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54,571,126 | {
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"DOI": "10.5194/SOIL-1-65-2015",
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} | Abstract. In the present paper we explore to what degree soil properties might have influenced pre-Columbian settlement patterns in the Monumental Mounds Region (MMR) of the Llanos de Moxos (LM), Bolivian Amazon. Monumental mounds are pre-Hispanic earth buildings and were preferentially built on mid- to late Holocene palaeolevees of the Grande River (here denominated PR1), while levees of older palaeorivers (PR0) were only sparsely occupied. We dug two transects across PR0 and PR1 levee–backswamp catenas and analysed them for grain size, pH, cation exchange capacity (CEC) and Corg. Our data show that PR1 soils, where the density of mounds is higher, have far greater agricultural potential than PR0 soils, which are affected by aluminium toxicity in the backswamps and by high levels of exchangeable sodium in the levees. This study provides new data on the soil properties of the south-eastern Bolivian Amazon and reinforces the hypothesis that environmental constraints and opportunities exerted an important role on pre-Columbian occupation patterns and the population density reached in the Bolivian Amazon. | 2022-12-25T23:35:24.221Z |
37,875,533 | {
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"DOI": "10.1111/j.1540-8159.1994.tb03747.x",
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} | Submaminary pacemaker implantation offers women a cosmetically acceptable alternative to the standard pectoral implant. We present a novel method of submammary implantation performed on ten women aged 13–54 years. The lead electrodes are tunneled from the infraclavicular to the inframammary incision using a long needle, guidewire, and introducers/dilators in a manner analogous to the retained guidewire technique used for standard lead insertion. The procedure can generally be performed under local anesthesia. All patients tolerated the procedure well without acute complications. Over 2‐ to 23‐month follow‐up, there were no lead dislodgments. No patients developed mastitis or incisional complications, and all have been extremely satisfied with the cosmetic results. With proper technique, submammary pacemaker implantation can be performed under local anesthesia with minimal patient discomfort and optimal cosmesis. | 2022-07-26T07:25:31.764Z |
105,483,418 | {
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"DOI": "10.1080/00223131.2018.1532846",
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} | ABSTRACT Seismic design of nuclear power plants (NPPs) is important for ensuring their integrity during earthquakes. Seismic analysis has been conducted using lumped mass beam models (LMBMs) for the design of plants in Japan, whereas three-dimensional (3D) finite element models (FEMs) have been used for novel plants outside Japan. The purposes of this study are to organize issues related to the development and application of 3D FEMs for seismic analysis of Japanese NPPs and to indicate future study directions. To organize these issues, the authors systematically investigated: (1) international guides and standards related to seismic analysis and (2) 3D FEMs of novel NPPs outside Japan. By considering other studies on the issues, the authors suggest directions for future studies. Resolving the issues will contribute to application of 3D FEMs for seismic analysis in the design of Japanese NPPs. | 2022-09-10T17:52:27.943Z |
7,237,142 | {
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"ArXiv": null,
"DOI": "10.1177/0886260514563836",
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} | Neglect poses a significant risk for children throughout their development and is often linked with serious consequences that reach into adulthood. The Child Neglect Questionnaire (CNQ) fills existing gaps by incorporating multiple perspectives from both parents and the child, as well as measuring the complex phenomenon of neglect multidimensionally. Furthermore, this measure addresses the need for an instrument specifically developed for late childhood (ages 10-12), as much of the extant evidence and corresponding measures focus on young children and their mothers. A panel of three psychologists, using Cicchetti’s model of child neglect as a theoretical guide, began by selecting items from an existing database. Results of exploratory and confirmatory factor analyses and item response theory demonstrated the unidimensionality of physical, emotional, educational, and supervision neglect as well as a second-order construct of child neglect. Analyses controlling for risk status due to father’s substance use disorder, socioeconomic status, and child’s ethnicity demonstrated that father’s and mother’s (parental) neglect, particularly in the child’s versions, had sound concurrent and predictive validity. Concurrently, at age 10-12, the child’s version of both parents’ neglect correlated with their parenting behaviors evaluated by other available measures. Prospectively, from 10-12 years of age to 11-13 years of age, parental neglect predicted child’s drug use frequency with coexisting psychological dysregulation, psychiatric symptoms, antisocial behavior, non-normative sexual behavior, involvement with deviant peers and leisure activities thus demonstrating sound predictive validity. Also, internal consistency and inter-rater reliability were excellent. The CNQ, particularly the child’s version, may thus be useful for detecting children at high risk for parental neglect. | 2022-10-22T20:30:55.274Z |
21,314,295 | {
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"DOI": "10.1111/j.1365-4362.1989.tb02446.x",
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} | Morphea-like basal cell epithelioma Is a rare type of skin cancer. Experienced dermatologists see few in a long clinical career. By the time one is seen and diagnosed, it invariably has been present several years. AI that time the classic picture, a yellow-whitish, bound down, firm to the touch, scarlike lesion without a clinically appreciable border, is evident. From its first mention in the literature in 1895' descriptiotis given are of this mature classic lesion. I recently saw a woman with a light tan complexion who had such a lesion. Histopathologic examination of biopsied tissue revealed nests and cords of basaloid cells with hyperchromatism and peripheral palisading of the nuclei surrounded by a dense fibrous stroma. Three years earlier, however, she had a sharply bordered, markedly hypopigmented patch that was soft to the touch and was not bound down or scar-like. At that time it had been present several months and was diagnosed as vitiligo. In recent years interest in this type of skin cancer has been limited to discussions of the most appropriate method of removal. I decided to review the literature further to see if the evolutionary change my patient showed had been previously reported. The closest that I could find was a tnention that in 1898 a case had been presented at the Third International Congress of Dermatology (London) in wbich morphea-like basal cell epithelioma began as a "small white spot."^ This report should alert dermatologists as to how this rare skin cancer may look as it begins to evolve. It may be that a subtle early sign of morphea-like basal cell carcinoma Is simply a loss of pigmentation. How discernible this would be would depends on the person's complexion. Once aware of this possibility the dermatologist's suspicion should be increased if only a single patch of "vitiligo" is present. I believe that this information may facilitate earlier diagnosis in the future and that will make removal less difficult. | 2022-12-15T02:06:38.745Z |
28,280,916 | {
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"DOI": "10.2175/106143015X14362865225951",
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} | This study investigated the contribution of hydrogen sulfide to biological oxygen demand (BOD5) and chemical oxygen demand (COD) in wastewater effluents, and documented the effect of storage times and conditions on the BOD5 and COD of pH‐adjusted sodium sulfide solutions as well as graywater wetland effluent. Initial COD measurements of sulfide solutions were 84‐89% of the theoretical oxygen demand (ThOD), 1.996 mg O2/mg S, whereas unseeded BOD5 measurements were 55‐77%. For sulfide solutions, all storage conditions led to declines of >15% (COD, BOD5), and >31% (sulfide). For wetland effluent, storage without headspace was effective in reducing COD losses (3.7%), compared to storage with headspace (17%), and affected changes in turbidity, UVA‐254 and pH. The results suggest that storage times and conditions should be controlled and reported when reporting BOD5 and COD of sulfide‐rich samples. Wetland models representing sulfate reduction as a method of COD removal may need to be reconsidered. | 2022-12-16T23:13:40.388Z |
55,425,850 | {
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"DOI": "10.1051/AAS:1999420",
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} | This paper consists of two parts. In the rst one, we make a comparative analysis of the algo- rithms of Richardson-Lucy (RLA) and the Image Space Reconstruction Algorithm (ISRA), for image deconvolu- tion of astronomical images. These iterative algorithms keep the reconstructed image non-negative while max- imizing the likelihood for a Poisson Process (RLA) or a Gaussian process (ISRA). Their comparison is made easier when these algorithms are rewritten as descent algorithms; the additive forms evidence the role of the variances of the noise and allow a better understanding of these algorithms. A numerical illustration is performed from simulated images. In practice, the results obtained by the two algorithms appeared to be very similar, independently of the statistics of the noise. In the second part of the paper, we propose a new objective-stopping technique that makes use of a com- parison of the results of these algorithms with that of the Wiener lter. The comparison is made in the Fourier plane, computing the Euclidean distances between mod- ules of the spatial frequencies components of the images. We propose then to use the results of ISRA and RLA at the iteration number corresponding to the minimum of that distance. The technique is checked in a numerical simulation, for which the optimal iteration numbers can be easily determined. A good agreement is obtained between best ISRA and RLA results and the Wiener lter, in particular for rather noisy images. However ISRA and RLA produce very high frequency components, outside the cut-o frequency of the instrument; limiting the iteration number alone cannot al- low a perfect agreement with the Wiener approach, stress- ing the need of an explicit regularization for astronomical applications. | 2022-12-19T07:03:28.535Z |
170,190,560 | {
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"DOI": "10.1111/J.1933-1592.2007.00091.X",
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} | In this paper, I examine the crucial relationship between Locke’s theory of individuation and his theory of kinds. Locke holds that two material objects—e.g., a mass of matter and an oak tree—can be in the same place at the same time, provided that they are ‘of different kinds’. According to Locke, kinds are nominal essences, that is, general abstract ideas based on objective similarities between particular individuals. I argue that Locke’s view on coinciding material objects is incompatible with his view on kinds. In order for two material objects to be in the same place at the same time, they must differ with respect to at least one nominal essence. However, Locke thinks that it is impossible that x and y have the same real essence but differ with respect to any nominal essence; and coinciding material objects have the same real essence. Therefore, Locke cannot hold what he in fact holds, namely that distinct material objects can be in the same place at the same time. | 2022-12-23T01:58:10.286Z |
21,463,623 | {
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"DOI": "10.1073/pnas.0800708105",
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"status": "GREEN",
"url": "https://europepmc.org/articles/pmc2359796?pdf=render"
} | The peptide hormone ghrelin is the only known protein modified with an O-linked octanoyl side group, which occurs on its third serine residue. This modification is crucial for ghrelin's physiological effects including regulation of feeding, adiposity, and insulin secretion. Despite the crucial role for octanoylation in the physiology of ghrelin, the lipid transferase that mediates this novel modification has remained unknown. Here we report the identification and characterization of human GOAT, the ghrelin O-acyl transferase. GOAT is a conserved orphan membrane-bound O-acyl transferase (MBOAT) that specifically octanoylates serine-3 of the ghrelin peptide. Transcripts for both GOAT and ghrelin occur predominantly in stomach and pancreas. GOAT is conserved across vertebrates, and genetic disruption of the GOAT gene in mice leads to complete absence of acylated ghrelin in circulation. The occurrence of ghrelin and GOAT in stomach and pancreas tissues demonstrates the relevance of GOAT in the acylation of ghrelin and further implicates acylated ghrelin in pancreatic function. | 2022-12-24T14:39:39.630Z |
147,319,493 | {
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"DOI": "10.18060/18590",
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"status": "GOLD",
"url": "https://journals.iupui.edu/index.php/advancesinsocialwork/article/download/18590/20467"
} | Modern advances in neuroscience suggest learning occurs through three basic cognition patterns. Higher-level multimodal learning occurs when learning activities contain multiple cognition patterns. This case study details an application of these concepts where fine art, journaling, practicum experiences, and in-class processing were fused to create an active and participatory method of engaging social work students in critical thinking as related to differential impacts of clinical decision-making. The learning activities are described and multimodal learning is explained, along with the findings of a focus group used to assess student feedback. Student experiences and the potential adaptations of this approach are also addressed. The tentative findings of this case study indicate positive learning experiences and suggest a need for further research to explore the opportunities associated with the use of multimodal and art-infused learning techniques in social work courses. | 2022-08-21T02:06:51.974Z |
7,029,607 | {
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"DOI": "10.1145/2503778.2503786",
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} | Haskell's type system has outgrown its Hindley-Milner roots to the extent that it now stretches to the basics of dependently typed programming. In this paper, we collate and classify techniques for programming with dependent types in Haskell, and contribute some new ones. In particular, through extended examples---merge-sort and rectangular tilings---we show how to exploit Haskell's constraint solver as a theorem prover, delivering code which, as Agda programmers, we envy. We explore the compromises involved in simulating variations on the theme of the dependent function space in an attempt to help programmers put dependent types to work, and to inform the evolving language design both of Haskell and of dependently typed languages more broadly. | 2022-09-15T14:53:22.172Z |
252,232,628 | {
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"DOI": "10.1039/d2an01393b",
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} | Herein, we report a portable point-of-care testing (POCT) device based on an aptamer-engineered extended-gate field-effect transistor (EG-FET) for therapeutic monitoring of the drug methotrexate. This method was shown to be highly sensitive, efficient, and convenient to use, features contributing to its realizing a clinical detection of drugs in blood. | 2022-09-24T07:13:46.204Z |
30,564,745 | {
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"DOI": "10.1136/bmj.1.5338.1132",
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"url": "https://europepmc.org/articles/pmc2123047?pdf=render"
} | RTemvl.ofa consider let ppretin of then excss uric acid from the patient by haemodialysis might be expected to result in a t mp rary improve en in renal function. Presumably this is the explanation of the return of normal urine output and sustained fall in plasma urea level after the second dialysis, since there was no evidence of haematological improvement at this Stage. The longer and more complete return of renal function after the first dialysis was probably due in part to a remission in the underlying reticulosis, for during the dialysis and following his liver biopsy and laparotomy he received a total of 5 litres of blood. A temporary remission of acute leukaemia is known to occur in about 30% of adults treated by blood transfusion alone (Hayhoe and Whitby, 1955), and during such a remission there is a striking fall in uric-acid output (Dickinson, 1960). As with our patient, the response to a second transfusion is usually less complete. | 2022-12-10T08:52:52.480Z |
197,413 | {
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"DOI": "10.1111/J.1462-2920.2007.01411.X",
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} | How to explore protein sequence space efficiently and how to generate high-quality mutant libraries that allow to identify improved variants with current screening technologies are key questions for any directed protein evolution experiment. High-quality mutant libraries can be generated through improved random mutagenesis methodologies and by restricting diversity generation through computational methods to residues which have high success probabilities. Advances in mutant library design and computational tools to focus diversity generation are summarized in this minireview and discussed from an experimentalist point of view in the context of directed protein evolution. | 2022-12-15T07:11:01.451Z |
22,875,732 | {
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"DOI": "10.1109/PPIC.2016.7523481",
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} | The application of speed control using adjustable speed drives (ASDs) in industrial applications that contain fans and pumps enables improved energy efficiency and conservation and offers improved process control. However, the success of the application in terms of energy conservation and improved process control depends upon tempering enthusiasm with disciplined logic in order to maximize the benefits. This can only be done by understanding the requirements of the process, understanding the use of the ASD within the process, and understanding the potential for both risk and success for the outcome. Use of speed control does not necessarily equate to energy savings and improved process control. It is only the judicious application of speed control that provides a successful outcome. This paper will consider proven methodologies that may be used in selecting suitable applications for ASDs. | 2022-12-17T06:47:25.196Z |
149,184,812 | {
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"DOI": "10.1017/9781108303668",
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} | The philosophy of perception has been an important topic throughout history, appealing to thinkers in antiquity and the middle ages as well as to figures such as Kant, Bergson and others. In this wide-ranging study, Mark Eli Kalderon presents multiple perspectives on the general nature of perception, discussing touch and hearing as well as vision. He draws on the rich history of the subject and shows how analytic and continental approaches to it are connected, providing readers with insights from both traditions and arguing for new orientations when thinking about the presentation of perception. His discussion addresses issues including tactile metaphors, sympathy in relation to the concept of fellow-feeling, and the Wave Theory of sound. His comprehensive and thoughtful study presents bold and systematic investigations into current theory, informed by centuries of philosophical enquiry, and will be important for those working on ontological and metaphysical aspects of perception and feeling.
