0
dict | 1
float64 0
0
| 2
dict |
|---|---|---|
{
"aliases": null,
"definition": null,
"id": "CarbohydrateSulfate",
"label": "carbohydrate sulfate",
"logical_definition": null,
"original_id": "CHEBI:35724",
"relationships": [
{
"predicate": "subClassOf",
"target": "OrganicSulfate"
},
{
"predicate": "subClassOf",
"target": "SulfuricEster"
},
{
"predicate": "subClassOf",
"target": "CarbohydrateDerivative"
}
]
}
| 0 |
{
"document": "carbohydrate sulfate None [{'predicate': 'subClassOf', 'target': 'OrganicSulfate'}, {'predicate': 'subClassOf', 'target': 'SulfuricEster'}, {'predicate': 'subClassOf', 'target': 'CarbohydrateDerivative'}]"
}
|
{
"aliases": null,
"definition": "The process in which a carbohydrate is transported across a membrane.",
"id": "CarbohydrateTransmembraneTransport",
"label": "carbohydrate transmembrane transport",
"logical_definition": null,
"original_id": "GO:0034219",
"relationships": [
{
"predicate": "subClassOf",
"target": "CarbohydrateTransport"
},
{
"predicate": "subClassOf",
"target": "TransmembraneTransport"
}
]
}
| 0 |
{
"document": "carbohydrate transmembrane transport The process in which a carbohydrate is transported across a membrane. [{'predicate': 'subClassOf', 'target': 'CarbohydrateTransport'}, {'predicate': 'subClassOf', 'target': 'TransmembraneTransport'}]"
}
|
{
"aliases": null,
"definition": "The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are a group of organic compounds based of the general formula Cx(H2O)y.",
"id": "CarbohydrateTransport",
"label": "carbohydrate transport",
"logical_definition": null,
"original_id": "GO:0008643",
"relationships": [
{
"predicate": "subClassOf",
"target": "OrganicSubstanceTransport"
}
]
}
| 0 |
{
"document": "carbohydrate transport The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are a group of organic compounds based of the general formula Cx(H2O)y. [{'predicate': 'subClassOf', 'target': 'OrganicSubstanceTransport'}]"
}
|
{
"aliases": null,
"definition": "Any organooxygen compound that is a polyhydroxy-aldehyde or -ketone, or a compound derived from one. Carbohydrates contain only carbon, hydrogen and oxygen and usually have an empirical formula Cm(H2O)n; carbohydrate derivatives may contain other elements by substitution or condensation.",
"id": "CarbohydratesAndCarbohydrateDerivatives",
"label": "carbohydrates and carbohydrate derivatives",
"logical_definition": null,
"original_id": "CHEBI:78616",
"relationships": [
{
"predicate": "subClassOf",
"target": "OrganooxygenCompound"
}
]
}
| 0 |
{
"document": "carbohydrates and carbohydrate derivatives Any organooxygen compound that is a polyhydroxy-aldehyde or -ketone, or a compound derived from one. Carbohydrates contain only carbon, hydrogen and oxygen and usually have an empirical formula Cm(H2O)n; carbohydrate derivatives may contain other elements by substitution or condensation. [{'predicate': 'subClassOf', 'target': 'OrganooxygenCompound'}]"
}
|
{
"aliases": null,
"definition": null,
"id": "CarbonAtom",
"label": "carbon atom",
"logical_definition": null,
"original_id": "CHEBI:27594",
"relationships": [
{
"predicate": "HasRole",
"target": "Macronutrient"
},
{
"predicate": "subClassOf",
"target": "NonmetalAtom"
},
{
"predicate": "subClassOf",
"target": "CarbonGroupElementAtom"
}
]
}
| 0 |
{
"document": "carbon atom None [{'predicate': 'HasRole', 'target': 'Macronutrient'}, {'predicate': 'subClassOf', 'target': 'NonmetalAtom'}, {'predicate': 'subClassOf', 'target': 'CarbonGroupElementAtom'}]"
}
|
{
"aliases": null,
"definition": "A one-carbon compound with formula CO2 in which the carbon is attached to each oxygen atom by a double bond. A colourless, odourless gas under normal conditions, it is produced during respiration by all animals, fungi and microorganisms that depend directly or indirectly on living or decaying plants for food.",
"id": "CarbonDioxide",
"label": "carbon dioxide",
"logical_definition": null,
"original_id": "CHEBI:16526",
"relationships": [
{
"predicate": "HasRole",
"target": "VasodilatorAgent"
},
{
"predicate": "HasRole",
"target": "Anaesthetic"
},
{
"predicate": "HasRole",
"target": "Solvent"
},
{
"predicate": "HasRole",
"target": "Antagonist"
},
{
"predicate": "HasRole",
"target": "MouseMetabolite"
},
{
"predicate": "HasRole",
"target": "SaccharomycesCerevisiaeMetabolite"
},
{
"predicate": "HasRole",
"target": "GreenhouseGas"
},
{
"predicate": "HasRole",
"target": "EscherichiaColiMetabolite"
},
{
"predicate": "HasRole",
"target": "HumanMetabolite"
},
{
"predicate": "HasRole",
"target": "FoodPackagingGas"
},
{
"predicate": "HasRole",
"target": "FoodPropellant"
},
{
"predicate": "HasRole",
"target": "Refrigerant"
},
{
"predicate": "subClassOf",
"target": "GasMolecularEntity"
},
{
"predicate": "subClassOf",
"target": "CarbonOxide"
},
{
"predicate": "subClassOf",
"target": "OneCarbonCompound"
}
]
}
| 0 |
{
"document": "carbon dioxide A one-carbon compound with formula CO2 in which the carbon is attached to each oxygen atom by a double bond. A colourless, odourless gas under normal conditions, it is produced during respiration by all animals, fungi and microorganisms that depend directly or indirectly on living or decaying plants for food. [{'predicate': 'HasRole', 'target': 'VasodilatorAgent'}, {'predicate': 'HasRole', 'target': 'Anaesthetic'}, {'predicate': 'HasRole', 'target': 'Solvent'}, {'predicate': 'HasRole', 'target': 'Antagonist'}, {'predicate': 'HasRole', 'target': 'MouseMetabolite'}, {'predicate': 'HasRole', 'target': 'SaccharomycesCerevisiaeMetabolite'}, {'predicate': 'HasRole', 'target': 'GreenhouseGas'}, {'predicate': 'HasRole', 'target': 'EscherichiaColiMetabolite'}, {'predicate': 'HasRole', 'target': 'HumanMetabolite'}, {'predicate': 'HasRole', 'target': 'FoodPackagingGas'}, {'predicate': 'HasRole', 'target': 'FoodPropellant'}, {'predicate': 'HasRole', 'target': 'Refrigerant'}, {'predicate': 'subClassOf', 'target': 'GasMolecularEntity'}, {'predicate': 'subClassOf', 'target': 'CarbonOxide'}, {'predicate': 'subClassOf', 'target': 'OneCarbonCompound'}]"
}
|
{
"aliases": null,
"definition": "Any portion of gas located in a part of the respiratory system that is composed primarily of carbon dioxide.",
"id": "CarbonDioxideInRespiratorySystem",
"label": "carbon dioxide in respiratory system",
"logical_definition": null,
"original_id": "UBERON:0034948",
"relationships": null
}
| 0 |
{
"document": "carbon dioxide in respiratory system Any portion of gas located in a part of the respiratory system that is composed primarily of carbon dioxide. None"
}
|
{
"aliases": null,
"definition": null,
"id": "CarbonGroupElementAtom",
"label": "carbon group element atom",
"logical_definition": null,
"original_id": "CHEBI:33306",
"relationships": [
{
"predicate": "subClassOf",
"target": "PBlockElementAtom"
}
]
}
| 0 |
{
"document": "carbon group element atom None [{'predicate': 'subClassOf', 'target': 'PBlockElementAtom'}]"
}
|
{
"aliases": null,
"definition": null,
"id": "CarbonGroupMolecularEntity",
"label": "carbon group molecular entity",
"logical_definition": null,
"original_id": "CHEBI:33582",
"relationships": [
{
"predicate": "HasPart",
"target": "CarbonGroupElementAtom"
},
{
"predicate": "subClassOf",
"target": "PBlockMolecularEntity"
}
]
}
| 0 |
{
"document": "carbon group molecular entity None [{'predicate': 'HasPart', 'target': 'CarbonGroupElementAtom'}, {'predicate': 'subClassOf', 'target': 'PBlockMolecularEntity'}]"
}
|
{
"aliases": null,
"definition": null,
"id": "CarbonOxide",
"label": "carbon oxide",
"logical_definition": null,
"original_id": "CHEBI:23014",
"relationships": [
{
"predicate": "subClassOf",
"target": "OrganicOxide"
},
{
"predicate": "subClassOf",
"target": "OrganooxygenCompound"
}
]
}
| 0 |
{
"document": "carbon oxide None [{'predicate': 'subClassOf', 'target': 'OrganicOxide'}, {'predicate': 'subClassOf', 'target': 'OrganooxygenCompound'}]"
}
|
{
"aliases": null,
"definition": null,
"id": "CarbonOxoacid",
"label": "carbon oxoacid",
"logical_definition": null,
"original_id": "CHEBI:35605",
"relationships": [
{
"predicate": "subClassOf",
"target": "Oxoacid"
},
{
"predicate": "subClassOf",
"target": "OrganooxygenCompound"
}
]
}
| 0 |
{
"document": "carbon oxoacid None [{'predicate': 'subClassOf', 'target': 'Oxoacid'}, {'predicate': 'subClassOf', 'target': 'OrganooxygenCompound'}]"
