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{
"aliases": null,
"definition": "The process in which cellular structures, including whole cells or cell parts, are generated and organized.",
"id": "CellularComponentMorphogenesis",
"label": "cellular component morphogenesis",
"logical_definition": null,
"original_id": "GO:0032989",
"relationships": [
{
"predicate": "subClassOf",
"target": "AnatomicalStructureMorphogenesis"
},
{
"predicate": "subClassOf",
"target": "CellularComponentOrganization"
},
{
"predicate": "subClassOf",
"target": "CellularDevelopmentalProcess"
}
]
}
| 0 |
{
"document": "cellular component morphogenesis The process in which cellular structures, including whole cells or cell parts, are generated and organized. [{'predicate': 'subClassOf', 'target': 'AnatomicalStructureMorphogenesis'}, {'predicate': 'subClassOf', 'target': 'CellularComponentOrganization'}, {'predicate': 'subClassOf', 'target': 'CellularDevelopmentalProcess'}]"
}
|
{
"aliases": null,
"definition": "A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.",
"id": "CellularComponentOrganization",
"label": "cellular component organization",
"logical_definition": null,
"original_id": "GO:0016043",
"relationships": [
{
"predicate": "subClassOf",
"target": "CellularComponentOrganizationOrBiogenesis"
}
]
}
| 0 |
{
"document": "cellular component organization A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component. [{'predicate': 'subClassOf', 'target': 'CellularComponentOrganizationOrBiogenesis'}]"
}
|
{
"aliases": null,
"definition": "A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component.",
"id": "CellularComponentOrganizationOrBiogenesis",
"label": "cellular component organization or biogenesis",
"logical_definition": null,
"original_id": "GO:0071840",
"relationships": [
{
"predicate": "subClassOf",
"target": "CellularProcess"
}
]
}
| 0 |
{
"document": "cellular component organization or biogenesis A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component. [{'predicate': 'subClassOf', 'target': 'CellularProcess'}]"
}
|
{
"aliases": null,
"definition": "A type of glomerular crescent characterized by extracapillary hypercellularity of greater than two cell layers and involving more than 10% of the capsular circumference, composed of greater than 75% cells with or without fibrin, and less than 25% fibrous matrix.",
"id": "CellularCrescent",
"label": "Cellular crescent",
"logical_definition": null,
"original_id": "HP:0033317",
"relationships": [
{
"predicate": "subClassOf",
"target": "GlomerularCrescentFormation"
}
]
}
| 0 |
{
"document": "Cellular crescent A type of glomerular crescent characterized by extracapillary hypercellularity of greater than two cell layers and involving more than 10% of the capsular circumference, composed of greater than 75% cells with or without fibrin, and less than 25% fibrous matrix. [{'predicate': 'subClassOf', 'target': 'GlomerularCrescentFormation'}]"
}
|
{
"aliases": null,
"definition": "A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.",
"id": "CellularDevelopmentalProcess",
"label": "cellular developmental process",
"logical_definition": null,
"original_id": "GO:0048869",
"relationships": [
{
"predicate": "subClassOf",
"target": "CellularProcess"
},
{
"predicate": "subClassOf",
"target": "DevelopmentalProcess"
}
]
}
| 0 |
{
"document": "cellular developmental process A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition. [{'predicate': 'subClassOf', 'target': 'CellularProcess'}, {'predicate': 'subClassOf', 'target': 'DevelopmentalProcess'}]"
}
|
{
"aliases": null,
"definition": "Any process involved in the maintenance of an internal steady state at the level of the cell.",
"id": "CellularHomeostasis",
"label": "cellular homeostasis",
"logical_definition": null,
"original_id": "GO:0019725",
"relationships": [
{
"predicate": "subClassOf",
"target": "HomeostaticProcess"
}
]
}
| 0 |
{
"document": "cellular homeostasis Any process involved in the maintenance of an internal steady state at the level of the cell. [{'predicate': 'subClassOf', 'target': 'HomeostaticProcess'}]"
}
|
{
"aliases": null,
"definition": "An increased cellular sensitivity to the DNA cross-linking agent, diepoxybutane (DEB). In the presence of increased sensitivity, DEB causes cell death, chromosome breakage, and accumulation in the G2 phase of the cell cycle.",
"id": "CellularHypersensitivityToDiepoxybutane",
"label": "Cellular hypersensitivity to diepoxybutane",
"logical_definition": null,
"original_id": "HP:0032189",
"relationships": [
{
"predicate": "subClassOf",
"target": "AbnormalityOfDNARepair"
}
]
}
| 0 |
{
"document": "Cellular hypersensitivity to diepoxybutane An increased cellular sensitivity to the DNA cross-linking agent, diepoxybutane (DEB). In the presence of increased sensitivity, DEB causes cell death, chromosome breakage, and accumulation in the G2 phase of the cell cycle. [{'predicate': 'subClassOf', 'target': 'AbnormalityOfDNARepair'}]"
}
|
{
"aliases": null,
"definition": "An increased cellular sensitivity to the DNA cross-linking agent, mitomycin C (MMC). In the presence of increased sensitivity, MMC causes increased cell death, chromosome breakage, and accumulation in the G2 phase of the cell cycle.",
"id": "CellularHypersensitivityToMitomycinC",
"label": "Cellular hypersensitivity to mitomycin C",
"logical_definition": null,
"original_id": "HP:0032188",
"relationships": [
{
"predicate": "subClassOf",
"target": "AbnormalityOfDNARepair"
}
]
}
| 0 |
{
"document": "Cellular hypersensitivity to mitomycin C An increased cellular sensitivity to the DNA cross-linking agent, mitomycin C (MMC). In the presence of increased sensitivity, MMC causes increased cell death, chromosome breakage, and accumulation in the G2 phase of the cell cycle. [{'predicate': 'subClassOf', 'target': 'AbnormalityOfDNARepair'}]"
}
|
{
"aliases": null,
"definition": "An immunodeficiency characterized by defective cell-mediated immunity or humoral immunity.",
"id": "CellularImmunodeficiency",
"label": "Cellular immunodeficiency",
"logical_definition": null,
"original_id": "HP:0005374",
"relationships": [
{
"predicate": "subClassOf",
"target": "Immunodeficiency"
}
]
}
| 0 |
{
"document": "Cellular immunodeficiency An immunodeficiency characterized by defective cell-mediated immunity or humoral immunity. [{'predicate': 'subClassOf', 'target': 'Immunodeficiency'}]"
}
|
{
"aliases": null,
"definition": "The chemical reactions and pathways involving ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone, as carried out by individual cells. Although 3-hydroxybutyrate is not a ketone, it is classed as a ketone body because it exists in an equilibrium with acetoacetate. Ketone bodies may accumulate in excessive amounts in the body in starvation, diabetes mellitus or in other defects of carbohydrate metabolism.",
"id": "CellularKetoneBodyMetabolicProcess",
"label": "cellular ketone body metabolic process",
"logical_definition": null,
"original_id": "GO:0046950",
"relationships": [
{
"predicate": "subClassOf",
"target": "CellularMetabolicProcess"
},
{
"predicate": "subClassOf",
"target": "SmallMoleculeMetabolicProcess"
}
]
}
| 0 |
{
"document": "cellular ketone body metabolic process The chemical reactions and pathways involving ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone, as carried out by individual cells. Although 3-hydroxybutyrate is not a ketone, it is classed as a ketone body because it exists in an equilibrium with acetoacetate. Ketone bodies may accumulate in excessive amounts in the body in starvation, diabetes mellitus or in other defects of carbohydrate metabolism. [{'predicate': 'subClassOf', 'target': 'CellularMetabolicProcess'}, {'predicate': 'subClassOf', 'target': 'SmallMoleculeMetabolicProcess'}]"
}
|
{
"aliases": null,
"definition": "The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.",
"id": "CellularKetoneMetabolicProcess",
"label": "cellular ketone metabolic process",
"logical_definition": null,
"original_id": "GO:0042180",
"relationships": [
{
"predicate": "subClassOf",
"target": "CellularMetabolicProcess"
},
{
"predicate": "subClassOf",
"target": "SmallMoleculeMetabolicProcess"
},
{
"predicate": "subClassOf",
"target": "OrganicSubstanceMetabolicProcess"
}
]
}
| 0 |
{
"document": "cellular ketone metabolic process The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups. [{'predicate': 'subClassOf', 'target': 'CellularMetabolicProcess'}, {'predicate': 'subClassOf', 'target': 'SmallMoleculeMetabolicProcess'}, {'predicate': 'subClassOf', 'target': 'OrganicSubstanceMetabolicProcess'}]"
}
|
{
"aliases": null,
"definition": "The chemical reactions and pathways involving lipids, as carried out by individual cells.",
"id": "CellularLipidMetabolicProcess",
"label": "cellular lipid metabolic process",