Read more at http://www.cambridge.org/gb/academic/subjects/philosophy/epistemology-and-metaphysics/sympathy-perception#IJSqEsPDSc346Otf.99 | 2022-12-25T21:46:23.224Z |
194,097,858 | {
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"ArXiv": null,
"DOI": "10.3917/AGORA.048.0090",
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} | Cet article repose sur une enquete socio-ethnographique effectuee dans une cite du sud de Paris. Il s’interesse aux enfants, mais surtout aux adolescents et aux jeunes adultes qui utilisent les rues de leur cite davantage comme un lieu de vie que comme un lieu de passage, et qui forment des « bandes » plus ou moins structurees par des activites delinquantes, et en particulier par le trafic de stupefiants, l’activite la plus rentable. Il eclaire ensuite la structuration de cette activite par l’accumulation, entre les annees 1980 et aujourd’hui, de competences techniques, relationnelles et economiques. | 2022-02-08T08:17:24.749Z |
14,758,251 | {
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"DOI": "10.1002/dta.1554",
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} | Drug facilitated crimes (DFCs) can be defined as criminal acts carried out by means of administering a substance to a person with the intention of impairing behaviour, perceptions, or decision-making capacity. It also extends to taking advantage of an impaired person after voluntary intake of an incapacitating substance. Crimes include robbery, money extortion, and maltreatment of the elderly, children, or mentally ill patients. Rape or other types of sexual assault are referred to as drug facilitated sexual assault (DFSA). In DFSA cases, the victim is subjected to a sexual act without legal consent as a result of the pharmacological effects of alcohol and/or drug(s). A large number of psychoactive substances have the potential to alter the victim’s state of mind, alcohol being the number one candidate because of its widespread use. Illicit drugs, psychoactive prescription drugs and even over-the-counter medicines are also likely candidates, either consumed alone or in combination with alcohol. The resulting pharmacological effects may include relaxation, euphoria, and lack of inhibition on the one hand and drowsiness, loss of motor function, unconsciousness, and amnesia on the other hand. Information on the frequency of DFC cases is scarce but there has been a significant increase in reports worldwide. However, several factors complicate the registration of the actual number of DFSA cases. Governmental statistics show a general underreporting of sexual assault crimes. The impact that central nervous system depressant drugs have on memory and consciousness might lead to a situation where the victim is not able to remember what has actually happened and chooses not to report the incident. If the incident is reported, police officers often assume that the victim was simply drunk rather than drugged. If an investigation is initiated, the delay between the collection of biological evidence and the alleged assault can be between several hours and more than a day. This case report describes a DFSA case in a medical setting: a gynaecologist was suspected of assaulting a young patient after drug administration. In the presented case, the time delay between the alleged assault and the sampling was 30 h. Evidence collection via a standardized sampling kit and the choice of sample in such cases is discussed. The analytical strategy is described with regard to the choice of methods, uncertainty measurement, and limitations of the methods which are important during interpretation of the analytical results. Finally, interpretation of this specific case, but also interpretation issues of DFSA cases in general, is discussed. | 2022-02-13T02:26:29.232Z |
26,751,369 | {
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"ArXiv": null,
"DOI": "10.1109/RAST.2007.4284101",
"MAG": "2050708293",
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} | European Space Agency (ESA), the World over Scientific organization, North Atlantic Treaty Organization (NATO), National Aeronautics and Space Administration (NASA) and WOrld Meteorological Organization are deeply concerned with the dis-balances caused to a significant extent due to human interference in the natural make-up of earth's ecosystem. In particular, the ozone layer depletion (OLD) over the South Pole is already a serious hazard. The principal long-term effect of OLD appears to be an increase in the UV radiation reaching the earth. In our earlier findings on OLD have been reported and the effects could be observed using the data obtained from a ground based instrument known as Dobson Spectrophotometer installed at GC Quetta Pakistan. We have also computed UV flux reaching Arabian Sea due to the OLD. Then we have presented correlation structures of the population dynamics of marine organisms (fish yield and others) with the intensity of UV flux. The results are compared with the data acquired from Total Ozone Mapping Spectrometer (TOMS) Nimbus -7. | 2022-03-05T15:33:21.704Z |
146,632,553 | {
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"ArXiv": null,
"DOI": "10.1080/01639625.1989.9967799",
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} | This paper reviews the current literature concerning social control in the U.S. Army with special emphasis upon the convergence/divergence debate now guiding much of the legal and sociological conceptualizing in this research. Emphasizing the weaknesses in this literature, a new socio‐legal conceptual model based upon the work of Weber (1921/1978), Rustad (1982), Nonet and Selznick (1978) as well as classical military source material is then proposed as an alternative to the current debate in the literature. | 2022-09-01T03:03:46.053Z |
8,614,194 | {
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"DOI": "10.5301/ejo.5000421",
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} | Purpose Intravitreal aflibercept, a fusion protein with high affinity for vascular endothelial growth factor, offers an alternative treatment for exudative age-related macular degeneration. Preclinical studies and early and late phase clinical trials suggest that aflibercept's high binding affinity may impart greater durability of activity and increased efficacy compared to ranibizumab or bevacizumab. Methods A total of 266 eyes of 249 patients with exudative age-related macular degeneration who received aflibercept after treatment with bevacizumab and/or ranibizumab were included in a retrospective review. Mean central subfoveal thickness on spectral-domain optical coherence tomography and mean logarithm of the minimal angle of resolution (logMAR) visual acuity were calculated at 1, 3, 6, and 12 months after the first aflibercept injection. Subgroup analyses were performed in eyes receiving at least 5 bevacizumab and/or ranibizumab injections in the 6 months prior to aflibercept and in eyes receiving at least 10 injections in the 12 months prior to aflibercept. Results Eyes received an average of 14.7 (range 1–43) ranibizumab and/or bevacizumab treatments prior to initiation of aflibercept therapy. The mean central subfoveal thickness decreased from 300 to 275 μm at 1 month (p<0.001) and was maintained at 6 months. Mean logMAR visual acuity improved from 0.60 (Snellen equivalent 20/80) to 0.54 (20/70, p = 0.01) at 1 month and was stable at 0.55 at 6 months (Snellen equivalent 20/70, p = 0.11, n = 251). In 82 eyes receiving at least 5 injections in the 6 months prior to aflibercept treatment (average of 18.1 injections total), the central subfoveal thickness improved from 296 to 279 μm at 1 month (p<0.0001) and was maintained at 6 months (p<0.0001). Visual acuity did not change (0.48 [20/61] at 1 month compared to baseline, 0.49 [20/62], p = 0.634, and at 6 months 0.51 [20/65], p = 0.601). In 50 eyes receiving at least 10 injections in the 12 months prior to aflibercept treatment (average of 21.8 injections total), the mean central subfoveal thickness decreased by 17 μm at 1 month (p = 0.0007) and was maintained at 6 months (p = 0.013). Again, visual acuity did not change (0.46 [20/56] at 1 month, baseline 0.44 [20/56], p = 0.547, and 0.50 [20/63] at 6 months, p = 0.2445). Conclusions Aflibercept is a valuable treatment alternative in patients previously treated with bevacizumab and/or ranibizumab injections. Stability of visual acuity and anatomic improvement on spectral-domain optical coherence tomography were observed after initiation of aflibercept treatment in those previously treated with ranibizumab and/or bevacizumab injections every 4–6 weeks. | 2022-09-09T14:47:58.241Z |
128,907,471 | {
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"DOI": "10.1002/ESP.3290090408",
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} | Mineralogical study of samples from depression fills on an isolated basalt plateau in Central Sardinia showed that, although the basalt is free of quartz and mica, fair amounts of these minerals occur in the finer fractions. Results from X-ray analyses of silt fractions and morphoscopical analyses of sand fractions indicate that the bulk of the quartz and mica is of eolian origin.
The eolian quartz is predominantly of medium and coarse silt size and, in the upper 10 cm of the depression fills, constitutes about 20 per cent of the soil mass (approx. 20 kg/m2). Eolian mica is present in smaller amounts and is of medium silt or smaller size.
