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moreover , duplex doppler sonography play an important role in the evaluation of renal hemodynamics , especially in kidney transplants . | target_anatomy_has_procedure | {
"id": "C0022646",
"name": "renal",
"pos": [
81,
86
]
} | {
"id": "C0022671",
"name": "kidney transplants",
"pos": [
116,
134
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} |
this variation in anatomic relationship between the cfa and cfv is clinically significant , since a femoral vein puncture can be associated with simultaneous passage of the entry needle through the artery and thus formation of an arteriovenous fistula . | target_anatomy_has_procedure | {
"id": "C0003842",
"name": "artery",
"pos": [
198,
204
]
} | {
"id": "C0684204",
"name": "formation of",
"pos": [
214,
226
]
} |
special compression views of the breast were used to detect suspect lesions in eight women who had undergone augmentation mammoplasty . | target_anatomy_has_procedure | {
"id": "C0006141",
"name": "breast",
"pos": [
33,
39
]
} | {
"id": "C0191925",
"name": "augmentation mammoplasty",
"pos": [
109,
133
]
} |
in these cases , complete excision of the ring and end-to-end anastomosis of the gastric and esophageal mucosa through a gastrostomy is recommended before antireflux surgery is considered . | target_anatomy_has_procedure | {
"id": "C0038351",
"name": "gastric",
"pos": [
81,
88
]
} | {
"id": "C0017196",
"name": "gastrostomy",
"pos": [
121,
132
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} |
contralateral neck node metastasis has been identified as a significant factor in neck failures in those patients undergoing simultaneous prophylactic neck dissection . | target_anatomy_has_procedure | {
"id": "C0027530",
"name": "neck",
"pos": [
14,
18
]
} | {
"id": "C0398395",
"name": "neck",
"pos": [
151,
155
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} |
they were related to a pre-operative interval of more than 10 hours , severity of colonic lesion ( cis ) grade iii to v , blood transfusion of more than 2500 ml , the presence of colostomy , and an abdominal trauma index ( pati ) of more than 25 . | target_anatomy_has_procedure | {
"id": "C0009368",
"name": "colonic",
"pos": [
82,
89
]
} | {
"id": "C0009410",
"name": "colostomy",
"pos": [
179,
188
]
} |
the patients completed a questionnaire and the breasts were judged according to a new breast augmentation classification ( bac ) scale . | target_anatomy_has_procedure | {
"id": "C0006141",
"name": "breasts",
"pos": [
47,
54
]
} | {
"id": "C0191925",
"name": "breast augmentation",
"pos": [
86,
105
]
} |
in elective patients , repeated x-ray examinations of the colon , especially with air contrast barium enema and colonoscopy , are recommended to distinguish benign cecal ulceration from a malignancy . | target_anatomy_has_procedure | {
"id": "C0009368",
"name": "colon",
"pos": [
58,
63
]
} | {
"id": "C0009378",
"name": "colonoscopy",
"pos": [
112,
123
]
} |
plasma clearance of inulin ( cin ) , 99mtc-dtpa ( cdtpa ) , and urographic contrast media ( ccm ) were determined simultaneously in 31 patients with varying levels of renal function evaluated in the setting of affiliated cardiac and renal transplantation programs . | target_anatomy_has_procedure | {
"id": "C0022646",
"name": "renal",
"pos": [
167,
172
]
} | {
"id": "C0022671",
"name": "renal",
"pos": [
233,
238
]
} |
to investigate the antiischemic efficacy of intravenously administered diltiazem , 42 patients were randomly allocated to receive placebo or active treatment before 1-vessel percutaneous transluminal coronary angioplasty ( ptca ) . | target_anatomy_has_procedure | {
"id": "C0005847",
"name": "vessel",
"pos": [
167,
173
]
} | {
"id": "C2936173",
"name": "percutaneous transluminal coronary angioplasty",
"pos": [
174,
220
]
} |
purpose : we sought to determine the presence of the parasite cryptosporidium in the duodenal aspirates of patients undergoing routine upper gastrointestinal endoscopy . | target_anatomy_has_procedure | {
"id": "C0013303",
"name": "duodenal",
"pos": [
85,
93
]
} | {
"id": "C0079304",
"name": "upper gastrointestinal",
"pos": [
135,
157
]
} |
the visual acuity improved after cryotherapy in one eye , and in two eyes visual improvement occurred after vitrectomy and membrane removal . | target_anatomy_has_procedure | {
"id": "C0015392",
"name": "eye",
"pos": [
52,
55
]
} | {
"id": "C0042903",
"name": "vitrectomy",
"pos": [
108,
118
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} |
sternal subcutaneous tissue and marrow concentrations were respectively 24.4 +/- 13.3 micrograms.g-1 and 31 +/- 5.6 micrograms.g-1 at the time of sternotomy , and 9.4 +/- 5.5 micrograms.g-1 and 9.2 +/- 3.5 micrograms.g-1 at the end of the procedure . | target_anatomy_has_procedure | {