}
|
{
"aliases": null,
"definition": "A negative ion consisting solely of carbon and oxygen atoms, and therefore having the general formula CxOy(n-) for some integers x, y and n.",
"id": "CarbonOxoanion",
"label": "carbon oxoanion",
"logical_definition": null,
"original_id": "CHEBI:35604",
"relationships": [
{
"predicate": "subClassOf",
"target": "OrganicAnion"
},
{
"predicate": "subClassOf",
"target": "Oxoanion"
},
{
"predicate": "subClassOf",
"target": "OrganooxygenCompound"
}
]
}
| 0 |
{
"document": "carbon oxoanion A negative ion consisting solely of carbon and oxygen atoms, and therefore having the general formula CxOy(n-) for some integers x, y and n. [{'predicate': 'subClassOf', 'target': 'OrganicAnion'}, {'predicate': 'subClassOf', 'target': 'Oxoanion'}, {'predicate': 'subClassOf', 'target': 'OrganooxygenCompound'}]"
}
|
{
"aliases": null,
"definition": "Catalysis of the breakage of a carbon-oxygen bond.",
"id": "CarbonOxygenLyaseActivity",
"label": "carbon-oxygen lyase activity",
"logical_definition": null,
"original_id": "GO:0016835",
"relationships": [
{
"predicate": "subClassOf",
"target": "LyaseActivity"
}
]
}
| 0 |
{
"document": "carbon-oxygen lyase activity Catalysis of the breakage of a carbon-oxygen bond. [{'predicate': 'subClassOf', 'target': 'LyaseActivity'}]"
}
|
{
"aliases": null,
"definition": null,
"id": "Carbonate",
"label": "carbonate",
"logical_definition": null,
"original_id": "CHEBI:41609",
"relationships": [
{
"predicate": "obo:chebi#is_conjugate_base_of",
"target": "Hydrogencarbonate"
},
{
"predicate": "subClassOf",
"target": "CarbonOxoanion"
}
]
}
| 0 |
{
"document": "carbonate None [{'predicate': 'obo:chebi#is_conjugate_base_of', 'target': 'Hydrogencarbonate'}, {'predicate': 'subClassOf', 'target': 'CarbonOxoanion'}]"
}
|
{
"aliases": null,
"definition": null,
"id": "CarbonicAcid",
"label": "carbonic acid",
"logical_definition": null,
"original_id": "CHEBI:28976",
"relationships": [
{
"predicate": "HasRole",
"target": "MouseMetabolite"
},
{
"predicate": "obo:chebi#is_conjugate_acid_of",
"target": "Hydrogencarbonate"
},
{
"predicate": "subClassOf",
"target": "CarbonOxoacid"
},
{
"predicate": "subClassOf",
"target": "ChalcocarbonicAcid"
}
]
}
| 0 |
{
"document": "carbonic acid None [{'predicate': 'HasRole', 'target': 'MouseMetabolite'}, {'predicate': 'obo:chebi#is_conjugate_acid_of', 'target': 'Hydrogencarbonate'}, {'predicate': 'subClassOf', 'target': 'CarbonOxoacid'}, {'predicate': 'subClassOf', 'target': 'ChalcocarbonicAcid'}]"
}
|
{
"aliases": null,
"definition": "Any compound containing the carbonyl group, C=O. The term is commonly used in the restricted sense of aldehydes and ketones, although it actually includes carboxylic acids and derivatives.",
"id": "CarbonylCompound",
"label": "carbonyl compound",
"logical_definition": null,
"original_id": "CHEBI:36586",
"relationships": [
{
"predicate": "HasPart",
"target": "CarbonylGroup"
},
{
"predicate": "subClassOf",
"target": "OrganicOxoCompound"
},
{
"predicate": "subClassOf",
"target": "OrganooxygenCompound"
}
]
}
| 0 |
{
"document": "carbonyl compound Any compound containing the carbonyl group, C=O. The term is commonly used in the restricted sense of aldehydes and ketones, although it actually includes carboxylic acids and derivatives. [{'predicate': 'HasPart', 'target': 'CarbonylGroup'}, {'predicate': 'subClassOf', 'target': 'OrganicOxoCompound'}, {'predicate': 'subClassOf', 'target': 'OrganooxygenCompound'}]"
}
|
{
"aliases": null,
"definition": null,
"id": "CarbonylGroup",
"label": "carbonyl group",
"logical_definition": null,
"original_id": "CHEBI:23019",
"relationships": [
{
"predicate": "subClassOf",
"target": "OrganodiylGroup"
}
]
}
| 0 |
{
"document": "carbonyl group None [{'predicate': 'subClassOf', 'target': 'OrganodiylGroup'}]"
}
|
{
"aliases": null,
"definition": "An amide of a carboxylic acid, having the structure RC(=O)NR2. The term is used as a suffix in systematic name formation to denote the -C(=O)NH2 group including its carbon atom.",
"id": "Carboxamide",
"label": "carboxamide",
"logical_definition": null,
"original_id": "CHEBI:37622",
"relationships": [
{
"predicate": "HasPart",
"target": "CarbamoylGroup"
},
{
"predicate": "subClassOf",
"target": "PrimaryAmide"
},
{
"predicate": "subClassOf",
"target": "OrganonitrogenCompound"
},
{
"predicate": "subClassOf",
"target": "OrganooxygenCompound"
}
]
}
| 0 |
{
"document": "carboxamide An amide of a carboxylic acid, having the structure RC(=O)NR2. The term is used as a suffix in systematic name formation to denote the -C(=O)NH2 group including its carbon atom. [{'predicate': 'HasPart', 'target': 'CarbamoylGroup'}, {'predicate': 'subClassOf', 'target': 'PrimaryAmide'}, {'predicate': 'subClassOf', 'target': 'OrganonitrogenCompound'}, {'predicate': 'subClassOf', 'target': 'OrganooxygenCompound'}]"
}
|
{
"aliases": null,
"definition": null,
"id": "CarboximidicAcid",
"label": "carboximidic acid",
"logical_definition": null,
"original_id": "CHEBI:48378",
"relationships": [
{
"predicate": "subClassOf",
"target": "OrganonitrogenCompound"
},
{
"predicate": "subClassOf",
"target": "ImidicAcid"
}
]
}
| 0 |
{
"document": "carboximidic acid None [{'predicate': 'subClassOf', 'target': 'OrganonitrogenCompound'}, {'predicate': 'subClassOf', 'target': 'ImidicAcid'}]"
}
|
{
"aliases": null,
"definition": null,
"id": "CarboxyGroup",
"label": "carboxy group",
"logical_definition": null,
"original_id": "CHEBI:46883",
"relationships": [
{
"predicate": "subClassOf",
"target": "OrganylGroup"
}
]
}
| 0 |
{
"document": "carboxy group None [{'predicate': 'subClassOf', 'target': 'OrganylGroup'}]"
}
|
{
"aliases": null,
"definition": "A carbon oxoacid acid carrying at least one -C(=O)OH group and having the structure RC(=O)OH, where R is any any monovalent functional group. Carboxylic acids are the most common type of organic acid.",
"id": "CarboxylicAcid",
"label": "carboxylic acid",
"logical_definition": null,
"original_id": "CHEBI:33575",
"relationships": [
{
"predicate": "HasPart",
"target": "CarboxyGroup"
},
{
"predicate": "obo:chebi#is_conjugate_acid_of",
"target": "CarboxylicAcidAnion"
},
{
"predicate": "subClassOf",
"target": "CarbonOxoacid"
},
{
"predicate": "subClassOf",
"target": "CarbonylCompound"
},
{
"predicate": "subClassOf",
"target": "OrganicAcid"
}
]
}
| 0 |
{
"document": "carboxylic acid A carbon oxoacid acid carrying at least one -C(=O)OH group and having the structure RC(=O)OH, where R is any any monovalent functional group. Carboxylic acids are the most common type of organic acid. [{'predicate': 'HasPart', 'target': 'CarboxyGroup'}, {'predicate': 'obo:chebi#is_conjugate_acid_of', 'target': 'CarboxylicAcidAnion'}, {'predicate': 'subClassOf', 'target': 'CarbonOxoacid'}, {'predicate': 'subClassOf', 'target': 'CarbonylCompound'}, {'predicate': 'subClassOf', 'target': 'OrganicAcid'}]"
}
|
{
"aliases": null,
"definition": "The conjugate base formed when the carboxy group of a carboxylic acid is deprotonated.",
"id": "CarboxylicAcidAnion",
"label": "carboxylic acid anion",
"logical_definition": null,
"original_id": "CHEBI:29067",
"relationships": [
{
"predicate": "obo:chebi#is_conjugate_base_of",
"target": "CarboxylicAcid"
},
{
"predicate": "subClassOf",
"target": "OrganicAnion"
},
{
"predicate": "subClassOf",
"target": "Oxoanion"
}
]
}
| 0 |
{
"document": "carboxylic acid anion The conjugate base formed when the carboxy group of a carboxylic acid is deprotonated. [{'predicate': 'obo:chebi#is_conjugate_base_of', 'target': 'CarboxylicAcid'}, {'predicate': 'subClassOf', 'target': 'OrganicAnion'}, {'predicate': 'subClassOf', 'target': 'Oxoanion'}]"
}
|
{
"aliases": null,
"definition": "The chemical reactions and pathways resulting in the formation of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups.",
"id": "CarboxylicAcidBiosyntheticProcess",
"label": "carboxylic acid biosynthetic process",
"logical_definition": null,
"original_id": "GO:0046394",
"relationships": [
{
"predicate": "subClassOf",
"target": "OrganicAcidBiosyntheticProcess"
},
{
"predicate": "subClassOf",
"target": "CarboxylicAcidMetabolicProcess"
}
]
}
| 0 |
{