The provenance of the eolian material could not be established with certainty, although a local origin can be excluded. | 2022-09-13T05:45:31.984Z |
22,888,166 | {
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"status": "BRONZE",
"url": "https://journals.lww.com/jaids/Abstract/2000/07010/Interaction_of_Methadone_with_Didanosine_and.7.aspx"
} | We evaluated the prevalence of both Q151M and 6-bp insert at position 69 of RT region responsible for multiple dideoxynucleoside analogue-resistant (MddNR) HIV-1 variants in 177 patients who failed to respond to combination therapy. Patients had received protease inhibitors (PI) and/or nonnucleoside reverse transcriptase inhibitors (NNRTIs) after a long-term experience with nucleoside reverse transcriptase inhibitors (NRTIs) (including zidovudine monotherapy). Two of 177 patients (1.1%) showed the specific complex of Q151M mutation, while 4 (2.3%) had the 69 6-bp insert. Mutations that belong to the 151 set in the absence of the pivotal Q151M substitution were detected in as many as 3.9% of the patients. One patient exhibited a 69S [VG] insert that has not been previously phenotypically characterized. This HIV-1 isolate had high levels of resistance to all NRTIs except stavudine. MddNR is an emerging problem after sequential therapy with this class of compounds among HIV-1-infected patients. Either didanosine (ddI) or zidovudine (ZDV) monotherapy allowed the emergence of MddNR variants containing Q151M complex. Monotherapy with ZDV and ddI or subsequent treatments with various NRTI combinations were the common background in the patients with the 69 insert. The overall prevalence of MddNR (3.4%) in Italy is comparable with that observed in several other European countries (3.4%-6.5%). These data suggest that patients failed by NRTI regimens should be analyzed for the presence of both patterns of MddNR. | 2022-09-15T05:38:17.197Z |
110,545,291 | {
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"DOI": "10.14429/DSJ.47.3994",
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} | It is important to understand the internal ballistic processes for the development of regenerative liquid propellant guns (RLPGs). A 30 mm RLPG test fixture was developed and firing trials were conducted to study the performance of the gun. During the trials, sometimes, combustion ignition in the reservoir took place resulting in substantial damage to the injection piston. This paper highlights the possible causes of this combustion and offers suggestions. regarding improvement in the design. An elaborate instrumentation set-up which could pinpoint the specific conditions leading to failures is suggested. | 2022-02-10T05:02:45.255Z |
244,283,929 | {
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"DOI": "10.3390/foods10112813",
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"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/2304-8158/10/11/2813/pdf?version=1637035951"
} | (1) Background: Protein–polyphenol interactions have been widely studied regarding their influence on the properties of both protein and the ligands. As an important protein material in the food industry, soybean protein isolate (SPI) experiences interesting changes through polyphenols binding. (2) Methods: In this study, a molecular docking and virtual screening method was established to evaluate the SPI–polyphenol interaction. A compound library composed of 33 commonly found food source polyphenols was used in virtual screening. The binding capacity of top-ranking polyphenols (rutin, procyanidin, cyanidin chloride, quercetin) was validated and compared by fluorescence assays. (3) Results: Four out of five top-ranking polyphenols in virtual screening were flavonoids, while phenolic acids exhibit low binding capacity. Hydrogen bonding and hydrophobic interactions were found to be dominant interactions involved in soybean protein–polyphenol binding. Cyanidin chloride exhibited the highest apparent binding constant (Ka), which was followed by quercetin, procyanidin, and rutin. Unlike others, procyanidin addition perturbed a red shift of SPI fluorescence, indicating a slight conformational change of SPI. (4) Conclusions: These results suggest that the pattern of SPI–polyphenol interaction is highly dependent on the detailed structure of polyphenols, which have important implications in uncovering the binding mechanism of SPI–polyphenol interaction. | 2022-12-03T17:35:07.353Z |
124,102,526 | {
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"DOI": "10.1103/PHYSREVLETT.42.622",
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} | The yrast line in $^{22}\mathrm{Ne}$ has been investigated by the reaction $^{11}\mathrm{B}$+$^{13}\mathrm{C}$ up to the ${10}^{+}$ state which is found at 15.46-MeV excitation energy. A backbending in $^{22}\mathrm{Ne}$ shows up around spin 8. The Strutinsky method is applied to interpret the $^{22}\mathrm{Ne}$ rotational motion. | 2022-12-03T05:28:40.928Z |
17,730,340 | {
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"DOI": "10.3389/fpsyg.2013.00706",
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"url": "https://www.frontiersin.org/articles/10.3389/fpsyg.2013.00706/pdf"
} | We present a novel paradigm to identify shared and unique brain regions underlying non-semantic, non-phonological, abstract, audio-visual (AV) memory vs. naming using a longitudinal functional magnetic resonance imaging experiment. Participants were trained to associate novel AV stimulus pairs containing hidden linguistic content. Half of the stimulus pairs were distorted images of animals and sine-wave speech versions of the animal's name. Images and sounds were distorted in such a way as to make their linguistic content easily recognizable only after being made aware of its existence. Memory for the pairings was tested by presenting an AV pair and asking participants to verify if the two stimuli formed a learned pairing. After memory testing, the hidden linguistic content was revealed and participants were tested again on their recollection of the pairings in this linguistically informed state. Once informed, the AV verification task could be performed by naming the picture. There was substantial overlap between the regions involved in recognition of non-linguistic sensory memory and naming, suggesting a strong relation between them. Contrasts between sessions identified left angular gyrus and middle temporal gyrus as key additional players in the naming network. Left inferior frontal regions participated in both naming and non-linguistic AV memory suggesting the region is responsible for AV memory independent of phonological content contrary to previous proposals. Functional connectivity between angular gyrus and left inferior frontal gyrus and left middle temporal gyrus increased when performing the AV task as naming. The results are consistent with the hypothesis that, at the spatial resolution of fMRI, the regions that facilitate non-linguistic AV associations are a subset of those that facilitate naming though reorganized into distinct networks. | 2022-12-03T17:26:24.640Z |
100,786,596 | {
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} | A NEW CLASS OF DOUBLEhelical molecules has been synthesized The molecules consist of two platinum atoms bridged by a rodlike chain of carbon atoms-along which electrons and charge can flow-surrounded by diphosphine ligands bearing flexible carbon double helices that insulate the rods. "The flexible sp 3 carbon chains wind around the rigid sp carbon chain just like climbing beans wrap around a beanpole," explains John. A. Gladysz, chemistry professor at the Institute for Organic Chemistry University of Erlangen-Nuremberg, in Germany. Gladysz carried out the work with colleagues there and at the University of Utah [ Angew. Chem. Int. Ed. , 41, 1871 (2002)]. "The template effect of a beanpole was known to ancient agrarian societies but has never been exploited on a molecular scale," he continues. The group used two strategies to prepare the compounds. A "directed synthesis" employed a series of organometallic reactions, including an alkene metathesis step using a ruthenium catalyst. Then, in a self-assembly ... | 2022-02-10T10:56:05.758Z |
124,255,434 | {
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"DOI": "10.1109/WVM.1989.47111",
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} | Empirical findings are reported that delineate properties of the process underlying the perception of structure from motion (SfM). First, it is shown that the usual rotating kinetic depth displays generally involve at least two sources of information: relative motion parallax and changes in the projected envelope of the rotating object. Then, evidence is presented that even when variations in projected envelope are minimized, altering the 3-D motion of an object can greatly affect its perceived shape in ways that hint at properties of the underlying process. It is also shown that circular patterns of relative motion parallax not associated with a rigidly moving object can elicit the perception of depth variation, and that added image rotations which by themselves do not elicit apparent depth variation can nevertheless influence the apparent shape of such circular patterns.<<ETX>> | 2022-09-12T05:30:55.546Z |
3,495,787 | {
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"DOI": "10.3390/s17122816",
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"status": "GOLD",
"url": "https://www.mdpi.com/1424-8220/17/12/2816/pdf?version=1512474933"
} | A submicron pixel’s light and dark performance were studied by experiment and simulation. An advanced node technology incorporated with a stacked CMOS image sensor (CIS) is promising in that it may enhance performance. In this work, we demonstrated a low dark current of 3.2 e−/s at 60 °C, an ultra-low read noise of 0.90 e−·rms, a high full well capacity (FWC) of 4100 e−, and blooming of 0.5% in 0.9 μm pixels with a pixel supply voltage of 2.8 V. In addition, the simulation study result of 0.8 μm pixels is discussed. | 2022-12-02T10:44:47.933Z |
83,707,314 | {
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"DOI": "10.2134/AGRONJ1994.00021962008600060018X",
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} | Winter wheat (Triticum aestivum L.) yield varies greatly among landscape positions in the Palouse region of eastern Washington, yet N fertilizer is typically applied uniformly. Varying N fertilizer rates within fields to match site-specific N requirements can increase fertilizer use efficiency; however, spatially variable N management programs are limited by their ability to predict site-specific yield potentials and the resultant N requirements. The objective of this study was to ascertain the role of yield components and soil properties in determining soft white winter wheat grain yield and protein when N application rates are varied among landscape positions. Nitrogen fertilizer (0 to 140 kg N ha −1 ) was fall-applied on footslope, south-backslope, shoulder, and northbackslope landscape positions at each of two farms in 1989 and in 1990. Grain yield among landscapes varied by up to 55% in 1990 and by up to 33% in 1991. Landscape position grain yields increased by 199 kg ha −1 /(cm precipitation+soil water reduction) (r 2 = 0.51) and by 706 kg ha −1 per 100 spikes m −2 (r 2 = 0.76). Grain protein concentration among landscapes increased by 2.7 g kg −1 per each increase of 10 kg residual soil NO 3 -N ha −1 (r 2 = 0.82). The large differences in grain yield among landscape positions may justify spatially variable N application. Improved N management should favorably reduce soft white winter wheat protein concentrations by minimizing high residual N levels as well as improve net returns and reduce environmental degradation. The basis for this improved N management may be site-specific yield estimates calculated from soil water availability and spike density | 2023-01-01T16:39:24.966Z |
136,787,693 | {
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"DOI": "10.4028/www.scientific.net/AMR.700.175",
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} | According to the different powder oil ratio of asphalt mixture rutting experiment at high temperature, rotary experimenting machine, for different powder oil ratio dynamic shear experiment of asphalt mortar, using the scanning electron microscope observation on the microstructure of asphalt mortar, powder oil ratio on mixture high temperature stability influence. The experiment results show that: powder oil ratio is larger, stronger anti rut ability, and powder oil ratio is affected by the asphalt shear strength to influence high temperature stability of asphalt mixture, and put forward the best powder oil ratio in the range of 0.18~1.2. | 2022-02-09T10:57:49.832Z |
24,508,025 | {
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} | One of the leading reasons for emergency department visits happens to be chest pain and shortness of breath with estimated 6.3 million visits for chest pain and 3 million visits for shortness of breath. Over the years, there has been an upward trend in these demographics. The primary workup is usually toward cardio pulmonary causes. Paraesophageal hernia is a term to describe the herniation of gastroesophageal junction and the gastric fundus through the paraesophageal membrane. Paraesophageal hernias account for 5% of all the hiatal hernias, and patients are usually asymptomatic or have complaints of gastroesophageal reflux. However, on rare occasions, they are notorious to develop complications such as incarceration, gangrene, obstruction of intrathoracic stomach, collapse of the lung, and even death. We take this opportunity to present a 49-year-old man who presented with shortness of breath and chest pain. The initial workup revealed a pulmonary embolism on a computerized tomography scan. However, with better clinical judgment and more imaging, he was diagnosed with a paraesophageal hernia with gastric obstruction and early strangulation causing his symptoms. | 2022-02-12T18:37:42.173Z |
110,683,515 | {
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"DOI": "10.4028/www.scientific.net/KEM.516.337",
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} | In the previous report, the operation interface for multi-axis controlled machine tools was developed by using the haptic device that is used in the field of virtual reality and it was changed from a haptic device with 3-DOF to that with 6-DOF. In order to improve the system, more useful functions should be added. In this report, the function to guide the tool in consideration of the tools characteristics is developed. The square end mill cannot cut at its bottom part. So, when the bottom part contacts the removal shape, the square end mill should be guided into a posture contacting at the side part by the force sense. The experiment supposed that the machining of the curved surface had been done. In the case of using the developed function, the number of contacts at the bottom part of the tool was decreased. As a result, the usefulness of the developed function was confirmed. | 2022-02-10T04:51:14.944Z |
253,368,439 | {
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"DOI": "10.56397/sssh.2022.11.06",
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"url": "https://www.paradigmpress.org/SSSH/article/download/279/251"
} | As companies place greater emphasis on human resource management, reward management systems are increasingly being introduced to motivate employees and improve individual and organisational performance. The purpose of this paper is to discuss the objectives of reward management systems, best practices of reward management systems and how these practices can positively or negatively impact on the development of objectives. In addition to this, the drawbacks of reward power and transformational leadership from a gender perspective will also be explored. Using some typical examples, such as the bankruptcy of Enron, this paper concludes that managerial power and transformational leadership approaches are flawed and exaggerate the power of leaders in corporate decision-making. Companies should adopt both benchmarking and 360-degree feedback and focus more on ethical corporate culture, effective leadership and flexible compensation management systems to maximise the positive outcomes of best practice in compensation management systems. | 2022-11-18T00:47:48.682Z |
81,687,010 | {
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"DOI": "10.1017/S0043174500052243",
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} | In greenhouse experiments, conidia of Colletotrichum truncatum applied in an invert emulsion formulation controlled hemp sesbania 100% in the absence of a dew treatment. In field experiments, hemp sesbania control averaged 95 and 97% in 1989 and 1990, respectively, when this formulation was applied to hemp sesbania seedlings using tractor-mounted, air-assist nozzles. This level of weed control was comparable to that achieved from the herbicide acifluorfen. These results indicate that C. truncatum has excellent potential as a mycoherbicide for controlling hemp sesbania and that this potential can be augmented by formulating the pathogen as an invert emulsion. | 2022-12-12T19:59:08.208Z |
229,081,641 | {
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"DOI": "10.36622/vstu.2020.19.2.012",
