ENTITY
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DEFINITION
stringlengths
3
8.47k
ALIASES
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2
13.6k
NAME
stringlengths
2
1.98k
C0442010
null
Buccal (qualifier value)|buccal|Buccal
Buccal
C0063817
A contrast medium.
Product containing iopromide (medicinal product)|Iopromide-containing product|N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-[(methoxyacetyl)amino]-N-methylisophthalamide|lopromid|Iopromide|Iopromida|IOPROMIDE|N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-(2-methoxyacetamido)-N-methylisophthalamide|Iopromide (substance)|iopromid|iopromide
iopromide
C0025556
A group of elements that include SCANDIUM; YTTRIUM; and the LANTHANOID SERIES ELEMENTS. Historically, the rare earth metals got their name from the fact that they were never found in their pure elemental form, but as an oxide. In addition they were very difficult to purify. They are not truly rare and comprise about 25% of the metals in the earth's crust.
Rare Earth Metals|rare earth elements|rare earth element|Rare earth metals|rare earths|Rare earth metal compounds|Earths, Rare|Earth Metals, Rare|rare earth
Metals, Rare Earth
C0016352
An analytical method for detecting and measuring FLUORESCENCE in compounds or targets such as cells, proteins, or nucleotides, or targets previously labeled with FLUORESCENCE AGENTS.
fluorimetry|Fluorimetry|Analysis, Fluorometric|fluorometry|FLUORIMETRY|Fluorometric Analysis
Fluorometry
C0528249
null
HumaLOG|humalog|Humalog
Humalog
C0010357
Serological reactions in which an antiserum against one antigen reacts with a non-identical but closely related antigen.
Cross Reactions|Cross-reactive|Reactions, Cross|Cross-reaction|cross reaction|Crosstalk|Cross Reactivity|Cross Reaction|cross reactions|Reaction, Cross
Cross Reactions
C0751973
The protein complement of an organism coded for by its genome.
Proteome|proteome|Proteomes
Proteome
C0024742
A hexose or fermentable monosaccharide and isomer of glucose from manna, the ash Fraxinus ornus and related plants. (From Grant & Hackh's Chemical Dictionary, 5th ed & Random House Unabridged Dictionary, 2d ed)
D-Mannose|Mannose|D-mannose|d-mannose|MANNOSE|D Mannose|Mannose, D-|Mannose (substance)|Mannopyranoside|MANNOSE, D-|Carubinose|Seminose|Mannopyranose|d mannose|mannose
mannose
C0066072
null
Methacrylic acid|Methacrylic Acid|2-methylpropenoic acid|methacrylic acid|METHACRYLIC ACID|Methacrylic acid (substance)|2-Methylpropenoic acid|2-Methyl-2-propenoic Acid
methacrylic acid
C0077193
null
TMPTMA|trimethylol propane trimethacrylate
trimethylolpropane trimethacrylate
C0009077
A semi-synthetic antibiotic that is a chlorinated derivative of OXACILLIN.
Cloxacillin|cloxacillin|Product containing cloxacillin (medicinal product)|CLOXACILLIN|(2S,5R,6R)-6-({[3-(2-chlorophenyl)-5-methylisoxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid|Chloroxacillin|6-(3-(o-chlorophenyl)-5-methyl-4-isoxazolecarboxamido)penicillanic acid|Cloxacilina|Cloxacilline|Cloxacillin (substance)|(3-(o-chlorophenyl)-5-methyl-4-isoxazolyl)penicillin|Cloxacillinum|4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((3-(2-chlorophenyl)-5-methyl-4-isoxazolyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, (2S-(2alpha,5alpha,6beta))-|Cloxacillin-containing product
cloxacillin
C0012093
One of the PENICILLINS which is resistant to PENICILLINASE.
4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, (2S-(2alpha,5alpha,6beta))-|Dichloroxacillin|Dicloxacilline|dicloxacillin|Dicloxacillin-containing product|DICLOXACILLIN|Dicloxacillin|Product containing dicloxacillin (medicinal product)|Dicloxacillina|Dicloxacillin (substance)|Dicloxaciclin|(2S,5R,6R)-6-({[3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid|3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolylpenicillin|Dicloxacilina|Dicloxacillinum|Dicloxacycline
dicloxacillin
C0002645
A broad-spectrum semisynthetic antibiotic similar to AMPICILLIN except that its resistance to gastric acid permits higher serum levels with oral administration.
Amox|AMOXICILLIN|amoxicillin|Amoxicillinum|amoxycillin|Amoxicillin-containing product|Amoxicilline|Amoxicillin (substance)|Amoxicillin|p-Hydroxyampicillin|AMOX|Hydroxyampicillin|Product containing amoxicillin (medicinal product)|α-amino-p-hydroxybenzylpenicillin|6-(p-hydroxy-α-aminophenylacetamido)penicillanic acid|Amoxicilina|AX|Amoxycillin
amoxicillin
C0030840
A broad-spectrum penicillin antibiotic used orally in the treatment of mild to moderate infections by susceptible gram-positive organisms.
