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What is one of the most frequent dis-orders that causes secondary hypertension?
Primary aldosteronism
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the most frequent dis-orders that causes secondary hypertension?. ### Response: Primary aldosteronism.
What percentage of patients with hypertension have primary aldosteronism?
5% to 10%
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients with hypertension have primary aldosteronism?. ### Response: 5% to 10%.
What causes secondary hypertension?
Primary aldosteronism
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What causes secondary hypertension?. ### Response: Primary aldosteronism.
What causes greater target organ damage in primary aldosteronism than in primary hypertony?
hypertension
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What causes greater target organ damage in primary aldosteronism than in primary hypertony?. ### Response: hypertension.
How much increase in HF do patients with primary aldenosterononism have in their blood pressure?
3.7-fold
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much increase in HF do patients with primary aldenosterononism have in their blood pressure?. ### Response: 3.7-fold.
What is AF?
atrial fibrillation
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is AF?. ### Response: atrial fibrillation.
What are LVH and diastolic dysfunc-tion?
increased left ventricular hypertrophy
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are LVH and diastolic dysfunc-tion?. ### Response: increased left ventricular hypertrophy.
Why do patients with primary hypertension have more kidney damage?
matched for BP level
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why do patients with primary hypertension have more kidney damage?. ### Response: matched for BP level.
What is the primary hypertension matched for?
BP level
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the primary hypertension matched for?. ### Response: BP level.
What are the deleterious effects of aldosterone overproduction often reversible with?
unilateral laparoscopic adrenalectomy
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the deleterious effects of aldosterone overproduction often reversible with?. ### Response: unilateral laparoscopic adrenalectomy.
Who should be screening patients with hypertension at increased risk of?
primary aldosteron-ism
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who should be screening patients with hypertension at increased risk of?. ### Response: primary aldosteron-ism.
What is the term for an adrenal lesion discovered on a computed tomography or MRI scan?
incidentaloma
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the term for an adrenal lesion discovered on a computed tomography or MRI scan?. ### Response: incidentaloma.
What type of aldosteron-ism is beneficial?
primary
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of aldosteron-ism is beneficial?. ### Response: primary.
Patients with hypertension and a history of early onset hypertension may have what?
primary aldosteronism
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with hypertension and a history of early onset hypertension may have what?. ### Response: primary aldosteronism.
What may cause primary aldosteronism?
glucocorticoid-remediable al-dosteronism
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may cause primary aldosteronism?. ### Response: glucocorticoid-remediable al-dosteronism.
What is the most accurate and reliable means of screening for primary Table 14?
aldosterone:renin activity ratio
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the most accurate and reliable means of screening for primary Table 14?. ### Response: aldosterone:renin activity ratio.
What is a common cause of elevated BP*?
offee use in patients with hypertension
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a common cause of elevated BP*?. ### Response: offee use in patients with hypertension.
How many drinks a day should you drink alcohol for women?
≀1
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many drinks a day should you drink alcohol for women?. ### Response: ≀1.
What is another name for amphetamine?
mphetamines
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What is another name for SSRIs?
alternative agents
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What type of antipsychotics are clozapine?
Atypical
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of antipsychotics are clozapine?. ### Response: Atypical.
Where is behavior therapy recommended?
ADHDS
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is behavior therapy recommended?. ### Response: ADHDS.
Aripiprazole and ziprasidone are examples of what type of agents?
mineralocorticoid receptor antagonists
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Aripiprazole and ziprasidone are examples of what type of agents?. ### Response: mineralocorticoid receptor antagonists.
How much caffeine should a person consume in a day?
<300 mg/d
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much caffeine should a person consume in a day?. ### Response: <300 mg/d.
What type of hypertension is caffeine associated with?
uncontrolled
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of hypertension is caffeine associated with?. ### Response: uncontrolled.
How is caffeine used in patients with hypertension?
acute increases in BP
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is caffeine used in patients with hypertension?. ### Response: acute increases in BP.
How many primary outcome events were there in the benazepril/amlodipine group?
552
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many primary outcome events were there in the benazepril/amlodipine group?. ### Response: 552.
