text
stringlengths 57
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| relation
stringclasses 125
values | h
dict | t
dict |
---|---|---|---|
others are thought to contain carbon , nitrogen , and hydrogen , elements that appear to be lacking on the moon . | NA | {
"id": "C0028158",
"name": "nitrogen",
"pos": [
39,
47
]
} | {
"id": "C0013879",
"name": "elements",
"pos": [
65,
73
]
} |
others are thought to contain carbon , nitrogen , and hydrogen , elements that appear to be lacking on the moon . | NA | {
"id": "C0020275",
"name": "hydrogen",
"pos": [
54,
62
]
} | {
"id": "C0013879",
"name": "elements",
"pos": [
65,
73
]
} |
together , cl and clo form a gas-phase catalytic cycle potentially capable of depleting stratospheric ozone . | NA | {
"id": "C0008209",
"name": "cl",
"pos": [
11,
13
]
} | {
"id": "C0017110",
"name": "gas",
"pos": [
29,
32
]
} |
three bacterial isolates capable of growth on l-threonine medium only when supplemented with branched-chain amino acids , and possessing high l-threonine dehydratase activity , were examined to elucidate the catabolic route for the amino acid . | NA | {
"id": "C0002521",
"name": "branched-chain amino acids",
"pos": [
93,
119
]
} | {
"id": "C0002520",
"name": "amino acid",
"pos": [
232,
242
]
} |
the kinetic properties of the enzyme were thus similar to those of the ; biosynthetic ' isoenzyme from rhodopseudomonas spheroides rather than those of the enteric bacteria . | NA | {
"id": "C0014442",
"name": "enzyme",
"pos": [
30,
36
]
} | {
"id": "C0022173",
"name": "isoenzyme",
"pos": [
88,
97
]
} |
the synthesis of l-threonine dehydratase was constitutive and was not subject to multivalent repression by l-isoleucine or other branched-chain amino acids either singly or in combination . | NA | {
"id": "C0022192",
"name": "l-isoleucine",
"pos": [
107,
119
]
} | {
"id": "C0002521",
"name": "branched-chain amino acids",
"pos": [
129,
155
]
} |
six of 10 microorganisms able to grow on cystine used selenocystine as a sole source of carbon and formed elemental selenium , and one of the isolates , a pseudomonad , was found also to produce selenide . | NA | {
"id": "C0007009",
"name": "carbon",
"pos": [
88,
94
]
} | {
"id": "C0013879",
"name": "elemental",
"pos": [
106,
115
]
} |
amino acid analysis showed that total sulfur amino acids were the most deficient ones , giving a protein score of 42 to the material . | NA | {
"id": "C0002520",
"name": "amino acid",
"pos": [
0,
10
]
} | {
"id": "C0002527",
"name": "sulfur amino acids",
"pos": [
38,
56
]
} |
immobilized enzyme ( s ) kinetics were approximately 50 % slower than those of the free enzyme ( s ) , but there was no significant difference in the effect ph and temperature had on the activity of immobilized and free enzyme ( s ) . | NA | {
"id": "C0014444",
"name": "immobilized",
"pos": [
0,
11
]
} | {
"id": "C0014442",
"name": "enzyme",
"pos": [
220,
226
]
} |
preparation of specifically labeled c- ( lignin ) - and c- ( cellulose ) -lignocelluloses and their decomposition by the microflora of soil . | NA | {
"id": "C0023705",
"name": "lignin",
"pos": [
41,
47
]
} | {
"id": "C0007648",
"name": "cellulose",
"pos": [
79,
88
]
} |
natural lignocelluloses containing c in either their lignin or cellulose ( glucan ) components were prepared by feeding plants l- [ u-c ] phenylalanine or d- [ u-c ] glucose , respectively , through their cut stems . | NA | {
"id": "C0023705",
"name": "lignin",
"pos": [
53,
59
]
} | {
"id": "C0007648",
"name": "cellulose",
"pos": [
63,
72
]
} |
c-substituted p-phenylenediamines will also support low rates of photosystem i-catalyzed cyclic photophosphorylation , but p-phenylenediamine is completely inactive . | NA | {
"id": "C0031468",
"name": "phenylenediamines",
"pos": [
16,
33
]
} | {
"id": "C0048678",
"name": "p-phenylenediamine",
"pos": [
123,
141
]
} |
the mutant also contained less rna and protein per cell and less soluble rna relative to ribosomal rna as compared with the normal genotype . | NA | {
"id": "C0035668",
"name": "rna",
"pos": [
31,
34
]
} | {
"id": "C0035701",
"name": "ribosomal rna",
"pos": [
89,
102
]
} |
in aba-treated mutant plants , rnase activity decreased while rna , protein , the ratio of soluble to ribosomal rna and water content increased . | NA | {
"id": "C0035668",
"name": "rna",
"pos": [
31,
34
]
} | {
"id": "C0035701",
"name": "ribosomal rna",
"pos": [
102,
115
]
} |
the content of rna and protein per cell was similar in both types , but the ratio of soluble to ribosomal rna remained lower in the mutant . | NA | {
"id": "C0035668",
"name": "rna",
"pos": [
15,
18
]
} | {
"id": "C0035701",
"name": "ribosomal rna",
"pos": [
96,
109
]
} |
contrary to aba , kinetin increased rnase activity in the mutant under normal humidity and decreased it under high humidity.a similar incorporation of labeled uridine into rna in normal , mutant , and aba-treated mutant plants under normal humidity suggests that the difference between mutant and normal plants in respect to total , soluble , and ribosomal rna results not from a different rate of rna synthesis but from a different rate of rna degradation , i.e . | NA | {
"id": "C0035668",
"name": "rna",
"pos": [
36,
39
]
} | {
"id": "C0035701",
"name": "ribosomal rna",
"pos": [
347,
360
]
} |
the major effect of these procedures was on the amount of amino acids present , particularly alanine , and the ratio of malate to aspartate . | NA | {
"id": "C0002520",
"name": "amino acids",
"pos": [
58,
69
]
} | {
"id": "C0001898",
"name": "alanine",
"pos": [
93,
100
]
} |
phosphatidyl choline and phosphatidyl ethanolamine are the most abundant lipids in all membranes studied , accounting for 70 % or more of the lipid phosphorus and 50 % or more of the fatty acid . | NA | {
"id": "C0025249",
"name": "lipids",
"pos": [
73,
79
]
} | {
"id": "C0023779",
"name": "lipid",
"pos": [
142,
147
]
} |
glyoxysome membranes and endoplasmic reticulum also contain phosphatidyl inositol ( respectively , 9 and 17 % of the lipid phosphorus ) and free fatty acids ( 13 % of the total fatty acid in each ) . | NA | {
"id": "C0015688",
"name": "free",
"pos": [
140,
144
]
} | {
"id": "C0015684",
"name": "fatty acid",
"pos": [
177,
187
]
} |
about 500 tobacco plants established from protoplasts of a normally tobacco-mosaic virus-susceptible cultivar that had been allowed to absorb dna prepared from a resistant cultivar did not show transfer of the virus-resistant gene.a detailed analysis was performed of the disposition of exogenous dna in plant protoplasts , by employing escherichia coli ( 3 ) h-dna and nicotiana glutinosa protoplasts . | NA | {
"id": "C0012854",
"name": "dna",
"pos": [
142,
145
]
} | {
"id": "C0242964",
"name": "dna",
"pos": [
362,
365
]
} |
the amount of bacterial dna remaining in protoplasts suggests that each protoplast retained 2.3 x 10 ( -15 ) g donor dna , or approximately half of the e. coli genome . | NA | {
"id": "C0012924",
"name": "bacterial dna",
"pos": [
14,
27
]
} | {
"id": "C0012854",
"name": "dna",
"pos": [
117,
120
]
} |
amino acids or amino acid analogues added singly to the induction medium have a similar effect : i.e . when the induction of nitrate reductase is inhibited in the root tips ( lysine , canavanine , azaserine , azetidine-2-carboxylic acid , dl-4-azaleucine , asparagine , and glutamine ) , that inhibition is more severe in mature root sections . | NA | {
"id": "C0002520",
"name": "amino acid",
"pos": [
0,
10
]
} | {
"id": "C0006825",
"name": "canavanine",
"pos": [
184,
194
]
} |
the levels of total sugars , total reducing sugars and free glucose , sucrose and other nonreducing sugars , maltooligosaccharides , and total and nonsucrosyl fructose followed closely the changes in the rate of starch accumulation , in both ir28 and 29 ; | NA | {
"id": "C0038636",
"name": "sucrose",
"pos": [
70,
77
]
} | {
"id": "C0242209",
"name": "sugars",
"pos": [
100,
106
]
} |
phenylalanine ammonia lyase ( pal ) activity was measured in p-fluorophenylalanine ( pfp ) -sensitive and -resistant tobacco ( nicotiana tabacum l. ) and carrot ( daucus carota l. ) cell lines which are known to oversynthesize phenylalanine . | NA | {
"id": "C0030137",
"name": "p-fluorophenylalanine",
"pos": [
61,
82
]
} | {
"id": "C0031453",
"name": "phenylalanine",
"pos": [
227,
240
]
} |
the data support a model in which phosphoenolpyruvate carboxykinase is of physiological significance only during the light period and then only as a decarboxylase . | NA | {
"id": "C0031644",
"name": "phosphoenolpyruvate carboxykinase",
"pos": [
34,
67
]
} | {
"id": "C0007054",
"name": "decarboxylase",
"pos": [
149,
162
]
} |
the enzyme in the cotyledon extracts from seedlings at various ages was resolved into six distinct isozymes by starch gel electrophoresis . | NA | {
"id": "C0014442",
"name": "enzyme",
"pos": [
4,
10
]
} | {
"id": "C0022173",
"name": "isozymes",
"pos": [
99,
107
]
} |
unlike many other chloroplast enzymes , the appearance of the chloroplast transaminase isozymes was under temporal control and was independent of illumination . | NA | {
"id": "C0014442",
"name": "enzymes",
"pos": [
30,
37
]
} | {
"id": "C0022173",
"name": "isozymes",
"pos": [
87,
95
]
} |
data obtained on the level of the reducing sugars , starch , and sucrose in the leaf were related to the speed of translocation . | NA | {
"id": "C0242209",
"name": "sugars",
"pos": [
43,
49
]
} | {
"id": "C0038636",
"name": "sucrose",
"pos": [
65,
72
]
} |
when glutamine was supplied , its nitrogen was rapidly transferred to glutamic acid , asparagine , and other products , and there was some transfer to ammonia . | NA | {
"id": "C0017797",
"name": "glutamine",
"pos": [
5,
14
]
} | {
"id": "C0061472",
"name": "glutamic acid",
"pos": [
70,
83
]
} |
recently detected but unidentified cytokinin activity in crown gall tumor tissue from vinca rosea l. grown on media containing sources of reduced nitrogen has now been attributed to two adenine-type cytokinins . | NA | {
"id": "C0001407",
"name": "adenine",
"pos": [
186,
193
]
} | {
"id": "C0010815",
"name": "cytokinins",
"pos": [
199,
209
]
} |
mass spectroscopic identification of cytokinins : glucosyl zeatin and glucosyl ribosylzeatin from vinca rosea crown gall . | NA | {
"id": "C0010815",
"name": "cytokinins",
"pos": [
37,
47
]
} | {
"id": "C0043456",
"name": "zeatin",
"pos": [
86,
92
]
} |
mass spectrographic and chemical studies of the permethyl and trimethylsilyl ethers of two new cytokinins isolated from vinca rosea crown gall callus cultures by peterson and miller ( plant physiol 59 : 1026-1028 ) indicate that they are 6- ( 4-0-beta-d-glucopyranosyl-3-methyl-trans-but-2-enylamino ) purine ( glucosyl zeatin ) and 9-beta-d-ribofuranosyl-6 ( 4-0-beta-d-glucopyranosyl-3-methyl-trans-but-2-enylamino ) purine ( glucosyl ribosylzeatin ) . | NA | {
"id": "C0010815",
"name": "cytokinins",
"pos": [
95,
105
]
} | {
"id": "C0043456",
"name": "zeatin",
"pos": [
444,
450
]
} |
foliar applied cytokinins delayed senescence , and zeatin at 0.1 mm delayed the onset of the irreversible stage for 6 days . | NA | {
"id": "C0010815",
"name": "cytokinins",
"pos": [
15,
25
]
} | {
"id": "C0043456",
"name": "zeatin",
"pos": [
51,
57
]
} |
abscisic acid enhanced the absorption of ( 14 ) c-sucrose and the accumulation of sugars in buds cultured at high levels of sucrose . | NA | {
"id": "C0038636",
"name": "sucrose",
"pos": [
50,
57
]
} | {
"id": "C0242209",
"name": "sugars",
"pos": [
82,
88
]
} |
increased unsaturation of fatty acids is therefore probably an important part of the mechanism of cold adaptation in winter wheat.basf 13-338 also prevents the increase in per cent dry weight in roots and shoots during hardening and causes a decrease in root lipid phosphorus and total fatty acids . | NA | {
"id": "C0015690",
"name": "unsaturation",
"pos": [
10,
22
]
} | {
"id": "C0015684",
"name": "fatty",
"pos": [
286,
291
]
} |
similarly , when slices were exposed to the choline analogue dimethylaminoethanol within the first 10 hours , the phospholipid composition of the membrane lipids was drastically altered , the wound-induced respiration in a 24-hr period was substantially curtailed , and the development of cyanide insensitivity was sharply inhibited . | NA | {
"id": "C0031676",
"name": "phospholipid",
"pos": [
114,
126
]
} | {
"id": "C0025249",
"name": "membrane lipids",
"pos": [
146,
161
]
} |
in investigations of glycolate and photorespiratory metabolism , separate labeling data should be obtained for glycine and serine as those two amino acids may be produced from different precursors and respond differently to environmental perturbations . | NA | {
"id": "C0017890",
"name": "glycine",
"pos": [
111,
118
]
} | {
"id": "C0002520",
"name": "amino acids",
"pos": [
143,
154
]
} |
it is concluded that d-glucose and other hexoses are transported by carrier-mediated diffusion across the inner envelope membrane . | NA | {
"id": "C0017725",
"name": "glucose",
"pos": [
23,
30
]
} | {
"id": "C0019494",
"name": "hexoses",
"pos": [
41,
48
]
} |
when the seven most abundant amino acids in phloem exudate of pea fruits ( asparagine , serine , glutamine , homoserine , alanine , aspartate , glycine ) were fed singly , their carbon was distributed widely among the aliphatic amino acids , proline and tryptophan ; | NA | {
"id": "C0019892",
"name": "homoserine",
"pos": [
109,
119
]
} | {
"id": "C0002520",
"name": "amino",
"pos": [
228,
233
]
} |
when the seven most abundant amino acids in phloem exudate of pea fruits ( asparagine , serine , glutamine , homoserine , alanine , aspartate , glycine ) were fed singly , their carbon was distributed widely among the aliphatic amino acids , proline and tryptophan ; | NA | {
"id": "C0001898",
"name": "alanine",
"pos": [
122,
129
]
} | {
"id": "C0002520",
"name": "amino",
"pos": [
228,
233
]
} |
when the seven most abundant amino acids in phloem exudate of pea fruits ( asparagine , serine , glutamine , homoserine , alanine , aspartate , glycine ) were fed singly , their carbon was distributed widely among the aliphatic amino acids , proline and tryptophan ; | NA | {
"id": "C0017890",
"name": "glycine",
"pos": [
144,
151
]
} | {
"id": "C0002520",
"name": "amino",
"pos": [
228,
233
]
} |
influence of the level of nitrate nutrition on ion uptake and assimilation , organic acid accumulation , and cation-anion balance in whole tomato plants . | NA | {
"id": "C0028125",
"name": "nitrate",
"pos": [
26,
33
]
} | {
"id": "C0003075",
"name": "anion",
"pos": [
116,
121
]
} |
influence of the level of nitrate nutrition on ion uptake and assimilation , organic acid accumulation , and cation-anion balance in whole tomato plants . | NA | {
"id": "C0022023",
"name": "ion",
"pos": [
40,
43
]
} | {
"id": "C0007447",
"name": "cation",
"pos": [
109,
115
]
} |
influence of the level of nitrate nutrition on ion uptake and assimilation , organic acid accumulation , and cation-anion balance in whole tomato plants . | NA | {
"id": "C0022023",
"name": "ion",
"pos": [
40,
43
]
} | {
"id": "C0003075",
"name": "anion",
"pos": [
116,
121
]
} |
it is suggested that increasing the level of no ( 3 ) nutrition to tomato plants stimulates cation uptake and translocation as counter-ions are required to accompany no ( 3 ) ( - ) ions to the upper plant parts , the major site of no ( 3 ) reduction . | NA | {
"id": "C0007447",
"name": "cation",
"pos": [
92,
98
]
} | {
"id": "C0022023",
"name": "ions",
"pos": [
181,
185
]
} |
on no ( 3 ) reduction , the resulting stoichiometric accumulation of organic anions is balanced by the cations originally accompanying no ( 3 ) ( - ) ions . | NA | {
"id": "C0007447",
"name": "cations",
"pos": [
103,
110
]
} | {
"id": "C0022023",
"name": "ions",
"pos": [
150,
154
]
} |
the water efflux rate required for ice formation to occur extracellularly was calculated from the rate of ice formation and the average cell diameter . | NA | {
"id": "C0043047",
"name": "water",
"pos": [
4,
9
]
} | {
"id": "C0020746",
"name": "ice",
"pos": [
106,
109
]
} |
the water potential difference driving the efflux of water to sites of extracellular ice was calculated from the sample temperature , osmotic water potential , and fraction of water frozen at a given freezing temperature . | NA | {
"id": "C0020746",
"name": "ice",
"pos": [
85,
88
]
} | {
"id": "C0043047",
"name": "water",
"pos": [
176,
181
]
} |
from the water efflux rate and water potential difference , the resistance of the barrier controlling movement of intracellular water to sites of extracellular ice was calculated . | NA | {
"id": "C0043047",
"name": "water",
"pos": [
9,
14
]
} | {
"id": "C0020746",
"name": "ice",
"pos": [
160,
163
]
} |
thus , membrane resistance can have little influence on the rate of water efflux and ice formation when bark is cooled at a rate of 31 c per minute . | NA | {
"id": "C0043047",
"name": "water",
"pos": [
68,
73
]
} | {
"id": "C0020746",
"name": "ice",
"pos": [
85,
88
]
} |
there is evidence that the edta effects result from chelation of calcium ions rather than chelation of other cations . | NA | {
"id": "C0022023",
"name": "ions",
"pos": [
73,
77
]
} | {
"id": "C0007447",
"name": "cations",
"pos": [
109,
116
]
} |
acidification of the suspending medium of corn mitochondria ( zea mays l. , wf9 x mo17 ) from ph 7.5 to ph 6.8 to 6.4 initiates osmotic swelling with the transportable anions citrate , sulfate , and phosphate . | NA | {
"id": "C0003075",
"name": "anions",
"pos": [
168,
174
]
} | {
"id": "C0038720",
"name": "sulfate",
"pos": [
185,
192
]
} |
acidification of the suspending medium of corn mitochondria ( zea mays l. , wf9 x mo17 ) from ph 7.5 to ph 6.8 to 6.4 initiates osmotic swelling with the transportable anions citrate , sulfate , and phosphate . | NA | {
"id": "C0003075",
"name": "anions",
"pos": [
168,
174
]
} | {
"id": "C0031603",
"name": "phosphate",
"pos": [
199,
208
]
} |
stimulated emission and lasing have been demonstrated for chlorophyll a , chlorophyll b , and bacteriochlorophyll a as well as for the mg-free chlorophyll derivatives pheophytin a and methyl pheophorbide a . | NA | {
"id": "C0008260",
"name": "chlorophyll",
"pos": [
58,
69
]
} | {
"id": "C0031512",
"name": "pheophytin",
"pos": [
167,
177
]
} |
a new crystal form ( iii ) of tobacco leaf ribulosebisphosphate carboxylase [ 3-phospho-d-glycerate carboxy-lyase ( dimerizing ) , ec 4.1.1.39 ] has been grown by dialysis procedures , and is suitable for structural studies at near atomic resolution . | NA | {
"id": "C0035565",
"name": "ribulosebisphosphate carboxylase",
"pos": [
43,
75
]
} | {
"id": "C0007054",
"name": "carboxy-lyase",
"pos": [
100,
113
]
} |
arf and ptf are not involved in derepression of dopa decarboxylase ( aromatic l-amino-acid decarboxylase , aromatic l-amino-acid carboxy-lyase , ec 4.1.1.28 ) synthesis initiated by ecdysone . | NA | {
"id": "C0003806",
"name": "dopa decarboxylase",
"pos": [
48,
66
]
} | {
"id": "C1412028",
"name": "aromatic l-amino-acid carboxy-lyase",
"pos": [
107,
142
]
} |
the syndrome can not be considered in isolation from the patient 's personality , however , since this will affect his coping with the disorder . | NA | {
"id": "C0039082",
"name": "syndrome",
"pos": [
4,
12
]
} | {
"id": "C0012634",
"name": "disorder",
"pos": [
135,
143
]
} |
allopurinol 300 mg once daily was compared with allopurinol , 100 mg tid in 17 patients with gouty arthritis and/or gouty nephrolithiasis . | NA | {
"id": "C0003868",
"name": "gouty arthritis",
"pos": [
93,
108
]
} | {
"id": "C0018099",
"name": "gouty",
"pos": [
116,
121
]
} |
the quantitative effect of organo-mineral complex ( containing the active degradative ingredient ) additions to sand and silt fractions on the rate of subsequent malathion decay is also described . | NA | {
"id": "C0026162",
"name": "mineral",
"pos": [
34,
41
]
} | {
"id": "C0037098",
"name": "sand",
"pos": [
112,
116
]
} |
special emphasis is placed on their content of glycoproteins , fibrous proteins , proteins susceptible to rapid phosphorylation and dephosphorylation , and receptors for various putative neurotransmitters . | NA | {
"id": "C0036425",
"name": "fibrous proteins",
"pos": [
63,
79
]
} | {
"id": "C0033684",
"name": "proteins",
"pos": [
82,
90
]
} |
of the ( 14 ) c released , 2-3 % was as 5'-adenine nucleotides and about 2 % as cyclic adenosine 3 ? 5-monophosphate ( camp ) . | NA | {
"id": "C0001413",
"name": "adenine nucleotides",
"pos": [
43,
62
]
} | {
"id": "C0001455",
"name": "adenosine",
"pos": [
87,
96
]
} |
a fraction of this presumptive messenger rna moves distally to the optic tectum together with nonpolyadenylic acid-containing rna . | NA | {
"id": "C0035696",
"name": "messenger rna",
"pos": [
31,
44
]
} | {
"id": "C0035668",
"name": "rna",
"pos": [
126,
129
]
} |
the effect of intramuscular administration of hydrocortisone ( 10 mg/day per animal ) for 5 days has been studied on the content of the amino acids belonging to the glutamate family , in the different regions of the mouse brain , along with the activities of glutamine synthetase , glutamate dehydrogenase , and aspartate , alanine , tyrosine , and ornithine aminotransferases . | NA | {
"id": "C0002520",
"name": "amino acids",
"pos": [
136,
147
]
} | {
"id": "C0001898",
"name": "alanine",
"pos": [
324,
331
]
} |
acute effects of intraperitoneal administration of ammonium chloride ( 200 mg/kg ) on na ( + ) , k ( + ) -atpase and amino acid content of the glutamate family ( glutamate , aspartate , alanine , glutamine , and gaba ) , as well as the enzymes involved in the metabolism of these amino acids , have been studied in the different regions of brain and liver in mice . | NA | {
"id": "C0002520",
"name": "amino acid",
"pos": [
117,
127
]
} | {
"id": "C0001898",
"name": "alanine",
"pos": [
186,
193
]
} |
a study was made of ( a ) the distribution of the coenzyme pyridoxal-5'-phosphate ( plp ) in four discrete regions of developing and mature rat brains and ( b ) the effect of dietary pyridoxine deficiency on the distribution . | NA | {
"id": "C0009235",
"name": "coenzyme",
"pos": [
50,
58
]
} | {
"id": "C0034266",
"name": "pyridoxal-5",
"pos": [
59,
70
]
} |
the ( 14 ) c activity in lignified sieve elements was not above background levels , whereas it was significnatly higher in normal sieve elements and companion cells . | NA | {
"id": "C0007009",
"name": "c",
"pos": [
11,
12
]
} | {
"id": "C0013879",
"name": "elements",
"pos": [
136,
144
]
} |
antisera were raised in rabbits against both the matrix proteins and sodium dodecyl sulphate ( sds ) -solubilized membrane proteins . | NA | {
"id": "C0033684",
"name": "proteins",
"pos": [
56,
64
]
} | {
"id": "C0025252",
"name": "membrane",
"pos": [
114,
122
]
} |
in diatoms , the siliceous cell walls are enveloped by an organic component which includes 4-hydroxyproline and 3,4-dihydroxy-l-proline . | NA | {
"id": "C0020388",
"name": "4-hydroxyproline",
"pos": [
91,
107
]
} | {
"id": "C0033382",
"name": "proline",
"pos": [
128,
135
]
} |
its conversion to peptidyl hydroxyproline was shown in cell-free extracts and in kinetic studies using [ ( 14 ) c ] proline . | NA | {
"id": "C0020388",
"name": "hydroxyproline",
"pos": [
27,
41
]
} | {
"id": "C0033382",
"name": "proline",
"pos": [
116,
123
]
} |
two lines of evidence indicate that dihydroxyproline does not arise from the further hydroxylation of peptidyl hydroxyproline : first , there was a lag of several minutes between the incorporation of [ ( 14 ) c ] proline into protein and the appearance therein of [ ( 14 ) c ] hydroxyproline but no such lag for the appearance of dihydroxyproline . | NA | {
"id": "C0033382",
"name": "proline",
"pos": [
45,
52
]
} | {
"id": "C0020388",
"name": "hydroxyproline",
"pos": [
332,
346
]
} |
`` `` killer '' '' , a substance extracted from stem tissue of etiolated pea seedlings ( pisum sativum l. v. alaska ) , interacts specifically with the far-red-absorbing form of phytochrome ( pfr ) in vitro in a temperature-independent , rapid , stoichiometric fashion to cause a loss of phytochrome photoreversibility . | NA | {
"id": "C0031857",
"name": "f phytochro",
"pos": [
176,
187
]
} | {
"id": "C0250581",
"name": "e",
"pos": [
308,
309
]
} |
these messenger rnas were absent , or present in much lower amounts , in polyribosomal messenger rna from leaves of dark-grown plants , although they were present in total cell poly ( a ) -containing rna . | NA | {
"id": "C0035696",
"name": "messenger rna",
"pos": [
6,
19
]
} | {
"id": "C0035668",
"name": "rna",
"pos": [
200,
203
]
} |
the enzyme glucosylated the following flavonols predominantly at the 3-position : quercetin ( km 126 mum ) , kaempferol ( km 172 mum ) , isorhamnetin ( km 200 mum ) and fisetin ( km 270 mum ) . | NA | {
"id": "C0060444",
"name": "flavonols",
"pos": [
38,
47
]
} | {
"id": "C0034392",
"name": "quercetin",
"pos": [
82,
91
]
} |
on the basis of the zein content in acidic and basic amino acids , and of the respective pi 's exhibited in ief ( mostly in the ph range 7-8 ) it has been calculated that at least 90 % of the glutamic and aspartic acids ( ? 52 residues out of a total of ? 190 ) are present as asparagine and glutamine . | NA | {
"id": "C0301714",
"name": "basic amino acids",
"pos": [
47,
64
]
} | {
"id": "C0003995",
"name": "asparagine",
"pos": [
277,
287
]
} |
on the basis of the zein content in acidic and basic amino acids , and of the respective pi 's exhibited in ief ( mostly in the ph range 7-8 ) it has been calculated that at least 90 % of the glutamic and aspartic acids ( ? 52 residues out of a total of ? 190 ) are present as asparagine and glutamine . | NA | {
"id": "C0301714",
"name": "basic amino acids",
"pos": [
47,
64
]
} | {
"id": "C0017797",
"name": "glutamine",
"pos": [
292,
301
]
} |
aggregation at high enzyme concentrations was observed with the glyoxysomal but not with the mitochondrial isoenzyme . | NA | {
"id": "C0014442",
"name": "enzyme",
"pos": [
20,
26
]
} | {
"id": "C0022173",
"name": "isoenzyme",
"pos": [
107,
116
]
} |
of the five major polypeptide components , two had kinetics of breakdown similar to those of stroma proteins and were lost from ny and y at about the same rate , whereas the remaining three ( one of which was tentatively identified as the apoprotein of the light-harvesting chlorophyll-protein complex ) were more stable in ny than in y . | NA | {
"id": "C0033684",
"name": "proteins",
"pos": [
100,
108
]
} | {
"id": "C0003601",
"name": "apoprotein",
"pos": [
239,
249
]
} |
the amino acid composition of roots and leaves differed : glutamine+glutamate were relatively more important in leaves than in roots whereas alanine was a more important constituent of roots than of leaves . | NA | {
"id": "C0002520",
"name": "amino acid",
"pos": [
4,
14
]
} | {
"id": "C0001898",
"name": "alanine",
"pos": [
141,
148
]
} |
the enzyme is inhibited by pyridoxal phosphate in a manner which suggests that pyridoxal phosphate forms a non-covalent complex with the enzymes which is in equilibrium with the schiff base covalently modified enzyme . | NA | {
"id": "C0026741",
"name": "complex",
"pos": [
120,
127
]
} | {
"id": "C0014442",
"name": "enzyme",
"pos": [
210,
216
]
} |
anion exchange experiments with ( 35 ) s-preloaded chloroplasts indicate that sulfite and sulfate are exchanged for inorganic phosphate , phosphoglyceric acid , and dihydroxyacetone phosphate with rates up to 14 nmol mg chlorophyll ( -1 ) min ( -1 ) . | NA | {
"id": "C0003075",
"name": "anion",
"pos": [
0,
5
]
} | {
"id": "C0038750",
"name": "sulfite",
"pos": [
78,
85
]
} |
anion exchange experiments with ( 35 ) s-preloaded chloroplasts indicate that sulfite and sulfate are exchanged for inorganic phosphate , phosphoglyceric acid , and dihydroxyacetone phosphate with rates up to 14 nmol mg chlorophyll ( -1 ) min ( -1 ) . | NA | {
"id": "C0003075",
"name": "anion",
"pos": [
0,
5
]
} | {
"id": "C0038720",
"name": "sulfate",
"pos": [
90,
97
]
} |
anion exchange experiments with ( 35 ) s-preloaded chloroplasts indicate that sulfite and sulfate are exchanged for inorganic phosphate , phosphoglyceric acid , and dihydroxyacetone phosphate with rates up to 14 nmol mg chlorophyll ( -1 ) min ( -1 ) . | NA | {
"id": "C0003075",
"name": "anion",
"pos": [
0,
5
]
} | {
"id": "C0031603",
"name": "inorganic",
"pos": [
116,
125
]
} |
this , presumably , resulted from rapid metabolism of the compound and excretion of mercuric ion in the kidney and colon . | NA | {
"id": "C0025519",
"name": "metabolism",
"pos": [
40,
50
]
} | {
"id": "C0221102",
"name": "excretion",
"pos": [
71,
80
]
} |
[ hypothalamo-hypophyseal complex and regulation of water and electrolyte metabolism in the albino rat submitted to the influence of negative air ions ] . | NA | {
"id": "C0013832",
"name": "electrolyte",
"pos": [
62,
73
]
} | {
"id": "C0022023",
"name": "ions",
"pos": [
146,
150
]
} |
the following endocrine function parameters were studied serially in a group of 10 patients with recent myocardial infarction : blood and urinary levels of epinephrine and norepinephrine , urinary excretion of vanillyl-mandelic acid ; | NA | {
"id": "C0014563",
"name": "epinephrine",
"pos": [
156,
167
]
} | {
"id": "C0028351",
"name": "norepinephrine",
"pos": [
172,
186
]
} |
glucose and insulin secretory response patterns during glucose tolerance tests were determined in 28 maturity-onset diabetics , and the sequential effects of diet and a sulphonylurea , tolazamide , were assessed . | NA | {
"id": "C0038766",
"name": "sulphonylurea",
"pos": [
169,
182
]
} | {
"id": "C0040372",
"name": "tolazamide",
"pos": [
185,
195
]
} |
certainly a number of patients had steatorrhoea , and in these it is most likely that malabsorption was the major factor . | NA | {
"id": "C0038238",
"name": "steatorrhoea",
"pos": [
35,
47
]
} | {
"id": "C0024523",
"name": "malabsorption",
"pos": [
86,
99
]
} |
a reproducible , reliable method for determination of progesterone ( p ) and 20 alpha-dihydroprogesterone ( 20 alpha p ) in small volumes of plasma or serum , suitable for a range of concentrations from follicular phase to late pregnancy values . | NA | {
"id": "C0033308",
"name": "progesterone",
"pos": [
54,
66
]
} | {
"id": "C0012311",
"name": "20",
"pos": [
108,
110
]
} |
from the time required for abrogation to occur after transfer of the allogeneic cells , it is suggested that tolerance of sheep erythrocytes in rats represents the repression of a specific reactivity in cells rather than the elimination or irreversible inactivation of reactive cells . | NA | {
"id": "C3485979",
"name": "allogeneic cells",
"pos": [
69,
85
]
} | {
"id": "C0007634",
"name": "cells",
"pos": [
278,
283
]
} |
such conformational changes , if they occur , must be restricted since hapten has little effect on the reactions of f ( ab ' ) ( 2 ) fragments of anti-benzoate antibodies with antisera directed to rabbit fragment fab and no detectable effect on reactions with antibodies directed to allotypic determinants . | NA | {
"id": "C0020960",
"name": "antisera",
"pos": [
176,
184
]
} | {
"id": "C0003241",
"name": "antibodies",
"pos": [
260,
270
]
} |
the theory , in addition , is in reasonable accord with nonequimolar ion flow , and provides an explanation for such effects as the following : the intercept of the voltage-current characteristic , the ion membrane concentrations inferred from electrodiffusion theories , and the effects of polyvalent cations | NA | {
"id": "C0022023",
"name": "ion",
"pos": [
21,
24
]
} | {
"id": "C0007447",
"name": "cations",
"pos": [
302,
309
]
} |
hypocalcaemia was related to high dosage of anticonvulsant drugs , to multiple drug therapy , and to the use of individual anticonvulsant drugs in the following order , with decreasing order of importance : pheneturide , primidone , phenytoin , phenobarbitone . | NA | {
"id": "C0033148",
"name": "primidone",
"pos": [
221,
230
]
} | {
"id": "C0031412",
"name": "phenobarbitone",
"pos": [
245,
259
]
} |
glucose oxidation was inhibited by mannoheptulose and glucosamine but not by phlorrhizin , 2-deoxyglucose or n-acetylglucosamine . | NA | {
"id": "C0017718",
"name": "glucosamine",
"pos": [
54,
65
]
} | {
"id": "C0001056",
"name": "n-acetylglucosamine",
"pos": [
109,
128
]
} |
double mutants isolated by this procedure are unable to grow on n-acetylglucosamine and grow poorly on glucosamine . | NA | {
"id": "C0001056",
"name": "acetylglucosamine",
"pos": [
66,
83
]
} | {
"id": "C0017718",
"name": "glucosamine",
"pos": [
103,
114
]
} |
wall samples extracted with trichloroacetic acid under carefully controlled conditions were found to contain various amounts of phosphorus , this being present as a glycerol phosphate polymer containing hexose ( glucose and in some cases galactose ) , i.e . a teichoic aid . | NA | {
"id": "C0019494",
"name": "hexose",
"pos": [
203,
209
]
} | {
"id": "C0016945",
"name": "galactose",
"pos": [
238,
247
]
} |
the order of potency of sympathomimetic amines in causing contraction of strips of human saphenous vein was ( - ) -adrenaline > ( - ) -noradrenaline > ( - ) -phenylephrine > ( +/- ) -isoprenaline.2 . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
115,
125
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
135,
148
]
} |
following either a single injection of radiolabelled pge ( 1 ) or pgf ( 1alpha ) into the hepatic artery or portal vein , or recirculation of prostaglandins through the liver for 2.5 h , the distribution of radioactivity within extracts of bile , blood and liver was determined . | NA | {
"id": "C0033559",
"name": "pge",
"pos": [
53,
56
]
} | {
"id": "C0033554",
"name": "prostaglandins",
"pos": [
142,
156
]
} |
studies with 5,6- ( 3 ) h pge ( 1 ) , and comparison with the results obtained using 1- ( 14 ) c pge ( 1 ) , revealed a 30-fold increase in the percentage of radioactivity excreted into the bile , suggesting that biliary excretion may be a major route for elimination of compounds smaller than c20 prostaglandin . | NA | {
"id": "C0033559",
"name": "pge",
"pos": [
26,
29
]
} | {
"id": "C0033554",
"name": "prostaglandin",
"pos": [
298,
311
]
} |
the effects of adrenaline , noradrenaline , isoprenaline and terbutaline ( pinn ) , 1- ( 3,5-dihydroxyphenyl ) -2 ( t-butylamino ) -ethanol , on the sphincter of oddi were studied in anaesthetized cats . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
15,
25
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
28,
41
]
} |
exercise-induced asthma ( defined as a fall in pef of at least 25 % of the pre-exercise value ) was studied in adult patients with uncomplicated asthma . | NA | {
"id": "C0004099",
"name": "exercise-induced asthma",
"pos": [
0,
23
]
} | {
"id": "C0004096",
"name": "asthma",
"pos": [
145,
151
]
} |
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