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{
"aliases": null,
"definition": "A CD24-negative CD38-negative IgG-negative memory B cell is a CD38-negative IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD24-negative, CD38-negative, and IgG-negative.",
"id": "CD24NegativeCD38NegativeIgGNegativeClassSwitchedMemoryBCell",
"label": "CD24-negative CD38-negative IgG-negative class switched memory B cell",
"logical_definition": null,
"original_id": "CL:0002121",
"relationships": [
{
"predicate": "subClassOf",
"target": "CD38NegativeIgGNegativeClassSwitchedMemoryBCell"
}
]
}
| 0 |
{
"document": "CD24-negative CD38-negative IgG-negative class switched memory B cell A CD24-negative CD38-negative IgG-negative memory B cell is a CD38-negative IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD24-negative, CD38-negative, and IgG-negative. [{'predicate': 'subClassOf', 'target': 'CD38NegativeIgGNegativeClassSwitchedMemoryBCell'}]"
}
|
{
"aliases": null,
"definition": "An CD24-positive CD38-negative IgG-negative memory B cell is a CD38-negative IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD24-positive, CD38-negative, and IgG-negative.",
"id": "CD24PositiveCD38NegativeIgGNegativeClassSwitchedMemoryBCell",
"label": "CD24-positive CD38-negative IgG-negative class switched memory B cell",
"logical_definition": null,
"original_id": "CL:0002120",
"relationships": [
{
"predicate": "subClassOf",
"target": "CD38NegativeIgGNegativeClassSwitchedMemoryBCell"
}
]
}
| 0 |
{
"document": "CD24-positive CD38-negative IgG-negative class switched memory B cell An CD24-positive CD38-negative IgG-negative memory B cell is a CD38-negative IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD24-positive, CD38-negative, and IgG-negative. [{'predicate': 'subClassOf', 'target': 'CD38NegativeIgGNegativeClassSwitchedMemoryBCell'}]"
}
|
{
"aliases": null,
"definition": "A CD4-positive, CD8-negative thymocyte that is CD24-positive and expresses high levels of the alpha-beta T cell receptor.",
"id": "CD24Positive_CD4SinglePositiveThymocyte",
"label": "CD24-positive, CD4 single-positive thymocyte",
"logical_definition": null,
"original_id": "CL:0002432",
"relationships": [
{
"predicate": "DevelopsFrom",
"target": "CD69Positive_CD4PositiveSinglePositiveThymocyte"
},
{
"predicate": "subClassOf",
"target": "CD4Positive_alphaBetaThymocyte"
}
]
}
| 0 |
{
"document": "CD24-positive, CD4 single-positive thymocyte A CD4-positive, CD8-negative thymocyte that is CD24-positive and expresses high levels of the alpha-beta T cell receptor. [{'predicate': 'DevelopsFrom', 'target': 'CD69Positive_CD4PositiveSinglePositiveThymocyte'}, {'predicate': 'subClassOf', 'target': 'CD4Positive_alphaBetaThymocyte'}]"
}
|
{
"aliases": null,
"definition": "A CD8-positive, CD4-negative thymocyte that is CD24-positive and expresses high levels of the alpha-beta T cell receptor.",
"id": "CD24Positive_CD8SinglePositiveThymocyte",
"label": "CD24-positive, CD8 single-positive thymocyte",
"logical_definition": null,
"original_id": "CL:0002434",
"relationships": [
{
"predicate": "DevelopsFrom",
"target": "CD69Positive_CD8PositiveSinglePositiveThymocyte"
},
{
"predicate": "subClassOf",
"target": "CD8Positive_alphaBetaThymocyte"
}
]
}
| 0 |
{
"document": "CD24-positive, CD8 single-positive thymocyte A CD8-positive, CD4-negative thymocyte that is CD24-positive and expresses high levels of the alpha-beta T cell receptor. [{'predicate': 'DevelopsFrom', 'target': 'CD69Positive_CD8PositiveSinglePositiveThymocyte'}, {'predicate': 'subClassOf', 'target': 'CD8Positive_alphaBetaThymocyte'}]"
}
|
{
"aliases": null,
"definition": "A CD25-positive, CD27-positive immature gamma-delta T cell found in the thymus that has an immature phenotype (i.e. CD24-high, CD25-high, CD62L-high, CD44-high, CD2-low, CD5-low).",
"id": "CD25Positive_CD27PositiveImmatureGammaDeltaTCell",
"label": "CD25-positive, CD27-positive immature gamma-delta T cell",
"logical_definition": null,
"original_id": "CL:0002126",
"relationships": [
{
"predicate": "subClassOf",
"target": "ImmatureGammaDeltaTCell"
}
]
}
| 0 |
{
"document": "CD25-positive, CD27-positive immature gamma-delta T cell A CD25-positive, CD27-positive immature gamma-delta T cell found in the thymus that has an immature phenotype (i.e. CD24-high, CD25-high, CD62L-high, CD44-high, CD2-low, CD5-low). [{'predicate': 'subClassOf', 'target': 'ImmatureGammaDeltaTCell'}]"
}
|
{
"aliases": null,
"definition": "A protein that is a translation product of the human CD27 gene or a 1:1 ortholog thereof.",
"id": "CD27Molecule",
"label": "CD27 molecule",
"logical_definition": null,
"original_id": "PR:000001963",
"relationships": [
{
"predicate": "subClassOf",
"target": "Protein_PR:000000001"
}
]
}
| 0 |
{
"document": "CD27 molecule A protein that is a translation product of the human CD27 gene or a 1:1 ortholog thereof. [{'predicate': 'subClassOf', 'target': 'Protein_PR:000000001'}]"
}
|
{
"aliases": null,
"definition": "A circulating gamma-delta T cell that is CD27-positive and capable of producing IFN-gamma.",
"id": "CD27PositiveGammaDeltaTCell",
"label": "CD27-positive gamma-delta T cell",
"logical_definition": null,
"original_id": "CL:0002124",
"relationships": [
{
"predicate": "DevelopsFrom",
"target": "CD25Positive_CD27PositiveImmatureGammaDeltaTCell"
},
{
"predicate": "subClassOf",
"target": "MatureGammaDeltaTCell"
}
]
}
| 0 |
{
"document": "CD27-positive gamma-delta T cell A circulating gamma-delta T cell that is CD27-positive and capable of producing IFN-gamma. [{'predicate': 'DevelopsFrom', 'target': 'CD25Positive_CD27PositiveImmatureGammaDeltaTCell'}, {'predicate': 'subClassOf', 'target': 'MatureGammaDeltaTCell'}]"
}
|
{
"aliases": null,
"definition": "A protein that is a translation product of the human CD2 gene or a 1:1 ortholog thereof.",
"id": "CD2Molecule",
"label": "CD2 molecule",
"logical_definition": null,
"original_id": "PR:000001083",
"relationships": [
{
"predicate": "subClassOf",
"target": "Protein_PR:000000001"
}
]
}
| 0 |
{
"document": "CD2 molecule A protein that is a translation product of the human CD2 gene or a 1:1 ortholog thereof. [{'predicate': 'subClassOf', 'target': 'Protein_PR:000000001'}]"
}
|
{
"aliases": null,
"definition": "A CD2 molecule that has been processed by proteolytic cleavage.",
"id": "CD2MoleculeProteolyticCleavageProduct",
"label": "CD2 molecule proteolytic cleavage product",
"logical_definition": null,
"original_id": "PR:000025455",
"relationships": [
{
"predicate": "OutputOf",
"target": "ProteinProcessing"
},
{
"predicate": "subClassOf",
"target": "CD2Molecule"
},
{
"predicate": "subClassOf",
"target": "ProteolyticCleavageProduct"
}
]
}
| 0 |
{
"document": "CD2 molecule proteolytic cleavage product A CD2 molecule that has been processed by proteolytic cleavage. [{'predicate': 'OutputOf', 'target': 'ProteinProcessing'}, {'predicate': 'subClassOf', 'target': 'CD2Molecule'}, {'predicate': 'subClassOf', 'target': 'ProteolyticCleavageProduct'}]"
}
|
{
"aliases": null,
"definition": "A protein that is a translation product of the human CD33 gene or a 1:1 ortholog thereof.",
"id": "CD33Molecule",
"label": "CD33 molecule",
"logical_definition": null,
"original_id": "PR:000001892",
"relationships": [
{
"predicate": "subClassOf",
"target": "Protein_PR:000000001"
}
]
}
| 0 |
{
"document": "CD33 molecule A protein that is a translation product of the human CD33 gene or a 1:1 ortholog thereof. [{'predicate': 'subClassOf', 'target': 'Protein_PR:000000001'}]"
}
|
{
"aliases": null,
"definition": "A protein that is a translation product of the human CD34 gene or a 1:1 ortholog thereof. It is a leukocyte membrane protein expressed specifically by lymphohematopoietic progenitor cells. It contains a single-pass transmembrane domain and that show distinct expression on early hematopoietic precursors and vascular-associated tissue. Acts as a scaffold that presents selectin carbohydrate ligands in a clustered, tissue specific manner to allow for higher avidity interactions between leukocytes and endothelial cells during the inflammatory process. In common with related sialomucins (endoglycan and podocalyxin), the extracellular region is dominated by an N-terminal mucin-like domain, which is densely substituted with sialylated O-linked carbohydrates. The mucin-like region is followed by a cysteine-containing and presumably globular domain. This domain may fold into an immunoglobulin-like structure as the positions of 2 of the cysteines are conserved in the C2 set of the immunoglobulin superfamily. The cytoplasmic domain is around 73-76 residues long and highly conserved.",
"id": "CD34Molecule",
"label": "CD34 molecule",
"logical_definition": null,
"original_id": "PR:000001003",
"relationships": [
{
"predicate": "subClassOf",
"target": "Protein_PR:000000001"
}
]
}
| 0 |
{
