text
stringlengths 57
1.72k
| relation
stringclasses 125
values | h
dict | t
dict |
|---|---|---|---|
the role of hormones has been discussed with the framework of the secretin-glucagon family , the cholecystokinin-gastrin family , and other proposed gastrointestinal hormones and related peptides . | NA | {
"id": "C0019932",
"name": "hormones",
"pos": [
12,
20
]
} | {
"id": "C0017182",
"name": "gastrointestinal hormones",
"pos": [
149,
174
]
} |
the role of hormones has been discussed with the framework of the secretin-glucagon family , the cholecystokinin-gastrin family , and other proposed gastrointestinal hormones and related peptides . | NA | {
"id": "C0036534",
"name": "secretin",
"pos": [
66,
74
]
} | {
"id": "C0017182",
"name": "gastrointestinal hormones",
"pos": [
149,
174
]
} |
the role of hormones has been discussed with the framework of the secretin-glucagon family , the cholecystokinin-gastrin family , and other proposed gastrointestinal hormones and related peptides . | NA | {
"id": "C0008328",
"name": "cholecystokinin",
"pos": [
97,
112
]
} | {
"id": "C0017182",
"name": "gastrointestinal hormones",
"pos": [
149,
174
]
} |
the role of hormones has been discussed with the framework of the secretin-glucagon family , the cholecystokinin-gastrin family , and other proposed gastrointestinal hormones and related peptides . | NA | {
"id": "C0017151",
"name": "gastrin",
"pos": [
113,
120
]
} | {
"id": "C0017182",
"name": "gastrointestinal hormones",
"pos": [
149,
174
]
} |
[ salivary gland diseases . clinical picture , diagnosis . part 2. inflammation of the salivary glands ( sialadenitides , cont . ) , sjogren 's syndrome , special forms , sialadenoses ] . | NA | {
"id": "C0036093",
"name": "salivary gland diseases",
"pos": [
2,
25
]
} | {
"id": "C0037023",
"name": "sialadenitides",
"pos": [
105,
119
]
} |
it could be shown that beside the non-absorbable synthetic suture material ( polypropylene ) for the subcuticular continuous skin suture absorbable synthetic suture material ( polyglactin 910 ) is suitable for the buried subcuticular skin suture to obtain good esthetic scars in plastic surgery . | NA | {
"id": "C0032582",
"name": "polypropylene",
"pos": [
77,
90
]
} | {
"id": "C0032167",
"name": "plastic",
"pos": [
279,
286
]
} |
hexoses and pentoses , but not tetroses or trioses , are potent inhibitors of the increase in vascular permeability in rat skin produced by the polysaccharides -- dextran , mannan and glucan . | NA | {
"id": "C0032594",
"name": "polysaccharides",
"pos": [
144,
159
]
} | {
"id": "C0024727",
"name": "mannan",
"pos": [
173,
179
]
} |
antibodies of various immunoglobulin classes against cow 's milk proteins were studied in infants and children with cow 's milk protein intolerance , gluten-sensitive enteropathy and acute gastroenteritis . | NA | {
"id": "C0003241",
"name": "antibodies",
"pos": [
0,
10
]
} | {
"id": "C0021017",
"name": "immunoglobulin classes",
"pos": [
22,
44
]
} |
by combining the findings of antibody increases in various immunoglobulin classes , an individual discrimination could be reached . | NA | {
"id": "C0003241",
"name": "antibody",
"pos": [
29,
37
]
} | {
"id": "C0021017",
"name": "immunoglobulin",
"pos": [
59,
73
]
} |
incubation at 40 degrees for 1 h did not destory the tmv rna replicase , because viral rna synthesis resumed upon return to 25 degrees . | NA | {
"id": "C0035668",
"name": "rna",
"pos": [
57,
60
]
} | {
"id": "C0035736",
"name": "viral rna",
"pos": [
81,
90
]
} |
sections of ovary from plains viscacha , cat , ferret , rabbit , rat , guinea-pig and roe deer have been histochemically processed to demonstrate acetylcholinesterase ( ache ) and butyrylcholinesterase ( buche ) in nervous and non-nervous tissue . | NA | {
"id": "C0001044",
"name": "acetylcholinesterase",
"pos": [
146,
166
]
} | {
"id": "C0008429",
"name": "butyrylcholinesterase",
"pos": [
180,
201
]
} |
no other species showed a reaction for ache in non-neuronal stromal tissue but buche was present at this site in all animals except rat . | NA | {
"id": "C0001044",
"name": "ache",
"pos": [
39,
43
]
} | {
"id": "C0008429",
"name": "buche",
"pos": [
79,
84
]
} |
by contrast , consideration of the over-all balance of protein metabolism in these cells indicates that the average concentration of metabolically turning-over proteins is somewhat higher in senescent than in young fibroblasts . | NA | {