fenoxymethylpenicillin|6-phenoxyacetamidopenicillanic acid|penicillins v|Phenoxymethyl Penicillin|Phenoxymethylenepenicillinic acid|Phenoxymethylpenicillin-containing product|Phénoxyméthylpénicilline|(2S,5R,6R)-3,3-DIMETHYL-7-OXO-6-(2-PHENOXYACETAMIDO)-4-THIA-1- AZABICYCLO(3.2.0)HEPTANE-2-CARBOXYLIC ACID|Phenoxomethylpenicillin|phenoxymethylpenicillin|PENICILLIN V|Phenoxymethyl penicillin|phenoxymethyl penicillin|Penicillin V-containing product|Penicillin Phenoxymethyl|4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-((phenoxyacetyl)amino)-, (2S-(2alpha,5alpha,6beta))-|penicillin v|Phenoxymethylpenicillin (substance)|Penicillin, Phenoxymethyl|Fenoxymethylpenicillin|(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid|Phenoxymethylpenicillinum|Penicillin V|Fenoximetilpenicilina|Product containing phenoxymethylpenicillin (medicinal product)|Penicillin V, NOS|PV|Phenoxymethylpenicillin
penicillin V
C0051653
null
6-aminopenicillamine acid|6-aminopenicillanic acid|6-APA cpd
aminopenicillanic acid
C0007737
Cephalosporin antibiotic, partly plasma-bound, that is effective against gram-negative and gram-positive organisms.
Cefapirine|Cephapirine|cefapirin|Cefapirina|Cefapirinum|Product containing cefapirin (medicinal product)|Cephapirin-containing product|Cefapirin-containing product|CEPR|Cefaprin|Cephapirin|Cefapirin (substance)|(6R,7R)-3-(acetoxymethyl)-8-oxo-7-{[(pyridin-4-ylsulfanyl)acetyl]amino}-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid|5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 3-((acetyloxy)methyl)-8-oxo-7-(((4-pyridinylthio)acetyl)amino)-, (6R-trans)-|Cefapirin|CEPHAPIRIN|cephapirin
cephapirin
C0039644
A naphthacene antibiotic that inhibits AMINO ACYL TRNA binding during protein synthesis.
(4S,4aS,5aS,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide|Tetracyclin|Tetracycline|tetracycline|Tetrazyklin|Tétracycline|Tetracycline (substance)|Tsiklomitsin|Tetracycline-containing product|TCN|2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S-(4alpha,4aalpha,5aalpha,6beta,12aalpha))-|Tetracycline, NOS|TETRACYCLINE|Tetracyclinum|Product containing tetracycline (medicinal product)|4-(Dimethylamino)-1,4,4A,5,5A,6,11,12A-Octahydro-3,6,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-2-Naphthacenecarboxamide
tetracycline
C0723176
null
sfc
SFC (Brand Name)
C1138408
Fullerene-like nanostructures that consist of graphene cylinders. The ends of the construct are closed with pentagonal-shaped rings.
Nanotube, Carbon|Carbon Nanotube|carbon nanotube|Buckytube|Carbon Nanotubes|carbon nanotubes|Buckytubes
Nanotubes, Carbon
C0074745
null
periodate ion|periodic acid (HIO4), sodium salt|periodate
metaperiodate
C0012873
Enzymes that are part of the restriction-modification systems. They are responsible for producing a species-characteristic methylation pattern, on either adenine or cytosine residues, in a specific short base sequence in the host cell's own DNA. This methylated sequence will occur many times in the host-cell DNA and remain intact for the lifetime of the cell. Any DNA from another species which gains entry into a living cell and lacks the characteristic methylation pattern will be recognized by the restriction endonucleases of similar specificity and destroyed by cleavage. Most have been studied in bacterial systems, but a few have been found in eukaryotic organisms.
Modification Methylases, DNA|DNA Modification Methylases|Modification Methylases|DNA Methyltransferase|DNA Modification Methyltransferases|Modification Methyltransferases, DNA|DNA-Methyltransferase|DNA MTase|DNA methyltransferase|Site-Specific DNA-methyltransferase|Dnmt|Methylases, Modification|Methyltransferases, DNA Modification|Methylases, DNA Modification|DNA Modification Methylase|EC 2.1.1.113|DNA methylase
DNA Modification Methylases
C1328819
A molecule with a low molecular weight that is not determined by a genome sequence.
small molecule|Small Molecule
Small Molecule
C0025677
An antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of TETRAHYDROFOLATE DEHYDROGENASE and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA.
4-amino-10-methylfolic acid|4-Amino-4-deoxy-10-methylpteroyl-L-glutamic Acid|Methotrexate Methylaminopterin|MTX|alpha-methopterin|methylaminopterin|Methotrexate (substance)|METHOTREXATE|N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid|Product containing methotrexate (medicinal product)|mtx|L-Glutamic acid, N-(4-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-|4-amino-4-deoxy-10-methylpteroyl-L-glutamic acid|N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic Acid|Amethopterin|Methotrexate|amethopterin|4-amino-N(10)-methylpteroylglutamic acid|Methotrexatum|methotrexate|Methotrexat|Alpha-Methopterin|Methotrexate-containing product|Metotrexato|MTX - methotrexate|4-Amino-10-methylfolic Acid|Méthotrexate|methotrexate methylaminopterin
methotrexate
C0040077
A nucleoside in which THYMINE is linked to DEOXYRIBOSE.
2'-thymidine|thymidine|dThd|thymidin|Deoxyribosylthymine|deoxyribosylthymine|Thymidine (substance)|dT|TDR|Thymine deoxyriboside|Thymidine|THYMIDINE|Thymidin|Thymine 2'-deoxyriboside|2'-deoxy-5-methyluridine
thymidine
C1563732
A polymeric molecule which has a highly-branched, three-dimensional architecture. Dendrimers are synthesized from monomers and new branches are added in discrete steps to form a tree-like architecture. A high level of synthetic control is achieved through step-wise reactions and purification at each step to regulate the size, architecture, functionality and monodispersity of the molecules. These polymers have desirable pharmacokinetic properties and a polyvalent array of surface groups that make them potential drug delivery vesicles.