"logical_definition": null,
"original_id": "GO:0044255",
"relationships": [
{
"predicate": "subClassOf",
"target": "LipidMetabolicProcess"
},
{
"predicate": "subClassOf",
"target": "CellularMetabolicProcess"
}
]
}
| 0 |
{
"document": "cellular lipid metabolic process The chemical reactions and pathways involving lipids, as carried out by individual cells. [{'predicate': 'subClassOf', 'target': 'LipidMetabolicProcess'}, {'predicate': 'subClassOf', 'target': 'CellularMetabolicProcess'}]"
}
|
{
"aliases": null,
"definition": "A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane.",
"id": "CellularLocalization",
"label": "cellular localization",
"logical_definition": null,
"original_id": "GO:0051641",
"relationships": [
{
"predicate": "subClassOf",
"target": "CellularProcess"
},
{
"predicate": "subClassOf",
"target": "Localization"
}
]
}
| 0 |
{
"document": "cellular localization A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane. [{'predicate': 'subClassOf', 'target': 'CellularProcess'}, {'predicate': 'subClassOf', 'target': 'Localization'}]"
}
|
{
"aliases": null,
"definition": "Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.",
"id": "CellularMacromoleculeLocalization",
"label": "cellular macromolecule localization",
"logical_definition": null,
"original_id": "GO:0070727",
"relationships": [
{
"predicate": "subClassOf",
"target": "MacromoleculeLocalization"
},
{
"predicate": "subClassOf",
"target": "CellularLocalization"
}
]
}
| 0 |
{
"document": "cellular macromolecule localization Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell. [{'predicate': 'subClassOf', 'target': 'MacromoleculeLocalization'}, {'predicate': 'subClassOf', 'target': 'CellularLocalization'}]"
}
|
{
"aliases": null,
"definition": "The chemical reactions and pathways by which individual cells transform chemical substances.",
"id": "CellularMetabolicProcess",
"label": "cellular metabolic process",
"logical_definition": null,
"original_id": "GO:0044237",
"relationships": [
{
"predicate": "subClassOf",
"target": "MetabolicProcess"
},
{
"predicate": "subClassOf",
"target": "CellularProcess"
}
]
}
| 0 |
{
"document": "cellular metabolic process The chemical reactions and pathways by which individual cells transform chemical substances. [{'predicate': 'subClassOf', 'target': 'MetabolicProcess'}, {'predicate': 'subClassOf', 'target': 'CellularProcess'}]"
}
|
{
"aliases": null,
"definition": "Metachromasia (also known as metachromacy) is a characteristic color change which certain aniline dyes exhibit when bound to particular substances or when concentrated in solution. For example, the basic dye toluidine blue becomes distinctly pink when bound to cartilage matrix. In the sense used here, the metachromasia refers to a change in color not observed with normal tissues, anomalous staining with the cationic dyes toluidine blue O and Alcian blue resulting from excessive amounts of the polyanionic glycosaminoglycans.",
"id": "CellularMetachromasia",
"label": "Cellular metachromasia",
"logical_definition": null,
"original_id": "HP:0003653",
"relationships": [
{
"predicate": "subClassOf",
"target": "AbnormalityOfMucopolysaccharideMetabolism"
}
]
}
| 0 |
{
"document": "Cellular metachromasia Metachromasia (also known as metachromacy) is a characteristic color change which certain aniline dyes exhibit when bound to particular substances or when concentrated in solution. For example, the basic dye toluidine blue becomes distinctly pink when bound to cartilage matrix. In the sense used here, the metachromasia refers to a change in color not observed with normal tissues, anomalous staining with the cationic dyes toluidine blue O and Alcian blue resulting from excessive amounts of the polyanionic glycosaminoglycans. [{'predicate': 'subClassOf', 'target': 'AbnormalityOfMucopolysaccharideMetabolism'}]"
}
|
{
"aliases": null,
"definition": "The chemical reactions and pathways involving compounds derived from amino acids, organic acids containing one or more amino substituents.",
"id": "CellularModifiedAminoAcidMetabolicProcess",
"label": "cellular modified amino acid metabolic process",
"logical_definition": null,
"original_id": "GO:0006575",
"relationships": [
{
"predicate": "subClassOf",
"target": "CellularMetabolicProcess"
},
{
"predicate": "subClassOf",
"target": "OrganonitrogenCompoundMetabolicProcess"
}
]
}
| 0 |
{
"document": "cellular modified amino acid metabolic process The chemical reactions and pathways involving compounds derived from amino acids, organic acids containing one or more amino substituents. [{'predicate': 'subClassOf', 'target': 'CellularMetabolicProcess'}, {'predicate': 'subClassOf', 'target': 'OrganonitrogenCompoundMetabolicProcess'}]"
}
|
{
"aliases": null,
"definition": "A cellular quality inhering in a cell by virtue of whether the bearer exhibits the ability to move spontaneously.",
"id": "CellularMotility",
"label": "cellular motility",
"logical_definition": null,
"original_id": "PATO:0001488",
"relationships": [
{
"predicate": "subClassOf",
"target": "CellularQuality"
}
]
}
| 0 |
{
"document": "cellular motility A cellular quality inhering in a cell by virtue of whether the bearer exhibits the ability to move spontaneously. [{'predicate': 'subClassOf', 'target': 'CellularQuality'}]"
}
|
{
"aliases": null,
"definition": "The chemical reactions and pathways resulting in the formation of organic and inorganic nitrogenous compounds.",
"id": "CellularNitrogenCompoundBiosyntheticProcess",
"label": "cellular nitrogen compound biosynthetic process",
"logical_definition": null,
"original_id": "GO:0044271",
"relationships": [
{
"predicate": "subClassOf",
"target": "CellularNitrogenCompoundMetabolicProcess"
},
{
"predicate": "subClassOf",
"target": "CellularBiosyntheticProcess"
}
]
}
| 0 |
{
"document": "cellular nitrogen compound biosynthetic process The chemical reactions and pathways resulting in the formation of organic and inorganic nitrogenous compounds. [{'predicate': 'subClassOf', 'target': 'CellularNitrogenCompoundMetabolicProcess'}, {'predicate': 'subClassOf', 'target': 'CellularBiosyntheticProcess'}]"
}
|
{
"aliases": null,
"definition": "The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.",
"id": "CellularNitrogenCompoundMetabolicProcess",
"label": "cellular nitrogen compound metabolic process",
"logical_definition": null,
"original_id": "GO:0034641",
"relationships": [
{
"predicate": "subClassOf",
"target": "NitrogenCompoundMetabolicProcess"
},
{
"predicate": "subClassOf",
"target": "CellularMetabolicProcess"
}
]
}
| 0 |
{
"document": "cellular nitrogen compound metabolic process The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells. [{'predicate': 'subClassOf', 'target': 'NitrogenCompoundMetabolicProcess'}, {'predicate': 'subClassOf', 'target': 'CellularMetabolicProcess'}]"
}
|
{
"aliases": null,
"definition": "A type of non-specific interstitial pneumonia in which interstitial thickening is mainly due to infiltration of inflammatory cells and type II pneumocyte hyperplasia.",
"id": "CellularNonSpecificInterstitialPneumonia",
"label": "Cellular non-specific interstitial pneumonia",
"logical_definition": null,
"original_id": "HP:0033586",
"relationships": [
{
"predicate": "subClassOf",
"target": "NonspecificInterstitialPneumonia"
}
]
}
| 0 |
{
"document": "Cellular non-specific interstitial pneumonia A type of non-specific interstitial pneumonia in which interstitial thickening is mainly due to infiltration of inflammatory cells and type II pneumocyte hyperplasia. [{'predicate': 'subClassOf', 'target': 'NonspecificInterstitialPneumonia'}]"
}
|
{
"aliases": null,
"definition": "A cellular quality that arises by virtue of whether the bearer's disposition to differentiate into one or more mature cell types.",
"id": "CellularPotency",
"label": "cellular potency",
"logical_definition": null,
"original_id": "PATO:0001397",
"relationships": [
{
"predicate": "subClassOf",
"target": "CellularQuality"
}
]
}
| 0 |
{
"document": "cellular potency A cellular quality that arises by virtue of whether the bearer's disposition to differentiate into one or more mature cell types. [{'predicate': 'subClassOf', 'target': 'CellularQuality'}]"
}
|
{
"aliases": null,
"definition": "Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.",
"id": "CellularProcess",
"label": "cellular process",
"logical_definition": null,
"original_id": "GO:0009987",
"relationships": [
{
"predicate": "subClassOf",
"target": "BiologicalProcess"
}
]
}
| 0 |
{
"document": "cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. [{'predicate': 'subClassOf', 'target': 'BiologicalProcess'}]"
}
|
{
"aliases": null,
"definition": "A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular organism.",
"id": "CellularProcessInvolvedInReproductionInMulticellularOrganism",
