id
stringlengths 15
19
| document_id
stringlengths 15
19
| passages
list | entities
list | events
list | coreferences
list | relations
list |
|---|---|---|---|---|---|---|
split_0_train_5500
|
split_0_train_5500
|
[
{
"id": "split_0_train_5500_passage",
"type": "progene_text",
"text": [
"The critical load data are analyzed with the use of explicit fracture - mechanics relations , expressible in terms of routinely measurable material parameters ( elastic modulus , strength , toughness , hardness ) and essential geometrical variables ( layer thickness , contact radius ) ."
],
"offsets": [
[
0,
287
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5501
|
split_0_train_5501
|
[
{
"id": "split_0_train_5501_passage",
"type": "progene_text",
"text": [
"The utility of such analyses in the design of ceramic / substrate bilayer systems for optimal resistance to lifetime - threatening damage is discussed ."
],
"offsets": [
[
0,
152
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5502
|
split_0_train_5502
|
[
{
"id": "split_0_train_5502_passage",
"type": "progene_text",
"text": [
"Development of an exercise self - efficacy questionnaire for older Mexican American women ."
],
"offsets": [
[
0,
91
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5503
|
split_0_train_5503
|
[
{
"id": "split_0_train_5503_passage",
"type": "progene_text",
"text": [
"The purpose of this study was to develop a reliable and culturally meaningful exercise self - efficacy questionnaire for older Mexican American women ."
],
"offsets": [
[
0,
151
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5504
|
split_0_train_5504
|
[
{
"id": "split_0_train_5504_passage",
"type": "progene_text",
"text": [
"Items were derived from a 5 - item exercise self - efficacy instrument ( Laffrey , 2000 ; Marcus , Selby , Niaura , & Rossi , 1992 ) and from focus groups with women in the target population ."
],
"offsets": [
[
0,
192
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5505
|
split_0_train_5505
|
[
{
"id": "split_0_train_5505_passage",
"type": "progene_text",
"text": [
"Content validity of the Spanish - language items was supported by three Mexican American professional women and by five Mexican American nurses ."
],
"offsets": [
[
0,
145
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5506
|
split_0_train_5506
|
[
{
"id": "split_0_train_5506_passage",
"type": "progene_text",
"text": [
"A factor analysis of the 11-item questionnaire revealed one major factor ."
],
"offsets": [
[
0,
74
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5507
|
split_0_train_5507
|
[
{
"id": "split_0_train_5507_passage",
"type": "progene_text",
"text": [
"Internal consistency was shown by an alpha reliability coefficient of .86 ."
],
"offsets": [
[
0,
75
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5508
|
split_0_train_5508
|
[
{
"id": "split_0_train_5508_passage",
"type": "progene_text",
"text": [
"Item : corrected scale correlation coefficients ranged from .30 to .70 ."
],
"offsets": [
[
0,
72
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5509
|
split_0_train_5509
|
[
{
"id": "split_0_train_5509_passage",
"type": "progene_text",
"text": [
"The mean exercise self - efficacy score was significantly higher for 38 regular exercisers than for 37 non - exercisers ."
],
"offsets": [
[
0,
121
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5510
|
split_0_train_5510
|
[
{
"id": "split_0_train_5510_passage",
"type": "progene_text",
"text": [
"The exercise self - efficacy questionnaire can be used in research with older Mexican American women and should be tested with men and with younger men and women to explore its usefulness with these populations ."
],
"offsets": [
[
0,
212
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5511
|
split_0_train_5511
|
[
{
"id": "split_0_train_5511_passage",
"type": "progene_text",
"text": [
"Influence of sample preparation , staining procedure and analysis conditions on bull sperm head morphometry using the morphology analyser integrated visual optical system ."
],
"offsets": [
[
0,
172
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5512
|
split_0_train_5512
|
[
{
"id": "split_0_train_5512_passage",
"type": "progene_text",
"text": [
"The importance of standardizing the procedures of sample and slide preparation for computer - assisted morphologic analysis has been emphasized in human and veterinary andrology ."
],
"offsets": [
[
0,
179
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5513
|
split_0_train_5513
|
[
{
"id": "split_0_train_5513_passage",
"type": "progene_text",
"text": [
"The purpose of this study was to optimize slide preparation ( dilution grade and sperm washing ) , staining procedures and analysis conditions ( colour of light source and objective magnification ) for the morphometric analysis of bull spermatozoa using the Hamilton Thorne morphology analyzer integrated visual optical system ( IVOS ) ."
],
"offsets": [
[
0,
337
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5514
|
split_0_train_5514
|
[
{
"id": "split_0_train_5514_passage",
"type": "progene_text",
"text": [
"For experiment 1 , one ejaculate was collected from one bull and diluted to 200,000-300,000 spermatozoa / microl ."