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} | Кариес является одной из актуальной проблем современной стоматологии и занимает первое место по частоте и интенсивности среди всех стоматологических заболеваний. Установлено, что поражение зубов кариесом - это заключительный этап взаимодействия многих эндогенных и экзогенных факторов, индивидуальных для каждого пациента. Большинство научно-исследовательских работ по изучению причин возникновения кариеса зубов доказывают, что непосредственным этиологическим фактором является локальное изменение pH под биопленкой, фиксированной на поверхности зуба, вследствие расщепления углеводов микроорганизмами и образования органических кислот. Следует упомянуть, что трилистник Кейза служит графической моделью теории возникновения кариеса в современной стоматологии, в которой равноценны три состояния, а именно кариесогенная флора, легкоферментируемые углеводы, низкая кариесрезистентность эмали. Последнюю в свою очередь определяют микротвердость, кислотоустойчивость и проницаемость. В понимании комплексной заботы о здоровье человека, и прежде всего детей, на первый план выступает превентивная точка зрения. Учитывая результаты «поперечного» эпидемиологического исследования на распространенность и интенсивность кариеса зубов у детского населения, прямое и непосредственное влияние оказывают, во-первых, экологические факторы, например, низкое содержание фторида в питьевой воде, загрязнение окружающей среды, неблагоприятные климатические условия. Во-вторых, социально-экономические, такие как ограниченная доступность стоматологической помощи, низкий уровень жизни и образования, характер питания, недостаточная заинтересованность в вопросах сохранения здоровья полости рта. Низкий уровень мотивации, санитарно-гигиенических знаний детского населения к сохранению стоматологического здоровья является фактором высокого риска развития патологического процесса твердых тканей, молочных и постоянных зубов детей. Резюмируя вышеизложенное, считается актуальным систематизация факторов риска возникновения кариеса для современного стоматологического просвещения детского населения, родителей и педагогов с упором на этиопатогенез
Caries is one of the most urgent problems of modern dentistry and ranks first in frequency and intensity among all dental diseases. It is established that dental caries is the final stage of interaction of many endogenous and exogenous factors, individual for each patient. Most research studies on the causes of dental caries prove that the direct etiological factor is a local change in pH under the biofilm fixed on the tooth surface, due to the breakdown of carbohydrates by microorganisms and the formation of organic acids. It should be mentioned that the case trefoil serves as a graphic model of the theory of caries occurrence in modern dentistry, in which three conditions are equivalent, namely cariesogenic flora, easily fermentable carbohydrates, and low caries resistance of enamel. The latter, in turn, is determined by microhardness, acid resistance, and permeability. In the understanding of comprehensive care for human health, and especially for children, the preventive point of view comes to the fore. Taking into account the results of the "cross-section" epidemiological study, the prevalence and intensity of dental caries in the child population are directly and directly influenced, first, by environmental factors, such as low fluoride content in drinking water, environmental pollution, and unfavorable climatic conditions. Second, socio-economic factors, such as limited access to dental care, low standard of living and education, nutritional status, and lack of interest in maintaining oral health. The low level of motivation, sanitary and hygienic knowledge of the children's population to maintain dental health is a high risk factor for the development of the pathological process of hard tissues and milk, and permanent teeth of children. Summarizing the above, it is considered relevant to systematize the risk factors of caries for modern dental education of children's population, parents and teachers with an emphasis on etiopathogenesis | 2022-01-27T01:47:48.351Z |
127,890,888 | {
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} | This chapter describes the sites of Ras Es-Salmeh such as Abu Tahah, el-Beyaz (A), el-Beyaz (B), Jelamet Hamul, en-Naqb and el-Mabhashiyyeh. The registration of this site includes site number that consists of the serial number (consecutive numbering for each landscape unit, from west to east and from north to south) and the scientific number, and site name that is based upon the Arabic name as used today by the inhabitants. Additionally, information on reference point, elevation, type of name, site type, area of the site, topography, rock and soil type, cultivation, water and roads, and visibility are also provided for each site.Keywords: Abu Tahah; el-Beyaz (A); el-Beyaz (B); el-Mabhashiyyeh; en-Naqb; Jelamet Hamul; Ras Es-Salmeh | 2022-02-09T15:46:59.277Z |
102,528,246 | {
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} | The use of industrial organic waste which are chitosan and propolis as materials for the development of biodegradable and active packaging is economical and environmentally appealing. Processing of propolis-chitosan film can minimize waste, and produce low-cost added value biopolymer packaging films for targeted applications. This aims of this research is to develop and characterize a biodegradable films by incorporating chitosan with propolis extract to enhance the functional properties for potential use as active food packaging. The film’s moisture content, solubility and antimicrobial activity increase due to increasing volume of propolis extract which are 0 ml, 1.2 ml and 2.4 ml of propolis extract. Propolis-chitosan film with 2.4 ml of propolis extract is more soluble in water compared to propolis-chitosan film with 0 ml of propolis extract and 1.2 ml of propolis extract. The higher the volume of the propolis extract used, the higher the solubility of film in the water. The moisture content also will... | 2022-03-12T10:07:32.365Z |
36,302,320 | {
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"DOI": "10.1109/LCOMM.2015.2512269",
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} | Multiple-input multiple-output systems with spatial modulation (MIMO-SM) have been recently proposed for high data rate, low complexity transmission schemes. However, in the SM, the antenna of the transmitter is randomly activated by the spatially modulated information bit sequence. Due to bad conditions of the active antenna's channel determined by the SM technique, the system would be likely to transmit frame with errors. This causes a significant reduction in the system performance. In this letter, to eliminate the bad effects of the channel assignment of the SM, we propose a novel SM-based MIMO system with index modulation technique (SM-MIMO-IM) when operating over i.n.d. and i.i.d. Rayleigh fading channels. The average symbol error rate (SER) and bit error rate (BER) of the proposed scheme are derived. It can be seen from numerical results that SM-MIMO-IM provides significant performance improvements and additional diversity gain compared to the classical SM and other some techniques given in the literature. Furthermore, the proposed mathematical analyses have been verified through the Monte-Carlo simulations. | 2022-06-07T18:36:06.716Z |
244,530,508 | {
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} | A non-linear future is much indebted to the rear-view mirror. [...]in answer to Morreira's question on the impact of the Covid-19 pandemic, one could argue that, due to structural inequalities inherited from the apartheid era and compounded by corruption and lip service to transformation under the ruling African National Congress (ANC) government, in South Africa, despite timely national state of disaster and prolonged lockdown measures taken to mitigate the explosive proliferation of Covid-19, the country has still emerged as having the most cases and the most deaths in Africa so far. [...]far from radically disrupting established hierarchies of inequalities in livelihoods, Covid-19 has mostly preyed upon and in some instances exacerbated existing victimhood and vulnerabilities. There is concern as well that the loan approved by the International Monetary Fund (IMF) to mitigate the negative economic effects of Covid-19 has only compounded the precarious situation of the South African poor, for a range of reasons, among which the IMF's notoriety as a cure that is often more dangerous than the disease. Taking cognizance of how what matters intersects in a given context is useful in bringing out the complexities and nuances in the situations and relationships that we are interested in exploring and explaining. Since publication of the book, I have become increasingly interested in how we could develop a framework of incompleteness as a replacement for the current dominant framework of completeness and the pursuit of superiority through zero-sum games of conquest and absolutes, violence and violations. | 2022-06-14T22:51:52.151Z |
243,154,791 | {
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"url": "https://tcsj.utc.edu.vn/index.php/tcgtvt/article/download/714/596"
} | Trong khai thác đường sắt, khi sản xuất mới hoặc cải tạo toa xe, đoàn tàu sử dụng hãm gió ép phải đảm bảo khoảng cách hãm khi dừng, quy định không quá 800 m với khổ đường 1000 mm. Bài báo trình bày cơ sở lý thuyết tính khoảng cách hãm đoàn tàu, toa xe theo phương pháp giải tích với cách tính tích phân và cách tính phân đoạn, từ đó xây dựng chương trình tính toán kiểm nghiệm khoảng cách hãm toa xe khách sử dụng trên đường sắt Việt Nam trên cơ sở ngôn ngữ lập trình VBA. Kết quả tính toán cho thấy, cách tính tích phân phù hợp hơn và có thể ứng dụng chương trình tính toán đã thiết lập để kiểm nghiệm khoảng cách hãm toa xe sử dụng trên Đường sắt Việt Nam. | 2022-07-10T05:49:28.267Z |
160,200,855 | {
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} | An amazing example of uncritical dogmatism in New Testament studies is the belief that the Synoptic Gospels should be dated after the Jewish War of A.D. 66-70 because they contain prophecies eventu of the destruction of Jerusalem by the Romans in the year 70. Usually this chronology is accepted without any discussion, although the prophecies found in Mark 13.1-37 and other places have been dated in very different ways. Scarcely any efforts are made to defend such a post-war date. When such attempts are made, the following passages are referred to, here quoted in the order of the common Synoptic narrative: Luke 19.43-44, Matthew 22.7, and the Synoptic apocalypse in Matthew 24.1-25.46 and parallels. An analysis of these prophecies will have to make it evident that none of them corresponds to what is known about the Jewish war and the destruction of Jerusalem. Keywords: destruction of Jerusalem; Jewish War; Luke 19.43; Mark 13.1; Matthew 22.7; New Testament studies; Synoptic Gospels | 2022-09-15T00:50:34.533Z |
144,402,055 | {
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"DOI": "10.1080/00224549909598419",
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} | Abstract The author assessed the relationships between group identities and endorsement of (a) national strength and order and (b) international harmony and equality, important frames of reference for the individual. The respondents were 231 Australian psychology undergraduates (158 women, 73 men). Results of hierarchical regression analysis showed that the best predictor of endorsement of national strength and order was the identity of capitalist, whereas the identities of socialist, environmentalist, and global citizen best predicted the endorsement of international harmony and equality. | 2022-09-15T07:59:44.361Z |
197,609,521 | {
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} | This work presents the design and the latest experimental results on the surface strain measurements during an impact event obtained with the EXTREME high-speed shearography instrument. The shearography technique is used in this project to provide a quantitative measurement of the surface strain development at the first moments of the impact event (μs time scale) which may reveal the initiation of the failure mechanisms in composite materials. Experimentally measured surface strain components over the field of view will be used as input and validation data for new numerical and analytical models of the impact response of composites. The new configuration of the shearography instrument realises measurements of the in- and out-of-plane surface strain components to improve coupling with the numerical models. Two viewing directions (shearing interferometers) with a double-frame approach are used to capture the interferograms during the impact. The interferometers realise a double-imaging Mach-Zehnder scheme for the spatial phase-shifting with independent control of the shearing amount and the carrier frequency. The set of technical parameters of the developed shearography instrument makes it one of the most extreme applications of shearography for material characterisation. The framework for this work is the “EXTREME Dynamic Loading – Pushing the Boundaries of Aerospace Composite Material Structures” Horizon 2020 project. | 2022-12-16T15:40:33.801Z |
44,107,008 | {
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"DOI": "10.1364/OE.26.012948",
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} | The singular value decomposition ghost imaging (SVDGI) is proposed to enhance the fidelity of computational ghost imaging (GI) by constructing a measurement matrix using singular value decomposition (SVD) transform. After SVD transform on a random matrix, the non-zero elements of singular value matrix are all made equal to 1.0, then the measurement matrix is acquired by inverse SVD transform. Eventually, the original objects can be reconstructed by multiplying the transposition of the matrix by a series of collected intensity. SVDGI enables the reconstruction of an N-pixel image using much less than N measurements, and perfectly reconstructs original object with N measurements. Both the simulated and the optical experimental results show that SVDGI always costs less time to accomplish better works. Firstly, it is at least ten times faster than GI and differential ghost imaging (DGI), and several orders of magnitude faster than pseudo-inverse ghost imaging (PGI). Secondly, in comparison with GI, the clarity of SVDGI can get sharply improved, and it is more robust than the other three methods so that it yields a clearer image in the noisy environment. | 2022-12-13T11:27:55.106Z |
91,453,765 | {
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"DOI": "10.4314/GJPAS.V24I2.5",
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} | The effect of ethanolic extracts of Persea americana seed and Zea mays silk on blood glucose levels, body and organ weights of alloxan- induced hyperglycemic Wistar rats was investigated using standard analytical techniques. Thirty male albino rats weighing 120-161g were randomly assigned to six groups of five rats each. Groups 3- 6 were test groups which received 400 mg/kg body weight Persea americana seed single extract, 400 mg/kg body weight Zea mays silk single extract, 400 mg/kg body weight combined extract of Persea americana seed and Zea mays silk and 500 mg/kg body weight combined extract of Persea americana seed and Zea mays silk repectively. Group 1 and 2 served as normal and diabetic controls respectively. Diabetes was induced using 170mg/kg body weight alloxan monohydrate. All the rats received their normal diet and distilled water daily for a period of 28 days. At the end of the experiment, the groups administered 400 mg/kg body weight Zea mays silk single extract and 400 mg/kg body weight combined extract of Persea americana seed and Zea mays silk showed significant (P< 0.05) decrease in fasting blood glucose when compared with the diabetic control. The highest body weight change was observed in the high dose combined extract group followed by the Zea mays silk single extract group. Apart from the kidney and spleen weights, which were significantly reduced in the Zea mays single extract group, there was no significant difference (P> 0.05) in organ weights of the experimental groups compared with the diabetic and normal controls. Persea americana seed increased body and organ weights of experimental animals whereas Zea mays silk decreased same. It may therefore be concluded that Persea americana seed and Zea mays silk are probable hypoglycemic agents.Keywords: Persea americana seed, Zea mays silk, glucose, body weight, organ weight | 2023-01-01T17:44:45.213Z |
14,680,113 | {
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"DOI": "10.1109/BMEI.2010.5639661",
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} | A computer aided measurement and analysis system is designed to avoid the problem caused by Orthodontics Mould (Teeth Die) manual measurement of the possible measurement errors in this paper. Orthodontics Mould's digital image may be collected by using digital CCD camera's information acquisition technology, and achieved by means of a computer-aided measurement system of the Orthodontics Mould's digital image. Digital image processing of the Orthodontics Mould makes it easy to process and analyse the measurement data from the mould. The system based on the Windows platform, Visual C++6.0 tools and MS SQL Server database technology completes Orthodontics Mould-image data measurement, processing, maintenance and management. The System based on the arch form's measurement and analysis includes three subsystems, namely, Orthodontics Mould's medical records management system, measurement systems and analysis system. The clinical results show that the computer aided measurement and analysis system for Orthodontics Mould has good performances,which provides dentists with a more objective evaluation method. | 2022-02-13T02:29:51.342Z |
31,311,078 | {
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"DOI": "10.1177/003591571701000930",
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"status": "BRONZE",
"url": "https://journals.sagepub.com/doi/pdf/10.1177/003591571701000930"