Dendrimer|Dendrimers|Dendritic Compound|Dendrons|Polymers, Dendritic|Dendritic Polymers|Dendritic Compounds|Polymer, Dendritic|Cascade Molecule|Dendritic Polymer|Compound, Dendritic
Dendrimers
C0054015
A recombinant version of the cardiac neurohormone, human B-type natriuretic peptide (hBNP) produced by the ventricular myocardium. Nesiritide binds to natriuretic peptide receptors on vascular smooth muscle and endothelial cells, through which it triggers guanylate cyclase dependent signal transduction resulting in increase of intracellular concentrations of cGMP. This leads to smooth muscle cell relaxation causing arterial and venous dilatation.
BNP-32|Brain natriuretic peptide|Natriuretic factor, brain|Brain Natriuretic Peptide 32|BNP 32|b-type natriuretic peptide|Brain natriuretic peptide 32|B-Type Natriuretic Peptide|Nesiritide-containing product|BNP(1-32)|Natriuretic Peptide Type-B|Natriuretic Peptide, Brain|Natriuretic factor-32|Natriuretic Peptide Type B|Natriuretic Peptide-32, Brain|Brain Natriuretic Peptide|B-type natriuretic peptide|b type natriuretic peptides|Natriuretic Factor 32|Natriuretic peptide B Type|nesiritide|Human brain natriuretic factor-32|Product containing nesiritide (medicinal product)|1,2-Dithia-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50-hexadecaazacyclotripentacontane, Cyclic Peptide Derivative|brain natriuretic peptide|Peptide-32, Brain Natriuretic|Natriuretic Factor-32|Type B Natriuretic Peptide|Natriuretic Peptide, B-Type|Type-B Natriuretic Peptide|L-Histidine, L-seryl-L-prolyl-L-lysyl-L-methionyl-L-valyl-L-glutaminylglycyl-L-serylglycyl-L-cysteinyl-L-phenylalanylglycyl-L-arginyl-L-lysyl-L-methionyl-L-alpha-aspartyl-L-arginyl-L-isoleucyl-L-seryl-L-seryl-L-seryl-L-serylglycyl-L-leucylglycyl-L-cysteinyl-L-lysyl-L-valyl-L-leucyl-L-arginyl-L-arginyl-, Cyclic (10-26)-disulfide|BNP Gene Product|Brain Natriuretic Peptide-32|Brain natriuretic peptide (substance)|NESIRITIDE|brain natriuretic peptides|Natriuretic Peptide, Type-B|b type natriuretic peptide|Human Brain Natriuretic Factor-32|Peptide, Brain Natriuretic|Nesiritide|BNP|Nesiritide (substance)|Human B-type natriuretic peptide|brain natriuretic factor|type b natriuretic peptide
nesiritide
C0597049
Substances secreted by neurons into the blood, CNS, or intercellular space.
neurohormones|THDOC|Neurohormones|neurohormone
Neurohormones
C0054015
A recombinant version of the cardiac neurohormone, human B-type natriuretic peptide (hBNP) produced by the ventricular myocardium. Nesiritide binds to natriuretic peptide receptors on vascular smooth muscle and endothelial cells, through which it triggers guanylate cyclase dependent signal transduction resulting in increase of intracellular concentrations of cGMP. This leads to smooth muscle cell relaxation causing arterial and venous dilatation.
BNP-32|Brain natriuretic peptide|Natriuretic factor, brain|Brain Natriuretic Peptide 32|BNP 32|b-type natriuretic peptide|Brain natriuretic peptide 32|B-Type Natriuretic Peptide|Nesiritide-containing product|BNP(1-32)|Natriuretic Peptide Type-B|Natriuretic Peptide, Brain|Natriuretic factor-32|Natriuretic Peptide Type B|Natriuretic Peptide-32, Brain|Brain Natriuretic Peptide|B-type natriuretic peptide|b type natriuretic peptides|Natriuretic Factor 32|Natriuretic peptide B Type|nesiritide|Human brain natriuretic factor-32|Product containing nesiritide (medicinal product)|1,2-Dithia-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50-hexadecaazacyclotripentacontane, Cyclic Peptide Derivative|brain natriuretic peptide|Peptide-32, Brain Natriuretic|Natriuretic Factor-32|Type B Natriuretic Peptide|Natriuretic Peptide, B-Type|Type-B Natriuretic Peptide|L-Histidine, L-seryl-L-prolyl-L-lysyl-L-methionyl-L-valyl-L-glutaminylglycyl-L-serylglycyl-L-cysteinyl-L-phenylalanylglycyl-L-arginyl-L-lysyl-L-methionyl-L-alpha-aspartyl-L-arginyl-L-isoleucyl-L-seryl-L-seryl-L-seryl-L-serylglycyl-L-leucylglycyl-L-cysteinyl-L-lysyl-L-valyl-L-leucyl-L-arginyl-L-arginyl-, Cyclic (10-26)-disulfide|BNP Gene Product|Brain Natriuretic Peptide-32|Brain natriuretic peptide (substance)|NESIRITIDE|brain natriuretic peptides|Natriuretic Peptide, Type-B|b type natriuretic peptide|Human Brain Natriuretic Factor-32|Peptide, Brain Natriuretic|Nesiritide|BNP|Nesiritide (substance)|Human B-type natriuretic peptide|brain natriuretic factor|type b natriuretic peptide
nesiritide
C0264716
null
chronic heart failure|Chronic heart failure (disorder)|Heart failure, chronic|chronic failure heart|chronic cardiac failure|Chronic heart failure
Chronic heart failure
C0041236
A serine endopeptidase that is formed from TRYPSINOGEN in the pancreas. It is converted into its active form by ENTEROPEPTIDASE in the small intestine. It catalyzes hydrolysis of the carboxyl group of either arginine or lysine. EC 3.4.21.4.
