json
dict
jpg
imagewidth (px)
49
4.1k
__key__
stringlengths
6
6
__url__
stringclasses
29 values
{ "caption": "Cerebrospinal fluid flow despite central spinal cord compression in an 11-month-old girl. Axial T2 (a), sagittal T2 (b) and phase contrast Cerebrospinal fluid (CSF) flow sequence (c) shows central hypertrophy of the foramen magnum (arrows) compressing the spinal cord (a, b) and CSF flow anteriorly and laterally to the cord on phase contrast imaging (c)", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271114-1-247_2022_5348_Fig6_HTML.jpg" }
008900
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Sagittal T2 magnetic resonance images of the craniocervical junction in a girl with achondroplasia at 1 month (a) and 9 months (b) of age. The images show interval progression of stenosis from Grade 3 to Grade 4 due to occipital hypertrophy, which indents the spinal cord (arrow)", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271114-2-247_2022_5348_Fig7_HTML.jpg" }
008901
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "The effect of cerebrospinal fluid (CSF) flow void on achondroplasia foramen magnum score (AFMS): Sagittal (a) and axial (b, c) magnetic resonance images of the craniocervical junction in a 4-month-old girl with achondroplasia. Normal high signal CSF is seen above and below the foramen magnum. CSF flow void (arrows) anterior to the spinal cord is indistinguishable from the cortex of adjacent bone on T2 sequences (a, b). In contrast, CSF signal (arrow) is clearly present on the gradient echo sequence (c). CSF flow void (a, b) may lead to the assignment of a higher AFMS score than is warranted", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271114-3-247_2022_5348_Fig4_HTML.jpg" }
008902
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Sagittal T2 magnetic resonance images of the craniocervical junction in a 12-year-old girl with achondroplasia. There is subtle increased T2 signal (arrow) without evidence of foramen magnum stenosis", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271114-5-247_2022_5348_Fig5_HTML.jpg" }
008903
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "A sagittal T2 magnetic resonance image of the craniocervical junction in a 7-year-old girl with achondroplasia. T2 signal change is present in the cervical cord (arrow) without evidence of foramen magnum stenosis", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271114-6-247_2022_5348_Fig2_HTML.jpg" }
008904
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Thioflavin-S-positive staining (green) and DAPI (blue) in the 5XFAD hippocampus and cerebral cortex for Control, Mem and UB-ALT-EV(a). Quantification of Thioflavin-S positive staining in 5XFAD mice hippocampus (b) and cortex (c). Average Size of Thioflavin-S plaques measurement (d). Levels of amyloid-β40 levels (e). Levels of amyloid-β42 (f). Ratio of amyloid-β42/amyloid-β40 (g). Values are the mean ± Standard error of the mean (SEM); (n = 3 for each group). A standard one-way ANOVA followed by Tukey post hoc analysis was performed. #p < 0.05; ##p < 0.01 for Mem or UB-ALT-EV vs. Control", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271115-6-18_2022_4438_Fig5_HTML.jpg" }
008905
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Image quality analysis. a, b Real time and conventional MR images in short axis orientation. a Standard cine images (conventional cine balanced SSFP sequence, planes 6 and 9) and RT images (RT balanced SSFP sequence, planes 6 and 9) of 7-, 14- and 16-year-old patients no. 4, 12, 18, (female, male, male), were rated good = 3 and excellent = 4 on average for structure visualization based on established 4-point scales [13, 15]. b The most common artifacts were metallic artifacts (e.g., sternal clips) (arrows), which affected standard cine MRI significantly more often and more severely than RT-MRI. Images of 11-year-old patient no. 9 (female). Respiratory artifacts (stars) occurred more often with cine MRI whereas RT-MRI was not affected by respiratory ghosting. Images of 5-year-old patient no. 19 (female). MRI magnetic resonance imaging, RT real-time, RT-MRI real-time magnetic resonance imaging, SSFP steady-state free precession", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271116-2-247_2022_5327_Fig2_HTML.jpg" }
008906
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Representative images of the youngest patient, a 5-year-old girl (patient 19) falling asleep during RT-MRI. Images in short axis orientation from basal (plane 8), mid-ventricular (plane 11) and apical (plane 15) levels are presented at end-diastole and end-systole for RT-MRI (RT balanced SSFP sequence) and corresponding cine MRI (conventional cine balanced SSFP sequence). RT-MRI showed excellent image quality. In contrast, cine MRI suffered from respiratory ghosting. Arrows mark respiratory artifacts. MRI magnetic resonance imaging, RT-MRI real-time magnetic resonance imaging, SSFP steady-state free precession", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271116-4-247_2022_5327_Fig3_HTML.jpg" }
008907
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Sagittal section of medial femoral condyles was divided in three zone of interest (1. anterior, 2. central, and 3. posterior). The red dotted line shows the weight-bearing area of the medial femoral condyle", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271147-0-40634_2022_501_Fig3_HTML.jpg" }
008908
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Representative image of meniscal root remnant after 16-weeks of partial meniscectomy", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271147-2-40634_2022_501_Fig2_HTML.jpg" }
008909
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Hematoxylin eosin (5A, 5B) and alcian blue staining (5C) of articular cartilage samples. The cartilage shows a normal appearance, the surface is smooth, chondrocytes are present throughout, and the matrix staining is homogeneous in the control knee (5A). The superficial and intermediate layers of cartilage are lost, and matrix vertical fissures reach the deep radial zone in this sample corresponding to an ulcer at the weight bearing area from an OA knee in animals subjected to meniscal root injury and partial meniscectomy (5 B, C). Cellularity is diminished and the normal pattern of distribution in columns is lost. Cartilage matrix is loss with delamination and excavation of superficial and mid layer (5B, C). Marked structural abnormalities and hypocellularity are also evident. Matrix staining intensity is severely reduced (× 20)", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271147-3-40634_2022_501_Fig5_HTML.jpg" }
008910
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Alcian blue staining of weight bearing articular cartilage sample showing reduction of matrix staining intensity and breached tidemark by blood vessels and with minor splits (red arrows) compromising the integrity of the junction between the calcified and the noncalcified cartilage", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271147-4-40634_2022_501_Fig6_HTML.jpg" }
008911
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Meniscectomy was performed by transecting the medial meniscus posterior root with a radial cut (PCL, posterior cruciate ligament; MMPR, medial meniscus posterior root)", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271147-5-40634_2022_501_Fig1_HTML.jpg" }
008912
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Comparative radiographic images just before (9A) and after 16-weeks post-surgery (9B) showing medial joint space narrowing", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271147-6-40634_2022_501_Fig7_HTML.jpg" }
008913