} | IN October, 1914, I published' five cases in which a post-operative tympanites, threatening to cause immediate death, was treated by making an intestinal fistula, and four of the patients recovered. The tympanites was attributed to an increased resistance to the passage of the intestinal contents, associated with an enfeebled peristaltic action, and especially to delay in the large intestine, these being regarded as effects of exposure and manipulation of the abdominal contents during the operation. It was suggested that the condition might be described as one of " acute intestinal stasis." In 1915, Professor Arthur Keith2 recorded the results of investigations into the nature of certain areas of nodal neuro-muscular tissue which consist of specializations of AXierbach's plexus of nerves. These areas of nodal tissue are situated at various parts of the alimentary canal where delays in the passage of its contents normally take place, for example at the ileo-caecal valve and at the pylorus. Professor Keith concluded that the nature and functions of the myenteric plexus of the intestine are physiologically similar to those of the nodal and conducting system in the heart, and that each specialized nervous area is the originator and regulator of peristaltic activity in the section of bowel immediately beyond it. He pointed out that a want of co-ordination between the muscular activity of the various sections of the alimentary canal may give rise to effects comparable to those of heart block, and argued that the condition of intestinal stasis is produced in this way. The application of Keith's explanation of intestinal stasis to the condition which I ventured to call an acute intestinal stasis aids greatly the understanding of the nature of a post-operative tympanites. In the course of a satisfactory convalescence from an uncomplicated operation | 2022-02-12T11:52:28.083Z |
224,870,599 | {
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"DOI": "10.1049/IET-GTD.2020.0784",
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} | A modified tangent vector (TV)-based voltage stability constrained optimal power flow method is proposed. The proposed method determines an optimal stable equilibrium point (SEP) satisfying the required voltage stability margin (VSM) considering limit-induced bifurcation (LIB). LIB, which occurs when a generator reaches a reactive power limit during load increasing, may cause an optimistic overestimation of voltage stability and inadequate operation. The key of the proposed method is to use approximated TV for considering LIB as a voltage stability constraint to ensure that the solution becomes an SEP and to avoid inappropriate operation caused by LIB. The validity of the approximation is evaluated analytically and numerically in this study. The threshold for the approximated TV is updated based on the continuation power flow calculation result to satisfy the required VSM. The proposed method was implemented on MATPOWER, and evaluated with a 2-machine 4-bus system and an IEEJ standard WEST10-O/V system. The results show that the proposed method can determine the optimal SEP satisfying the required VSM even if LIB occurs. | 2022-04-22T04:45:12.909Z |
2,473,711 | {
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"DOI": "10.1109/BIBM.2016.7822630",
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} | Paroxysmal sympathetic hyperactivity (PSH) is an important clinical problem of severe traumatic brain injury (TBI) which incurs approximately 90% of all TBI-related costs. However, current detection approach is hampered by no consensus clinical diagnostic criteria, paroxysmal episode feature with complex manifestations, and already overloaded clinical activities. These limitations cause delayed recognitions which result in poor clinical outcomes. In this paper, we design an integrated Medical Cyber-Physical System (Medical CPS) for early detection of paroxysmal sympathetic hyperactivity patients. First, a formal model is proposed to describe clinical diagnostic criteria. With the formalized models employed, we implement an early detector and integrate it with revised medical device adapters into Medical CPS. Our system will monitor patient conditions automatically and continuously to relieve medical staff from the heavy burden of clinical activities and provide timely decision supports. Evaluations on 107 clinical cases extracted from medical publications demonstrate the effectiveness and the efficiency of our integrated system. | 2022-06-14T05:53:57.010Z |
247,833,517 | {
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"DOI": "10.4103/rcm.rcm_67_21",
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},
"license": "CCBYNCSA",
"status": "GOLD",
"url": "https://doi.org/10.4103/rcm.rcm_67_21"
} | Background: Transcatheter pulmonary valves (TPVs) are feasible and much less invasive options for surgical right ventricular outflow tract (RVOT) repair or valve replacement in patients with degeneration of the pulmonary valve bioprosthesis or RVOT conduit failure. In 2005, the first Sapien valve was implanted in the pulmonic position, and proceeding In March 2016, the Food and Drug Administration approved the SAPIEN valve (Edwards Lifesciences) for use in malfunctioning RVOT conduits. Material and method: We describe the first ten cases of TPV-in-valve procedure conducted in our center, along with the patients' prior surgical history, procedural details, and their clinical and echocardiographic data. Result and conclusion: Our data provided safety and efficacy of transcatheter valve-in-valve procedure in degenerated pulmonary bioprotheses and our follow-up proved durability of this procedure. | 2022-04-05T14:25:31.791Z |
42,104,154 | {
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"DOI": "10.1117/12.2007575",
"MAG": "1988656386",
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} | The description of space-time patches is a fundamental task in many applications such as video retrieval or classification. Each space-time patch can be described by using a set of orthogonal functions that represent a subspace, for example a sphere or a cylinder, within the patch. In this work, our aim is to investigate the differences between the spherical descriptors and the cylindrical descriptors. In order to compute the descriptors, the 3D spherical and cylindrical Zernike polynomials are employed. This is important because both the functions are based on the same family of polynomials, and only the symmetry is different. Our experimental results show that the cylindrical descriptor outperforms the spherical descriptor. However, the performances of the two descriptors are similar. | 2022-08-26T06:21:06.380Z |
17,263,964 | {
"externalids": {
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"ArXiv": null,
"DOI": "10.1109/AICI.2009.427",
"MAG": "2088772293",
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} | In this paper, we research a class variational image inpainting models with total variation regularization. Using a splitting technique, an iterative procedure of alternately solving a pair of easy subproblems is constructed. The proposed approach has fast speed than state-of-the-art methods which need to calculate Euler-Lagrange equation. The experiments show that our algorithm visually can obtain a natural and believable inpainting results for filling in missing or damaged regions of an image. | 2022-09-13T23:07:02.282Z |
153,594,602 | {
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"DOI": "10.1080/09603100802599498",
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} | This study directly examines the empirical relationship between corporate value and three distinct ownership structures using data from Canada, where the security laws and shareholder protection conditions are similar to those of the US (La Porta et al., 1999) but corporate control tends to be more concentrated (Holderness et al., 1999). Ownership structure is classified in three ways: dual class firms, single class closely-held firms and widely-held firms. The focus of this article is to test for the impact of concentrated control on corporate value using either dual class or single class closely-held ownership structure. The empirical results, using both fixed and random effects estimation methods, show that after controlling for size, financial leverage, percentage of outside directors and industry differences, dual class companies sell at a significant discount compared to closely-held single class companies. Consistent with Claessens et al. (2002), and Gompers et al. (2004) dual class structure in Canada lessens corporate value because it lowers shareholder and manager alignment and increases agency problems. We also find that pyramid structure has a negative impact on value in both dual class and single class closely-held companies. | 2022-09-14T21:58:17.807Z |
234,921,551 | {
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"DOI": "10.1109/ICAECT49130.2021.9392452",
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} | Adder is considered the principle unit of every arithmetic and logical operation. Carry select adder (CSLA) is an adder that helps to speed up operations of several arithmetic function. To further improve the speed, an idea of incorporating more than one high speed adder logic within a regular CSLA is employed. This paper discusses the design of a hybrid CSLA which utilizes the advantages of both Kogge Stone adder and look ahead adder (CLA) to obtain higher speed. Kogge Stone adder is a particular type of Adder and hence it is widely regarded as one of the high speed addition methods due to faster carry generation. Look ahead adders are employed in the initial stages of the modified adder to boost its speed as its computation performance is better if the number of bits are less. A 64-bit hybrid CSLA is implemented, in Xilinx Spartan 6 FPGA development board. The modified hybrid carry select adder is found to improve the speed and provides better results on energy requirement and speed compared to other carry select adders. | 2022-12-03T23:03:56.713Z |
120,561,152 | {
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"DOI": "10.1117/1.2032107",
"MAG": "1991569942",
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} | The images on a dot-matrix hologram consist of many 2-D grating dots with different pitches and orientations. Only some specified pitches and 256 specified orientations are usually employed. The difference between any two pitches to show different colors is more than 0.1 µm; therefore, it is possible to hide several extra pitches in a specified pitch. If all the extra pitches are almost equal to the specified pitch, grating dots with extra pitches will be of nearly the same color as the specified pitch. When a laser beam is incident on the dot-matrix hologram with hidden pitches, data for the hidden pitches will be decoded by the diffraction pattern of the grating dots of the hologram. A specified grating orientation can be used to hide extra grating orientations similarly. What's better, mixing the above two hiding techniques is possible. | 2022-02-09T22:14:27.467Z |
21,745,066 | {
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"ArXiv": null,
"DOI": "10.1109/SIBGRAPI.2017.40",
"MAG": "2768034282",
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} | The popularity of applications using Augmented Reality, especially due to the dissemination of smartphones with high processing power, introduces the need for Fiducial Markers that can be detected quickly, with good accuracy and can deal with partial occlusion. Fiducial Markers can have different shapes, sizes, structure and colors, and are inserted into a scene to facilitate the detection and consequent projection of virtual objects. In particular, this paper proposes a new Color-based and Recursive Fiducial Marker (CRFM), which is constructed by square-based geometric forms and uses different colors to produce a recursive structure that was designed to still work under partial occlusion. We describe the CRFM design and how its detection mechanism works. Our evaluation results show that CRFM achieves a good level of accuracy. Moreover, we show that the detection of the CRFM can be as fast as a board of ArUco, where only black and white colors are used. | 2022-10-29T16:49:43.643Z |
216,348,371 | {
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"DOI": "10.19090/hk.2019.3.20-40",
"MAG": "3009768305",
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"license": "CCBYSA",
"status": "HYBRID",
"url": "http://hungarologiaikozlemenyek.ff.uns.ac.rs/index.php/hk/article/download/2172/2181"
} | A XIX–XX. szazad fordulojanak magyar irodalmat meghatarozo kisregeny megujulasa lenyegbevago modon alakitotta at a korszak prozajat, tobb kulonboző tipusu elbeszelesformat letrehozva, mely sajat statusaban teremti ujja a műfajt. Valamennyi kisregeny (peldaul Toldy Istvan: Anatole, Asboth Janos: Almok almodoja, Reviczky Gyula: Apai orokseg) jellemzően a szubjektum elbeszelhetősegenek lehetősegeit kutatja, s ehhez a szovegegyutteshez sorolhato a műveszetet es a műveszi letmodot kutato regenytipus is. A tanulmany az első magyar műveszregeny altal felvetett problemakomplexum kerdeseivel foglalkozik. Justh Zsigmond Műveszszerelem cimű regenye ugyanis a műveszettel valo talalkozas soran feltarulo erzelmi, hangulati tapasztalat nyelvi-szemantikai aspektusait mutatja fel a korszak jellegzetes kepzőműveszeti (impresszionista) eszmeinek bevonasaval. | 2022-12-21T00:45:14.859Z |
40,903,544 | {
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"DOI": "10.1331/JAPhA.2012.12530",
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} | 1The acute physiology and chronic health evaluation (APACHE) II score was developed and validated for use among intensive care unit (ICU) patients, but its utility among non-ICU patients is unknown. Retrospective data from about 200 patients were abstracted, including illness severity (APACHE II score); inhospital vital status at 48 hours, 7 days, 14 days, and 30 days following the start of methicillin-resistant Staphylococcus aureus (MRSA)-targeted therapy; and notation of an ICU admission at the time of MRSA bacteremia onset. In-hospital mortality and overall mortality were modeled using logistic regression at each time point using APACHE II scores for ICU and non-ICU patients. A model that included APACHE II scores was compared with an age-adjustment-alone model among all patients. APACHE II was a significantly better predictor of death at all time points in both ICU and non-ICU patients compared with random prediction and significantly improved the prediction of overall and 48-hour mortality compared with age adjustment alone. Implications. Differences in disease severity in acute treatment episodes for seriously ill patients can be a vexing confounding factor in comparative effectiveness studies. This work provides a validated measure that can be used to control for confounding based on sound physiologic principles. Development and validation of other measures for this purpose (i.e., confounding) that can have widespread acceptance for incorporation into comparative effectiveness studies are needed. Health symptoms and disability Patterson et al. 2 reported that pain and fatigue were “found to partially mediate the effects of disability on self-reported general health status and physical functioning.” A sample of 12,249 adults 40 years or older provided responses to questions about symptom prevalence and frequencies for 21 commonly reported symptoms, self-perceived health status, physical functioning, number of medications, and demographic variables. Adults with disability reported significantly greater prevalence and frequencies for all 21 symptoms, with pain and fatigue being the most common. Implications. Managing medication therapies that minimize pain and fatigue can have a considerable impact on patient quality of life. Other studies have shown the correlation between disability and independent living. A compelling study for the future might be one that examines the association between medication therapy management and independent living. Pharmacists and diabetes management teams Pepper et al. 3 concluded that “a pharmacist as a part of the diabetes management team may result in lower A1C in patients with more advanced and uncontrolled type 2 diabetes mellitus versus a health care team without a pharmacist.” Their conclusions were based on assessment of the change in glycosylated hemoglobin (A1C) for patients with type 2 diabetes in outpatient clinics. Patients were assigned to either the pharmacist (n = 86) or nonpharmacist (n = 86) group, depending on | 2022-01-27T18:35:52.246Z |
246,763,572 | {
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"DOI": "10.30587/indexia.v3i2.2925",
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},
"license": "CCBY",
"status": "GOLD",
"url": "http://journal.umg.ac.id/index.php/indexia/article/download/2925/1974"
} |
Creative Color Gresik is a convection company engaged in the production of jersey making which is located in the city of Gresik, East Java. The production carried out is jersey printing for sports clothes to clothes for the team. The problem that is obtained after observing is the customer who wants to order a jersey at PT. Creative Col-or Gresik still doesn't have a picture of the jersey he wants to make. The number of designs that exist in PT. Creative Color Gresik, makes customers feel confused in making choices. Each design has a different motif and color. The development of a jersey design recommendation system using the item based collaborative filtering method can assist in providing jersey design recommendations that can assist customers in determining the design to be made according to the results of the recommendations generated. The test results of the item based collaborative filtering method using questionnaire testing obtained an accuracy of 75% and an error of 25%.