],
"offsets": [
[
0,
114
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5515
|
split_0_train_5515
|
[
{
"id": "split_0_train_5515_passage",
"type": "progene_text",
"text": [
"Slides were prepared and stained using seven different procedures : rapid Papanicolaou ( PAP ) , rapid Papanicolaou with prolonged staining times ( PAP+) ."
],
"offsets": [
[
0,
155
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5516
|
split_0_train_5516
|
[
{
"id": "split_0_train_5516_passage",
"type": "progene_text",
"text": [
"Diff - Quik ( DIF ) , haematoxylin ( HEM ) ."
],
"offsets": [
[
0,
44
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5517
|
split_0_train_5517
|
[
{
"id": "split_0_train_5517_passage",
"type": "progene_text",
"text": [
"Farelly ( FAR ) , Spermac ( SPER ) and the modified GZIN ( MGZIN ) staining ."
],
"offsets": [
[
0,
77
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5518
|
split_0_train_5518
|
[
{
"id": "split_0_train_5518_passage",
"type": "progene_text",
"text": [
"All slides were analysed using a Hamilton Thorne Morphology Analyser IVOS equipped alternatively with a red , green or blue light source , and a 40x or 100x oil immersion objective ."
],
"offsets": [
[
0,
182
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5519
|
split_0_train_5519
|
[
{
"id": "split_0_train_5519_passage",
"type": "progene_text",
"text": [
"Recognition and digitization errors as well as morphometric parameters were determined ."
],
"offsets": [
[
0,
88
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5520
|
split_0_train_5520
|
[
{
"id": "split_0_train_5520_passage",
"type": "progene_text",
"text": [
"The IVOS was unable to detect DIF - stained spermatozoa ."
],
"offsets": [
[
0,
57
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5521
|
split_0_train_5521
|
[
{
"id": "split_0_train_5521_passage",
"type": "progene_text",
"text": [
"The GZIN and the SPER staining as well as the blue light source led to unsatisfactory results ."
],
"offsets": [
[
0,
95
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5522
|
split_0_train_5522
|
[
{
"id": "split_0_train_5522_passage",
"type": "progene_text",
"text": [
"Among the staining methods examined , the FAR , HEM , PAP + , and PAP staining , preferably in combination with the green light source , and the 40x objective yielded optimal results concerning sperm recognition and digitization ."
],
"offsets": [
[
0,
230
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5523
|
split_0_train_5523
|
[
{
"id": "split_0_train_5523_passage",
"type": "progene_text",
"text": [
"The 100x objective did not allow reliable analysis of the sperm heads because of a frequently appearing digitization error ."
],
"offsets": [
[
0,
124
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5524
|
split_0_train_5524
|
[
{
"id": "split_0_train_5524_passage",
"type": "progene_text",
"text": [
"For experiment 2 , three ejaculates were collected from each of three bulls and diluted to five dilution grades ( 100 000 - 500 000 spermatozoa / microl ) ."
],
"offsets": [
[
0,
156
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5525
|
split_0_train_5525
|
[
{
"id": "split_0_train_5525_passage",
"type": "progene_text",
"text": [
"An aliquot of each dilution grade was washed additionally ."
],
"offsets": [
[
0,
59
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5526
|
split_0_train_5526
|
[
{
"id": "split_0_train_5526_passage",
"type": "progene_text",
"text": [
"The percentage of correctly digitized sperm heads decreased with increasing spermatozoal concentration ."
],
"offsets": [
[
0,
104
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5527
|
split_0_train_5527
|
[
{
"id": "split_0_train_5527_passage",
"type": "progene_text",
"text": [
"However , the evaluation speed increased ."
],
"offsets": [
[
0,
42
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5528
|
split_0_train_5528
|
[
{
"id": "split_0_train_5528_passage",
"type": "progene_text",
"text": [
"The range of 200 000 - 300 000 spermatozoa / microl appeared to be a reasonable compromise for both criteria ."
],
"offsets": [
[
0,
110
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5529
|
split_0_train_5529
|
[
{
"id": "split_0_train_5529_passage",
"type": "progene_text",
"text": [
"Sperm washing failed to further improve the analysis results ."
],
"offsets": [
[
0,
62
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5530
|
split_0_train_5530
|
[
{
"id": "split_0_train_5530_passage",
"type": "progene_text",
"text": [
"Sperm head dimensions were influenced significantly by all variations of the methods in both experiments ."
],
"offsets": [
[
0,
106
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5531
|
split_0_train_5531
|
[
{
"id": "split_0_train_5531_passage",
"type": "progene_text",
"text": [
"In conclusion , using the proposed methods , the IVOS allows precise and reliable morphometric analyses of bull spermatozoa ."