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "a Single-molecule FISH (smFISH) image of XIST long non-coding RNA (lncRNA) in the nucleus of an HEK293 cell before expansion (the white line denotes the nuclear envelope). b As in a, using Expansion Fluorescence In Situ Hybridization (ExFISH). Scale bars, 2 μm (6.6 μm).(Reprinted/adapted by permission from Springer Nature: Chen et al. [59], copyright 2016)", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271151-0-40580_2022_318_Fig8_HTML.jpg" }
008914
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Anchoring and labeling of proteins using acrydite-modified oligonucleotides (oligos) in the original ExM protocol. a Chemical structure of the acrydite-modified oligo. b Schematic of microtubules (green) and hydrogel network (orange). c The acrydite-modified oligo (shown in a) hybridized to a oligo-bearing secondary antibody (gray, top), bound via the primary antibody (gray, bottom) to the microtubules (purple). The acrydite-oligo is incorporated into the gel (orange lines) via the methacryloyl group (orange dot) and remains anchored after the removal of  the microtubules and antibodies by proteolysis (dotted lines). d Pre-expansion widefield fluorescence image of Thy1-YFP mouse brain slice. Scale bar, 500 μm. e Post-expansion widefield image of the same sample in d. Scale bar, 500 μm (2.01 mm). f, g Confocal fluorescence image of the boxed regions in d and e, respectively. Scale bars, 5 μm (20.1 μm) h, i Confocal fluorescence image of the boxed regions in f and g, respectively. Scale bars, 2.5 μm (10.0 μm).(From Chen et al. [34]. Reprinted/adapted by permission from AAAS)", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271151-1-40580_2022_318_Fig7_HTML.jpg" }
008915
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Expansion of Thy1-YFP-H mouse brain slice using MA-NHS as the protein anchor. a Triple-color proExM of endogenously expressed YFP (blue), immunostained presynaptic marker Bassoon (green), and immunostained postsynaptic marker Homer1 (red). Scale bar, 5 μm. b The same area as in a after expansion. Scale bar, 5 μm. c, d Magnified views of the boxed regions before expansion. Scale bars, 500 nm. e, f The same area in c and d after expansion. Scale bars, 500 nm. g, h Cross-sectional profiles of the boxed regions in e and f (arb., arbitrary units).(Reprinted/adapted by permission from Springer Nature: Chozinski et al. [38], copyright 2016)", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271151-11-40580_2022_318_Fig5_HTML.jpg" }
008916
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "High-resolution images obtained with high-expansion-factor ExM variants. a Nucleus imaged by confocal microscopy after TREx. Scale bar, 1 μm. b High-resolution view of several nuclear pores from boxed region (2) of a and the distribution of diameters of individual nuclear pores. Scale bar, 200 nm. c Immunostainings for the peroxisome membrane protein Pmp70 in neurons by both super-resolution and X10 Expansion Microscopy. Scale bar, 100 nm. d The exemplary line scan from the X10 Expansion Microscopy image in c is shown with a best Gaussian fit curve. e Quantification of the average resolution of X10 Expansion Microscopy image, which is 25.2 ± 0.2 nm. f pan-ExM reveals nuclear architecture in interphase. Image of SYTOX Green nucleic acid stain (middle column) and NHS ester pan-stained sample (left column) and overlay of them (right column). Scale bars, (top row) 5 μm, (middle row) 250 nm, (bottom row), 1 μm. g Overlay of the NHS ester and anti-GFP images. The insets show the zoom-in yellow boxes and reveal individual ManII-positive Golgi cisternae. Scale bars, 2 μm. h Label-retention expansion STORM (LR-ExSTORM) image of a HeLa cell overexpressing SNAP-CLTB, stained with BG-MA-biotin, and post expansion labeled with streptavidin-AF647. Scale bar, 2 μm. i, j Images of x–y cross sections at the top of single CCPs as illustrated in m. Scale bar, 100 nm. k, l Images of x–y cross sections in the middle of single CCPs as illustrated in n. Images in i–l are different CCPs. Scale bar, 100 nm. o Nearest cluster distance analysis of 134 CCPs imaged with LR-STORM. p Expansion Revealing (ExR) reveals co-localized clusters of Aβ42 peptide and potassium ion channels in the fornix of Alzheimer’s model 5× FAD mice. The image showing post-expansion Aβ42 (magenta), SMI (cyan) and Kv7.2 (yellow) staining in the fornix of a 5xFAD mouse (Scale bar, 400 nm). The left most panel, merged low magnification image (Scale bar, 4 μm).(a, b Reprinted/adapted from Damstra et al. [48]. c–e Reprinted/adapted from Truckenbrodt et al. [49]. f, g Reprinted/adapted from M’Saad et al. [47]. h–o Reprinted/adapted by permission from Rockefeller University Press: ©2021 Shi et al. [55]. Originally published in J. Cell. Biol. 10.1083/jcb.202105067. p Reprinted/adapted from Sarkar et al. [52] by permission from the author)", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271151-13-40580_2022_318_Fig15_HTML.jpg" }
008917
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Protein-retention ExM (proExM) of HeLa cells using acryloyl-X, SE (AcX) as the protein anchor. a Dual-color proExM of clathrin (fused to mEmerald, green) and keratin (mRuby2, red). Two representative images are shown. Scale bar, 1 μm (4.3 μm; here and after, physical size after the expansion, if available, is shown in brackets). b Dual-color proExM image of actin (mRuby2, red) and paxillin (mEmerald, green) fusions. Insets are magnified views of the boxed regions. Scale bars, 5 μm (21.5 μm) and 1 μm (4.3 μm, insets).(Reprinted/adapted by permission from Spring Nature: Tillberg et al. [37], copyright 2016)", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271151-14-40580_2022_318_Fig3_HTML.jpg" }
008918
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Combining proExM and lattice light sheet microscopy achieves whole-brain imaging of Drosophila with sub-100 nm resolution. Scale bar, 100 μm.(From Gao et al. [70]. Reprinted/adapted by permission from AAAS)", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271151-15-40580_2022_318_Fig4_HTML.jpg" }
008919
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Click-ExM imaging of proteins, nucleic acids and small molecules. a Chemical structure of EdU, and pre- and post-click-ExM images of nascent DNA (AF488) in EdU-treated HeLa cells. Scale bar, 5 μm. b Chemical structure of EU, and pre- and post-click-ExM images of nascent RNA (AF555) in EU-treated HeLa cells. Scale bar, 5 μm. c Chemical structure of Az-afatinib, and pre- and post-click-ExM images of HeLa cells treated with Az-afatinib (AF555). Scale bars, 10 μm. d Chemical structure of OP-Puro, and pre- and postc-lick-ExM images of nascent peptides (AF488) in OP-Puro-treated HeLa cells. Scale bar, 10 μm. e Chemical structure of Alk-Hoechst, and pre- and post-click-ExM images of DNA (AF488) in Alk-Hoechst-labeled HeLa cells. AcX was used for anchoring. Scale bar, 5 μm. All the scale bars are in the pre-expansion dimension.(Reprinted/adapted by permission from Springer Nature: Sun et al. [66], copyright 2021)", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271151-16-40580_2022_318_Fig12_HTML.jpg" }
008920
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Membrane expansion microscopy (mExM) of fixed brain tissue. a Six serial sections from a 3D image stack obtained on a confocal spinning-disk microscope. Axons can be identified by their high contrast due to the increased concentration of lipids in the myelin sheaths (red arrows). Scale bar, 10 μm. b mExM processed tissue imaged with light-sheet microscopy. Scale bar, 10 μm.(Reprinted/adapted from Karagiannis et al. [62] by permission from the author)", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271151-2-40580_2022_318_Fig11_HTML.jpg" }
008921
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "RNA detection by combining ExM and hybridization chain reaction (HCR) v3.0 using a TRITON linker. a Pre-expansion image of PGK1 transcripts. b Magnified view of the boxed region in a. c Post-expansion image of the same cell. d Magnified view of the boxed region in c. Scale bars, 50 μm (a, c) and 10 μm (b, d).(Reprinted/adapted with the permission from Wen et al. [40]. Copyright 2021 American Chemical Society)", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271151-6-40580_2022_318_Fig10_HTML.jpg" }