What was the mean follow-up of the trial?
36 months
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the mean follow-up of the trial?. ### Response: 36 months.
How long did it take for the trial to be terminated?
36 months
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did it take for the trial to be terminated?. ### Response: 36 months.
What was the absolute risk reduction of the benazepril/hydrochlorothiazide group?
2.2%
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the absolute risk reduction of the benazepril/hydrochlorothiazide group?. ### Response: 2.2%.
How many participants were in the ACCOMPLISH trial with diabetes mellitus?
73 913
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many participants were in the ACCOMPLISH trial with diabetes mellitus?. ### Response: 73 913.
How many recent meta-analyses investigated the effect of BP lowering in patients with type 2 diabetes mellitus?
Two
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many recent meta-analyses investigated the effect of BP lowering in patients with type 2 diabetes mellitus?. ### Response: Two.
How many patients were included in the first meta-analysis?
37 760
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were included in the first meta-analysis?. ### Response: 37 760.
How long was the follow-up of intensive BP control?
1 year
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long was the follow-up of intensive BP control?. ### Response: 1 year.
What was associated with a 10% reduction in all-cause mortality and a 17% reduction in stroke?
Intensive BP control
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was associated with a 10% reduction in all-cause mortality and a 17% reduction in stroke?. ### Response: Intensive BP control.
How much increase was there in serious adverse effects?
20%
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much increase was there in serious adverse effects?. ### Response: 20%.
What percentage increase in serious adverse effects was there?
20%
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage increase in serious adverse effects was there?. ### Response: 20%.
What was the SBP of a stroke at 120 mm Hg?
<120 mm Hg
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the SBP of a stroke at 120 mm Hg?. ### Response: <120 mm Hg.
At what level was there a 40% increase in severe adverse events?
<130 mm Hg
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: At what level was there a 40% increase in severe adverse events?. ### Response: <130 mm Hg.
How many patients with diabetes mellitus were randomized in the second meta-analysis?
73 913
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with diabetes mellitus were randomized in the second meta-analysis?. ### Response: 73 913.
How many patient-years of exposure were there in 31 intervention trials?
295 652
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patient-years of exposure were there in 31 intervention trials?. ### Response: 295 652.
What did more aggressive treatment reduce stroke incidence by?
9%
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did more aggressive treatment reduce stroke incidence by?. ### Response: 9%.
How much did less aggressive BP control reduce the risk of stroke?
31%
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much did less aggressive BP control reduce the risk of stroke?. ### Response: 31%.
What was the RR of BP?
0.61
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the RR of BP?. ### Response: 0.61.
In a meta-regression analy-sis, what was the risk for stroke reduced by?
13%
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In a meta-regression analy-sis, what was the risk for stroke reduced by?. ### Response: 13%.
What percentage for each 2-mm Hg reduction in DBP?
11.5%
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage for each 2-mm Hg reduction in DBP?. ### Response: 11.5%.
What did the Medical Research Council/British Heart Foundation Heart Protection Study find in patients with diabetes mellitus?
BP lowering
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Medical Research Council/British Heart Foundation Heart Protection Study find in patients with diabetes mellitus?. ### Response: BP lowering.
What study found a 24% reduction in the rate of major CVD events?
Medical Research Council/British Heart Foundation Heart Protection Study
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What study found a 24% reduction in the rate of major CVD events?. ### Response: Medical Research Council/British Heart Foundation Heart Protection Study.
What did the addition of a statin to existing treatments in high-risk patients result in?
24% reduction (95% CI, 19–28) in the rate of major CVD events
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the addition of a statin to existing treatments in high-risk patients result in?. ### Response: 24% reduction (95% CI, 19–28) in the rate of major CVD events.
A 22% reduction in major vascular events regardless of the presence of what?
known coronary heart disease or cholesterol levels
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A 22% reduction in major vascular events regardless of the presence of what?. ### Response: known coronary heart disease or cholesterol levels.
What did the Collaborative Atorvastatin Diabetes Study report?
the primary outcome results were similar
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Collaborative Atorvastatin Diabetes Study report?. ### Response: the primary outcome results were similar.