"document": "carboxylic acid biosynthetic process The chemical reactions and pathways resulting in the formation of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups. [{'predicate': 'subClassOf', 'target': 'OrganicAcidBiosyntheticProcess'}, {'predicate': 'subClassOf', 'target': 'CarboxylicAcidMetabolicProcess'}]"
}
|
{
"aliases": null,
"definition": "Any dianion containing at least one carboxy group.",
"id": "CarboxylicAcidDianion",
"label": "carboxylic acid dianion",
"logical_definition": null,
"original_id": "CHEBI:38716",
"relationships": [
{
"predicate": "subClassOf",
"target": "CarboxylicAcidAnion"
}
]
}
| 0 |
{
"document": "carboxylic acid dianion Any dianion containing at least one carboxy group. [{'predicate': 'subClassOf', 'target': 'CarboxylicAcidAnion'}]"
}
|
{
"aliases": null,
"definition": "The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).",
"id": "CarboxylicAcidMetabolicProcess",
"label": "carboxylic acid metabolic process",
"logical_definition": null,
"original_id": "GO:0019752",
"relationships": [
{
"predicate": "subClassOf",
"target": "OxoacidMetabolicProcess"
}
]
}
| 0 |
{
"document": "carboxylic acid metabolic process The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-). [{'predicate': 'subClassOf', 'target': 'OxoacidMetabolicProcess'}]"
}
|
{
"aliases": null,
"definition": "The directed movement of carboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-).",
"id": "CarboxylicAcidTransport",
"label": "carboxylic acid transport",
"logical_definition": null,
"original_id": "GO:0046942",
"relationships": [
{
"predicate": "subClassOf",
"target": "OrganicAnionTransport"
},
{
"predicate": "subClassOf",
"target": "OrganicAcidTransport"
}
]
}
| 0 |
{
"document": "carboxylic acid transport The directed movement of carboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-). [{'predicate': 'subClassOf', 'target': 'OrganicAnionTransport'}, {'predicate': 'subClassOf', 'target': 'OrganicAcidTransport'}]"
}
|
{
"aliases": null,
"definition": "A trianion containing at least one carboxy group.",
"id": "CarboxylicAcidTrianion",
"label": "carboxylic acid trianion",
"logical_definition": null,
"original_id": "CHEBI:38717",
"relationships": [
{
"predicate": "subClassOf",
"target": "CarboxylicAcidAnion"
}
]
}
| 0 |
{
"document": "carboxylic acid trianion A trianion containing at least one carboxy group. [{'predicate': 'subClassOf', 'target': 'CarboxylicAcidAnion'}]"
}
|
{
"aliases": null,
"definition": "An ester of a carboxylic acid, R(1)C(=O)OR(2), where R(1) = H or organyl and R(2) = organyl.",
"id": "CarboxylicEster",
"label": "carboxylic ester",
"logical_definition": null,
"original_id": "CHEBI:33308",
"relationships": [
{
"predicate": "subClassOf",
"target": "Ester"
},
{
"predicate": "subClassOf",
"target": "CarbonylCompound"
}
]
}
| 0 |
{
"document": "carboxylic ester An ester of a carboxylic acid, R(1)C(=O)OR(2), where R(1) = H or organyl and R(2) = organyl. [{'predicate': 'subClassOf', 'target': 'Ester'}, {'predicate': 'subClassOf', 'target': 'CarbonylCompound'}]"
}
|
{
"aliases": null,
"definition": null,
"id": "CarboxymethylGroup",
"label": "carboxymethyl group",
"logical_definition": null,
"original_id": "CHEBI:41402",
"relationships": [
{
"predicate": "obo:chebi#is_substituent_group_from",
"target": "AceticAcid"
},
{
"predicate": "subClassOf",
"target": "ProteinogenicAminoAcidSideChainGroup"
}
]
}
| 0 |
{
"document": "carboxymethyl group None [{'predicate': 'obo:chebi#is_substituent_group_from', 'target': 'AceticAcid'}, {'predicate': 'subClassOf', 'target': 'ProteinogenicAminoAcidSideChainGroup'}]"
}
|
{
"aliases": null,
"definition": "A pustular lesion of the skin emerging from group of infected hair follicles, characterized by a deep location and dissecting through tissue planes. A carbuncle is larger and deeper than a furuncle.",
"id": "Carbuncle",
"label": "Carbuncle",
"logical_definition": null,
"original_id": "HP:0020084",
"relationships": [
{
"predicate": "subClassOf",
"target": "Folliculitis"
}
]
}
| 0 |
{
"document": "Carbuncle A pustular lesion of the skin emerging from group of infected hair follicles, characterized by a deep location and dissecting through tissue planes. A carbuncle is larger and deeper than a furuncle. [{'predicate': 'subClassOf', 'target': 'Folliculitis'}]"
}
|
{
"aliases": null,
"definition": "A protein that is a translation product of the human CEACAM8 gene or a 1:1 ortholog thereof.",
"id": "CarcinoembryonicAntigenRelatedCellAdhesionMolecule8",
"label": "carcinoembryonic antigen-related cell adhesion molecule 8",
"logical_definition": null,
"original_id": "PR:000001332",
"relationships": [
{
"predicate": "subClassOf",
"target": "Protein_PR:000000001"
}
]
}
| 0 |
{
"document": "carcinoembryonic antigen-related cell adhesion molecule 8 A protein that is a translation product of the human CEACAM8 gene or a 1:1 ortholog thereof. [{'predicate': 'subClassOf', 'target': 'Protein_PR:000000001'}]"
}
|
{
"aliases": null,
"definition": "A carcinoembryonic antigen-related cell adhesion molecule 8 that has been processed by proteolytic cleavage.",
"id": "CarcinoembryonicAntigenRelatedCellAdhesionMolecule8ProteolyticCleavageProduct",
"label": "carcinoembryonic antigen-related cell adhesion molecule 8 proteolytic cleavage product",
"logical_definition": null,
"original_id": "PR:000018406",
"relationships": [
{
"predicate": "OutputOf",
"target": "ProteinProcessing"
},
{
"predicate": "subClassOf",
"target": "CarcinoembryonicAntigenRelatedCellAdhesionMolecule8"
},
{
"predicate": "subClassOf",
"target": "ProteolyticCleavageProduct"
}
]
}
| 0 |
{
"document": "carcinoembryonic antigen-related cell adhesion molecule 8 proteolytic cleavage product A carcinoembryonic antigen-related cell adhesion molecule 8 that has been processed by proteolytic cleavage. [{'predicate': 'OutputOf', 'target': 'ProteinProcessing'}, {'predicate': 'subClassOf', 'target': 'CarcinoembryonicAntigenRelatedCellAdhesionMolecule8'}, {'predicate': 'subClassOf', 'target': 'ProteolyticCleavageProduct'}]"
}
|
{
"aliases": null,
"definition": "A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities.",
"id": "CarcinogenicAgent",
"label": "carcinogenic agent",
"logical_definition": null,
"original_id": "CHEBI:50903",
"relationships": [
{
"predicate": "subClassOf",
"target": "AetiopathogeneticRole"
}
]
}
| 0 |
{
"document": "carcinogenic agent A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities. [{'predicate': 'subClassOf', 'target': 'AetiopathogeneticRole'}]"
}
|
{
"aliases": null,
"definition": "A tumor formed from the endocrine (argentaffin) cells of the mucosal lining of a variety of organs including the stomach and intestine. These cells are from neuroectodermal origin.",
"id": "CarcinoidTumor",
"label": "Carcinoid tumor",
"logical_definition": null,
"original_id": "HP:0100570",
"relationships": [
{
"predicate": "subClassOf",
"target": "NeuroendocrineNeoplasm"
}
]
}
| 0 |
{
"document": "Carcinoid tumor A tumor formed from the endocrine (argentaffin) cells of the mucosal lining of a variety of organs including the stomach and intestine. These cells are from neuroectodermal origin. [{'predicate': 'subClassOf', 'target': 'NeuroendocrineNeoplasm'}]"
}
|
{
"aliases": null,
"definition": "A malignant tumor arising from epithelial cells. Carcinomas that arise from glandular epithelium are called adenocarcinomas, those that arise from squamous epithelium are called squamous cell carcinomas, and those that arise from transitional epithelium are called transitional cell carcinomas (NCI Thesaurus).",
"id": "Carcinoma",
"label": "Carcinoma",
"logical_definition": null,
"original_id": "HP:0030731",
"relationships": [
{
"predicate": "subClassOf",
"target": "EpithelialNeoplasm"
}
]
}
| 0 |
{
"document": "Carcinoma A malignant tumor arising from epithelial cells. Carcinomas that arise from glandular epithelium are called adenocarcinomas, those that arise from squamous epithelium are called squamous cell carcinomas, and those that arise from transitional epithelium are called transitional cell carcinomas (NCI Thesaurus). [{'predicate': 'subClassOf', 'target': 'EpithelialNeoplasm'}]"
}
|
{
"aliases": null,