],
"offsets": [
[
0,
125
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5532
|
split_0_train_5532
|
[
{
"id": "split_0_train_5532_passage",
"type": "progene_text",
"text": [
"The consistent application of these procedures may lead to an inter - laboratory standardization and to further establishment of generally accepted morphometric criteria used in human andrology ( e.g. World Health Organisation or strict criteria ) ."
],
"offsets": [
[
0,
249
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5533
|
split_0_train_5533
|
[
{
"id": "split_0_train_5533_passage",
"type": "progene_text",
"text": [
"Comparison of propolis skin cream to silver sulfadiazine : a naturopathic alternative to antibiotics in treatment of minor burns ."
],
"offsets": [
[
0,
130
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5534
|
split_0_train_5534
|
[
{
"id": "split_0_train_5534_passage",
"type": "progene_text",
"text": [
"BACKGROUND :"
],
"offsets": [
[
0,
12
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5535
|
split_0_train_5535
|
[
{
"id": "split_0_train_5535_passage",
"type": "progene_text",
"text": [
"Propolis , a naturopathic substance derived from bees wax extract , has recently been praised for its antimicrobial , anti - inflammatory , and cicatrization - enhancing properties ."
],
"offsets": [
[
0,
182
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5536
|
split_0_train_5536
|
[
{
"id": "split_0_train_5536_passage",
"type": "progene_text",
"text": [
"OBJECTIVE :"
],
"offsets": [
[
0,
11
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5537
|
split_0_train_5537
|
[
{
"id": "split_0_train_5537_passage",
"type": "progene_text",
"text": [
"In our study , we compare these properties in a high - grade Brazilian propolis skin cream directly with silver sulfadiazene ( SSD ) in the treatment of minor burns ( superficial second degree ) in the ambulatory care setting ( less than 20 % total body surface area burned ) ."
],
"offsets": [
[
0,
277
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5538
|
split_0_train_5538
|
[
{
"id": "split_0_train_5538_passage",
"type": "progene_text",
"text": [
"SETTINGS / LOCATION :"
],
"offsets": [
[
0,
21
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5539
|
split_0_train_5539
|
[
{
"id": "split_0_train_5539_passage",
"type": "progene_text",
"text": [
"The study was conducted at the burn clinic in Pronto Socorro para Queimaduras , Gioania , Brazil ."
],
"offsets": [
[
0,
98
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5540
|
split_0_train_5540
|
[
{
"id": "split_0_train_5540_passage",
"type": "progene_text",
"text": [
"SUBJECT :"
],
"offsets": [
[
0,
9
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5541
|
split_0_train_5541
|
[
{
"id": "split_0_train_5541_passage",
"type": "progene_text",
"text": [
"Patients were admitted to the study only if their initial presentation for burn care was within 48 hours postinjury and if bilateral wounds of similar depth and quality were present ."
],
"offsets": [
[
0,
183
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5542
|
split_0_train_5542
|
[
{
"id": "split_0_train_5542_passage",
"type": "progene_text",
"text": [
"INTERVENTIONS :"
],
"offsets": [
[
0,
15
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5543
|
split_0_train_5543
|
[
{
"id": "split_0_train_5543_passage",
"type": "progene_text",
"text": [
"Patients had propolis skin cream applied to one wound and SSD applied to the other selected wound on initial presentation and underwent debridement and dressings change the following morning ."
],
"offsets": [
[
0,
192
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5544
|
split_0_train_5544
|
[
{
"id": "split_0_train_5544_passage",
"type": "progene_text",
"text": [
"Patients subsequently returned to the clinic every 3 days to have the wounds checked and dressings changed ."
],
"offsets": [
[
0,
108
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5545
|
split_0_train_5545
|
[
{
"id": "split_0_train_5545_passage",
"type": "progene_text",
"text": [
"At these check - ups , wounds were cultured for microbial growth and photographed to document inflammation and cicatrization ."
],
"offsets": [
[
0,
126
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5546
|
split_0_train_5546
|
[
{
"id": "split_0_train_5546_passage",
"type": "progene_text",
"text": [
"Patients were instructed not to disturb their wounds or change their dressings at home , thus propolis skin cream and SSD were applied to the wounds only at the specified 3 - day intervals ."
],
"offsets": [
[
0,
190
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5547
|
split_0_train_5547
|
[
{
"id": "split_0_train_5547_passage",
"type": "progene_text",
"text": [
"RESULTS :"
],
"offsets": [
[
0,
9
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5548
|
split_0_train_5548
|
[
{
"id": "split_0_train_5548_passage",
"type": "progene_text",
"text": [
"Our preliminary results do not show any significant difference in microbial colonization between wounds treated with SSD and propolis skin cream , however , wounds treated with propolis skin cream consistently showed less inflammation and more rapid cicatrization then those treated with SSD ."