008922
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "High-grade dysplasia - revealed marked nuclear enlargement, hyperchromasia, membrane irregularity, and apoptosis with significant loss of polarity (H&E, x100)Inset 3a shows intestinal metaplasia (yellow arrow) in the form of scattered goblet cells with basal pseudostratification of nuclei (H&E, x400).", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271173-0-cureus-0014-00000025805-i03.jpg" }
008923
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Intracholecystic papillary neoplasm (ICPN) and intraluminal growth of back-to-back epithelial units in a papillary or tubulopapillary configuration (H&E, x100)Inset 4a shows a high-power view (H&E, x400).", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271173-1-cureus-0014-00000025805-i04.jpg" }
008924
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Adenocarcinoma - tumor cells formed irregular glands and papillae of variable size and shape with angulated contours in the desmoplastic stroma (H&E, x100)Inset 5a shows perineural invasion (yellow arrow) (H&E, x400)", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271173-2-cureus-0014-00000025805-i05.jpg" }
008925
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Low-grade dysplasia - confinement of the columnar cells toward the basal aspect of the epithelium with a mild nuclear enlargement (H&E, x100)Inset 2a shows nuclear pseudostratification, hyperchromasia, chromatin clumping, and irregular nuclear membrane (H&E, x 400)", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271173-3-cureus-0014-00000025805-i02.jpg" }
008926
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Carcinosarcoma - exhibiting carcinomatous (red arrow) and sarcomatous areas (yellow arrow) (H&E, x400)", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271173-5-cureus-0014-00000025805-i06.jpg" }
008927
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Development of GERI mice for imaging Arc mRNA. (A) Schematic for labeling Arc mRNA in vivo. NLS, nuclear localization sequence; Pol II, RNA polymerase II. Gray boxes, UTR; red boxes, Arc coding sequence [Arc-CDS]; blue boxes, 24× PBS cassette; black lines, introns. The Arc-PBS knockin (KI) mouse was crossed with the PCP-GFP mouse to generate PCP×PBS hybrids. (B) On day 1, mice were removed from their home cage (H) and immediately anesthetized for in vivo imaging. On day 2, the mice were subjected to CFC followed by in vivo imaging. (C, Left) Experimental setup for in vivo two-photon imaging through a hippocampal window. (C, Right) Coronal view of the brain of a PCP×PBS mouse after hippocampal window surgery. (D) Representative in vivo image of CA1 neurons in a PCP×PBS mouse after autofluorescence subtraction (for detailed image-processing procedures, see SI Appendix, Fig. S2). The same region (dotted box) is enlarged for comparison of images taken on day 1 (H) and day 2 (CFC). Arc TSs are marked with red arrowheads. (E) Arc mRNA detected by two-color smFISH targeting Arc-CDS (green) and PBS (magenta). (F) Time-lapse images of an Arc+ neuron after CFC. (G) Fraction of Arc+ neurons over time after CFC. (H) Fraction of Arc+ neurons in CA1 after H and CFC conditions (n = 12 mice; ***P < 10−4 by pairwise t test). (Scale bars, 1 mm [C], 50 μm [D and E], and 10 μm [F].) Error bars represent the SEM.", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271212-0-pnasp2117076119fig01.jpg" }
008928
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Ruptured bullae on the anterolateral aspect of the right shin in various stages of healing. Lichenified skin on the distal lower extremity can be noted", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271213-0-cureus-0014-00000025806-i03.jpg" }
008929
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Brain-wide density map of nNOS neurons and their subtypes(A) Heatmaps demonstrating the distribution of total nNOS and nNOS subtype populations. See also Video S3 and Table S5.(B) Representative raw images of nNOS, nNOS/NPY, nNOS/SST, nNOS/PV, and nNOS/VIP neurons in the olfactory bulb, hippocampus, medial amygdala (MEA), dorsomedial hypothalamus (DMH), and cerebellum. Reference atlas images included in nNOS/VIP images show the area displayed for each region of interest. MOB, main olfactory bulb; CA1, Ammon’s horn; DG, dentate gyrus; opt, optic tract; fx, fornix; gr, granular; mo, molecular.(C). nNOS density by brain region for the total nNOS neurons and their subtypes. The size of a circle corresponds to density, as shown in the key at the bottom.See Table S5 for full names of abbreviations.", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271215-0-nihms-1818169-f0008.jpg" }
008930
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Heterogeneous vascular arrangements in the isocortex(A–C) Creating an isocortical flatmap.(A) Anatomical border lines of the Allen CCF.(B) Gradient vectors from solving the Laplace equation by setting cortical layer 1 and layer 6 as endpoints.(C) The flattened projected profile.(D) The cortical flatmap with Allen CCF border lines. y axis: bregma anterior-posterior (AP) coordinates; x axis, azimuth coordinate representing the physical distance by tracing the cortical surface on the coronal cut.(E) The averaged vasculature length and branching density as well as vessel radius plotted onto the cortical flatmap. Note the high density of vasculature in the SS (gray arrowhead), auditory (white arrowhead), and retrosplenial (black arrowhead) cortices; there is a low density in the lateral association cortex (white arrow).(F) Examples of cortical areas with different vasculature structures. Large (radius > 5 μm) and small vessels are colored red and green, respectively.(G) Correlation between average vessel density and branching density (top) or average radius (bottom) in the isocortex. See Table S1 for abbreviations.(H) Cortical layer-specific max projection of vasculature length density.(I) Large surface vessels from the left (green) and right (red) hemisphere from two different animals.(J) Large surface vessels from 4 different brains with different colors (red, green, blue, and cyan) in each hemisphere.(K) Large surface and P vessels (8 hemispheres from 4 animals) in a cortical layer-specific flatmap based on their radius.", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271215-4-nihms-1818169-f0003.jpg" }
008931
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Cortical pericyte and nNOS neuron densities display opposite correlation with vascular density(A) Example images of areas showing variability in pericyte density from PDGFRβ-Cre; Ai14 mice with the pericyte detection algorithm (red stars).(B) Cortical flatmap of averaged pericyte density across the isocortex in comparison with the vessel length density.(C) Scatterplot demonstrating significantly positive correlation between pericyte density and vascular length density in isocortical regions (R = 0.859, p = 1.86 × 10−12). See Table S4 for abbreviations.(D) Layer-specific pericyte distribution.(E) Relative pericyte (green) and vessel (red) density (normalized against maximum value within the area) in cortical regions without (left) or with layer 4 (right).(F and G). Averaged density of pan nNOS neurons (F) or nNOS subtypes (G) on the cortical flatmap. Note the higher nNOS density in the medial prefrontal and lateral association areas.(H) Representative STPT images of nNOS cell types from the primary SS cortex and the agranular insular cortex.(I) Scatterplot showing significant negative correlation between total nNOS density and vessel length density in the isocortex (R = −0.806, p = 6.9 × 10−7).(J) Correlation matrix between nNOS cell types and vascular/pericyte measurements. *p < 0.05, **p < 0.005 after Bonferroni correction. (−) denotes negative correlation.", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271215-6-nihms-1818169-f0005.jpg" }