"definition": "Extracellular deposition in cardiac tissue of a proteinaceous material that, when stained with Congo red, demonstrates apple-green birefringence under polarized light and that has a distinct color when stained with sulfated Alcian blue. Viewed with electron microscopy, the amyloid deposits are seen to be composed of a beta-sheet fibrillar material. These nonbranching fibrils have a diameter of 7.5 to 10 nm and are the result of protein misfolding.",
"id": "CardiacAmyloidosis",
"label": "Cardiac amyloidosis",
"logical_definition": null,
"original_id": "HP:0030843",
"relationships": [
{
"predicate": "subClassOf",
"target": "AbnormalMyocardiumMorphology"
},
{
"predicate": "subClassOf",
"target": "Amyloidosis"
}
]
}
| 0 |
{
"document": "Cardiac amyloidosis Extracellular deposition in cardiac tissue of a proteinaceous material that, when stained with Congo red, demonstrates apple-green birefringence under polarized light and that has a distinct color when stained with sulfated Alcian blue. Viewed with electron microscopy, the amyloid deposits are seen to be composed of a beta-sheet fibrillar material. These nonbranching fibrils have a diameter of 7.5 to 10 nm and are the result of protein misfolding. [{'predicate': 'subClassOf', 'target': 'AbnormalMyocardiumMorphology'}, {'predicate': 'subClassOf', 'target': 'Amyloidosis'}]"
}
|
{
"aliases": null,
"definition": "An abrupt loss of heart function.",
"id": "CardiacArrest",
"label": "Cardiac arrest",
"logical_definition": null,
"original_id": "HP:0001695",
"relationships": [
{
"predicate": "subClassOf",
"target": "Arrhythmia"
}
]
}
| 0 |
{
"document": "Cardiac arrest An abrupt loss of heart function. [{'predicate': 'subClassOf', 'target': 'Arrhythmia'}]"
}
|
{
"aliases": null,
"definition": "Cardiac chamber in which blood enters the heart.",
"id": "CardiacAtrium",
"label": "cardiac atrium",
"logical_definition": null,
"original_id": "UBERON:0002081",
"relationships": [
{
"predicate": "ContributesToMorphologyOf",
"target": "Heart"
},
{
"predicate": "ImmediateTransformationOf",
"target": "FutureCardiacAtrium"
},
{
"predicate": "subClassOf",
"target": "CardiacChamber"
}
]
}
| 0 |
{
"document": "cardiac atrium Cardiac chamber in which blood enters the heart. [{'predicate': 'ContributesToMorphologyOf', 'target': 'Heart'}, {'predicate': 'ImmediateTransformationOf', 'target': 'FutureCardiacAtrium'}, {'predicate': 'subClassOf', 'target': 'CardiacChamber'}]"
}
|
{
"aliases": null,
"definition": "Any fibroblast that is part of a cardiac atrium.",
"id": "CardiacAtriumFibroblast",
"label": "cardiac atrium fibroblast",
"logical_definition": null,
"original_id": "CL:2000067",
"relationships": null
}
| 0 |
{
"document": "cardiac atrium fibroblast Any fibroblast that is part of a cardiac atrium. None"
}
|
{
"aliases": null,
"definition": null,
"id": "CardiacBloodVesselEndothelialCell",
"label": "cardiac blood vessel endothelial cell",
"logical_definition": null,
"original_id": "CL:0010006",
"relationships": null
}
| 0 |
{
"document": "cardiac blood vessel endothelial cell None None"
}
|
{
"aliases": null,
"definition": "A cardiac chamber surrounds an enclosed cavity within the heart.",
"id": "CardiacChamber",
"label": "cardiac chamber",
"logical_definition": null,
"original_id": "UBERON:0004151",
"relationships": [
{
"predicate": "PartOf",
"target": "Heart"
},
{
"predicate": "subClassOf",
"target": "OrganPart"
}
]
}
| 0 |
{
"document": "cardiac chamber A cardiac chamber surrounds an enclosed cavity within the heart. [{'predicate': 'PartOf', 'target': 'Heart'}, {'predicate': 'subClassOf', 'target': 'OrganPart'}]"
}
|
{
"aliases": null,
"definition": "Any anomaly of the progression of electrical impulses through the heart.",
"id": "CardiacConductionAbnormality",
"label": "Cardiac conduction abnormality",
"logical_definition": null,
"original_id": "HP:0031546",
"relationships": [
{
"predicate": "subClassOf",
"target": "AbnormalityOfCardiovascularSystemElectrophysiology"
}
]
}
| 0 |
{
"document": "Cardiac conduction abnormality Any anomaly of the progression of electrical impulses through the heart. [{'predicate': 'subClassOf', 'target': 'AbnormalityOfCardiovascularSystemElectrophysiology'}]"
}
|
{
"aliases": null,
"definition": "A cardiac diverticulum is a rare congenital malformation which is either fibrous or muscular.",
"id": "CardiacDiverticulum",
"label": "Cardiac diverticulum",
"logical_definition": null,
"original_id": "HP:0100571",
"relationships": [
{
"predicate": "subClassOf",
"target": "AbnormalCardiacVentricleMorphology"
}
]
}
| 0 |
{
"document": "Cardiac diverticulum A cardiac diverticulum is a rare congenital malformation which is either fibrous or muscular. [{'predicate': 'subClassOf', 'target': 'AbnormalCardiacVentricleMorphology'}]"
}
|
{
"aliases": null,
"definition": null,
"id": "CardiacEndothelialCell",
"label": "cardiac endothelial cell",
"logical_definition": null,
"original_id": "CL:0010008",
"relationships": null
}
| 0 |
{
"document": "cardiac endothelial cell None None"
}
|
{
"aliases": null,
"definition": "A fibroma of the heart.",
"id": "CardiacFibroma",
"label": "Cardiac fibroma",
"logical_definition": null,
"original_id": "HP:0010617",
"relationships": [
{
"predicate": "subClassOf",
"target": "Fibroma"
},
{
"predicate": "subClassOf",
"target": "NeoplasmOfTheHeart"
}
]
}
| 0 |
{
"document": "Cardiac fibroma A fibroma of the heart. [{'predicate': 'subClassOf', 'target': 'Fibroma'}, {'predicate': 'subClassOf', 'target': 'NeoplasmOfTheHeart'}]"
}
|
{
"aliases": null,
"definition": "Any of the parasympathetic ganglia of the cardiac plexus between the arch of the aorta and the bifurcation of the pulmonary artery.",
"id": "CardiacGanglion",
"label": "cardiac ganglion",
"logical_definition": null,
"original_id": "UBERON:0014463",
"relationships": [
{
"predicate": "PartOf",
"target": "ParasympatheticNervousSystem"
}
]
}
| 0 |
{
"document": "cardiac ganglion Any of the parasympathetic ganglia of the cardiac plexus between the arch of the aorta and the bifurcation of the pulmonary artery. [{'predicate': 'PartOf', 'target': 'ParasympatheticNervousSystem'}]"
}
|
{
"aliases": null,
"definition": null,
"id": "CardiacGlialCell",
"label": "cardiac glial cell",
"logical_definition": null,
"original_id": "CL:0010020",
"relationships": null
}
| 0 |
{
"document": "cardiac glial cell None None"
}
|
{
"aliases": null,
"definition": "Abnormal proliferation of blood vessels within the cardiac cavities attached to the endocardium.",
"id": "CardiacHemangioma",
"label": "Cardiac hemangioma",
"logical_definition": null,
"original_id": "HP:0011673",
"relationships": [
{
"predicate": "subClassOf",
"target": "VisceralHemangioma"
}
]
}
| 0 |
{
"document": "Cardiac hemangioma Abnormal proliferation of blood vessels within the cardiac cavities attached to the endocardium. [{'predicate': 'subClassOf', 'target': 'VisceralHemangioma'}]"
}
|
{
"aliases": null,
"definition": "A mesenchymal cell found in the developing heart and that develops into some part of the heart. These cells derive from intra- and extra-cardiac sources, including the endocardium, epicardium, neural crest, and second heart field.",
"id": "CardiacMesenchymalCell",
"label": "cardiac mesenchymal cell",
"logical_definition": null,
"original_id": "CL:0000569",
"relationships": [
{
"predicate": "subClassOf",
"target": "MigratoryCardiacNeuralCrestCell"
}
]
}
| 0 |
{
"document": "cardiac mesenchymal cell A mesenchymal cell found in the developing heart and that develops into some part of the heart. These cells derive from intra- and extra-cardiac sources, including the endocardium, epicardium, neural crest, and second heart field. [{'predicate': 'subClassOf', 'target': 'MigratoryCardiacNeuralCrestCell'}]"
}
|
{
"aliases": null,
"definition": "The embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the developing cardiac structures.",
"id": "CardiacMesenchyme",
"label": "cardiac mesenchyme",
"logical_definition": null,
"original_id": "UBERON:0009751",
"relationships": null
}
| 0 |
{
"document": "cardiac mesenchyme The embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the developing cardiac structures. None"
}
|
{
"aliases": null,
"definition": "Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. In mammals, the contractile fiber resembles those of skeletal muscle but are only one third as large in diameter, are richer in sarcoplasm, and contain centrally located instead of peripheral nuclei.",
"id": "CardiacMuscleCell",