],
"offsets": [
[
0,
293
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5549
|
split_0_train_5549
|
[
{
"id": "split_0_train_5549_passage",
"type": "progene_text",
"text": [
"CONCLUSION :"
],
"offsets": [
[
0,
12
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5550
|
split_0_train_5550
|
[
{
"id": "split_0_train_5550_passage",
"type": "progene_text",
"text": [
"Propolis skin cream appears to have a beneficial effects on the healing of partial thickness burn wounds ."
],
"offsets": [
[
0,
106
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5551
|
split_0_train_5551
|
[
{
"id": "split_0_train_5551_passage",
"type": "progene_text",
"text": [
"If dressings had been changed more frequent the antimicrobial and wound healing effects would have been enhanced ."
],
"offsets": [
[
0,
114
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5552
|
split_0_train_5552
|
[
{
"id": "split_0_train_5552_passage",
"type": "progene_text",
"text": [
"Role of the rodent hippocampus in paired - associate learning involving associations between a stimulus and a spatial location ."
],
"offsets": [
[
0,
128
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5553
|
split_0_train_5553
|
[
{
"id": "split_0_train_5553_passage",
"type": "progene_text",
"text": [
"The ability of rats with control or hippocampal lesions to learn an object - place , odor - place , or object - odor paired - associate task was assessed in a cheeseboard maze apparatus ."
],
"offsets": [
[
0,
187
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5554
|
split_0_train_5554
|
[
{
"id": "split_0_train_5554_passage",
"type": "progene_text",
"text": [
"The data indicate that rats with hippocampal lesions were significantly impaired , compared with controls , in learning both the object - place and the odor - place paired - associate tasks ."
],
"offsets": [
[
0,
191
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5555
|
split_0_train_5555
|
[
{
"id": "split_0_train_5555_passage",
"type": "progene_text",
"text": [
"However , rats with hippocampal lesions learned the object - odor paired - associate task as readily as did controls ."
],
"offsets": [
[
0,
118
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5556
|
split_0_train_5556
|
[
{
"id": "split_0_train_5556_passage",
"type": "progene_text",
"text": [
"The data suggest that the rodent hippocampus is involved in paired - associate learning when a stimulus must be associated with a spatial location ."
],
"offsets": [
[
0,
148
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5557
|
split_0_train_5557
|
[
{
"id": "split_0_train_5557_passage",
"type": "progene_text",
"text": [
"However , the hippocampus is not involved in paired - associate learning when the association does not involve a spatial component ."
],
"offsets": [
[
0,
132
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5558
|
split_0_train_5558
|
[
{
"id": "split_0_train_5558_passage",
"type": "progene_text",
"text": [
"Nucleus basalis of Meynert pathology in the human brain after fatal head injury ."
],
"offsets": [
[
0,
81
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5559
|
split_0_train_5559
|
[
{
"id": "split_0_train_5559_passage",
"type": "progene_text",
"text": [
"Dysfunction of the basal forebrain cholinergic system has been hypothesized to contribute to deficits of memory and cognition after head injury ."
],
"offsets": [
[
0,
145
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5560
|
split_0_train_5560
|
[
{
"id": "split_0_train_5560_passage",
"type": "progene_text",
"text": [
"We have previously reported reduced levels of choline acetyltransferase activity in the cerebral cortex of patients who died after a head injury , demonstrating that there is a loss of cortical cholinergic innervation ."
],
"offsets": [
[
0,
219
]
]
}
] |
[
{
"id": "split_0_train_8542_entity",
"type": "progene_text",
"text": [
"choline acetyltransferase"
],
"offsets": [
[
46,
71
]
],
"normalized": []
}
] |
[] |
[] |
[] |
split_0_train_5561
|
split_0_train_5561
|
[
{
"id": "split_0_train_5561_passage",
"type": "progene_text",
"text": [
"In the present study , we examined the nucleus basalis of Meynert ( NBM ) , which provides cortical cholinergic innervation , in fatally head - injured patients and in controls ."
],
"offsets": [
[
0,
178
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5562
|
split_0_train_5562
|
[
{
"id": "split_0_train_5562_passage",
"type": "progene_text",
"text": [
"The majority of head - injured patients had histological evidence of neuronal damage in the NBM , which was due to mechanical distortion of the tissue and/or ischemic damage ."
],
"offsets": [
[
0,
175
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5563
|
split_0_train_5563
|
[
{
"id": "split_0_train_5563_passage",
"type": "progene_text",
"text": [
"The findings demonstrate that the NBM is vulnerable after severe head injury and that secondary insults play an important role in the damage ."
],
"offsets": [
[
0,
142
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5564
|
split_0_train_5564
|
[
{
"id": "split_0_train_5564_passage",
"type": "progene_text",
"text": [
"Thus , both neuronal perikarya and terminals of the basal forebrain cholinergic system are damaged after human fatal head injury ."