"label": "cellular process involved in reproduction in multicellular organism",
"logical_definition": null,
"original_id": "GO:0022412",
"relationships": [
{
"predicate": "PartOf",
"target": "MulticellularOrganismReproduction"
},
{
"predicate": "subClassOf",
"target": "CellularProcess"
},
{
"predicate": "subClassOf",
"target": "ReproductiveProcess"
}
]
}
| 0 |
{
"document": "cellular process involved in reproduction in multicellular organism A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular organism. [{'predicate': 'PartOf', 'target': 'MulticellularOrganismReproduction'}, {'predicate': 'subClassOf', 'target': 'CellularProcess'}, {'predicate': 'subClassOf', 'target': 'ReproductiveProcess'}]"
}
|
{
"aliases": null,
"definition": "A monadic quality of continuant that exists at the cellular level of organisation.",
"id": "CellularQuality",
"label": "cellular quality",
"logical_definition": null,
"original_id": "PATO:0001396",
"relationships": [
{
"predicate": "subClassOf",
"target": "AnatomicalStructureQuality"
}
]
}
| 0 |
{
"document": "cellular quality A monadic quality of continuant that exists at the cellular level of organisation. [{'predicate': 'subClassOf', 'target': 'AnatomicalStructureQuality'}]"
}
|
{
"aliases": null,
"definition": "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.",
"id": "CellularResponseToChemicalStimulus",
"label": "cellular response to chemical stimulus",
"logical_definition": null,
"original_id": "GO:0070887",
"relationships": [
{
"predicate": "subClassOf",
"target": "ResponseToChemical"
},
{
"predicate": "subClassOf",
"target": "CellularResponseToStimulus"
}
]
}
| 0 |
{
"document": "cellular response to chemical stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus. [{'predicate': 'subClassOf', 'target': 'ResponseToChemical'}, {'predicate': 'subClassOf', 'target': 'CellularResponseToStimulus'}]"
}
|
{
"aliases": null,
"definition": "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.",
"id": "CellularResponseToCytokineStimulus",
"label": "cellular response to cytokine stimulus",
"logical_definition": null,
"original_id": "GO:0071345",
"relationships": [
{
"predicate": "subClassOf",
"target": "ResponseToCytokine"
},
{
"predicate": "subClassOf",
"target": "CellularResponseToOrganicSubstance"
}
]
}
| 0 |
{
"document": "cellular response to cytokine stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus. [{'predicate': 'subClassOf', 'target': 'ResponseToCytokine'}, {'predicate': 'subClassOf', 'target': 'CellularResponseToOrganicSubstance'}]"
}
|
{
"aliases": null,
"definition": "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.",
"id": "CellularResponseToOrganicSubstance",
"label": "cellular response to organic substance",
"logical_definition": null,
"original_id": "GO:0071310",
"relationships": [
{
"predicate": "subClassOf",
"target": "ResponseToOrganicSubstance"
},
{
"predicate": "subClassOf",
"target": "CellularResponseToChemicalStimulus"
}
]
}
| 0 |
{
"document": "cellular response to organic substance Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus. [{'predicate': 'subClassOf', 'target': 'ResponseToOrganicSubstance'}, {'predicate': 'subClassOf', 'target': 'CellularResponseToChemicalStimulus'}]"
}
|
{
"aliases": null,
"definition": "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell.",
"id": "CellularResponseToStimulus",
"label": "cellular response to stimulus",
"logical_definition": null,
"original_id": "GO:0051716",
"relationships": [
{
"predicate": "subClassOf",
"target": "CellularProcess"
},
{
"predicate": "subClassOf",
"target": "ResponseToStimulus"
}
]
}
| 0 |
{
"document": "cellular response to stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell. [{'predicate': 'subClassOf', 'target': 'CellularProcess'}, {'predicate': 'subClassOf', 'target': 'ResponseToStimulus'}]"
}
|
{
"aliases": null,
"definition": "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).",
"id": "CellularResponseToStress",
"label": "cellular response to stress",
"logical_definition": null,
"original_id": "GO:0033554",
"relationships": [
{
"predicate": "subClassOf",
"target": "ResponseToStress"
},
{
"predicate": "subClassOf",
"target": "CellularResponseToStimulus"
}
]
}
| 0 |
{
"document": "cellular response to stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). [{'predicate': 'subClassOf', 'target': 'ResponseToStress'}, {'predicate': 'subClassOf', 'target': 'CellularResponseToStimulus'}]"
}
|
{
"aliases": null,
"definition": "A type of urinary cast composed of cells incorporated in a protein matrix. The cells can be those found in the urinary sediment (erythrocytes, leuklocytes, renal tubular epithelial cells).",
"id": "CellularUrinaryCasts",
"label": "Cellular urinary casts",
"logical_definition": null,
"original_id": "HP:0031197",
"relationships": [
{
"predicate": "subClassOf",
"target": "Cylindruria"
}
]
}
| 0 |
{
"document": "Cellular urinary casts A type of urinary cast composed of cells incorporated in a protein matrix. The cells can be those found in the urinary sediment (erythrocytes, leuklocytes, renal tubular epithelial cells). [{'predicate': 'subClassOf', 'target': 'Cylindruria'}]"
}
|
{
"aliases": null,
"definition": "An organismal quality inhering in a bearer by virtue of the bearer's consisting cells.",
"id": "Cellularity",
"label": "cellularity",
"logical_definition": null,
"original_id": "PATO:0001992",
"relationships": [
{
"predicate": "subClassOf",
"target": "OrganismalQuality"
}
]
}
| 0 |
{
"document": "cellularity An organismal quality inhering in a bearer by virtue of the bearer's consisting cells. [{'predicate': 'subClassOf', 'target': 'OrganismalQuality'}]"
}
|
{
"aliases": null,
"definition": "A bacterial infection and inflammation of the skin und subcutaneous tissues.",
"id": "Cellulitis",
"label": "Cellulitis",
"logical_definition": null,
"original_id": "HP:0100658",
"relationships": [
{
"predicate": "subClassOf",
"target": "AbnormalityOfConnectiveTissue"
}
]
}
| 0 |
{
"document": "Cellulitis A bacterial infection and inflammation of the skin und subcutaneous tissues. [{'predicate': 'subClassOf', 'target': 'AbnormalityOfConnectiveTissue'}]"
}
|
{
"aliases": null,
"definition": "An odontogenic tumor of the cementum of tooth.",
"id": "Cementoma",
"label": "Cementoma",
"logical_definition": null,
"original_id": "HP:0012328",
"relationships": [
{
"predicate": "subClassOf",
"target": "OdontogenicNeoplasm"
}
]
}
| 0 |
{
"document": "Cementoma An odontogenic tumor of the cementum of tooth. [{'predicate': 'subClassOf', 'target': 'OdontogenicNeoplasm'}]"
}
|
{
"aliases": null,
"definition": "Odontoid tissue that is deposited by cementoblasts onto dentine tissue and functions to attach teeth, odontodes and other odontogenic derivatives to bone tissue and the integument.",
"id": "Cementum",
"label": "cementum",
"logical_definition": null,
"original_id": "UBERON:0001753",
"relationships": [
{
"predicate": "HasDevelopmentalContributionFrom",
"target": "DentalFollicle"
},
{
"predicate": "subClassOf",
"target": "OdontoidTissue"
}
]
}
| 0 |
{
"document": "cementum Odontoid tissue that is deposited by cementoblasts onto dentine tissue and functions to attach teeth, odontodes and other odontogenic derivatives to bone tissue and the integument. [{'predicate': 'HasDevelopmentalContributionFrom', 'target': 'DentalFollicle'}, {'predicate': 'subClassOf', 'target': 'OdontoidTissue'}]"
}
|
{
"aliases": null,
"definition": "The decrease or absence of cementum. The cementum anchors the periodontal ligament attachment fiber between the tooth root and the alveolar bone. Its absence leads to early loss of teeth.",
"id": "CementumHypoplasia",
"label": "Cementum hypoplasia",
"logical_definition": null,
"original_id": "HP:0033787",
"relationships": [
{
"predicate": "subClassOf",
"target": "AbnormalCementumMorphology"
}
]
}
| 0 |
{
"document": "Cementum hypoplasia The decrease or absence of cementum. The cementum anchors the periodontal ligament attachment fiber between the tooth root and the alveolar bone. Its absence leads to early loss of teeth. [{'predicate': 'subClassOf', 'target': 'AbnormalCementumMorphology'}]"
}
|
{
"aliases": null,
"definition": "Excess of cementum on the tooth root surface.",
"id": "CementumOvergrowth",
"label": "Cementum overgrowth",
"logical_definition": null,
"original_id": "HP:0033788",
"relationships": [
{
"predicate": "subClassOf",
"target": "AbnormalCementumMorphology"
}
]
}
| 0 |
{
"document": "Cementum overgrowth Excess of cementum on the tooth root surface. [{'predicate': 'subClassOf', 'target': 'AbnormalCementumMorphology'}]"
}
|
{
"aliases": null,
"definition": "Applies to an abnormality that is located close to the median plane or midline of the body or of the referenced structure.",
"id": "Central",
"label": "Central",
"logical_definition": null,