"label": "cardiac muscle cell",
"logical_definition": null,
"original_id": "CL:0000746",
"relationships": [
{
"predicate": "DevelopsFrom",
"target": "CardiacMuscleMyoblast"
}
]
}
| 0 |
{
"document": "cardiac muscle cell Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. In mammals, the contractile fiber resembles those of skeletal muscle but are only one third as large in diameter, are richer in sarcoplasm, and contain centrally located instead of peripheral nuclei. [{'predicate': 'DevelopsFrom', 'target': 'CardiacMuscleMyoblast'}]"
}
|
{
"aliases": null,
"definition": "Muscle contraction of cardiac muscle tissue.",
"id": "CardiacMuscleContraction",
"label": "cardiac muscle contraction",
"logical_definition": null,
"original_id": "GO:0060048",
"relationships": [
{
"predicate": "PartOf",
"target": "HeartContraction"
},
{
"predicate": "subClassOf",
"target": "StriatedMuscleContraction"
}
]
}
| 0 |
{
"document": "cardiac muscle contraction Muscle contraction of cardiac muscle tissue. [{'predicate': 'PartOf', 'target': 'HeartContraction'}, {'predicate': 'subClassOf', 'target': 'StriatedMuscleContraction'}]"
}
|
{
"aliases": null,
"definition": "A precursor cell destined to differentiate into cardiac muscle cell.",
"id": "CardiacMuscleMyoblast",
"label": "cardiac muscle myoblast",
"logical_definition": null,
"original_id": "CL:0000513",
"relationships": [
{
"predicate": "subClassOf",
"target": "Myoblast"
}
]
}
| 0 |
{
"document": "cardiac muscle myoblast A precursor cell destined to differentiate into cardiac muscle cell. [{'predicate': 'subClassOf', 'target': 'Myoblast'}]"
}
|
{
"aliases": null,
"definition": "A portion of cardiac muscle tissue that is part of a left atrium [Automatically generated definition].",
"id": "CardiacMuscleOfLeftAtrium",
"label": "cardiac muscle of left atrium",
"logical_definition": null,
"original_id": "UBERON:0003380",
"relationships": null
}
| 0 |
{
"document": "cardiac muscle of left atrium A portion of cardiac muscle tissue that is part of a left atrium [Automatically generated definition]. None"
}
|
{
"aliases": null,
"definition": "A portion of cardiac muscle tissue that is part of a left ventricle [Automatically generated definition].",
"id": "CardiacMuscleOfLeftVentricle",
"label": "cardiac muscle of left ventricle",
"logical_definition": null,
"original_id": "UBERON:0003382",
"relationships": null
}
| 0 |
{
"document": "cardiac muscle of left ventricle A portion of cardiac muscle tissue that is part of a left ventricle [Automatically generated definition]. None"
}
|
{
"aliases": null,
"definition": "A portion of cardiac muscle tissue that is part of a right atrium [Automatically generated definition].",
"id": "CardiacMuscleOfRightAtrium",
"label": "cardiac muscle of right atrium",
"logical_definition": null,
"original_id": "UBERON:0003379",
"relationships": null
}
| 0 |
{
"document": "cardiac muscle of right atrium A portion of cardiac muscle tissue that is part of a right atrium [Automatically generated definition]. None"
}
|
{
"aliases": null,
"definition": "A portion of cardiac muscle tissue that is part of a right ventricle [Automatically generated definition].",
"id": "CardiacMuscleOfRightVentricle",
"label": "cardiac muscle of right ventricle",
"logical_definition": null,
"original_id": "UBERON:0003381",
"relationships": null
}
| 0 |
{
"document": "cardiac muscle of right ventricle A portion of cardiac muscle tissue that is part of a right ventricle [Automatically generated definition]. None"
}
|
{
"aliases": null,
"definition": "Muscle tissue composed of cardiac muscle cells, forming the muscles of the heart[ZFA,modified].",
"id": "CardiacMuscleTissue",
"label": "cardiac muscle tissue",
"logical_definition": null,
"original_id": "UBERON:0001133",
"relationships": [
{
"predicate": "PartOf",
"target": "PrimaryCirculatoryOrgan"
},
{
"predicate": "ComposedPrimarilyOf",
"target": "CardiacMuscleCell"
},
{
"predicate": "subClassOf",
"target": "VisceralStriatedMuscleTissue"
}
]
}
| 0 |
{
"document": "cardiac muscle tissue Muscle tissue composed of cardiac muscle cells, forming the muscles of the heart[ZFA,modified]. [{'predicate': 'PartOf', 'target': 'PrimaryCirculatoryOrgan'}, {'predicate': 'ComposedPrimarilyOf', 'target': 'CardiacMuscleCell'}, {'predicate': 'subClassOf', 'target': 'VisceralStriatedMuscleTissue'}]"
}
|
{
"aliases": null,
"definition": "A portion of cardiac muscle tissue that is part of an atrium [Automatically generated definition].",
"id": "CardiacMuscleTissueOfAtrium",
"label": "cardiac muscle tissue of atrium",
"logical_definition": null,
"original_id": "UBERON:0004490",
"relationships": [
{
"predicate": "PartOf",
"target": "MyocardiumOfAtrium"
}
]
}
| 0 |
{
"document": "cardiac muscle tissue of atrium A portion of cardiac muscle tissue that is part of an atrium [Automatically generated definition]. [{'predicate': 'PartOf', 'target': 'MyocardiumOfAtrium'}]"
}
|
{
"aliases": null,
"definition": "A portion of cardiac muscle tissue that is part of a cardiac septum [Automatically generated definition].",
"id": "CardiacMuscleTissueOfCardiacSeptum",
"label": "cardiac muscle tissue of cardiac septum",
"logical_definition": null,
"original_id": "UBERON:0004492",
"relationships": null
}
| 0 |
{
"document": "cardiac muscle tissue of cardiac septum A portion of cardiac muscle tissue that is part of a cardiac septum [Automatically generated definition]. None"
}
|
{
"aliases": null,
"definition": "A portion of cardiac muscle tissue that is part of a interatrial septum [Automatically generated definition].",
"id": "CardiacMuscleTissueOfInteratrialSeptum",
"label": "cardiac muscle tissue of interatrial septum",
"logical_definition": null,
"original_id": "UBERON:0004491",
"relationships": null
}
| 0 |
{
"document": "cardiac muscle tissue of interatrial septum A portion of cardiac muscle tissue that is part of a interatrial septum [Automatically generated definition]. None"
}
|
{
"aliases": null,
"definition": "A portion of cardiac muscle tissue that is part of an interventricular septum [Automatically generated definition].",
"id": "CardiacMuscleTissueOfInterventricularSeptum",
"label": "cardiac muscle tissue of interventricular septum",
"logical_definition": null,
"original_id": "UBERON:0003383",
"relationships": null
}
| 0 |
{
"document": "cardiac muscle tissue of interventricular septum A portion of cardiac muscle tissue that is part of an interventricular septum [Automatically generated definition]. None"
}
|
{
"aliases": null,
"definition": "A portion of cardiac muscle tissue that is part of a myocardium [Automatically generated definition].",
"id": "CardiacMuscleTissueOfMyocardium",
"label": "cardiac muscle tissue of myocardium",
"logical_definition": null,
"original_id": "UBERON:0004493",
"relationships": [
{
"predicate": "PartOf",
"target": "Myocardium"
}
]
}
| 0 |
{
"document": "cardiac muscle tissue of myocardium A portion of cardiac muscle tissue that is part of a myocardium [Automatically generated definition]. [{'predicate': 'PartOf', 'target': 'Myocardium'}]"
}
|
{
"aliases": null,
"definition": null,
"id": "CardiacMuscleTissueOfVentricle",
"label": "cardiac muscle tissue of ventricle",
"logical_definition": null,
"original_id": "UBERON:0018649",
"relationships": [
{
"predicate": "PartOf",
"target": "MyocardiumOfVentricle"
}
]
}
| 0 |
{
"document": "cardiac muscle tissue of ventricle None [{'predicate': 'PartOf', 'target': 'MyocardiumOfVentricle'}]"
}
|
{
"aliases": null,
"definition": null,
"id": "CardiacMyoblast",
"label": "cardiac myoblast",
"logical_definition": null,
"original_id": "CL:0010021",
"relationships": [
{
"predicate": "subClassOf",
"target": "AnimalCell"
}
]
}
| 0 |
{
"document": "cardiac myoblast None [{'predicate': 'subClassOf', 'target': 'AnimalCell'}]"
}
|
{
"aliases": null,
"definition": "A myxoma (tumor of primitive connective tissue) of the heart. Cardiac myxomas consist of stellate to plump, cytologically bland mesenchymal cells set in a myxoid stroma. Cardiac myxomas are of endocardial origin and general project from the endocardium into a cardiac chamber.",
"id": "CardiacMyxoma",
"label": "Cardiac myxoma",
"logical_definition": null,
"original_id": "HP:0011672",
"relationships": [
{
"predicate": "subClassOf",
"target": "NeoplasmOfTheHeart"