],
"offsets": [
[
0,
130
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5565
|
split_0_train_5565
|
[
{
"id": "split_0_train_5565_passage",
"type": "progene_text",
"text": [
"This damage may contribute to persisting dysfunction of memory and cognition in head - injured patients who survive ."
],
"offsets": [
[
0,
117
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5566
|
split_0_train_5566
|
[
{
"id": "split_0_train_5566_passage",
"type": "progene_text",
"text": [
"Factors influencing variability in load forces in a tripod grasp ."
],
"offsets": [
[
0,
66
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5567
|
split_0_train_5567
|
[
{
"id": "split_0_train_5567_passage",
"type": "progene_text",
"text": [
"The aim of this investigation was to determine the factors that influence the variability in the load force during a precision grip ."
],
"offsets": [
[
0,
133
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5568
|
split_0_train_5568
|
[
{
"id": "split_0_train_5568_passage",
"type": "progene_text",
"text": [
"Subjects grasped an object with three coarse contact surfaces using a tripod grasp of the thumb , index and middle fingers ."
],
"offsets": [
[
0,
124
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5569
|
split_0_train_5569
|
[
{
"id": "split_0_train_5569_passage",
"type": "progene_text",
"text": [
"The orientations of the contact surfaces and their locations relative to the object 's center of mass were varied ."
],
"offsets": [
[
0,
115
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5570
|
split_0_train_5570
|
[
{
"id": "split_0_train_5570_passage",
"type": "progene_text",
"text": [
"Forces and torques exerted by each of the three digits were measured or computed from the equilibrium conditions and analyzed during the static hold phase ."
],
"offsets": [
[
0,
156
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5571
|
split_0_train_5571
|
[
{
"id": "split_0_train_5571_passage",
"type": "progene_text",
"text": [
"The static load force depends on the object 's weight , but also on the precise location of the center of pressure of each digit , as well as on the magnitude of the tangential torque and horizontal grip force ."
],
"offsets": [
[
0,
211
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5572
|
split_0_train_5572
|
[
{
"id": "split_0_train_5572_passage",
"type": "progene_text",
"text": [
"Variations in these parameters caused deviations in the load forces by as much as 20 % or more from their nominal values ."
],
"offsets": [
[
0,
122
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5573
|
split_0_train_5573
|
[
{
"id": "split_0_train_5573_passage",
"type": "progene_text",
"text": [
"For the thumb , the largest source of variability was the vertical location of the center of pressure ."
],
"offsets": [
[
0,
103
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5574
|
split_0_train_5574
|
[
{
"id": "split_0_train_5574_passage",
"type": "progene_text",
"text": [
"For the two fingers , variations in the locations of the centers of pressure ( along the horizontal and vertical ) and in the magnitudes of the tangential torques had effects that were about equal in magnitude ."
],
"offsets": [
[
0,
211
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5575
|
split_0_train_5575
|
[
{
"id": "split_0_train_5575_passage",
"type": "progene_text",
"text": [
"Since many of the sources of variability in load force are unpredictable , these results point to the importance of online feedback regulation of grip force ."
],
"offsets": [
[
0,
158
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5576
|
split_0_train_5576
|
[
{
"id": "split_0_train_5576_passage",
"type": "progene_text",
"text": [
"The Calcimimetic agent AMG 073 lowers plasma parathyroid hormone levels in hemodialysis patients with secondary hyperparathyroidism ."
],
"offsets": [
[
0,
133
]
]
}
] |
[
{
"id": "split_0_train_8543_entity",
"type": "progene_text",
"text": [
"parathyroid hormone"
],
"offsets": [
[
45,
64
]
],
"normalized": []
}
] |
[] |
[] |
[] |
split_0_train_5577
|
split_0_train_5577
|
[
{
"id": "split_0_train_5577_passage",
"type": "progene_text",
"text": [
"Treatment with vitamin D sterols can lower plasma parathyroid hormone ( PTH ) in many patients with secondary hyperparathyroidism due to end - stage renal disease , but hypercalcemia , hyperphosphatemia , or both often develop during treatment ."
],
"offsets": [
[
0,
245
]
]
}
] |
[
{
"id": "split_0_train_8544_entity",
"type": "progene_text",
"text": [
"parathyroid hormone"
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"offsets": [
[
50,
69
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],
"normalized": []
},
{
"id": "split_0_train_8545_entity",
"type": "progene_text",
"text": [
"PTH"
],
"offsets": [
[
72,
75
]
],
"normalized": []
}
] |
[] |
[] |
[] |
split_0_train_5578
|
split_0_train_5578
|
[
{
"id": "split_0_train_5578_passage",
"type": "progene_text",
"text": [
"As such , alternative therapeutic approaches to managing excess PTH secretion are needed ."