"id": "C0038293",
"name": "sternal",
"pos": [
0,
7
]
} | {
"id": "C0185792",
"name": "sternotomy",
"pos": [
146,
156
]
} |
the sensitivity of bladder wash flow cytometry ( bwfcm ) , voided urinary cytology ( vuc ) , and cytology of catheterized urine obtained at the time of cystoscopy ( cuc ) were reviewed on all women evaluated for bladder cancer at memorial sloan-kettering cancer center between june 1985 and december 1986 . | target_anatomy_has_procedure | {
"id": "C0005682",
"name": "bladder",
"pos": [
19,
26
]
} | {
"id": "C0010702",
"name": "cystoscopy",
"pos": [
152,
162
]
} |
the resected livers obtained from two groups of patients who received liver transplants between 1983 and 1987 at the university of pittsburgh were examined : group a consisted of 11 patients who were not treated ( controls ) , and group b consisted of 10 patients ( experimental group ) who were treated with ifn-alpha for 29.4 +/- 5.6 days prior to transplantation . | target_anatomy_has_procedure | {
"id": "C0023884",
"name": "livers",
"pos": [
13,
19
]
} | {
"id": "C0023911",
"name": "liver transplants",
"pos": [
70,
87
]
} |
[ endocrine control of iron metabolism . vii . action of castration on blood iron in rabbits of both sexes ] . | target_anatomy_has_procedure | {
"id": "C0014136",
"name": "endocrine",
"pos": [
2,
11
]
} | {
"id": "C0007344",
"name": "castration",
"pos": [
57,
67
]
} |
the effectiveness of computerized renal angioscintigraphy with 99m-tc-dtpa and ultrasound in the differential diagnosis of complications after kidney transplant was evaluated . | target_anatomy_has_procedure | {
"id": "C0022646",
"name": "renal",
"pos": [
34,
39
]
} | {
"id": "C0022671",
"name": "kidney",
"pos": [
143,
149
]
} |
all dogs with a presumptive diagnosis of gastric volvulus were treated surgically by gastric derotation and gastrostomy on an emergency basis . | target_anatomy_has_procedure | {
"id": "C0038351",
"name": "gastric",
"pos": [
41,
48
]
} | {
"id": "C0017196",
"name": "gastrostomy",
"pos": [
108,
119
]
} |
epithelial cells were not stained in 6 normal mammary glands collected during reduction mammoplasties and in 9 normal uteri , whether tissues were collected during the follicular or luteal phase . | target_anatomy_has_procedure | {
"id": "C0929301",
"name": "mammary glands",
"pos": [
46,
60
]
} | {
"id": "C0191922",
"name": "reduction mammoplasties",
"pos": [
78,
101
]
} |
the use of us is dependent on the presence of an acoustic window in the skull after craniotomy . | target_anatomy_has_procedure | {
"id": "C0037303",
"name": "skull",
"pos": [
72,
77
]
} | {
"id": "C0010280",
"name": "craniotomy",
"pos": [
84,
94
]
} |
hyperacute rejection , which is a complication of organ allografts in some immunological situations , has not been observed after liver transplantation . | target_anatomy_has_procedure | {
"id": "C0178784",
"name": "organ",
"pos": [
50,
55
]
} | {
"id": "C0023911",
"name": "liver transplantation",
"pos": [
130,
151
]
} |
the cardiovascular effects of dilazep , a new antianginal drug , were investigated in 18 patients , who underwent cardiac catheterization and coronary angiography for the evaluation of chest pain . | target_anatomy_has_procedure | {
"id": "C0007226",
"name": "cardiovascular",
"pos": [
4,
18
]
} | {
"id": "C0018795",
"name": "cardiac catheterization",
"pos": [
114,
137
]
} |
from july 1971 to august 1981 , 31 selected patients with t1 , t2 tumours of the tonsillar region were treated according to the following protocol : telecobalt therapy to the primary site and to neck nodes to a dose of 45 gy , brachytherapy to the primary site to a dose of 25-30 gy using iridium 192 , boost dose to involved neck nodes , with electrons , or radical neck dissection , wether n1 , n2 or n3 . | target_anatomy_has_procedure | {
"id": "C0027530",
"name": "neck",
"pos": [
195,
199
]
} | {
"id": "C0034542",
"name": "radical neck dissection",
"pos": [
359,
382
]
} |
four hundred ten eyes with retinal detachment and proliferative vitreoretinopathy underwent closed vitrectomy with membrane peeling , scleral buckling , and intraocular air injection . | target_anatomy_has_procedure | {
"id": "C0015392",
"name": "eyes",
"pos": [
17,
21
]
} | {
"id": "C0042903",
"name": "vitrectomy",
"pos": [
99,
109
]
} |
a case-control retrospective evaluation of vitrectomy in penetrating ocular trauma was performed by matching 89 eyes , managed with vitrectomy , with 89 similar eyes that did not undergo vitrectomy . | target_anatomy_has_procedure | {
"id": "C0015392",
"name": "eyes",
"pos": [
112,
116
]
} | {
"id": "C0042903",
"name": "vitrectomy",
"pos": [
187,
197
]
} |