}
]
}
| 0 |
{
"document": "Cardiac myxoma A myxoma (tumor of primitive connective tissue) of the heart. Cardiac myxomas consist of stellate to plump, cytologically bland mesenchymal cells set in a myxoid stroma. Cardiac myxomas are of endocardial origin and general project from the endocardium into a cardiac chamber. [{'predicate': 'subClassOf', 'target': 'NeoplasmOfTheHeart'}]"
}
|
{
"aliases": null,
"definition": "A plexus of nerves situated at the base of the heart that innervate the heart.",
"id": "CardiacNervePlexus",
"label": "cardiac nerve plexus",
"logical_definition": null,
"original_id": "UBERON:0002008",
"relationships": null
}
| 0 |
{
"document": "cardiac nerve plexus A plexus of nerves situated at the base of the heart that innervate the heart. None"
}
|
{
"aliases": null,
"definition": "Portion of neural crest that develops from the dorsal neural tube. It overlaps the vagal neural crest and migrates to populate the pharyngeal arches 3, 4 and 6 (producing structures in the head) and to the heart, forming connective tissue that separates the great vessels of the heart. [Wikipedia].",
"id": "CardiacNeuralCrest",
"label": "cardiac neural crest",
"logical_definition": null,
"original_id": "UBERON:0000095",
"relationships": [
{
"predicate": "PartOf",
"target": "NeuralCrest"
},
{
"predicate": "Overlaps",
"target": "VagalNeuralCrest"
},
{
"predicate": "subClassOf",
"target": "Tissue"
}
]
}
| 0 |
{
"document": "cardiac neural crest Portion of neural crest that develops from the dorsal neural tube. It overlaps the vagal neural crest and migrates to populate the pharyngeal arches 3, 4 and 6 (producing structures in the head) and to the heart, forming connective tissue that separates the great vessels of the heart. [Wikipedia]. [{'predicate': 'PartOf', 'target': 'NeuralCrest'}, {'predicate': 'Overlaps', 'target': 'VagalNeuralCrest'}, {'predicate': 'subClassOf', 'target': 'Tissue'}]"
}
|
{
"aliases": null,
"definition": "A neurofibroma (benign peripheral nerve sheath tumor) localized in the heart.",
"id": "CardiacNeurofibroma",
"label": "Cardiac neurofibroma",
"logical_definition": null,
"original_id": "HP:0034763",
"relationships": [
{
"predicate": "subClassOf",
"target": "NeurofibromaByAnatomicalLocation"
}
]
}
| 0 |
{
"document": "Cardiac neurofibroma A neurofibroma (benign peripheral nerve sheath tumor) localized in the heart. [{'predicate': 'subClassOf', 'target': 'NeurofibromaByAnatomicalLocation'}]"
}
|
{
"aliases": null,
"definition": "A neuron that has its soma in the heart.",
"id": "CardiacNeuron",
"label": "cardiac neuron",
"logical_definition": null,
"original_id": "CL:0010022",
"relationships": null
}
| 0 |
{
"document": "cardiac neuron A neuron that has its soma in the heart. None"
}
|
{
"aliases": null,
"definition": "A rare and aggressive neoplasms developing mainly in the kidney but also in cerebral and extra-cerebral tissues and rarely in the heart. Histologically, rhabdoid renal and extrarenal tumors share common characteristics. The cells are polygonal, with eccentric, vesicular nuclei and prominent nucleoli, eosinophilic cytoplasmic inclusions. The tumors have an infiltrative growth pattern, necrosis, and high proliferative index. The immunohistochemistry tools of investigation facilitate differential diagnosis by showing loss of INI-1 expression, usually accompanied by germline mutations of the SMARCB1 gene. When INI-1 is still expressed in the affected tissues, a rhabdoid tumor with SMARCA4 mutations should be considered.",
"id": "CardiacRhabdoidTumor",
"label": "Cardiac rhabdoid tumor",
"logical_definition": null,
"original_id": "HP:0034559",
"relationships": [
{
"predicate": "subClassOf",
"target": "RhabdoidTumor"
}
]
}
| 0 |
{
"document": "Cardiac rhabdoid tumor A rare and aggressive neoplasms developing mainly in the kidney but also in cerebral and extra-cerebral tissues and rarely in the heart. Histologically, rhabdoid renal and extrarenal tumors share common characteristics. The cells are polygonal, with eccentric, vesicular nuclei and prominent nucleoli, eosinophilic cytoplasmic inclusions. The tumors have an infiltrative growth pattern, necrosis, and high proliferative index. The immunohistochemistry tools of investigation facilitate differential diagnosis by showing loss of INI-1 expression, usually accompanied by germline mutations of the SMARCB1 gene. When INI-1 is still expressed in the affected tissues, a rhabdoid tumor with SMARCA4 mutations should be considered. [{'predicate': 'subClassOf', 'target': 'RhabdoidTumor'}]"
}
|
{
"aliases": null,
"definition": "A benign tumor of cardiac striated muscle.",
"id": "CardiacRhabdomyoma",
"label": "Cardiac rhabdomyoma",
"logical_definition": null,
"original_id": "HP:0009729",
"relationships": [
{
"predicate": "subClassOf",
"target": "Rhabdomyoma"
},
{
"predicate": "subClassOf",
"target": "NeoplasmOfTheHeart"
}
]
}
| 0 |
{
"document": "Cardiac rhabdomyoma A benign tumor of cardiac striated muscle. [{'predicate': 'subClassOf', 'target': 'Rhabdomyoma'}, {'predicate': 'subClassOf', 'target': 'NeoplasmOfTheHeart'}]"
}
|
{
"aliases": null,
"definition": "A malignant soft tissue neoplasm that arises from the heart.",
"id": "CardiacSarcoma",
"label": "Cardiac sarcoma",
"logical_definition": null,
"original_id": "HP:0031350",
"relationships": [
{
"predicate": "subClassOf",
"target": "NeoplasmOfTheHeart"
}
]
}
| 0 |
{
"document": "Cardiac sarcoma A malignant soft tissue neoplasm that arises from the heart. [{'predicate': 'subClassOf', 'target': 'NeoplasmOfTheHeart'}]"
}
|
{
"aliases": null,
"definition": "The thin membranous structure between the two heart atria or the thick muscular structure between the two heart ventricles.",
"id": "CardiacSeptum",
"label": "cardiac septum",
"logical_definition": null,
"original_id": "UBERON:0002099",
"relationships": [
{
"predicate": "PartOf",
"target": "Heart"
},
{
"predicate": "AdjacentTo",
"target": "CardiacChamber"
},
{
"predicate": "ContributesToMorphologyOf",
"target": "Heart"
},
{
"predicate": "subClassOf",
"target": "Septum"
}
]
}
| 0 |
{
"document": "cardiac septum The thin membranous structure between the two heart atria or the thick muscular structure between the two heart ventricles. [{'predicate': 'PartOf', 'target': 'Heart'}, {'predicate': 'AdjacentTo', 'target': 'CardiacChamber'}, {'predicate': 'ContributesToMorphologyOf', 'target': 'Heart'}, {'predicate': 'subClassOf', 'target': 'Septum'}]"
}
|
{
"aliases": null,
"definition": "Any native cell that is part of a cardiac septum.",
"id": "CardiacSeptumCell",
"label": "cardiac septum cell",
"logical_definition": null,
"original_id": "CL:2000022",
"relationships": [
{
"predicate": "subClassOf",
"target": "AnimalCell"
}
]
}
| 0 |
{
"document": "cardiac septum cell Any native cell that is part of a cardiac septum. [{'predicate': 'subClassOf', 'target': 'AnimalCell'}]"
}
|
{
"aliases": null,
"definition": "Pattern of blood flow in the heart that deviates from the normal circuit of the circulatory system.",
"id": "CardiacShunt",
"label": "Cardiac shunt",
"logical_definition": null,
"original_id": "HP:0001693",
"relationships": [
{
"predicate": "subClassOf",
"target": "AbnormalityOfBloodCirculation"
}
]
}
| 0 |
{
"document": "Cardiac shunt Pattern of blood flow in the heart that deviates from the normal circuit of the circulatory system. [{'predicate': 'subClassOf', 'target': 'AbnormalityOfBloodCirculation'}]"
}
|
{
"aliases": null,
"definition": "Dense connective tissue that separates the atria from the ventricles and provides physical support for the heart.",
"id": "CardiacSkeleton",
"label": "cardiac skeleton",
"logical_definition": null,
"original_id": "UBERON:0004292",
"relationships": [
{
"predicate": "PartOf",
"target": "Heart"
},
{
"predicate": "AdjacentTo",
"target": "CardiacAtrium"
},
{
"predicate": "AdjacentTo",
"target": "CardiacVentricle"
},
{
"predicate": "subClassOf",
"target": "ConnectiveTissue"
}
]
}
| 0 |
{
"document": "cardiac skeleton Dense connective tissue that separates the atria from the ventricles and provides physical support for the heart. [{'predicate': 'PartOf', 'target': 'Heart'}, {'predicate': 'AdjacentTo', 'target': 'CardiacAtrium'}, {'predicate': 'AdjacentTo', 'target': 'CardiacVentricle'}, {'predicate': 'subClassOf', 'target': 'ConnectiveTissue'}]"
