prognosis/cardio-docs-qa · Datasets at Hugging Face

What is the glomerular filtration rate?

<30 mL·min−1·1.73 m−2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the glomerular filtration rate?. ### Response: <30 mL·min−1·1.73 m−2.

What can be substituted if a -blocker is contraindicated?

non-DHP CCB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be substituted if a -blocker is contraindicated?. ### Response: non-DHP CCB.

What is a non-DHP CCB substituted for if left ventricular dysfunction or HF is present?

β-blocker

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a non-DHP CCB substituted for if left ventricular dysfunction or HF is present?. ### Response: β-blocker.

HF, diabetes mellitus, or left ventricular dysfunction are symptoms of what?

heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: HF, diabetes mellitus, or left ventricular dysfunction are symptoms of what?. ### Response: heart failure.

What is the name of the drug that is used to treat HF?

Loop diuretic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug that is used to treat HF?. ### Response: Loop diuretic.

What is the acronym for abdominal aortic aneurysm?

AAAIIb/BAAA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for abdominal aortic aneurysm?. ### Response: AAAIIb/BAAA.

What does ACS stand for?

acute coronary syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ACS stand for?. ### Response: acute coronary syndrome.

Where can ahajournals.org be accessed?

http://ahajournals.org

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can ahajournals.org be accessed?. ### Response: http://ahajournals.org.

Why do blockers occur?

rapid absorption or low bioavail-ability due to high first-pass metabolism by the cytochromeP450 (ie, CYP3A4 ) system

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why do blockers occur?. ### Response: rapid absorption or low bioavail-ability due to high first-pass metabolism by the cytochromeP450 (ie, CYP3A4 ) system.

What is the cytochrome P450 system responsible for?

high first-pass metabolism

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cytochrome P450 system responsible for?. ### Response: high first-pass metabolism.

Do blockers result in high intraindividual and interindividual variability?

These pharmacokinetic propertiesresult in high intraindividual and interindividual variability

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Do blockers result in high intraindividual and interindividual variability?. ### Response: These pharmacokinetic propertiesresult in high intraindividual and interindividual variability.

What is cyclosporine?

carbamaz-epine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is cyclosporine?. ### Response: carbamaz-epine.

What is carbamaz-epine?

cyclosporine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is carbamaz-epine?. ### Response: cyclosporine.

How much increase in digoxin concentrations in first week of therapy?

50% to70%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much increase in digoxin concentrations in first week of therapy?. ### Response: 50% to70%.

Why should verapamil and diltiazem be avoided?

because of potentially pro-found adverse effects on AV nodal conduction, heart rate, orcardiac contractility

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why should verapamil and diltiazem be avoided?. ### Response: because of potentially pro-found adverse effects on AV nodal conduction, heart rate, orcardiac contractility.

What is the most well tolerated calcium channel blocker?

diltiazem

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the most well tolerated calcium channel blocker?. ### Response: diltiazem.

What are the major adverse effects of dihydropyridines related to?

vasodilation and systemic hypotension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the major adverse effects of dihydropyridines related to?. ### Response: vasodilation and systemic hypotension.

What can verapamil cause?

constipation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can verapamil cause?. ### Response: constipation.

What is effective in the treatment ofall forms of angina?

Nitrates

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is effective in the treatment ofall forms of angina?. ### Response: Nitrates.

How do nitrates relax vascular smooth muscle in the systemic arteries?

Nitrates

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How do nitrates relax vascular smooth muscle in the systemic arteries?. ### Response: Nitrates.

What does short-term continuous nitroglycerin delivery protect the endothelium from?

experimental ischemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does short-term continuous nitroglycerin delivery protect the endothelium from?. ### Response: experimental ischemia.

What reduces ischemia during coronary angioplasty and physical exercise in IHD patients?

Short-term continuous nitroglycerin delivery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What reduces ischemia during coronary angioplasty and physical exercise in IHD patients?. ### Response: Short-term continuous nitroglycerin delivery.

What causes dilation of the artery wall not affected by plaque but independent of an intact endothelium?

Nitroglycerin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What causes dilation of the artery wall not affected by plaque but independent of an intact endothelium?. ### Response: Nitroglycerin.

Nitroglycerin contributes to coronary blood flowredistribution by augmenting collateral flow and lowering ventricular diastolic pressure?

866

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Nitroglycerin contributes to coronary blood flowredistribution by augmenting collateral flow and lowering ventricular diastolic pressure?. ### Response: 866.

What is flowredistribution?

coronary blood

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is flowredistribution?. ### Response: coronary blood.