How much reduction in strokes were found among 5963 diabetic individu-als treated with statin in addition to best medical care?
24%
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much reduction in strokes were found among 5963 diabetic individu-als treated with statin in addition to best medical care?. ### Response: 24%.
What is the acronym for the Collaborative Atorvastatin Diabetes Study?
CARDS
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for the Collaborative Atorvastatin Diabetes Study?. ### Response: CARDS.
What did the CARDS report in patients with type 2 diabetes mellitus with at least 1 additional risk factor?
an LDL cholesterol level <160 mg/dL
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the CARDS report in patients with type 2 diabetes mellitus with at least 1 additional risk factor?. ### Response: an LDL cholesterol level <160 mg/dL.
How much reduction did treatment with a statin result in?
48%
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much reduction did treatment with a statin result in?. ### Response: 48%.
How much reduction in stroke did statin treatment result in?
48%
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much reduction in stroke did statin treatment result in?. ### Response: 48%.
What was the 95% CI for stroke?
0.83–0.98
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the 95% CI for stroke?. ### Response: 0.83–0.98.
What drug is used to treat multifocal atrial tachycardia?
amiodarone
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What drug is used to treat multifocal atrial tachycardia?. ### Response: amiodarone.
What is the name of the drug used in the treatment of multifacial atrial heart failure?
amiodarone
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug used in the treatment of multifacial atrial heart failure?. ### Response: amiodarone.
How many patients were treated with verapamil in 1987?
231
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were treated with verapamil in 1987?. ### Response: 231.
What is the effective treatment of multifocal atrial tachycardia with amiodarone?
231
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effective treatment of multifocal atrial tachycardia with amiodarone?. ### Response: 231.
When did Jpn Heart J. 1989;30:301-12?
1989
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Jpn Heart J. 1989;30:301-12?. ### Response: 1989.
What is the name of the drug that is used for treatment of multifacial atrial heart disease?
amiodarone
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug that is used for treatment of multifacial atrial heart disease?. ### Response: amiodarone.
Where can verapamil be obtained?
http://ahajournals.org
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can verapamil be obtained?. ### Response: http://ahajournals.org.
What is the name of the journal that was published in 1987?
South Med J
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that was published in 1987?. ### Response: South Med J.
When was this article first published?
April 23, 2023
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this article first published?. ### Response: April 23, 2023.
What may cause hyperkalemia or a reversible decline in kidney function in patients with low eGFR?
ACEi, ARB, and direct renin inhibitor(DRI) therapy in patients with CKD, with or without diabetes
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may cause hyperkalemia or a reversible decline in kidney function in patients with low eGFR?. ### Response: ACEi, ARB, and direct renin inhibitor(DRI) therapy in patients with CKD, with or without diabetes.
What is the role of dual therapy with RASi?
We recommend avoiding any combination of ACEi, ARB, and direct renin inhibitor(DRI) therapy in patients with CKD
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the role of dual therapy with RASi?. ### Response: We recommend avoiding any combination of ACEi, ARB, and direct renin inhibitor(DRI) therapy in patients with CKD.
What type of diabetes does 1B have?
CKD, with or without diabetes
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of diabetes does 1B have?. ### Response: CKD, with or without diabetes.
What is the name of the organization that recommends a diabetic diet?
kidney-international
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the organization that recommends a diabetic diet?. ### Response: kidney-international.
What is a relationship considered to be if it is less than significant under the preceding definition?
modest
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a relationship considered to be if it is less than significant under the preceding definition?. ### Response: modest.
Relationships that exist with no financial benefit are also included for the purpose of what?
transparency
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Relationships that exist with no financial benefit are also included for the purpose of what?. ### Response: transparency.
Names are listed in alphabetical order within each table.
review
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Names are listed in alphabetical order within each table.. ### Response: review.
What is the acronym for American Association for Thoracic Surgery?
AATS
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for American Association for Thoracic Surgery?. ### Response: AATS.
What does ACC stand for?
American College of Cardiology
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ACC stand for?. ### Response: American College of Cardiology.