"id": "C0007634",
"name": "cells",
"pos": [
83,
88
]
} | {
"id": "C0016030",
"name": "fibroblasts",
"pos": [
215,
226
]
} |
ribonucleotide reduction was measured in chinese hamster ovary cells made permeable to nucleotides by treatment with the detergent tween-80 . | NA | {
"id": "C0035548",
"name": "ribonucleotide",
"pos": [
0,
14
]
} | {
"id": "C0028630",
"name": "nucleotides",
"pos": [
87,
98
]
} |
transformation of chicken embryo fibroblasts with rous sarcoma virus results in cells with an enhanced rate of hexose uptake . | NA | {
"id": "C0016030",
"name": "fibroblasts",
"pos": [
33,
44
]
} | {
"id": "C0007634",
"name": "cells",
"pos": [
80,
85
]
} |
scatchard plots on two of these clones , one epithelioid and one fibroblastic , showed that the higher egf binding ( 1.3 x 10 ( 5 ) molecules per cell for the epithelioid clone and 1.3 x 10 ( 4 ) molecules per cell for the fibroblastic clone ) was due to a greater number or receptors on the epithelioid cells rather than to a difference in the apparent affinity constant . | NA | {
"id": "C0007634",
"name": "cell",
"pos": [
146,
150
]
} | {
"id": "C0016030",
"name": "fibroblastic",
"pos": [
223,
235
]
} |
rapid procedure for chromatographic isolation of dopa , dopac , epinephrine , norepinephrine and dopamine from a single urinary sample at endogenous levels . | NA | {
"id": "C0014563",
"name": "epinephrine",
"pos": [
64,
75
]
} | {
"id": "C0028351",
"name": "norepinephrine",
"pos": [
78,
92
]
} |
a three-step procedure has been investigated to extract 3,4-dihydroxyphenylalanine ( dopa ) , 3,4-dihydroxyphenylacetic acid ( dopac ) , epinephrine ( e ) , norepinephrine ( ne ) and dopamine ( da ) from a single urinary sample with the object of obtaining extracts pure enough for specific fluorimetric assay . | NA | {
"id": "C0014563",
"name": "epinephrine",
"pos": [
137,
148
]
} | {
"id": "C0028351",
"name": "norepinephrine",
"pos": [
157,
171
]
} |
the procedure described in this paper results from the combination of urine purification on an aluminum oxide column , separation by ion-exchange chromatography of the dopa-dopac fraction from catecholamines , and ether isolation of dopac from dopa . | NA | {
"id": "C0007412",
"name": "catecholamines",
"pos": [
193,
207
]
} | {
"id": "C0013023",
"name": "dopa",
"pos": [
244,
248
]
} |
the time course of the concentration of salicylic acid in serum is demonstrated after oral administration of 1 g sodium-salicylate . | NA | {
"id": "C0036079",
"name": "salicylic acid",
"pos": [
40,
54
]
} | {
"id": "C0037549",
"name": "sodium-salicylate",
"pos": [
113,
130
]
} |
thin-layer chromatographic method for determination of diazepam and its major metabolite , n-desmethyldiazepam , in human serum . | NA | {
"id": "C0012010",
"name": "diazepam",
"pos": [
55,
63
]
} | {
"id": "C0011279",
"name": "desmethyldiazepam",
"pos": [
93,
110
]
} |
in order to investigate the magnitude and kinetics of the c-reactive protein ( crp ) response after differing degrees of tissue injury , we studied changes in serum concentration of this acute phase protein in 19 patients after mild or extensive acute myocardial infarction . | NA | {
"id": "C0006560",
"name": "c-reactive protein",
"pos": [
58,
76
]
} | {
"id": "C0001347",
"name": "acute phase protein",
"pos": [
187,
206
]
} |
when compared to lean , nondiabetic db+/m+ or m+/m+ mice , db+/db+ mice demonstrated markedly altered in vivo immune responses characterized by a significantly diminished ability to reject allogeneic skin grafts , a markedly diminished capacity to generate cytotoxic cells after sensitization with allogeneic el-4 lymphoma cells and a significantly enhanced plaque-forming cell response to sheep erythrocytes . | NA | {
"id": "C3485979",
"name": "allogeneic",
"pos": [
189,
199
]
} | {
"id": "C0007634",
"name": "cell",
"pos": [
373,
377
]
} |
in contrast , spleen cells from db+/db+ mice demonstrated only minimal alterations in in vitro responses to mitogens and allogeneic cells and no alteration in their capacity to generate an in vitro plaque-forming cell response . | NA | {
"id": "C3485979",
"name": "allogeneic cells",
"pos": [
121,
137
]
} | {
"id": "C0007634",
"name": "cell",
"pos": [
213,
217
]
} |
