id
stringlengths 15
19
| document_id
stringlengths 15
19
| passages
list | entities
list | events
list | coreferences
list | relations
list |
|---|---|---|---|---|---|---|
split_0_train_29600
|
split_0_train_29600
|
[
{
"id": "split_0_train_29600_passage",
"type": "progene_text",
"text": [
"Short - term memory resists the depressant effect of the nonimmobilizer 1-2-dichlorohexafluorocyclobutane ( 2N ) more than long - term memory ."
],
"offsets": [
[
0,
143
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29601
|
split_0_train_29601
|
[
{
"id": "split_0_train_29601_passage",
"type": "progene_text",
"text": [
"The nonimmobilizer 1,2-dichlorohexafluorocyclobutane ( 2N , also termed F6 ) does not suppress movement to noxious stimuli but does suppress learning of fear - potentiated startle ."
],
"offsets": [
[
0,
181
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29602
|
split_0_train_29602
|
[
{
"id": "split_0_train_29602_passage",
"type": "progene_text",
"text": [
"The mechanism whereby 2N suppresses this learning is unknown ."
],
"offsets": [
[
0,
62
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29603
|
split_0_train_29603
|
[
{
"id": "split_0_train_29603_passage",
"type": "progene_text",
"text": [
"Herein , we report the effect of 2N on suppression of two other forms of learning , fear conditioning to context and to tone ."
],
"offsets": [
[
0,
126
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29604
|
split_0_train_29604
|
[
{
"id": "split_0_train_29604_passage",
"type": "progene_text",
"text": [
"Because 2N does not cause sedation , we could study the effect of 2N on short - term memory ( memory for fear conditioning measured during or immediately after training ) as well as on long - term memory ( measured 24 h after training ) ."
],
"offsets": [
[
0,
238
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29605
|
split_0_train_29605
|
[
{
"id": "split_0_train_29605_passage",
"type": "progene_text",
"text": [
"The EC(50) for suppression of long - term memory ( the concentration decreasing memory by 50 % ) of fear conditioning to context was 2.00 % plus / minus 0.01 % ( mean plus / minus SEM ) , and for fear conditioning to tone was 3.45 % plus / minus 0.26 % , ( P < 0.05 ) ."
],
"offsets": [
[
0,
269
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29606
|
split_0_train_29606
|
[
{
"id": "split_0_train_29606_passage",
"type": "progene_text",
"text": [
"The EC(50) for suppression of short - term memory of fear conditioning to context was 2.59 % plus / minus 0.21 % ( P < 0.05 , compared with long - term memory of context conditioning ) , whereas short - term memory of fear conditioning to tone was not suppressed by 3.5 % , the largest concentration studied ."
],
"offsets": [
[
0,
309
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29607
|
split_0_train_29607
|
[
{
"id": "split_0_train_29607_passage",
"type": "progene_text",
"text": [
"Thus , short - term memory resists the depressant effect of 2N more than long - term memory , fear conditioning to tone is less vulnerable to the effect of 2N than fear conditioning to context , and 3.5 % 2N does not preclude transmission of tone and shock signals to the site where tone - shock associations are formed ."
],
"offsets": [
[
0,
321
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29608
|
split_0_train_29608
|
[
{
"id": "split_0_train_29608_passage",
"type": "progene_text",
"text": [
"IMPLICATIONS :"
],
"offsets": [
[
0,
14
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29609
|
split_0_train_29609
|
[
{
"id": "split_0_train_29609_passage",
"type": "progene_text",
"text": [
"The nonimmobilizer 1,2-dichlorohexafluorocyclobutane has a greater depressant effect on long - term memory than short - term memory , suggesting that it impairs the processes responsible for the retention of memory more than for the formation of memory itself ."
],
"offsets": [
[
0,
261
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29610
|
split_0_train_29610
|
[
{
"id": "split_0_train_29610_passage",
"type": "progene_text",
"text": [
"[ The effect of heparin on the deep second - degree burn in scalded rats ]"
],
"offsets": [
[
0,
74
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29611
|
split_0_train_29611
|
[
{
"id": "split_0_train_29611_passage",
"type": "progene_text",
"text": [
"OBJECTIVE :"
],
"offsets": [
[
0,
11
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29612
|
split_0_train_29612
|
[
{
"id": "split_0_train_29612_passage",
"type": "progene_text",
"text": [
"To investigate the effects of heparin on deep second - degree burn in scalded rats ."
],
"offsets": [
[
0,
84
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29613
|
split_0_train_29613
|
[
{
"id": "split_0_train_29613_passage",
"type": "progene_text",
"text": [
"METHODS :"
],
"offsets": [
[
0,
9
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29614
|
split_0_train_29614
|
[
{
"id": "split_0_train_29614_passage",
"type": "progene_text",
"text": [
"Thirty Sprague - Dawley rats inflicted with 20 % TBSA deep second - degree scalding on the back were employed as the model and were randomly divided into two groups ."