}
|
{
"aliases": null,
"definition": "The accumulation of pericardial fluid with subsequent compression of all cardiac chambers which prevents cardiac filling.",
"id": "CardiacTamponade",
"label": "Cardiac tamponade",
"logical_definition": null,
"original_id": "HP:0033415",
"relationships": [
{
"predicate": "subClassOf",
"target": "AbnormalCardiovascularSystemPhysiology"
}
]
}
| 0 |
{
"document": "Cardiac tamponade The accumulation of pericardial fluid with subsequent compression of all cardiac chambers which prevents cardiac filling. [{'predicate': 'subClassOf', 'target': 'AbnormalCardiovascularSystemPhysiology'}]"
}
|
{
"aliases": null,
"definition": "A teratoma within the heart. Most commonly, these tumors are detected in the pericardial cavity attached to the pulmonary artery and aorta. The tumor size within the heart varies from 2 to 9 cm in diameter, and intrapericardial tumors as large as 15 cm have been reported. Intracardiac tumors arise from the atrial or ventricular wall as nodular masses protruding into the cardiac chambers. Cardiac and pericardial teratomas are easily detected in the fetus and neonate by two-dimensional echocardiography as heterogeneous and encapsulated cystic masses. Histologically, cardiac teratomas contain multiple immature elements including epithelium, neuroglial tissue, thyroid, pancreas, smooth and skeletal muscle, cartilage and bone.",
"id": "CardiacTeratoma",
"label": "Cardiac teratoma",
"logical_definition": null,
"original_id": "HP:0011674",
"relationships": [
{
"predicate": "subClassOf",
"target": "Teratoma"
},
{
"predicate": "subClassOf",
"target": "NeoplasmOfTheHeart"
}
]
}
| 0 |
{
"document": "Cardiac teratoma A teratoma within the heart. Most commonly, these tumors are detected in the pericardial cavity attached to the pulmonary artery and aorta. The tumor size within the heart varies from 2 to 9 cm in diameter, and intrapericardial tumors as large as 15 cm have been reported. Intracardiac tumors arise from the atrial or ventricular wall as nodular masses protruding into the cardiac chambers. Cardiac and pericardial teratomas are easily detected in the fetus and neonate by two-dimensional echocardiography as heterogeneous and encapsulated cystic masses. Histologically, cardiac teratomas contain multiple immature elements including epithelium, neuroglial tissue, thyroid, pancreas, smooth and skeletal muscle, cartilage and bone. [{'predicate': 'subClassOf', 'target': 'Teratoma'}, {'predicate': 'subClassOf', 'target': 'NeoplasmOfTheHeart'}]"
}
|
{
"aliases": null,
"definition": "Type 2 total anomalous pulmonary venous connection.",
"id": "CardiacTotalAnomalousPulmonaryVenousConnection",
"label": "Cardiac total anomalous pulmonary venous connection",
"logical_definition": null,
"original_id": "HP:0011720",
"relationships": [
{
"predicate": "subClassOf",
"target": "TotalAnomalousPulmonaryVenousReturn"
}
]
}
| 0 |
{
"document": "Cardiac total anomalous pulmonary venous connection Type 2 total anomalous pulmonary venous connection. [{'predicate': 'subClassOf', 'target': 'TotalAnomalousPulmonaryVenousReturn'}]"
}
|
{
"aliases": null,
"definition": "A membranous fold of the heart that prevents reflux of fluid.",
"id": "CardiacValve",
"label": "cardiac valve",
"logical_definition": null,
"original_id": "UBERON:0000946",
"relationships": [
{
"predicate": "PartOf",
"target": "Heart"
},
{
"predicate": "DevelopsFrom",
"target": "EndocardialCushion"
},
{
"predicate": "subClassOf",
"target": "Valve"
}
]
}
| 0 |
{
"document": "cardiac valve A membranous fold of the heart that prevents reflux of fluid. [{'predicate': 'PartOf', 'target': 'Heart'}, {'predicate': 'DevelopsFrom', 'target': 'EndocardialCushion'}, {'predicate': 'subClassOf', 'target': 'Valve'}]"
}
|
{
"aliases": null,
"definition": "Abnormal calcification of a cardiac valve.",
"id": "CardiacValveCalcification",
"label": "Cardiac valve calcification",
"logical_definition": null,
"original_id": "HP:0005146",
"relationships": [
{
"predicate": "subClassOf",
"target": "AbnormalHeartValveMorphology"
},
{
"predicate": "subClassOf",
"target": "CardiovascularCalcification"
}
]
}
| 0 |
{
"document": "Cardiac valve calcification Abnormal calcification of a cardiac valve. [{'predicate': 'subClassOf', 'target': 'AbnormalHeartValveMorphology'}, {'predicate': 'subClassOf', 'target': 'CardiovascularCalcification'}]"
}
|
{
"aliases": null,
"definition": "A cell that is part of a cardiac valve.",
"id": "CardiacValveCell",
"label": "cardiac valve cell",
"logical_definition": null,
"original_id": "CL:1000147",
"relationships": [
{
"predicate": "subClassOf",
"target": "AnimalCell"
}
]
}
| 0 |
{
"document": "cardiac valve cell A cell that is part of a cardiac valve. [{'predicate': 'subClassOf', 'target': 'AnimalCell'}]"
}
|
{
"aliases": null,
"definition": null,
"id": "CardiacValveLeaflet",
"label": "cardiac valve leaflet",
"logical_definition": null,
"original_id": "UBERON:0011741",
"relationships": [
{
"predicate": "PartOf",
"target": "CardiacValve"
},
{
"predicate": "subClassOf",
"target": "OrganPart"
}
]
}
| 0 |
{
"document": "cardiac valve leaflet None [{'predicate': 'PartOf', 'target': 'CardiacValve'}, {'predicate': 'subClassOf', 'target': 'OrganPart'}]"
}
|
{
"aliases": null,
"definition": "Vein of heart that drains the myocardium.",
"id": "CardiacVein",
"label": "cardiac vein",
"logical_definition": null,
"original_id": "UBERON:0004148",
"relationships": [
{
"predicate": "subClassOf",
"target": "SystemicVein"
}
]
}
| 0 |
{
"document": "cardiac vein Vein of heart that drains the myocardium. [{'predicate': 'subClassOf', 'target': 'SystemicVein'}]"
}
|
{
"aliases": null,
"definition": "Cardiac chamber through which blood leaves the heart.",
"id": "CardiacVentricle",
"label": "cardiac ventricle",
"logical_definition": null,
"original_id": "UBERON:0002082",
"relationships": [
{
"predicate": "ContributesToMorphologyOf",
"target": "Heart"
},
{
"predicate": "ImmediateTransformationOf",
"target": "FutureCardiacVentricle"
},
{
"predicate": "subClassOf",
"target": "CardiacChamber"
}
]
}
| 0 |
{
"document": "cardiac ventricle Cardiac chamber through which blood leaves the heart. [{'predicate': 'ContributesToMorphologyOf', 'target': 'Heart'}, {'predicate': 'ImmediateTransformationOf', 'target': 'FutureCardiacVentricle'}, {'predicate': 'subClassOf', 'target': 'CardiacChamber'}]"
}
|
{
"aliases": null,
"definition": "Any fibroblast that is part of a cardiac ventricle.",
"id": "CardiacVentricleFibroblast",
"label": "cardiac ventricle fibroblast",
"logical_definition": null,
"original_id": "CL:2000066",
"relationships": null
}
| 0 |
{
"document": "cardiac ventricle fibroblast Any fibroblast that is part of a cardiac ventricle. None"
}
|
{
"aliases": null,
"definition": "Any of the four veins in the developing vertebrate embryo which run along each side of the vertebral column.",
"id": "CardinalVein",
"label": "cardinal vein",
"logical_definition": null,
"original_id": "UBERON:0004344",
"relationships": [
{
"predicate": "PartOf",
"target": "Embryo"
},
{
"predicate": "subClassOf",
"target": "Vein"
}
]
}
| 0 |
{
"document": "cardinal vein Any of the four veins in the developing vertebrate embryo which run along each side of the vertebral column. [{'predicate': 'PartOf', 'target': 'Embryo'}, {'predicate': 'subClassOf', 'target': 'Vein'}]"
}
|
{
"aliases": null,
"definition": "A cell located in the heart, including both muscle and non muscle cells.",
"id": "Cardiocyte",
"label": "cardiocyte",
"logical_definition": null,
"original_id": "CL:0002494",
"relationships": [
{
"predicate": "subClassOf",
"target": "AnimalCell"
},
{
"predicate": "subClassOf",
"target": "SomaticCell"
}
]
}
| 0 |
{
"document": "cardiocyte A cell located in the heart, including both muscle and non muscle cells. [{'predicate': 'subClassOf', 'target': 'AnimalCell'}, {'predicate': 'subClassOf', 'target': 'SomaticCell'}]"
}
|
{
"aliases": null,
"definition": "The first recognizable structure derived from the heart field.",
"id": "CardiogenicPlate",
"label": "cardiogenic plate",
"logical_definition": null,
"original_id": "UBERON:0004139",
"relationships": [
{
"predicate": "PartOf",
"target": "Embryo"
},
{
"predicate": "DevelopsFrom",
"target": "HeartPrimordium"