a progressive decrease of platelet count ( to 60 % of the predisease state ) , functional prekallikrein ( 55 % ) and kallikrein inhibitor ( 47 % ) with a nadir reached on day 5 of the fever and a subsequent overshoot during convalescence . | NA | {
"id": "C0033024",
"name": "prekallikrein",
"pos": [
90,
103
]
} | {
"id": "C0022478",
"name": "kallikrein",
"pos": [
117,
127
]
} |
despite the drop in functional prekallikrein and kallikrein inhibitor , there was no change in factor xii clotting activity or antigenic concentrations of prekallikrein and the kallikrein inhibitors , c1 esterase inhibitor ( c1-inh ) and alpha ( 2 ) -macroglobulin . | NA | {
"id": "C0022478",
"name": "kallikrein",
"pos": [
34,
44
]
} | {
"id": "C0033024",
"name": "prekallikrein",
"pos": [
155,
168
]
} |
the finding of a reduction in functional prekallikrein and kallikrein inhibitor ( c1-inh ) and the formation of a kallikrein c1-inh complex is consistent with prekallikrein activation in typhoid fever . | NA | {
"id": "C0022478",
"name": "kallikrein",
"pos": [
44,
54
]
} | {
"id": "C0033024",
"name": "prekallikrein",
"pos": [
159,
172
]
} |
these findings show that the basic defect in type iii hyperlipoproteinemia is qualitatively different from the cellular defect found in familial hypercholesterolemia , since the regulation of hmg-coa reductase activity is normal in type iii fibroblasts . | NA | {
"id": "C0007634",
"name": "cellular",
"pos": [
111,
119
]
} | {
"id": "C0016030",
"name": "fibroblasts",
"pos": [
241,
252
]
} |
the saa response showed a similar time response to c-reactive protein ( crp ) , a well-documented acute phase protein which was assayed semiquantitatively by capillary tube precipitin reaction . | NA | {
"id": "C0002723",
"name": "saa",
"pos": [
4,
7
]
} | {
"id": "C0001347",
"name": "acute phase protein",
"pos": [
98,
117
]
} |
the saa response showed a similar time response to c-reactive protein ( crp ) , a well-documented acute phase protein which was assayed semiquantitatively by capillary tube precipitin reaction . | NA | {
"id": "C0006560",
"name": "c-reactive protein",
"pos": [
51,
69
]
} | {
"id": "C0001347",
"name": "acute phase protein",
"pos": [
98,
117
]
} |
catecholamine agonists compete for occupancy of the [ ( 3 ) h ] dihydroergocryptine binding sites with an order of potency ( - ) epinephrine > ( - ) norepinephrine > > ( - ) isoproterenol . | NA | {
"id": "C0007412",
"name": "catecholamine",
"pos": [
0,
13
]
} | {
"id": "C0022245",
"name": "isoproterenol",
"pos": [
174,
187
]
} |
catecholamine agonists compete for occupancy of the [ ( 3 ) h ] dihydroergocryptine binding sites with an order of potency ( - ) epinephrine > ( - ) norepinephrine > > ( - ) isoproterenol . | NA | {
"id": "C0014563",
"name": "epinephrine",
"pos": [
129,
140
]
} | {
"id": "C0028351",
"name": "norepinephrine",
"pos": [
149,
163
]
} |
stereospecificity was demonstrated inasmuch as the ( + ) isomers of epinephrine and norepinephrine were 10-20-fold less potent than the ( - ) isomers . | NA | {
"id": "C0014563",
"name": "epinephrine",
"pos": [
68,
79
]
} | {
"id": "C0028351",
"name": "norepinephrine",
"pos": [
84,
98
]
} |
to explore the etiology of congenital hypoplastic anemia ( cha ) or the diamond-blackfan anemia , erythropoietin responsive committed erythroid precursors were enumerated by the plasma clot method . | NA | {
"id": "C0949116",
"name": "congenital hypoplastic anemia",
"pos": [
27,
56
]
} | {
"id": "C1260899",
"name": "diamond-blackfan anemia",
"pos": [
72,
95
]
} |
growth was evaluated in a group of 10 infants and children with familial or idiopathic classic renal tubular acidosis in whom alkali therapy was initiated at ages ranging from 8 days to 9.5 yr and administered at dosage schedules documented to sustain correction of acidosis in at least four prolonged observation periods on the pediatric clinical research ward . | NA | {
"id": "C0001126",
"name": "renal tubular acidosis",
"pos": [
95,
117
]
} | {
"id": "C0001122",
"name": "acidosis",
"pos": [
266,
274
]
} |
the combination of iabp and surgery has resulted in survival of approximately 50 per cent of patients in cardiogenic shock secondary either to a mechanical defect complicating myocardial infarction or to open-heart surgery . | NA | {
"id": "C0036980",
"name": "cardiogenic shock",
"pos": [
105,
122
]
} | {
"id": "C0027051",
"name": "myocardial infarction",
"pos": [
176,
197
]
} |