"original_id": "HP:0030645",
"relationships": [
{
"predicate": "subClassOf",
"target": "SpatialPattern"
}
]
}
| 0 |
{
"document": "Central Applies to an abnormality that is located close to the median plane or midline of the body or of the referenced structure. [{'predicate': 'subClassOf', 'target': 'SpatialPattern'}]"
}
|
{
"aliases": null,
"definition": "A form of adrenal insufficiency related to a lack of ACTH, which leads to a decrease in the production of cortisol by the adrenal glands. Aldosterone production is not usually affected.",
"id": "CentralAdrenalInsufficiency",
"label": "Central adrenal insufficiency",
"logical_definition": null,
"original_id": "HP:0011734",
"relationships": [
{
"predicate": "subClassOf",
"target": "AdrenalInsufficiency"
}
]
}
| 0 |
{
"document": "Central adrenal insufficiency A form of adrenal insufficiency related to a lack of ACTH, which leads to a decrease in the production of cortisol by the adrenal glands. Aldosterone production is not usually affected. [{'predicate': 'subClassOf', 'target': 'AdrenalInsufficiency'}]"
}
|
{
"aliases": null,
"definition": "Apnea resulting from depression of the respiratory centers in the medulla oblongata. There is a lack of respiratory effort rather than obstruction of airflow.",
"id": "CentralApnea",
"label": "Central apnea",
"logical_definition": null,
"original_id": "HP:0002871",
"relationships": [
{
"predicate": "subClassOf",
"target": "Apnea"
}
]
}
| 0 |
{
"document": "Central apnea Apnea resulting from depression of the respiratory centers in the medulla oblongata. There is a lack of respiratory effort rather than obstruction of airflow. [{'predicate': 'subClassOf', 'target': 'Apnea'}]"
}
|
{
"aliases": null,
"definition": "Spinal cord structure that is part of the ventricular system and is filled with cerebral-spinal fluid and runs the length of the spinal cord.",
"id": "CentralCanalOfSpinalCord",
"label": "central canal of spinal cord",
"logical_definition": null,
"original_id": "UBERON:0002291",
"relationships": [
{
"predicate": "PartOf",
"target": "SpinalCord"
},
{
"predicate": "PartOf",
"target": "VentricularSystemOfCentralNervousSystem"
},
{
"predicate": "HasPart",
"target": "CerebrospinalFluid"
},
{
"predicate": "DevelopsFrom",
"target": "NeuralTube"
},
{
"predicate": "ContributesToMorphologyOf",
"target": "SpinalCord"
},
{
"predicate": "ChannelFor",
"target": "CerebrospinalFluid"
},
{
"predicate": "subClassOf",
"target": "AnatomicalConduit"
}
]
}
| 0 |
{
"document": "central canal of spinal cord Spinal cord structure that is part of the ventricular system and is filled with cerebral-spinal fluid and runs the length of the spinal cord. [{'predicate': 'PartOf', 'target': 'SpinalCord'}, {'predicate': 'PartOf', 'target': 'VentricularSystemOfCentralNervousSystem'}, {'predicate': 'HasPart', 'target': 'CerebrospinalFluid'}, {'predicate': 'DevelopsFrom', 'target': 'NeuralTube'}, {'predicate': 'ContributesToMorphologyOf', 'target': 'SpinalCord'}, {'predicate': 'ChannelFor', 'target': 'CerebrospinalFluid'}, {'predicate': 'subClassOf', 'target': 'AnatomicalConduit'}]"
}
|
{
"aliases": null,
"definition": "The presence of disorganized areas called cores in the center of muscle fibers. There is a typical appearance of the biopsy on light microscopy, where the muscle cells have cores that are devoid of mitochondria and specific enzymes. Cores are typically well demarcated and centrally located, but may occasionally be multiple and of eccentric.",
"id": "CentralCoreRegionsInMuscleFibers",
"label": "Central core regions in muscle fibers",
"logical_definition": null,
"original_id": "HP:0030230",
"relationships": [
{
"predicate": "subClassOf",
"target": "AbnormalMuscleFiberMorphology"
}
]
}
| 0 |
{
"document": "Central core regions in muscle fibers The presence of disorganized areas called cores in the center of muscle fibers. There is a typical appearance of the biopsy on light microscopy, where the muscle cells have cores that are devoid of mitochondria and specific enzymes. Cores are typically well demarcated and centrally located, but may occasionally be multiple and of eccentric. [{'predicate': 'subClassOf', 'target': 'AbnormalMuscleFiberMorphology'}]"
}
|
{
"aliases": null,
"definition": null,
"id": "CentralCornealDystrophy",
"label": "Central corneal dystrophy",
"logical_definition": null,
"original_id": "HP:0007881",
"relationships": [
{
"predicate": "subClassOf",
"target": "CentralOpacificationOfTheCornea"
}
]
}
| 0 |
{
"document": "Central corneal dystrophy None [{'predicate': 'subClassOf', 'target': 'CentralOpacificationOfTheCornea'}]"
}
|
{
"aliases": null,
"definition": "Generalized bluish discoloration of the body and the visible mucous membranes, which occurs due to inadequate oxygenation secondary to conditions that lead to an increase in deoxygenated hemoglobin or presence of abnormal hemoglobin.",
"id": "CentralCyanosis",
"label": "Central cyanosis",
"logical_definition": null,
"original_id": "HP:0034032",
"relationships": [
{
"predicate": "subClassOf",
"target": "Cyanosis"
}
]
}
| 0 |
{
"document": "Central cyanosis Generalized bluish discoloration of the body and the visible mucous membranes, which occurs due to inadequate oxygenation secondary to conditions that lead to an increase in deoxygenated hemoglobin or presence of abnormal hemoglobin. [{'predicate': 'subClassOf', 'target': 'Cyanosis'}]"
}
|
{
"aliases": null,
"definition": "A form of diabetes insipidus related to a failure of vasopressin (AVP) release from the hypothalamus.",
"id": "CentralDiabetesInsipidus",
"label": "Central diabetes insipidus",
"logical_definition": null,
"original_id": "HP:0000863",
"relationships": [
{
"predicate": "subClassOf",
"target": "DiabetesInsipidus"
},
{
"predicate": "subClassOf",
"target": "AbnormalityOfThePosteriorPituitary"
}
]
}
| 0 |
{
"document": "Central diabetes insipidus A form of diabetes insipidus related to a failure of vasopressin (AVP) release from the hypothalamus. [{'predicate': 'subClassOf', 'target': 'DiabetesInsipidus'}, {'predicate': 'subClassOf', 'target': 'AbnormalityOfThePosteriorPituitary'}]"
}
|
{
"aliases": null,
"definition": "A congenital diaphragm defect involving the central tendinous (e.g., amuscular) portion of the diaphragm, whereby the entire rim of diaphragmatic musculature is present.",
"id": "CentralDiaphragmaticHernia",
"label": "Central diaphragmatic hernia",
"logical_definition": null,
"original_id": "HP:0025195",
"relationships": [
{
"predicate": "subClassOf",
"target": "CongenitalDiaphragmaticHernia"
}
]
}
| 0 |
{
"document": "Central diaphragmatic hernia A congenital diaphragm defect involving the central tendinous (e.g., amuscular) portion of the diaphragm, whereby the entire rim of diaphragmatic musculature is present. [{'predicate': 'subClassOf', 'target': 'CongenitalDiaphragmaticHernia'}]"
}
|
{
"aliases": null,
"definition": "Microscopic aneurysms of the retinal arterioles near the central part of the fundus, visible as small round dark red dots on the retinal surface (not arising from visible vessels) that are by definition less than the diameter of the major optic veins as they cross the optic disc.",
"id": "CentralFundalArteriolarMicroaneurysms",
"label": "Central fundal arteriolar microaneurysms",
"logical_definition": null,
"original_id": "HP:0008014",
"relationships": [
{
"predicate": "subClassOf",
"target": "RetinalMicroaneurysm"
}
]
}
| 0 |
{
"document": "Central fundal arteriolar microaneurysms Microscopic aneurysms of the retinal arterioles near the central part of the fundus, visible as small round dark red dots on the retinal surface (not arising from visible vessels) that are by definition less than the diameter of the major optic veins as they cross the optic disc. [{'predicate': 'subClassOf', 'target': 'RetinalMicroaneurysm'}]"
}
|
{
"aliases": null,
"definition": "The presence of distinct colors in the central (pupillary) zone of the iris than in the mid-peripheral (ciliary) zone.",
"id": "CentralHeterochromia",
"label": "Central heterochromia",
"logical_definition": null,
"original_id": "HP:0007818",
"relationships": [
{
"predicate": "subClassOf",
"target": "HeterochromiaIridis"
}
]
}
| 0 |
{
"document": "Central heterochromia The presence of distinct colors in the central (pupillary) zone of the iris than in the mid-peripheral (ciliary) zone. [{'predicate': 'subClassOf', 'target': 'HeterochromiaIridis'}]"
}
|
{
"aliases": null,
"definition": "A type of hypothyroidism due to an insufficient stimulation of an otherwise normal thyroid gland. Central hypothyroidism is caused by either pituitary (secondary hypothyroidism) or hypothalamic (tertiary hypothyroidism) defects.",
"id": "CentralHypothyroidism",
"label": "Central hypothyroidism",
"logical_definition": null,
"original_id": "HP:0011787",
"relationships": [