Trypsin|Tripsina|Tripcellim|alpha- and beta-Trypsin|Alpha- and beta-trypsin|TRYPSIN, UNSPECIFIED FORM|trypsin|Trypsin (substance)|TRYPSIN
trypsin
C0006007
Inorganic or organic salts and esters of boric acid.
borates|Borate|borated|Borate salt|Borates|borate|Borate (substance)
Borates
C0670626
null
laminin 8|laminin-8|alpha4beta1gamma1-laminin|laminin-(alpha4beta1gamma1)
laminin-8
C0040669
The uptake of naked or purified DNA by CELLS, usually meaning the process as it occurs in eukaryotic cells. It is analogous to bacterial transformation (TRANSFORMATION, BACTERIAL) and both are routinely employed in GENE TRANSFER TECHNIQUES.
Transfections|transfection|Transfection
Transfection
C0086964
Genus in the grass family (Poaceae) including well known species Secale cereale (rye).
Secale|Secale (organism)|Rye|secale|Secale, NOS
Secale
C0086964
Genus in the grass family (Poaceae) including well known species Secale cereale (rye).
Secale|Secale (organism)|Rye|secale|Secale, NOS
Secale
C0052350
A consensus tripeptide that is recognized by and for binding to proteins of the integrin family, including many cell adhesion molecules. The one-letter codes for arginine - glycine - aspartic acid. This motif can be found in proteins of the extracellular matrix and it is recognized by different members of the integrin family. The structure of the tenth type III module of fibronectin has shown that the RGD motif lies on a flexible loop.
arginyl-glycyl-aspartic acid|RGD (sequence)|RGD Motif|RGD|RGD (peptide)|RGD peptide|Arg-Gly-Asp|RGD Cell Adhesion Domain|RGD Peptide|RGD Tripeptide Sequence|RGD tripeptide|RGD Domain|Arginine-Glycine-Aspartic Acid Cell Adhesion Domain
arginyl-glycyl-aspartic acid
C0026794
A basic enzyme that is present in saliva, tears, egg white, and many animal fluids. It functions as an antibacterial agent. The enzyme catalyzes the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrin. EC 3.2.1.17.
lysozymes|Peptidoglycan N-acetylmuramoylhydrolase|lysosyme|Glycanhydrolase, N-Acetylmuramide|Lysozyme (substance)|Muramidase (Lysozyme)|N Acetylmuramide Glycanhydrolase|Muramidase|Lysozyme|lysozyme|IMMUNOCHEMICAL, LYSOZYME (MURAMIDASE)|muramidase|N-Acetylmuramide Glycanhydrolase
muramidase
C0244713
A non-glycosylated form of interferon beta-1 that has a serine at position 17. It is used in the treatment of both RELAPSING-REMITTING MULTIPLE SCLEROSIS and CHRONIC PROGRESSIVE MULTIPLE SCLEROSIS.
interferon beta-1b|Interferon Beta, Ser(17)|Product containing interferon beta-1b (medicinal product)|Ser(17) IFN-beta|Interferon beta-1b (substance)|Interferon beta 1b|1b beta interferon|Interferon beta-1b-containing product|Beta-ser-interferon|interferon beta 1b|Beta-IFN-1b|Recombinant interferon beta-1b|Interferon-beta-1b|Interferon Beta-1B|Serine(17) Interferon Beta|IFN-Beta Ser|Interferon beta-1b|INTERFERON BETA-1B|Interferon Beta-1b|Interferon Beta, Serine(17)
interferon beta-1b
C0597717
A type of FLUORESCENCE SPECTROSCOPY using two FLUORESCENT DYES with overlapping emission and absorption spectra, which is used to indicate proximity of labeled molecules. This technique is useful for studying interactions of molecules and PROTEIN FOLDING.
fluorescence resonance energy transfer|Forster Resonance Energy Transfer|FRET
Fluorescence Resonance Energy Transfer
C1148846
Interacting selectively and non-covalently with an RNA molecule or a portion thereof. [GOC:jl, GOC:mah]
RNA binding
RNA Binding
C1335533
A fragment of a protein, which may be a diagnostic or prognostic factor and used as a biomarker. (NCI)
null
Protein Fragment
C0525032
System established by the World Health Organization and the International Committee on Thrombosis and Hemostasis for monitoring and reporting blood coagulation tests. Under this system, results are standardized using the International Sensitivity Index for the particular test reagent/instrument combination used.
International normalized ratio|internationalised ratio|International normalized ratio (observable entity)|International Normalized Ratio|INR (International normalized ratio)|Normalized Ratio, International|Ratio, International Normalized|International normalized ratio (qualifier value)|international normalizing ratio|international normalized ratio (INR)|International Normalized Ratios|INR (International normalised ratio)|Ratios, International Normalized|international normalize ratio|international normalized ratio|INR|international normalising ratio|International normalised ratio|international normalized ratios|INR - Internationalised ratio|Normalized Ratios, International|international normalised ratio|Internationalised ratio|bcr
International Normalized Ratio
C0038623
A subclass of IMIDES with the general structure of pyrrolidinedione. They are prepared by the distillation of ammonium succinate. They are sweet-tasting compounds that are used as chemical intermediates and plant growth stimulants.