special attention was payed to four types of catecholamine infusions during which the highest cardiac index ( ci ) , 161-168 % of control , was seen : dopamine 500 mcg/min ( d 500 ) , epinephrine 8 mcg/min ( e 8 ) , dopamine 250 mcg/min combined with epinephrine 4 mcg/min ( d 250 + e4 ) and dopamine 250 mcg/min combined with orciprenaline 4 mcg/min ( d 250 + or 4 ) . | NA | {
"id": "C0007412",
"name": "catecholamine",
"pos": [
45,
58
]
} | {
"id": "C0029193",
"name": "mcg",
"pos": [
343,
346
]
} |
apparently the capacity of gerl to metabolize lp is exceeded and lipid accumulates in the residual bodies . | NA | {
"id": "C0023820",
"name": "lp",
"pos": [
46,
48
]
} | {
"id": "C0023779",
"name": "lipid",
"pos": [
65,
70
]
} |
complex formation is decreased at high ratios of heparin to tetrazolium , and divalent cations , even at high concentration , do not precipitate mucopolysaccharides . | NA | {
"id": "C0019134",
"name": "heparin",
"pos": [
49,
56
]
} | {
"id": "C0017973",
"name": "mucopolysaccharides",
"pos": [
145,
164
]
} |
adult cockroaches were found to survive up to 22 weeks when provided with 1 % formalin ( 0.4 % formaldehyde ) in lieu of drinking water . | NA | {
"id": "C0949307",
"name": "formalin",
"pos": [
78,
86
]
} | {
"id": "C0016564",
"name": "formaldehyde",
"pos": [
95,
107
]
} |
the normal flora of cockroaches ( periplaneta americana ) was determined over a period of 24 days prior to substituting water with 1 % formalin for drinking water . | NA | {
"id": "C0043047",
"name": "water",
"pos": [
120,
125
]
} | {
"id": "C0599638",
"name": "drinking",
"pos": [
148,
156
]
} |
when spleen cells from bcg-infected mice were added to either syngeneic or allogeneic normal spleen cells , the mixtures neither proliferated nor developed cytotoxic activity when cultured with alloantigen or with concanavalin a ( con a ) . | NA | {
"id": "C0007634",
"name": "cells",
"pos": [
12,
17
]
} | {
"id": "C3485979",
"name": "allogeneic",
"pos": [
75,
85
]
} |
unbound sds can be removed by electrophoretic passage of eluted solutions through a barrier of triton x-100 in agarose in which the anionic and non-ionic detergents interact to form micelles . | NA | {
"id": "C0003075",
"name": "anionic",
"pos": [
132,
139
]
} | {
"id": "C0022023",
"name": "ionic",
"pos": [
148,
153
]
} |
quantitative and qualitative studies of rh antigen-antibody interactions are for the first time presented at the ultrastructural level , and the application of the uranyl-labelled antibody ( ula ) method for weak antisera ( dilutions 100 to 1000 time higher than the coombs range of sensitivity ) is demonstrated . | NA | {
"id": "C0003241",
"name": "ula",
"pos": [
191,
194
]
} | {
"id": "C0020960",
"name": "antisera",
"pos": [
213,
221
]
} |
the ula method opens a new era for studies of antigens , antibodies and their interactions because it will demonstrate visibly details of the antigen-antibody interaction and is especially suitable for studies of weak antisera . | NA | {
"id": "C0003241",
"name": "antibodies",
"pos": [
57,
67
]
} | {
"id": "C0020960",
"name": "antisera",
"pos": [
218,
226
]
} |
a reverse phase high-pressure liquid chromatography system for rapid separation of various retinoids ( vitamin a and its analogs ) with little or no degradation is described . | NA | {
"id": "C0035339",
"name": "retinoids",
"pos": [
91,
100
]
} | {
"id": "C0042839",
"name": "vitamin a",
"pos": [
103,
112
]
} |
as is generally the case for intact neoplastic tissues , the quantity of 0-alkyl lipids of ehrlich ascites tumor plasma membrane is greater than the amount of alk-1-enyl lipids . | NA | {
"id": "C0025249",
"name": "lipids",
"pos": [
81,
87
]
} | {
"id": "C0023779",
"name": "lipids",
"pos": [
170,
176
]
} |
furthermore , 48 % of the nonturbid supernates contained more than 1 mg/dl ( mean 2.5 mg/dl ) of apob-associated cholesterol when measured by a radial immunodiffusion procedure , indicating slight overestimation of hdl cholesterol . | NA | {
"id": "C0008377",
"name": "cholesterol",
"pos": [
113,
124
]
} | {
"id": "C0023822",
"name": "hdl cholesterol",
"pos": [
215,
230
]
} |
this study investigated the synthesis of membrane antigen ( ma ) as well as virus capsid antigen ( vca ) and early antigen ( ea ) in daudi cells which had been superinfected with the p3hr-1 strain of epstein-barr virus ( ebv ) and then treated with trypsin to remove initially absorbed ma-positive material from the cell surface . | NA | {