a case of renal artery stenosis due to compression by a neurofibrous cord ( histologically a pheochromocytoma ) and resolved by the debridment of the vessel and angioplasty with a patch in the saphenous vein , is reported . | target_anatomy_has_procedure | {
"id": "C0005847",
"name": "vessel",
"pos": [
150,
156
]
} | {
"id": "C0162577",
"name": "angioplasty",
"pos": [
161,
172
]
} |
[ structural modifications of the mammary gland function following obstruction of the excretory ducts in relation to various mastoplastic technics : experimental studies ] . | target_anatomy_has_procedure | {
"id": "C0929301",
"name": "mammary gland",
"pos": [
34,
47
]
} | {
"id": "C0085076",
"name": "mastoplastic",
"pos": [
125,
137
]
} |
androgens appear to be an effective sequential endocrine treatment of stage iv breast cancer after tamoxifen and hypophysectomy . | target_anatomy_has_procedure | {
"id": "C0014136",
"name": "endocrine",
"pos": [
47,
56
]
} | {
"id": "C0020632",
"name": "hypophysectomy",
"pos": [
113,
127
]
} |
it was concluded that double-contrast radiography is the radiological method of choice in suspected reflux esophagitis , and that screening of the lower esophagus should be included in examinations of the upper gastrointestinal tract . | target_anatomy_has_procedure | {
"id": "C0014876",
"name": "esophagus",
"pos": [
153,
162
]
} | {
"id": "C0079304",
"name": "examinations",
"pos": [
185,
197
]
} |
in this retrospective study , the value of tsc uptake in diagnosing renal rejection was studied in different time intervals after renal transplantation . | target_anatomy_has_procedure | {
"id": "C0022646",
"name": "renal",
"pos": [
68,
73
]
} | {
"id": "C0022671",
"name": "renal transplantation",
"pos": [
130,
151
]
} |
we have found a good correlation between the presence of progressive retinal neovascularization in an eye and the ability of vitreous cavity fluid from that eye ( obtained at the time of vitrectomy ) to stimulate vascular endothelial cell migration in vitro . | target_anatomy_has_procedure | {
"id": "C0015392",
"name": "eye",
"pos": [
102,
105
]
} | {
"id": "C0042903",
"name": "vitrectomy",
"pos": [
187,
197
]
} |
if the clinical syndrome of the dissociated cerebral death is present , without planned taking off an organ there is no necessity to render the finish of the intensive therapy dependent on legal regulations concerning the performance of organ transplantations . | target_anatomy_has_procedure | {
"id": "C0178784",
"name": "organ",
"pos": [
102,
107
]
} | {
"id": "C0029216",
"name": "organ",
"pos": [
237,
242
]
} |
seventy-four percent of mannitol , 100 % of lactulose , and 88 % of raffinose passed unabsorbed through the small intestine of six patients with ileostomies . | target_anatomy_has_procedure | {
"id": "C0021852",
"name": "small intestine",
"pos": [
108,
123
]
} | {
"id": "C0020883",
"name": "ileostomies",
"pos": [
145,
156
]
} |
the enormous cost and the services necessary to provide this attention in view of the relatively poor survival rates of tissue and organ grafts in dogs will continue to prevent organ transplantation becoming a reality in veterinary practice . | target_anatomy_has_procedure | {
"id": "C0178784",
"name": "organ",
"pos": [
131,
136
]
} | {
"id": "C0029216",
"name": "organ",
"pos": [
177,
182
]
} |
effected originally as a first step in eyes undergoing vitrectomy , when an opaque lens interfered with fundus visibility , it has started to be used as an independant procedure in the case of soft-mostly traumatic-cataracts , and in that of ectopic or subluxated lenses . | target_anatomy_has_procedure | {
"id": "C0015392",
"name": "eyes",
"pos": [
39,
43
]
} | {
"id": "C0042903",
"name": "vitrectomy",
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55,
65
]
} |
high-density-lipoprotein cholesterol concentrations in both groups of renal patients were significantly lower than control values ( p less than 0.01 ) , and their ratios of low-density-lipoprotein to high-density-lipoprotein cholesterol were significantly higher ( p less than 0.01 ) than those observed in both randomly selected controls and in controls matched for plasma lipid levels ( control , 2.4 +/- 1.2 , dialysis , 3.7 +/- 2.1 , and transplant , 5.4 +/- 2.3 mg per 100 ml [ mean +/- s.d . ] ) if , as experimental evidence suggests , high-density lipoprotein retards the development of atherosclerosis , and low-density lipoprotein has opposite effects , the higher ratio of low-density-lipoprotein to high-density-lipoprotein cholesterol found in chronic-dialysis and renal-transplant patients may be related to their premature morbidity and mortality from cardiovascular causes . | target_anatomy_has_procedure | {
"id": "C0022646",
"name": "renal",
"pos": [
70,
75
]
} | {
"id": "C0022671",
"name": "renal-transplant",
"pos": [
778,
794
]
} |