{
"predicate": "subClassOf",
"target": "Hypothyroidism"
}
]
}
| 0 |
{
"document": "Central hypothyroidism A type of hypothyroidism due to an insufficient stimulation of an otherwise normal thyroid gland. Central hypothyroidism is caused by either pituitary (secondary hypothyroidism) or hypothalamic (tertiary hypothyroidism) defects. [{'predicate': 'subClassOf', 'target': 'Hypothyroidism'}]"
}
|
{
"aliases": null,
"definition": null,
"id": "CentralHypoventilation",
"label": "Central hypoventilation",
"logical_definition": null,
"original_id": "HP:0007110",
"relationships": [
{
"predicate": "subClassOf",
"target": "Hypoventilation"
}
]
}
| 0 |
{
"document": "Central hypoventilation None [{'predicate': 'subClassOf', 'target': 'Hypoventilation'}]"
}
|
{
"aliases": null,
"definition": null,
"id": "CentralIncisorTooth",
"label": "central incisor tooth",
"logical_definition": null,
"original_id": "UBERON:0018551",
"relationships": null
}
| 0 |
{
"document": "central incisor tooth None None"
}
|
{
"aliases": null,
"definition": "CD4-positive, alpha-beta memory T cell with the phenotype CCR7-positive, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative.",
"id": "CentralMemoryCD4Positive_alphaBetaTCell",
"label": "central memory CD4-positive, alpha-beta T cell",
"logical_definition": null,
"original_id": "CL:0000904",
"relationships": [
{
"predicate": "subClassOf",
"target": "CD4Positive_alphaBetaMemoryTCell_CD45ROPositive"
}
]
}
| 0 |
{
"document": "central memory CD4-positive, alpha-beta T cell CD4-positive, alpha-beta memory T cell with the phenotype CCR7-positive, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative. [{'predicate': 'subClassOf', 'target': 'CD4Positive_alphaBetaMemoryTCell_CD45ROPositive'}]"
}
|
{
"aliases": null,
"definition": "CD8-positive, alpha-beta memory T cell with the phenotype CCR7-positive, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative.",
"id": "CentralMemoryCD8Positive_alphaBetaTCell",
"label": "central memory CD8-positive, alpha-beta T cell",
"logical_definition": null,
"original_id": "CL:0000907",
"relationships": [
{
"predicate": "subClassOf",
"target": "CD8Positive_alphaBetaMemoryTCell_CD45ROPositive"
}
]
}
| 0 |
{
"document": "central memory CD8-positive, alpha-beta T cell CD8-positive, alpha-beta memory T cell with the phenotype CCR7-positive, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative. [{'predicate': 'subClassOf', 'target': 'CD8Positive_alphaBetaMemoryTCell_CD45ROPositive'}]"
}
|
{
"aliases": null,
"definition": "The presence of a depressed line (\"canal\") in the center of the nail.",
"id": "CentralNailCanal",
"label": "Central nail canal",
"logical_definition": null,
"original_id": "HP:0030818",
"relationships": [
{
"predicate": "subClassOf",
"target": "NailDystrophy"
}
]
}
| 0 |
{
"document": "Central nail canal The presence of a depressed line (\"canal\") in the center of the nail. [{'predicate': 'subClassOf', 'target': 'NailDystrophy'}]"
}
|
{
"aliases": null,
"definition": "The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord.",
"id": "CentralNervousSystem",
"label": "central nervous system",
"logical_definition": null,
"original_id": "UBERON:0001017",
"relationships": [
{
"predicate": "PartOf",
"target": "NervousSystem"
},
{
"predicate": "ImmediateTransformationOf",
"target": "FutureCentralNervousSystem"
},
{
"predicate": "subClassOf",
"target": "OrganSystemSubdivision"
}
]
}
| 0 |
{
"document": "central nervous system The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord. [{'predicate': 'PartOf', 'target': 'NervousSystem'}, {'predicate': 'ImmediateTransformationOf', 'target': 'FutureCentralNervousSystem'}, {'predicate': 'subClassOf', 'target': 'OrganSystemSubdivision'}]"
}
|
{
"aliases": null,
"definition": "Axonal spheroids are bubble-like biological features that form on most degenerating axons. During neurodegeneration, bubble-like swellings form along the length of the axon, a primary and early effect of dynamic axonal deformation. These varicosities, spheroids, or swellings have been described as beads on a string and branches bearing fruit, and they frequently appear on degenerating axons. The focal swellings on degenerating axons, axonal spheroids, are often filled with cellular debris such as organelles, pathological proteins, and disorganized cytoskeletal elements.",
"id": "CentralNervousSystemAxonalSpheroid",
"label": "Central nervous system axonal spheroid",
"logical_definition": null,
"original_id": "HP:0034381",
"relationships": [
{
"predicate": "subClassOf",
"target": "MorphologicalCentralNervousSystemAbnormality"
}
]
}
| 0 |
{
"document": "Central nervous system axonal spheroid Axonal spheroids are bubble-like biological features that form on most degenerating axons. During neurodegeneration, bubble-like swellings form along the length of the axon, a primary and early effect of dynamic axonal deformation. These varicosities, spheroids, or swellings have been described as beads on a string and branches bearing fruit, and they frequently appear on degenerating axons. The focal swellings on degenerating axons, axonal spheroids, are often filled with cellular debris such as organelles, pathological proteins, and disorganized cytoskeletal elements. [{'predicate': 'subClassOf', 'target': 'MorphologicalCentralNervousSystemAbnormality'}]"
}
|
{
"aliases": null,
"definition": "A multi cell part structure that is part of a central nervous system.",
"id": "CentralNervousSystemCellPartCluster",
"label": "central nervous system cell part cluster",
"logical_definition": null,
"original_id": "UBERON:0011215",
"relationships": null
}
| 0 |
{
"document": "central nervous system cell part cluster A multi cell part structure that is part of a central nervous system. None"
}
|
{
"aliases": null,
"definition": "A fluid-filled sac (cyst) located within the central nervous system.",
"id": "CentralNervousSystemCyst",
"label": "Central nervous system cyst",
"logical_definition": null,
"original_id": "HP:0030724",
"relationships": [
{
"predicate": "subClassOf",
"target": "MorphologicalCentralNervousSystemAbnormality"
}
]
}
| 0 |
{
"document": "Central nervous system cyst A fluid-filled sac (cyst) located within the central nervous system. [{'predicate': 'subClassOf', 'target': 'MorphologicalCentralNervousSystemAbnormality'}]"
}
|
{
"aliases": null,
"definition": null,
"id": "CentralNervousSystemDegeneration",
"label": "Central nervous system degeneration",
"logical_definition": null,
"original_id": "HP:0007009",
"relationships": [
{
"predicate": "subClassOf",
"target": "AtrophyDegenerationAffectingTheCentralNervousSystem"
}
]
}
| 0 |
{
"document": "Central nervous system degeneration None [{'predicate': 'subClassOf', 'target': 'AtrophyDegenerationAffectingTheCentralNervousSystem'}]"
}
|
{
"aliases": null,
"definition": "A loosely defined group of drugs that tend to reduce the activity of the central nervous system.",
"id": "CentralNervousSystemDepressant",
"label": "central nervous system depressant",
"logical_definition": null,
"original_id": "CHEBI:35488",
"relationships": [
{
"predicate": "subClassOf",
"target": "CentralNervousSystemDrug"
}
]
}
| 0 |
{
"document": "central nervous system depressant A loosely defined group of drugs that tend to reduce the activity of the central nervous system. [{'predicate': 'subClassOf', 'target': 'CentralNervousSystemDrug'}]"
}
|
{
"aliases": null,
"definition": "The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.",
"id": "CentralNervousSystemDevelopment",
"label": "central nervous system development",
"logical_definition": null,
"original_id": "GO:0007417",
"relationships": [
{
"predicate": "PartOf",
"target": "NervousSystemDevelopment"
},
{
"predicate": "subClassOf",
"target": "SystemDevelopment"
}
]
}
| 0 |
{
"document": "central nervous system development The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. [{'predicate': 'PartOf', 'target': 'NervousSystemDevelopment'}, {'predicate': 'subClassOf', 'target': 'SystemDevelopment'}]"
}
|
{
"aliases": null,
"definition": "A class of drugs producing both physiological and psychological effects through a variety of mechanisms involving the central nervous system.",
"id": "CentralNervousSystemDrug",
"label": "central nervous system drug",
"logical_definition": null,
"original_id": "CHEBI:35470",
"relationships": [
{
"predicate": "subClassOf",
"target": "Drug"
}
]
}
| 0 |
{
"document": "central nervous system drug A class of drugs producing both physiological and psychological effects through a variety of mechanisms involving the central nervous system. [{'predicate': 'subClassOf', 'target': 'Drug'}]"
}
|
{
"aliases": null,
"definition": "A layer of of the central nervous system that is part of gray matter.",
"id": "CentralNervousSystemGrayMatterLayer",