"id": "C0003342",
"name": "virus",
"pos": [
76,
81
]
} | {
"id": "C0003320",
"name": "antigen",
"pos": [
115,
122
]
} |
virus could be rescued from these cells by co-cultivation with syngeneic or allogeneic fibroblasts , but the frequency of rescue could not be altered by incubation with cyclic nucleotide analogues , iododeoxyuridine , cortisol , or allogeneic spleen cells . | NA | {
"id": "C0007634",
"name": "cells",
"pos": [
34,
39
]
} | {
"id": "C3485979",
"name": "allogeneic",
"pos": [
232,
242
]
} |
the major influenza a virus structural antigens , matrix protein , nucleoprotein , haemagglutinin and neuraminidase were measured rapidly and accurately using a rocket immunoelectrophoresis technique . | NA | {
"id": "C0033684",
"name": "protein",
"pos": [
57,
64
]
} | {
"id": "C0028612",
"name": "nucleoprotein",
"pos": [
67,
80
]
} |
the diagnosis of krabbe 's leucodystrophy in the affected fetus was confirmed enzymatically by a deficiency of galactosylceramide beta-galactosidase inbrain , liver , kidney , and cultured skin fibroblasts , and histologically by the ultrastructural demonstration of the typical intracellular inclusions in cells of the spinal cord . | NA | {
"id": "C0016030",
"name": "fibroblasts",
"pos": [
194,
205
]
} | {
"id": "C0007634",
"name": "cells",
"pos": [
307,
312
]
} |
the relationship between accumulation of ga-67 in the tumor and the histologic type of tumor was also studied . | NA | {
"id": "C0027651",
"name": "tumor",
"pos": [
54,
59
]
} | {
"id": "C0027652",
"name": "histologic type",
"pos": [
68,
83
]
} |
problems in the interpretation of the in vivo measurement of calcium by the argon-37 method : an investigation of inert-gas elimination in humans . | NA | {
"id": "C0003781",
"name": "argon",
"pos": [
76,
81
]
} | {
"id": "C0017112",
"name": "inert-gas",
"pos": [
114,
123
]
} |
at a chemical dosage of 0.5 mg per kilogram , the content of the heart never exceeded 0.60 % of the administered dose for doxorubicin and 0.55 % for daunorubicin . | NA | {
"id": "C0013089",
"name": "doxorubicin",
"pos": [
122,
133
]
} | {
"id": "C0011015",
"name": "daunorubicin",
"pos": [
149,
161
]
} |
the growth rate increased progressively with each increase in the level of dietary protein up to 25 % protein and then declined . | NA | {
"id": "C0012177",
"name": "dietary protein",
"pos": [
75,
90
]
} | {
"id": "C0033684",
"name": "protein",
"pos": [
102,
109
]
} |
multiple regression analysis of the type : y = beta0 + beta1x1 + beta2x2 + b3x3 + b4x4 where y = rate of weight gain x1 = dietary protein level , x2 = protein efficiency ratio , x3 = appetite factor , and x4 = energy/protein ratio , showed that the maximum rate of weight gain of 58.8 g/week occurred when the diet contained 23 % protein . | NA | {
"id": "C0012177",
"name": "dietary protein",
"pos": [
122,
137
]
} | {
"id": "C0033684",
"name": "protein",
"pos": [
330,
337
]
} |
the relationship between physiologic and anatomic abnormalities seen at autopsy in those who die to the disease suggests that they are due to the same pathologic process . | NA | {
"id": "C0011065",
"name": "die",
"pos": [
93,
96
]
} | {
"id": "C0030660",
"name": "pathologic process",
"pos": [
151,
169
]
} |
the relationship between physiologic and anatomic abnormalities seen at autopsy in those who die to the disease suggests that they are due to the same pathologic process . | NA | {
"id": "C0012634",
"name": "disease",
"pos": [
104,
111
]
} | {
"id": "C0030660",
"name": "pathologic process",
"pos": [
151,
169
]
} |
the structures of silver sulfonamides were found to depend highly on the substituent at the amide nitrogen of the sulfonamide . | NA | {
"id": "C0038760",
"name": "sulfonamides",
"pos": [
25,
37
]
} | {
"id": "C0002482",
"name": "amide",
"pos": [
120,
125
]
} |
the adsorption affinity followed the sequence : ethindrone greater than mestranol greater than norethindrone greater than ethinyl estradiol . | NA | {
"id": "C0025506",
"name": "mestranol",
"pos": [
72,
81
]
} | {
"id": "C0015011",
"name": "ethinyl",
"pos": [
122,
129
]
} |
more accurate estimation of salicylates , particularly aspirin , was achieved by using two different calibration curves . | NA | {
"id": "C0036077",
"name": "salicylates",
"pos": [
