|Obsessive-Compulsive Disorders|Obsessive-compulsive disorder (disorder)|OCD - Obsessive-compulsive disorder|Neuroses, Obsessive-Compulsive|OBSESSIVE COMPULSIVE NEUROSIS|obsessive compulsive disorder (OCD)|REACTION OBSESSIVE-COMPULSIVE|Anancastic neurosis|Anankastic Personalities|Neurosis, Obsessive Compulsive|Obsessive compulsive neurosis|Disorders, Obsessive-Compulsive|obsessive-compulsive disorders|Neurosis, obsessive compulsive|Obsessive compulsive disorder, NOS|NEUROSIS, OBSESSIVE COMPULSIVE|OBSESSIVE-COMPULSIVE REACTION|anancastic neurosis|Anankastic Personality|obsessive-compulsive disorder|Obsessive-compulsive disorders|Obsessive Compulsive Neurosis|Obsessive-Compulsive Disorder|Disorder, Obsessive-Compulsive|obsessive compulsive neurosis|Obsessive-Compulsive Neuroses|Obsessive-compulsive disorder|OBSESSIVE-COMPULSIVE NEUROSIS|Anankastic neurosis|Obsessive compulsive disorder|obsessive-compulsive neurosis|OBSESSIVE COMPULSIVE DISORDER|Personality, Anankastic|Obsessive-compulsive neurosis|OBSESSIVE-COMPULSIVE DISORDER|Neurosis, Obsessive-Compulsive|obsessive compulsive disorder|OCD|Personalities, Anankastic | Obsessive-Compulsive Disorder |
C1263846 | A behavior disorder originating in childhood in which the essential features are signs of developmentally inappropriate inattention, impulsivity, and hyperactivity. Although most individuals have symptoms of both inattention and hyperactivity-impulsivity, one or the other pattern may be predominant. The disorder is more frequent in males than females. Onset is in childhood. Symptoms often attenuate during late adolescence although a minority experience the full complement of symptoms into mid-adulthood. (From DSM-V) | Deficit-Hyperactivity Disorders, Attention|Attention Deficit Disorders with Hyperactivity|Attention deficit disorder of childhood with hyperactivity|attention deficit(hyper) disorder|addh|attention deficit disorder with hyperactivity|Attention Deficit/Hyperactivity Disorder|Disorder, Attention Deficit-Hyperactivity|minimal brain dysfunction|Attention-Deficit Disorder, Predominantly Hyperactive-Impulsive Type|attention deficit hyperactivity disorder|ADD|attention deficit hyperactivity disorder (ADHD)|ADHD|ATTENTION DEFICIT-HYPERACTIVITY DISORDER|SYNDROME HYPERKINETIC|Hyperkinetic syndrome of childhood|Attention deficit disorder|Syndromes, Hyperkinetic|childhood hyperkinetic syndrome|ADDH|ADHD (attention deficit hyperactivity disorder)|Attention deficit hyperactivity disorder, hyperactive impulsive type|Unspecified hyperkinetic syndrome of childhood|hyperkinetic disorder|Attention deficit disorder with hyperactivity|Hyperkinetic syndrome NOS|Hyperactive child syndrome|ADHD - Attention deficit disorder with hyperactivity|Disorders, Attention Deficit-Hyperactivity|Hyperkinetic syndrome|hyperactivity disorder|Attention deficit-hyperactivity disorder (ADHD)|Overactive child syndrome|Attention deficit hyperactivity disorder|Attention deficit hyperactivity disorder (disorder)|HYPERACTIVITY OF CHILDHOOD|Hyperkinetic disorder|Attention Deficit Disorder with Hyperactivity|Hyperactivity Disorder NOS|Attention deficit/hyperactivity disorder|Unspecified hyperkinetic syndrome|Attention Deficit Hyperactivity Disorder|hyperkinetic syndrome|Attention Deficit Hyperactivity Disorders|Childhood attention deficit/hyperactivity disorder|Attention-deficit hyperactivity disorder|Attention-deficit/hyperactivity disorder|Hyperkinetic Syndrome|hyperactive child syndrome|Attention deficit hyperactivity disorder, predominantly hyperactive impulsive type|Attention deficits|HYPERKINETIC SYNDROME|Attention-deficit/hyperactivity disorder (ADHD)|Attention deficit hyperactivity disorder (ADHD)|attention deficit hyper disorder|Attention deficit-hyperactivity disorder|Hyperactivity Disorder, Predominantly Hyperactive-Impulsive Type|Attention-deficit hyperactivity disorder (ADHD)|Attention Deficit-Hyperactivity Disorder|Deficit-Hyperactivity Disorder, Attention|Attention deficit hyperkinetic disorder|Attention Deficit-Hyperactivity Disorders|Attention deficit hyperactivity disorder, predominantly hyperactive impulsive type (disorder)|disorder hyperactivity|attention deficits disorder hyper|Attention deficit|Attention deficit disorder with hyperactivity syndrome | Attention deficit hyperactivity disorder |