| 2022-02-18T00:44:28.450Z |
136,782,098 | {
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"DOI": "10.9725/KSTLE.2012.28.2.062",
"MAG": "1995840869",
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} | Atomic force microscopy (AFM) has been widely utilized as a versatile tool not only for imaging surfaces but also for understanding nano-scale interfacial phenomena. By measuring the responses of the photo detector due to bending and torsion of the cantilever, which are caused by the interactions between the probe and the sample surface, various interfacial phenomena and properties can be explored. One of the challenges faced by AFM researchers originates in the physics of measuring the small forces that act between the probe of a force sensing cantilever and the sample. To understand the interactions between the probe and the sample quantitatively, the force calibration is essential. In this work, the procedures used to calibrate AFM instrumentation for nano-scale force measurement in normal and lateral directions are reviewed. | 2022-09-14T14:22:15.471Z |
208,186,209 | {
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"DOI": "10.3233/jnd-190441",
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} | The natural history of patients with spinal muscular atrophy (SMA) has changed due to advances in standard care and development of targeted treatments. Nusinersen was the first drug approved for the treatment of all SMA patients. The transfer of clinical trial data into a real-life environment is challenging, especially regarding the advice of patients and families to what extent they can expect a benefit from the novel treatment. We report the results of a modified Delphi consensus process among child neurologists from Germany, Austria and Switzerland about the indication or continuation of nusinersen treatment in children with SMA type 1 based on different clinical case scenarios. | 2022-10-02T14:24:15.540Z |
159,030,405 | {
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"DOI": "10.1080/00343404.2017.1407026",
"MAG": "2778749140",
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} | ABSTRACT Unions have a distanced relationship from the practice of regional governance. Studies of regional governance tend to focus on the role of the state in combination with politically and economically dominant interest groups. In these analyses, and in practice, unions and their members are at best marginal and often absent. The argument presented in this study is that to understand the relative absence of unions, it is necessary to consider the forms and processes of regional governance and the capacities of unions to engage. These themes are addressed with reference to the North West Tasmania region in Australia. | 2022-12-17T23:33:36.539Z |
239,033,057 | {
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"DOI": "10.2139/ssrn.3941712",
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} | Using global ethnography and a grounded theory approach, this paper analyzes the contextual factors that led to the communities of the San Rafael Las Flores region mistrusting the mining corporation (Tahoe Resources), demonstrated through actions of high violence. Generalized trust, through honest relationship development characterized by limiting inequality, is of the great importance for securing a SLO. | 2022-12-19T05:23:04.441Z |
254,961,608 | {
"externalids": {
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"DOI": "10.18050/ingnosis.v6i2.2063",
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"license": "CCBYNC",
"status": "GOLD",
"url": "http://revistas.ucv.edu.pe/index.php/ingnosis/article/download/2063/1792"
} | Objetivo. La presente investigación determina el efecto de las temperaturas de los fluidos de operación en el performance de una torre de enfriamiento de laboratorio. Materiales y Métodos. La investigación es del tipo experimental realizado en el laboratorio de generación termoeléctrica, en la cual se determina el comportamiento del desempeño de la torre de enfriamiento de tiro forzado, tal como el rendimiento térmico, acercamiento y rango. Resultados. Se caracterizó los flujos experimentales para poder evaluar el desempeño de la torre de enfriamiento; para ello, se trabajaron con 4 flujos másicos de agua caliente, cada uno de ellos a temperaturas de 30, 40, 50, 60 y 70 °C. Se elaboraron las curvas de comportamiento de los fluidos actuantes en la torre de enfriamiento, evaluándose el desempeño en función a los valores de temperatura de bulbo seco y bulbo húmedo del aire y las temperaturas del agua de enfriamiento. Conclusión. Para el caso de un flujo de 0.0047 m3/s y una temperatura de entrada del agua caliente de 30 °C, se alcanzó una eficiencia de 91.67 %, con un flujo másico de aire de 0.00421 m3/s de aire caliente a 30 °C y una humedad relativa de 58.6 %, requiriéndose a la salida del proceso, aire caliente con humedad relativa de 92.8 %, con flujo másico de agua de reposición igual a 0.324 m3/h. Los indicadores de desempeño de las torres de enfriamiento son óptimos para el caso del flujo másico de agua caliente igual a 0.00421 m3/s. | 2022-12-23T02:07:40.932Z |
56,411,103 | {
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} | What is a society? What is political power? John Searle claims that previous political philosophers not only neglected these fundamental questions but also lacked the means to effectively address them. Good answers, he thinks, depend on theories of speech acts, intentionality, and constitutive rules irst developed by analytic philosophers. But Searle is mistaken. Early phenomenologists had already developed the requisite theories. Reinach’s philosophy of law includes a theory of speech acts. This theory is based on Husserl’s account of intention‐ ality. Edith Stein extended that account by offering a detailed de‐ scription of collective intentionality. And it was Stein who brought these strands of early phenomenological research together to ad‐ dress the very questions of political philosophy Searle regards as both fundamental and neglected. In this paper, I recount Stein’s answers to these questions and argue that they compare favourably with those of Searle. | 2022-01-27T15:56:11.212Z |
74,481,427 | {
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} | Endoscopic therapy for biliary fistulas should reduce the pressure gradient between the bile duct and the duodenum and promote antegrade flow of bile away from the fistula and into the duodenum. Although several endoscopic methods are effective for sealing biliary fistulas, which is best remains unclear. To determine whether small-diameter stents alone are … | 2022-02-11T08:10:57.580Z |
231,904,587 | {
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"DOI": "10.1177/2372732220984800",
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"url": "https://journals.sagepub.com/doi/pdf/10.1177/2372732220984800"
} | Numerous attempts to improve diversity by way of changing the hearts of decision makers have fallen short of the desired outcome. One underappreciated factor that contributes to bias resides not in decision makers’ hearts, but instead in their minds. People possess images, or mental representations, for specific roles and professions. Which mental image or representation springs spontaneously to mind depends on the current status quo within a field. Whether or not an individual or groups’ appearance matches visual stereotypes results in perceptually mediated preferences and prejudices, both of which harbor pernicious assumptions about who belongs in a professional setting and why. Leveraging these scientific insights can enact change. Shifting visible exemplars can change people’s mental representations and their heart’s evaluative reactions to others. | 2022-10-21T01:18:33.682Z |
11,550,460 | {
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} | Two cases of intracranial hemorrhage due to the congenital deficiency of coagulation factor XIII were experienced. The first case was a 25-year-old man with an intracerebral hemorrhage in the right parieto-occipital region and was treated conservatively by hematological replacement therapy. The second case was a 30-year-old woman with an intracerebral hemorrhage in the parietal region which was surgically treated. Both cases were completely cured. Since Duckert described the first case of the congenital deficiency of coagulation factor XIII in 1960, 93 cases have been reported in the literature. The clinical picture of the intracranial hemorrhage based upon factor XIII dificiency is characterized by a tendency of spontaneous rebleeding 48 hours to several days after temporary cessation of bleeding. Therefore, no case of surgical treatment has been reported yet. The second case showed unconsciousness and intracranial hypertension and was treated by craniotomy and removal of the intracerebral hematoma. Replacement therapy with a factor XIII preparation was given before, during and after the operation. No side effects of the factor XIII replacement therapy were noted. Surgical therapy for the congenital deficiency of coagulation factor XIII might be safe if the patient is controlled by hematological replacement therapy. | 2022-10-07T00:31:23.410Z |
18,096,209 | {
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} | In a previous report we described the use of oligo(dT)-cellulose for the isolation of mRNA-protein complexes from EDTA-dissociated polysomes extracted from normally growing or adenovirus infected KB-cells (I). Experiments presented here provide evidence that proteins involved in these complexes bind specifically to mRNA since: a) the proteins and mRNA cosediment through sucrose gradients, b) they adsorb and elute from oligo(dT)-cellulose together, and c) analysis of the products from ribonuclease digestion experiments show that the poly (A) end and a separate small fraction of the mRNA are resistant to the enzymes and attached to protein. | 2022-09-27T22:59:39.193Z |
94,967,556 | {
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} | Dielectric measurements (permittivity and hysteresis loop) of monocrystals of bis-thiourea pyridinium bromide inclusion compound have revealed for the first time ferroelectric properties of the studied samples. In the present article, a model of ferroelectric ordering on the basis of single-crystal x-ray diffraction data is described. In the low-temperature phase, the spontaneous polarization is directed along the a axis and ferroelectricity is of the mixed type (displacement and order-disorder component), whereas in the intermediate phase the spontaneous polarization is directed along the c axis and ferroelectricity is of the order-disorder type. | 2022-12-03T11:47:12.133Z |
120,270,262 | {
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} | A flux-based modified method of characteristics (MMOC) methodology in 1D is described which has the following properties: unconditional stability (though explicit), exact answers for integer CFL (Courant) numbers, completely conservative (locally and globally) and able to utilize various flux limiters and various characteristic- (trajectory-) tracking algorithms. The use of characteristics based on cell-wise constant characteristic velocities results in considerable code simplification, and Van Leer's MUSCL is an accurate and cost-effective flux limiter. For CFL≥1 the flux limiter is applied only to the non-integer part of CFL, whereas the integer part is exact for constant velocities; therefore accuracy improves with larger CFL. It is not a cheap algorithm, although explicit, because the operation count per time step increases with the integer part of CFL, but it is much more accurate than the commonly used implicit upstream differencing. This flux-based MMOC method is well suited for groundwater flow calculations in which large local Courant numbers arise owing to grid clustering. | 2022-12-17T07:27:31.327Z |
251,946,461 | {
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"DOI": "10.1109/CyberneticsCom55287.2022.9865585",
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} | A web-based online complaint portal is one of the e-government public services. The complaint's content must be categorised in order for it to be transmitted to the appropriate agency swiftly and properly. The most often used standard classification algorithms are the Naive Bayes Classifier (NBC) and k-Nearest Neighbor (k-NN), both of which classify just one label and must be tuned. The purpose of this project is to categorize complaint messages that include several labels simultaneously using NBC tuned for particle swarm optimization (PSO). The data source is the Open Data Jakarta and is partitioned into 70% training data and 30% test data for classification into seven labels. The NBC and k-NN algorithms are used to compare PSO's optimization performance. Cross-validation ten times revealed that optimizing NBC with PSO obtained an accuracy of 88.16%, much superior than k-NN at 83% and NBC at 70.57%. This optimization approach may be used to improve the efficacy of community-based e-government services. | 2022-12-20T04:48:45.239Z |
14,701,539 | {
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"DOI": "10.1086/590141",
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"url": "http://arxiv.org/pdf/0802.1743"
} | Owing to its extremely high luminosity and long duration, supernova (SN) 2006gy radiated more energy in visual light than any other known SN. Two hypotheses to explain its high luminosity at early times—that it was powered by shock interaction with circumstellar material (CSM) as implied by its Type IIn spectrum, or that it was fueled by radioactive decay from a large mass of 56Ni synthesized in a pair-instability SN—predicted different late-time properties. Here we present observations of SN 2006gy obtained more than a year after discovery. We were unable to detect it at visual wavelengths, but clear near-infrared (IR) K′ and H-band detections show that it is still at least as luminous as the peak of a normal Type II SN. We also present spectra giving an upper limit to the late-time Hα luminosity of ≲1039 erg s−1. Based on the weak late-time Hα, X-ray, and radio emission, combined with the difficulty of explaining the shift to IR wavelengths, we can rule out ongoing CSM interaction as the primary late-time power source of SN 2006gy. Instead, we propose that the evolution of SN 2006gy is consistent with one of two possible scenarios: (1) a pair-instability SN plus modest CSM interaction, where the radioactive decay luminosity shifts to the IR because of dust formation; or (2) an IR echo, where radiation emitted during peak luminosity heats a pre-existing dust shell at radii near 1 light year, requiring the progenitor star to have ejected another shell of ~10 M☉ about 1500 yr before the SN. | 2022-12-29T15:41:17.377Z |
121,622,151 | {
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"DOI": "10.1139/P68-181",
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} | The results of observations, made during 1959–64, on intensity variations of EAS of mean sizes 1.4 × 104 to 1.4 × 105 particles at sea level are reported. Variations of shower size caused by fluctuations in pion decay have been observed and these correlate with density variations in the atmosphere. The corrected sidereal rate shows no evidence for anisotropy of the arrival directions of showers. | 2022-02-09T19:58:40.548Z |
220,889,474 | {
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"DOI": "10.1364/ol.395097",
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"license": "publisher-specific, author manuscript",
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"url": "https://doi.org/10.1364/ol.395097"
} | Widefield optical characterization of transparent samples is of great importance for gas flow and plasma diagnostics, for example, as well as label-free imaging of biological samples. An optically transparent medium, however, cannot be imaged by techniques based on intensity contrast imaging. Very well-known qualitative phase-contrast imaging methodologies are routinely used to overcome this limitation, and quantitative phase-imaging approaches have also been developed. Here we report the demonstration of, to the best of our knowledge, a novel widefield quantitative phase-imaging technique, based on fully common-path second-harmonic dispersion interferometry that is combined with pixel-by-pixel homodyne dual-channel polarization-dependent phase detection. The device is tested in a harsh environment reaching sub-10 mrad harmonic phase dispersion sensitivity and a spatial resolution of several tens of microns with an optical configuration that is very stable and easy to implement. The time resolution of the demonstrated device is 600 ps, set by the laser-pulse time duration. | 2022-09-23T00:58:06.230Z |
62,682,635 | {
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"DOI": "10.2307/2288457",
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} | From the Publisher:
The first systematic development of the principles and technology underlying the disguising of text and computer data. Formulates the principles underlying encipherment, analyzes a number of basic systems including the ``Enigma machine,'' and treats applications to data processing: public key systems, electronic signatures, communication and file security. | 2022-12-16T11:34:08.872Z |
255,050,363 | {
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"DOI": "10.55549/epstem.1219782",
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"url": "http://www.epstem.net/en/download/article-file/2834896"
} | <jats:p /> | 2022-12-24T21:23:15.533Z |
135,358,229 | {
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"DOI": "10.1111/ter.12377",
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},
"license": "CCBY",
"status": "HYBRID",
"url": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ter.12377"
} | Periadriatic Alpine magmatism has long been attributed to slab breakoff after Adria–Europe continental collision, but this interpretation is challenged by geophysical data suggesting the existence of a continuous slab. Here, we shed light on this issue based on a comprehensive dataset of zircon U–Pb ages and Hf isotopic compositions from the main western Periadriatic intrusives (from Traversella to Adamello). Our zircon U–Pb data provide the first evidence of Eocene magmatism in the Western Alps (42–41 Ma in Traversella), and demonstrate that magmatism started synchronously in different segments of the Alpine belt, when subduction was still active. Zircon U–Pb ages define younging trends perpendicular to the strike of the European slab, suggesting a progressive Eocene–Oligocene slab steepening. We propose that slab steepening enhanced the corner flow. This process was more effective near the torn edge of the European slab, and triggered Periadriatic magmatism in the absence of slab breakoff. | 2022-12-30T01:14:15.225Z |
180,786,397 | {
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"DOI": "10.5100/JJE.43.212",
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} | 本研究は, マルチディスプレイ型VDTの作業特性を明らかにし, ガイドラインや推奨事項を確立するための基礎資料を得ることを目的としている. 実験は10人の被験者を対象に編集作業とマウスポインティング作業をおのおの5分間, ディスプレイはシングル (1台), デュアル (2台) および大型の3条件について行われた. 評価は, 作業能率, 操作性, 頭部運動および頸部筋負担の四つの視点から行った.デュアルディスプレイおよびラージディスプレイは, シングルディスプレイよりも得られる情報量が多く, 操作がしやすいため作業能率が優れていることが示された. また頸部の筋負担はすべての実験条件で有意差が認められなかった. 特にデュアルディスプレイは, 画面が水平方向に広がるためラージディスプレイに比べて頭部運動が多く, 静的な筋負担を軽減する可能性が示唆された. | 2022-03-11T08:07:02.389Z |
247,934,527 | {
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"DOI": "10.21608/jssae.2005.225253",
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"url": "https://jssae.journals.ekb.eg/article_225253_d43a10c1482ce06221d70c727e82c27b.pdf"
} | A field experiment was conducted on a newly sandy loam soil at Dina Farm (Menofiya Governorate, Egypt) to study the effect of different levels of saline irrigation water, i.e., 400, 1500, 3000 and 4500 mg/l in the presence of combined rates of farmyard manure (FYM) and sulphur mixed with fertilizers (SMF) on growth parameters, yield, and elemental composition of barley plants ( Hordeum vulgare ) . Results indicated that , barley growth parameters and its yield showed a gradually significant decreases with increasing the salinity levels of irrigation water . Also,the NPK contents of barley straw and grains were decreased,while a pronounced increase was found for Na level .A parallel trend was noticed for micronutrients of Fe, Mn, Zn and Cu concentrations and uptake by barley straw and grains , also their values showed, in general, relatively decreases with the progressive levels of salts in irrigation water in treated and /or untreated soils with the used amendments . The interaction effects between the used amendments (combined FYM and SMF) and salinity levels of irrigation water showed a markedly increases for N , P, K , Fe, Mn and Zn contents,while Na exhibited a slightly decrease .It seems that the previously increases are largely depend on the used rate of FYM regardless the rates of SMF which appear their beneficial effects at rate of 0.5 ton /fed. supported by the highest rate of FYM (20 ton / fed.) specially under 3000 and 4500 mg /l salts in the irrigation waters. Generally, a similar trend was noticed for the nutrients uptake under consideration,as previously mentioned for their concentrations, parallel to the obtained trend of dry matter weights of both straw and grains yields . Moreover, applying the combined FYM and SMF led to decrease the hazardous effects of irrigation water salinity,consequently a favorable effect on enhanced the availability of macro and micronutrients for supporting growth and yield of barley plants grown on the studied newly sandy loam soils . | 2022-04-08T01:11:24.643Z |
150,156,580 | {
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"DOI": "10.32792/utq/utj/vol11/3/1",
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"url": "https://jutq.utq.edu.iq/index.php/main/article/download/68/61/"
} | The present study aimed to compare the effect of physical exercise in the morning and evening time on some physiological parameters which comprised from renal function test including blood urea nitrogen (BUN), serum creatinine (S.cr), some of serum electrolyte. (sodium and potassium) and blood pressure. The study included (20) males students volunteers of the second stage - College of Physical Education - University of Basra (10) students from the morning group and (10) students from the evening group. The results Showed that The Bun and S.cr concentration post-exercise in morning and evening group are significant higher than Pre-exercise in the same time, the Bun., S.cr concentration post-exercise in the evening group are higher than post-exercise in morning group (p≥0.05). But no significant (P≥0.05) in Sodium and Potassium . While the SYS and DIS blood Pressure level post-exercise are significant lower than Pre-exercise in the morning and evening group, and found that the SYS and DIS blood Pressure post-exercise in evening group are lower In comparison with post-exercise in morning group (p≥0.05).