},
{
"predicate": "subClassOf",
"target": "DevelopingAnatomicalStructure"
}
]
}
| 0 |
{
"document": "cardiogenic plate The first recognizable structure derived from the heart field. [{'predicate': 'PartOf', 'target': 'Embryo'}, {'predicate': 'DevelopsFrom', 'target': 'HeartPrimordium'}, {'predicate': 'subClassOf', 'target': 'DevelopingAnatomicalStructure'}]"
}
|
{
"aliases": null,
"definition": "Severely decreased cardiac output with evidence of inadequate end-organ perfusion (i.e., tissue hypoxia) in the presence of adequate intravascular volume.",
"id": "CardiogenicShock",
"label": "Cardiogenic shock",
"logical_definition": null,
"original_id": "HP:0030149",
"relationships": [
{
"predicate": "subClassOf",
"target": "Shock"
}
]
}
| 0 |
{
"document": "Cardiogenic shock Severely decreased cardiac output with evidence of inadequate end-organ perfusion (i.e., tissue hypoxia) in the presence of adequate intravascular volume. [{'predicate': 'subClassOf', 'target': 'Shock'}]"
}
|
{
"aliases": null,
"definition": "The splanchnic mesoderm in the cardiogenic region where the heart develops; it gives rise to endocardial heart tubes that fuse to form the primordial cardiac tube, the heart primordium[web]. Two migratory heart primordia that move ventrally during the course of neurulation, and then fuse[XAO].",
"id": "CardiogenicSplanchnicMesoderm",
"label": "cardiogenic splanchnic mesoderm",
"logical_definition": null,
"original_id": "UBERON:0007005",
"relationships": [
{
"predicate": "PartOf",
"target": "PrimaryHeartField"
},
{
"predicate": "PartOf",
"target": "AnteriorLateralPlateMesoderm"
},
{
"predicate": "DevelopsFrom",
"target": "SplanchnicLayerOfLateralPlateMesoderm"
},
{
"predicate": "DevelopmentallyInducedBy",
"target": "AnteriorLateralPlateMesoderm"
},
{
"predicate": "subClassOf",
"target": "Tissue"
}
]
}
| 0 |
{
"document": "cardiogenic splanchnic mesoderm The splanchnic mesoderm in the cardiogenic region where the heart develops; it gives rise to endocardial heart tubes that fuse to form the primordial cardiac tube, the heart primordium[web]. Two migratory heart primordia that move ventrally during the course of neurulation, and then fuse[XAO]. [{'predicate': 'PartOf', 'target': 'PrimaryHeartField'}, {'predicate': 'PartOf', 'target': 'AnteriorLateralPlateMesoderm'}, {'predicate': 'DevelopsFrom', 'target': 'SplanchnicLayerOfLateralPlateMesoderm'}, {'predicate': 'DevelopmentallyInducedBy', 'target': 'AnteriorLateralPlateMesoderm'}, {'predicate': 'subClassOf', 'target': 'Tissue'}]"
}
|
{
"aliases": null,
"definition": "Increased size of the heart, clinically defined as an increased transverse diameter of the cardiac silhouette that is greater than or equal to 50% of the transverse diameter of the chest (increased cardiothoracic ratio) on a posterior-anterior projection of a chest radiograph or a computed tomography.",
"id": "Cardiomegaly",
"label": "Cardiomegaly",
"logical_definition": null,
"original_id": "HP:0001640",
"relationships": [
{
"predicate": "subClassOf",
"target": "AbnormalHeartMorphology"
}
]
}
| 0 |
{
"document": "Cardiomegaly Increased size of the heart, clinically defined as an increased transverse diameter of the cardiac silhouette that is greater than or equal to 50% of the transverse diameter of the chest (increased cardiothoracic ratio) on a posterior-anterior projection of a chest radiograph or a computed tomography. [{'predicate': 'subClassOf', 'target': 'AbnormalHeartMorphology'}]"
}
|
{
"aliases": null,
"definition": "Deterioration of cardiomyocyte characterized by abnormal features such as loss of myofilaments, occurrence of cellular sequestration, decreased mitochondrial sizes and cellular debris.",
"id": "CardiomyocyteDegeneration",
"label": "Cardiomyocyte degeneration",
"logical_definition": null,
"original_id": "HP:0031332",
"relationships": [
{
"predicate": "subClassOf",
"target": "AbnormalCardiomyocyteMorphology"
}
]
}
| 0 |
{
"document": "Cardiomyocyte degeneration Deterioration of cardiomyocyte characterized by abnormal features such as loss of myofilaments, occurrence of cellular sequestration, decreased mitochondrial sizes and cellular debris. [{'predicate': 'subClassOf', 'target': 'AbnormalCardiomyocyteMorphology'}]"
}
|
{
"aliases": null,
"definition": "An increase in cell size, enhanced protein synthesis, and heightened organization of the sarcomere within cardiac myocytes.",
"id": "CardiomyocyteHypertrophy",
"label": "Cardiomyocyte hypertrophy",
"logical_definition": null,
"original_id": "HP:0031319",
"relationships": [
{
"predicate": "subClassOf",
"target": "AbnormalCardiomyocyteMorphology"
}
]
}
| 0 |
{
"document": "Cardiomyocyte hypertrophy An increase in cell size, enhanced protein synthesis, and heightened organization of the sarcomere within cardiac myocytes. [{'predicate': 'subClassOf', 'target': 'AbnormalCardiomyocyteMorphology'}]"
}
|
{
"aliases": null,
"definition": "Nuclear or cytoplasmic aggregates of stainable substances within cardiomyocytes.",
"id": "CardiomyocyteInclusionBodies",
"label": "Cardiomyocyte inclusion bodies",
"logical_definition": null,
"original_id": "HP:0031334",
"relationships": [
{
"predicate": "subClassOf",
"target": "AbnormalCardiomyocyteMorphology"
}
]
}
| 0 |
{
"document": "Cardiomyocyte inclusion bodies Nuclear or cytoplasmic aggregates of stainable substances within cardiomyocytes. [{'predicate': 'subClassOf', 'target': 'AbnormalCardiomyocyteMorphology'}]"
}
|
{
"aliases": null,
"definition": "An abnormal increase in the number of mitochondria per cardiac myocyte.",
"id": "CardiomyocyteMitochondrialProliferation",
"label": "Cardiomyocyte mitochondrial proliferation",
"logical_definition": null,
"original_id": "HP:0031320",
"relationships": [
{
"predicate": "subClassOf",
"target": "AbnormalCardiomyocyteMorphology"
}
]
}
| 0 |
{
"document": "Cardiomyocyte mitochondrial proliferation An abnormal increase in the number of mitochondria per cardiac myocyte. [{'predicate': 'subClassOf', 'target': 'AbnormalCardiomyocyteMorphology'}]"
}
|
{
"aliases": null,
"definition": "A myocardial disorder in which the heart muscle is structurally and functionally abnormal, in the absence of coronary artery disease, hypertension, valvular disease and congenital heart disease sufficient to cause the observed myocardial abnormality.",
"id": "Cardiomyopathy",
"label": "Cardiomyopathy",
"logical_definition": null,
"original_id": "HP:0001638",
"relationships": [
{
"predicate": "subClassOf",
"target": "AbnormalMyocardiumMorphology"
}
]
}
| 0 |
{
"document": "Cardiomyopathy A myocardial disorder in which the heart muscle is structurally and functionally abnormal, in the absence of coronary artery disease, hypertension, valvular disease and congenital heart disease sufficient to cause the observed myocardial abnormality. [{'predicate': 'subClassOf', 'target': 'AbnormalMyocardiumMorphology'}]"
}
|
{
"aliases": null,
"definition": "An region of the mesoderm that includes anterior lateral mesoderm of the first heart field plus contiguous pharyngeal mesoderm that gives rise to second-heart-field-derived regions of the heart and branchiomeric muscles.",
"id": "CardiopharyngealField",
"label": "cardiopharyngeal field",
"logical_definition": null,
"original_id": "UBERON:0036146",
"relationships": [
{
"predicate": "PartOf",
"target": "Embryo"
},
{
"predicate": "DevelopsFrom",
"target": "Mesoderm"
},
{
"predicate": "subClassOf",
"target": "Anlage"
}
]
}
| 0 |
{
"document": "cardiopharyngeal field An region of the mesoderm that includes anterior lateral mesoderm of the first heart field plus contiguous pharyngeal mesoderm that gives rise to second-heart-field-derived regions of the heart and branchiomeric muscles. [{'predicate': 'PartOf', 'target': 'Embryo'}, {'predicate': 'DevelopsFrom', 'target': 'Mesoderm'}, {'predicate': 'subClassOf', 'target': 'Anlage'}]"
}
|
{
"aliases": null,
"definition": null,
"id": "CardiorespiratoryArrest",
"label": "Cardiorespiratory arrest",
"logical_definition": null,
"original_id": "HP:0006543",
"relationships": [
{
"predicate": "subClassOf",
"target": "RespiratoryArrest"
}
]
}
| 0 |
{
"document": "Cardiorespiratory arrest None [{'predicate': 'subClassOf', 'target': 'RespiratoryArrest'}]"
}
|
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