in a consecutive series of 174 patients the biliary and pancreatic ducts were demonstrated by endoscopic retrograde cholangio-pancreatography ( ercp ) . | target_anatomy_has_procedure | {
"id": "C0030288",
"name": "pancreatic ducts",
"pos": [
56,
72
]
} | {
"id": "C0008310",
"name": "ercp",
"pos": [
144,
148
]
} |
young patients with rheumatoid arthritis and other chronic diseases of the skeleton are increasingly being operated on with replacement of major joints . | target_anatomy_has_procedure | {
"id": "C0037253",
"name": "skeleton",
"pos": [
75,
83
]
} | {
"id": "C0185317",
"name": "replacement of",
"pos": [
124,
138
]
} |
thirteen eyes with opaque media and a triangular retinal detachment by ultrasound had severe mpp at vitrectomy or enucleation . | target_anatomy_has_procedure | {
"id": "C0015392",
"name": "eyes",
"pos": [
9,
13
]
} | {
"id": "C0042903",
"name": "vitrectomy",
"pos": [
100,
110
]
} |
eyes with this type of retinal detachment have a poor surgical prognosis even with modern vitrectomy techniques . | target_anatomy_has_procedure | {
"id": "C0015392",
"name": "eyes",
"pos": [
0,
4
]
} | {
"id": "C0042903",
"name": "vitrectomy",
"pos": [
90,
100
]
} |
six cases of severe salmonella genitourinary infection and a case of salmonella septicemia after prostatectomy are reported . | target_anatomy_has_procedure | {
"id": "C0042066",
"name": "genitourinary",
"pos": [
31,
44
]
} | {
"id": "C0033573",
"name": "prostatectomy",
"pos": [
97,
110
]
} |
due to the significant relation between restrictions of the renal blood-supply and the renal function after transplantation haemodynamic parameters are suitable for the judgment of renal preservation methods and for the prognostic estimation of renal grafts . | target_anatomy_has_procedure | {
"id": "C0022646",
"name": "renal",
"pos": [
60,
65
]
} | {
"id": "C0022671",
"name": "renal grafts",
"pos": [
245,
257
]
} |
treatment should consist of relief of any obstruction to the duodenum by a bypass gastrojejunostomy is recommeded in those cases having associated peptic ulcer . | target_anatomy_has_procedure | {
"id": "C0013303",
"name": "duodenum",
"pos": [
61,
69
]
} | {
"id": "C0399839",
"name": "gastrojejunostomy",
"pos": [
82,
99
]
} |
seven eyes and one vitrectomy specimen from seven patients with pars planitis and complications such as secondary glaucoma and phthisis bulbi were studied histopathologically . | target_anatomy_has_procedure | {
"id": "C0015392",
"name": "eyes",
"pos": [
6,
10
]
} | {
"id": "C0042903",
"name": "vitrectomy",
"pos": [
19,
29
]
} |
when bleeding and the pancreatic inflammatory process involved the colon , ligation of the bleeding site , drainage of the area , and colostomy was the most successful form of treatment . | target_anatomy_has_procedure | {
"id": "C0009368",
"name": "colon",
"pos": [
67,
72
]
} | {
"id": "C0009410",
"name": "colostomy",
"pos": [
134,
143
]
} |
when bleeding has been demonstrated to originate from the colon , colonoscopic examination should be performed . | target_anatomy_has_procedure | {
"id": "C0009368",
"name": "colon",
"pos": [
58,
63
]
} | {
"id": "C0009378",
"name": "colonoscopic",
"pos": [
66,
78
]
} |
these results suggest that the total liver blood flow in combination with the functional state of the remaining recipient liver , rather than the quality of venous blood deriving from certain splanchnic areas and/or peculiar factor convoyed with it , determines the survival of a liver graft . | target_anatomy_has_procedure | {
"id": "C0023884",
"name": "liver",
"pos": [
37,
42
]
} | {
"id": "C0023911",
"name": "liver graft",
"pos": [
280,
291
]
} |
arteriovenous fistulae in renal allograft are rarely mentioned in papers dealing with vascular complications after renal transplantations . | target_anatomy_has_procedure | {
"id": "C0022646",
"name": "renal",
"pos": [
26,
31
]
} | {
"id": "C0022671",
"name": "renal transplantations",
"pos": [
115,
137
]
} |
the role of bile acids in determining ileal flow rates in normal subjects and following ileostomy . | target_anatomy_has_procedure | {
"id": "C0020885",
"name": "flow rates",
"pos": [
44,
54
]
} | {
"id": "C0020883",
"name": "ileostomy",
"pos": [
88,
97
]
} |
after an analysis of the literature , the author reflects on the problem to what extent the ophtalmologist can at present assess , based on a post-mortem examination of the ocular fundus , the time of death in cases where a team of specialists decides whether resuscitation may be terminated after clinical death of a patient where an organ is foreseen for transplantation , and in forensic and criminal medicine some time after death . | target_anatomy_has_procedure | {
"id": "C0178784",
"name": "organ",
"pos": [
335,
340
]
} | {
"id": "C0029216",
"name": "transplantation",
"pos": [
357,
372
]
} |