Succinimide-containing product|Succinimide (substance)|Product containing succinimide (product)|Butanimides|Pyrrolidinediones|succinimide|Succinimides|succinimides|Succinimide|SUCCINIMIDES
Succinimides
C0529073
null
null
CM-DiI
C0028953
Polymers made up of a few (2-20) nucleotides. In molecular genetics, they refer to a short sequence synthesized to match a region where a mutation is known to occur, and then used as a probe (OLIGONUCLEOTIDE PROBES). (Dorland, 28th ed)
oligonucleotide|Oligonucleotide (substance)|Oligonucleotide, NOS|Oligonucleotides|oligonucleotides|Oligonucleotide|Oligo
Oligonucleotides
C0010656
A family of intracellular CYSTEINE ENDOPEPTIDASES that play a role in regulating INFLAMMATION and APOPTOSIS. They specifically cleave peptides at a CYSTEINE amino acid that follows an ASPARTIC ACID residue. Caspases are activated by proteolytic cleavage of a precursor form to yield large and small subunits that form the enzyme. Since the cleavage site within precursors matches the specificity of caspases, sequential activation of precursors by activated caspases can occur.
caspase|Cysteine-aspartic Protease|cysteine endopeptidase|Peptidase Family C14|Cysteine-Dependent Aspartate-Directed Protease|ICE-like protease|Caspases|ICE-like proteases|Caspase|Cell-Death Protease|cystein protease|cystein proteinase
caspase
C0036248
A compound that contains a reduced purine ring system but is not biosynthetically related to the purine alkaloids. It is a poison found in certain edible mollusks at certain times; elaborated by GONYAULAX and consumed by mollusks, fishes, etc. without ill effects. It is neurotoxic and causes RESPIRATORY PARALYSIS and other effects in MAMMALS, known as paralytic SHELLFISH poisoning.
Gonyaulax Toxin|Saxitoxin|stx|Toxin, Gonyaulax|Saxitoxin (substance)|saxitoxin|saxitoxins|1H,10H-Pyrrolo(1,2-c)purine-10,10-diol, 2,6-diamino-4-(((aminocarbonyl)oxy)methyl)-3a,4,8,9-tetrahydro-, (3aS-(3aalpha,4alpha,10aR*))-|Mitilotoxin|Saxitonin|STX
Saxitoxin
C0242821
The human being as a non-anatomical and non-zoological entity. The emphasis is on the philosophical or artistic treatment of the human being, and includes lay and social attitudes toward the body in history. (From J. Cassedy, NLM History of Medicine Division)
bodies|Human Figures|Human Figure|body|Human body|human body|Human Body|Bodies, Human|Human Bodies|body human|Body, Human|Figure, Human|Figures, Human
Human body
C0072162
null
PDTA
propanoldiaminetetracetic acid
C0044873
null
null
15-crown-5
C0085101
Radiotherapy where cytotoxic radionuclides are linked to antibodies in order to deliver toxins directly to tumor targets. Therapy with targeted radiation rather than antibody-targeted toxins (IMMUNOTOXINS) has the advantage that adjacent tumor cells, which lack the appropriate antigenic determinants, can be destroyed by radiation cross-fire. Radioimmunotherapy is sometimes called targeted radiotherapy, but this latter term can also refer to radionuclides linked to non-immune molecules (see RADIOTHERAPY).
Immunoradiotherapy|Radioimmunotherapies|Immunoradiotherapies|Radioimmunotherapy|radioimmunotherapeutics|radioimmunotherapy|Radioimmunotherapy (procedure)|Immunotherapy, Cancer, Radioisotope
Radioimmunotherapy
C0002508
A group of compounds derived from ammonia by substituting organic radicals for the hydrogens. (From Grant & Hackh's Chemical Dictionary, 5th ed)
Amines|amines|AMINES|Amine (substance)|amine|Amine, NOS|Amine|NH2
Amines
C0017906
Carbohydrates covalently linked to a nonsugar moiety (lipids or proteins). The major glycoconjugates are glycoproteins, glycopeptides, peptidoglycans, glycolipids, and lipopolysaccharides. (From Biochemical Nomenclature and Related Documents, 2d ed; From Principles of Biochemistry, 2d ed)
Glycoconjugates|glycoconjugates|Glycoconjugate|glycoconjugate
Glycoconjugates
C0019046
The oxygen-carrying proteins of ERYTHROCYTES. They are found in all vertebrates and some invertebrates. The number of globin subunits in the hemoglobin quaternary structure differs between species. Structures range from monomeric to a variety of multimeric arrangements.
Hemoglobin, NOS|Hemoglobins|Hb - Hemoglobin|HEMOGLOBINS|hemoglobin (Hb)|Haemoglobin|haemoglobin|Hemoglobin (substance)|Hgb|hemoglobin|Hb - Haemoglobin|Haemoglobin, NOS|HGB - Haemoglobin|Hemoglobin|Hb|HGB - Hemoglobin
Hemoglobin
C0035525
A nucleoside antimetabolite antiviral agent that blocks nucleic acid synthesis and is used against both RNA and DNA viruses.
RTCA|1-.beta.-D-Ribofuranosyl-1H-1,2, 4-triazole-3-carboxamide|Ribavirin (substance)|RIBA|1H-1,2,4-Triazole-3-carboxamide, 1-beta-D-ribofuranosyl-|1-beta-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide|Ribavirina|1-Beta-D-ribofuranosyl-1,2,4-triazolo-3-carboxamide|1-beta-D-ribofuranosyl-1,2,4-triazolo-3-carboxamide|Ribavirin|1-beta-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide|ribovirin|Ribavirin-containing product|Product containing ribavirin (medicinal product)|RBV|Ribavirine|1-Beta-D-ribofuranosyl-1H-1,2,4-triazole-3-carboxamide|1-beta-D-ribofuranosyl-1H-1,2,4-triazole-3-carboxamide|Ribavrin|Tribavirin|RIBAVIRIN|Ribovirin|ribavirin|Ribavirinum
ribavirin
C0021747
Proteins secreted by vertebrate cells in response to a wide variety of inducers. They confer resistance against many different viruses, inhibit proliferation of normal and malignant cells, impede multiplication of intracellular parasites, enhance macrophage and granulocyte phagocytosis, augment natural killer cell activity, and show several other immunomodulatory functions.
