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--- |
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dataset_info: |
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features: |
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- name: vh |
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dtype: string |
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- name: vl |
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dtype: string |
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- name: label |
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dtype: |
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class_label: |
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names: |
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'0': non-binder |
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'1': binder |
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splits: |
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- name: train |
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num_bytes: 4428189 |
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num_examples: 18223 |
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- name: eval |
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num_bytes: 553554 |
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num_examples: 2278 |
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- name: test |
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num_bytes: 553554 |
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num_examples: 2278 |
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download_size: 415916 |
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dataset_size: 5535297 |
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--- |
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# HER2 binding dataset |
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HER2 binding antibodies have been obtained from the [Github repo](https://github.com/dahjan/DMS_opt) for [Mason et al. (2021)](https://www.nature.com/articles/s41551-021-00699-9). |
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Labels for antibody sequences were generated using scripts in the above Github repo. The number of negatives and positives were balanced through random undersampling using [imbalanced-learn](https://github.com/scikit-learn-contrib/imbalanced-learn), and sequences were deduplicated. |
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The dataset has: |
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* 39108 antibodies in total |
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* 22779 antibodies after undersampling and deduplication |
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* 18223 in the training set, 2278 in the evaluation set, and 2278 in the test set. |
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Example |
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| vh_full | vl_full | label | |
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| ------- | ------- | ----- | |
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| EVQ... | DIQ... | 1 | |
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| EVQ... | DIQ... | 0 | |
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| EVQ... | DIQ... | 0 | |
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| EVQ... | DIQ... | 1 | |
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References |
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* [Mason et al. (2021) paper](https://www.nature.com/articles/s41551-021-00699-9) |
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