28,
39
]
} | {
"id": "C0004057",
"name": "aspirin",
"pos": [
55,
62
]
} |
the inhibition actions of adenosine and adenine nucleotides , such as atp , amp and cyclic amp , on contractions of guinea-pig from ileum induced by transmural stimulation were potentiated by dipyridamole , whereas those of inosine , morphine and tetrodotoxin were not affected . | NA | {
"id": "C0001413",
"name": "adenine nucleotides",
"pos": [
40,
59
]
} | {
"id": "C0001455",
"name": "cyclic amp",
"pos": [
84,
94
]
} |
while the majority of polyploids were triploids resulting from dispermic fertilization , some derived from diploid spermatozoa were also found . | NA | {
"id": "C0032578",
"name": "polyploids",
"pos": [
22,
32
]
} | {
"id": "C0333693",
"name": "triploids",
"pos": [
38,
47
]
} |
seven cases of lupus erythematosus profundus are described ( chronic discoid lupus erythematosus with athrophic panniculitis ) with dissemination of one of them . | NA | {
"id": "C0030327",
"name": "lupus erythematosus profundus",
"pos": [
15,
44
]
} | {
"id": "C0024138",
"name": "chronic discoid",
"pos": [
61,
76
]
} |
the data from x-ray diffraction patterns of two crystal forms ( methanol form i , ethanol form ii ) were reproducible by estimating their relative intensities . | NA | {
"id": "C0001963",
"name": "methanol",
"pos": [
64,
72
]
} | {
"id": "C0001962",
"name": "ethanol",
"pos": [
82,
89
]
} |
experiments showed that sulphadimidine crystals recrystallized from ethanol had better dissolution and absorption characteristics than sulphadimidine crystals recrystallized from methanol . | NA | {
"id": "C0001962",
"name": "ethanol",
"pos": [
68,
75
]
} | {
"id": "C0001963",
"name": "methanol",
"pos": [
179,
187
]
} |
application of that substitution to nerve data suggests that rubidium ions diffuse by a free cation result when the nerve is clamped at its resting potential , but by a vacancy mechanism when the nerve is clamped at zero voltage . | NA | {
"id": "C0022023",
"name": "ions",
"pos": [
70,
74
]
} | {
"id": "C0007447",
"name": "cation",
"pos": [
93,
99
]
} |
thirty-two subjects affected by various types of epilepsy have been studied as follows : 1 ) from the clinical point of view with careful case history or by direct observation of the seizures ; | NA | {
"id": "C0014544",
"name": "types",
"pos": [
40,
45
]
} | {
"id": "C0036572",
"name": "seizures",
"pos": [
183,
191
]
} |
[ atypical case of congenital heart defect : persistent ductus arteriosus with mitral valve insufficiency in a 5-year-old child ] . | NA | {
"id": "C0018798",
"name": "congenital heart defect",
"pos": [
19,
42
]
} | {
"id": "C0013274",
"name": "persistent ductus arteriosus",
"pos": [
45,
73
]
} |
[ comparative studies on the bioequivalency of digoxin ( lanoxin ) and of beta-methyldigoxin ( lanitop ) in patients with cardiac insufficiency ] . | NA | {
"id": "C0012265",
"name": "digoxin",
"pos": [
47,
54
]
} | {
"id": "C0025132",
"name": "beta-methyldigoxin",
"pos": [
74,
92
]
} |
the contribution to this low ratio by the n-acyl group and the amino acid side chain was studied by measuring the rate constants of substrates containing various acyl groups ( benzoyl and benzyloxycarbonyl ) and various side chains ( glycine , alanine , norleucine , citrulline and arginine ) . | NA | {
"id": "C0002520",
"name": "amino acid",
"pos": [
63,
73
]
} | {
"id": "C0017890",
"name": "glycine",
"pos": [
234,
241
]
} |
the contribution to this low ratio by the n-acyl group and the amino acid side chain was studied by measuring the rate constants of substrates containing various acyl groups ( benzoyl and benzyloxycarbonyl ) and various side chains ( glycine , alanine , norleucine , citrulline and arginine ) . | NA | {
"id": "C0002520",
"name": "amino acid",
"pos": [
63,
73
]
} | {
"id": "C0001898",
"name": "alanine",
"pos": [
244,
251
]
} |
the activation of tgo by addition of its coenzyme was assessed using mathematical models uniting the values of tgo recorded with and without pyridoxal phosphate . | NA | {
"id": "C0009235",
"name": "coenzyme",
"pos": [
41,
49
]
} | {
"id": "C0034266",
"name": "pyridoxal phosphate",
"pos": [
141,
160
]
} |
it has been shown that the parabolic model is more suitable than the linear model to explain the relation between transaminase activity determined without pyridoxal phosphate and that measured in the presence of the coenzyme . | NA | {