"label": "central nervous system gray matter layer",
"logical_definition": null,
"original_id": "UBERON:0016548",
"relationships": null
}
| 0 |
{
"document": "central nervous system gray matter layer A layer of of the central nervous system that is part of gray matter. None"
}
|
{
"aliases": null,
"definition": "A tissue-resident macrophage found in the central nervous system.",
"id": "CentralNervousSystemMacrophage",
"label": "central nervous system macrophage",
"logical_definition": null,
"original_id": "CL:0000878",
"relationships": [
{
"predicate": "subClassOf",
"target": "TissueResidentMacrophage"
}
]
}
| 0 |
{
"document": "central nervous system macrophage A tissue-resident macrophage found in the central nervous system. [{'predicate': 'subClassOf', 'target': 'TissueResidentMacrophage'}]"
}
|
{
"aliases": null,
"definition": "The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by an oligodendrocyte in the central nervous system.",
"id": "CentralNervousSystemMyelinFormation",
"label": "central nervous system myelin formation",
"logical_definition": null,
"original_id": "GO:0032289",
"relationships": [
{
"predicate": "PartOf",
"target": "CentralNervousSystemMyelination"
},
{
"predicate": "subClassOf",
"target": "MyelinAssembly"
}
]
}
| 0 |
{
"document": "central nervous system myelin formation The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by an oligodendrocyte in the central nervous system. [{'predicate': 'PartOf', 'target': 'CentralNervousSystemMyelination'}, {'predicate': 'subClassOf', 'target': 'MyelinAssembly'}]"
}
|
{
"aliases": null,
"definition": "The process in which the structure and material content of mature central nervous system myelin is kept in a functional state.",
"id": "CentralNervousSystemMyelinMaintenance",
"label": "central nervous system myelin maintenance",
"logical_definition": null,
"original_id": "GO:0032286",
"relationships": [
{
"predicate": "PartOf",
"target": "CentralNervousSystemMyelination"
},
{
"predicate": "subClassOf",
"target": "MyelinMaintenance"
}
]
}
| 0 |
{
"document": "central nervous system myelin maintenance The process in which the structure and material content of mature central nervous system myelin is kept in a functional state. [{'predicate': 'PartOf', 'target': 'CentralNervousSystemMyelination'}, {'predicate': 'subClassOf', 'target': 'MyelinMaintenance'}]"
}
|
{
"aliases": null,
"definition": "The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of oligodendrocytes in the central nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.",
"id": "CentralNervousSystemMyelination",
"label": "central nervous system myelination",
"logical_definition": null,
"original_id": "GO:0022010",
"relationships": [
{
"predicate": "PartOf",
"target": "OligodendrocyteDevelopment"
},
{
"predicate": "subClassOf",
"target": "AxonEnsheathmentInCentralNervousSystem"
},
{
"predicate": "subClassOf",
"target": "Myelination"
}
]
}
| 0 |
{
"document": "central nervous system myelination The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of oligodendrocytes in the central nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier. [{'predicate': 'PartOf', 'target': 'OligodendrocyteDevelopment'}, {'predicate': 'subClassOf', 'target': 'AxonEnsheathmentInCentralNervousSystem'}, {'predicate': 'subClassOf', 'target': 'Myelination'}]"
}
|
{
"aliases": null,
"definition": "Any neuron that is part of a central nervous system.",
"id": "CentralNervousSystemNeuron",
"label": "central nervous system neuron",
"logical_definition": null,
"original_id": "CL:2000029",
"relationships": null
}
| 0 |
{
"document": "central nervous system neuron Any neuron that is part of a central nervous system. None"
}
|
{
"aliases": null,
"definition": "A pericyte of the central nervous system.",
"id": "CentralNervousSystemPericyte",
"label": "central nervous system pericyte",
"logical_definition": null,
"original_id": "CL:0002575",
"relationships": [
{
"predicate": "subClassOf",
"target": "Pericyte"
}
]
}
| 0 |
{
"document": "central nervous system pericyte A pericyte of the central nervous system. [{'predicate': 'subClassOf', 'target': 'Pericyte'}]"
}
|
{
"aliases": null,
"definition": "A layer of of the central nervous system that is composed of white matter.",
"id": "CentralNervousSystemWhiteMatterLayer",
"label": "central nervous system white matter layer",
"logical_definition": null,
"original_id": "UBERON:0016549",
"relationships": null
}
| 0 |
{
"document": "central nervous system white matter layer A layer of of the central nervous system that is composed of white matter. None"
}
|
{
"aliases": null,
"definition": "Reduced transparency of the central portion of the corneal stroma.",
"id": "CentralOpacificationOfTheCornea",
"label": "Central opacification of the cornea",
"logical_definition": null,
"original_id": "HP:0011493",
"relationships": [
{
"predicate": "subClassOf",
"target": "OpacificationOfTheCornealStroma"
}
]
}
| 0 |
{
"document": "Central opacification of the cornea Reduced transparency of the central portion of the corneal stroma. [{'predicate': 'subClassOf', 'target': 'OpacificationOfTheCornealStroma'}]"
}
|
{
"aliases": null,
"definition": null,
"id": "CentralPartOfBodyOfBonyVertebralCentrum",
"label": "central part of body of bony vertebral centrum",
"logical_definition": null,
"original_id": "UBERON:0016412",
"relationships": [
{
"predicate": "PartOf",
"target": "BonyVertebralCentrum"
},
{
"predicate": "subClassOf",
"target": "ZoneOfBoneOrgan"
}
]
}
| 0 |
{
"document": "central part of body of bony vertebral centrum None [{'predicate': 'PartOf', 'target': 'BonyVertebralCentrum'}, {'predicate': 'subClassOf', 'target': 'ZoneOfBoneOrgan'}]"
}
|
{
"aliases": null,
"definition": "Reduced transparency of the central posterior portion of the corneal stroma.",
"id": "CentralPosteriorCornealOpacity",
"label": "Central posterior corneal opacity",
"logical_definition": null,
"original_id": "HP:0008511",
"relationships": [
{
"predicate": "subClassOf",
"target": "CentralOpacificationOfTheCornea"
}
]
}
| 0 |
{
"document": "Central posterior corneal opacity Reduced transparency of the central posterior portion of the corneal stroma. [{'predicate': 'subClassOf', 'target': 'CentralOpacificationOfTheCornea'}]"
}
|
{
"aliases": null,
"definition": "A primitive neuroectodermal neoplasm that occurs in the central nervous system.",
"id": "CentralPrimitiveNeuroectodermalTumor",
"label": "Central primitive neuroectodermal tumor",
"logical_definition": null,
"original_id": "HP:0030070",
"relationships": [
{
"predicate": "subClassOf",
"target": "PrimitiveNeuroectodermalTumor"
}
]
}
| 0 |
{
"document": "Central primitive neuroectodermal tumor A primitive neuroectodermal neoplasm that occurs in the central nervous system. [{'predicate': 'subClassOf', 'target': 'PrimitiveNeuroectodermalTumor'}]"
}
|
{
"aliases": null,
"definition": "The central retinal artery (retinal artery) branches off the ophthalmic artery, running inferior to the optic nerve within its dural sheath to the eyeball. [WP,unvetted].",
"id": "CentralRetinalArtery",
"label": "central retinal artery",
"logical_definition": null,
"original_id": "UBERON:0001620",
"relationships": [
{
"predicate": "PartOf",
"target": "VasculatureOfRetina"
},
{
"predicate": "Supplies",
"target": "Retina"
},
{
"predicate": "DevelopsFromPartOf",
"target": "HyaloidArtery"
},
{
"predicate": "BranchingPartOf",
"target": "OphthalmicArtery"
},
{
"predicate": "subClassOf",
"target": "Artery"
}
]
}
| 0 |
{
"document": "central retinal artery The central retinal artery (retinal artery) branches off the ophthalmic artery, running inferior to the optic nerve within its dural sheath to the eyeball. [WP,unvetted]. [{'predicate': 'PartOf', 'target': 'VasculatureOfRetina'}, {'predicate': 'Supplies', 'target': 'Retina'}, {'predicate': 'DevelopsFromPartOf', 'target': 'HyaloidArtery'}, {'predicate': 'BranchingPartOf', 'target': 'OphthalmicArtery'}, {'predicate': 'subClassOf', 'target': 'Artery'}]"
}
|
{
"aliases": null,
"definition": "Blockage of the main artery in the retina. The typical presentation is one of profound monocular visual loss.",
"id": "CentralRetinalArteryOcclusion",
"label": "Central retinal artery occlusion",
"logical_definition": null,
"original_id": "HP:0025342",
"relationships": [
{
"predicate": "subClassOf",
"target": "RetinalArterialOcclusion"
},
{
"predicate": "subClassOf",
"target": "AbnormalityOfCentralRetinalArtery"
}
]
}
| 0 |
{
"document": "Central retinal artery occlusion Blockage of the main artery in the retina. The typical presentation is one of profound monocular visual loss. [{'predicate': 'subClassOf', 'target': 'RetinalArterialOcclusion'}, {'predicate': 'subClassOf', 'target': 'AbnormalityOfCentralRetinalArtery'}]"
}
|
{
"aliases": null,
"definition": null,
"id": "CentralRetinalExudate",