"document": "CD34 molecule A protein that is a translation product of the human CD34 gene or a 1:1 ortholog thereof. It is a leukocyte membrane protein expressed specifically by lymphohematopoietic progenitor cells. It contains a single-pass transmembrane domain and that show distinct expression on early hematopoietic precursors and vascular-associated tissue. Acts as a scaffold that presents selectin carbohydrate ligands in a clustered, tissue specific manner to allow for higher avidity interactions between leukocytes and endothelial cells during the inflammatory process. In common with related sialomucins (endoglycan and podocalyxin), the extracellular region is dominated by an N-terminal mucin-like domain, which is densely substituted with sialylated O-linked carbohydrates. The mucin-like region is followed by a cysteine-containing and presumably globular domain. This domain may fold into an immunoglobulin-like structure as the positions of 2 of the cysteines are conserved in the C2 set of the immunoglobulin superfamily. The cytoplasmic domain is around 73-76 residues long and highly conserved. [{'predicate': 'subClassOf', 'target': 'Protein_PR:000000001'}]"
}
|
{
"aliases": null,
"definition": "A proerythoblast that is CD34-negative and GlyA-negative.",
"id": "CD34Negative_GlyANegativeProerythroblast",
"label": "CD34-negative, GlyA-negative proerythroblast",
"logical_definition": null,
"original_id": "CL:0002004",
"relationships": [
{
"predicate": "DevelopsFrom",
"target": "CD34Positive_GlyANegativeErythroidProgenitorCell"
},
{
"predicate": "subClassOf",
"target": "Proerythroblast"
}
]
}
| 0 |
{
"document": "CD34-negative, GlyA-negative proerythroblast A proerythoblast that is CD34-negative and GlyA-negative. [{'predicate': 'DevelopsFrom', 'target': 'CD34Positive_GlyANegativeErythroidProgenitorCell'}, {'predicate': 'subClassOf', 'target': 'Proerythroblast'}]"
}
|
{
"aliases": null,
"definition": "CD133-positive hematopoietic stem cell is a hematopoietic stem cell that is CD34-positive, CD90-positive, and CD133-positive.",
"id": "CD34Positive_CD38NegativeHematopoieticStemCell",
"label": "CD34-positive, CD38-negative hematopoietic stem cell",
"logical_definition": null,
"original_id": "CL:0001024",
"relationships": [
{
"predicate": "subClassOf",
"target": "HematopoieticStemCell"
}
]
}
| 0 |
{
"document": "CD34-positive, CD38-negative hematopoietic stem cell CD133-positive hematopoietic stem cell is a hematopoietic stem cell that is CD34-positive, CD90-positive, and CD133-positive. [{'predicate': 'subClassOf', 'target': 'HematopoieticStemCell'}]"
}
|
{
"aliases": null,
"definition": "A hematopoietic multipotent progenitor cell that is CD34-positive, CD38-negative, CD45RA-negative, and CD90-negative.",
"id": "CD34Positive_CD38NegativeMultipotentProgenitorCell",
"label": "CD34-positive, CD38-negative multipotent progenitor cell",
"logical_definition": null,
"original_id": "CL:0002043",
"relationships": [
{
"predicate": "DevelopsFrom",
"target": "CD34Positive_CD38NegativeHematopoieticStemCell"
},
{
"predicate": "subClassOf",
"target": "HematopoieticMultipotentProgenitorCell"
}
]
}
| 0 |
{
"document": "CD34-positive, CD38-negative multipotent progenitor cell A hematopoietic multipotent progenitor cell that is CD34-positive, CD38-negative, CD45RA-negative, and CD90-negative. [{'predicate': 'DevelopsFrom', 'target': 'CD34Positive_CD38NegativeHematopoieticStemCell'}, {'predicate': 'subClassOf', 'target': 'HematopoieticMultipotentProgenitorCell'}]"
}
|
{
"aliases": null,
"definition": "A common lymphoid progenitor that is CD10-positive, CD45RA-positive, CD34-positive and CD38-positive.",
"id": "CD34Positive_CD38PositiveCommonLymphoidProgenitor",
"label": "CD34-positive, CD38-positive common lymphoid progenitor",
"logical_definition": null,
"original_id": "CL:0001021",
"relationships": [
{
"predicate": "DevelopsFrom",
"target": "CD34Positive_CD38NegativeMultipotentProgenitorCell"
},
{
"predicate": "subClassOf",
"target": "CommonLymphoidProgenitor"
}
]
}
| 0 |
{
"document": "CD34-positive, CD38-positive common lymphoid progenitor A common lymphoid progenitor that is CD10-positive, CD45RA-positive, CD34-positive and CD38-positive. [{'predicate': 'DevelopsFrom', 'target': 'CD34Positive_CD38NegativeMultipotentProgenitorCell'}, {'predicate': 'subClassOf', 'target': 'CommonLymphoidProgenitor'}]"
}
|
{
"aliases": null,
"definition": "A common myeloid progenitor that is CD34-positive, CD38-positive, IL3ra-low, CD10-negative, CD7-negative, CD45RA-negative, and IL-5Ralpha-negative.",
"id": "CD34Positive_CD38PositiveCommonMyeloidProgenitor",
"label": "CD34-positive, CD38-positive common myeloid progenitor",
"logical_definition": null,
"original_id": "CL:0001026",
"relationships": [
{
"predicate": "DevelopsFrom",
"target": "CD34Positive_CD38NegativeMultipotentProgenitorCell"
},
{
"predicate": "subClassOf",
"target": "CommonMyeloidProgenitor_CD34Positive"
}
]
}
| 0 |
{
"document": "CD34-positive, CD38-positive common myeloid progenitor A common myeloid progenitor that is CD34-positive, CD38-positive, IL3ra-low, CD10-negative, CD7-negative, CD45RA-negative, and IL-5Ralpha-negative. [{'predicate': 'DevelopsFrom', 'target': 'CD34Positive_CD38NegativeMultipotentProgenitorCell'}, {'predicate': 'subClassOf', 'target': 'CommonMyeloidProgenitor_CD34Positive'}]"
}
|
{
"aliases": null,
"definition": null,
"id": "CD34Positive_CD38PositiveCommonMyeloidProgenitorORCD34Positive_CD38PositiveCommonLymphoidProgenitor",
"label": "CD34-positive, CD38-positive common myeloid progenitor OR CD34-positive, CD38-positive common lymphoid progenitor",
"logical_definition": null,
"original_id": "CL:0000995",
"relationships": [
{
"predicate": "subClassOf",
"target": "HematopoieticOligopotentProgenitorCell_lineageNegative"
}
]
}
| 0 |
{
"document": "CD34-positive, CD38-positive common myeloid progenitor OR CD34-positive, CD38-positive common lymphoid progenitor None [{'predicate': 'subClassOf', 'target': 'HematopoieticOligopotentProgenitorCell_lineageNegative'}]"
}
|
{
"aliases": null,
"definition": "A granulocyte monocyte progenitor is CD34-positive, CD38-positive, IL-3receptor-alpha-positive and is CD45RA-negative.",
"id": "CD34Positive_CD38PositiveGranulocyteMonocyteProgenitor",
"label": "CD34-positive, CD38-positive granulocyte monocyte progenitor",
"logical_definition": null,
"original_id": "CL:0002001",
"relationships": [
{
"predicate": "DevelopsFrom",
"target": "CD34Positive_CD38PositiveCommonMyeloidProgenitor"
},
{
"predicate": "subClassOf",
"target": "GranulocyteMonocyteProgenitorCell"
}
]
}
| 0 |
{
"document": "CD34-positive, CD38-positive granulocyte monocyte progenitor A granulocyte monocyte progenitor is CD34-positive, CD38-positive, IL-3receptor-alpha-positive and is CD45RA-negative. [{'predicate': 'DevelopsFrom', 'target': 'CD34Positive_CD38PositiveCommonMyeloidProgenitor'}, {'predicate': 'subClassOf', 'target': 'GranulocyteMonocyteProgenitorCell'}]"
}
|
{
"aliases": null,
"definition": "A megakaryocyte erythroid progenitor cell is CD34-positive, CD38-positive and is IL3-receptor alpha-negative and CD45RA-negative.",
"id": "CD34Positive_CD38PositiveMegakaryocyteErythroidProgenitorCell",
"label": "CD34-positive, CD38-positive megakaryocyte erythroid progenitor cell",
"logical_definition": null,
"original_id": "CL:0002005",
"relationships": [
{
"predicate": "subClassOf",
"target": "MegakaryocyteErythroidProgenitorCell"
}
]
}
| 0 |
{
"document": "CD34-positive, CD38-positive megakaryocyte erythroid progenitor cell A megakaryocyte erythroid progenitor cell is CD34-positive, CD38-positive and is IL3-receptor alpha-negative and CD45RA-negative. [{'predicate': 'subClassOf', 'target': 'MegakaryocyteErythroidProgenitorCell'}]"
}
|
{
"aliases": null,
"definition": "An erythroid progenitor cell that is CD34-positive and is GlyA-negative.",
"id": "CD34Positive_GlyANegativeErythroidProgenitorCell",
"label": "CD34-positive, GlyA-negative erythroid progenitor cell",
"logical_definition": null,
"original_id": "CL:0002003",
"relationships": [
{
"predicate": "DevelopsFrom",
"target": "CD34Positive_CD38PositiveMegakaryocyteErythroidProgenitorCell"
},
{
"predicate": "subClassOf",
"target": "ErythroidProgenitorCell_mammalian"
}
]
}
| 0 |
{
"document": "CD34-positive, GlyA-negative erythroid progenitor cell An erythroid progenitor cell that is CD34-positive and is GlyA-negative. [{'predicate': 'DevelopsFrom', 'target': 'CD34Positive_CD38PositiveMegakaryocyteErythroidProgenitorCell'}, {'predicate': 'subClassOf', 'target': 'ErythroidProgenitorCell_mammalian'}]"
}
|
{
"aliases": null,
"definition": "A CD38-negative IgG memory B cell is a IgG-positive class switched memory B cell that has class switched and expresses IgG on the cell surface with the phenotype CD38-negative, IgD-negative, and IgG-positive.",
"id": "CD38NegativeIgGMemoryBCell",
"label": "CD38-negative IgG memory B cell",
"logical_definition": null,
"original_id": "CL:0002108",
"relationships": [
{
"predicate": "subClassOf",
"target": "IgGMemoryBCell"
}
]
}
| 0 |
{
"document": "CD38-negative IgG memory B cell A CD38-negative IgG memory B cell is a IgG-positive class switched memory B cell that has class switched and expresses IgG on the cell surface with the phenotype CD38-negative, IgD-negative, and IgG-positive. [{'predicate': 'subClassOf', 'target': 'IgGMemoryBCell'}]"
}
|
{
"aliases": null,
"definition": "A CD38-negative IgG-negative memory B cell is a IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD38-negative and IgG-negative.",
"id": "CD38NegativeIgGNegativeClassSwitchedMemoryBCell",
"label": "CD38-negative IgG-negative class switched memory B cell",
"logical_definition": null,
"original_id": "CL:0002118",
"relationships": [
{
"predicate": "subClassOf",
"target": "IgGNegativeClassSwitchedMemoryBCell"
}
]
}
| 0 |
{