],
"offsets": [
[
0,
166
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29615
|
split_0_train_29615
|
[
{
"id": "split_0_train_29615_passage",
"type": "progene_text",
"text": [
"i,e heparin ( H ) and normal saline groups ( N ) ."
],
"offsets": [
[
0,
50
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29616
|
split_0_train_29616
|
[
{
"id": "split_0_train_29616_passage",
"type": "progene_text",
"text": [
"Heparin ( 100 U . kg(-1) . day(-1) ) was injected subcutaneously to the rats in H group while normal saline to those in N group once a day ."
],
"offsets": [
[
0,
140
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29617
|
split_0_train_29617
|
[
{
"id": "split_0_train_29617_passage",
"type": "progene_text",
"text": [
"Wound healing rate and immunological indices were determined simultaneously ."
],
"offsets": [
[
0,
77
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29618
|
split_0_train_29618
|
[
{
"id": "split_0_train_29618_passage",
"type": "progene_text",
"text": [
"RESULTS :"
],
"offsets": [
[
0,
9
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29619
|
split_0_train_29619
|
[
{
"id": "split_0_train_29619_passage",
"type": "progene_text",
"text": [
"(1 )"
],
"offsets": [
[
0,
4
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29620
|
split_0_train_29620
|
[
{
"id": "split_0_train_29620_passage",
"type": "progene_text",
"text": [
"The wound healing time was much shorter in H group than that in N group ( P < 0.005 ) ."
],
"offsets": [
[
0,
87
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29621
|
split_0_train_29621
|
[
{
"id": "split_0_train_29621_passage",
"type": "progene_text",
"text": [
"The granulation tissue growth condition examined by LM and EM was much better in H group that than in N group ."
],
"offsets": [
[
0,
111
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29622
|
split_0_train_29622
|
[
{
"id": "split_0_train_29622_passage",
"type": "progene_text",
"text": [
"(2 )"
],
"offsets": [
[
0,
4
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29623
|
split_0_train_29623
|
[
{
"id": "split_0_train_29623_passage",
"type": "progene_text",
"text": [
"The lymphocytic transforming ratio in H group was evidently increased ( P < 0.005 ) ."
],
"offsets": [
[
0,
85
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29624
|
split_0_train_29624
|
[
{
"id": "split_0_train_29624_passage",
"type": "progene_text",
"text": [
"And the phagocytic function of the macrophages increased significantly ( P < 0.05 ) ."
],
"offsets": [
[
0,
85
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29625
|
split_0_train_29625
|
[
{
"id": "split_0_train_29625_passage",
"type": "progene_text",
"text": [
"But there was no difference between the two groups in terms of hemoltytic plaque test ( P > 0.05 ) ."
],
"offsets": [
[
0,
100
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29626
|
split_0_train_29626
|
[
{
"id": "split_0_train_29626_passage",
"type": "progene_text",
"text": [
"CONCLUSION :"
],
"offsets": [
[
0,
12
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29627
|
split_0_train_29627
|
[
{
"id": "split_0_train_29627_passage",
"type": "progene_text",
"text": [
"Injection of heparin subcutaneously could accelerate burn wound healing and strengthen the systemic cellular immune potential and the macrophage phagocytic capacity of the host , but exerted no effect on the humoral immunity ."
],
"offsets": [
[
0,
226
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29628
|
split_0_train_29628
|
[
{
"id": "split_0_train_29628_passage",
"type": "progene_text",
"text": [
"A novel negative regulatory element in the human collagenase-3 proximal promoter region ."
],
"offsets": [
[
0,
89
]
]
}
] |
[
{
"id": "split_0_train_47748_entity",
"type": "progene_text",
"text": [
"collagenase-3"
],
"offsets": [
[
49,
62
]
],
"normalized": []
}
] |
[] |
[] |
[] |
split_0_train_29629
|
split_0_train_29629
|
[
{
"id": "split_0_train_29629_passage",
"type": "progene_text",
"text": [
"We have identified in the human collagenase-3 promoter a novel negative regulatory element , GAAAAGAAAAAG , designated AGRE ( AG - Rich Element ) ."
],
"offsets": [
[
0,
147
]
]
}
] |
[
{
"id": "split_0_train_47749_entity",
"type": "progene_text",
"text": [
"collagenase-3"
],
"offsets": [
[
32,
45
]
],
"normalized": []
}
] |
[] |
[] |
[] |
split_0_train_29630
|
split_0_train_29630
|
[
{
"id": "split_0_train_29630_passage",
"type": "progene_text",
"text": [
"The AGRE site functionality was characterized in human osteoarthritic ( OA ) chondrocytes as well as four cell lines ."
