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Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.
Only one report links phenylpropanolamine consumption to an intracerebral hemorrhage in a patient with an AVM.
Cerebral haemorrhage
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Pseudoephedrine-induced hemorrhage associated with a cerebral vascular malformation.
Congenital cerebrovascular anomaly
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Since 1979, over 30 published case reports have documented the relationship between phenylpropanolamine and stroke.
Cerebrovascular accident
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This is a case of pseudoephedrine-induced intracerebral hemorrhage in a patient with an underlying vascular malformation.
Cerebral haemorrhage
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Rapid onset of quetiapine-induced diabetic ketoacidosis in an elderly patient: a case report.
Diabetic ketoacidosis
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We report a case of reversible DKA and new-onset DM that developed in a demented patient who was treated with quetiapine for 14 days.
Diabetic ketoacidosis
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Pulmonary leukostasis secondary to all-trans retinoic acid in the treatment of acute promyelocytic leukemia in first relapse.
Leukostasis syndrome
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Eruptive epidermoid cysts resulting from treatment with imiquimod.
Dermoid cyst
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METHODS: A 79-year-old woman being treated with imiquimod 5 days per week for a nodular basal cell developed a verrucous plaque over the treatment area after 7 weeks of therapy.
Skin papilloma
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The multiple comedones and ruptured epidermoid cysts are newly reported adverse effects of imiquimod therapy.
Acne
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We report an unusual case of massive fluoxetine ingestion resulting in neurological and cardiovascular toxicity resulting in death.
Death
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Hepatocellular damage following therapeutic intravenous iron sucrose infusion in a child.
Hepatocellular injury
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The case reported here is of a child given a large dose of intravenous iron sucrose (16 mg/kg) over 3 hours, who subsequently developed features of systemic iron toxicity.
Systemic toxicity
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Five personal observations of an acute amnestic episode in younger individuals after intake of clioquinol are described together with three observations from the medical literature.
Amnesia
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The clinical aspect closely resembled classical transient global amnesia but the episode after clioquinol lasted longer (24 hours to three days) and a more or less extensive retrograde amnesia persisted permanently.
Retrograde Amnesia
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Transient global amnesia after clioquinol: five personal observations from outside Japan.
Transient global Amnesia
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In the other patient, a 78-year-old woman, Neisseria mucosa knee arthritis occurred after a single sodium hyaluronate injection.
Arthritis
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One patient was an 80-year-old woman who was admitted for Staphylococcus aureus knee arthritis after several intraarticular injections of sodium hyaluronate and corticosteroids.
Arthritis bacterial
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Septic knee arthritis after intra-articular hyaluronate injection.
Arthritis bacterial
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Acute dystonia induced by lamivudine.
Dystonia
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ADR induced by drug treatment can be a side effect of treatment with antipsychotic drugs and other drugs; however, there have been no reports of lamivudine-induced ADR in the English literature.
Dystonia
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The authors report two cases of acute dystonic reactions (ADRs) as a side effect of lamivudine.
Dystonia
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The authors think that although lamivudine is widely used and well tolerated, it can cause ADRs, which are reversible after drug withdrawal.
Dystonia
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Pleuropulmonary fibrosis after long-term treatment with the dopamine agonist pergolide for Parkinson Disease.
Pulmonary fibrosis
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OBJECTIVE: To our knowledge, this is the first published case report of an adolescent girl with a mitochondrial disorder and depression who displayed both new-onset psychotic and increased mood symptoms during treatment with risperidone.
Affective disorder
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Risperidone-induced psychosis and depression in a child with a mitochondrial disorder.
Depression
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Fatal radiation myelopathy after high-dose busulfan and melphalan chemotherapy and radiotherapy for Ewing's sarcoma: a review of the literature and implications for practice.
Radiation myelopathy
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Gemcitabine-induced pericardial effusion and tamponade after unblocked cardiac irradiation.
Pericardial Effusion
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Gemcitabine therapy has been associated with radiation recall reactions when used in the treatment of carcinoma.
Recall phenomenon
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Physicians should be aware of the potential for developing a gemcitabine-induced radiation recall reaction resulting in hemodynamically significant pericardial effusion.
Pericardial Effusion
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We report four cases of hemodynamically significant pericardial effusion in patients with refractory lymphoma who were receiving gemcitabine, all of whom had a history of mediastinal radiation without subcarinal blocking.
Pericardial Effusion
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A patient with generalized MG was effectively managed with MM but developed CNS lymphoma after 3 years of treatment.
Central nervous system lymphoma
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Primary CNS lymphoma complicating treatment of myasthenia gravis with mycophenolate mofetil.
Central nervous system lymphoma
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Primary CNS lymphoma regressed on withdrawal of MM.
Central nervous system lymphoma
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Baclofen withdrawal: a cause of prolonged fever in the intensive care unit.