What is increased by augmenting collateral flow and lowering ventricular diastolic pressure?

coronary blood flow

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is increased by augmenting collateral flow and lowering ventricular diastolic pressure?. ### Response: coronary blood flow.

Preload is reduced, leading to what?

reduc-tions in myocardial wall tension and myocardial oxygendemand

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Preload is reduced, leading to what?. ### Response: reduc-tions in myocardial wall tension and myocardial oxygendemand.

What does nitroglycerin have antithrombotic and antiplatelet effects?

868,869

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does nitroglycerin have antithrombotic and antiplatelet effects?. ### Response: 868,869.

What could offset the short-term ischemic preconditioning effects of nitrate therapy?

Oxygen free radicalrelease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could offset the short-term ischemic preconditioning effects of nitrate therapy?. ### Response: Oxygen free radicalrelease.

How is long-term nitrogen therapy associated with endothelialdysfunction?

via accumulation of the same oxygen free radi-cals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is long-term nitrogen therapy associated with endothelialdysfunction?. ### Response: via accumulation of the same oxygen free radi-cals.

The oxygen free radical accumulation increases what?

arterial sensitivity to vasoconstrictors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The oxygen free radical accumulation increases what?. ### Response: arterial sensitivity to vasoconstrictors.

What is beneficial in short-term administra-tion?

oxygen free radi-cals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is beneficial in short-term administra-tion?. ### Response: oxygen free radi-cals.

What increases arterial sensitivity to vasoconstrictors such as angiotensin II?

oxygen free radical accumulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What increases arterial sensitivity to vasoconstrictors such as angiotensin II?. ### Response: oxygen free radical accumulation.

What limitations limited the committee’s ability to establish the most app ropriate test thresholds?

thresholds reported by the included studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What limitations limited the committee’s ability to establish the most app ropriate test thresholds?. ### Response: thresholds reported by the included studies.

The committee decided to contact study authors seeking additional data at what threshold?

particular thresholds

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The committee decided to contact study authors seeking additional data at what threshold?. ### Response: particular thresholds.

What did the committee limit this request to?

data on NT -proBNP r ather than BNP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the committee limit this request to?. ### Response: data on NT -proBNP r ather than BNP.

NT -proBNP has a greater sensitivity over a range of thresholds than what?

BNP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: NT -proBNP has a greater sensitivity over a range of thresholds than what?. ### Response: BNP.

What is the name of the book that treats heart failure?

Chronic Heart Failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the book that treats heart failure?. ### Response: Chronic Heart Failure.

What is CKD?

Chronic kidney disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CKD?. ### Response: Chronic kidney disease.

What is CKD defined by?

a reduction in glomerular filtration rate (eGFR) to <60 ml/min/1.73 m2 and/or persistent albuminuria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CKD defined by?. ### Response: a reduction in glomerular filtration rate (eGFR) to <60 ml/min/1.73 m2 and/or persistent albuminuria.

What is chronic kidney disease defined by a reduction in eGFR to 60 ml/min/1.73 m2?

at least stage 3A

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is chronic kidney disease defined by a reduction in eGFR to 60 ml/min/1.73 m2?. ### Response: at least stage 3A.

Chronic kidney disease is a common and important comorbidity in peop le with heart failure that confers significant additional risks of mortality?

Adults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Chronic kidney disease is a common and important comorbidity in peop le with heart failure that confers significant additional risks of mortality?. ### Response: Adults.

What is heart failure associated with?

chronic kidney disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is heart failure associated with?. ### Response: chronic kidney disease.

What is the eGFR3 0 ml/min/1.73 m2?

severe CKD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the eGFR3 0 ml/min/1.73 m2?. ### Response: severe CKD.

How have people with severe CKD been excluded from trials of heart failure pharmacotherapies?

randomised controlled trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How have people with severe CKD been excluded from trials of heart failure pharmacotherapies?. ### Response: randomised controlled trials.

What type of CKD can limit the ability to introduce and/or adequately up -titrate heart failure medications?

HFREF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of CKD can limit the ability to introduce and/or adequately up -titrate heart failure medications?. ### Response: HFREF.

What is eGFR 31 -59 ml/min/1.73 m2?

The presence of even m ild or moderate CKD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is eGFR 31 -59 ml/min/1.73 m2?. ### Response: The presence of even m ild or moderate CKD.

What are nephrotoxic medications often reduced or discontinued in people with worsening renal function?

heart failure medications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are nephrotoxic medications often reduced or discontinued in people with worsening renal function?. ### Response: heart failure medications.