008932
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "High-resolution 3D mapping of the cerebrovasculature, pericytes, and neuronal cell types(A) Fluorescent dye (FITC)-conjugated albumin gel perfusing the mouse brain through the heart to label cerebrovasculature.(B) Combination of physical and optical sectioning to achieve lossless imaging of a sample.(C and D) Stitching with optical aberration and tile line correction (D) from uncorrected images (C).(E–G) Example outputs from each stage of the analysis pipeline. Top row: 100-μm-thick 3D volume from the white boxed areas from the center row. Center row: an example coronal section. Bottom row: whole-brain results.(E) The raw image volume of FITC-labeled vasculature.(F) The binarized vasculature.(G) The traced vasculature. Large (radius > 5 μm) and small vessels are colored red and green, respectively. The bottom image shows the vasculature density.(H–J) The averaged vasculature length density (H), branching density (I), and radii (J) from four C57bl/6 mouse brains.(K and L). The correlation between vessel density and branching density (K) and the correlation between vessel density and the averaged radius (L). The size of each ROI is displayed according to the relative volume of the area. See Table S1 for abbreviations.(M–O). Pericyte density mapping. Shown is an example of tdTomato labeling from PDGFRβ-Cre; Ai14 mice (M), a pericyte detection algorithm (red stars, N), and brain-wide pericyte density (n = 10 brains) (O).(P–R) Pan nNOS neuronal mapping using nNOS-CreER; Ai14 mice (n = 10 brains). Shown is artificial intelligence (AI)-based detection of nNOS cells with two distinct shapes (green and red crosses) in the cerebellum (P, from the white box in Q) and brain-wide nNOS density (R).", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271215-7-nihms-1818169-f0002.jpg" }
008933
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "A. Dermal-based lymphoid infiltrate with focal evidence of epidermotropism (H&E, 200x). B. Epidermal lymphocytes with irregular nuclear contours and clear cytoplasm (arrows) (H&E, 400x). C. CD3 immunohistochemical stain highlighting T-cells, which account for most of the lymphoid infiltrate (200x). D. CD4 immunohistochemical stain highlighting the majority of the T-cells, as well as dimly staining dendritic cells and macrophages (200x). E. CD7 immunohistochemical stain showing partial loss of expression in the T-cells (200x). F. CD8 immunohistochemical stain showing background cytotoxic T-cells, fewer in number than CD4-positive cells (200x).", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271217-0-cureus-0014-00000025809-i02.jpg" }
008934
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "A. Right shin eruption at presentation; B. After one month of terbinafine", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271217-1-cureus-0014-00000025809-i01.jpg" }
008935
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Inflammatory and senescence-related molecules are highly expressed in the SASPase(SASP)high mTEC fraction. (A) The expression of the transcripts of the indicated genes relative to Actb in sorted cTECs, SASPneg, SASPlow and SASPhigh mTECs from SASP-EGFP-KI mice was assessed by quantitative reverse transcription (qRT)–PCR. The means and SE of at least two independent experiments are shown. One-way ANOVA with Tukey post hoc test was performed (*P < 0.05, **P < 0.01, ***P < 0.001). (B) Paraffin-embedded thymus tissues from B6 and NZW mice were stained with an anti-CXCL5 antibody. Arrows indicate CXCL5 expression around the HC areas, with brown coloring representing positive staining. Scale bars, 50 µm. (C) The expression of the transcripts of the indicated genes relative to Actb was assessed by qRT–PCR (left). The means and SE of three independent experiments are shown. One-way ANOVA with Tukey post hoc test was performed (*P < 0.05, ***P < 0.001, NS = not significant). Cryosections of the thymus from adult B6 and NZW mice were assayed for SA-β-gal activity. Arrows indicate blue-colored β-gal-positive HC areas. Scale bars, 20 µm. Data are representative of at least two independent experiments. C, cTECs; –, SASPneg mTECs; L, SASPlow mTECs; H, SASPhigh mTECs.", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271218-3-dxy07302.jpg" }
008936
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "CT scan of the abdomen and pelvis. (A) A coronal section showing ascites (asterisk), the liver is seen without metastatic disease, normal size, and contour. (B) A sagittal section shows a large peritoneal mass (arrow) of 19 x 25 x 11 cm, also seen on (C) the axial section. Arrowhead points toward an incidental calcified fibroid seen in (A) and (B).", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271230-1-cureus-0014-00000025813-i01.jpg" }
008937
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Erythematous nodules over neck.", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271231-0-cureus-0014-00000025812-i04.jpg" }
008938
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Erythematous nodules over chest wall.", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271231-1-cureus-0014-00000025812-i03.jpg" }
008939
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Whole Body PET CT image with PET section of tumour (white arrow head is showing the tumour).", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271231-2-cureus-0014-00000025812-i02.jpg" }
008940
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Biopsy taken from chest wall lesions.", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271231-3-cureus-0014-00000025812-i05.jpg" }
008941
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "H and E slide showing keratinization, nuclear pleomorphism, and cellular dissociation which is suggestive of squamous cell carcinoma (40× with cellular details of biopsy taken from chest wall lesions).", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271231-4-cureus-0014-00000025812-i06.jpg" }
008942
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Whole body PET CT image with CT section of tumour (white arrow head is showing the tumour).", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271231-5-cureus-0014-00000025812-i01.jpg" }
008943
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Difference of plain CT (left) and contrast-enhanced CT (right)", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271246-1-12880_2022_851_Fig2_HTML.jpg" }
008944
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Contour of a representative test case using the five methods. Each column represents a different slice. The ground truth is in red, and the contour using the different methods is in the indicated colors. RR: Green, DR: blue, TCAS + RR: magenta, TCAS + DR: cyan", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271246-2-12880_2022_851_Fig5_HTML.jpg" }
008945
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "KRAB-STAT3 inhibits cell migration and invasion. A, Transwell assay of control and KRAB-STAT3-expressing HeLa and A375 cells. K-S: KRAB-STAT3. Bars = 50 μm. B, Migrated cells per view of control and HeLa cells. C, Migrated cells per view of control and A375 cells represented as mean ± SD; n = 3; Student’s t-test. D, E, Lysosome pH analysis of HeLa and A375 cells. F-G, Mitochondria ROS production detection using mitoSOX, A.U., Any unit. H-I, Mitochondrial membrane potential detection using TFRM. J-K, ATP content in HeLa and A375 cells represented as mean ± SD; n = 3; Student’s t-test", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271252-4-12885_2022_9837_Fig4_HTML.jpg" }
008946