Pyrexia
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Baclofen withdrawal syndrome resulting from underdosing of oral baclofen should be considered as a potential source of prolonged fever in the intensive care unit.
Withdrawal syndrome
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The patient continued to have fever and autonomic instability without evidence of infection which entirely resolved within 24 hours of reinstitution of full preadmission dosing of oral baclofen.
Autonomic nervous system imbalance
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We report a case of baclofen withdrawal syndrome resulting from oral baclofen underdosing.
Withdrawal syndrome
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After discontinuing captopril and starting systemic steroids, her symptomatology rapidly improved, and her eosinophilia and radiographic abnormalities both resolved.
Eosinophilia
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Captopril-induced pulmonary infiltrates with eosinophilia in an infant with congenital heart disease.
Eosinophilic pneumonia
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We report a case of an infant with complex congenital heart disease who was placed on captopril for afterload reduction following cardiac surgery and subsequently developed pulmonary infiltrates with eosinophilia.
Eosinophilic pneumonia
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Can propofol precipitate pancreatitis in patients with Cushing's syndrome?
Pancreatitis
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Since elevated cortisol levels in Cushing's disease poses a threat for pancreatitis, there is a possibility that patients with Cushing's disease might be more prone to acute pancreatitis following propofol administration.
Pancreatitis acute
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Since recent studies have reported no negative interactions with concurrent use, we here report three cases (one case of a prolonged seizure, a serotonin syndrome and a focal seizure) of severe lithium-induced side effects while patients underwent ECT without complications and lithium serum levels were still subtherapeutic.
Partial seizures
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CD20-negative T-cell-rich B-cell lymphoma as a progression of a nodular lymphocyte-predominant Hodgkin's lymphoma treated with rituximab: a molecular analysis using laser capture microdissection.
B-cell lymphoma
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Recently, CD20-negative tumors have been described after Rituximab therapy.
B-cell lymphoma
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A 51-year old physically fit woman experienced angio-oedema and hypotensive shock after irbesartan ingestion requiring noradrenaline infusion.
angio-OOedema
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To our knowledge, our report is one of the first on shock and angio-oedema from irbesartan.
angio-OOedema
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She died within six weeks of developing congestive heart failure coupled with liver failure due to haemosiderosis despite regular use of desferrioxamine.
Cardiac failure congestive
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Transfusion haemosiderosis inspite of regular use of desferrioxamine: case report.
Haemochromatosis
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One of the side-effects of intravitreal triamcinolone is the development of cataract, and it is known that cataract extraction can exacerbate macular degeneration.
Cataract
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Severe loss of vision after removal of cataract caused by intravitreal triamcinolone in combination with photodynamic therapy for exudative age-related macular degeneration.
Cataract
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Rhabdomyolysis caused by tocolysis with oral ritodrine hydrochloride in a pregnant patient with myotonic dystrophy.
Rhabdomyolysis
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Rhabdomyolysis has been recognized as a complication of tocolytic therapy with ritodrine hydrochloride.
Rhabdomyolysis
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We report here a rare case of ritodrine-hydrochloride-induced rhabdomyolysis in a pregnant patient with myotonic dystrophy.
Rhabdomyolysis
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Acute myocardial ischemia following accidental intravenous administration of epinephrine in high concentration.
Myocardial ischaemia
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We present a case of acute epinephrine toxicity resulting in acute myocardial ischemia in a young boy with combined variable immunodeficiency syndrome who developed severe allergic reaction to intravenous immunoglobulin, and was subsequently given epinephrine by mistake intravenously rather than subcutaneously.
Myocardial ischaemia
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Polysomnographic and pharmacokinetic findings in levodopa-induced augmentation of restless legs syndrome.
Restless legs syndrome
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Videopolysomnographic and pharmacokinetic studies with monitoring of plasma levodopa levels demonstrated marked motor hyperactivity during augmentation, with anarchic discharges of motor unit potentials, tonic grouped discharges and flexor spasms, associated with painful dysesthesia.
Muscle contractions involuntary
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The major side effect of infliximab is infection.
Infection
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This report describes a probable case of infliximab-induced membranous nephropathy.
Glomerulonephritis membranous
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Linezolid-induced dyserythropoiesis: chloramphenicol toxicity revisited.
Anaemia
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We report here two cases of dyserythropoietic anaemia associated with long-term linezolid use that share striking similarities to chloramphenicol-associated myelotoxicity.
Anaemia
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A selective association between fluoxetine and extensive, prominent eye movements in nonrapid eye movement (NREM) sleep was detected, utilizing Fisher's exact one-tailed statistic (p less than 0.00001 for each comparison).
Sleep disorder
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In addition, a 31-year-old man with obsessive-compulsive disorder developed RBD soon after starting fluoxetine therapy, which persisted at PSG study 19 months after fluoxetine discontinuation.