"document": "CD38-negative IgG-negative class switched memory B cell A CD38-negative IgG-negative memory B cell is a IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD38-negative and IgG-negative. [{'predicate': 'subClassOf', 'target': 'IgGNegativeClassSwitchedMemoryBCell'}]"
}
|
{
"aliases": null,
"definition": "A CD38-negative naive B cell is a mature B cell that has the phenotype CD38-negative, surface IgD-positive, surface IgM-positive, and CD27-negative, that has not yet been activated by antigen in the periphery.",
"id": "CD38NegativeNaiveBCell",
"label": "CD38-negative naive B cell",
"logical_definition": null,
"original_id": "CL:0002102",
"relationships": [
{
"predicate": "subClassOf",
"target": "NaiveBCell"
}
]
}
| 0 |
{
"document": "CD38-negative naive B cell A CD38-negative naive B cell is a mature B cell that has the phenotype CD38-negative, surface IgD-positive, surface IgM-positive, and CD27-negative, that has not yet been activated by antigen in the periphery. [{'predicate': 'subClassOf', 'target': 'NaiveBCell'}]"
}
|
{
"aliases": null,
"definition": "An CD38-negative unswitched memory B cell is an unswitched memory B cell that has the phenotype CD38-negative, IgD-positive, CD138-negative, and IgG-negative.",
"id": "CD38NegativeUnswitchedMemoryBCell",
"label": "CD38-negative unswitched memory B cell",
"logical_definition": null,
"original_id": "CL:0002111",
"relationships": [
{
"predicate": "subClassOf",
"target": "UnswitchedMemoryBCell"
}
]
}
| 0 |
{
"document": "CD38-negative unswitched memory B cell An CD38-negative unswitched memory B cell is an unswitched memory B cell that has the phenotype CD38-negative, IgD-positive, CD138-negative, and IgG-negative. [{'predicate': 'subClassOf', 'target': 'UnswitchedMemoryBCell'}]"
}
|
{
"aliases": null,
"definition": "A CD38-positive IgG memory B cell is a class switched memory B cell that expresses IgG on the cell surface with the phenotype CD38-positive and IgG-positive.",
"id": "CD38PositiveIgGMemoryBCell",
"label": "CD38-positive IgG memory B cell",
"logical_definition": null,
"original_id": "CL:0002105",
"relationships": [
{
"predicate": "subClassOf",
"target": "IgGMemoryBCell"
}
]
}
| 0 |
{
"document": "CD38-positive IgG memory B cell A CD38-positive IgG memory B cell is a class switched memory B cell that expresses IgG on the cell surface with the phenotype CD38-positive and IgG-positive. [{'predicate': 'subClassOf', 'target': 'IgGMemoryBCell'}]"
}
|
{
"aliases": null,
"definition": "A CD38-positive IgG-negative memory B cell is an IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD38-positive and IgG-negative.",
"id": "CD38PositiveIgGNegativeClassSwitchedMemoryBCell",
"label": "CD38-positive IgG-negative class switched memory B cell",
"logical_definition": null,
"original_id": "CL:0002119",
"relationships": [
{
"predicate": "subClassOf",
"target": "IgGNegativeClassSwitchedMemoryBCell"
}
]
}
| 0 |
{
"document": "CD38-positive IgG-negative class switched memory B cell A CD38-positive IgG-negative memory B cell is an IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD38-positive and IgG-negative. [{'predicate': 'subClassOf', 'target': 'IgGNegativeClassSwitchedMemoryBCell'}]"
}
|
{
"aliases": null,
"definition": "A CD38-positive naive B cell is a mature B cell that has the phenotype CD38-positive, surface IgD-positive, surface IgM-positive, and CD27-negative, and that has not yet been activated by antigen in the periphery.",
"id": "CD38PositiveNaiveBCell",
"label": "CD38-positive naive B cell",
"logical_definition": null,
"original_id": "CL:0002101",
"relationships": [
{
"predicate": "subClassOf",
"target": "NaiveBCell"
}
]
}
| 0 |
{
"document": "CD38-positive naive B cell A CD38-positive naive B cell is a mature B cell that has the phenotype CD38-positive, surface IgD-positive, surface IgM-positive, and CD27-negative, and that has not yet been activated by antigen in the periphery. [{'predicate': 'subClassOf', 'target': 'NaiveBCell'}]"
}
|
{
"aliases": null,
"definition": "A CD38-positive unswitched memory B cell is an unswitched memory B cell that has the phenotype CD38-positive, IgD-positive, CD138-negative, and IgG-negative.",
"id": "CD38PositiveUnswitchedMemoryBCell",
"label": "CD38-positive unswitched memory B cell",
"logical_definition": null,
"original_id": "CL:0002114",
"relationships": [
{
"predicate": "subClassOf",
"target": "UnswitchedMemoryBCell"
}
]
}
| 0 |
{
"document": "CD38-positive unswitched memory B cell A CD38-positive unswitched memory B cell is an unswitched memory B cell that has the phenotype CD38-positive, IgD-positive, CD138-negative, and IgG-negative. [{'predicate': 'subClassOf', 'target': 'UnswitchedMemoryBCell'}]"
}
|
{
"aliases": null,
"definition": "A CD3 subunit with immunoglobulin domain that is a translation product of the human CD3E gene or a 1:1 ortholog thereof.",
"id": "CD3Epsilon",
"label": "CD3 epsilon",
"logical_definition": null,
"original_id": "PR:000001020",
"relationships": [
{
"predicate": "subClassOf",
"target": "CD3SubunitWithImmunoglobulinDomain"
}
]
}
| 0 |
{
"document": "CD3 epsilon A CD3 subunit with immunoglobulin domain that is a translation product of the human CD3E gene or a 1:1 ortholog thereof. [{'predicate': 'subClassOf', 'target': 'CD3SubunitWithImmunoglobulinDomain'}]"
}
|
{
"aliases": null,
"definition": "A protein that has a core domain composition consisting of an extracellular N-terminal domain that adopts an immunoglobulin fold, a transmembrane domain, and an intracellular C-terminal domain with a single copy of the Immunoreceptor tyrosine-based activation motif (Pfam:PF02189) (ITAM). It constitutes the invariant subunit of the T cell antigen receptor (TCR). TCR is a surface receptor on T cells responsible for recognizing MHC-restricted antigens and initiating the cellular immune response.",
"id": "CD3SubunitWithImmunoglobulinDomain",
"label": "CD3 subunit with immunoglobulin domain",
"logical_definition": null,
"original_id": "PR:000001018",
"relationships": [
{
"predicate": "subClassOf",
"target": "Protein_PR:000000001"
}
]
}
| 0 |
{
"document": "CD3 subunit with immunoglobulin domain A protein that has a core domain composition consisting of an extracellular N-terminal domain that adopts an immunoglobulin fold, a transmembrane domain, and an intracellular C-terminal domain with a single copy of the Immunoreceptor tyrosine-based activation motif (Pfam:PF02189) (ITAM). It constitutes the invariant subunit of the T cell antigen receptor (TCR). TCR is a surface receptor on T cells responsible for recognizing MHC-restricted antigens and initiating the cellular immune response. [{'predicate': 'subClassOf', 'target': 'Protein_PR:000000001'}]"
}
|
{
"aliases": null,
"definition": "A protein that is a translation product of the human CD44 gene or a 1:1 ortholog thereof.",
"id": "CD44Molecule",
"label": "CD44 molecule",
"logical_definition": null,
"original_id": "PR:000001307",
"relationships": [
{
"predicate": "subClassOf",
"target": "Protein_PR:000000001"
}
]
}
| 0 |
{
"document": "CD44 molecule A protein that is a translation product of the human CD44 gene or a 1:1 ortholog thereof. [{'predicate': 'subClassOf', 'target': 'Protein_PR:000000001'}]"
}
|
{
"aliases": null,
"definition": "A protein that is a translation product of the human CD48 gene or a 1:1 ortholog thereof.",
"id": "CD48Molecule",
"label": "CD48 molecule",
"logical_definition": null,
"original_id": "PR:000001308",
"relationships": [
{
"predicate": "subClassOf",
"target": "Protein_PR:000000001"
}
]
}
| 0 |
{
"document": "CD48 molecule A protein that is a translation product of the human CD48 gene or a 1:1 ortholog thereof. [{'predicate': 'subClassOf', 'target': 'Protein_PR:000000001'}]"
}
|
{
"aliases": null,
"definition": "A CD48 molecule that has been processed by proteolytic cleavage.",
"id": "CD48MoleculeProteolyticCleavageProduct",
"label": "CD48 molecule proteolytic cleavage product",
"logical_definition": null,
"original_id": "PR:000018381",
"relationships": [
{
"predicate": "OutputOf",
"target": "ProteinProcessing"
},
{
"predicate": "subClassOf",
"target": "CD48Molecule"
},
{
"predicate": "subClassOf",
"target": "ProteolyticCleavageProduct"
}
]
}
| 0 |
{
"document": "CD48 molecule proteolytic cleavage product A CD48 molecule that has been processed by proteolytic cleavage. [{'predicate': 'OutputOf', 'target': 'ProteinProcessing'}, {'predicate': 'subClassOf', 'target': 'CD48Molecule'}, {'predicate': 'subClassOf', 'target': 'ProteolyticCleavageProduct'}]"
}
|
{
"aliases": null,
"definition": "A double-positive thymocyte that is undergoing positive selection, has high expression of the alpha-beta T cell receptor, is CD69-positive, and is in the process of down regulating the CD4 co-receptor.",
"id": "CD4Intermediate_CD8PositiveDoublePositiveThymocyte",
"label": "CD4-intermediate, CD8-positive double-positive thymocyte",
"logical_definition": null,
"original_id": "CL:0002430",
"relationships": [
{
"predicate": "DevelopsFrom",
"target": "CD69PositiveDoublePositiveThymocyte"
},
{
"predicate": "subClassOf",
"target": "DoublePositive_alphaBetaThymocyte"
}
]
}
| 0 |
{
"document": "CD4-intermediate, CD8-positive double-positive thymocyte A double-positive thymocyte that is undergoing positive selection, has high expression of the alpha-beta T cell receptor, is CD69-positive, and is in the process of down regulating the CD4 co-receptor. [{'predicate': 'DevelopsFrom', 'target': 'CD69PositiveDoublePositiveThymocyte'}, {'predicate': 'subClassOf', 'target': 'DoublePositive_alphaBetaThymocyte'}]"