],
"offsets": [
[
0,
90
]
]
}
] |
[
{
"id": "split_0_train_8546_entity",
"type": "progene_text",
"text": [
"PTH"
],
"offsets": [
[
64,
67
]
],
"normalized": []
}
] |
[] |
[] |
[] |
split_0_train_5579
|
split_0_train_5579
|
[
{
"id": "split_0_train_5579_passage",
"type": "progene_text",
"text": [
"Calcimimetic agents directly inhibit PTH secretion by activating the calcium - sensing receptor in the parathyroid glands , but clinical experience with them is limited ."
],
"offsets": [
[
0,
170
]
]
}
] |
[
{
"id": "split_0_train_8547_entity",
"type": "progene_text",
"text": [
"PTH"
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"offsets": [
[
37,
40
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],
"normalized": []
},
{
"id": "split_0_train_8548_entity",
"type": "progene_text",
"text": [
"calcium - sensing receptor"
],
"offsets": [
[
69,
95
]
],
"normalized": []
}
] |
[] |
[] |
[] |
split_0_train_5580
|
split_0_train_5580
|
[
{
"id": "split_0_train_5580_passage",
"type": "progene_text",
"text": [
"Fifty - two hemodialysis patients with secondary hyperparathyroidism were given single orally administered doses of the calcimimetic agent AMG 073 ranging from 5 to 100 mg , or placebo ."
],
"offsets": [
[
0,
186
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5581
|
split_0_train_5581
|
[
{
"id": "split_0_train_5581_passage",
"type": "progene_text",
"text": [
"Plasma PTH levels decreased 2 h after 25 - , 50 - , 75 - , or 100 - mg doses , falling by a maximum of 43 +/- 29 % , 40 +/- 36 % , 54 +/- 28 % , or 55 +/- 39 % , respectively ."
],
"offsets": [
[
0,
176
]
]
}
] |
[
{
"id": "split_0_train_8549_entity",
"type": "progene_text",
"text": [
"PTH"
],
"offsets": [
[
7,
10
]
],
"normalized": []
}
] |
[] |
[] |
[] |
split_0_train_5582
|
split_0_train_5582
|
[
{
"id": "split_0_train_5582_passage",
"type": "progene_text",
"text": [
"Plasma PTH levels decreased in all patients given doses of > or = 25 mg but did not change in those who received placebo ."
],
"offsets": [
[
0,
122
]
]
}
] |
[
{
"id": "split_0_train_8550_entity",
"type": "progene_text",
"text": [
"PTH"
],
"offsets": [
[
7,
10
]
],
"normalized": []
}
] |
[] |
[] |
[] |
split_0_train_5583
|
split_0_train_5583
|
[
{
"id": "split_0_train_5583_passage",
"type": "progene_text",
"text": [
"In patients treated with daily doses of 25 or 50 mg of AMG 073 for 8 d , plasma PTH levels declined for the first 3 to 4 d and remained below baseline values after 8 d of treatment ."
],
"offsets": [
[
0,
182
]
]
}
] |
[
{
"id": "split_0_train_8551_entity",
"type": "progene_text",
"text": [
"PTH"
],
"offsets": [
[
80,
83
]
],
"normalized": []
}
] |
[] |
[] |
[] |
split_0_train_5584
|
split_0_train_5584
|
[
{
"id": "split_0_train_5584_passage",
"type": "progene_text",
"text": [
"Serum calcium concentrations also decreased by 5 to 10 % from pretreatment levels in patients given 50 mg of AMG 073 for 8 d , but values were unchanged in those who received lower doses ."
],
"offsets": [
[
0,
188
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5585
|
split_0_train_5585
|
[
{
"id": "split_0_train_5585_passage",
"type": "progene_text",
"text": [
"Serum phosphorus levels and values for the calcium - phosphorus ion product both decreased after treatment with AMG 073 ."
],
"offsets": [
[
0,
121
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5586
|
split_0_train_5586
|
[
{
"id": "split_0_train_5586_passage",
"type": "progene_text",
"text": [
"Thus , 8 d of treatment with AMG 073 effectively lowers plasma PTH levels and improves several disturbances in mineral metabolism that have been associated with soft tissue and vascular calcification and with adverse cardiovascular outcomes in patients with end - stage renal disease ."
],
"offsets": [
[
0,
285
]
]
}
] |
[
{
"id": "split_0_train_8552_entity",
"type": "progene_text",
"text": [
"PTH"
],
"offsets": [
[
63,
66
]
],
"normalized": []
}
] |
[] |
[] |
[] |
split_0_train_5587
|
split_0_train_5587
|
[
{
"id": "split_0_train_5587_passage",
"type": "progene_text",
"text": [
"Independent regulation of the divergent Escherichia coli nrfA and acsP1 promoters by a nucleoprotein assembly at a shared regulatory region ."