C0525045 | Those disorders that have a disturbance in mood as their predominant feature. | Disorders, Affective|disorder affect|Affective Disorder|affective mood disorders|mood disorders|Mood disorder, NOS|Affective disorders|affects disorder|Mood disorder (disorder)|Disorder, Mood|Mood disorders|Affective Disorders|Mood disorder|Disorder of affect|Mood Disorders|affective disorders|disorder mood|affective disorder|disorders mood|affect disorder|MOOD DISORDERS|affecive disorder nos|Disorder of affect, NOS|AFFECTIVE DISORDER|affecive disorder|UNSPECIFIED MOOD DISORDERS|Disorder, Affective|Affective disorder|affect disorders|mood disorder|Mood disorder NOS|Mood Disorder|mood disorder nos|Disorders, Mood | Mood Disorders |
C0278076 | Habitual, repeated, rapid contraction of certain muscles, resulting in stereotyped individualized actions that can be voluntarily suppressed for only brief periods. They often involve the face, vocal cords, neck, and less often the extremities. Examples include repetitive throat clearing, vocalizations, sniffing, pursing the lips, and excessive blinking. Tics tend to be aggravated by emotional stress. When frequent they may interfere with speech and INTERPERSONAL RELATIONS. Conditions which feature frequent and prominent tics as a primary manifestation of disease are referred to as TIC DISORDERS. (From Adams et al., Principles of Neurology, 6th ed, pp109-10) | Habit disorder|Spasm, Habit|Tic, behavioral|tics|behavioral tic|Chorea, Habit|Behavioural tic|Spasms, Habit|Habit spasm|tic|Habituation Spasm|Behavioral tic|Habit tic|Habit Spasm|Spasm, Habituation|habit spasm|Tic|Tics|Spasms, Habituation|Choreas, Habit|Habit tic (disorder)|Habituation Spasms|Habit Chorea|habit disorder|Habit Spasms|Habit Choreas | Behavioral tic |
C0040188 | Disorders characterized by recurrent TICS that may interfere with speech and other activities. Tics are sudden, rapid, nonrhythmic, stereotyped motor movements or vocalizations which may be exacerbated by stress and are generally attenuated during absorbing activities. Tic disorders are distinguished from conditions which feature other types of abnormal movements that may accompany another another condition. (From DSM-IV, 1994) | Tic disorders|Tic disorder, NOS|tic disorder|TIC DISORDER|tic disorders|Tic disorder (disorder)|disorders habit|Tic Disorders|Tic, NOS|tic disorder nos|tic|Tic disorder NOS|Tic|TIC DISORDERS|Tics|Tic (finding)|TIC|Tic disorder|habit disorder|TICS|Tic Disorder|Tic disorder, unspecified | Tic disorder |
C0679657 | null | cognitive techniques of affect and behavior change | cognitive technique |
C0001807 | Behavior which may be manifested by destructive and attacking action which is verbal or physical, by covert attitudes of hostility or by obstructionism. | aggressiveness|aggressive behavior|Aggressive behaviors|Aggressive behavior|aggressive behaviour|aggressive|aggressive and violent behavior|Aggression|Aggressive/violent behavior|Aggressive behavior (finding)|aggression|AGGRESSIVENESS|Aggressiveness|violent aggressive behavior|aggressive behaviors|aggressive behaviours|Aggressive behaviour|Aggressions | Aggressive behavior |
C0235952 | null | clostridium difficile diarrhoea|clostridium difficile diarrhea|DIARRHOEA, CLOSTRIDIUM DIFFICILE|Clostridium difficile diarrhea (disorder)|DIARRHEA, CLOSTRIDIUM DIFFICILE|Clostridium difficile diarrhoea | Clostridium difficile diarrhea |
C0017480 | A country in central Europe, bordering the Baltic Sea and the North Sea, between the Netherlands and Poland, south of Denmark. The capital is Berlin. | Germany|DE|germany|GERMANY|DEU|Germany (geographic location) | Germany |
C1273810 | null | null | nhs trust |
C1519427 | Denotes a person whose ancestry is in the countries of the Indian sub-continent, including India, Pakistan, Bangladesh, and Sri Lanka. | SOUTH ASIAN|South Asians | South Asian |
C1145677 | null | language ability|language skills|language skill|Language Ability|ability language|verbal ability|language aptitude | language ability |
C0391363 | null | AC2 (cyclase)|adenylyl cyclase type 2|adenylyl cyclase 2 | adenylyl cyclase 2 |
C0005497 | Biogenic amines having only one amine moiety. Included in this group are all natural monoamines formed by the enzymatic decarboxylation of natural amino acids. | Monoamines, Biogenic|biogenic monoamines | Biogenic Monoamines |
C0047556 | null | 3-methoxytyramine|3-O-METHYLDOPAMINE|3-methoxytyramine (substance)|methoxytyramine|Meta-o-methyldopamine|3 methoxydopamine | 3-methoxytyramine |