Product containing interferon (product)|Interferon|interferons|Interferons|Interferon-containing product|interferon|Interferon (substance)|INTERFERON|IFN
Interferons
C0007061
Hemoglobin where the heme group has formed a stable complex with carbon monoxide (CO). This complex is produced after CO has been inhaled or as a byproduct of hemoglobin, protoporphyrin or dichloromethane catabolism. The heme-CO complex is approximately 200 times more stable than heme-oxygen complexes. Thus, high levels of carboxyhemoglobin in the circulation can lead to tissue hypoxia and death.
Carbonylhemoglobin|Carboxyhemoglobin|Carboxyhaemoglobin|carboxyhemoglobin|HbCO - Carboxyhemoglobin|Hemoglobins, carbonyl-|HbCO - Carboxyhaemoglobin|Carbonyl hemoglobin|Carbon monoxide haemoglobin|Carbomonoxyhemoglobin|hemoglobin carbon monoxide|COHb|Carbon monoxide hemoglobin|Carbonmonoxyhemoglobin|carboxyhemoglobins|Carboxyhemoglobin (substance)|Carbonyl haemoglobin|carboxyhaemoglobin
Carboxyhemoglobin
C0000820
Abortion induced to save the life or health of a pregnant woman. (From Dorland, 28th ed)
Therapeutic Abortion Procedure|Therapeutic abortion|Therapeutic abortion procedure (procedure)|Therapeutic Abortions|therapeutic abortion|therapeutic abortions|abortion therapeutic|Abortion, Therapeutic|Abortion, therapeutic|Therapeutic Abortion|abortions therapeutic|Therapeutic abortion procedure, NOS|Therapeutic abortion procedure|Abortions, Therapeutic|Therapeutic termination of pregnancy procedure|Therapeutic abortion NOS
Therapeutic abortion (procedure)
C0596973
A chemical subunit that can undergo polymerization by bonding to other subunits.
monomers|monomer
Monomer
C0009924
Substances used to allow enhanced visualization of tissues.
Contrast media|Agents, Contrast|Contrast Agents|contrast material|contrast agents|radiographic contrast media|Contrast Agent|Contrast Materials|Contrast media (product)|Contrast Drugs|Contrast Material|Contrast|Agent, Contrast|Contrast media (substance)|Media, Contrast|radiographic contrast material|Material, Contrast|Materials, Contrast|Contrast Media|Contrast Medium|contrast media|contrast agent|CONTRAST MEDIA|Contrast media, NOS
Contrast Media
C1327806
A technique incorporating MALDI that uses ultraviolet absorbing organic molecules (matrix) to transfer energy from a LASERS to an analyte for desorption and ionization. It is useful for PROTEIN ARRAY ANALYSIS.
SELDI-TOF-MS|surface-enhanced laser desorption/ionization-time of flight mass spectrometry|SELDI-TOF|Surface-Enhanced Laser Desorption/Ionization-Time of Flight Mass Spectrometry
Surface Enhanced Laser Desorption Ionization Mass Spectrometry
C0230664
null
Membrane receptor|Membrane receptor (cell structure)|membrane receptors|membrane receptor
Membrane receptor
C0439857
The psychological or physiological need to take a substance in order to experience its effects or to avoid the effects of its absence.
Patient dependence on (contextual qualifier)|Patient dependence on (contextual qualifier) (qualifier value)|Dependence on|dependence|Dependence (qualifier value)|Dependence|Patient dependence on|dependence on
Dependence
C0392938
null
zoledronate|Zol|Zoledronate (substance)|NDC-Zoledronate|Zoledronate
zoledronate
C0002154
A mixture of metallic elements or compounds with other metallic or metalloid elements in varying proportions.
Metallic alloy (substance)|Metallic alloy, NOS|Alloy|Metallic alloy|alloy|Alloys|alloys
Alloys
C0205838
Elements of the lanthanoid series including atomic number 57 (LANTHANUM) through atomic number 71 (LUTETIUM).
Elements, Lanthanoid Series|Lanthanides|Lanthanoids|lanthanide
Lanthanoid Series Elements
C0043481
A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
Zinc|zn|Zinc, elemental|Zinc (substance)|Zinc, NOS|Zn element|ZINC|Zn - Zinc|zinc|Zn|Zincum metallicum|Zinc-containing product|Product containing zinc (medicinal product)
zinc
C0079717
An integrin heterodimer widely expressed on cells of hematopoietic origin. CD11A ANTIGEN comprises the alpha chain and the CD18 antigen (CD18 ANTIGENS) the beta chain. Lymphocyte function-associated antigen-1 is a major receptor of T-CELLS; B-CELLS; and GRANULOCYTES. It mediates the leukocyte adhesion reactions underlying cytolytic conjugate formation, helper T-cell interactions, and antibody-dependent killing by NATURAL KILLER CELLS and granulocytes. Intracellular adhesion molecule-1 has been defined as a ligand for lymphocyte function-associated antigen-1.