],
"offsets": [
[
0,
141
]
]
}
] |
[
{
"id": "split_0_train_8553_entity",
"type": "progene_text",
"text": [
"nrfA"
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"offsets": [
[
57,
61
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],
"normalized": []
},
{
"id": "split_0_train_8554_entity",
"type": "progene_text",
"text": [
"acsP1"
],
"offsets": [
[
66,
71
]
],
"normalized": []
}
] |
[] |
[] |
[] |
split_0_train_5588
|
split_0_train_5588
|
[
{
"id": "split_0_train_5588_passage",
"type": "progene_text",
"text": [
"Expression from the Escherichia coli nrfA promoter ( pnrfA ) is activated by both the FNR protein ( an anaerobically triggered transcription activator ) and the NarL or NarP proteins ( transcription activators triggered by nitrite and nitrate ) ."
],
"offsets": [
[
0,
246
]
]
}
] |
[
{
"id": "split_0_train_8555_entity",
"type": "progene_text",
"text": [
"nrfA"
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"offsets": [
[
37,
41
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],
"normalized": []
},
{
"id": "split_0_train_8556_entity",
"type": "progene_text",
"text": [
"FNR"
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"offsets": [
[
86,
89
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],
"normalized": []
},
{
"id": "split_0_train_8557_entity",
"type": "progene_text",
"text": [
"NarL"
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"offsets": [
[
161,
165
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],
"normalized": []
},
{
"id": "split_0_train_8558_entity",
"type": "progene_text",
"text": [
"NarP"
],
"offsets": [
[
169,
173
]
],
"normalized": []
}
] |
[] |
[] |
[] |
split_0_train_5589
|
split_0_train_5589
|
[
{
"id": "split_0_train_5589_passage",
"type": "progene_text",
"text": [
"Under anaerobic conditions , FNR binds to a site centred at position - 41.5 at pnrfA and activates transcription ."
],
"offsets": [
[
0,
114
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]
}
] |
[
{
"id": "split_0_train_8559_entity",
"type": "progene_text",
"text": [
"FNR"
],
"offsets": [
[
29,
32
]
],
"normalized": []
}
] |
[] |
[] |
[] |
split_0_train_5590
|
split_0_train_5590
|
[
{
"id": "split_0_train_5590_passage",
"type": "progene_text",
"text": [
"Further activation , induced by the presence of nitrite , results from the binding of NarL and NarP to a site centred at position - 74.5 ."
],
"offsets": [
[
0,
138
]
]
}
] |
[
{
"id": "split_0_train_8560_entity",
"type": "progene_text",
"text": [
"NarL"
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"offsets": [
[
86,
90
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],
"normalized": []
},
{
"id": "split_0_train_8561_entity",
"type": "progene_text",
"text": [
"NarP"
],
"offsets": [
[
95,
99
]
],
"normalized": []
}
] |
[] |
[] |
[] |
split_0_train_5591
|
split_0_train_5591
|
[
{
"id": "split_0_train_5591_passage",
"type": "progene_text",
"text": [
"A second promoter ( pacsP1 ) , which directs transcription into the adjacent gene encoding acetyl coenzyme A synthetase ( acs ) , is overlapping and divergent to pnrfA ."
],
"offsets": [
[
0,
169
]
]
}
] |
[
{
"id": "split_0_train_8562_entity",
"type": "progene_text",
"text": [
"acetyl coenzyme A synthetase"
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"offsets": [
[
91,
119
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],
"normalized": []
},
{
"id": "split_0_train_8563_entity",
"type": "progene_text",
"text": [
"acs"
],
"offsets": [
[
122,
125
]
],
"normalized": []
}
] |
[] |
[] |
[] |
split_0_train_5592
|
split_0_train_5592
|
[
{
"id": "split_0_train_5592_passage",
"type": "progene_text",
"text": [
"Despite extensive overlap of regulatory elements , pnrfA and pacsP1 are regulated independently ."
],
"offsets": [
[
0,
97
]
]
}
] |
[] |
[] |
[] |
[] |
split_0_train_5593
|
split_0_train_5593
|
[
{
"id": "split_0_train_5593_passage",
"type": "progene_text",
"text": [
"We demonstrate that at least two nucleoid - associated factors bind to the nrfA - acs intergenic region ."
],
"offsets": [
[
0,
105
]
]
}
] |
[
{
"id": "split_0_train_8564_entity",
"type": "progene_text",
"text": [
"nrfA"
],
"offsets": [
[
75,
79
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],
"normalized": []
},
{
"id": "split_0_train_8565_entity",
"type": "progene_text",
"text": [
"acs"
],
"offsets": [
[
82,
85
]
],
"normalized": []
}
] |
[] |
[] |
[] |
split_0_train_5594
|
split_0_train_5594
|
[
{
"id": "split_0_train_5594_passage",
"type": "progene_text",
"text": [
"The Fis protein binds to a site centred at position - 15 ( in relation to pnrfA transcription ) , whereas the IHF protein binds to a site centred at position - 54 ."