C0872271 | A class of drugs that act by inhibition of sodium influx through cell membranes. Blockade of sodium channels slows the rate and amplitude of initial rapid depolarization, reduces cell excitability, and reduces conduction velocity. | Substance with sodium channel blocker mechanism of action (substance)|Sodium Channel Blockers|Channel Blockers, Sodium|Sodium channel blocker|sodium channel blockers|Channel Inhibitors, Sodium|sodium channel blocker|Sodium Channel Inhibitors|Inhibitors, Sodium Channel | Sodium Channel Blockers |
C0035973 | A hard, brittle, grayish-white rare earth metal with an atomic symbol Ru, atomic number 44, and atomic weight 101.07. It is used as a catalyst and hardener for PLATINUM and PALLADIUM. | ruthenium|Ruthenium, NOS|Ru element|Ruthenium (substance)|RUTHENIUM|Ruthenium | ruthenium |
C0019941 | An enzyme isolated from horseradish which is able to act as an antigen. It is frequently used as a histochemical tracer for light and electron microscopy. Its antigenicity has permitted its use as a combined antigen and marker in experimental immunology. | Horseradish peroxidase (substance)|Horseradish peroxidase|horseradish peroxidase|horseradish peroxidase (HRP)|HRP|Horseradish Peroxidase|Peroxidase, Horseradish|hrp | Horseradish Peroxidase |
C1441554 | null | Direct assay technique|Direct assay technique (qualifier value) | Direct assay |
C1522485 | A substance that is identifiable by virtue of its radioactive signature, color, or other distinguishing physical property, such as a dye, radioactive isotope, or inert chemical, that is introduced into a biological or mechanical system and can be followed through the course of a process, providing information on the pattern of events in the process or on the redistribution of the parts, elements, or events involved. | Label|tracers|Tagged|Tag|tracer|Tracer|Reporter|Labeled | Tracer |
C0761062 | null | poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) | PEO-PPO-PEO |
C0005498 | Biogenic amines having more than one amine group. These are long-chain aliphatic compounds that contain multiple amino and/or imino groups. Because of the linear arrangement of positive charge on these molecules, polyamines bind electrostatically to ribosomes, DNA, and RNA. | Polyamines, Biogenic|biogenic polyamines | Biogenic Polyamines |
C1149313 | Interacting selectively and non-covalently with an immunoglobulin of an IgG isotype. [GOC:add, ISBN:0781735149] | null | IgG binding |
C0075278 | A 60-kDa extracellular protein of Streptomyces avidinii with four high-affinity biotin binding sites. Unlike AVIDIN, streptavidin has a near neutral isoelectric point and is free of carbohydrate side chains. | streptavidin|Streptavidin|Strepavidin|Streptavidin (substance) | Streptavidin |
C0007449 | Positively charged atoms, radicals or group of atoms with a valence of plus 1, which travel to the cathode or negative pole during electrolysis. | Monovalent cations|Monovalent Cations | Cations, Monovalent |
C0132555 | Expressed in various cell types, Nitric Oxide Synthases (NOS Family) are constitutive or inducible calcium/calmodulin stimulated homodimers stabilized by BH4 that bind FAD and FMN cofactors, generally contain a flavodoxin-like domain, and synthesize reactive free radical nitric oxide messenger from L-arginine. NO can act as a neurotransmitter and has antimicrobial and antitumoral activities in macrophages. IL12 requires NOS to stimulate tyrosine-phosphorylation of STAT4 by TYK2 in NK cytotoxicity. Vascular NO (endothelia) inhibits muscle contraction through a cGMP pathway, inhibits platelet aggregation, and mediates VEGF-induced angiogenesis. Endothelial AKT phosphorylates and enhances NOS activity. Potentially influencing energy balance, NO can trigger cGMP-dependent mitochondrial biogenesis mediated by induction of the master regulator PPARGC1. (NCI) | nitric oxide synthase|nitric oxide synthetase|NOS|NO Synthase|synthase|Nitric-oxide synthase|Synthase, Nitric Oxide|Oxide Synthase, Nitric|Nitric-oxide synthase (substance)|Endothelium-derived relaxing factor synthase|nitric oxide synthases|NOS Family|Nitric Oxide Synthetase|Nitric Oxide Synthase Family|Nitric-Oxide Synthetase|Nitric Oxide Synthase|NADPH-Diaphorase|NO synthase|EC 1.14.13.39|Endothelium-derived relaxation factor-forming enzyme|L-Arginine,NADPH:oxygen oxidoreductase (nitric-oxide-forming)|Nitric-Oxide Synthase | Nitric Oxide Synthase |
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