}
|
{
"aliases": null,
"definition": "A protein that is a translation product of the human CD4 gene or a 1:1 ortholog thereof. CD4 is an accessory protein for MHC class-II antigen/T-cell receptor interaction. It is the primary receptor for HIV-1. CD4 has four immunoglobulin-like domains in its extracellular region that share the same structure, but can differ in sequence.",
"id": "CD4Molecule",
"label": "CD4 molecule",
"logical_definition": null,
"original_id": "PR:000001004",
"relationships": [
{
"predicate": "subClassOf",
"target": "Protein_PR:000000001"
}
]
}
| 0 |
{
"document": "CD4 molecule A protein that is a translation product of the human CD4 gene or a 1:1 ortholog thereof. CD4 is an accessory protein for MHC class-II antigen/T-cell receptor interaction. It is the primary receptor for HIV-1. CD4 has four immunoglobulin-like domains in its extracellular region that share the same structure, but can differ in sequence. [{'predicate': 'subClassOf', 'target': 'Protein_PR:000000001'}]"
}
|
{
"aliases": null,
"definition": "A CD4-positive, alpha-beta T cell that cooperates with other lymphocytes via direct contact or cytokine release to initiate a variety of immune functions.",
"id": "CD4PositiveHelperTCell",
"label": "CD4-positive helper T cell",
"logical_definition": null,
"original_id": "CL:0000492",
"relationships": [
{
"predicate": "DevelopsFrom",
"target": "ActivatedCD4Positive_alphaBetaTCell"
},
{
"predicate": "OutputOf",
"target": "TCellDifferentiation"
},
{
"predicate": "subClassOf",
"target": "CD4Positive_alphaBetaTCell"
}
]
}
| 0 |
{
"document": "CD4-positive helper T cell A CD4-positive, alpha-beta T cell that cooperates with other lymphocytes via direct contact or cytokine release to initiate a variety of immune functions. [{'predicate': 'DevelopsFrom', 'target': 'ActivatedCD4Positive_alphaBetaTCell'}, {'predicate': 'OutputOf', 'target': 'TCellDifferentiation'}, {'predicate': 'subClassOf', 'target': 'CD4Positive_alphaBetaTCell'}]"
}
|
{
"aliases": null,
"definition": "A CD4-positive, CD25-positive, alpha-beta T cell that regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release.",
"id": "CD4Positive_CD25Positive_alphaBetaRegulatoryTCell",
"label": "CD4-positive, CD25-positive, alpha-beta regulatory T cell",
"logical_definition": null,
"original_id": "CL:0000792",
"relationships": [
{
"predicate": "subClassOf",
"target": "CD4Positive_alphaBetaTCell"
}
]
}
| 0 |
{
"document": "CD4-positive, CD25-positive, alpha-beta regulatory T cell A CD4-positive, CD25-positive, alpha-beta T cell that regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release. [{'predicate': 'subClassOf', 'target': 'CD4Positive_alphaBetaTCell'}]"
}
|
{
"aliases": null,
"definition": "A double-positive thymocyte that is undergoing positive selection, has high expression of the alpha-beta T cell receptor, is CD69-positive, and is in the process of down regulating the CD8 co-receptor.",
"id": "CD4Positive_CD8IntermediateDoublePositiveThymocyte",
"label": "CD4-positive, CD8-intermediate double-positive thymocyte",
"logical_definition": null,
"original_id": "CL:0002431",
"relationships": [
{
"predicate": "DevelopsFrom",
"target": "CD69PositiveDoublePositiveThymocyte"
},
{
"predicate": "subClassOf",
"target": "DoublePositive_alphaBetaThymocyte"
}
]
}
| 0 |
{
"document": "CD4-positive, CD8-intermediate double-positive thymocyte A double-positive thymocyte that is undergoing positive selection, has high expression of the alpha-beta T cell receptor, is CD69-positive, and is in the process of down regulating the CD8 co-receptor. [{'predicate': 'DevelopsFrom', 'target': 'CD69PositiveDoublePositiveThymocyte'}, {'predicate': 'subClassOf', 'target': 'DoublePositive_alphaBetaThymocyte'}]"
}
|
{
"aliases": null,
"definition": "A CD4-positive, alpha-beta T cell that has differentiated into a memory T cell.",
"id": "CD4Positive_alphaBetaMemoryTCell",
"label": "CD4-positive, alpha-beta memory T cell",
"logical_definition": null,
"original_id": "CL:0000897",
"relationships": [
{
"predicate": "subClassOf",
"target": "CD4Positive_alphaBetaTCell"
}
]
}
| 0 |
{
"document": "CD4-positive, alpha-beta memory T cell A CD4-positive, alpha-beta T cell that has differentiated into a memory T cell. [{'predicate': 'subClassOf', 'target': 'CD4Positive_alphaBetaTCell'}]"
}
|
{
"aliases": null,
"definition": "CD4-positive, alpha-beta long-lived T cell with the phenotype CD45RO-positive and CD127-positive. This cell type is also described as being CD25-negative, CD44-high, and CD122-high.",
"id": "CD4Positive_alphaBetaMemoryTCell_CD45ROPositive",
"label": "CD4-positive, alpha-beta memory T cell, CD45RO-positive",
"logical_definition": null,
"original_id": "CL:0001204",
"relationships": [
{
"predicate": "DevelopsFrom",
"target": "ActivatedCD4Positive_alphaBetaTCell"
},
{
"predicate": "subClassOf",
"target": "CD4Positive_alphaBetaMemoryTCell"
}
]
}
| 0 |
{
"document": "CD4-positive, alpha-beta memory T cell, CD45RO-positive CD4-positive, alpha-beta long-lived T cell with the phenotype CD45RO-positive and CD127-positive. This cell type is also described as being CD25-negative, CD44-high, and CD122-high. [{'predicate': 'DevelopsFrom', 'target': 'ActivatedCD4Positive_alphaBetaTCell'}, {'predicate': 'subClassOf', 'target': 'CD4Positive_alphaBetaMemoryTCell'}]"
}
|
{
"aliases": null,
"definition": "A mature alpha-beta T cell that expresses an alpha-beta T cell receptor and the CD4 coreceptor.",
"id": "CD4Positive_alphaBetaTCell",
"label": "CD4-positive, alpha-beta T cell",
"logical_definition": null,
"original_id": "CL:0000624",
"relationships": [
{
"predicate": "subClassOf",
"target": "MatureAlphaBetaTCell"
}
]
}
| 0 |
{
"document": "CD4-positive, alpha-beta T cell A mature alpha-beta T cell that expresses an alpha-beta T cell receptor and the CD4 coreceptor. [{'predicate': 'subClassOf', 'target': 'MatureAlphaBetaTCell'}]"
}
|
{
"aliases": null,
"definition": "An immature alpha-beta T cell that is located in the thymus and is CD4-positive and CD8-negative.",
"id": "CD4Positive_alphaBetaThymocyte",
"label": "CD4-positive, alpha-beta thymocyte",
"logical_definition": null,
"original_id": "CL:0000810",
"relationships": [
{
"predicate": "DevelopsFrom",
"target": "DoublePositive_alphaBetaThymocyte"
},
{
"predicate": "subClassOf",
"target": "ImmatureAlphaBetaTCell"
}
]
}
| 0 |
{
"document": "CD4-positive, alpha-beta thymocyte An immature alpha-beta T cell that is located in the thymus and is CD4-positive and CD8-negative. [{'predicate': 'DevelopsFrom', 'target': 'DoublePositive_alphaBetaThymocyte'}, {'predicate': 'subClassOf', 'target': 'ImmatureAlphaBetaTCell'}]"
}
|
{
"aliases": null,
"definition": "A protein that is a translation product of the human CD59 gene, a 1:1 ortholog thereof, or pro-orthologs thereof.",
"id": "CD59LikeGlycoprotein",
"label": "CD59-like glycoprotein",
"logical_definition": null,
"original_id": "PR:000001809",
"relationships": [
{
"predicate": "subClassOf",
"target": "Protein_PR:000000001"
}
]
}
| 0 |
{
"document": "CD59-like glycoprotein A protein that is a translation product of the human CD59 gene, a 1:1 ortholog thereof, or pro-orthologs thereof. [{'predicate': 'subClassOf', 'target': 'Protein_PR:000000001'}]"
}
|
{
"aliases": null,
"definition": "A protein that is a translation product of the human CD69 gene or a 1:1 ortholog thereof. A type II transmembrane protein with a C-type lectin binding domain in the extracellular portion of the molecule. Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets.",
"id": "CD69Molecule",
"label": "CD69 molecule",
"logical_definition": null,
"original_id": "PR:000001343",
"relationships": [
{
"predicate": "subClassOf",
"target": "Protein_PR:000000001"
}
]
}
| 0 |
{
"document": "CD69 molecule A protein that is a translation product of the human CD69 gene or a 1:1 ortholog thereof. A type II transmembrane protein with a C-type lectin binding domain in the extracellular portion of the molecule. Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets. [{'predicate': 'subClassOf', 'target': 'Protein_PR:000000001'}]"
}
|
{
"aliases": null,
"definition": "A double-positive thymocyte that is CD69-positive and has begun positive selection.",
"id": "CD69PositiveDoublePositiveThymocyte",
"label": "CD69-positive double-positive thymocyte",
"logical_definition": null,
"original_id": "CL:0002429",
"relationships": [
{
"predicate": "DevelopsFrom",
"target": "DoublePositiveBlast"
},
{
"predicate": "subClassOf",
"target": "DoublePositive_alphaBetaThymocyte"
}
]
}
| 0 |
{
"document": "CD69-positive double-positive thymocyte A double-positive thymocyte that is CD69-positive and has begun positive selection. [{'predicate': 'DevelopsFrom', 'target': 'DoublePositiveBlast'}, {'predicate': 'subClassOf', 'target': 'DoublePositive_alphaBetaThymocyte'}]"
}
|
{
"aliases": null,
"definition": "A CD4-positive, CD8-negative thymocyte that expresses high levels of the alpha-beta T cell receptor and is CD69-positive.",
"id": "CD69Positive_CD4PositiveSinglePositiveThymocyte",
"label": "CD69-positive, CD4-positive single-positive thymocyte",
"logical_definition": null,
"original_id": "CL:0002433",
"relationships": [
{
"predicate": "DevelopsFrom",
"target": "CD4Positive_CD8IntermediateDoublePositiveThymocyte"
},
{