to determine the effect of an acute dose of ethanol on the stomach and duodenum , seven alcoholic subjects with previously normal upper gastrointestinal endoscopy were reevaluated with endoscopy and directed biopsy three hours after the oral ingestion of ethanol ( 1 gm./kg . body weight ) as a 35 gm./100 ml . solution . | target_anatomy_has_procedure | {
"id": "C0038351",
"name": "stomach",
"pos": [
59,
66
]
} | {
"id": "C0079304",
"name": "upper gastrointestinal endoscopy",
"pos": [
130,
162
]
} |
to determine the effect of an acute dose of ethanol on the stomach and duodenum , seven alcoholic subjects with previously normal upper gastrointestinal endoscopy were reevaluated with endoscopy and directed biopsy three hours after the oral ingestion of ethanol ( 1 gm./kg . body weight ) as a 35 gm./100 ml . solution . | target_anatomy_has_procedure | {
"id": "C0013303",
"name": "duodenum",
"pos": [
71,
79
]
} | {
"id": "C0079304",
"name": "upper gastrointestinal endoscopy",
"pos": [
130,
162
]
} |
the results indicate that estimation of net lactate exchange across the heart can be of value in assessing the viability of myocardium following coronary bypass surgery . | target_anatomy_has_procedure | {
"id": "C0018787",
"name": "heart",
"pos": [
72,
77
]
} | {
"id": "C0010055",
"name": "coronary bypass surgery",
"pos": [
145,
168
]
} |
to assess the multiple risk factors reported to be associated with onset of serious bacterial , fungal , viral , and protozoal infections in renal allograft recipients , a retrospective study of all renal transplantations performed at yale-new haven medical center from the inception of the transplantation program in december , 1967 , to december , 1975 , was undertaken . | target_anatomy_has_procedure | {
"id": "C0022646",
"name": "renal",
"pos": [
141,
146
]
} | {
"id": "C0022671",
"name": "renal transplantations",
"pos": [
199,
221
]
} |
serial histologic effects of rat submaxillary and sublingual salivary gland duct and blood vessel ligation . | target_anatomy_has_procedure | {
"id": "C0005847",
"name": "blood vessel",
"pos": [
85,
97
]
} | {
"id": "C0023690",
"name": "ligation",
"pos": [
98,
106
]
} |
[ characteristics of splenic circulation in various experimental conditions ( hyperhemolysis , vascular ligation , histamine shock ) demonstrated by casts made by injection of latex 571 and subsequent corrosion ] . | target_anatomy_has_procedure | {
"id": "C0005847",
"name": "vascular",
"pos": [
95,
103
]
} | {
"id": "C0023690",
"name": "ligation",
"pos": [
104,
112
]
} |
hl-a antigens on kidney cells and the use of kidney cells as a target in the detection of donor specific cytotoxic antibodies in renal transplantation . | target_anatomy_has_procedure | {
"id": "C0022646",
"name": "kidney",
"pos": [
17,
23
]
} | {
"id": "C0022671",
"name": "renal transplantation",
"pos": [
129,
150
]
} |
a one-stage abdominoperineal operation with end colostomy and bilateral ureteral implantation into the colon above the colostomy . | target_anatomy_has_procedure | {
"id": "C0009368",
"name": "colon",
"pos": [
103,
108
]
} | {
"id": "C0009410",
"name": "colostomy",
"pos": [
119,
128
]
} |
report of the anatomic results of early silicone oil removal in 23 eyes successfully treated by vitrectomy and silicone oil injection after membrane peeling . | target_anatomy_has_procedure | {
"id": "C0015392",
"name": "eyes",
"pos": [
67,
71
]
} | {
"id": "C0042903",
"name": "vitrectomy",
"pos": [
96,
106
]
} |
refraction , keratometry , and intraocular pressure were measured , 3 times a day , in 15 eyes 3-6 months after radial keratotomy , in 11 eyes one year after surgery , and in 5 controls . | target_anatomy_has_procedure | {
"id": "C0015392",
"name": "eyes",
"pos": [
90,
94
]
} | {
"id": "C0038901",
"name": "eyes",
"pos": [
138,
142
]
} |
the changes in volume of intraocular bubbles of air , sulphur hexafluoride , perfluoropropane and mixtures of these gases , were studied in human eyes , following vitrectomy for treatment of retinal detachment . | target_anatomy_has_procedure | {
"id": "C0015392",
"name": "eyes",
"pos": [
146,
150
]
} | {
"id": "C0042903",
"name": "vitrectomy",
"pos": [
163,
173
]
} |
time to peak contrast ( tpc ) and time constant of the washout exponential curve ( t ) were measured in 14 patients with stable effort angina pectoris and critical one vessel lesion before and after percutaneous transluminal coronary angioplasty ( ptca ) . | target_anatomy_has_procedure | {
"id": "C0005847",
"name": "vessel",
"pos": [
168,
174
]
} | {
"id": "C2936173",
"name": "percutaneous transluminal coronary angioplasty",
"pos": [
199,
245
]
} |
the author concludes that it is possible to achieve an acceptable 5-year survival in selected cases with metastasis to mediastinal lymph nodes : when the ct scan demonstrated mediastinal lymph nodes larger than 1.5 cm , mediastinoscopy was carried out and , if positive , the patient was judged inoperable . | target_anatomy_has_procedure | {