People with CKD are more prone to develop adverse effects related to what?

their heart failure medication

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: People with CKD are more prone to develop adverse effects related to what?. ### Response: their heart failure medication.

Hyperkalaemia and hypotension are two of the adverse effects of heart failure medication.

risks and cost effectiveness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Hyperkalaemia and hypotension are two of the adverse effects of heart failure medication.. ### Response: risks and cost effectiveness.

What is the term for a mild side effect that can be significant in the long term?

worsening renal function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the term for a mild side effect that can be significant in the long term?. ### Response: worsening renal function.

What are two other side effects that can occur with heart failure medications?

hyperkalaemia and hypotension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are two other side effects that can occur with heart failure medications?. ### Response: hyperkalaemia and hypotension.

What may be underutilized in people with heart failure who also have CKD?

evidence -based pharmacotherapies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be underutilized in people with heart failure who also have CKD?. ### Response: evidence -based pharmacotherapies.

What is the most common type of HFREF?

CKD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the most common type of HFREF?. ### Response: CKD.

What is a potentially life-saving disease-modifying medication?

albuminuria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a potentially life-saving disease-modifying medication?. ### Response: albuminuria.

What was highlighted as an important area to review when considering the update of this guideline?

heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was highlighted as an important area to review when considering the update of this guideline?. ### Response: heart failure.

What are the benefits, risks and cost effectiveness of pharmacological interventions for heart failure in people with heart failure who also have CKD?

similar clinical

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the benefits, risks and cost effectiveness of pharmacological interventions for heart failure in people with heart failure who also have CKD?. ### Response: similar clinical.

What is the PICO characteristic of review question Population Adults with heart failure and chronic kidney disease who are not on dialysis?

at least stage 3A / eGFR <60 mL/min

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the PICO characteristic of review question Population Adults with heart failure and chronic kidney disease who are not on dialysis?. ### Response: at least stage 3A / eGFR <60 mL/min.

eGFR 60 mL/min) who are not on dialysis?

risks and cost effectiveness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: eGFR 60 mL/min) who are not on dialysis?. ### Response: risks and cost effectiveness.

What is ACE?

Angiotensin Converting Enzyme

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ACE?. ### Response: Angiotensin Converting Enzyme.

Angiotensin Receptor Antagonist/ Blocker (ARB)?

risks and cost effectiveness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Angiotensin Receptor Antagonist/ Blocker (ARB)?. ### Response: risks and cost effectiveness.

What is the acronym for Receptor Antagonist?

Mineralocorticoid

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for Receptor Antagonist?. ### Response: Mineralocorticoid.

Digoxin and Diuretics are loop and loop related.

risks and cost effectiveness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Digoxin and Diuretics are loop and loop related.. ### Response: risks and cost effectiveness.

Ivabradine and Sacubitril -Valsartan are what?

Hydralazine -Nitrate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Ivabradine and Sacubitril -Valsartan are what?. ### Response: Hydralazine -Nitrate.

Hydralazine -Nitrate is what type of drug?

Diuretics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Hydralazine -Nitrate is what type of drug?. ### Response: Diuretics.

What was the HR of patients in the lower 2 risk tertiles?

1.12

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the HR of patients in the lower 2 risk tertiles?. ### Response: 1.12.

What did the results of the TIMACS trial suggest?

superior outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the results of the TIMACS trial suggest?. ### Response: superior outcome.

What was reduced by early rather than delayed inter-vention in the setting of UA/NSTEMI?

refractory is-chemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was reduced by early rather than delayed inter-vention in the setting of UA/NSTEMI?. ### Response: refractory is-chemia.

What were the risks of death, MI, and stroke among patients at the early approach?

highest tertileof ischemic risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the risks of death, MI, and stroke among patients at the early approach?. ### Response: highest tertileof ischemic risk.

What did the GRACE risk score define among patients at the highest tertileof ischemic risk?

risksof death, MI, and stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the GRACE risk score define among patients at the highest tertileof ischemic risk?. ### Response: risksof death, MI, and stroke.

What was used to assess if a more aggressive strategy of very earlyintervention would lead to better outcomes in patients with non-ST-elevation ACS?

ABOARD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was used to assess if a more aggressive strategy of very earlyintervention would lead to better outcomes in patients with non-ST-elevation ACS?. ### Response: ABOARD.

What did the ABOARD study compare angiography and intervention per-formed immediately on?

presentation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the ABOARD study compare angiography and intervention per-formed immediately on?. ### Response: presentation.

How many patients with unstable ischemic symptoms were randomized?

352

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with unstable ischemic symptoms were randomized?. ### Response: 352.

How long after enrollment were patients randomized to immediate or delayed angiography and revascularization?