"predicate": "subClassOf",
"target": "CD4Positive_alphaBetaThymocyte"
}
]
}
| 0 |
{
"document": "CD69-positive, CD4-positive single-positive thymocyte A CD4-positive, CD8-negative thymocyte that expresses high levels of the alpha-beta T cell receptor and is CD69-positive. [{'predicate': 'DevelopsFrom', 'target': 'CD4Positive_CD8IntermediateDoublePositiveThymocyte'}, {'predicate': 'subClassOf', 'target': 'CD4Positive_alphaBetaThymocyte'}]"
}
|
{
"aliases": null,
"definition": "A CD8-positive, CD4-negative thymocyte that expresses high levels of the alpha-beta T cell receptor and is CD69-positive.",
"id": "CD69Positive_CD8PositiveSinglePositiveThymocyte",
"label": "CD69-positive, CD8-positive single-positive thymocyte",
"logical_definition": null,
"original_id": "CL:0002435",
"relationships": [
{
"predicate": "DevelopsFrom",
"target": "CD4Intermediate_CD8PositiveDoublePositiveThymocyte"
},
{
"predicate": "subClassOf",
"target": "CD8Positive_alphaBetaThymocyte"
}
]
}
| 0 |
{
"document": "CD69-positive, CD8-positive single-positive thymocyte A CD8-positive, CD4-negative thymocyte that expresses high levels of the alpha-beta T cell receptor and is CD69-positive. [{'predicate': 'DevelopsFrom', 'target': 'CD4Intermediate_CD8PositiveDoublePositiveThymocyte'}, {'predicate': 'subClassOf', 'target': 'CD8Positive_alphaBetaThymocyte'}]"
}
|
{
"aliases": null,
"definition": "A polychromatiic erythroblast that is Gly-A-positive and CD71-low.",
"id": "CD71Low_GlyAPositivePolychromaticErythroblast",
"label": "CD71-low, GlyA-positive polychromatic erythroblast",
"logical_definition": null,
"original_id": "CL:0002016",
"relationships": [
{
"predicate": "DevelopsFrom",
"target": "GlyAPositiveBasophilicErythroblast"
},
{
"predicate": "subClassOf",
"target": "PolychromatophilicErythroblast"
}
]
}
| 0 |
{
"document": "CD71-low, GlyA-positive polychromatic erythroblast A polychromatiic erythroblast that is Gly-A-positive and CD71-low. [{'predicate': 'DevelopsFrom', 'target': 'GlyAPositiveBasophilicErythroblast'}, {'predicate': 'subClassOf', 'target': 'PolychromatophilicErythroblast'}]"
}
|
{
"aliases": null,
"definition": "An erythroblast that is GlyA-positive and CD71-negative.",
"id": "CD71Negative_GlyAPositiveOrthochromaticErythroblast",
"label": "CD71-negative, GlyA-positive orthochromatic erythroblast",
"logical_definition": null,
"original_id": "CL:0002018",
"relationships": [
{
"predicate": "DevelopsFrom",
"target": "CD71Low_GlyAPositivePolychromaticErythroblast"
},
{
"predicate": "subClassOf",
"target": "OrthochromaticErythroblast"
}
]
}
| 0 |
{
"document": "CD71-negative, GlyA-positive orthochromatic erythroblast An erythroblast that is GlyA-positive and CD71-negative. [{'predicate': 'DevelopsFrom', 'target': 'CD71Low_GlyAPositivePolychromaticErythroblast'}, {'predicate': 'subClassOf', 'target': 'OrthochromaticErythroblast'}]"
}
|
{
"aliases": null,
"definition": "A protein that is a translation product of the human CD7 gene or a 1:1 ortholog thereof.",
"id": "CD7Molecule",
"label": "CD7 molecule",
"logical_definition": null,
"original_id": "PR:000001836",
"relationships": [
{
"predicate": "subClassOf",
"target": "Protein_PR:000000001"
}
]
}
| 0 |
{
"document": "CD7 molecule A protein that is a translation product of the human CD7 gene or a 1:1 ortholog thereof. [{'predicate': 'subClassOf', 'target': 'Protein_PR:000000001'}]"
}
|
{
"aliases": null,
"definition": "CD7-negative lymphoid progenitor cell is a lymphoid progenitor cell that is CD34-positive, CD7-negative and CD45RA-negative.",
"id": "CD7NegativeLymphoidProgenitorCell",
"label": "CD7-negative lymphoid progenitor cell",
"logical_definition": null,
"original_id": "CL:0001027",
"relationships": [
{
"predicate": "DevelopsFrom",
"target": "CD34Positive_CD38PositiveCommonLymphoidProgenitor"
},
{
"predicate": "subClassOf",
"target": "CommonLymphoidProgenitor"
}
]
}
| 0 |
{
"document": "CD7-negative lymphoid progenitor cell CD7-negative lymphoid progenitor cell is a lymphoid progenitor cell that is CD34-positive, CD7-negative and CD45RA-negative. [{'predicate': 'DevelopsFrom', 'target': 'CD34Positive_CD38PositiveCommonLymphoidProgenitor'}, {'predicate': 'subClassOf', 'target': 'CommonLymphoidProgenitor'}]"
}
|
{
"aliases": null,
"definition": null,
"id": "CD7NegativeLymphoidProgenitorORGranulocyteMonocyteProgenitor",
"label": "CD7-negative lymphoid progenitor OR granulocyte monocyte progenitor",
"logical_definition": null,
"original_id": "CL:0001012",
"relationships": [
{
"predicate": "subClassOf",
"target": "HematopoieticOligopotentProgenitorCell_lineageNegative"
}
]
}
| 0 |
{
"document": "CD7-negative lymphoid progenitor OR granulocyte monocyte progenitor None [{'predicate': 'subClassOf', 'target': 'HematopoieticOligopotentProgenitorCell_lineageNegative'}]"
}
|
{
"aliases": null,
"definition": "CD7-positive lymphoid progenitor cell is a lymphoid progenitor cell that is CD34-positive, CD7-positive and is CD45RA-negative.",
"id": "CD7PositiveLymphoidProgenitorCell",
"label": "CD7-positive lymphoid progenitor cell",
"logical_definition": null,
"original_id": "CL:0001028",
"relationships": [
{
"predicate": "DevelopsFrom",
"target": "CD7NegativeLymphoidProgenitorCell"
},
{
"predicate": "subClassOf",
"target": "CommonLymphoidProgenitor"
}
]
}
| 0 |
{
"document": "CD7-positive lymphoid progenitor cell CD7-positive lymphoid progenitor cell is a lymphoid progenitor cell that is CD34-positive, CD7-positive and is CD45RA-negative. [{'predicate': 'DevelopsFrom', 'target': 'CD7NegativeLymphoidProgenitorCell'}, {'predicate': 'subClassOf', 'target': 'CommonLymphoidProgenitor'}]"
}
|
{
"aliases": null,
"definition": "A CD8-positive, alpha-beta T cell with the phenotype CD69-positive, CD62L-negative, CD127-negative, and CD25-positive, that secretes cytokines.",
"id": "CD8Positive_alphaBetaCytokineSecretingEffectorTCell",
"label": "CD8-positive, alpha-beta cytokine secreting effector T cell",
"logical_definition": null,
"original_id": "CL:0000908",
"relationships": [
{
"predicate": "DevelopsFrom",
"target": "ActivatedCD8Positive_alphaBetaTCell"
},
{
"predicate": "subClassOf",
"target": "CD8Positive_alphaBetaTCell"
}
]
}
| 0 |
{
"document": "CD8-positive, alpha-beta cytokine secreting effector T cell A CD8-positive, alpha-beta T cell with the phenotype CD69-positive, CD62L-negative, CD127-negative, and CD25-positive, that secretes cytokines. [{'predicate': 'DevelopsFrom', 'target': 'ActivatedCD8Positive_alphaBetaTCell'}, {'predicate': 'subClassOf', 'target': 'CD8Positive_alphaBetaTCell'}]"
}
|
{
"aliases": null,
"definition": "A CD8-positive, alpha-beta T cell that has differentiated into a memory T cell.",
"id": "CD8Positive_alphaBetaMemoryTCell",
"label": "CD8-positive, alpha-beta memory T cell",
"logical_definition": null,
"original_id": "CL:0000909",
"relationships": null
}
| 0 |
{
"document": "CD8-positive, alpha-beta memory T cell A CD8-positive, alpha-beta T cell that has differentiated into a memory T cell. None"
}
|
{
"aliases": null,
"definition": "A CD8-positive, alpha-beta T cell with memory phenotype indicated by being CD45RO and CD127-positive. This cell type is also described as being CD25-negative, CD44-high, and CD122-high.",
"id": "CD8Positive_alphaBetaMemoryTCell_CD45ROPositive",
"label": "CD8-positive, alpha-beta memory T cell, CD45RO-positive",
"logical_definition": null,
"original_id": "CL:0001203",
"relationships": [
{
"predicate": "DevelopsFrom",
"target": "ActivatedCD8Positive_alphaBetaTCell"
},
{
"predicate": "subClassOf",
"target": "CD8Positive_alphaBetaMemoryTCell"
}
]
}
| 0 |
{
"document": "CD8-positive, alpha-beta memory T cell, CD45RO-positive A CD8-positive, alpha-beta T cell with memory phenotype indicated by being CD45RO and CD127-positive. This cell type is also described as being CD25-negative, CD44-high, and CD122-high. [{'predicate': 'DevelopsFrom', 'target': 'ActivatedCD8Positive_alphaBetaTCell'}, {'predicate': 'subClassOf', 'target': 'CD8Positive_alphaBetaMemoryTCell'}]"
}
|
{
"aliases": null,
"definition": "A CD8-positive, alpha-beta T cell that regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release.",
"id": "CD8Positive_alphaBetaRegulatoryTCell",
"label": "CD8-positive, alpha-beta regulatory T cell",
"logical_definition": null,
"original_id": "CL:0000795",
"relationships": [
{
"predicate": "subClassOf",
"target": "CD8Positive_alphaBetaTCell"
}
]
}
| 0 |
{
"document": "CD8-positive, alpha-beta regulatory T cell A CD8-positive, alpha-beta T cell that regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release. [{'predicate': 'subClassOf', 'target': 'CD8Positive_alphaBetaTCell'}]"
}
|
{
"aliases": null,
"definition": "A T cell expressing an alpha-beta T cell receptor and the CD8 coreceptor.",
"id": "CD8Positive_alphaBetaTCell",
"label": "CD8-positive, alpha-beta T cell",
"logical_definition": null,
"original_id": "CL:0000625",
"relationships": [
{
"predicate": "subClassOf",
"target": "MatureAlphaBetaTCell"
}
]
}
| 0 |
{
"document": "CD8-positive, alpha-beta T cell A T cell expressing an alpha-beta T cell receptor and the CD8 coreceptor. [{'predicate': 'subClassOf', 'target': 'MatureAlphaBetaTCell'}]"
}
|
{
"aliases": null,
"definition": "An immature alpha-beta T cell that is located in the thymus and is CD8-positive and CD4-negative.",
"id": "CD8Positive_alphaBetaThymocyte",
"label": "CD8-positive, alpha-beta thymocyte",
"logical_definition": null,