],
"offsets": [
[
0,
164
]
]
}
] |
[
{
"id": "split_0_train_8566_entity",
"type": "progene_text",
"text": [
"Fis"
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"offsets": [
[
4,
7
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],
"normalized": []
},
{
"id": "split_0_train_8567_entity",
"type": "progene_text",
"text": [
"IHF"
],
"offsets": [
[
110,
113
]
],
"normalized": []
}
] |
[] |
[] |
[] |
split_0_train_5595
|
split_0_train_5595
|
[
{
"id": "split_0_train_5595_passage",
"type": "progene_text",
"text": [
"Both Fis and IHF repress in vivo expression from pacsP1 , but have smaller repressive effects on expression from pnrfA ."
],
"offsets": [
[
0,
120
]
]
}
] |
[
{
"id": "split_0_train_8568_entity",
"type": "progene_text",
"text": [
"Fis"
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"offsets": [
[
5,
8
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],
"normalized": []
},
{
"id": "split_0_train_8569_entity",
"type": "progene_text",
"text": [
"IHF"
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"offsets": [
[
13,
16
]
],
"normalized": []
}
] |
[] |
[] |
[] |
split_0_train_5596
|
split_0_train_5596
|
[
{
"id": "split_0_train_5596_passage",
"type": "progene_text",
"text": [
"Gel retardation assays were used to investigate the pairwise binding of FNR , NarL , Fis and IHF proteins to the nrfA - acs intergenic region ."
],
"offsets": [
[
0,
143
]
]
}
] |
[
{
"id": "split_0_train_8570_entity",
"type": "progene_text",
"text": [
"FNR"
],
"offsets": [
[
72,
75
]
],
"normalized": []
},
{
"id": "split_0_train_8571_entity",
"type": "progene_text",
"text": [
"NarL"
],
"offsets": [
[
78,
82
]
],
"normalized": []
},
{
"id": "split_0_train_8572_entity",
"type": "progene_text",
"text": [
"Fis"
],
"offsets": [
[
85,
88
]
],
"normalized": []
},
{
"id": "split_0_train_8573_entity",
"type": "progene_text",
"text": [
"IHF"
],
"offsets": [
[
93,
96
]
],
"normalized": []
},
{
"id": "split_0_train_8574_entity",
"type": "progene_text",
"text": [
"nrfA"
],
"offsets": [
[
113,
117
]
],
"normalized": []
},
{
"id": "split_0_train_8575_entity",
"type": "progene_text",
"text": [
"acs"
],
"offsets": [
[
120,
123
]
],
"normalized": []
}
] |
[] |
[] |
[] |
split_0_train_5597
|
split_0_train_5597
|
[
{
"id": "split_0_train_5597_passage",
"type": "progene_text",
"text": [
"The binding of NarL and IHF is mutually exclusive , whereas all other combinations can bind simultaneously ."
],
"offsets": [
[
0,
108
]
]
}
] |
[
{
"id": "split_0_train_8576_entity",
"type": "progene_text",
"text": [
"NarL"
],
"offsets": [
[
15,
19
]
],
"normalized": []
},
{
"id": "split_0_train_8577_entity",
"type": "progene_text",
"text": [
"IHF"
],
"offsets": [
[
24,
27
]
],
"normalized": []
}
] |
[] |
[] |
[] |
split_0_train_5598
|
split_0_train_5598
|
[
{
"id": "split_0_train_5598_passage",
"type": "progene_text",
"text": [
"Experiments in which deletions and point mutations were introduced into the upstream region of pnrfA demonstrated that an additional factor must bind upstream to inhibit FNR - dependent transcription ."
],
"offsets": [
[
0,
201
]
]
}
] |
[
{
"id": "split_0_train_8578_entity",
"type": "progene_text",
"text": [
"FNR"
],
"offsets": [
[
170,
173
]
],
"normalized": []
}
] |
[] |
[] |
[] |
split_0_train_5599
|
split_0_train_5599
|
[
{
"id": "split_0_train_5599_passage",
"type": "progene_text",
"text": [
"We conclude that the nrfA - acs intergenic region is folded into an ordered nucleoprotein structure that permits the two divergent promoters to be regulated independently in response to different physiological signals ."
],
"offsets": [
[
0,
219
]
]
}
] |
[
{
"id": "split_0_train_8579_entity",
"type": "progene_text",
"text": [
"nrfA"
],
"offsets": [
[
21,
25
]
],
"normalized": []
},
{
"id": "split_0_train_8580_entity",
"type": "progene_text",
"text": [
"acs"
],
"offsets": [
[
28,
31
]
],
"normalized": []
}
] |
[] |
[] |
[] |
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