Conclusion: The physical exercise cause significantly higher in Bun and S.cr, the concentration of Bun and S.cr post-exercise in evening time are higher than post-exercise in morning time, no significant was appeared in sodium and potassium levels. Conversely, significantly lower in SYS and DIS blood Pressure post-exercise.While, SYS and DIS blood Pressure post-exercise in evening time are significant lower In comparison with post-exercise in morning time | 2022-08-27T04:49:20.406Z |
8,436,208 | {
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"DOI": "10.1364/OE.15.004893",
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} | The effective nonlinear coefficient and temperature acceptance bandwidth of three Lu and Sc co-doped GdCa(4)O(BO(3))(3) type nonlinear crystals were measured. NCPM for SHG in to the blue-UV spectral region can be obtained by controlling the co-dopant concentration. Measurements were based on intra-cavity SHG of a CW Ti:Sapphire laser, and the effective nonlinear coefficients were found to be in the range of 0.5 to 0.6 pm/V for the three crystals used. The FWHM temperature acceptance bandwidth was measured to be more than 35 degrees C using a 6 mm long Gd(0.871)Lu(0.129)Ca(4)O(BO(3))(3) crystal. A maximum of 115 mW at 407.3 nm in a single direction was measured using a 6.5 mm long Gd0.96Sc0.04Ca(4)O(BO(3))(3) crystal. | 2022-08-29T11:25:18.481Z |
145,254,573 | {
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"DOI": "10.1207/s15328023top0602_11",
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} | Description and evaluation of a course that intelligently and personally delves into a pervasive form of student behavior. | 2022-09-15T09:21:06.366Z |
10,683,390 | {
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"DOI": "10.3348/kjr.2011.12.3.341",
"MAG": "2787290256",
"PubMedCentral": "3088851"
},
"license": "CCBYNC",
"status": "GREEN",
"url": "https://europepmc.org/articles/pmc3088851?pdf=render"
} | Objective We wanted to validate the additional merit of the thinner coronal reformation images from multidetector CT (MDCT) for making the diagnosis of hepatic cysts. Materials and Methods For the 90 benign hepatic cysts confirmed on MRI, the transverse (5-mm thickness) and additional coronal (2-mm thickness) reformation images from MDCT were compared with each other in terms of the Hounsfield units (HUs) and the size of each hepatic cyst. Results The attenuations (mean: 17.2 HUs, standard deviation: ± 14.4) on the thinner coronal images were significantly lower than those (mean: 40.7 HUs; standard deviation: ± 20.6) on the thicker transverse images for the small hepatic cysts (≤ 10 mm on the transverse image, p < 0.01). Twenty-three (79%) of the 29 cysts between 5 mm and 10 mm and 21 (51%) of 41 lesions up to 5 mm showed a mean HU value of 20 or less on the coronal reformation images. Conclusion By reducing the partial volume effect, routine coronal reformation of MDCT with a thinner section thickness can provide another merit for making a confidential diagnosis of many small sub-centimeter hepatic cysts, and these small cysts are not easily characterized on the conventional transverse images. | 2022-12-09T05:17:23.568Z |
150,022,204 | {
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} | INTRODUCTION AND OBJECTIVES: Benign ureteric strictures are commonly encountered in daily practice. Severe strictures are managed by various forms of reconstructive surgery. Mild to moderate strictures can be managed endoscopically. However, balloon dilatation of benign ureteric strictures has not been widely practiced due to lack of long-term data. We would like to present the outcome of our series and examine the risk factors of stricture recurrence. METHODS: There were 111 strictures (in 101 patients) in our prospectively maintained database since August 2012 to July 2018. The strictures were dilated retrogradely or antegradely using Reef HP or Olympus EZDilate balloon catheters. They were serially dilated until a mean maximal pressure of 16.8 atm (SD±3.6). This was followed by a check ureteroscopy and retrograde pyelogram in the retrograde dilatation group. In the antegrade group, a check nephrostogram was done. A DJ stent was inserted in every patient at the end of procedure. A follow up IVU, CT or nephrostogram was performed to check for recurrence. RESULTS: Mean age of patients was 57.7 years old (SD±12.6). There were 109 ureteric and 2 ureteroileal anastomotic benign strictures. Mean length of strictures was 11.0mm (SD±8.6). Mean duration of DJ stent placement was 5.5 weeks (SD±3.7). Mean follow up was 20.2 months (SD±17.4). The overall stricture patency rate is shown in the table below. There was no intraoperative ureteric injury/avulsion that required immediate or delayed reconstruction. Only 12 patients (10.8%) had to undergo reconstructive surgery or to be on long term nephrostomy tube (if unfit for surgery). Strictures caused by radiotherapy was at 100% (5/5) risk of recurrence, iatrogenic injury 66.7% (8/12) and stone/inflammation 28.0% (21/75), p = 0.000. Strictures detected on preoperative imaging also had significantly higher risk of recurrence at 58.3% (28/48) vs incidental strictures at 13.6% (6/44), p = 0.000. Strictures associated with atrophic kidney had recurrence rate of 72.2% (13/18) vs normal kidney 28.4% (21/74), p = 0.001. The mean length of strictures was 12.5 mm (SE±1.7) in the recurrence group vs 9.6 mm (SE±0.7) in those without recurrence, p = 0.001. There were no significant differences in the location of stricture and severity of hydronephrosis. The incidental stricture patency rate is shown in the table below. CONCLUSIONS: Endoscopic balloon dilatation of benign ureteric stricture is a feasible option. Its effect can be long lasting in carefully selected patients i.e. non radiated, incidental, short strictures with normal kidneys; or those not fit for reconstructive surgery. Table. No title available. Source of Funding: none | 2022-02-09T04:05:00.737Z |
212,923,931 | {
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"DOI": "10.2966/SCRIP.170120.4",
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} | Due to the increased complexity of new technologies and rapid technological developments, organisations often cannot independently keep up with the technological progress and engage in open innovation activities by setting up R&D partnerships. The allocation of patent ownership of jointly developed inventions is a difficult issue during the negotiations of such partnerships and can be extremely problematic due to the lack of regulation and harmonisation of patent legislation. This entails the need to consult a considerable number of legal systems that may be involved in large-scale international partnerships. The difficulties in allocating ownership can also arise due to non-legal reasons, such as diverging business interests. While many patent systems suggest coownership as a default regime, in practice organisations often avoid it due to the complexity related to further joint exploitation. The principle of freedom of contract allows organisations to establish their own applicable rules governing the allocation of ownership and exploitation of jointly developed inventions. Those rules provide more flexibility, but also imply some transaction costs in designing contracts. In this paper I examine why (2020) 17:1 SCRIPTed 4 5 certain default rules are not “sticky” and whether it would be possible to establish a default rule accepted by the majority of the negotiating parties. | 2022-02-18T00:42:48.475Z |
55,762,624 | {
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"DOI": "10.5205/1981-8963-v10i4a11116p1292-1298-2016",
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} | ABSTRACT Objective: to evaluate the efficacy of screening tests for HPV lesions of the cervix. Method: this is a descriptive and exploratory study of a quantitative approach, developed in the municipal outpatient in Brejinho/PE, with 50 women. Data collection was carried out in July 2015, with a questionnaire and then analyzed with descriptive statistics. Results: participants were married women with a middle educational level, the majority lives with husband; much does not use condoms and know the importance of having a cervical smear test annually. Conclusion: the incidence of cervical cancer is relatively low, taking into account the statistical data of research compared to other studies regarding the risk factors for development of cancer and the importance of nursing in the guidelines regarding the Pap smear. Descriptors: Human Papilloma Virus; Women; Cervical Cancer. RESUMO Objetivo : avaliar a eficacia dos exames de rastreamento das lesoes HPV do colo uterino. Metodo : estudo exploratorio-descritivo, com abordagem quantitativa, desenvolvido no ambulatorio municipal de Brejinho/PE, com 50 mulheres. A coleta de dados foi realizada em julho de 2015, com um questionario, em seguida, analisados pela estatistica descritiva. Resultados : participaram desse estudo mulheres casadas e com grau de escolaridade mediana, a maioria vive com esposo, grande parte nao faz uso de preservativo e conhecem a importância da realizacao do exame preventivo anualmente. Conclusao : a incidencia de casos de câncer de colo uterino e relativamente baixa, levando em consideracao os dados estatisticos da pesquisa comparados a outros estudos, no que tange fatores de risco para desenvolvimento do câncer e a importância da enfermagem nas orientacoes a respeito do exame Papanicolau . Descritores : Papiloma Virus Humano; Mulheres; Câncer de Colo de Utero. RESUMEN Objetivo: evaluar la eficacia de los testes de deteccion de las lesiones del VPH del cuello uterino. Metodo: este es un estudio exploratorio y descriptivo con un enfoque cuantitativo, desarrollado en el ambulatorio municipal de Brejinho/PE, con 50 mujeres. La recoleccion de datos se llevo a cabo en julio de 2015, con un cuestionario, despues se analizaron mediante la estadistica descriptiva. Resultados: los participantes eran mujeres casadas con la calidad de educacion media, la mayoria vive con su marido, gran parte no usa condones y conoce la importancia de hacer testes preventivos anualmente. Conclusion: la incidencia de casos de cancer de cuello uterino es relativamente baja, teniendo en cuenta los datos estadisticos de la investigacion en comparacion con otros estudios acerca de los factores de riesgo de desarrollo de cancer y la importancia de la enfermeria en las directrices relativas a la prueba de Papanicolaou. Descriptores: Virus del Papiloma Humano; Las Mujeres; Cancer de Cuello del Utero. Normal 0 21 false false false PT-BR X-NONE X-NONE /* Style Definitions */
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40,619,294 | {
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"DOI": "10.22037/IJCN.V11I3.10528",
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} | Hyperhomocysteinemia can cause cerebral venous thrombosis. Recombinant tissue plasminogen activator is one of the treatment options for cerebral venous thrombosis in selected cases. We present here a 7-year-old boy with homocysteinuria with stroke. MRI of brain showed cerebral venous sinus thrombosis. We successfully treated with intravenous recombinant tissue plasminogen activator. He recovered completely without any complications. Recombinant tissue plasminogen activator can be considered one of the treatment options in cerebral venous thrombosis in homocystinura. | 2022-08-20T21:03:59.332Z |
45,767,008 | {
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"DOI": "10.1001/archopht.1931.00820070725005",
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"url": "http://europepmc.org/articles/pmc1316795?pdf=render"
} | The long ciliary nerves accompany the long posterior ciliary arteries through their emissaries in the posterior part of the sclera, each nerve dividing into two branches before emerging into the suprachoroidal space. These four nerves course forward in a meridional direction between the sclera and the choroid. Sometimes near the junction of the orbiculus ciliaris and the corona ciliaris, or from 2.5 to 3 mm. from the angle of the anterior chamber, the ciliary nerve enters the sclera and then turns abruptly back again to resume its forward course into the ciliary body. Occasionally the nerve loop thus formed extends through the entire thickness of the sclera with its cupola projecting above the external scleral surface, covered only by conjunctiva. This nerve loop may extend into the sclera perpendicular to, or at an angle with, the surface, or it may be retroverted or anteflexed. Its apex is sometimes mushroom-shaped, due | 2022-09-06T18:17:40.068Z |
220,239,214 | {
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"DOI": "10.1136/bmj.2.3386.976",
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} | selected hlis specialist, often w;-ithout reference to a general practitioner at all. Sle dealt also with the more obvious defects of medical education, stressing the fact that the newly qualified student, althougli well equipped to recognize and treat rare and urgent cases, had little or no knowledge of the commoner anid slighter forms of disease. Dr. Murrell's remarks were in the niature of a challenge to discussioni, and a lively argumenit ensued, among the sl)eakers being Mrs. Flemmiing, Mrs. Burney, Dr. Casson, Dr. Fairfield, Dr. Dobie, Mrs. Gordon Holmes. | 2022-01-24T22:07:24.245Z |
220,018,858 | {
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"DOI": "10.1136/annrheumdis-2019-eular.1993",