"original_id": "CL:0000811",
"relationships": [
{
"predicate": "DevelopsFrom",
"target": "DoublePositive_alphaBetaThymocyte"
},
{
"predicate": "subClassOf",
"target": "ImmatureAlphaBetaTCell"
}
]
}
| 0 |
{
"document": "CD8-positive, alpha-beta thymocyte An immature alpha-beta T cell that is located in the thymus and is CD8-positive and CD4-negative. [{'predicate': 'DevelopsFrom', 'target': 'DoublePositive_alphaBetaThymocyte'}, {'predicate': 'subClassOf', 'target': 'ImmatureAlphaBetaTCell'}]"
}
|
{
"aliases": null,
"definition": "A conventional thymic dendritic cell that is CD8alpha-negative.",
"id": "CD8alphaNegativeThymicConventionalDendriticCell",
"label": "CD8alpha-negative thymic conventional dendritic cell",
"logical_definition": null,
"original_id": "CL:0002460",
"relationships": [
{
"predicate": "subClassOf",
"target": "ThymicConventionalDendriticCell"
}
]
}
| 0 |
{
"document": "CD8alpha-negative thymic conventional dendritic cell A conventional thymic dendritic cell that is CD8alpha-negative. [{'predicate': 'subClassOf', 'target': 'ThymicConventionalDendriticCell'}]"
}
|
{
"aliases": null,
"definition": "A conventional thymic dendritic cell that is CD8alpha-positive.",
"id": "CD8alphaPositiveThymicConventionalDendriticCell",
"label": "CD8alpha-positive thymic conventional dendritic cell",
"logical_definition": null,
"original_id": "CL:0002059",
"relationships": [
{
"predicate": "subClassOf",
"target": "ThymicConventionalDendriticCell"
}
]
}
| 0 |
{
"document": "CD8alpha-positive thymic conventional dendritic cell A conventional thymic dendritic cell that is CD8alpha-positive. [{'predicate': 'subClassOf', 'target': 'ThymicConventionalDendriticCell'}]"
}
|
{
"aliases": null,
"definition": "A tetraspanin that is a translation product of the human CD9 gene or a 1:1 ortholog thereof.",
"id": "CD9Molecule",
"label": "CD9 molecule",
"logical_definition": null,
"original_id": "PR:000005178",
"relationships": [
{
"predicate": "subClassOf",
"target": "Tetraspanin"
}
]
}
| 0 |
{
"document": "CD9 molecule A tetraspanin that is a translation product of the human CD9 gene or a 1:1 ortholog thereof. [{'predicate': 'subClassOf', 'target': 'Tetraspanin'}]"
}
|
{
"aliases": null,
"definition": "A megakaryocyte cell with is CD9-positive and CD41-positive.",
"id": "CD9Positive_CD41PositiveMegakaryocyteCell",
"label": "CD9-positive, CD41-positive megakaryocyte cell",
"logical_definition": null,
"original_id": "CL:0002027",
"relationships": [
{
"predicate": "DevelopsFrom",
"target": "KitPositiveMegakaryocyteProgenitorCell"
},
{
"predicate": "subClassOf",
"target": "Megakaryocyte"
}
]
}
| 0 |
{
"document": "CD9-positive, CD41-positive megakaryocyte cell A megakaryocyte cell with is CD9-positive and CD41-positive. [{'predicate': 'DevelopsFrom', 'target': 'KitPositiveMegakaryocyteProgenitorCell'}, {'predicate': 'subClassOf', 'target': 'Megakaryocyte'}]"
}
|
{
"aliases": null,
"definition": "A loss of myelin from nerve fibers in the central nervous system.",
"id": "CNSDemyelination",
"label": "CNS demyelination",
"logical_definition": null,
"original_id": "HP:0007305",
"relationships": [
{
"predicate": "subClassOf",
"target": "AbnormalCNSMyelination"
}
]
}
| 0 |
{
"document": "CNS demyelination A loss of myelin from nerve fibers in the central nervous system. [{'predicate': 'subClassOf', 'target': 'AbnormalCNSMyelination'}]"
}
|
{
"aliases": null,
"definition": "The presence of foam cells, a type of macrophage that localizes to fatty deposits on blood vessel walls, in the central nervous system.",
"id": "CNSFoamCells",
"label": "CNS foam cells",
"logical_definition": null,
"original_id": "HP:0003640",
"relationships": [
{
"predicate": "subClassOf",
"target": "FoamCells"
}
]
}
| 0 |
{
"document": "CNS foam cells The presence of foam cells, a type of macrophage that localizes to fatty deposits on blood vessel walls, in the central nervous system. [{'predicate': 'subClassOf', 'target': 'FoamCells'}]"
}
|
{
"aliases": null,
"definition": "Increased amount of myelin in the central nervous system.",
"id": "CNSHypermyelination",
"label": "CNS hypermyelination",
"logical_definition": null,
"original_id": "HP:0012754",
"relationships": [
{
"predicate": "subClassOf",
"target": "AbnormalCNSMyelination"
}
]
}
| 0 |
{
"document": "CNS hypermyelination Increased amount of myelin in the central nervous system. [{'predicate': 'subClassOf', 'target': 'AbnormalCNSMyelination'}]"
}
|
{
"aliases": null,
"definition": "Reduced amount of myelin in the central nervous system resulting from defective myelinogenesis.",
"id": "CNSHypomyelination",
"label": "CNS hypomyelination",
"logical_definition": null,
"original_id": "HP:0003429",
"relationships": [
{
"predicate": "subClassOf",
"target": "AbnormalCNSMyelination"
}
]
}
| 0 |
{
"document": "CNS hypomyelination Reduced amount of myelin in the central nervous system resulting from defective myelinogenesis. [{'predicate': 'subClassOf', 'target': 'AbnormalCNSMyelination'}]"
}
|
{
"aliases": null,
"definition": "An interneuron that has its cell body in a central nervous system.",
"id": "CNSInterneuron",
"label": "CNS interneuron",
"logical_definition": null,
"original_id": "CL:0000402",
"relationships": null
}
| 0 |
{
"document": "CNS interneuron An interneuron that has its cell body in a central nervous system. None"
}
|
{
"aliases": null,
"definition": null,
"id": "CNSNeuron_sensuVertebrata_",
"label": "CNS neuron (sensu Vertebrata)",
"logical_definition": null,
"original_id": "CL:0000117",
"relationships": [
{
"predicate": "PartOf",
"target": "CentralNervousSystem"
},
{
"predicate": "DevelopsFrom",
"target": "Neuroblast_sensuVertebrata_"
},
{
"predicate": "subClassOf",
"target": "Neuron"
}
]
}
| 0 |
{
"document": "CNS neuron (sensu Vertebrata) None [{'predicate': 'PartOf', 'target': 'CentralNervousSystem'}, {'predicate': 'DevelopsFrom', 'target': 'Neuroblast_sensuVertebrata_'}, {'predicate': 'subClassOf', 'target': 'Neuron'}]"
}
|
{
"aliases": null,
"definition": "A vasculopathy in the central nervous system (CNS) following reactivation of varicella-zoster virus due to a productive viral infection of both large and small cerebral arteries.",
"id": "CNSVasculitisWithReactivationOfVaricellaZosterVirus",
"label": "CNS vasculitis with reactivation of varicella-zoster virus",
"logical_definition": null,
"original_id": "HP:0034319",
"relationships": [
{
"predicate": "subClassOf",
"target": "UnusualVirusReactivation"
}
]
}
| 0 |
{
"document": "CNS vasculitis with reactivation of varicella-zoster virus A vasculopathy in the central nervous system (CNS) following reactivation of varicella-zoster virus due to a productive viral infection of both large and small cerebral arteries. [{'predicate': 'subClassOf', 'target': 'UnusualVirusReactivation'}]"
}
|
{
"aliases": null,
"definition": "A protein with core architecture consisting of asignal sequence, 5 Ig-like domains, followed by a transmembrane sequence, followed by a Protein tyrosine kinase domain (Pfam:PF07714). However, only 1-3 of the Ig domains are detected by the Pfam HMMs in most of the sequences. Pfam:PF00047 is most common, but other members of the Ig domain clan, Pfam:PF07679 and Pfam:PF07686 can be identified instead. The fourth Ig domain lacks the disulfide-bonded cysteines.",
"id": "CSF1PDGFReceptorTypeTyrosineProteinKinase",
"label": "CSF-1/PDGF receptor-type tyrosine-protein kinase",
"logical_definition": null,
"original_id": "PR:000001810",
"relationships": [
{
"predicate": "subClassOf",
"target": "Protein_PR:000000001"
}
]
}
| 0 |
{
"document": "CSF-1/PDGF receptor-type tyrosine-protein kinase A protein with core architecture consisting of asignal sequence, 5 Ig-like domains, followed by a transmembrane sequence, followed by a Protein tyrosine kinase domain (Pfam:PF07714). However, only 1-3 of the Ig domains are detected by the Pfam HMMs in most of the sequences. Pfam:PF00047 is most common, but other members of the Ig domain clan, Pfam:PF07679 and Pfam:PF07686 can be identified instead. The fourth Ig domain lacks the disulfide-bonded cysteines. [{'predicate': 'subClassOf', 'target': 'Protein_PR:000000001'}]"
}
|
{
"aliases": null,
"definition": "The presence of autoantibodies (immunoglobulins) in the cerebrospinal fluid (CSF) that react against the NMDA (N-methyl-D-aspartate)-type glutamate receptor.",
"id": "CSFAntiNMDAReceptorAntibodyPositivity",
"label": "CSF anti-NMDA receptor antibody positivity",
"logical_definition": null,
"original_id": "HP:0032266",
"relationships": [
{
"predicate": "subClassOf",
"target": "CSFAutoimmuneAntibodyPositivity"
}
]
}
| 0 |
{
"document": "CSF anti-NMDA receptor antibody positivity The presence of autoantibodies (immunoglobulins) in the cerebrospinal fluid (CSF) that react against the NMDA (N-methyl-D-aspartate)-type glutamate receptor. [{'predicate': 'subClassOf', 'target': 'CSFAutoimmuneAntibodyPositivity'}]"
}
|
{
"aliases": null,
"definition": "The presence of an antibody in the cerebrospinal fluid (CSF) that is directed against the organism's own cells or tissues.",
"id": "CSFAutoimmuneAntibodyPositivity",
"label": "CSF autoimmune antibody positivity",
"logical_definition": null,
"original_id": "HP:0032265",
"relationships": [
{
"predicate": "subClassOf",
"target": "Autoimmunity"
}
]
}
| 0 |
{