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Cardiac α-actin immunofluorescence. (A) Cardiac α-actin signals (Magenta) on muscle sections from patients and age-matched controls. Laminin appears in Cyan. Scale bar:100 \\documentclass[12pt]{minimal}\n\t\t\t\t\\usepackage{amsmath}\n\t\t\t\t\\usepackage{wasysym} \n\t\t\t\t\\usepackage{amsfonts} \n\t\t\t\t\\usepackage{amssymb} \n\t\t\t\t\\usepackage{amsbsy}\n\t\t\t\t\\usepackage{mathrsfs}\n\t\t\t\t\\usepackage{upgreek}\n\t\t\t\t\\setlength{\\oddsidemargin}{-69pt}\n\t\t\t\t\\begin{document}$$\\upmu $$\\end{document}μm (B) Normal distribution of each fibre intensity for cardiac actin demonstrates an increased cardiac α-actin level in patients 6 and 7 compared with the other patients and the controls. The number of analysed fibres is indicated for each patient. (C) Western blot on muscle extracts shows intense cardiac α-actin bands in patients 7 and 8, and a lower expression in patient 2 and in the controls. Ponceau red served as loading control", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271256-0-40478_2022_1400_Fig8_HTML.jpg" }
008947
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Immunofluorescence of nuclei. Representative images of muscle samples showing an abnormal nuclear shape in patients 6 and 7 compared with the age-matched control as illustrated by the lamin A/C, Nesprin-1, and Nesprin-2 signals. Laminin indicates the basal lamina. The images correspond to a single z-plane after super-resolution of confocal acquisition", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271256-1-40478_2022_1400_Fig7_HTML.jpg" }
008948
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Muscle histology. Gomori trichrome staining on transverse muscle sections evidenced fibre size variability throughout the samples. The images also show an increased interstitial connective tissue in patients 4, 5, 7, 10, and 13 (B, C, E, H, I), abundant cytoplasmic rods in patients 2, 6, 8, 9, and 13 (A, D, F, G, I), cytoplasmic bodies (arrows) in patients 4, 5, 8, and 9 (B, C, F, G), major accumulations of thin filaments in patient 13 (I), as well as intranuclear rods in patient 7 (arrow, highlighted in the inset). In patient 10 (H), no rods or cytoplasmic bodies were observed", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271256-4-40478_2022_1400_Fig2_HTML.jpg" }
008949
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Cytoplasmic and intranuclear rods by electron microscopy. Ultrastructural investigations of the muscle biopsy specimens illustrate cytoplasmic rods with the typical lattice structure in patients 4, 6, and 9 (D, E, F), thin filaments emanating from thickened Z-lines in patients 6 and 9 (arrow) (E, F), numerous intranuclear rods in patients 7 (arrow) and 12 (A, B, C), accumulations of thin filaments in patients 7 (arrow) and 13 (H, I), and major myofibre disorganization in patients 4, 7, and 9 (D, G, H). Note the square shape of the intranuclear rods in patient 12 (B, C)", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271256-6-40478_2022_1400_Fig3_HTML.jpg" }
008950
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Histopathology and immunohistochemistry of patient 1 showing esophageal mass: upper GI endoscopy and biopsy. Histiocytoid tumor cells in an inflammatory background (low-power view).", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271260-1-cureus-0014-00000025814-i01.jpg" }
008951
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Histiocytic cells with high MIB%.", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271260-2-cureus-0014-00000025814-i04.jpg" }
008952
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Histiocytic cells are CD68 positive (IHC, x400).", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271260-4-cureus-0014-00000025814-i02.jpg" }
008953
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Pre-treatment PET-CT scan showing localized, unresectable lower thoracic esophageal mass", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271260-5-cureus-0014-00000025814-i05.jpg" }
008954
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Axial CT image demonstrating a right retroperitoneal hematoma in the region of the right adrenal gland measuring 106.6 mm x 58.1 mm. There are areas of enhancement on arterial phase imaging, which represent congestion of a draining vein or delayed active extravasation.", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271269-0-cureus-0014-00000025821-i01.jpg" }
008955
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Transthoracic echocardiogram, apical four chamber view.", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271271-3-cureus-0014-00000026713-i02.jpg" }
008956
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Incomplete preantorbital ramus of left maxilla of Eotyrannus lengi IWCMS: 1997.550.(A) Lateral view; (B) medial view; (C) ventral view showing alveoli and ventral surface of maxillary shelf; (D) oblique dorsomedial view to show the five (presumably pneumatic) crater-like concavities; (E) oblique posterolateral view to show anatomy of antorbital fossa margin; (F) medial view to emphasise form of the only distinct interdental plates; (G) anterior view; (H) detail of medial surface to show maxillary shelf; (I) lateral surface with majority of neurovascular foramina and their associated furrows emphasised. alv alveoli, bnr base of nasal ramus, intpl interdental plates, maf margin of antorbital fossa, ms maxillary shelf, nefo neurovascular foramina. Images (C) and (G) were kindly provided by Roger Benson.", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271276-1-peerj-10-12727-g004.jpg" }
008957
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Dorsal and sacral vertebrae of Eotyrannus lengi IWCMS: 1997.550.(A) Centrum possibly representing 3rd, 4th or 5th dorsal vertebra in anterior view; (B) left lateral view; (C) ventral view; (D) posterior view; (E) right lateral view; (F) dorsal view; (G) second, less complete dorsal centrum in possible anterior view; (H) possible left lateral view; (I) ventral view; (J) possible posterior view; (K) possible right lateral view; (L) dorsal view; (M) middle dorsal centrum in presumed anterior view; (N) presumed left lateral view; (O) ventral view; (P) presumed posterior view; (Q) presumed right lateral view; (R) dorsal view; (S) probable posterior dorsal centrum in possible anterior view; (T) possible left lateral view; (U) ventral view; (V) possible posterior view; (W) possible right lateral view; (X) dorsal view; (Y) fragmentary unidentified dorsal centrum in ventral view; (Z) possible anterior view; (A′) possible posterior view; (B′) fragmentary unidentified dorsal centrum in ventral view; (C′) oblique probable posterolateral view; (D′) probable posterior view; (E′) sacral vertebra in anterior view; (F′) left lateral view; (G′) ventral view; (H′) posterior view; (I′) right lateral view; (J′) dorsal view; (K′) incomplete neural arch in anterior view; (L′) lateral view; (M′) probable fragment of transverse process, as visible in cross-section at break. latfo lateral fossa, lsp lateral subcircular pit, nc neural canal, rag radiating groove, rar radiating ridge, vk ventral keel.", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271276-10-peerj-10-12727-g015.jpg" }
008958
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Pedal phalanges of Eotyrannus lengi IWCMS: 1997.550.(A) Probable right II-1 in dorsal view; (B) lateral view; (C) distal view; (D) ventral view; (E) probable right IV-3 or IV-4 in lateral view; (F) dorsal view; (G) distal view; (H) medial view; (I) ventral view; (J) proximal view; (K) pedal phalanx of undetermined identity (preserved on same block as left humerus) in dorsal view; (L) lateral or medial view; (M) incomplete pedal ungual in lateral or medial view. clgr claw groove, prdp proximodorsal process, pdr proximal dividing ridge.", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271276-13-peerj-10-12727-g030.jpg" }