How are names listed in each category of review?
in alphabetical order
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How are names listed in each category of review?. ### Response: in alphabetical order.
What is the acronym for American College of Cardiology?
ACC
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for American College of Cardiology?. ### Response: ACC.
What is AHA?
American Heart Association
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is AHA?. ### Response: American Heart Association.
AIG stands for Assembly of International Governors.
AIG
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: AIG stands for Assembly of International Governors.. ### Response: AIG.
ASE stands for American Society of Echocardiography.
ASE
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: ASE stands for American Society of Echocardiography.. ### Response: ASE.
HRS stands for Heart Rhythm Society.
HRS, Heart Rhythm Society
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: HRS stands for Heart Rhythm Society.. ### Response: HRS, Heart Rhythm Society.
MAUDE stands for what?
McGill Adult Unit for Congenital Heart Disease Excellence
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: MAUDE stands for what?. ### Response: McGill Adult Unit for Congenital Heart Disease Excellence.
What is the acronym for Adult Unit for Congenital Heart Disease Excellence?
MAUDE
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for Adult Unit for Congenital Heart Disease Excellence?. ### Response: MAUDE.
What is SCAI?
Society for Cardiovascular Angiography and Interventions
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is SCAI?. ### Response: Society for Cardiovascular Angiography and Interventions.
Where is STS located?
Society of Thoracic Surgeons
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is STS located?. ### Response: Society of Thoracic Surgeons.
When was the appendix downloaded?
April 28, 2023
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the appendix downloaded?. ### Response: April 28, 2023.
What is the therapeutic range of heparin for coronary indica-tions?
unknown
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the therapeutic range of heparin for coronary indica-tions?. ### Response: unknown.
What is more research needed to identify the optimal approach for monitoring?
unfractionated heparin (UFH) therapy
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is more research needed to identify the optimal approach for monitoring?. ### Response: unfractionated heparin (UFH) therapy.
What is the range of heparin for coronary indica-tions?
unknown
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the range of heparin for coronary indica-tions?. ### Response: unknown.
What is likely to correspond to 10% lower than those used for treatment of patients with VTE?
heparin
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is likely to correspond to 10% lower than those used for treatment of patients with VTE?. ### Response: heparin.
The results of a ran-domized trial in patients with what disease showed that unmonitored weight-adjusted subcutaneous hepatic was given twice daily?
VTE
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The results of a ran-domized trial in patients with what disease showed that unmonitored weight-adjusted subcutaneous hepatic was given twice daily?. ### Response: VTE.
What is a term used to describe heparin resistance?
Heparin Resistance
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a term used to describe heparin resistance?. ### Response: Heparin Resistance.
What did the study show was as safe and effic-tive as unmonitored, weight-adjusted LMWH?
subcutaneous heparin
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the study show was as safe and effic-tive as unmonitored, weight-adjusted LMWH?. ### Response: subcutaneous heparin.
What is a term used to describe the situation where patients require unusually high doses of heparin to achieve a therapeutic aPTT?
VTE
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a term used to describe the situation where patients require unusually high doses of heparin to achieve a therapeutic aPTT?. ### Response: VTE.
What may cause drug-induced heparin resis-tance?
Aprotinin and nitroglycerin
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may cause drug-induced heparin resis-tance?. ### Response: Aprotinin and nitroglycerin.
How many elevations in the levels of heparain-binding proteins?
38,87
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many elevations in the levels of heparain-binding proteins?. ### Response: 38,87.
Aprotinin and nitroglycerin may cause what?
heparin resis-tance
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Aprotinin and nitroglycerin may cause what?. ### Response: heparin resis-tance.
What is the association with nitroglycerin controversial?
drug-induced heparin resis-tance
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the association with nitroglycerin controversial?. ### Response: drug-induced heparin resis-tance.
What was the target range for anti-Xa levels?
between 0.35-0.7 units/mL
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the target range for anti-Xa levels?. ### Response: between 0.35-0.7 units/mL.
What did randomized patients receive?
lower doses of heparin
Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did randomized patients receive?. ### Response: lower doses of heparin.