"id": "C0034266",
"name": "pyridoxal phosphate",
"pos": [
155,
174
]
} | {
"id": "C0009235",
"name": "coenzyme",
"pos": [
216,
224
]
} |
over the past ten years it has become quite apparent that mycotoxins , or toxins produced by fungi , are responsible for a wide variety of human and animal illnesses and , in many cases , deaths . | NA | {
"id": "C0026955",
"name": "mycotoxins",
"pos": [
58,
68
]
} | {
"id": "C0040549",
"name": "toxins",
"pos": [
74,
80
]
} |
degnala disease , which is believed to be a mycotoxicosis , has clinical syndrome similar to chronic ergotism and is characterised by development of oedema , necrosis and gangrene of the legs , tail , ears , etc . | NA | {
"id": "C0027540",
"name": "necrosis",
"pos": [
158,
166
]
} | {
"id": "C0017086",
"name": "gangrene",
"pos": [
171,
179
]
} |
in the present work , characterization , specificity and structure of binary polychelates ( pigment-metal ) n and ternary complexes ( pigment-metal-nucleic acids ) are successively reported : whereas , unspecific complex ii with double-stranded polynucleotides is shown to result from simple adsorption of polychelate onto the double helix , complex i is specific for single-stranded dna ( or polypurine nucleotides ) and results from electrostatic association of separate pigment-metal units with the polyphosphate chain . | NA | {
"id": "C0032550",
"name": "polynucleotides",
"pos": [
245,
260
]
} | {
"id": "C0028630",
"name": "nucleotides",
"pos": [
404,
415
]
} |
patulin , a mycotoxin isolated from cultures of byssochlamis nivea , alters the transcriptional and translational processes . | NA | {
"id": "C0030710",
"name": "patulin",
"pos": [
0,
7
]
} | {
"id": "C0026955",
"name": "mycotoxin",
"pos": [
12,
21
]
} |
the likeness of theoretical and experimental ratio between mycotoxin levels in milk and plasma ultrafiltrates allowed to conclude in favour of the passage through the blood-milk barrier by nonionic passive diffusion of the free toxin . | NA | {
"id": "C0026955",
"name": "mycotoxin",
"pos": [
59,
68
]
} | {
"id": "C0040549",
"name": "toxin",
"pos": [
228,
233
]
} |
during the past few years , the occurrence of kaposi 's sarcoma in the course of cancers , malignant lymphomas and especially during hodgkin 's disease , has been reported . | NA | {
"id": "C0024299",
"name": "malignant lymphomas",
"pos": [
91,
110
]
} | {
"id": "C0019829",
"name": "hodgkin 's disease",
"pos": [
133,
151
]
} |
the study of the patient 's complement revealed a selective defect of the c2 component ( 0 p.100 ) with a drop in total complement ( 6 p. 100 ) . | NA | {
"id": "C0009498",
"name": "complement",
"pos": [
28,
38
]
} | {
"id": "C0009523",
"name": "complement",
"pos": [
120,
130
]
} |
the occurrence and seasonal trends of nematode parasite infections in beef cattle on the tablelands and north coast regions of new south wales are described , based on worm counts from 627 spring-born steers slaughtered at 2-monthly intervals from 6 to 24 months of age . | NA | {
"id": "C0027583",
"name": "nematode",
"pos": [
38,
46
]
} | {
"id": "C0018889",
"name": "worm",
"pos": [
168,
172
]
} |
the urinary excretion of noradrenaline , adrenaline and creatinine has been studied in 22 normal young men during a sauna bath ( 20 minutes ) . | NA | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
25,
38
]
} | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
41,
51
]
} |
phy pretreatment increased cardiac , hepatic and muscle glycogen contents and produced hyperglycaemia in hypothermic winter frogs , and it increased ventricular and muscle glycogen contents during summer and hepatic glycogen during rainy seasons , there being no significant effects on blood sugar . | NA | {
"id": "C0017911",
"name": "glycogen",
"pos": [
56,
64
]
} | {
"id": "C0023902",
"name": "hepatic glycogen",
"pos": [
208,
224
]
} |
in the mouthwash trial chlorhexidine gluconate significantly reduced the incidence , duration and severity of ulcers , whereas in the gel trial chlorhexidine significantly reduced the severity and duration but not the incidence of ulceration . | NA | {
"id": "C0055361",
"name": "chlorhexidine",
"pos": [
23,
36
]
} | {
"id": "C0008196",
"name": "chlorhexidine",
"pos": [
144,
157
]
} |
india showed no abnormal seizure susceptibility or eeg response to photic stimulation and no electro-clinical features of epilepsy after pentylenetetrazol , 40 mg/kg sc.c . | NA | {
"id": "C0036572",
"name": "seizure",
"pos": [
25,
32
]
} | {
"id": "C0014544",
"name": "epilepsy",
"pos": [
122,
130
]
} |
autopsy studies on the remaining five monkeys with increased seizure proneness revealed depressed skull fractures with cortical trauma in four and a neoplasm in one . | NA | {
"id": "C0016658",
"name": "fractures",
"pos": [
104,
113
]
} | {
"id": "C0043251",
"name": "trauma",
"pos": [
128,
134
]
} |
the aa. , having already illustrate the cytohistological characteristics of regenerative gastritis of the peptic ulcer , propose some differential cytological criteria with regard serious chronic atrophic gastritis and differentiated adenocarcinoma . | NA | {
"id": "C0017152",
"name": "gastritis",
"pos": [
89,
98
]
} | {
"id": "C0017154",
"name": "chronic atrophic gastritis",
"pos": [
188,
214
]
} |
a survey was carried out in 3 villages in bali to determine the prevalence of taeniasis in humans and cysticercosis in pigs . | NA | {
"id": "C0039254",
"name": "taeniasis",
"pos": [
78,
87
]
} | {
"id": "C0010678",
"name": "cysticercosis",
"pos": [
102,
115
]
} |
it was found to lower plasma free fatty acids , cholesterol and cholesterol esters , but to increase plasma phospholipids and triglycerides . | NA | {
"id": "C0008377",
"name": "cholesterol",
"pos": [
48,
59
]
} | {
"id": "C0008387",
"name": "cholesterol esters",
"pos": [
64,
82
]
} |
acute renal failure consequent to rhabdomyolysis and myoglobinuria , when treated supportively , carries a good prognosis . | NA | {
"id": "C0035410",
"name": "rhabdomyolysis",
"pos": [
34,
48
]
} | {
"id": "C0027080",
"name": "myoglobinuria",
"pos": [
53,
66
]
} |
three groups of electrocardiopathic manifestations have been individualised : ischemia proving angor ( 288 cases ) , anginose syndromes revealing a myocardic infarct ( 81 cases ) , acute myocardic infarcts ( 62 cases ) . | NA | {
"id": "C0022116",
"name": "ischemia",
"pos": [
78,
86
]
} | {
"id": "C0021308",
"name": "infarct",
"pos": [
197,
204
]
} |
the results presented in this report are compatible with the hypothesis that insulin release by gastrointestinal hormones may be mediated by camp in the b-cell in the case of either glucagon or secretin ; | NA | {
"id": "C0017182",
"name": "gastrointestinal hormones",
"pos": [
96,
121
]
} | {
"id": "C0036534",
"name": "secretin",
"pos": [
194,
202
]
} |
the author concluded that the new antiprotozoal agent is an excellent drug against giardia lamblia infections . | NA | {
"id": "C0003416",
"name": "antiprotozoal agent",
"pos": [
34,
53
]
} | {
"id": "C0003204",
"name": "drug",
"pos": [
70,
74
]
} |
the presence of meniogioma has been reported in association with glioblastoma , oligodendroglioma , astrocytoma , and eosinophilic adenoma . | NA | {
"id": "C0017636",
"name": "glioblastoma",
"pos": [
65,
77
]
} | {
"id": "C0004114",
"name": "astrocytoma",
"pos": [
100,
111
]
} |
acetylcholine , biogenic amines , and certain amino acids were applied by microiontophoresis to parvicellular and magnocellular red nucleus ( rn ) neurons of baboon while recording brachium conjunctivum ( bc ) -evoked and amino acid-evoked unit discharge from these neurons . | NA | {
"id": "C0001041",
"name": "acetylcholine",
"pos": [
0,
13
]
} | {
"id": "C0005496",
"name": "biogenic amines",
"pos": [
16,
31
]
} |
glycine , gamma-aminobutyric acid , and beta-alanine were potent depressants of bc-rn synaptic transmission , amino acid-evoked firing , and spontaneous activity of all rn neurons studied . | NA | {
"id": "C0017890",
"name": "glycine",
"pos": [
0,
7
]
} | {
"id": "C0002520",
"name": "amino",
"pos": [
110,
115
]
} |
although the colour that issued from the reaction of chlorine with 4-nitroaniline is affected by the co-existence of reducing gas , e.g . | NA | {
"id": "C0008209",
"name": "chlorine",
"pos": [
53,
61
]
} | {
"id": "C0017110",
"name": "gas",
"pos": [
126,
129
]
} |
so2 , h2s or organic gas , but this effect may be removed the co-existence of reducing gas , e.g . | NA | {
"id": "C0038777",
"name": "so2",
"pos": [
0,
3
]
} | {
"id": "C0017110",
"name": "gas",
"pos": [
87,
90
]
} |
Subsets and Splits
No saved queries yet
Save your SQL queries to embed, download, and access them later. Queries will appear here once saved.