008959
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Premaxillary and lateral teeth of Eotyrannus lengi IWCMS: 1997.550.(A) Premaxillary tooth in lingual view; (B) oblique lingual view; (C) tip of premaxillary tooth in lingual view; (D) unidentified lateral tooth in lingual or labial view; (E) distal carina of lateral tooth; (F) tip of in-situ maxillary tooth in lingual view (the same tooth is visible in place on the maxilla in Fig. 4); (G) tip of in-situ dentary teeth. Images (A)–(C) and (F)–(G) were kindly provided by Christophe Hendrickx.", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271276-18-peerj-10-12727-g013.jpg" }
008960
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Scapulae of Eotyrannus lengi IWCMS: 1997.550.(A) Partial shaft of left scapula in lateral view, as preserved in matrix; (B) reconstructed left scapula combining segment of shaft shown in (A) with reconstructed shape of dorsal end, and ventral region including acromion and partial glenoid. (C) Incomplete shaft of right scapula in lateral view. acrp acromion process.", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271276-23-peerj-10-12727-g017.jpg" }
008961
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Humeri of Eotyrannus lengi IWCMS: 1997.550.(A) Right humerus in posterior view; (B) anterior view; (C) lateral view; (D) proximal view; (E) medial view; (F) proximal part of right humerus in medial view; (G) proximal part of left humerus in lateral iew; (H) distal part of right humerus in anterior view; (I) distal part of right humerus in oblique view to show concave area in middle of distal end; (J) distal part of right humerus in posterior view; (K) distal part of right humerus in lateral view; (L) distal end of right humerus, anterior toward top of page; (M) cross-sectional view of shaft of right humerus to show internal cavities. dpc deltopectoral crest, ent entepicondyle, grt greater tubercle, hh humeral head, int internal tuberosity, lco lateral condyle, mco medial condyle.", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271276-25-peerj-10-12727-g019.jpg" }
008962
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Manual phalanges of Eotyrannus lengi IWCMS: 1997.550.The directional terms used here imagine the manus with its extensor surface oriented dorsally. (A) Possible left manual phalanx I-1 in medial view; (B) dorsal view; (C) distal view; (D) lateral view; (E) ventral view; (F) proximal view; (G) possible right phalanx II-1 in lateral view; (H) dorsal view; (I) proximal end in oblique view; (J) medial view; (K) ventral view; (L) proximal view; (M) possible right manual phalanx II-2 in medial view (the incomplete shaft of what is probably metacarpal III adheres to it surface); (N) lateral view; (O) oblique proximal view; (P) diagrammatic representation of possible right manual phalanx II-2 in medial view; (Q) diagrammatic representation of possible right manual phalanx II-2 in lateral view; (R) partial proximal end of left manual phalanx II-2 in lateral view; (S) view; (T) proximal view; (U) medial view; (V) ventral view; (W) proximal view; (X) left or right possible manual phalanx III-2 in lateral or medial view; (Y) dorsal view, distal end to left; (Z) oblique anterodorsal view; (A′) lateral or medial view (opposite side to that shown in (X)); (B′) ventral view; (C′) proximal view; (D′) possible left manual phalanx III-3 in medial view; (E′) dorsal view; (F′) distal view; (G′) lateral view; (H′) ventral view; (I′) proximal view; (J′) impression of ventral surface of unidentified manual phalanx as preserved on matrix, distal end to left; (K′) incomplete distal end of unidentified manual phalanx consisting only of articular condyles ad part of shaft in distal view; (L′) dorsal or ventral view, distal end toward top of page; (M′) dorsal or ventral view (though showing opposite surface to that shown in (L′)), distal end toward bottom of page; (N′) oblique distolateral view of possible right phalanx II-1 (also shown in (G)–(L)); (O′) possible left manual phalanx I-1 shown in articulation with left metacarpal I; (P′) metacarpals and phalanges arranged to show probable positions within the manus. Several phalanges are unknown (III-2, III-4).", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271276-34-peerj-10-12727-g023.jpg" }
008963
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Manual unguals of Eotyrannus lengi IWCMS: 1997.550.(A) Possible pollex ungual in lateral or medial view; (B) same element from opposite side; (C) ventral view; (D) dorsal view; (E) possible digit II ungual in ventral view; (F) lateral or medial view; (G) same element from opposite side; (H) proximal view; (I) oblique dorsoproximal view of proximal end of possible digit II ungual from same side as shown in (F); (J) ventral view. clgr claw groove, dcon dorsoproximal concavity, dli dorsal lip, dol dorsal lamina, flt flexor tubercle.", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271276-35-peerj-10-12727-g024.jpg" }
008964
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Left coracoid of Eotyrannus lengi IWCMS: 1997.550.(A) Coracoid in anterior view; (B) oblique posteroventral view; (C) posterior view; (D) lateral view, anterior to the left; (E) posterior view; (F) medial view, anterior to the right; (G) oblique dorsomedial view to show concave medial surface; (H) ventral view. cortu coracoid tubercle, doc dorsal concavity, epm embayed posterior margin, glef glenoid fossa, mec medial concavity, pvp posteroventral process.", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271276-36-peerj-10-12727-g018.jpg" }
008965
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Incomplete left and right dentaries of Eotyrannus lengi IWCMS: 1997.550.(A) Left dentary in lateral view; (B) left dentary in lateral view with lateral furrows emphasised; (C) left dentary in oblique dorsomedial view; (D) left dentary in medial view; (E) left dentary in dorsal view; (F) oblique dorsolateral view of anterior end of left dentary; (G) anterior end of right dentary in lateral view; (H) anterior end of right dentary in medial view, rotated such that laterally deflected tip is better visible in medial view; (I) right dentary in medial view (laterally deflected tip thus directed away from viewer and partly obscured); (J) right dentary in medial view with most obvious interdental plates emphasised; (K) right dentary in dorsal view; (L) right dentary in ventral view. intpl interdental plates, latf lateral furrows, mg Meckelian groove, nefo neurovascular foramina, rosno rostral notch, sg secondary groove.", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271276-37-peerj-10-12727-g011.jpg" }
008966
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "The more informative of the several rib fragments known for Eotyrannus lengi IWCMS: 1997.550.(A) Dorsal rib segment in oblique view to show cross-sectional shape of capitulum; (B) same dorsal rib segment but in presumed anterior view; (C) dorsal rib segment in presumed anterior view, showing pneumatic recess; (C) and (D) partial rib shaft with flange-like lateral extension, shown in anterior and posterior views. cap capitulum, cog costal groove, intr intercostal ridge, pnre pneumatic recess, tub tuberculum.", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271276-38-peerj-10-12727-g016.jpg" }
008967
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Palatines and possible vomers of Eotyrannus lengi IWCMS: 1997.550.(A) Left palatine as preserved on block of matrix in lateral view, anterior to the left. (B) Left palatine digitally removed from matrix. (C) Incomplete fragment of anterior end of right palatine and possible posterior ends of vomers, as preserved on block of matrix in lateral view. bofr bone fragment, cho border of choana, juar jugal articulation, juar jugal articulation, maxa maxillary articulation, ppr palatine pneumatic recess, ptpr pterygoid process, sr sinuous ridge, vo vomer, vproc vomeropterygoid process.", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271276-40-peerj-10-12727-g009.jpg" }