"document": "CSF autoimmune antibody positivity The presence of an antibody in the cerebrospinal fluid (CSF) that is directed against the organism's own cells or tissues. [{'predicate': 'subClassOf', 'target': 'Autoimmunity'}]"
}
|
{
"aliases": null,
"definition": "The presence of an infectious agent in the cerebrospinal fluid (CSF).",
"id": "CSFInfectiousAgent",
"label": "CSF infectious agent",
"logical_definition": null,
"original_id": "HP:0034747",
"relationships": [
{
"predicate": "subClassOf",
"target": "AbnormalCerebrospinalFluidMorphology"
}
]
}
| 0 |
{
"document": "CSF infectious agent The presence of an infectious agent in the cerebrospinal fluid (CSF). [{'predicate': 'subClassOf', 'target': 'AbnormalCerebrospinalFluidMorphology'}]"
}
|
{
"aliases": null,
"definition": "An increased lymphocyte count in the cerebrospinal fluid.",
"id": "CSFLymphocyticPleiocytosis",
"label": "CSF lymphocytic pleiocytosis",
"logical_definition": null,
"original_id": "HP:0200149",
"relationships": [
{
"predicate": "subClassOf",
"target": "CSFPleocytosis"
}
]
}
| 0 |
{
"document": "CSF lymphocytic pleiocytosis An increased lymphocyte count in the cerebrospinal fluid. [{'predicate': 'subClassOf', 'target': 'CSFPleocytosis'}]"
}
|
{
"aliases": null,
"definition": "Mycobacterium present in the cerebrospinal fluid (CSF). This feature can be ascertained by CSF microscopy.",
"id": "CSFMycobacteria",
"label": "CSF mycobacteria",
"logical_definition": null,
"original_id": "HP:0034748",
"relationships": [
{
"predicate": "subClassOf",
"target": "BacteriaInCerebrospinalFluid"
}
]
}
| 0 |
{
"document": "CSF mycobacteria Mycobacterium present in the cerebrospinal fluid (CSF). This feature can be ascertained by CSF microscopy. [{'predicate': 'subClassOf', 'target': 'BacteriaInCerebrospinalFluid'}]"
}
|
{
"aliases": null,
"definition": "An increased white blood cell count in the cerebrospinal fluid.",
"id": "CSFPleocytosis",
"label": "CSF pleocytosis",
"logical_definition": null,
"original_id": "HP:0012229",
"relationships": [
{
"predicate": "subClassOf",
"target": "AbnormalCerebrospinalFluidMorphology"
}
]
}
| 0 |
{
"document": "CSF pleocytosis An increased white blood cell count in the cerebrospinal fluid. [{'predicate': 'subClassOf', 'target': 'AbnormalCerebrospinalFluidMorphology'}]"
}
|
{
"aliases": null,
"definition": "An increased polymorphonuclear cell count in the cerebrospinal fluid.",
"id": "CSFPolymorphonuclearPleocytosis",
"label": "CSF polymorphonuclear pleocytosis",
"logical_definition": null,
"original_id": "HP:0012756",
"relationships": [
{
"predicate": "subClassOf",
"target": "CSFPleocytosis"
}
]
}
| 0 |
{
"document": "CSF polymorphonuclear pleocytosis An increased polymorphonuclear cell count in the cerebrospinal fluid. [{'predicate': 'subClassOf', 'target': 'CSFPleocytosis'}]"
}
|
{
"aliases": null,
"definition": "A protein that is a translation product of the human CD207 gene or a 1:1 ortholog thereof.",
"id": "CTypeLectinDomainFamily4MemberK",
"label": "C-type lectin domain family 4 member K",
"logical_definition": null,
"original_id": "PR:000001293",
"relationships": [
{
"predicate": "subClassOf",
"target": "Protein_PR:000000001"
}
]
}
| 0 |
{
"document": "C-type lectin domain family 4 member K A protein that is a translation product of the human CD207 gene or a 1:1 ortholog thereof. [{'predicate': 'subClassOf', 'target': 'Protein_PR:000000001'}]"
}
|
{
"aliases": null,
"definition": "A chemokine receptor that is a translation product of the human CX3CR1 gene or a 1:1 ortholog thereof. The preferred ligand is CX3CL1.",
"id": "CX3CChemokineReceptor1",
"label": "CX3C chemokine receptor 1",
"logical_definition": null,
"original_id": "PR:000001206",
"relationships": [
{
"predicate": "subClassOf",
"target": "ChemokineReceptor"
}
]
}
| 0 |
{
"document": "CX3C chemokine receptor 1 A chemokine receptor that is a translation product of the human CX3CR1 gene or a 1:1 ortholog thereof. The preferred ligand is CX3CL1. [{'predicate': 'subClassOf', 'target': 'ChemokineReceptor'}]"
}
|
{
"aliases": null,
"definition": "Severe weight loss, wasting of muscle, loss of appetite, and general debility related to a chronic disease.",
"id": "Cachexia",
"label": "Cachexia",
"logical_definition": null,
"original_id": "HP:0004326",
"relationships": [
{
"predicate": "subClassOf",
"target": "WeightLoss"
}
]
}
| 0 |
{
"document": "Cachexia Severe weight loss, wasting of muscle, loss of appetite, and general debility related to a chronic disease. [{'predicate': 'subClassOf', 'target': 'WeightLoss'}]"
}
|
{
"aliases": null,
"definition": "A protein that has a core domain structure of signal sequence, propeptide, five Cadherin domains (Pfam:PF00028), a transmembrane region, and a Cadherin cytoplasmic region (Pfam:PF01049). Cadherins function as adhesion molecules that mediate Ca2+-dependent cell-cell adhesion in solid tissues.",
"id": "Cadherin",
"label": "cadherin",
"logical_definition": null,
"original_id": "PR:000001327",
"relationships": [
{
"predicate": "subClassOf",
"target": "Protein_PR:000000001"
}
]
}
| 0 |
{
"document": "cadherin A protein that has a core domain structure of signal sequence, propeptide, five Cadherin domains (Pfam:PF00028), a transmembrane region, and a Cadherin cytoplasmic region (Pfam:PF01049). Cadherins function as adhesion molecules that mediate Ca2+-dependent cell-cell adhesion in solid tissues. [{'predicate': 'subClassOf', 'target': 'Protein_PR:000000001'}]"
}
|
{
"aliases": null,
"definition": "A cadherin that is a translation product of the human CDH5 gene or a 1:1 ortholog thereof.",
"id": "Cadherin5",
"label": "cadherin-5",
"logical_definition": null,
"original_id": "PR:000001444",
"relationships": [
{
"predicate": "subClassOf",
"target": "Cadherin"
}
]
}
| 0 |
{
"document": "cadherin-5 A cadherin that is a translation product of the human CDH5 gene or a 1:1 ortholog thereof. [{'predicate': 'subClassOf', 'target': 'Cadherin'}]"
}
|
{
"aliases": null,
"definition": "A nematode metabolite produced by Caenorhabditis elegans.",
"id": "CaenorhabditisElegansMetabolite",
"label": "Caenorhabditis elegans metabolite",
"logical_definition": null,
"original_id": "CHEBI:78804",
"relationships": [
{
"predicate": "subClassOf",
"target": "NematodeMetabolite"
}
]
}
| 0 |
{
"document": "Caenorhabditis elegans metabolite A nematode metabolite produced by Caenorhabditis elegans. [{'predicate': 'subClassOf', 'target': 'NematodeMetabolite'}]"
}
|
{
"aliases": null,
"definition": "Delivery of a fetus through surgical incisions made through the abdominal wall (laparotomy) and the uterine wall (hysterotomy).",
"id": "CaesarianSection",
"label": "Caesarian section",
"logical_definition": null,
"original_id": "HP:0011410",
"relationships": [
{
"predicate": "subClassOf",
"target": "AbnormalDelivery"
}
]
}
| 0 |
{
"document": "Caesarian section Delivery of a fetus through surgical incisions made through the abdominal wall (laparotomy) and the uterine wall (hysterotomy). [{'predicate': 'subClassOf', 'target': 'AbnormalDelivery'}]"
}
|
{
"aliases": null,
"definition": "Cafe-au-lait spots are hyperpigmented lesions that can vary in color from light brown to dark brown with smooth borders and having a size of 1.5 cm or more in adults and 0.5 cm or more in children.",
"id": "CafeAuLaitSpot",
"label": "Cafe-au-lait spot",
"logical_definition": null,
"original_id": "HP:0000957",
"relationships": [
{
"predicate": "subClassOf",
"target": "HypermelanoticMacule"
}
]
}
| 0 |
{
"document": "Cafe-au-lait spot Cafe-au-lait spots are hyperpigmented lesions that can vary in color from light brown to dark brown with smooth borders and having a size of 1.5 cm or more in adults and 0.5 cm or more in children. [{'predicate': 'subClassOf', 'target': 'HypermelanoticMacule'}]"
}
|
{
"aliases": null,
"definition": "The presence of abnormal punctate (speckled, dot-like) calcifications in the epiphysis of the calcaneus.",
"id": "CalcanealEpiphysealStippling",
"label": "Calcaneal epiphyseal stippling",
"logical_definition": null,
"original_id": "HP:0004695",
"relationships": [
{
"predicate": "subClassOf",
"target": "EpiphysealStippling"
}
]
}
| 0 |
{
"document": "Calcaneal epiphyseal stippling The presence of abnormal punctate (speckled, dot-like) calcifications in the epiphysis of the calcaneus. [{'predicate': 'subClassOf', 'target': 'EpiphysealStippling'}]"
}
|
{
"aliases": null,
"definition": "The Achilles tendon is a tendon of the posterior leg. It serves to attach the plantaris, gastrocnemius (calf) and soleus muscles to the calcaneus (heel) bone.",
"id": "CalcanealTendon",
"label": "calcaneal tendon",
"logical_definition": null,
"original_id": "UBERON:0003701",
"relationships": [
{
"predicate": "PartOf",
"target": "TricepsSurae"
},
{
"predicate": "Connects",
"target": "MuscleOfLeg"
},
{
"predicate": "subClassOf",
"target": "Tendon"
}
]
}
| 0 |
{
"document": "calcaneal tendon The Achilles tendon is a tendon of the posterior leg. It serves to attach the plantaris, gastrocnemius (calf) and soleus muscles to the calcaneus (heel) bone. [{'predicate': 'PartOf', 'target': 'TricepsSurae'}, {'predicate': 'Connects', 'target': 'MuscleOfLeg'}, {'predicate': 'subClassOf', 'target': 'Tendon'}]"
}
|
{
"aliases": null,
"definition": "Calcaneocuboid Articulation (articulation of the calcaneus with the cuboid). The ligaments connecting the calcaneus with the cuboid are five in number, viz. , the articular capsule, the dorsal calcaneocuboid, part of the bifurcated, the long plantar, and the plantar calcaneocuboid.",