LFA-1 leucocyte adhesive protein|Antigen-1, Lymphocyte Function-Associated|Leukocyte Function Associated Antigen-1|LFA 1|Lymphocyte Function Associated Antigen 1|Leukocyte function associated antigen-1 adhesive protein|LFA-1 leukocyte adhesive protein|Integrin alphaLbeta2|Leucocyte function associated antigen (LFA)-1 adhesive protein|Integrin AlphaLBeta2|Leukocyte function associated antigen-1 adhesive protein (substance)|Alpha-L/Beta-2|Integrin AlphaL/Beta2|Leukocyte function associated antigen (LFA)-1 adhesive protein|LFA-1|alphaLbeta2, Integrin|Integrin Alpha-L/Beta-2|LFA1|Lymphocyte Function-Associated Antigen 1|LFA-1 - lymphocyte function-associated antigen-1|AlphaL/Beta2|CD11a/CD18|Lymphocyte function-associated antigen-1|Lymphocyte Function-Associated Antigen-1
Lymphocyte Function-Associated Antigen-1
C0070805
null
MA PH-IN|phosphoinositolmannoside|phosphatidylinositol monomannoside|phosphatidyl inositol mannoside|mannosylphosphatidylinositol|phosphatidylinositomanoside|mannosyl phosphatidylinositol
phosphatidylinositol mannoside
C0079119
A large family of proteins that have been traditionally classified as the light-harvesting proteins of the photosynthetic reaction complex. Chlorophyll binding proteins are also found in non-photosynthetic settings where they may play a photoprotective role in response to light stress.
Chlorophyll Protein Complexes
Chlorophyll Binding Proteins
C0596341
magnetically induced circular dichroism is the differential absorption of left and right circularly polarized light in the presence of a magnetic field; measurements are made by taking a circular dichroism, or CD measurement, with the magnetization oriented in the positive sense, and then a CD measurement with the magnetization oriented in the negative sense; the two signals are then subtracted.
MCD spectrometry|magnetic circular dichroism
circular magnetic dichroism
C0541095
null
porphine|porphin
porphine
C0018026
A yellow metallic element with the atomic symbol Au, atomic number 79, and atomic weight 197. It is used in jewelry, goldplating of other metals, as currency, and in dental restoration. Many of its clinical applications, such as ANTIRHEUMATIC AGENTS, are in the form of its salts.
gold drug|Au - Gold|Product containing gold (medicinal product)|Gold-containing product|Au element|Golds|gold in a drug form|MEDICINAL GOLD|Gold (substance)|Medicinal gold, NOS|Au|Gold, NOS|gold|GOLD|Gold
gold
C0058496
chemical compound containing two sulfhydryl (thiol) radicals.
dithiol|toluene-3,4-dithiol
dithiol
C0021521
A broad class of substances encompassing all those that do not include carbon and its derivatives as their principal elements. However, carbides, carbonates, cyanides, cyanates, and carbon disulfide are included in this class.
Inorganic Chemicals|Inorganic chemical, NOS|Inorganic Compound|Inorganic Chemical|Inorganic chemical|inorganic compounds|inorganic chemicals|Inorganic compounds|Inorganic compound|Inorganic chemical compound, NOS|Chemicals, Inorganic|Inorganic chemical (substance)|Inorganic chemical compound
Inorganic Chemicals
C1258415
null
EGFP protein
enhanced green fluorescent protein
C0851346
Emission or propagation of acoustic waves (SOUND), ELECTROMAGNETIC ENERGY waves (such as LIGHT; RADIO WAVES; GAMMA RAYS; or X-RAYS), or a stream of subatomic particles (such as ELECTRONS; NEUTRONS; PROTONS; or ALPHA PARTICLES).
Radiation (physical force)|rayed|ray|RADIATION|rays|Radiation, NOS|Rays|ray (radiation)|Radiation|Radiations|radiation|radiation rays|radiations
Radiation
C0544683
null
Reception|receptions
reception
C0043301
The scattering of x-rays by matter, especially crystals, with accompanying variation in intensity due to interference effects. Analysis of the crystal structure of materials is performed by passing x-rays through them and registering the diffraction image of the rays (CRYSTALLOGRAPHY, X-RAY). (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Diffraction, X-Ray|X-rays--Diffraction|X Ray Diffraction|Xray Diffractions|xray diffraction|Diffractions, Xray|Xray Diffraction|Diffraction, Xray|Diffractions, X-Ray|X-Ray Diffractions|x-ray diffraction
X-Ray Diffraction
C0926407
The point of junction of the sagittal and lambdoid sutures of the skull.
Lambda|lambda|Lambda Sutural Junction|Lambda junction
Lambda (Sutural junction)
C0668821
null
null
lysine cyclodeaminase
C0031951
null
2-piperidinecarboxylic acid|Pipecolic acid (substance)|pipecolic acid|Homoproline|Pipecolic acid
pipecolic acid
C0051918
null
shikimin
anisatin
C0452229
null
bourbon|Bourbon (substance)
Bourbon
C0260255
null
null
Chemical ionization mass spectrometry
C0019236
Pesticides used to destroy unwanted vegetation, especially various types of weeds, grasses (POACEAE), and woody plants. Some plants develop HERBICIDE RESISTANCE.
Herbicide (substance)|Weedkiller|weedkiller|Herbicide, NOS|HERBICIDES|herbicide|Herbicide|herbicides|Herbicides
Herbicides
C0136082
null
perchlorate ion|ClO4-|perchlorate
perchlorate
C0012444
A compound used to treat histomoniasis in poultry.
Dimetridazole|DIMETRIDAZOLE|1H-Imidazole, 1,2-dimethyl-5-nitro-
dimetridazole
C0577749
A broad range of biologically active compounds which occur naturally in plants having important medicinal and nutritional properties.