Sleep disorder
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Prominent eye movements during NREM sleep and REM sleep behavior disorder associated with fluoxetine treatment of depression and obsessive-compulsive disorder.
Sleep disorder
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Because of serious side effects of an increase in the QT interval causing torsades de pointes, dofetilide must be initiated with close monitoring of the QT interval in an inpatient setting.
Torsade de pointes
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Marked QT prolongation and torsades de pointes secondary to acute ischemia in an elderly man taking dofetilide for atrial fibrillation: a cautionary tale.
Myocardial ischaemia
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We report marked QT prolongation and torsades de pointes in a setting of flash pulmonary edema resulting from acute myocardial ischemia in a patient who was being treated with dofetilide for atrial fibrillation.
Myocardial ischaemia
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Prominent positive U waves appearing with high-dose intravenous phenylephrine.
Electrocardiogram abnormal
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While on a maximal dose of phenylephrine she developed prominent positive U waves, which disappeared with the cessation of the drug.
Electrocardiogram abnormal
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Hepatoxicity is a rare complication of SRL therapy and may be connected with some diagnostic and/or therapeutic problems.
Hepatotoxicity
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Sirolimus-associated hepatotoxicity in the kidney graft recipient.
Hepatotoxicity
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The aim of our paper was to describe hepatotoxicity of sirolimus (SRL) in a kidney graft recipient.
Hepatotoxicity
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CASE REPORT: We present a case of a 28-yr-old male who developed a severe case of nephrotic syndrome while being treated for relapsing/remitting Multiple Sclerosis (RRMS) with weekly injections of interferon beta 1a.
Nephrotic syndrome
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Nephrotic syndrome in a multiple sclerosis patient treated with interferon beta 1a.
Nephrotic syndrome
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SUBSEQUENT COURSE: The nephrosis resolved almost completely once the interferon was stopped and after immunosuppressive treatment.
Nephrotic syndrome
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This latest (third) report suggests that the safety profile should be reexamined and at least raises the question of potential renal toxicity of interferons in MS.
Nephropathy toxic
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Capecitabine-induced multifocal leukoencephalopathy: a report of five cases.
Progressive multifocal leukoencephalopathy
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The authors report five additional cases of capecitabine-induced multifocal leukoencephalopathy.
Progressive multifocal leukoencephalopathy
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A 56-year-old white woman with a diagnosis of reactive depression developed severe UI after a 30 days' treatment with venlafaxine 75 mg/day.
Urinary Incontinence
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The authors report a case of urinary incontinence (UI) that occurred in a woman after administration of venlafaxine.
Urinary Incontinence
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Venlafaxine-induced urinary incontinence resolved after switching to sertraline.
Urinary Incontinence
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Diagnosis of hypothyroidism during treatment can be difficult because of the common side effects of alpha interferon.
Hypothyroidism
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Sustained hypothyroidism induced by recombinant alpha interferon in patients with chronic hepatitis C.
Hypothyroidism
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Thyroid dysfunction has been reported in patients with malignant disease treated with recombinant alpha interferon.
Thyroid disorder
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Two cases of hypothyroidism in patients with chronic hepatitis C treated with recombinant alpha interferon are reported.
Hypothyroidism
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Atrial fibrillation after vardenafil therapy.
Atrial fibrillation
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We report a case admitted with a first-detected, symptomatic paroxysmal atrial fibrillation in a healthy patient after self-medication with vardenafil.
Atrial fibrillation
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We describe a case of infection with Mycobacterium abscessus in a 67-year-old woman receiving infliximab as a component of her therapy for RA.
Mycobacterium abscessus infection
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DIAGNOSIS: Interferon alpha-2b-induced cardiomyopathy.
Cardiomyopathy
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Reversible cardiomyopathy caused by administration of interferon alpha.
Cardiomyopathy
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In this case senna was likely the cause of a subacute cholestatic hepatitis exemplifying again the potential role of herbal related liver injury.
Liver injury
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Subacute cholestatic hepatitis likely related to the use of senna for chronic constipation.
Hepatitis cholestatic
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We report a case of senna-induced cholestatic hepatitis which was not diagnosed at presentation.
Hepatitis cholestatic
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Based on the history and clinical features, a diagnosis of insulin-induced lipohypertrophy was made.
Lipohypertrophy
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Insulin-induced lipohypertrophy: report of a case with histopathology.
Lipohypertrophy
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Thus, the possible in vivo effects of insulin on adipocytes were clearly observed in this case of insulin-induced lipohypertrophy.
Lipohypertrophy
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To our knowledge, this is the first report of insulin-induced lipohypertrophy with detailed histological examinations.
Lipohypertrophy
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A 7-year-old girl developed diabetes mellitus and exocrine pancreatic insufficiency after 3.5 years of almost continuous treatment with azathioprine and/or prednisone for idiopathic auto-immune haemolytic anaemia.
Diabetes mellitus