"id": "CalcaneocuboidJoint",
"label": "calcaneocuboid joint",
"logical_definition": null,
"original_id": "UBERON:0011964",
"relationships": [
{
"predicate": "PartOf",
"target": "TransverseTarsalJoint"
}
]
}
| 0 |
{
"document": "calcaneocuboid joint Calcaneocuboid Articulation (articulation of the calcaneus with the cuboid). The ligaments connecting the calcaneus with the cuboid are five in number, viz. , the articular capsule, the dorsal calcaneocuboid, part of the bifurcated, the long plantar, and the plantar calcaneocuboid. [{'predicate': 'PartOf', 'target': 'TransverseTarsalJoint'}]"
}
|
{
"aliases": null,
"definition": "A skeletal ligament that connects the fibula to the calcaneus.",
"id": "CalcaneofibularLigament",
"label": "calcaneofibular ligament",
"logical_definition": null,
"original_id": "UBERON:0011971",
"relationships": [
{
"predicate": "PartOf",
"target": "AnkleJoint"
}
]
}
| 0 |
{
"document": "calcaneofibular ligament A skeletal ligament that connects the fibula to the calcaneus. [{'predicate': 'PartOf', 'target': 'AnkleJoint'}]"
}
|
{
"aliases": null,
"definition": "Synostosis of the calcaneus with the navicular bone.",
"id": "CalcaneonavicularFusion",
"label": "Calcaneonavicular fusion",
"logical_definition": null,
"original_id": "HP:0008122",
"relationships": [
{
"predicate": "subClassOf",
"target": "TarsalSynostosis"
}
]
}
| 0 |
{
"document": "Calcaneonavicular fusion Synostosis of the calcaneus with the navicular bone. [{'predicate': 'subClassOf', 'target': 'TarsalSynostosis'}]"
}
|
{
"aliases": null,
"definition": "This is a postural deformity in which the foot is positioned up against the tibia. The heel (calcaneus) is positioned downward (that is, the ankle is flexed upward), and the heel is turned outward (valgus).",
"id": "CalcaneovalgusDeformity",
"label": "Calcaneovalgus deformity",
"logical_definition": null,
"original_id": "HP:0001848",
"relationships": [
{
"predicate": "subClassOf",
"target": "DeformedTarsalBones"
},
{
"predicate": "subClassOf",
"target": "AbnormalityOfTheCalcaneus"
}
]
}
| 0 |
{
"document": "Calcaneovalgus deformity This is a postural deformity in which the foot is positioned up against the tibia. The heel (calcaneus) is positioned downward (that is, the ankle is flexed upward), and the heel is turned outward (valgus). [{'predicate': 'subClassOf', 'target': 'DeformedTarsalBones'}, {'predicate': 'subClassOf', 'target': 'AbnormalityOfTheCalcaneus'}]"
}
|
{
"aliases": null,
"definition": "A calcaneum endochondral element that is composed primarily of cartilage tissue.",
"id": "CalcaneumCartilageElement",
"label": "calcaneum cartilage element",
"logical_definition": null,
"original_id": "UBERON:0010842",
"relationships": [
{
"predicate": "PartOf",
"target": "TarsalSkeleton"
},
{
"predicate": "DevelopsFrom",
"target": "CalcaneumPreCartilageCondensation"
},
{
"predicate": "subClassOf",
"target": "CartilaginousCondensation"
}
]
}
| 0 |
{
"document": "calcaneum cartilage element A calcaneum endochondral element that is composed primarily of cartilage tissue. [{'predicate': 'PartOf', 'target': 'TarsalSkeleton'}, {'predicate': 'DevelopsFrom', 'target': 'CalcaneumPreCartilageCondensation'}, {'predicate': 'subClassOf', 'target': 'CartilaginousCondensation'}]"
}
|
{
"aliases": null,
"definition": "A calcaneum bone or its cartilage or pre-cartilage precursor.",
"id": "CalcaneumEndochondralElement",
"label": "calcaneum endochondral element",
"logical_definition": null,
"original_id": "UBERON:0015014",
"relationships": [
{
"predicate": "PartOf",
"target": "TarsalSkeleton"
},
{
"predicate": "subClassOf",
"target": "EndochondralElement"
}
]
}
| 0 |
{
"document": "calcaneum endochondral element A calcaneum bone or its cartilage or pre-cartilage precursor. [{'predicate': 'PartOf', 'target': 'TarsalSkeleton'}, {'predicate': 'subClassOf', 'target': 'EndochondralElement'}]"
}
|
{
"aliases": null,
"definition": "A calcaneum endochondral element that is composed primarily of a pre-cartilage condensation.",
"id": "CalcaneumPreCartilageCondensation",
"label": "calcaneum pre-cartilage condensation",
"logical_definition": null,
"original_id": "UBERON:0010801",
"relationships": [
{
"predicate": "PartOf",
"target": "TarsalSkeleton"
},
{
"predicate": "subClassOf",
"target": "PreCartilageCondensation"
}
]
}
| 0 |
{
"document": "calcaneum pre-cartilage condensation A calcaneum endochondral element that is composed primarily of a pre-cartilage condensation. [{'predicate': 'PartOf', 'target': 'TarsalSkeleton'}, {'predicate': 'subClassOf', 'target': 'PreCartilageCondensation'}]"
}
|
{
"aliases": null,
"definition": "The postaxial bone of the proximal tarsals series[Phenoscape].",
"id": "Calcaneus",
"label": "calcaneus",
"logical_definition": null,
"original_id": "UBERON:0001450",
"relationships": [
{
"predicate": "PostaxialmostPartOf",
"target": "TarsalSkeleton"
},
{
"predicate": "DevelopsFrom",
"target": "CalcaneumCartilageElement"
},
{
"predicate": "subClassOf",
"target": "ProximalTarsalBone"
}
]
}
| 0 |
{
"document": "calcaneus The postaxial bone of the proximal tarsals series[Phenoscape]. [{'predicate': 'PostaxialmostPartOf', 'target': 'TarsalSkeleton'}, {'predicate': 'DevelopsFrom', 'target': 'CalcaneumCartilageElement'}, {'predicate': 'subClassOf', 'target': 'ProximalTarsalBone'}]"
}
|
{
"aliases": null,
"definition": "Skeletal element within the mouth (or in some species, upper part of the digestive tract) that is composed of dentine and is used in procuring or masticating food.",
"id": "CalcareousTooth",
"label": "calcareous tooth",
"logical_definition": null,
"original_id": "UBERON:0001091",
"relationships": [
{
"predicate": "HasPart",
"target": "Dentine"
},
{
"predicate": "HasDevelopmentalContributionFrom",
"target": "Stomodeum"
},
{
"predicate": "HasDevelopmentalContributionFrom",
"target": "ToothEnamelOrgan"
},
{
"predicate": "ImmediateTransformationOf",
"target": "ToothBud"
},
{
"predicate": "subClassOf",
"target": "ToothLikeStructure"
}
]
}
| 0 |
{
"document": "calcareous tooth Skeletal element within the mouth (or in some species, upper part of the digestive tract) that is composed of dentine and is used in procuring or masticating food. [{'predicate': 'HasPart', 'target': 'Dentine'}, {'predicate': 'HasDevelopmentalContributionFrom', 'target': 'Stomodeum'}, {'predicate': 'HasDevelopmentalContributionFrom', 'target': 'ToothEnamelOrgan'}, {'predicate': 'ImmediateTransformationOf', 'target': 'ToothBud'}, {'predicate': 'subClassOf', 'target': 'ToothLikeStructure'}]"
}
|
{
"aliases": null,
"definition": "A hydroxycalciol that is calciol in which the hydrogen at position 25 has been replaced by a hydroxy group. A prehormone resulting from the oxidation of calciol in the liver, it is further hydroxylated in the kidney to give calcitriol, the active form of vitamin D3.",
"id": "Calcidiol",
"label": "calcidiol",
"logical_definition": null,
"original_id": "CHEBI:17933",
"relationships": [
{
"predicate": "HasRole",
"target": "Metabolite"
},
{
"predicate": "HasRole",
"target": "BoneDensityConservationAgent"
},
{
"predicate": "HasRole",
"target": "Nutraceutical"
},
{
"predicate": "HasRole",
"target": "MouseMetabolite"
},
{
"predicate": "HasRole",
"target": "HumanMetabolite"
},
{
"predicate": "subClassOf",
"target": "Diol"
},
{
"predicate": "subClassOf",
"target": "Hydroxycalciol"
},
{
"predicate": "subClassOf",
"target": "D3Vitamins"
}
]
}
| 0 |
{
"document": "calcidiol A hydroxycalciol that is calciol in which the hydrogen at position 25 has been replaced by a hydroxy group. A prehormone resulting from the oxidation of calciol in the liver, it is further hydroxylated in the kidney to give calcitriol, the active form of vitamin D3. [{'predicate': 'HasRole', 'target': 'Metabolite'}, {'predicate': 'HasRole', 'target': 'BoneDensityConservationAgent'}, {'predicate': 'HasRole', 'target': 'Nutraceutical'}, {'predicate': 'HasRole', 'target': 'MouseMetabolite'}, {'predicate': 'HasRole', 'target': 'HumanMetabolite'}, {'predicate': 'subClassOf', 'target': 'Diol'}, {'predicate': 'subClassOf', 'target': 'Hydroxycalciol'}, {'predicate': 'subClassOf', 'target': 'D3Vitamins'}]"
}
|
{
"aliases": null,
"definition": "An abnormal punctate (speckled, dot-like) pattern of calcifications in soft tissues within or surrounding bones (as observed on radiographs).",
"id": "CalcificStippling",
"label": "Calcific stippling",
"logical_definition": null,
"original_id": "HP:0002832",
"relationships": [
{
"predicate": "subClassOf",
"target": "EctopicCalcification"
}
]
}
| 0 |
{
"document": "Calcific stippling An abnormal punctate (speckled, dot-like) pattern of calcifications in soft tissues within or surrounding bones (as observed on radiographs). [{'predicate': 'subClassOf', 'target': 'EctopicCalcification'}]"
}
|
{
"aliases": null,
"definition": null,
"id": "CalcificStipplingOfInfantileCartilaginousSkeleton",
"label": "Calcific stippling of infantile cartilaginous skeleton",
"logical_definition": null,
"original_id": "HP:0005841",
"relationships": [
{
"predicate": "subClassOf",
"target": "AbnormalEnchondralOssification"
}
]
}
| 0 |
{
"document": "Calcific stippling of infantile cartilaginous skeleton None [{'predicate': 'subClassOf', 'target': 'AbnormalEnchondralOssification'}]"
}
|
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