70 minutes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after enrollment were patients randomized to immediate or delayed angiography and revascularization?. ### Response: 70 minutes.

What was the loading dose of clopi-dogrel?

/H11350300 mg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the loading dose of clopi-dogrel?. ### Response: /H11350300 mg.

How many hospitals had patients with unstable ischemic symptoms randomized?

13

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many hospitals had patients with unstable ischemic symptoms randomized?. ### Response: 13.

What was the primary trial endpoint during thehospitalization period?

peak troponin I value

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the primary trial endpoint during thehospitalization period?. ### Response: peak troponin I value.

What did immediate intervention confer with regard to the primary endpoint?

noadvantage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did immediate intervention confer with regard to the primary endpoint?. ### Response: noadvantage.

In the immediate and delayed intervention groups, what was the mediantroponin I value?

2.1 versus 1.7 ng/mL

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In the immediate and delayed intervention groups, what was the mediantroponin I value?. ### Response: 2.1 versus 1.7 ng/mL.

What was the mean ng/mL in the immediate and delayed intervention groups?

1.7

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the mean ng/mL in the immediate and delayed intervention groups?. ### Response: 1.7.

What was there a trend toward in the prespecifiedclinical secondary endpoint of death, MI, or urgent revascu-larization by 1 month?

improved outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was there a trend toward in the prespecifiedclinical secondary endpoint of death, MI, or urgent revascu-larization by 1 month?. ### Response: improved outcome.

How many trials did these 3 trials provide support for?

107,122,123

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many trials did these 3 trials provide support for?. ### Response: 107,122,123.

What is the GRACE score for high risk patients?

/H11022140

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the GRACE score for high risk patients?. ### Response: /H11022140.

What is the GRACE score?

/H11022140

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the GRACE score?. ### Response: /H11022140.

What is reasonable in low- to intermediate-risk patients?

a more delayed approach

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable in low- to intermediate-risk patients?. ### Response: a more delayed approach.

When is the “early” time period?

within the first 24 hours after hospital presentation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When is the “early” time period?. ### Response: within the first 24 hours after hospital presentation.

What is derived by angiography and intervention performed within the first fewhours of hospital admission?

reduce ischemic complications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is derived by angiography and intervention performed within the first fewhours of hospital admission?. ### Response: reduce ischemic complications.

What advantage of early intervention was achieved in the context of intensive background antithrom-botic therapy?

noadvantage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What advantage of early intervention was achieved in the context of intensive background antithrom-botic therapy?. ### Response: noadvantage.

What is the acronym for transcatheter aortic valve implantation?

TAVI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for transcatheter aortic valve implantation?. ### Response: TAVI.

How was the heterogeneity of the pooled results assessed?

using the Higgins ’I2and the c2tests

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was the heterogeneity of the pooled results assessed?. ### Response: using the Higgins ’I2and the c2tests.

What was a Higgins 'I2value of $50% or c2P.05 considered to represent?

signi ﬁcant heterogeneity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was a Higgins 'I2value of $50% or c2P.05 considered to represent?. ### Response: signi ﬁcant heterogeneity.

The overall certainty of the evidence was assessed for each important outcome of interest using what?

GRADE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The overall certainty of the evidence was assessed for each important outcome of interest using what?. ### Response: GRADE.

What is GRADE?

Gradingof Recommendations, Assessment, Development, and Evaluation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is GRADE?. ### Response: Gradingof Recommendations, Assessment, Development, and Evaluation.

How were evidence pro files created?

using the GuidelineDevelopment Tool

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How were evidence pro files created?. ### Response: using the GuidelineDevelopment Tool.

What did the GuidelineDevelopment Tool categorize?

1 of 4 levels: high, moderate, low, or very low

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the GuidelineDevelopment Tool categorize?. ### Response: 1 of 4 levels: high, moderate, low, or very low.

How were recommendations graded according to CHEST's grading system?

theGRADE approach

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How were recommendations graded according to CHEST's grading system?. ### Response: theGRADE approach.

What did CHEST use to grade recommendations?

GRADE approach

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did CHEST use to grade recommendations?. ### Response: GRADE approach.

What do Strongrecommendations use the wording "we recommend"?

”

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do Strongrecommendations use the wording "we recommend"?. ### Response: ”.

What does "we suggest" do?

account for patient values and preferences regarding these outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does "we suggest" do?. ### Response: account for patient values and preferences regarding these outcomes.

The implications of the strength of recommendation are summarized in what?

e-Table 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The implications of the strength of recommendation are summarized in what?. ### Response: e-Table 2.