Phytochemicals, Dietary|phytochemicals|Biologically Active Coumpounds, Plant|phytochemical|Compounds, Plant-Derived|Plant-Derived Compounds|Phytonutrient|Compounds, Plant Bioactive|Plant Bioactive Coumpounds|Phytonutrients|Plant Bioactive Compounds|Bioactive Coumpounds, Plant|Product containing phytochemical (product)|Phytochemical-containing product|Plant Biologically Active Compounds|Dietary Phytochemicals|Plant Derived Chemicals|Phytochemical|Chemicals, Plant-Derived|Phytochemical (substance)|Coumpounds, Plant Bioactive|Plant-Derived Chemicals|Plant Derived Compounds|Bioactive Compounds, Plant
Phytochemicals
C0036189
A type of glycoside widely distributed in plants. Each consists of a sapogenin as the aglycone moiety, and a sugar. The sapogenin may be a steroid or a triterpene and the sugar may be glucose, galactose, a pentose, or a methylpentose.
Saponins|saponins
Saponins
C0010209
A daidzein derivative occurring naturally in forage crops which has some estrogenic activity.
COUMESTROL|Cumoestrol|Cumostrol|6H-Benzofuro(3,2-c)(1)benzopyran-6-one, 3,9-dihydroxy-|3,9-dihydroxy-6h-benzofuro(3,2-C)(1)benzopyran-6-one|Coumestrol|coumestrol
Coumestrol
C1136112
A group of compounds which can be described as benzo-pyrano-furano-benzenes which can be formed from ISOFLAVONES by internal coupling of the B ring to the 4-ketone position. Members include medicarpin, phaseolin, and pisatin which are found in FABACEAE.
null
Pterocarpans
C0017011
Penetrating, high-energy electromagnetic radiation emitted from atomic nuclei during NUCLEAR DECAY. The range of wavelengths of emitted radiation is between 0.1 - 100 pm which overlaps the shorter, more energetic hard X-RAYS wavelengths. The distinction between gamma rays and X-rays is based on their radiation source.
Radiations, Gamma|gamma ray|Gamma|Gamma Ray|Gamma Radiation|Gamma radiation (physical force)|Ray, Gamma|Gamma rays|gamma rays|Rays, Gamma|radiation gamma|Gamma radiation|Gamma Radiations|GAMMA RAY|Gamma Rays|Radiation, Gamma|gamma radiation
Gamma Rays
C0330498
null
Brussels sprouts|Brassica oleracea (organism)|Cabbage|kale|brassica oleracea|Brassica oleracea|broccoli|Broccoli|Kale|cabbage
Brassica oleracea
C0076469
null
Thioglucosidase (substance)|myrosinase|thioglucosidase|Thioglucosidase|Myrosinase|Sinigrinase|Sinigrase
Myrosinase
C0768176
null
4-methylsulfinylbutyl glucosinolate|beta-D-glucopyranose, 1-thio-, 1-(5-(methylsulfinyl)-N-(sulfooxy)pentanimidate)|Sulforaphane glucosinolate|Glucoraphanin|glucopyranose, 1-thio-, 1-(5-(methylsulfinyl)valerohydroximate) nO-(hydrogen sulfate), beta-D-|Glucorafanin
glucoraphanin
C0012863
DNA TOPOISOMERASES that catalyze ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. These enzymes bring about relaxation of the supercoiled DNA and resolution of a knotted circular DNA duplex.
DNA topoisomerase II|DNA Topoisomerase II|DNA topoisomerase (ATP-hydrolysing)|Deoxyribonucleic acid topoisomerase (adenosine triphosphate [ATP]-hydrolysing)|DNA Type 2 Topoisomerase|DNA topoisomerase (ATP hydrolyzing)|DNA Topoisomerases, Type II|TOP2|topoisomerase ii|Topoisomerase II|Topoisomerase 2|Type II DNA Topoisomerase|Deoxyribonucleic acid topoisomerase (adenosine triphosphate-hydrolysing)|Topo II|Deoxyribonucleic acid topoisomerase (adenosine triphosphate-hydrolysing) (substance)|DNA Topoisomerase (ATP-Hydrolysing)|Type II DNA topoisomerase|type II DNA topoisomerase
Topoisomerase II
C0007404
An antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin (cis) forms.
Catechin-containing product|Catechin (substance)|(+)-Cyanidan-3-ol|d-Catechin|catechinic acid|cianidanol|(2R,3S)-(+)-Catechin|Catechu|(+)-Cyanidanol|Catechuic Acid|C|(+)-catechin|catechu|(2R,3S)-catechin|CIANIDANOL|(+)-Catechol|(2R,3S)-2-(3,4-dihydroxyphenyl)chroman-3,5,7-triol|Catechin|(2R-trans)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol|Product containing catechin (medicinal product)|D-Catechol|3,3',4',5,7-Flavanpentol|(2R-trans)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol|catechin|cyanidanol|Catechinic Acid|CATECHIN|catechins|Cianidanol|Catechuic acid|Cianidanolum|2H-1-Benzopyran-3,5,7-triol, 2-(3,4-dihydroxyphenyl)-3,4-dihydro-, (2R-trans)-|(+)-Catechin|D-(+)-Catechin
catechin
C0072061
null
procyanidin|procyanidine|procyanidins|2H-1-benzopyran-3,4,5,7-tetrol, 2-(3,4-dihydroxyphenyl)-2-((2-(3,4-dihydroxyphenyl)-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran-3-yl)oxy)-3,4-dihydro-
procyanidin
C1257969
A group of FLAVONOIDS characterized with a 4-ketone.
2-Phenyl-Benzopyran-4-Ones|2 Phenyl Benzopyran 4 Ones
Flavanones