008968
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Metatarsals of Eotyrannus lengi IWCMS: 1997.550.(A) Distal end of left metatarsal III in anterior view; (B) medial view; (C) lateral view; (D) posterior view; (E) distal view; (F) proximal end of left metatarsal IV in oblique medial view; (G) lateral view; (H) medial view; (I) proximal view, posterior surface toward top of page; (J) distal end of left metatarsal IV in posterior view; (K) known metatarsal elements of E. lengi arranged in approximate in-life configuration to mimic appearance of a left metatarsus, though with right metatarsal II flipped to appear like a left and metatarsal IV shown in posterior aspect as the anterior surface is not available. extfo extensor fossa, latc lateral condyle, medc medial condyle, mtfIII facet for mt III.", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271276-9-peerj-10-12727-g029.jpg" }
008969
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Upregulation of mmu_circ_0015268 promoted endothelial dysfunction in vivo and in vitro. (A) Representative blot results showing the levels of BAX, BCL2, Caspase3, cleaved PARP1, E-selectin, ICAM1, VCAM1, P120-catenin, β-catenin, and E-cadherin in lung tissues. (B) PMLECs were transfected with mmu_circ_0015268 overexpressing vector (OV) or mmu_circ_0015268 shRNA (shRNA), followed by LPS stimulation. Representative blot results showing the levels of BAX, BCL2, Caspase3, cleaved PARP1, E-selectin, intercellular cell adhesion molecule-1 (ICAM1), vascular cell adhesion protein 1 (VCAM1), P120-catenin, β-catenin, and E-cadherin in PMLECs. (C, D) Immunofluorescence intensities of ICAM1 and VCAM1 in vivo and in vitro for different groups.", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271288-0-aging-14-204125-g004.jpg" }
008970
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Expression of mmu_circ_0015268 in LPS-stimulated lung tissues and PMVECs. ALI model was evaluated by histological analysis (A, B), hepatic-injury marker (ALT activity) (C) and renal injury marker (creatinine concentration) (D). (E) Expression of mmu_circ_0015268 in whole lungs after LPS treatment. (F) Expression of mmu_circ_0015268 in primary lung microvascular endothelial cells (PMLECs) stimulated with LPS. **P < 0.01.", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271288-2-aging-14-204125-g002.jpg" }
008971
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "The effect of Huangqi Guizhi Wuwu Decoction on the morphology of nerve cells of L4-L5 dorsal root ganglions of different rat groups. (A–E) A group- E group.", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271291-4-aging-14-203794-g005.jpg" }
008972
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Neural switch costs differ by comorbidity status. Left: Significant group effects on neural switch costs were found in both time bins of high gamma, including the left cerebellum, left inferior (not shown) and superior frontal regions and the right parietal cortex in the early high gamma window, and left precentral, left occipital, left cerebellum, and right parieto-occipital regions in late high gamma activity. Right: Greater neural switch costs in early bin parietal alpha activity were found in type 2 diabetes patients with additional comorbidities, relative to those without comorbidities. These effects show the impact of comorbidities on neural switch costs across the spectrum. Images are thresholded from p < 0.01 to p < 0.001, with a minimum cluster size of 20 4 mm3 voxels.", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271300-3-aging-14-204129-g003.jpg" }
008973
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Depletion of SNX20 inhibits GBM cell proliferation and migration. (A) The expression of SNX20 in normal human astrocytes cells (NHA) and GBM cell lines (U87, A172 and U251). (B) The SNX20 knockdown efficiency in A172 and U87 cells were verified by qRT-PCR assay. (C–E) SNX20 knockdown significantly inhibited A172 and U87 cells proliferation examined by growth curve and colony formation assays. (F) SNX20 knockdown significantly inhibited A172 and U87 cells migration examined by transwell assay. Scale bar=50 μm. NC=Negative control, siRNA= SNX20 siRNA, * P < 0.05, ** P < 0.01, *** P < 0.001.", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271302-0-aging-14-204144-g010.jpg" }
008974
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "TXNIP mediated galectin-3-induced ROS and inflammation factors expression in VSMCs. VSMCs were treated with 10 μg/ml galectin-3 and (or) TXNIP siRNA for 24 h, The protein expression level of NLRP3, caspase-1, and IL-1β were measured by western blot, the results quantifications were shown in the right panel (A and B). Band density of native VSMCs was defined as a control and considered to 1. DHE staining was used to observe the ROS production (C). Data were obtained from three independent experiments. *P < 0.05, vs. the control; #P < 0.05 vs. galectin-3.", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271303-4-aging-14-204130-g003.jpg" }
008975
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Exploration of the 6 IRIGs as predictive diagnostic indicators based on the TCGA-COAD cohort. (A) Comparison of the expressions of the IRIGs between tumor and normal samples using the Wilcoxon test. (B) Establishment of the predictive diagnosis model using the 6 IRIGs. (C–F) The comparison of protein expression of NRG1 and CRLF1 between tumor and normal tissues.", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271306-4-aging-14-204134-g006.jpg" }
008976
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "PEG11as silencing inhibited neuronal autophagy and apoptosis. (A) A FISH assay showed the location of PEG11as in mouse primary neurons. Green, PEG11as; Blue, DAPI. (B) Transmission electron microscopy was applied to observe the ultrastructural features in hippocampal of tMCAO/R mice. Blue arrow indicated autophagosomes and yellow arrow represented lysosomes. (C, D) Representative double immunofluorescent staining for NeuN and MAP1LC3B (C) and SQSTM1/p62 (D) in ischemic hemispheres transfected with shRNA-PEG11as 14 days and treated with tMCAO/R. (E) Representative pictures and statistical chart for the western blot of MAP1LC3 staining. n = 3. One-way ANOVA followed by the Tukey’s post-hoc-test was used, data are statistically different from each other with *P < 0.05, **P < 0.01 and ***P < 0.001. Abbreviation: ns: no statistically different vs. IS/R group.", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271312-2-aging-14-204140-g003.jpg" }
008977
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "CTA heada: Portions of the right temporal findings appeared very well circumscribed on the CTA head with a possible thin enhancing rim (arrow). b: In other portions, you can see where hemorrhage (arrowhead) has extended beyond the faintly enhancing rim (arrow)CTA: computed tomography angiography", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271313-0-cureus-0014-00000025823-i02.jpg" }
008978
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "MRI brain without and with contrasta and b: T2 and FLAIR sequences demonstrating a lesion with a T2 hypointense rim (arrows) with surrounding edema. Internal fluid-fluid levels likely related to the internal hemorrhagic component. Additional regions of hemorrhage with fluid-fluid levels (arrowheads) are seen outside of the T2 hypointense rim. c: SWI sequence demonstrating marked susceptibility artifact representative of the hemorrhage, which appears to coincide with the regions that exhibit fluid-fluid levels. d and e: T1 precontrast and postcontrast imaging demonstrate an enhancing component of tumor (arrowhead) along the lateral margin. f: Zoomed-in coronal T1 postcontrast demonstrating enhancing component of the tumor along the lateral margin with the additional suggestion of thin peripheral enhancement (arrows)MRI: magnetic resonance imaging; FLAIR: fluid-attenuated inversion recovery; SWI: susceptibility-weighted imaging", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271313-1-cureus-0014-00000025823-i03.jpg" }