"id": "C0025066",
"name": "mediastinal",
"pos": [
119,
130
]
} | {
"id": "C0025065",
"name": "mediastinoscopy",
"pos": [
220,
235
]
} |
patients presenting with clinically negative necks who are initially treated with elective neck dissections show better survival rates than similar patients undergoing later salvage neck dissections . | target_anatomy_has_procedure | {
"id": "C0027530",
"name": "necks",
"pos": [
45,
50
]
} | {
"id": "C0398395",
"name": "neck dissections",
"pos": [
182,
198
]
} |
[ experimental research on the antibacterial property & toxic effect on the cochleovestibular structure of a new salt of neomycin : neomycin glucuronate ] . | therapeutic_class_of | {
"id": "C0279516",
"name": "antibacterial",
"pos": [
31,
44
]
} | {
"id": "C0027603",
"name": "neomycin",
"pos": [
132,
140
]
} |
[ preliminary observations on the antibacterial activity of kanamycin in vitro & on its action in human tuberculosis ] . | therapeutic_class_of | {
"id": "C0279516",
"name": "antibacterial",
"pos": [
34,
47
]
} | {
"id": "C0022487",
"name": "kanamycin",
"pos": [
60,
69
]
} |
the effect of perlapine , a sleep-promoting and sedative agent reported to lack antipsychotic efficacy , was compared in this system to haloperidol , chlorpromazine and clozapine . | therapeutic_class_of | {
"id": "C0040615",
"name": "antipsychotic",
"pos": [
80,
93
]
} | {
"id": "C0018546",
"name": "haloperidol",
"pos": [
136,
147
]
} |
antifungal synergism was established in vitro for the combination of amphotericin b and rifampin against the c. albicans isolate . | therapeutic_class_of | {
"id": "C0003308",
"name": "antifungal",
"pos": [
0,
10
]
} | {
"id": "C0002679",
"name": "amphotericin b",
"pos": [
69,
83
]
} |
in this study , chronic schizophrenic outpatients who had been maintained on various neuroleptics for an average of about 4 years had their previous medications ( approximately equivalent to 695 mg of chlorpromazine per day ) changed abruptly to either pimozide or fluphenazine given in single daily oral doses on a double-blind basis for a period of 52 weeks . | therapeutic_class_of | {
"id": "C0040615",
"name": "neuroleptics",
"pos": [
85,
97
]
} | {
"id": "C0031935",
"name": "pimozide",
"pos": [
253,
261
]
} |
to get information concerning the central background and the hierarchical structure of this behavior the neuroleptics haloperidol ( 0.14 mg/kg ) , clozapine ( 10 mg/kg ) and chlorpromazine ( 4 mg/kg ) were injected i.m . under controlled conditions . | therapeutic_class_of | {
"id": "C0040615",
"name": "neuroleptics",
"pos": [
105,
117
]
} | {
"id": "C0018546",
"name": "haloperidol",
"pos": [
118,
129
]
} |
the changes in 14c-dopamine accumulation formed from 14c-tyrosine in mice after treatment with three neuroleptics , cis ( z ) -flupenthixol , fluphenazine , and haloperidol , were followed for 6 days . | therapeutic_class_of | {
"id": "C0040615",
"name": "neuroleptics",
"pos": [
101,
113
]
} | {
"id": "C0018546",
"name": "haloperidol",
"pos": [
161,
172
]
} |
unlabelled : influence of anti-rheumatic drugs on human lymphocytes , especially t and b cell membranes , was studies with d-penicillamine , aurothiomalate , dexamethasone , cyclophosphamide , mitomycin c and aspirin . | therapeutic_class_of | {
"id": "C0003191",
"name": "anti-rheumatic drugs",
"pos": [
26,
46
]
} | {
"id": "C0030817",
"name": "penicillamine",
"pos": [
125,
138
]
} |
the antibacterial activity of rifampicin was studied in comparison with other antibiotics with respect to clinical strains isolated from cases with various purulent inflammatory processes caused by staphylococcus , e. coli , ps . aeruginose , proteus . | therapeutic_class_of | {
"id": "C0279516",
"name": "antibacterial",
"pos": [
4,
17
]
} | {
"id": "C0035608",
"name": "rifampicin",
"pos": [
30,
40
]
} |
2 reserpine and ro 4-1284 ( 2-hydroxy-2-ethyl-3-isobutyl-9,10-dimethoxy-hexahydro-11bh-benzo ( a ) quinolizine ) as well as neuroleptics ( e.g . chlorpromazine and haloperidol ) inhibited the na uptake , but the reserpine-like drugs were more potent . | therapeutic_class_of | {
"id": "C0040615",
"name": "neuroleptics",
"pos": [
124,
136
]
} | {
"id": "C0018546",
"name": "haloperidol",
"pos": [
164,
175
]
} |
[ the mode of action of antifungal agents . effect of horse erythrocyte membranes on amphotericin b ] . | therapeutic_class_of | {
"id": "C0003308",
"name": "antifungal agents",
"pos": [
24,
41
]
} | {
"id": "C0002679",
"name": "amphotericin b",
"pos": [
85,
99
]
} |
psychotropic drugs which are not alpha-receptor blockers , like butyrophenone neuroleptics ( pimozide and haloperidol ) or benzodiazepine tranquillizers , do not significantly diminsh the centrally induced hypotensive effect of clonidine . | therapeutic_class_of | {
"id": "C0040615",
"name": "neuroleptics",
"pos": [
78,
90
]
} | {
"id": "C0031935",
"name": "pimozide",
"pos": [
93,
101
]
} |
psychotropic drugs which are not alpha-receptor blockers , like butyrophenone neuroleptics ( pimozide and haloperidol ) or benzodiazepine tranquillizers , do not significantly diminsh the centrally induced hypotensive effect of clonidine . | therapeutic_class_of | {
"id": "C0040615",
"name": "neuroleptics",
"pos": [
78,
90
]
} | {
"id": "C0018546",
"name": "haloperidol",
"pos": [
106,
117
]
} |
the antibacterial properties of polyvinyl alcohol fibers added with morphocycline and neomycin are retained for 2 months in the body tissues . | therapeutic_class_of | {
"id": "C0279516",
"name": "antibacterial",
"pos": [
4,
17
]
} | {
"id": "C0027603",
"name": "neomycin",
"pos": [
86,
94
]
} |
in the isolated blood-perfused canine ventricular tissue , antiarrhythmic agents could be classified as having : 1 ) positive chronotropic and inotropic effects ( procainamide ) , 2 ) negative chronotropic but positive inotropic effects ( quinidine ) , and 3 ) negative chronotropic and inotropic effects ( lidocaine , ajmaline , diphenylhydantoin , and propranolol ) . | therapeutic_class_of | {
"id": "C0003195",
"name": "antiarrhythmic agents",
"pos": [
59,
80
]
} | {
"id": "C0033216",
"name": "procainamide",
"pos": [
163,
175
]
} |
in the isolated blood-perfused canine ventricular tissue , antiarrhythmic agents could be classified as having : 1 ) positive chronotropic and inotropic effects ( procainamide ) , 2 ) negative chronotropic but positive inotropic effects ( quinidine ) , and 3 ) negative chronotropic and inotropic effects ( lidocaine , ajmaline , diphenylhydantoin , and propranolol ) . | therapeutic_class_of | {
"id": "C0003195",
"name": "antiarrhythmic agents",
"pos": [
59,
80
]
} | {
"id": "C0034414",
"name": "quinidine",
"pos": [
239,
248
]
} |
in the isolated blood-perfused canine ventricular tissue , antiarrhythmic agents could be classified as having : 1 ) positive chronotropic and inotropic effects ( procainamide ) , 2 ) negative chronotropic but positive inotropic effects ( quinidine ) , and 3 ) negative chronotropic and inotropic effects ( lidocaine , ajmaline , diphenylhydantoin , and propranolol ) . | therapeutic_class_of | {
"id": "C0003195",
"name": "antiarrhythmic agents",
"pos": [
59,
80
]
} | {
"id": "C0023660",
"name": "lidocaine",
"pos": [
307,
316
]
} |
the action of quinidine on heart microsomal and mitochondrial calcium binding in the presence of mgatp was studied under different experimental conditions and compared with other antiarrhythmic agents such as procaine amide and lidocaine . | therapeutic_class_of | {
"id": "C0003195",
"name": "antiarrhythmic agents",
"pos": [
179,
200
]
} | {
"id": "C0033216",
"name": "procaine amide",
"pos": [
209,
223
]
} |
the action of quinidine on heart microsomal and mitochondrial calcium binding in the presence of mgatp was studied under different experimental conditions and compared with other antiarrhythmic agents such as procaine amide and lidocaine . | therapeutic_class_of | {
"id": "C0003195",
"name": "antiarrhythmic agents",
"pos": [
179,
200
]
} | {
"id": "C0023660",
"name": "lidocaine",
"pos": [
228,
237
]
} |
the antiepileptic drug sodium valproate ( vpa ) can provoke a thrombocytopenia or platelet dysfunction , with or without hemorrhages . | therapeutic_class_of | {
"id": "C0003299",
"name": "antiepileptic drug",
"pos": [
4,
22
]
} | {
"id": "C0037567",
"name": "sodium valproate",
"pos": [
23,
39
]
} |
the antidepressant effect of maprotiline , a tetracyclic compound , was compared with that of imipramine in a four-week , double-blind , placebo controlled study with neurotic depressives . | therapeutic_class_of | {
"id": "C0003289",
"name": "antidepressant",
"pos": [
4,
18
]
} | {
"id": "C0020934",
"name": "imipramine",
"pos": [
94,
104
]
} |
neuroleptic drugs , such as haloperidol , cause an allosteric activation of striatal th which can be measured in vitro as a decrease in the km of th for cofactor ( 2-amino-4-hydroxy-6,7-dimethyl-5,6,7,8-tetrahydropterine ) . | therapeutic_class_of | {
"id": "C0040615",
"name": "neuroleptic drugs",
"pos": [
0,
17
]
} | {
"id": "C0018546",
"name": "haloperidol",
"pos": [
28,
39
]
} |
all produced distinct antiarrhythmic effects at doses considerably lower than doses of lidocaine or tocainide producing comparable effects . | therapeutic_class_of | {
"id": "C0003195",
"name": "antiarrhythmic",
"pos": [
22,
36
]
} | {
"id": "C0023660",
"name": "lidocaine",
"pos": [
87,
96
]
} |
cefotaxime diffuses in the c.s.f . and gives concentrations which ensures an antibacterial activity that ampicillin could not reach : in particular against haemophilus influenzae and enterobacteriaceae . | therapeutic_class_of | {
"id": "C0279516",
"name": "antibacterial",
"pos": [
77,
90
]
} | {
"id": "C0002680",
"name": "ampicillin",
"pos": [
105,
115
]
} |
neither stereotyped motor actions nor repetitive choice of position contributed to this effect which could be blocked by pre-treatment with the neuroleptic haloperidol . | therapeutic_class_of | {
"id": "C0040615",
"name": "neuroleptic",
"pos": [
144,
155
]
} | {
"id": "C0018546",
"name": "haloperidol",
"pos": [
156,
167
]
} |
[ quantitative evaluation of an antiarrhythmic therapy ( disopyramide ) in patients with frequent premature ventricular contractions ( pvc ) using a computer-assisted long-term ecg analysis system ( author 's transl ) ] . | therapeutic_class_of | {
"id": "C0003195",
"name": "antiarrhythmic",
"pos": [
32,
46
]
} | {
"id": "C0012702",
"name": "disopyramide",
"pos": [
57,
69
]
} |
[ tetrodotoxin potentiation of the antiarrhythmic action of lidocaine in the late stage of experimental myocardial infarct ] . | therapeutic_class_of | {
"id": "C0003195",
"name": "antiarrhythmic",
"pos": [
35,
49
]
} | {
"id": "C0023660",
"name": "lidocaine",
"pos": [
60,
69
]
} |
this finding suggests that the antiarrhythmic action of lidocaine in the late stage of myocardial infarction is due to inhibition of the fast inward , sodium current . | therapeutic_class_of | {
"id": "C0003195",
"name": "antiarrhythmic",
"pos": [
31,
45
]
} | {
"id": "C0023660",
"name": "lidocaine",
"pos": [
56,
65
]
} |
this model suggests that the desensitization of postsynaptic beta-receptors by antidepressants should be accelerated by the inhibition of the presynaptic alpha 2- adrenergic system , and we have indeed observed such an effect in preliminary studies with desipramine and phenoxybenzamine ( pbz ) combined . | therapeutic_class_of | {
"id": "C0003289",
"name": "antidepressants",
"pos": [
79,
94
]
} | {
"id": "C0011685",
"name": "desipramine",
"pos": [
254,
265
]
} |
present treatment is based on the routine use of antifungal agents : e.g . amphotericin b , 5-fluorocytosine , imidazole derivatives ( ketoconazole ) according to the sensitivity of the fungi . | therapeutic_class_of | {
"id": "C0003308",
"name": "antifungal agents",
"pos": [
49,
66
]
} | {
"id": "C0002679",
"name": "amphotericin b",
"pos": [
75,
89
]
} |
present treatment is based on the routine use of antifungal agents : e.g . amphotericin b , 5-fluorocytosine , imidazole derivatives ( ketoconazole ) according to the sensitivity of the fungi . | therapeutic_class_of | {
"id": "C0003308",
"name": "antifungal agents",
"pos": [
49,
66
]
} | {
"id": "C0016278",
"name": "5-fluorocytosine",
"pos": [
92,
108
]
} |
present treatment is based on the routine use of antifungal agents : e.g . amphotericin b , 5-fluorocytosine , imidazole derivatives ( ketoconazole ) according to the sensitivity of the fungi . | therapeutic_class_of | {
"id": "C0003308",
"name": "antifungal agents",
"pos": [
49,
66
]
} | {
"id": "C0022625",
"name": "ketoconazole",
"pos": [
135,
147
]
} |
however , there are conflicting reports concerning the existence of a `` '' therapeutic window '' '' for the usual antidepressives such as amitriptyline , nortriptyline , chlorimipramine , imipramine , desipramine and maprotiline . | therapeutic_class_of | {
"id": "C0003289",
"name": "l antidepressiv",
"pos": [
113,
128
]
} | {
"id": "C0002600",
"name": "amitriptyli",
"pos": [
139,
150
]
} |
however , there are conflicting reports concerning the existence of a `` '' therapeutic window '' '' for the usual antidepressives such as amitriptyline , nortriptyline , chlorimipramine , imipramine , desipramine and maprotiline . | therapeutic_class_of | {
"id": "C0003289",
"name": "l antidepressiv",
"pos": [
113,
128
]
} | {
"id": "C0028420",
"name": ", nortriptyli",
"pos": [
153,
166
]
} |
however , there are conflicting reports concerning the existence of a `` '' therapeutic window '' '' for the usual antidepressives such as amitriptyline , nortriptyline , chlorimipramine , imipramine , desipramine and maprotiline . | therapeutic_class_of | {
"id": "C0003289",
"name": "l antidepressiv",
"pos": [
113,
128
]
} | {
"id": "C0009010",
"name": ", chlorimiprami",
"pos": [
169,
184
]
} |
however , there are conflicting reports concerning the existence of a `` '' therapeutic window '' '' for the usual antidepressives such as amitriptyline , nortriptyline , chlorimipramine , imipramine , desipramine and maprotiline . | therapeutic_class_of | {
"id": "C0003289",
"name": "l antidepressiv",
"pos": [
113,
128
]
} | {
"id": "C0020934",
"name": ", imiprami",
"pos": [
187,
197
]
} |
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