],
"offsets": [
[
0,
118
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29631
|
split_0_train_29631
|
[
{
"id": "split_0_train_29631_passage",
"type": "progene_text",
"text": [
"The cells were transfected with a plasmid consisting of the first 133 bp of the collagenase-3 promoter and its AGRE mutated or deleted derivatives ."
],
"offsets": [
[
0,
148
]
]
}
] |
[
{
"id": "split_0_train_47750_entity",
"type": "progene_text",
"text": [
"collagenase-3"
],
"offsets": [
[
80,
93
]
],
"normalized": []
}
] |
[] |
[] |
[] |
split_0_train_29632
|
split_0_train_29632
|
[
{
"id": "split_0_train_29632_passage",
"type": "progene_text",
"text": [
"The absence of a functional AGRE site resulted in a statistically significant increase of the collagenase-3 basal transcription that was not affected by the collagenase-3 inducers IL-1beta and TGF-beta1 ."
],
"offsets": [
[
0,
204
]
]
}
] |
[
{
"id": "split_0_train_47751_entity",
"type": "progene_text",
"text": [
"AGRE"
],
"offsets": [
[
28,
32
]
],
"normalized": []
},
{
"id": "split_0_train_47752_entity",
"type": "progene_text",
"text": [
"collagenase-3"
],
"offsets": [
[
94,
107
]
],
"normalized": []
},
{
"id": "split_0_train_47753_entity",
"type": "progene_text",
"text": [
"collagenase-3"
],
"offsets": [
[
157,
170
]
],
"normalized": []
},
{
"id": "split_0_train_47754_entity",
"type": "progene_text",
"text": [
"IL-1beta"
],
"offsets": [
[
180,
188
]
],
"normalized": []
},
{
"id": "split_0_train_47755_entity",
"type": "progene_text",
"text": [
"TGF-beta1"
],
"offsets": [
[
193,
202
]
],
"normalized": []
}
] |
[] |
[] |
[] |
split_0_train_29633
|
split_0_train_29633
|
[
{
"id": "split_0_train_29633_passage",
"type": "progene_text",
"text": [
"Two specific protein - AGRE binding complexes were detected by EMSA , and their presence depended on the physiological state of the cell ."
],
"offsets": [
[
0,
138
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29634
|
split_0_train_29634
|
[
{
"id": "split_0_train_29634_passage",
"type": "progene_text",
"text": [
"Indeed , normal chondrocytes and synovial fibroblasts and the four cell lines showed only a slower - migrating complex ( complex 1 ) ."
],
"offsets": [
[
0,
134
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29635
|
split_0_train_29635
|
[
{
"id": "split_0_train_29635_passage",
"type": "progene_text",
"text": [
"In OA chondrocytes , the type of complex discriminated two groups--the low - OA chondrocytes , showing low collagenase - 3 basal levels and high inducibility of IL-1beta stimulation ( complex 1 ) , and the high - OA chondrocytes with high collagenase - 3 basal levels and low IL-1beta inducibility ( a faster - migrating complex , designated complex 2 ) ."
],
"offsets": [
[
0,
355
]
]
}
] |
[
{
"id": "split_0_train_47756_entity",
"type": "progene_text",
"text": [
"collagenase - 3"
],
"offsets": [
[
107,
122
]
],
"normalized": []
},
{
"id": "split_0_train_47757_entity",
"type": "progene_text",
"text": [
"IL-1beta"
],
"offsets": [
[
161,
169
]
],
"normalized": []
},
{
"id": "split_0_train_47758_entity",
"type": "progene_text",
"text": [
"collagenase - 3"
],
"offsets": [
[
239,
254
]
],
"normalized": []
},
{
"id": "split_0_train_47759_entity",
"type": "progene_text",
"text": [
"IL-1beta"
],
"offsets": [
[
276,
284
]
],
"normalized": []
}
] |
[] |
[] |
[] |
split_0_train_29636
|
split_0_train_29636
|
[
{
"id": "split_0_train_29636_passage",
"type": "progene_text",
"text": [
"UV cross - linking revealed the presence of 48 and 97 kDa proteins in complex 1 and 27 , 35 , and 73 kDa proteins in complex 2 ."
],
"offsets": [
[
0,
128
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29637
|
split_0_train_29637
|
[
{
"id": "split_0_train_29637_passage",
"type": "progene_text",
"text": [
"These findings suggest that the AGRE site plays a rate - limiting role in human collagenase-3 production ."
],
"offsets": [
[
0,
106
]
]
}
] |
[
{
"id": "split_0_train_47760_entity",
"type": "progene_text",
"text": [
"collagenase-3"
],
"offsets": [
[
80,
93
]
],
"normalized": []
}
] |
[] |
[] |
[] |
split_0_train_29638
|
split_0_train_29638
|
[
{
"id": "split_0_train_29638_passage",
"type": "progene_text",
"text": [
"Serum TA90 immune complex assay can predict outcome after resection of thick ( > or = 4 mm ) primary melanoma and sentinel lymphadenectomy ."
],
"offsets": [
[
0,
140
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29639
|
split_0_train_29639
|
[
{
"id": "split_0_train_29639_passage",
"type": "progene_text",
"text": [
"BACKGROUND :"
],
"offsets": [
[
0,
12
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29640
|
split_0_train_29640
|
[
{
"id": "split_0_train_29640_passage",
"type": "progene_text",
"text": [
"We hypothesized that the postoperative serum level of TA90-IC , an immune complex of a 90 - kDa tumor - associated antigen and its antibody , might have a significant correlation with recurrence and survival in patients with thick primary melanomas ."
],
"offsets": [
[
0,
250
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29641
|
split_0_train_29641
|
[
{
"id": "split_0_train_29641_passage",
"type": "progene_text",
"text": [
"METHODS :"
],
"offsets": [
[
0,
9
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29642
|
split_0_train_29642
|
[
{
"id": "split_0_train_29642_passage",
"type": "progene_text",
"text": [
"We used our prospective melanoma database to identify all patients who underwent wide local excision and sentinel lymphadenectomy for primary melanomas > or = 4 mm and from whom sera had been collected and cryopreserved within 6 months after surgery ."
],
"offsets": [
[
0,
251
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29643
|
split_0_train_29643
|
[
{
"id": "split_0_train_29643_passage",
"type": "progene_text",
"text": [
"These sera were analyzed in a blinded fashion for TA90-IC status by using our double - determinant enzyme - linked immunosorbent assay ."
],
"offsets": [
[
0,
136
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29644
|
split_0_train_29644
|
[
{
"id": "split_0_train_29644_passage",
"type": "progene_text",
"text": [
"Results were correlated with disease - free survival ( DFS ) and overall survival ( OS ) ."
],
"offsets": [
[
0,
90
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29645
|
split_0_train_29645
|
[
{
"id": "split_0_train_29645_passage",
"type": "progene_text",
"text": [
"Standard prognostic factors for melanoma were then compared with TA90-IC status for the prediction of DFS and OS ."
],
"offsets": [
[
0,
114
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29646
|
split_0_train_29646
|
[
{
"id": "split_0_train_29646_passage",
"type": "progene_text",
"text": [
"RESULTS :"
],
"offsets": [
[
0,
9
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29647
|
split_0_train_29647
|
[
{
"id": "split_0_train_29647_passage",
"type": "progene_text",
"text": [
"The sensitivity and specificity of the TA90 - IC assay for predicting recurrence were 70 % and 85 % , respectively ."
],
"offsets": [
[
0,
116
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29648
|
split_0_train_29648
|
[
{
"id": "split_0_train_29648_passage",
"type": "progene_text",
"text": [
"Five - year DFS and OS rates were higher for the TA90 - IC - negative group than the positive group ."
],
"offsets": [
[
0,
101
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29649
|
split_0_train_29649
|
[
{
"id": "split_0_train_29649_passage",
"type": "progene_text",
"text": [
"The differences in DFS and OS between the TA90 - IC - negative and - positive groups were significant ."
],
"offsets": [
[
0,
103
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29650
|
split_0_train_29650
|
[
{
"id": "split_0_train_29650_passage",
"type": "progene_text",
"text": [
"At a median follow - up of 25 months , multivariate analysis identified postoperative TA90-IC status and sex as significant predictors of DFS ."
],
"offsets": [
[
0,
143
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29651
|
split_0_train_29651
|
[
{
"id": "split_0_train_29651_passage",
"type": "progene_text",
"text": [
"TA90 - IC status was the only independent prognostic factor with multivariate analysis ."
],
"offsets": [
[
0,
88
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29652
|
split_0_train_29652
|
[
{
"id": "split_0_train_29652_passage",
"type": "progene_text",
"text": [
"CONCLUSIONS :"
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"offsets": [
[
0,
13
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29653
|
split_0_train_29653
|
[
{
"id": "split_0_train_29653_passage",
"type": "progene_text",
"text": [
"TA90 - IC status after resection of thick primary melanoma accurately predicts outcome ."
],
"offsets": [
[
0,
88
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]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29654
|
split_0_train_29654
|
[
{
"id": "split_0_train_29654_passage",
"type": "progene_text",
"text": [
"A positive postoperative TA90 - IC level might affect a decision regarding adjuvant therapy , regardless of regional nodal status ."
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"offsets": [
[
0,
131
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29655
|
split_0_train_29655
|
[
{
"id": "split_0_train_29655_passage",
"type": "progene_text",
"text": [
"FOXP2 is not a major susceptibility gene for autism or specific language impairment ."
],
"offsets": [
[
0,
85
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]
}
] |
[
{
"id": "split_0_train_47761_entity",
"type": "progene_text",
"text": [
"FOXP2"
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"offsets": [
[
0,
5
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],
"normalized": []
}
] |
[] |
[] |
[] |
split_0_train_29656
|
split_0_train_29656
|
[
{
"id": "split_0_train_29656_passage",
"type": "progene_text",
"text": [
"The FOXP2 gene , located on human 7q31 ( at the SPCH1 locus ) , encodes a transcription factor containing a polyglutamine tract and a forkhead domain ."
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[
0,
151
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]
}
] |
[
{
"id": "split_0_train_47762_entity",
"type": "progene_text",
"text": [
"FOXP2"
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4,
9
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{
"id": "split_0_train_47763_entity",
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"text": [
"SPCH1"
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[
48,
53
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{
"id": "split_0_train_47764_entity",
"type": "progene_text",
"text": [
"transcription factor"
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"offsets": [
[
74,
94
]
],
"normalized": []
}
] |
[] |
[] |
[] |
split_0_train_29657
|
split_0_train_29657
|
[
{
"id": "split_0_train_29657_passage",
"type": "progene_text",
"text": [
"FOXP2 is mutated in a severe monogenic form of speech and language impairment , segregating within a single large pedigree , and is also disrupted by a translocation in an isolated case ."
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[
0,
187
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]
}
] |
[
{
"id": "split_0_train_47765_entity",
"type": "progene_text",
"text": [
"FOXP2"
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"offsets": [
[
0,
5
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],
"normalized": []
}
] |
[] |
[] |
[] |
split_0_train_29658
|
split_0_train_29658
|
[
{
"id": "split_0_train_29658_passage",
"type": "progene_text",
"text": [
"Several studies of autistic disorder have demonstrated linkage to a similar region of 7q ( the AUTS1 locus ) , leading to the proposal that a single genetic factor on 7q31 contributes to both autism and language disorders ."
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"offsets": [
[
0,
223
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]
}
] |
[
{
"id": "split_0_train_47766_entity",
"type": "progene_text",
"text": [
"AUTS1"
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"offsets": [
[
95,
100
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"normalized": []
}
] |
[] |
[] |
[] |
split_0_train_29659
|
split_0_train_29659
|
[
{
"id": "split_0_train_29659_passage",
"type": "progene_text",
"text": [
"In the present study , we directly evaluate the impact of the FOXP2 gene with regard to both complex language impairments and autism , through use of association and mutation screening analyses ."
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[
0,
195
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]
}
] |
[
{
"id": "split_0_train_47767_entity",
"type": "progene_text",
"text": [
"FOXP2"
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[
62,
67
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}
] |
[] |
[] |
[] |
split_0_train_29660
|
split_0_train_29660
|
[
{
"id": "split_0_train_29660_passage",
"type": "progene_text",
"text": [
"We conclude that coding - region variants in FOXP2 do not underlie the AUTS1 linkage and that the gene is unlikely to play a role in autism or more common forms of language impairment ."
],
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[
0,
185
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]
}
] |
[
{
"id": "split_0_train_47768_entity",
"type": "progene_text",
"text": [
"FOXP2"
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45,
50
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{
"id": "split_0_train_47769_entity",
"type": "progene_text",
"text": [
"AUTS1"
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"offsets": [
[
71,
76
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],
"normalized": []
}
] |
[] |
[] |
[] |
split_0_train_29661
|
split_0_train_29661
|
[
{
"id": "split_0_train_29661_passage",
"type": "progene_text",
"text": [
"Eyelid lymphatics II : a search for drainage patterns in the monkey and correlations with human lymphatics ."
],
"offsets": [
[
0,
108
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29662
|
split_0_train_29662
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[
{
"id": "split_0_train_29662_passage",
"type": "progene_text",
"text": [
"PURPOSE :"
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"offsets": [
[
0,
9
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]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29663
|
split_0_train_29663
|
[
{
"id": "split_0_train_29663_passage",
"type": "progene_text",
"text": [
"To study the lymphatic drainage of the cynomolgus monkey through the use of lymphoscintigraphy ."
],
"offsets": [
[
0,
96
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]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29664
|
split_0_train_29664
|
[
{
"id": "split_0_train_29664_passage",
"type": "progene_text",
"text": [
"METHODS :"
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"offsets": [
[
0,
9
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]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29665
|
split_0_train_29665
|
[
{
"id": "split_0_train_29665_passage",
"type": "progene_text",
"text": [
"Lymphoscintigraphy with 500 microCi of 99mTechnetium sulfur colloid injected at specific sites around the eyelids was performed with five cynomolgus monkeys in lateral and ventral positions ."
],
"offsets": [
[
0,
191
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29666
|
split_0_train_29666
|
[
{
"id": "split_0_train_29666_passage",
"type": "progene_text",
"text": [
"RESULTS :"
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"offsets": [
[
0,
9
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]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29667
|
split_0_train_29667
|
[
{
"id": "split_0_train_29667_passage",
"type": "progene_text",
"text": [
"Lymphoscintigraphy of the monkey eyelid and periocular tissue revealed lymphatic drainage to the parotid lymph nodes from the entire upper eyelid , medial canthus , and lateral lower eyelid and drainage to the submandibular lymph nodes from the medial and central lower eyelid ."
],
"offsets": [
[
0,
278
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29668
|
split_0_train_29668
|
[
{
"id": "split_0_train_29668_passage",
"type": "progene_text",
"text": [
"In addition to draining to the parotid lymph nodes , the central upper eyelid was also seen to drain to the submandibular lymph nodes ."
],
"offsets": [
[
0,
135
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29669
|
split_0_train_29669
|
[
{
"id": "split_0_train_29669_passage",
"type": "progene_text",
"text": [
"CONCLUSIONS :"
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"offsets": [
[
0,
13
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]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29670
|
split_0_train_29670
|
[
{
"id": "split_0_train_29670_passage",
"type": "progene_text",
"text": [
"Lymphoscintigraphy of the cynomolgus monkey eyelids reveals discrete lymphatic drainage pathways for the upper and lower eyelids and a dual pathway for the central upper eyelid ."
],
"offsets": [
[
0,
178
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]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29671
|
split_0_train_29671
|
[
{
"id": "split_0_train_29671_passage",
"type": "progene_text",
"text": [
"Future studies will help to clarify the lymphatic drainage pathways of human eyelids ."
],
"offsets": [
[
0,
86
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]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29672
|
split_0_train_29672
|
[
{
"id": "split_0_train_29672_passage",
"type": "progene_text",
"text": [
"A hydro - chemical study of a mountainous watershed : the Ganga , India ."
],
"offsets": [
[
0,
73
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]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29673
|
split_0_train_29673
|
[
{
"id": "split_0_train_29673_passage",
"type": "progene_text",
"text": [
"A hydro - chemical study has been carried out on a 37 - km stretch of the River Ganga from Deoprayag to Rishikesh ( India ) during the period from April 1999 to March 2000 ."
],
"offsets": [
[
0,
173
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]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29674
|
split_0_train_29674
|
[
{
"id": "split_0_train_29674_passage",
"type": "progene_text",
"text": [
"The assessment of sediment and nutrient load has been considered to evaluate the current state of pollution through real time measurements ."
],
"offsets": [
[
0,
140
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]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29675
|
split_0_train_29675
|
[
{
"id": "split_0_train_29675_passage",
"type": "progene_text",
"text": [
"The values of pH and conductance are well within the limits prescribed for drinking water ."
],
"offsets": [
[
0,
91
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]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29676
|
split_0_train_29676
|
[
{
"id": "split_0_train_29676_passage",
"type": "progene_text",
"text": [
"The maximum suspended sediment concentrations of 1 , 405 and 2 , 002 mg / L were recorded at Deoprayag and Rishikesh , respectively , during the rainy season ."
],
"offsets": [
[
0,
159
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29677
|
split_0_train_29677
|
[
{
"id": "split_0_train_29677_passage",
"type": "progene_text",
"text": [
"A large amount of sediment and nutrient load is transported from the watershed during the rainy season ."
],
"offsets": [
[
0,
104
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]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29678
|
split_0_train_29678
|
[
{
"id": "split_0_train_29678_passage",
"type": "progene_text",
"text": [
"Concentrations of N(O3-)-N and N(H3-)-N at Deoprayag varied from 0.30 to 0.50 and 0.02 to 0.12 mg / L , respectively , depending on season ."
],
"offsets": [
[
0,
140
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29679
|
split_0_train_29679
|
[
{
"id": "split_0_train_29679_passage",
"type": "progene_text",
"text": [
"Examination of the results showed clearly that N(H3-)-N was generally low as compared to N03-N ."
],
"offsets": [
[
0,
96
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]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29680
|
split_0_train_29680
|
[
{
"id": "split_0_train_29680_passage",
"type": "progene_text",
"text": [
"Depending on the pH and temperature of soils , NH4 + and NO3 - ions are produced in the watershed through ammonification and nitrification of organic matter and mobilized into rivers through run - off ."
],
"offsets": [
[
0,
202
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]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29681
|
split_0_train_29681
|
[
{
"id": "split_0_train_29681_passage",
"type": "progene_text",
"text": [
"Dissolved N and P from fertilizer application , sewage and non - point source run - off contribute significant quantities of these nutrients in river water ."
],
"offsets": [
[
0,
157
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29682
|
split_0_train_29682
|
[
{
"id": "split_0_train_29682_passage",
"type": "progene_text",
"text": [
"The nitrate and phosphate are transported from the cropland either by being adsorbed on to soil particles that are subsequently eroded , or dissolved in runoff water from agricultural land ."
],
"offsets": [
[
0,
190
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29683
|
split_0_train_29683
|
[
{
"id": "split_0_train_29683_passage",
"type": "progene_text",
"text": [
"The data generated through the study will be useful for development and management planning of the hilly watershed ."
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"offsets": [
[
0,
116
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]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29684
|
split_0_train_29684
|
[
{
"id": "split_0_train_29684_passage",
"type": "progene_text",
"text": [
"Stanniocalcin from an ancient teleost : a monomeric form of the hormone and a possible extracorpuscular distribution ."
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"offsets": [
[
0,
118
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]
}
] |
[
{
"id": "split_0_train_47770_entity",
"type": "progene_text",
"text": [
"Stanniocalcin"
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"offsets": [
[
0,
13
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"normalized": []
}
] |
[] |
[] |
[] |
split_0_train_29685
|
split_0_train_29685
|
[
{
"id": "split_0_train_29685_passage",
"type": "progene_text",
"text": [
"Stanniocalcin ( STC ) is a homodimeric glycoprotein hormone implicated in calcium and phosphate regulation in both teleost fish and mammals ."
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"offsets": [
[
0,
141
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]
}
] |
[
{
"id": "split_0_train_47771_entity",
"type": "progene_text",
"text": [
"Stanniocalcin"
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"offsets": [
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0,
13
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{
"id": "split_0_train_47772_entity",
"type": "progene_text",
"text": [
"STC"
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"offsets": [
[
16,
19
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],
"normalized": []
}
] |
[] |
[] |
[] |
split_0_train_29686
|
split_0_train_29686
|
[
{
"id": "split_0_train_29686_passage",
"type": "progene_text",
"text": [
"In the present study , immunostaining with salmon STC antiserum demonstrated that STC cells were localized in both the corpuscles of Stannius ( CS ) and in specific cells of the distal renal tubules of the silver arawana , Osteoglossum bicirrhosum , an ancient ray - finned fish ( actinoptergian ) and basal teleost ( Order Osteoglossiforme ) ."
],
"offsets": [
[
0,
344
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]
}
] |
[
{
"id": "split_0_train_47773_entity",
"type": "progene_text",
"text": [
"STC"
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"offsets": [
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50,
53
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{
"id": "split_0_train_47774_entity",
"type": "progene_text",
"text": [
"STC"
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"offsets": [
[
82,
85
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"normalized": []
}
] |
[] |
[] |
[] |
split_0_train_29687
|
split_0_train_29687
|
[
{
"id": "split_0_train_29687_passage",
"type": "progene_text",
"text": [
"The morphology of these STC - immunoreactive kidney cells was similar to renal 'chloride' ( mitochondrial - rich ) cells ."
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"offsets": [
[
0,
122
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]
}
] |
[
{
"id": "split_0_train_47775_entity",
"type": "progene_text",
"text": [
"STC"
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"offsets": [
[
24,
27
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"normalized": []
}
] |
[] |
[] |
[] |
split_0_train_29688
|
split_0_train_29688
|
[
{
"id": "split_0_train_29688_passage",
"type": "progene_text",
"text": [
"The immunoreactive renal cells were present in two of three other osteoglossiformes and absent in the gar , a nonteleost actinopterygian and the eel , another basal teleost ."
],
"offsets": [
[
0,
174
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]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29689
|
split_0_train_29689
|
[
{
"id": "split_0_train_29689_passage",
"type": "progene_text",
"text": [
"The arawana STC cDNA encodes a prehormone of 249 amino acids ( aa ) with a signal peptide of 31 aa and a mature protein of 218 aa ."
],
"offsets": [
[
0,
131
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]
}
] |
[
{
"id": "split_0_train_47776_entity",
"type": "progene_text",
"text": [
"STC"
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"offsets": [
[
12,
15
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"normalized": []
}
] |
[] |
[] |
[] |
split_0_train_29690
|
split_0_train_29690
|
[
{
"id": "split_0_train_29690_passage",
"type": "progene_text",
"text": [
"The deduced aa sequence of arawana STC shows 54 - 66 % identity with other teleost STCs and 51 - 52 % identity with mammalian STC-1 ."
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"offsets": [
[
0,
133
]
]
}
] |
[
{
"id": "split_0_train_47777_entity",
"type": "progene_text",
"text": [
"STC"
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"offsets": [
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35,
38
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{
"id": "split_0_train_47778_entity",
"type": "progene_text",
"text": [
"STCs"
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83,
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},
{
"id": "split_0_train_47779_entity",
"type": "progene_text",
"text": [
"STC-1"
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"offsets": [
[
126,
131
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"normalized": []
}
] |
[] |
[] |
[] |
split_0_train_29691
|
split_0_train_29691
|
[
{
"id": "split_0_train_29691_passage",
"type": "progene_text",
"text": [
"The deduced aa sequence of arawana STC contains ten cysteines , compared with 11 in teleost STC and in mammalian STC-1 ."
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"offsets": [
[
0,
120
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]
}
] |
[
{
"id": "split_0_train_47780_entity",
"type": "progene_text",
"text": [
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35,
38
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{
"id": "split_0_train_47781_entity",
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92,
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},
{
"id": "split_0_train_47782_entity",
"type": "progene_text",
"text": [
"STC-1"
],
"offsets": [
[
113,
118
]
],
"normalized": []
}
] |
[] |
[] |
[] |
split_0_train_29692
|
split_0_train_29692
|
[
{
"id": "split_0_train_29692_passage",
"type": "progene_text",
"text": [
"The cysteine substitution occurs at the site of inter - monomeric disulfide linkage ."
],
"offsets": [
[
0,
85
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29693
|
split_0_train_29693
|
[
{
"id": "split_0_train_29693_passage",
"type": "progene_text",
"text": [
"Western blot analysis revealed a single 21 kDa band under non - reducing conditions , and a single band of 25 kDa under reducing conditions ."
],
"offsets": [
[
0,
141
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29694
|
split_0_train_29694
|
[
{
"id": "split_0_train_29694_passage",
"type": "progene_text",
"text": [
"These data indicate that arawana STC exists as a monomeric peptide ."
],
"offsets": [
[
0,
68
]
]
}
] |
[
{
"id": "split_0_train_47783_entity",
"type": "progene_text",
"text": [
"STC"
],
"offsets": [
[
33,
36
]
],
"normalized": []
}
] |
[] |
[] |
[] |
split_0_train_29695
|
split_0_train_29695
|
[
{
"id": "split_0_train_29695_passage",
"type": "progene_text",
"text": [
"Northern blot analysis detected a 3.3 kb STC mRNA confined to the CS , with no hybridization signal in either the remaining kidney or in gut , muscle , brain and heart ."
],
"offsets": [
[
0,
169
]
]
}
] |
[
{
"id": "split_0_train_47784_entity",
"type": "progene_text",
"text": [
"STC"
],
"offsets": [
[
41,
44
]
],
"normalized": []
}
] |
[] |
[] |
[] |
split_0_train_29696
|
split_0_train_29696
|
[
{
"id": "split_0_train_29696_passage",
"type": "progene_text",
"text": [
"The significance of the STC signal in cells of the renal tubules of arawana and two other Osteoglossiforme species requires further investigation ."
],
"offsets": [
[
0,
147
]
]
}
] |
[
{
"id": "split_0_train_47785_entity",
"type": "progene_text",
"text": [
"STC"
],
"offsets": [
[
24,
27
]
],
"normalized": []
}
] |
[] |
[] |
[] |
split_0_train_29697
|
split_0_train_29697
|
[
{
"id": "split_0_train_29697_passage",
"type": "progene_text",
"text": [
"This is the first report of a monomeric form of STC in any vertebrate and the first evidence of STC in renal tubules of adult fish ."
],
"offsets": [
[
0,
132
]
]
}
] |
[
{
"id": "split_0_train_47786_entity",
"type": "progene_text",
"text": [
"STC"
],
"offsets": [
[
48,
51
]
],
"normalized": []
},
{
"id": "split_0_train_47787_entity",
"type": "progene_text",
"text": [
"STC"
],
"offsets": [
[
96,
99
]
],
"normalized": []
}
] |
[] |
[] |
[] |
split_0_train_29698
|
split_0_train_29698
|
[
{
"id": "split_0_train_29698_passage",
"type": "progene_text",
"text": [
"[ Adhesion of composite to dentin. Mechanical and clinical results ]"
],
"offsets": [
[
0,
68
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_29699
|
split_0_train_29699
|
[
{
"id": "split_0_train_29699_passage",
"type": "progene_text",
"text": [
"Although an efficient bond of resin composites to enamel can be realized since quite a long time , reliable dentine bonding is nowadays still a clinical problem ."
],
"offsets": [
[
0,
162
]
]
}
] |
[] |
[] |
[] |
[] |
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