008979
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "CT head without contrasta: Large right temporal intraparenchymal hemorrhage (arrow) with surrounding edema as well as partially visualized subdural hemorrhages along the anterior falx and bilateral tentorium. b: Subdural hemorrhage along the falx (arrowhead) and bilateral cerebral convexitiesCT: computed tomography", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271313-2-cureus-0014-00000025823-i01.jpg" }
008980
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Oblique spiral midshaft diaphyseal fracture of the left tibia with (a) AP and (b) lateral views", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271314-0-cureus-0014-00000025822-i01.jpg" }
008981
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Scoliosis study denoting dextroscoliosis of the thoracic spine, kyphoscoliosis, and compression deformities at the T7-T9 levels with (a) PA and (b) lateral views", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271314-1-cureus-0014-00000025822-i05.jpg" }
008982
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Right oblique tibial fracture with (a) AP and (b) lateral views", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271314-2-cureus-0014-00000025822-i02.jpg" }
008983
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Right forearm fracture with (a) AP, (b) oblique, and (c) lateral views", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271314-3-cureus-0014-00000025822-i03.jpg" }
008984
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "CT (coronal plane) of the thyroid gland with extension into the mediastinum.Yellow arrow indicates dilated right proximal external and internal jugular vein, orange arrow indicates dilated left internal carotid artery, red arrow indicates displaced trachea to right secondary to mass effect of goiter, purple arrow indicates cystic part of the goiter in the mediastinum compressing the heart, and green arrow indicates the compressed heart with clear plane between the pericardium and goiter.", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271320-0-cureus-0014-00000025827-i01.jpg" }
008985
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "CT (sagittal plane) of the goiter extending below thoracic inlet into mediastinum.Yellow arrow indicates solid cystic component of goiter at the cervical region, green arrow indicates goiter extending below thoracic inlet, upper border of the manubrium (front) to upper border body of first thoracic (behind), red arrow indicates arch of the aorta, with the goiter extending below the arch of the aorta, blue arrow indicates the compressed superior vena cava, and orange arrow indicates goiter’s inferior border extending till T9 vertebra.", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271320-2-cureus-0014-00000025827-i02.jpg" }
008986
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Intraoperative view of the goiter after sternotomy.", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271320-3-cureus-0014-00000025827-i03.jpg" }
008987
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Resected goiter.", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271320-4-cureus-0014-00000025827-i04.jpg" }
008988
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "A: Implant bed. B. Inserting the silicone tube that is connected to a controlled internal maxillary sinus elevation device in the prepared implant bed until it reached the membrane of the maxillary sinus, and sealing it using the flowable composite", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271324-1-cureus-0014-00000026711-i06.jpg" }
008989
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "The evaluation and measurement of elevation height (mm) of the maxillary sinus membrane by using a special tool", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271324-3-cureus-0014-00000026711-i10.jpg" }
008990
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Membrane elevation using the controlled internal maxillary sinus elevation device (CIMSED), and monitoring the sinus membrane through the exposed medial wall of the maxillary sinusA: Applying the initial pressure. B: Membrane elevation observation. C: Increasing the applied pressure. D: Resulting membrane elevation", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271324-5-cureus-0014-00000026711-i07.jpg" }
008991
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Visual inspection of perforations", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271324-6-cureus-0014-00000026711-i11.jpg" }
008992
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "A: The CBCT scan using Picasso® Pro CBCT system. B: The determination of the appropriate location of elevationCBCT: cone-beam computed tomography", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271324-7-cureus-0014-00000026711-i03.jpg" }
008993
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "A: The sheep's half head (lateral view). B: Dissecting the nasal mucosa. C: After removing the lower and middle nasal concha. D: Preparing the monitoring window", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271324-8-cureus-0014-00000026711-i04.jpg" }
008994
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "A: The 2.2-mm twisted drill. B: The 3.1-mm drill. C and D: Examining the integrity of the maxillary sinus membrane and the bone height using the depth gauge provided by the Crestal Approach Sinus kit (Osstem Implant Co)", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271324-9-cureus-0014-00000026711-i05.jpg" }
008995
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "A: Canal not subjected to orthograde treatment (circle) in an upper lateral incisor; B: Canal not subjected to orthograde treatment (circle) in an upper central incisor. Note the presence of opaque dentin (star); C: Joining isthmus between two canals (arrow) in the mesial root of a lower first molar. Zones of opaque dentin are also seen (star).", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271341-0-medoral-27-e375-g002.jpg" }
008996
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "A: Craze line (arrow) in an upper canine; B: Craze line (arrow) in the distal root of an upper first molar; C: Crack lines (arrow) in the mesial root of a lower first molar. Note the presence of opaque dentin (star); D: Crack lines (arrow) in the distal root of an upper first molar. Opaque dentin is also observed (star).", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271341-3-medoral-27-e375-g003.jpg" }
008997
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "A: Gap between the filler material and dentin wall in the buccal root of an upper first premolar; B: Gap between the filler material and dentin wall in the distal root of an upper first molar.", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_46-PMC9271341-4-medoral-27-e375-g004.jpg" }
008998
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar
{ "caption": "Reflecting measurements performed in mandible. a) Measurement of the cortical bone thickness bilaterally; b) Measurement of the distance between the upper border of foramen mentale and inferior border of mandible; c) Measurement of the distance between the lower border of foramen mentale and inferior border of mandible; d) Measurement of the alveoler crest height; e-f) Measurement of the length of mandible.", "subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_47-PMC9271343-1-medoral-27-e357-g001.jpg" }
008999
hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar