text
stringlengths 57
1.72k
| relation
stringclasses 125
values | h
dict | t
dict |
|---|---|---|---|
treatment of edema with amiloride alone and in combination with hydrochlorothiazide , chlorothiazide and ethacrynic acid . | NA | {
"id": "C0020261",
"name": "hydrochlorothiazide",
"pos": [
64,
83
]
} | {
"id": "C0008273",
"name": "chlorothiazide",
"pos": [
86,
100
]
} |
[ treatment of fractures of the long tubular bones , ununited fractures and pseudoarthrosis with an extracortical compressing plate ] . | NA | {
"id": "C0016665",
"name": "ununited fractures",
"pos": [
53,
71
]
} | {
"id": "C0033785",
"name": "pseudoarthrosis",
"pos": [
76,
91
]
} |
[ use of prostaglandin ( pge 1 ) in the analysis of the mechanism of the activity of catecholamines ] . | NA | {
"id": "C0033554",
"name": "prostaglandin",
"pos": [
9,
22
]
} | {
"id": "C0033559",
"name": "pge",
"pos": [
25,
28
]
} |
the apo-lipoproteins of human plasma high density lipoprotein : a study of their lipid binding capacity and interaction with lipid monolayers . | NA | {
"id": "C0023820",
"name": "lipoproteins",
"pos": [
8,
20
]
} | {
"id": "C0023779",
"name": "lipid",
"pos": [
125,
130
]
} |
free fatty acid utilization by mammalian cell suspension comparison between individual fatty acids and fatty acid mixtures . | NA | {
"id": "C0015688",
"name": "free fatty acid",
"pos": [
0,
15
]
} | {
"id": "C0015684",
"name": "fatty acid",
"pos": [
103,
113
]
} |
when the washed ribosomes were incubated with toxin before addition of messenger ribonucleic acid ( rna ) , peptide syntheses of ( 14 ) c-phenylalanine directed by polyuridylic acid or phage r17 rna were strongly inhibited by a small amount of toxin . | NA | {
"id": "C0035696",
"name": "messenger ribonucleic acid",
"pos": [
71,
97
]
} | {
"id": "C0035668",
"name": "rna",
"pos": [
195,
198
]
} |
the binding of ( 3 ) h-formylmethionyl-transfer rna to e. coli ribosomes directed by either r17 rna or trinucleotide aug was also decreased by toxin . | NA | {
"id": "C0035711",
"name": "transfer rna",
"pos": [
39,
51
]
} | {
"id": "C0035668",
"name": "rna",
"pos": [
96,
99
]
} |
preparations of p582 catalyzed the reduced methyl viologen ( mvh ) -linked reduction of sulfite , hydroxylamine , and nitrite but not of sulfate , thiosulfate , or nitrate . | NA | {
"id": "C0038720",
"name": "sulfate",
"pos": [
137,
144
]
} | {
"id": "C0039950",
"name": "thiosulfate",
"pos": [
147,
158
]
} |
in this study , evidence has been obtained which suggests that coenzyme repression by biotin is an indirect effect ; | NA | {
"id": "C0009235",
"name": "coenzyme",
"pos": [
63,
71
]
} | {
"id": "C0005575",
"name": "biotin",
"pos": [
86,
92
]
} |
induction of penicillinase ( beta-lactamase ) in bacillus licheniformis 749 by 2- ( 2'-carboxyphenyl ) -benzoyl-6-aminopenicillanic acid ( cbap ) was examined , since this compound was reported to be a gratuitous inducer of penicillinase in staphylococcus aureus . | NA | {
"id": "C0597979",
"name": "beta-lactamase",
"pos": [
29,
43
]
} | {
"id": "C0030841",
"name": "penicillinase",
"pos": [
224,
237
]
} |
electrophoretic studies on habu snake venom ( trimeresurus flavoviridis ) , with special reference to the changes in consecutive venom collection . | NA | {
"id": "C0037380",
"name": "snake venom",
"pos": [
32,
43
]
} | {
"id": "C0042479",
"name": "venom",
"pos": [
129,
134
]
} |
optical rotatory dispersion and circular dichroism of glycosaminoglycans and heparan sulfate fractions from the urine of patients with mucopolysaccharidosis ( hurler syndrome ) . | NA | {
"id": "C0017973",
"name": "glycosaminoglycans",
"pos": [
54,
72
]
} | {
"id": "C0019143",
"name": "heparan sulfate",
"pos": [
77,
92
]
} |
[ von hippel-lindau disease . treatment of retinal angiomatosis with photocoagulation and of cerebellar localization with neurosurgical exeresis ] . | NA | {
"id": "C0019562",
"name": "von hippel-lindau disease",
"pos": [
2,
27
]
} | {
"id": "C0002992",
"name": "angiomatosis",
"pos": [
51,
63
]
} |
phosphorylation coupled to oxidation of thiol groups ( gsh ) by cytochrome c with disulfide ( gssg ) as an essential catalyst . | NA | {
"id": "C0017817",
"name": "gsh",
"pos": [
55,
58
]
} | {
"id": "C0061516",
"name": "gssg",
"pos": [
94,
98
]
} |
phosphorylation coupled to oxidation of thiol groups ( gsh ) by cytochrome c with disulfide ( gssg ) as an essential catalyst . | NA | {
"id": "C0017817",
"name": "gsh",
"pos": [
55,
58
]
} | {
"id": "C0061516",
"name": "gssg",
"pos": [
94,
98
]
} |
phosphorylation coupled to oxidation of thiol groups ( gsh ) by cytochrome c with disulfide ( gssg ) as an essential catalyst . | NA | {
"id": "C0017817",
"name": "gsh",
"pos": [
55,
58
]
} | {
"id": "C0061516",
"name": "gssg",
"pos": [
94,
98
]
} |
phosphorylation coupled to oxidation of thiol groups ( gsh ) by cytochrome c with disulfide ( gssg ) as an essential catalyst . | NA | {
"id": "C0017817",
"name": "gsh",
"pos": [
55,
58
]
} | {
"id": "C0061516",
"name": "gssg",
"pos": [
94,
98
]
} |
[ blood glucose and serum insulin after oral loading with glucose and starch syrup in varying doses ] . | NA | {
"id": "C0005802",
"name": "blood glucose",
"pos": [
2,
15
]
} | {
"id": "C0017725",
"name": "glucose",
"pos": [
58,
65
]
} |
of especial interest is the observation that 2-aminopurine may be viewed as an analogue of either guanine or adenine , depending on which enzymatic step is being considered . | NA | {
"id": "C0000263",
"name": "2-aminopurine",
"pos": [
45,
58
]
} | {
"id": "C0001407",
"name": "adenine",
"pos": [
109,
116
]
} |
although purified rps was not immunogenic in rabbits , it was presumed to be a major antigen of the cell because it could specifically absorb approximately one-third of the antibody nitrogen in antisera prepared against whole cells of r. dentocariosa . | NA | {
"id": "C0003241",
"name": "antibody",
"pos": [
173,
181
]
} | {
"id": "C0020960",
"name": "antisera",
"pos": [
194,
202
]
} |
the heating of formaldehyde and ammonia yields a product that , on hydrolysis , is converted into seven amino acids : aspartic acid , glutamic acid , serine , proline , valine , glycine , and alanine . | NA | {
"id": "C0002520",
"name": "amino acids",
"pos": [
104,
115
]
} | {
"id": "C0017890",
"name": "glycine",
"pos": [
178,
185
]
} |
the heating of formaldehyde and ammonia yields a product that , on hydrolysis , is converted into seven amino acids : aspartic acid , glutamic acid , serine , proline , valine , glycine , and alanine . | NA | {
"id": "C0002520",
"name": "amino acids",
"pos": [
104,
115
]
} | {
"id": "C0001898",
"name": "alanine",
"pos": [
192,
199
]
} |
this conformation is not present in gamma globulin , bence-jones protein , albumin , fibrinogen , or other proteins tested so far . | NA | {
"id": "C0001924",
"name": "albumin",
"pos": [
75,
82
]
} | {
"id": "C0033684",
"name": "proteins",
"pos": [
107,
115
]
} |
it is possible that the interaction of thymocytes with antibody-forming precursor cells , required in the primary immune response to certain antigens , is mediated by these specific antigen-binding cells of the thymus . | NA | {
"id": "C0018956",
"name": "precursor cells",
"pos": [
72,
87
]
} | {
"id": "C0007634",
"name": "cells",
"pos": [
198,
203
]
} |
in addition a different antigen ( or antigenic determinant ) was shown to be present in one breast carcinoma . | NA | {
"id": "C0003320",
"name": "antigen",
"pos": [
24,
31
]
} | {
"id": "C0003316",
"name": "antigenic determinant",
"pos": [
37,
58
]
} |
although no mucin-secreting cells were detected in the donor carcinoid , the cheek pouch transplants exclusively exhibited mucinsecreting tumour cells of signet-ring type consistent with adenocarcinoma . | NA | {
"id": "C0007095",
"name": "carcinoid",
"pos": [
61,
70
]
} | {
"id": "C0001418",
"name": "adenocarcinoma",
"pos": [
187,
201
]
} |
the role of hemoglobin heme loss in heinz body formation : studies with a partially heme-deficient hemoglobin and with genetically unstable hemoglobins . | NA | {
"id": "C0019046",
"name": "hemoglobin",
"pos": [
12,
22
]
} | {
"id": "C0019016",
"name": "a",
"pos": [
135,
136
]
} |
( d ) heme repletion of the protein molecules by the addition of crystalline hemin to either alpha ( 2 ) ( heme ) beta ( 2 ) ( 0 ) or to the genetically unstable hemoglobins , prevented their precipitation into heinz bodies and normalized their aberrant electrophoretic behaviors ; | NA | {
"id": "C0018988",
"name": "hemin",
"pos": [
77,
82
]
} | {
"id": "C0018966",
"name": "heme",
"pos": [
107,
111
]
} |
transport into the blood in very low density lipoproteins of triglyceride fatty acids derived from free fatty acids was proportional and bore the same relationship to splanchnic uptake of free fatty acids in the two groups . | NA | {
"id": "C0015684",
"name": "fatty acids",
"pos": [
74,
85
]
} | {
"id": "C0015688",
"name": "free fatty acids",
"pos": [
188,
204
]
} |
in normolipemic subjects , near equilibration of specific activities after 4 hr infusion of palmitate-1- ( 14 ) c showed that almost all triglyceride fatty acids of very low density lipoproteins and acetoacetate were derived from free fatty acids taken up in the splanchnic region . | NA | {
"id": "C0015684",
"name": "fatty acids",
"pos": [
150,
161
]
} | {
"id": "C0015688",
"name": "free fatty acids",
"pos": [
230,
246
]
} |
comparison of the rate of equilibration of triglyceride fatty acids- ( 14 ) c with rate of inflow transport from the splanchnic region , together with other data , indicated that most of the circulating triglyceride fatty acids of very low density lipoproteins in hyperlipemic subjects were also derived from free fatty acids . | NA | {
"id": "C0015684",
"name": "fatty acids",
"pos": [
56,
67
]
} | {
"id": "C0015688",
"name": "free fatty acids",
"pos": [
309,
325
]
} |
serial estimations of arterial blood catecholamines after phenoxybenzamine showed an increase of epinephrine and norepinephrine ; | NA | {
"id": "C0014563",
"name": "epinephrine",
"pos": [
97,
108
]
} | {
"id": "C0028351",
"name": "norepinephrine",
"pos": [
113,
127
]
} |
the interaction between na and anionic amino acid influx can be described by the same kinetic model that has been applied to the influxes of neutral amino acids and lysine . | NA | {
"id": "C0002520",
"name": "amino acid",
"pos": [
39,
49
]
} | {
"id": "C0301715",
"name": "neutral amino acids",
"pos": [
141,
160
]
} |
[ fracture of the ulna and of the neck of the radius in a child as a specific form monteggia 's fracture ] . | NA | {
"id": "C0041601",
"name": "fracture of",
"pos": [
2,
13
]
} | {
"id": "C0026508",
"name": "monteggia 's fracture",
"pos": [
83,
104
]
} |
on the biosynthesis of cerebrosides from 2-hydroxy acid ceramides : use of deuterium labeled substrate and multiple ion detector . | NA | {
"id": "C0007805",
"name": "cerebrosides",
"pos": [
23,
35
]
} | {
"id": "C0007745",
"name": "ceramides",
"pos": [
56,
65
]
} |
relationship of antibodies detected by the immunofluorescence method with the various classes of immunoglobulins in cases of untreated syphilis . | NA | {
"id": "C0003241",
"name": "antibodies",
"pos": [
16,
26
]
} | {
"id": "C0021017",
"name": "classes",
"pos": [
86,
93
]
} |
treatment of gonorrhoea with three different antibiotic regimes : doxycycline 300 mg. , procaine penicillin plus benzyl penicillin 2.4 m.u. , benzyl penicillin 5 m.u . plus probenecid . | NA | {
"id": "C0030830",
"name": "procaine",
"pos": [
88,
96
]
} | {
"id": "C0030827",
"name": "benzyl penicillin",
"pos": [
142,
159
]
} |
a formylatable methionine transfer ribonucleic acid from yeast : comparison of coding properties and sequences around the anticodon with escherichia coli formylatable methionine transfer rna . | NA | {
"id": "C0003284",
"name": "anticodon",
"pos": [
122,
131
]
} | {
"id": "C0035711",
"name": "transfer rna",
"pos": [
178,
190
]
} |
individual elution of noradrenaline ( together with adrenaline ) , dopamine , 5-hydroxytryptamine and histamine from a single , strong cation exchange column , by means of mineral acid-organic solvent mixtures . | NA | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
22,
35
]
} | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
52,
62
]
} |
dna-dna hybridization studies between bacterial dna , crown gall tumor cell dna and the normal cell dna . | NA | {
"id": "C0012924",
"name": "bacterial dna",
"pos": [
38,
51
]
} | {
"id": "C0012854",
"name": "dna",
"pos": [
100,
103
]
} |
dna-dna hybridization studies between bacterial dna , crown gall tumor cell dna and the normal cell dna . | NA | {
"id": "C0012930",
"name": "tumor",
"pos": [
65,
70
]
} | {
"id": "C0012854",
"name": "dna",
"pos": [
100,
103
]
} |
[ radioisotopic diagnosis of biliary tract diseases : significance of serial scintiphotography by 131-i-bsp and 131-i-rb in the diagnosis of bile duct and gallbladder diseases ] . | NA | {
"id": "C0005424",
"name": "of biliary tract diseases",
"pos": [
26,
51
]
} | {
"id": "C0016977",
"name": "gallbladder diseases",
"pos": [
155,
175
]
} |
cytotoxic antiserum to theta antigen reduces the capacity of mouse spleen cells to generate direct and indirect plaque-forming cells to sheep erythrocytes in vitro but does not affect plaque-forming cells , their precursors , or hemopoietic stem cells . | NA | {
"id": "C0007634",
"name": "cells",
"pos": [
74,
79
]
} | {
"id": "C0018956",
"name": "hemopoietic",
"pos": [
229,
240
]
} |
optimal conditions were determined for the quantitaion of chicken serum albumin , conalbumin , igg and igm by the radial immunodiffusion test . | NA | {
"id": "C0001924",
"name": "albumin",
"pos": [
72,
79
]
} | {
"id": "C0009629",
"name": "conalbumin",
"pos": [
82,
92
]
} |
the secondary structures of 16s and 23s ribosomal rna 's ( from escherichia coli ) are significantly different from each other and are also different from those of yeast ribosomal rna , formylmethionyl-transfer rna , and the anticodon fragment of this transfer rna . | NA | {
"id": "C0003284",
"name": "anticodon",
"pos": [
225,
234
]
} | {
"id": "C0035711",
"name": "transfer rna",
"pos": [
252,
264
]
} |
high prolactin activity , largely neutralizable with antiserum to human growth hormone , is stimulated along with high immunoassayable growth hormone by insulin-induced hypoglycemia . | NA | {
"id": "C0169964",
"name": "human growth hormone",
"pos": [
66,
86
]
} | {
"id": "C0037663",
"name": "growth",
"pos": [
135,
141
]
} |
to ascertain the distribution of alpha chains within the collagen molecule , intramolecular cross-links were introduced into tropocollagen by reacting formaldehyde with dilute homogeneous molecular dispersions of collagen extracted from lathyritic guinea pig skin . | NA | {
"id": "C0041193",
"name": "tropocollagen",
"pos": [
125,
138
]
} | {
"id": "C0009325",
"name": "collagen",
"pos": [
213,
221
]
} |
plasma lipoprotein alterations in nine insulin-dependent diabetics with hyperlipemia have been related to the lipid accumulating in eruptive xanthomas evolving in these patients . | NA | {
"id": "C0023820",
"name": "lipoprotein",
"pos": [
7,
18
]
} | {
"id": "C0023779",
"name": "lipid",
"pos": [
110,
115
]
} |
these findings , take in conjunction with histochemical and electron microscopic evidence of chylomicron particles in the dermal capillary walls , support the theory that blood lipoproteins , and particularly chylomicrons , permeated the vascular walls and the triglycerides carried by these lipoproteins apparently accumulated in tissue macrophages and perithelial cells which evolved into foam cells . | NA | {
"id": "C0008731",
"name": "chylomicrons",
"pos": [
209,
221
]
} | {
"id": "C0023820",
"name": "lipoproteins",
"pos": [
292,
304
]
} |
the data are compatible with a selective action of corticosteroids on hepatic protein metabolism and with the existence of different mechanisms for the control of albumin and fibrinogen synthesis . | NA | {
"id": "C0033684",
"name": "protein",
"pos": [
78,
85
]
} | {
"id": "C0001924",
"name": "albumin",
"pos": [
163,
170
]
} |
transport of plasma-free fatty acids ( ffa ) and of fatty acids in triglycerides of plasma very low density lipoproteins ( vldl-tgfa ) was studied in two normal subjects , five patients with type iv hyperlipoproteinemia , and two patients with type i hyperlipoproteinemia . | NA | {
"id": "C0015688",
"name": "free fatty acids",
"pos": [
20,
36
]
} | {
"id": "C0015684",
"name": "fatty acids",
"pos": [
52,
63
]
} |
three different multicompartmental models of free fatty acid ( ffa ) and very low density lipoprotein triglyceride fatty acid ( vldl-tgfa ) transport in man are formulated from plasma ffa and vldl-tgfa tracee and tracer data collected over a 24 hr interval after the injection of palmitate- ( 14 ) c . | NA | {
"id": "C0015688",
"name": "ffa",
"pos": [
63,
66
]
} | {
"id": "C0015684",
"name": "vldl-tgfa",
"pos": [
192,
201
]
} |
the positions of this slow compartment are along the hepatic pathway from ffa to vldl-tgfa ( model a ) or in the distribution system of vldl-tgfa ( model b ) or in the distribution system of ffa ( model c ) . | NA | {
"id": "C0015684",
"name": "vldl-tgfa",
"pos": [
81,
90
]
} | {
"id": "C0015688",
"name": "ffa",
"pos": [
191,
194
]
} |
several other models suggesting recycling of plasma vldl-tgfa through the plasma ffa pool , kinetic heterogencity of the plasma vldl-tgfa pool , and contamination of plasma vldl-tgfa radioactivity with low density lipoprotein ( ldl ) tgfa radioactivity were tested . | NA | {
"id": "C0015688",
"name": "ffa",
"pos": [
81,
84
]
} | {
"id": "C0015684",
"name": "vldl-tgfa",
"pos": [
173,
182
]
} |
quantitative differences among the various models are shown by evaluating all of the models with respect to a common set of plasma ffa and vldl-tgfa data . | NA | {
"id": "C0015688",
"name": "ffa",
"pos": [
131,
134
]
} | {
"id": "C0015684",
"name": "vldl-tgfa",
"pos": [
139,
148
]
} |
the plasma low density lipoproteins ( ldl ) in biliary obstruction are characterized almost exclusively by the presence of the immunochemically distinct lipoprotein families , lipoprotein b ( lp-b ) and lipoprotein x ( lp-x ) . | NA | {
"id": "C0023820",
"name": "lipoprotein",
"pos": [
23,
34
]
} | {
"id": "C0023819",
"name": "lipoprotein x",
"pos": [
203,
216
]
} |
to show their protein moieties , we isolated lp-x and lp-b from the ldl in plasma obtained from patients with obstructive jaundice . | NA | {
"id": "C0023819",
"name": "lp-x",
"pos": [
45,
49
]
} | {
"id": "C0023820",
"name": "lp-b",
"pos": [
54,
58
]
} |
whereas lp-b was characterized by the presence of apolipoprotein b ( apob ) , intact lp-x contained a protein moiety of unique composition consisting of a mixture of albumin ( approximately 40 % ) and the specific apolipoprotein , apox ( 60 % ) . | NA | {
"id": "C0023820",
"name": "lp-b",
"pos": [
8,
12
]
} | {
"id": "C0023819",
"name": "lp-x",
"pos": [
85,
89
]
} |
whereas lp-b was characterized by the presence of apolipoprotein b ( apob ) , intact lp-x contained a protein moiety of unique composition consisting of a mixture of albumin ( approximately 40 % ) and the specific apolipoprotein , apox ( 60 % ) . | NA | {
"id": "C0003593",
"name": "apolipoprotein b",
"pos": [
50,
66
]
} | {
"id": "C0003591",
"name": "apolipoprotein",
"pos": [
214,
228
]
} |
lp-x thus comprises an albumin-lipoprotein complex in which the masked antigenic site of albumin can be revealed by partial or total delipidization . | NA | {
"id": "C0023819",
"name": "lp-x",
"pos": [
0,
4
]
} | {
"id": "C0023820",
"name": "lipoprotein",
"pos": [
31,
42
]
} |
apolipoprotein x , the characteristic nonalbumin protein moiety of intact or partially delipidized lp-x , was immunochemically different from apoa , apob , albumin , gamma-globulins , and other serum proteins . | NA | {
"id": "C0003591",
"name": "apolipoprotein",
"pos": [
0,
14
]
} | {
"id": "C0003592",
"name": "apoa",
"pos": [
142,
146
]
} |
apolipoprotein x , the characteristic nonalbumin protein moiety of intact or partially delipidized lp-x , was immunochemically different from apoa , apob , albumin , gamma-globulins , and other serum proteins . | NA | {
"id": "C0003591",
"name": "apolipoprotein",
"pos": [
0,
14
]
} | {
"id": "C0003593",
"name": "apob",
"pos": [
149,
153
]
} |
apolipoprotein x , the characteristic nonalbumin protein moiety of intact or partially delipidized lp-x , was immunochemically different from apoa , apob , albumin , gamma-globulins , and other serum proteins . | NA | {
"id": "C0033684",
"name": "protein",
"pos": [
7,
14
]
} | {
"id": "C0001924",
"name": "albumin",
"pos": [
156,
163
]
} |
apox was characterized by its amino acid composition , and by serine and threonine as the major n-terminal and alanine as the major c-terminal amino acids . | NA | {
"id": "C0002520",
"name": "amino acid",
"pos": [
30,
40
]
} | {
"id": "C0001898",
"name": "alanine",
"pos": [
111,
118
]
} |
transfer of amino acids from aminoacyl-trna into protein by isolated ribosomes of the house cricket . | NA | {
"id": "C0002520",
"name": "amino acids",
"pos": [
12,
23
]
} | {
"id": "C0035714",
"name": "aminoacyl-trna",
"pos": [
29,
43
]
} |
compared with isoxazole penicillins in current clinical use-namely , oxacillin , cloxacillin , and dicloxacillin-flucloxacillin has proved as active against gram-positive cocci , including penicillin-resistant staphylococci . | NA | {
"id": "C0030842",
"name": "penicillins",
"pos": [
24,
35
]
} | {
"id": "C0029983",
"name": "oxacillin",
"pos": [
118,
127
]
} |
compared with isoxazole penicillins in current clinical use-namely , oxacillin , cloxacillin , and dicloxacillin-flucloxacillin has proved as active against gram-positive cocci , including penicillin-resistant staphylococci . | NA | {
"id": "C0029983",
"name": "oxacillin",
"pos": [
69,
78
]
} | {
"id": "C0009077",
"name": "cloxacillin",
"pos": [
116,
127
]
} |
compared with isoxazole penicillins in current clinical use-namely , oxacillin , cloxacillin , and dicloxacillin-flucloxacillin has proved as active against gram-positive cocci , including penicillin-resistant staphylococci . | NA | {
"id": "C0009077",
"name": "cloxacillin",
"pos": [
81,
92
]
} | {
"id": "C0012093",
"name": "dicloxacillin",
"pos": [
99,
112
]
} |
compared with isoxazole penicillins in current clinical use-namely , oxacillin , cloxacillin , and dicloxacillin-flucloxacillin has proved as active against gram-positive cocci , including penicillin-resistant staphylococci . | NA | {
"id": "C0009077",
"name": "cloxacillin",
"pos": [
81,
92
]
} | {
"id": "C0016267",
"name": "flucloxacillin",
"pos": [
113,
127
]
} |
the extent of binding of flucloxacillin to the protein of human serum was similar to that of oxacillin and cloxacillin and less than that of dicloxacillin . | NA | {
"id": "C0016267",
"name": "flucloxacillin",
"pos": [
25,
39
]
} | {
"id": "C0009077",
"name": "cloxacillin",
"pos": [
143,
154
]
} |
the extent of binding of flucloxacillin to the protein of human serum was similar to that of oxacillin and cloxacillin and less than that of dicloxacillin . | NA | {
"id": "C0029983",
"name": "oxacillin",
"pos": [
30,
39
]
} | {
"id": "C0009077",
"name": "cloxacillin",
"pos": [
143,
154
]
} |
the extent of binding of flucloxacillin to the protein of human serum was similar to that of oxacillin and cloxacillin and less than that of dicloxacillin . | NA | {
"id": "C0009077",
"name": "cloxacillin",
"pos": [
28,
39
]
} | {
"id": "C0012093",
"name": "dicloxacillin",
"pos": [
141,
154
]
} |
in man flucloxacillin given orally produced total and free serum levels higher than those obtained with oxacillin and cloxacillin ; | NA | {
"id": "C0016267",
"name": "flucloxacillin",
"pos": [
7,
21
]
} | {
"id": "C0009077",
"name": "cloxacillin",
"pos": [
118,
129
]
} |
in man flucloxacillin given orally produced total and free serum levels higher than those obtained with oxacillin and cloxacillin ; | NA | {
"id": "C0029983",
"name": "oxacillin",
"pos": [
12,
21
]
} | {
"id": "C0009077",
"name": "cloxacillin",
"pos": [
118,
129
]
} |
similarly , after intramuscular injection the free serum levels of flucloxacillin were higher than those of oxacillin , cloxacillin , and dicloxacillin . | NA | {
"id": "C0016267",
"name": "flucloxacillin",
"pos": [
67,
81
]
} | {
"id": "C0009077",
"name": "cloxacillin",
"pos": [
140,
151
]
} |
similarly , after intramuscular injection the free serum levels of flucloxacillin were higher than those of oxacillin , cloxacillin , and dicloxacillin . | NA | {
"id": "C0029983",
"name": "oxacillin",
"pos": [
72,
81
]
} | {
"id": "C0009077",
"name": "cloxacillin",
"pos": [
140,
151
]
} |
similarly , after intramuscular injection the free serum levels of flucloxacillin were higher than those of oxacillin , cloxacillin , and dicloxacillin . | NA | {
"id": "C0009077",
"name": "cloxacillin",
"pos": [
70,
81
]
} | {
"id": "C0012093",
"name": "dicloxacillin",
"pos": [
138,
151
]
} |
a new amino acid , which is chemically related to bacilysin , was isolated from the fraction containing neutral amino acids . | NA | {
"id": "C0002520",
"name": "amino acid",
"pos": [
6,
16
]
} | {
"id": "C0301715",
"name": "neutral amino acids",
"pos": [
104,
123
]
} |
[ effect of histamine , carbachol , pentagastrin and chick gastrin extracts on gastric secretion of unanesthetized chickens with a gastric fistula ] . | NA | {
"id": "C0030859",
"name": "pentagastrin",
"pos": [
36,
48
]
} | {
"id": "C0017151",
"name": "gastrin",
"pos": [
59,
66
]
} |
unique among adenine nucleotides tested by filter binding assays , 3':5'-cyclic amp binds to the g translocation factor . | NA | {
"id": "C0001413",
"name": "adenine nucleotides",
"pos": [
13,
32
]
} | {
"id": "C0001455",
"name": "cyclic",
"pos": [
73,
79
]
} |
the morphology of the cells is altered , such that the cells grow in a flattened , often fibroblastic monolayer , showing contact inhibition , instead of the rounded , multilayered mounds characteristic of the line . | NA | {
"id": "C0007634",
"name": "cells",
"pos": [
22,
27
]
} | {
"id": "C0016030",
"name": "fibroblastic",
"pos": [
89,
101
]
} |
this lp ( a ) antigen was demonstrated by gel diffusion to be indistinguishable from lp-lipoprotein isolated from known lp ( a+ ) sera . | NA | {
"id": "C0023820",
"name": "lipoprotein",
"pos": [
88,
99
]
} | {
"id": "C0065058",
"name": "lp ( a",
"pos": [
5,
11
]
} |
the lp ( a ) preparations from sera classified lp ( a- ) also showed electrophoretic mobility in immunoelectrophoresis and schlieren diagrams in ultracentrifugal analyses similar to lp-lipoprotein from lp ( a+ ) sera . | NA | {
"id": "C0023820",
"name": "lipoprotein",
"pos": [
185,
196
]
} | {
"id": "C0065058",
"name": "lp ( a",
"pos": [
4,
10
]
} |
when deprived of water hamsters reared from birth without access to drinking water licked cold metal in preference to metal maintained at room or body temperature . | NA | {
"id": "C0043047",
"name": "water",
"pos": [
17,
22
]
} | {
"id": "C0599638",
"name": "drinking water",
"pos": [
68,
82
]
} |
[ dynamics of the antibody response to streptococcal antigens in spontaneous group a beta-hemolytic streptococcus infections ( scarlet fever ) ] . | NA | {
"id": "C0038395",
"name": "streptococcal",
"pos": [
39,
52
]
} | {
"id": "C0036285",
"name": "scarlet fever",
"pos": [
127,
140
]
} |
causes of damage to tissues by polymers and elastomers used in the fabrication of tracheal devices . | NA | {
"id": "C0032521",
"name": "polymers",
"pos": [
31,
39
]
} | {
"id": "C0013766",
"name": "elastomers",
"pos": [
44,
54
]
} |
competition between leucine and phenylalanine and its relation to p-fluorophenylalanine resistant mutations in aspergillus nidulans . | NA | {
"id": "C0031453",
"name": "phenylalanine",
"pos": [
32,
45
]
} | {
"id": "C0030137",
"name": "p-fluorophenylalanine",
"pos": [
66,
87
]
} |
roles of subunit interactions and of intermediate structures in the cooperative oxygenation of hemoglobin and the results of hemoglobin yakima , hemoglobin j capetown , and carboxypeptidases a and b treated hemoglobin a . | NA | {
"id": "C0019046",
"name": "hemoglobin",
"pos": [
95,
105
]
} | {
"id": "C0019016",
"name": "hemoglobin a",
"pos": [
207,
219
]
} |
[ catecholamines and obesity . ( study of the differences of excretion of adrenaline and noradrenaline found in relation to android and gynoid types ) ] . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
74,
84
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
89,
102
]
} |
[ surgical therapy of jaw deformities caused by cleft lip and cleft palate . indications and late results ] . | NA | {
"id": "C0022360",
"name": "jaw deformities",
"pos": [
22,
37
]
} | {
"id": "C0008925",
"name": "cleft palate",
"pos": [
62,
74
]
} |
clones of two lines , ls-b and eb ( 3 ) , which contain epstein-barr viral ( ebv ) antigen in approximately 1 % of cells were tested for ebv antigen . | NA | {
"id": "C0003342",
"name": "viral",
"pos": [
69,
74
]
} | {
"id": "C0003320",
"name": "antigen",
"pos": [
141,
148
]
} |
[ studies on guinea pig antiserum against human gastric intrinsic factor , with special reference to its serological similarities to human anti-if antibody ] . | NA | {
"id": "C0020960",
"name": "antiserum",
"pos": [
24,
33
]
} | {
"id": "C0003241",
"name": "antibody",
"pos": [
147,
155
]
} |
[ influence exerted by the diet contents in proteins or certain amino acids ( sulphur amino acids or valine ) on the morphology of lymphocytes in the rat intestinal mucosa ] . | NA | {
"id": "C0002520",
"name": "amino acids",
"pos": [
64,
75
]
} | {
"id": "C0002527",
"name": "sulphur amino acids",
"pos": [
78,
97
]
} |
[ effect on serum lipids and body growth of a special type of milk with partial replacement of lipids by vegetable fats ] . | NA | {
"id": "C0023779",
"name": "lipids",
"pos": [
18,
24
]
} | {
"id": "C0015677",
"name": "fats",
"pos": [
115,
119
]
} |
in labelling studies with [ ( 14 ) c ] proline in vitro , the specific radioactivities of neutral-soluble , acid-soluble and insoluble collagens in rat liver were found to be 233000 , 69000 and 830d.p.m./mumol of hydroxyproline respectively after 1h . | NA | {
"id": "C0033382",
"name": "proline",
"pos": [
39,
46
]
} | {
"id": "C0020388",
"name": "hydroxyproline",
"pos": [
213,
227
]
} |
the presence of free fatty acid was necessary for the maximal hydrolysis of lecithin ( phosphatidylcholine ) , but there was no accumulation of lysolecithin ( 1 or 2-acylglycerophosphorylcholine ) ; lysolecithin accumulated when the reaction was carried out in the presence of sodium deoxycholate and at or above ph8.0 . | NA | {
"id": "C0031617",
"name": "lecithin",
"pos": [
76,
84
]
} | {
"id": "C1959616",
"name": "phosphatidylcholine",
"pos": [
87,
106
]
} |
atp and coa were necessary for the incorporation of free [ 1- ( 14 ) c ] oleic acid into lecithin ( phosphatidylcholine ) . | NA | {
"id": "C0031617",
"name": "lecithin",
"pos": [
89,
97
]
} | {
"id": "C1959616",
"name": "phosphatidylcholine",
"pos": [
100,
119
]
} |
the electrophoretic patterns given by the proteins of the chromaffin granule membrane were distinct from those given by the chromogranins , and from those given by mitochondrial and microsomal membrane proteins . | NA | {
"id": "C0033684",
"name": "proteins",
"pos": [
42,
50
]
} | {
"id": "C0025252",
"name": "membrane proteins",
"pos": [
193,
210
]
} |
glutamic acid , glycine , proline and hydroxyproline made up about 54 % by weight of the amino acids obtained on acid hydrolysis . | NA | {
"id": "C0017890",
"name": "glycine",
"pos": [
16,
23
]
} | {
"id": "C0002520",
"name": "amino acids",
"pos": [
89,
100
]
} |
glutamic acid , glycine , proline and hydroxyproline made up about 54 % by weight of the amino acids obtained on acid hydrolysis . | NA | {
"id": "C0033382",
"name": "proline",
"pos": [
26,
33
]
} | {
"id": "C0020388",
"name": "hydroxyproline",
"pos": [
38,
52
]
} |
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