"label": "Central retinal exudate",
"logical_definition": null,
"original_id": "HP:0007822",
"relationships": [
{
"predicate": "subClassOf",
"target": "RetinalExudate"
}
]
}
| 0 |
{
"document": "Central retinal exudate None [{'predicate': 'subClassOf', 'target': 'RetinalExudate'}]"
}
|
{
"aliases": null,
"definition": "Central retinal vein occlusion is an occlusion of the main retinal vein posterior to the lamina cribrosa of the optic nerve and is typically caused by thrombosis.",
"id": "CentralRetinalVeinOcclusion",
"label": "Central retinal vein occlusion",
"logical_definition": null,
"original_id": "HP:0020166",
"relationships": [
{
"predicate": "subClassOf",
"target": "RetinalVeinOcclusion"
}
]
}
| 0 |
{
"document": "Central retinal vein occlusion Central retinal vein occlusion is an occlusion of the main retinal vein posterior to the lamina cribrosa of the optic nerve and is typically caused by thrombosis. [{'predicate': 'subClassOf', 'target': 'RetinalVeinOcclusion'}]"
}
|
{
"aliases": null,
"definition": "The presence of an increased number of twists and turns of retinal blood vessels (arteries, arterioles, veins, venules).",
"id": "CentralRetinalVesselVascularTortuosity",
"label": "Central retinal vessel vascular tortuosity",
"logical_definition": null,
"original_id": "HP:0007768",
"relationships": [
{
"predicate": "subClassOf",
"target": "RetinalArterialTortuosity"
}
]
}
| 0 |
{
"document": "Central retinal vessel vascular tortuosity The presence of an increased number of twists and turns of retinal blood vessels (arteries, arterioles, veins, venules). [{'predicate': 'subClassOf', 'target': 'RetinalArterialTortuosity'}]"
}
|
{
"aliases": null,
"definition": "An area of depressed vision located at the point of fixation and that interferes with central vision.",
"id": "CentralScotoma",
"label": "Central scotoma",
"logical_definition": null,
"original_id": "HP:0000603",
"relationships": [
{
"predicate": "subClassOf",
"target": "Scotoma"
}
]
}
| 0 |
{
"document": "Central scotoma An area of depressed vision located at the point of fixation and that interferes with central vision. [{'predicate': 'subClassOf', 'target': 'Scotoma'}]"
}
|
{
"aliases": null,
"definition": "An anomaly of the retina with serous detachment of the neurosensory retina secondary to one or more focal lesions of the retinal pigment epithelium (RPE), and associated with blurred vision, usually in one eye only and perceived typically by the patient as a dark spot in the centre of the visual field with associated micropsia and metamorphopsia. Normal vision often recurs spontaneously within a few months.",
"id": "CentralSerousChorioretinopathy",
"label": "Central serous chorioretinopathy",
"logical_definition": null,
"original_id": "HP:0025567",
"relationships": [
{
"predicate": "subClassOf",
"target": "AbnormalChorioretinalMorphology"
}
]
}
| 0 |
{
"document": "Central serous chorioretinopathy An anomaly of the retina with serous detachment of the neurosensory retina secondary to one or more focal lesions of the retinal pigment epithelium (RPE), and associated with blurred vision, usually in one eye only and perceived typically by the patient as a dark spot in the centre of the visual field with associated micropsia and metamorphopsia. Normal vision often recurs spontaneously within a few months. [{'predicate': 'subClassOf', 'target': 'AbnormalChorioretinalMorphology'}]"
}
|
{
"aliases": null,
"definition": "Sleep apnea resulting from a transient abolition of the central drive to the ventilatory muscles.",
"id": "CentralSleepApnea",
"label": "Central sleep apnea",
"logical_definition": null,
"original_id": "HP:0010536",
"relationships": [
{
"predicate": "subClassOf",
"target": "SleepApnea"
}
]
}
| 0 |
{
"document": "Central sleep apnea Sleep apnea resulting from a transient abolition of the central drive to the ventilatory muscles. [{'predicate': 'subClassOf', 'target': 'SleepApnea'}]"
}
|
{
"aliases": null,
"definition": "The central sulcus is a fold in the cerebral cortex of brains in vertebrates. Also called the central fissure, it was originally called the fissure of Rolando or the Rolandic fissure, after Luigi Rolando. The central sulcus is a prominent landmark of the brain, separating the parietal lobe from the frontal lobe and the primary motor cortex from the primary somatosensory cortex. [WP,unvetted].",
"id": "CentralSulcus",
"label": "central sulcus",
"logical_definition": null,
"original_id": "UBERON:0002916",
"relationships": [
{
"predicate": "PartOf",
"target": "CerebralCortex"
}
]
}
| 0 |
{
"document": "central sulcus The central sulcus is a fold in the cerebral cortex of brains in vertebrates. Also called the central fissure, it was originally called the fissure of Rolando or the Rolandic fissure, after Luigi Rolando. The central sulcus is a prominent landmark of the brain, separating the parietal lobe from the frontal lobe and the primary motor cortex from the primary somatosensory cortex. [WP,unvetted]. [{'predicate': 'PartOf', 'target': 'CerebralCortex'}]"
}
|
{
"aliases": null,
"definition": "Vein that is central to a lobule in the liver.",
"id": "CentralVeinOfLiver",
"label": "central vein of liver",
"logical_definition": null,
"original_id": "UBERON:0006841",
"relationships": [
{
"predicate": "PartOf",
"target": "LiverLobule"
},
{
"predicate": "subClassOf",
"target": "Vein"
}
]
}
| 0 |
{
"document": "central vein of liver Vein that is central to a lobule in the liver. [{'predicate': 'PartOf', 'target': 'LiverLobule'}, {'predicate': 'subClassOf', 'target': 'Vein'}]"
}
|
{
"aliases": null,
"definition": null,
"id": "CentralVertebralHypoplasia",
"label": "Central vertebral hypoplasia",
"logical_definition": null,
"original_id": "HP:0008463",
"relationships": [
{
"predicate": "subClassOf",
"target": "VertebralHypoplasia"
}
]
}
| 0 |
{
"document": "Central vertebral hypoplasia None [{'predicate': 'subClassOf', 'target': 'VertebralHypoplasia'}]"
}
|
{
"aliases": null,
"definition": "A central Y-shaped metacarpal is the result of a partial fusion of two central metacarpals (i.e., metacarpals 2-4) of the hand, with the two arms of the Y pointing in the distal direction. Central Y-shaped metacarpals may be seen as a result of a central polydactyly with partial fusion of the duplicated metacarpal.",
"id": "CentralYShapedMetacarpal",
"label": "Central Y-shaped metacarpal",
"logical_definition": null,
"original_id": "HP:0006145",
"relationships": [
{
"predicate": "subClassOf",
"target": "YShapedMetacarpals"
}
]
}
| 0 |
{
"document": "Central Y-shaped metacarpal A central Y-shaped metacarpal is the result of a partial fusion of two central metacarpals (i.e., metacarpals 2-4) of the hand, with the two arms of the Y pointing in the distal direction. Central Y-shaped metacarpals may be seen as a result of a central polydactyly with partial fusion of the duplicated metacarpal. [{'predicate': 'subClassOf', 'target': 'YShapedMetacarpals'}]"
}
|
{
"aliases": null,
"definition": "Endochondral bone located between the proximal and distal rows of carpals or tarsals and thus representing the central carpals or tarsals[PHENOSCAPE].",
"id": "Centrale",
"label": "centrale",
"logical_definition": null,
"original_id": "UBERON:0012131",
"relationships": [
{
"predicate": "DevelopsFrom",
"target": "CentraleCartilage"
}
]
}
| 0 |
{
"document": "centrale Endochondral bone located between the proximal and distal rows of carpals or tarsals and thus representing the central carpals or tarsals[PHENOSCAPE]. [{'predicate': 'DevelopsFrom', 'target': 'CentraleCartilage'}]"
}
|
{
"aliases": null,
"definition": "A centrale endochondral element that is composed primarily of cartilage tissue.",
"id": "CentraleCartilage",
"label": "centrale cartilage",
"logical_definition": null,
"original_id": "UBERON:0015077",
"relationships": null
}
| 0 |
{
"document": "centrale cartilage A centrale endochondral element that is composed primarily of cartilage tissue. None"
}
|
{
"aliases": null,
"definition": "Endochondral element located between the proximal and distal rows of carpals or tarsals and thus representing the central carpals or tarsals[PHENOSCAPE].",
"id": "CentraleEndochondralElement",
"label": "centrale endochondral element",
"logical_definition": null,
"original_id": "UBERON:0015067",
"relationships": [
{
"predicate": "PartOf",
"target": "MesopodialSkeleton"
},
{
"predicate": "subClassOf",
"target": "EndochondralElement"
}
]
}
| 0 |
{
"document": "centrale endochondral element Endochondral element located between the proximal and distal rows of carpals or tarsals and thus representing the central carpals or tarsals[PHENOSCAPE]. [{'predicate': 'PartOf', 'target': 'MesopodialSkeleton'}, {'predicate': 'subClassOf', 'target': 'EndochondralElement'}]"
}
|
{
"aliases": null,
"definition": "An abnormality in which the nuclei of sarcomeres take on an abnormally central localization (or in which this feature is found in an increased proportion of muscle cells).",
"id": "CentrallyNucleatedSkeletalMuscleFibers",
"label": "Centrally nucleated skeletal muscle fibers",
"logical_definition": null,
"original_id": "HP:0003687",
"relationships": [
{
"predicate": "subClassOf",
"target": "AbnormalMuscleFiberMorphology"
}
]
}
| 0 |
{
"document": "Centrally nucleated skeletal muscle fibers An abnormality in which the nuclei of sarcomeres take on an abnormally central localization (or in which this feature is found in an increased proportion of muscle cells). [{'predicate': 'subClassOf', 'target': 'AbnormalMuscleFiberMorphology'}]"
}
|
{
"aliases": null,
"definition": "Located in the center of the secondary pulmonary lobules, which are the functional units of the lungs.",
"id": "Centrilobular",
"label": "Centrilobular",
"logical_definition": null,
"original_id": "HP:0033816",
"relationships": [
{
"predicate": "subClassOf",
"target": "SpatialPattern"
}
]
}
| 0 |
{
"document": "Centrilobular Located in the center of the secondary pulmonary lobules, which are the functional units of the lungs. [{'predicate': 'subClassOf', 'target': 'SpatialPattern'}]"
}
|
{
"aliases": null,
"definition": "A type of emphysema characterized by destroyed centrilobular alveolar walls and enlargement of respiratory bronchioles and associated alveoli. This is the commonest form of emphysema in cigarette smokers. CT findings are centrilobular areas of decreased attenuation, usually without visible walls, of nonuniform distribution and predominantly located in upper lung zones.",
"id": "CentrilobularEmphysema",
"label": "Centrilobular emphysema",
"logical_definition": null,
"original_id": "HP:0032966",
"relationships": [
{
"predicate": "subClassOf",
"target": "Emphysema"
}
]
}
| 0 |
{
"document": "Centrilobular emphysema A type of emphysema characterized by destroyed centrilobular alveolar walls and enlargement of respiratory bronchioles and associated alveoli. This is the commonest form of emphysema in cigarette smokers. CT findings are centrilobular areas of decreased attenuation, usually without visible walls, of nonuniform distribution and predominantly located in upper lung zones. [{'predicate': 'subClassOf', 'target': 'Emphysema'}]"
}
|
{
"aliases": null,
"definition": "A hazy area of increased attenuation in centrilobular areas of the lung with preserved bronchial and vascular markings seen on a computer tomography scan. Centrilobular refers to a location that is central within secondary pulmonary lobules.",
"id": "CentrilobularGroundGlassOpacificationOnPulmonaryHRCT",
"label": "Centrilobular ground-glass opacification on pulmonary HRCT",
"logical_definition": null,
"original_id": "HP:0025180",
"relationships": [
{
"predicate": "subClassOf",
"target": "GroundGlassOpacification"
}
]
}
| 0 |
{
"document": "Centrilobular ground-glass opacification on pulmonary HRCT A hazy area of increased attenuation in centrilobular areas of the lung with preserved bronchial and vascular markings seen on a computer tomography scan. Centrilobular refers to a location that is central within secondary pulmonary lobules. [{'predicate': 'subClassOf', 'target': 'GroundGlassOpacification'}]"
}
|
{
"aliases": null,
"definition": "A scotoma (area of diminished vision within the visual field) located between the central point of fixation and the blind spot with a roughly horizontal oval shape.",
"id": "CentrocecalScotoma",
"label": "Centrocecal scotoma",
"logical_definition": null,
"original_id": "HP:0000576",
"relationships": [
{
"predicate": "subClassOf",
"target": "Scotoma"
}
]
}
| 0 |
{
"document": "Centrocecal scotoma A scotoma (area of diminished vision within the visual field) located between the central point of fixation and the blind spot with a roughly horizontal oval shape. [{'predicate': 'subClassOf', 'target': 'Scotoma'}]"
}
|
{
"aliases": null,
"definition": "A tarsal bone that is formed from the fusion of the central and 4th tarsal bones.",
"id": "CentroquartalBone",
"label": "centroquartal bone",
"logical_definition": null,
"original_id": "UBERON:0012288",
"relationships": null
}
| 0 |
{
"document": "centroquartal bone A tarsal bone that is formed from the fusion of the central and 4th tarsal bones. None"
}
|
{
"aliases": null,
"definition": "A congenital defect in the skull, whereby there is a protrusion of part of the cranial contents through a congenital defect in the cranium, usually covered with skin or mucous membrane. The term encephalocele refers to a subclass of these lesions in which brain tissue protrudes through the defect.",
"id": "Cephalocele",
"label": "Cephalocele",
"logical_definition": null,
"original_id": "HP:0011815",
"relationships": [
{
"predicate": "subClassOf",
"target": "AbnormalSkullMorphology"
}
]
}
| 0 |
{
"document": "Cephalocele A congenital defect in the skull, whereby there is a protrusion of part of the cranial contents through a congenital defect in the cranium, usually covered with skin or mucous membrane. The term encephalocele refers to a subclass of these lesions in which brain tissue protrudes through the defect. [{'predicate': 'subClassOf', 'target': 'AbnormalSkullMorphology'}]"
}
|
{
"aliases": null,
"definition": "Hemorrhage between the skull and periosteum of a newborn resulting from rupture of blood vessels that cross the periosteum.",
"id": "Cephalohematoma",
"label": "Cephalohematoma",
"logical_definition": null,
"original_id": "HP:0012541",
"relationships": [
{
"predicate": "subClassOf",
"target": "AbnormalDelivery"
},
{
"predicate": "subClassOf",
"target": "AbnormalBleeding"
}
]
}
| 0 |
{
"document": "Cephalohematoma Hemorrhage between the skull and periosteum of a newborn resulting from rupture of blood vessels that cross the periosteum. [{'predicate': 'subClassOf', 'target': 'AbnormalDelivery'}, {'predicate': 'subClassOf', 'target': 'AbnormalBleeding'}]"
}
|
{
"aliases": null,
"definition": "Ceramides (N-acyl-sphingoid bases) are a major subclass of sphingoid base derivatives with an amide-linked fatty acid. The fatty acids are typically saturated or monounsaturated with chain lengths from 14 to 26 carbon atoms; the presence of a hydroxyl group on carbon 2 is fairly common. Ceramides are generally precursors of more complex sphingolipids. In the illustrated generalised structure, R(1) = OH, OX (where X = acyl, glycosyl, phosphate, phosphonate, etc.), or H.",
"id": "Ceramide",
"label": "ceramide",
"logical_definition": null,
"original_id": "CHEBI:17761",
"relationships": [
{
"predicate": "subClassOf",
"target": "Sphingolipid"
},
{
"predicate": "subClassOf",
"target": "Carboxamide"
}
]
}
| 0 |
{
"document": "ceramide Ceramides (N-acyl-sphingoid bases) are a major subclass of sphingoid base derivatives with an amide-linked fatty acid. The fatty acids are typically saturated or monounsaturated with chain lengths from 14 to 26 carbon atoms; the presence of a hydroxyl group on carbon 2 is fairly common. Ceramides are generally precursors of more complex sphingolipids. In the illustrated generalised structure, R(1) = OH, OX (where X = acyl, glycosyl, phosphate, phosphonate, etc.), or H. [{'predicate': 'subClassOf', 'target': 'Sphingolipid'}, {'predicate': 'subClassOf', 'target': 'Carboxamide'}]"
}
|
{
"aliases": null,
"definition": "The chemical reactions and pathways involving ceramides, any N-acylated sphingoid.",
"id": "CeramideMetabolicProcess",
"label": "ceramide metabolic process",
"logical_definition": null,
"original_id": "GO:0006672",
"relationships": [
{
"predicate": "subClassOf",
"target": "SphingolipidMetabolicProcess"
},
{
"predicate": "subClassOf",
"target": "AmideMetabolicProcess"
}
]
}
| 0 |
{
"document": "ceramide metabolic process The chemical reactions and pathways involving ceramides, any N-acylated sphingoid. [{'predicate': 'subClassOf', 'target': 'SphingolipidMetabolicProcess'}, {'predicate': 'subClassOf', 'target': 'AmideMetabolicProcess'}]"
}
|
{
"aliases": null,
"definition": "Cerebellar agenesis is defined by the near complete absence of cerebellar tissue with only remnants of the anterior vermis, flocculus, and/or middle cerebellar peduncles.",
"id": "CerebellarAgenesis",
"label": "Cerebellar agenesis",
"logical_definition": null,
"original_id": "HP:0012642",
"relationships": [
{
"predicate": "subClassOf",
"target": "AplasiaHypoplasiaOfTheCerebellum"
}
]
}
| 0 |
{
"document": "Cerebellar agenesis Cerebellar agenesis is defined by the near complete absence of cerebellar tissue with only remnants of the anterior vermis, flocculus, and/or middle cerebellar peduncles. [{'predicate': 'subClassOf', 'target': 'AplasiaHypoplasiaOfTheCerebellum'}]"
}
|
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