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} | Background In 2006 the curriculum for rheumatology health professionals of the Academy of the German Association of Rheumatologists (DGRh) was developed. [1]. Since then more than 1400 health professionals (medical assistants [medizinische Fachangestellte] and nurses) were trained and are currently playing an increasing role in rheumatology practices in Germany. Objectives To evaluate the patients’ opinion on the assessment by medical assistants in general and regarding assessment and education on cardiovascular risk and vaccination. Methods Patients with rheumatoid arthritis were interviewed by a medical assistant in a rheumatology practice that is part of the public health care system with five rheumatologists in Erlangen, Germany A semi-standardized interview assessed disease activity, pain, medication, general health, and side effects of medication. A part of the patients was also assessed and educated regarding cardiovascular risk or vaccinations. Thereafter they were examined by the rheumatologist and finally asked to complete a questionnaire regarding their visit. The questions were numerical scales ranging from 0 [very good, very satisfied] to 10 [very poor/inadequate]. Results 293 Patients (mean age 61.3 ± 13.5 years, mean DAS28 2.8 ± 0.9, mean FFbH 76,4 ± 20.8) were documented between August and December 2018. 212 completed the general questionnaire, 34 regarding a structured cardiovascular assessment and education, and 18 regarding a structured assessment of vaccinations. Table 1 shows patients answers between 0 [very good, very satisfied] to 10 [very poor/inadequate]. Overall rating was excellent with a mean score of 1.0 (SD 1.5). The rating was only slightly different, if patients were assessed by medical assistants for the first time (n=111; mean score 1.2, SD 1.5), between the 2nd to 4th time (n=82; mean score 1.0, SD 1.3) or the 5th time or more (n=19; mean score 0.6, SD 0.6) Mean (0= very good/very satisfied; 10= very poor/inadequate) SD General questions The prior consultation to a medical assistant is estimated as ? 0= good – 10 = bad 1.04 1.66 Regarding acquiring information and asking questions the form of consultation is ? 0 = better – 10 = worse 1.28 1.76 All of my questions were answered0 = correct – 10 = incorrect. 0.89 1.55 The further consultation to the physician was ? 0 = adequate – 10 - inadequate 0.96 1.49 Cardiovascular assessment and education I was able to understand the information. 0 = correct – 10 = incorrect 0.50 0.96 I had the opportunity to ask questions. 0 = correct – 10 = incorrect 0.50 0.90 The information was helpful, I learned something new. 0 = correct – 10 = incorrect 1.32 1.93 I am planning to put the information into practice. 0 = correct – 10 = incorrect 0.74 0.86 Information on vaccination I was able to understand the information. 0 = correct – 10 = incorrect 0.17 0.38 I had the opportunity to ask questions. 0 = correct – 10 = incorrect 0.22 0.43 The information was helpful, I learned something new. 0 = correct – 10 = incorrect 1.06 1.35 I am planning to put the information into practice. 0 = correct – 10 = incorrect 0.44 0.78 Conclusion The semi-standardized assessment of patients with rheumatoid arthritis by medical assistants, the cardiovascular risk assessment and education, and the assessment and information on vaccination was very well accepted and appreciated by patients. Currently, there is no reimbursement by the German health care system. Reference [1] Schuch F, Kern P, Kreher G, Kruger K, Wendler J, Fiehn C. [Curriculum for “Rheumatology health professionals DGRh-BDRh” as a way of qualification for clinical nursing specialists : Concept and results of an evaluation]. Z Rheumatol. 2011 Oct; 70(8):670-677. Acknowledgement Statistical analysis was carried out by Dr. M. Englbrecht, Healthcare Data Scientist, Eckental, Germany. Disclosure of Interests Stefan Kleinert Grant/research support from: Novartis, Consultant for: Novartis, UCB, Chugai, Celgene, Medac, Roche, Abbvie, Speakers bureau: Novartis, UCB, Chugai, Celgene, Medac, Roche, Abbvie, Praxedis Rapp: None declared, Monika Ronneberger Consultant for: Celgene, Novartis, Paid instructor for: Abbvie, Bristol Myers Squibb, Novartis, Speakers bureau: Celgene, Novartis, Bristol Myers Squibb, Pfizer, Joerg Wendler Consultant for: Roche Pharma AG, AbbVie, Jannssen Cilag, Novartis, Speakers bureau: Roche Pharma AG, AbbVie, Jannssen Cilag, Novartis, Florian Schuch Consultant for: Celgene, Lilly, UCB, Roche, Sanofi-Aventis, Abbvie, Novartis, Speakers bureau: Celgene, Lilly, UCB, Roche, Sanofi-Aventis, Abbvie | 2022-01-27T19:08:43.613Z |
237,599,820 | {
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"DOI": "10.1109/ICEAA52647.2021.9539608",
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} | To aim to achieve portable, low power consumption, low cost and green high performance computation (HPC) for electromagnetic field simulation, we have been investigating a method of dedicated computer based on dataflow architecture. To construct the computer architecture dedicated to the target applications, overhead of unnecessary process such as data transfer between CPU and memories are avoided and extremely efficient computer processing with highly parallel computation can be achieved. Indeed, it was shown that the dedicated computer with the dataflow architecture executed simulation of electromagnetic wave effectively[1]. | 2022-01-24T22:20:16.184Z |
15,720,333 | {
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"DOI": "10.1109/IROS.2004.1389875",
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} | This paper presents the formalism of statistical snakes for contour estimation, and applies it to the problem of tracking a natural benthic contour using an AUV equipped with a video camera. To close the control loop that maintains the vehicle on the contour, we need to estimate its location on each frame of the video sequence. We propose a new criterion for contour estimation which is appropriate to the complexity and variability of natural environments. The criterion is based on a non-parametric statistical modeling of the regions adjacent to the tracked boundary, as mixtures of the probability distributions corresponding to the areas on each side of the contour. It is shown on the paper that minimizing the proposed criterion leads to an estimated contour such that the regions on each side have mixture coefficients close to zero and one (meaning that they are "pure" regions). Examples of application of the proposed algorithm to a real underwater image sequence are given. | 2022-09-09T01:03:51.474Z |
209,285,520 | {
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"DOI": "10.1097/CCE.0000000000000061",
"MAG": "2984177119",
"PubMedCentral": "7063962"
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} | Objectives: This review will examine current definitions and trends in sepsis management as well pathophysiologic mechanisms in animal and ex vivo studies that correlate decreased energy production with deranged inflammatory response during the septic process. Data Sources: The latest articles in the literature that focus on the role of immunometabolism and associated mechanisms in sepsis were selected. Study Selection: The most relevant, original articles were included in the review. Data Extraction: All pertinent data for sepsis definitions as well as changes in immunometabolic pathways during the septic process was reviewed and assessed for inclusion in this article. Data Synthesis: Sepsis is a major cause of multiple organ dysfunction. It is the principal cause of death resulting from infection and one of the most expensive conditions treated in the United States. Despite current efforts to accurately define sepsis, novel treatments and highly trained providers, mortality rates for sepsis remain high, prompting a need for further investigation of underlying immunometabolic mechanisms to identify potential treatment targets. The definition of sepsis has shifted and changed in the past few decades due to poorly defined criteria, as well as unclear guidelines for providers with regards to management of severe sepsis and septic shock. The early identification of patients with a systemic inflammatory response that will progress to septic shock is critical since recent traditional therapeutic approaches, such as early goal-directed therapy, IV immunoglobulin, and anti–tumor necrosis factor-α antibodies have failed. Conclusions: There are no effective anti-sepsis drug therapies due to complex inflammatory and metabolic interactions. Further studies regarding the interface between innate immunity and metabolism should be investigated to effectively address septic patient mortality rates. | 2022-11-24T07:09:43.136Z |
48,539,833 | {
"externalids": {
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"ArXiv": null,
"DOI": "10.18000/IJODAM.70020",
"MAG": "2277811945",
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} | An overview is given on the state of art of the laser based surface processing of engineering materials. In major engineering application surface of the material plays a major role. since the surface has the direct contact with the environment as well as the load. The different parameters such as hardness, toughness, wear resistance etc on the surface has to be enhanced based on the application, hence there is a need to go for surface processing. Conventional surface processing has its own limitations toward recently developed materials and other functional aspects. These aspects can be overcome by laser based surface processing. In this paper an attempt has been made to investigate the principal and effect of laser interaction on materials such as heating, surface melting, vaporization, plasma formation , ablation etc .The different types of laser based surface processing of engineering materials based on their properties, Processing parameters and functional aspects which is considered for different application has been discussed. | 2022-08-25T00:10:53.373Z |
83,850,306 | {
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"DOI": "10.21273/HORTSCI.29.7.762",
"MAG": "1807632985",
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"url": null
} | What is a transgenic plant? Why create disease-resistant transgenic plants? State-of-the-art : transformation methodology, genes for transfer, examples. Designing the future: postharvest problems, developing postharvest disease-resistant transgenic plants. Concluding remarks: problems to overcome, integrated disease management strategies, safety, philosophy | 2022-09-11T04:57:18.601Z |
244,537,905 | {
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"DOI": "10.3390/cryst11121434",
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},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/2073-4352/11/12/1434/pdf?version=1637807221"
} | This experimental study presents concrete-filled double-skin tubular columns and demonstrates their expected advantages. These columns consist of an outer steel tube, an inner steel tube, and concrete sandwiched between two tubes. The influence of the outer-to-inner tube dimension ratio, outer tube to thickness ratio, and type of inner tube material (steel, PVC pipe) on the ultimate axial capacity of concrete-filled double-skin tubular columns is studied. It is found that the yield strength of the inner tube does not significantly affect the ultimate axial capacity of concrete-filled double-skin tubular composites. With the replacement of the inner tube of steel with a PVC pipe, on average, less than 10% strength is reduced, irrespective of size and dimensions of the steel tube. Hence, the cost of a project can be reduced by replacing inner steel tubes with a PVC pipes. Finally, the experimental results are compared with the existing design methods presented in AISC 360-16 (2016), GB51367 (2019), and EC4 (2004). It is found from the comparison that GB51367 (2019) gives better results, followed by AISC (2016) and EC4 (2004). | 2022-11-27T18:21:35.632Z |
96,788,856 | {
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"DOI": "10.1107/S0021889883010262",
"MAG": "2099321807",
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} | A new and accurate method has been developed by which all the components of the anisotropy of the optical susceptibilities can be determined. The apparatus based on this method has been constructed, and named as HAUP (High-Accuracy Universal Polarimeter). The basic principle is to measure the intensity of the light beam, which is propagated successively through a polarizer, a specimen, and an analyser, as functions of azimuth and deflecting angle from the crossed-Nicols condition. Thus the method is characterized by its extreme simplicity, which prevents systematic errors. Considerations and tests of inevitable systematic errors are made. The systematic errors originating in the parasitic ellipticities of the polarizer and analyser are found to be serious for the measurements of optical activity; appropriate solutions to remove them are devised here. Sensitivities of measurements of optical activity and birefringence by the HAUP method reach 4.8 × 10−8 and 2.2 × 10−6 respectively, the accuracy being 4.2 × 10−3 and 2.2 × 10−3 respectively. By using HAUP it has become possible to measure simultaneously all the components of optical activity, birefringence and rotation of optical indicatrix of any crystals, including those belonging to the monoclinic and triclinic systems. These measurements can be made from about 400 K down to 10 K. Also, simultaneous determinations of electrogyration and electrooptic coefficients have become feasible by applying electric fields to crystals. | 2022-12-15T01:10:46.082Z |
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