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Line 166: define “devolved nations” for readers unfamiliar with the term.
| null | null |
What is surprising though is that 55.7% of the dogs who were reported to show SRB in February (before the pandemic) were clear in October which is good news.
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ani12040482_perova
| 0 |
Line 30: change “leaving hours increase again” to “time left alone increased again” Thank you, this edit has been applied.
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Results: These were generally well-detailed with clear layout considering scope of results.
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ani12040482_perova
| 0 |
It may be beneficial to make it clear why cut off of 'at least 5 mins' was used, e.g justification for this/why this time duration used.
| null | null |
The authors examined how separation-related behaviors in pet dogs changed in relation to time spent away from home by UK owners in February 2020 (pre-pandemic), May-July 2020 (first lockdown during the pandemic), and October-November 2020 (local tier-system for restrictions; follow-up).
| null | null |
ani12040482_perova
| 0 |
“More Attention than Usual”: A Thematic Analysis of Dog Ownership Experiences in the 530 UK during the First COVID-19 Lockdown. Anim. 2021, Vol. 11, Page 240 2021, 11, 240, doi:10.3390/ANI11010240).
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In other words, 1407/1807 (78%) of dogs were clear of SRB in February and 90.1% in October.
| null | null |
ani12040482_perova
| 0 |
An error message occurred in several places (e.g., line 131, line 246, line 265)
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Materials and Methods: Line 151: how was the criterion of “at least 5 minutes” chosen?
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ani12040482_perova
| 0 |
Lines 383-384: Change “dogs’ leaving routines” to “dogs’ time left alone” Thank you, this edit has been applied.
| null | null |
L118 Materials and Methods This section (after the Ethics) should begin with the Subjects section.
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ani12040482_perova
| 0 |
This information would have been interesting if data on the mood, stress level, general mental health of the owners had also been collected in connection with the pandemic and the links with dog behaviour have been investigated.
| null | null |
Author Response Thank you for your time in reviewing this manuscript and for your constructive, helpful feedback.
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ani12040482_perova
| 0 |
The authors examined how separation-related behaviors in pet dogs changed in relation to time spent away from home by UK owners in February 2020 (pre-pandemic), May-July 2020 (first lockdown during the pandemic), and October-November 2020 (local tier-system for restrictions; follow-up).
| null | null |
However, currently, the paper seems too long, and it goes into too much detail about how the pandemic took place in the UK.
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ani12040482_perova
| 0 |
The curve in the plot is not due to a compensation issue, it is demonstrating the up-regulation of CD36, which is followed by up-regulation of CD11b.
| null | null |
The manuscript is well written, the results support the hypotheses.
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antiox11040683_makarova
| 0 |
We have included what we have written below for your convenience: “The U937 cell line was originally isolated from the pleural effusion of a patient with histiocytic lymphoma [42].
| null | null |
Authors addressed all my requests and suggestions to my fullest satisfaction.
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antiox11040683_makarova
| 0 |
We have included what we have written below for your convenience: “The U937 cell line was originally isolated from the pleural effusion of a patient with histiocytic lymphoma [42].
| null | null |
We agree with your comments and have addressed these to the best of our ability in the revised manuscript.
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antiox11040683_makarova
| 0 |
Thus, authors should discuss limitations in interpreting their findings.
| null | null |
The black population illustrates the isotype control for the FITC and PE conjugated antibodies.
| null | null |
antiox11040683_makarova
| 0 |
Taken together, the U937 cell line presented as a good cellular model to study the putative antioxidant effect of the BCAT1 CXXC motif in myeloid differentiation, which is a defining feature of AML [50].
| null | null |
Taken together, the U937 cell line presented as a good cellular model to study the putative antioxidant effect of the BCAT1 CXXC motif in myeloid differentiation, which is a defining feature of AML [50].
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antiox11040683_makarova
| 0 |
10 + description) steady state inverstigation is acceptable.
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Author Response Thanks for your encouragement and suggestion.
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app12052642_perova
| 0 |
[19], this paper proposed a DL-LET joint by fixing a layer of flexible H18 aluminum foil a LET joint.
| null | null |
Author Response Thanks a lot for your encouragement and suggestion.
| null | null |
app12052642_perova
| 0 |
Author Response Thanks a lot for your encouragement and suggestion.
| null | null |
Chen, G.; Ma, F.; Hao, G.; Zhu, W. Modeling large deflections of initially curved beams in compliant mechanisms using 277 chained Beam-Constraint-Model, ASME J. Mech.
| null | null |
app12052642_perova
| 0 |
Robot., 2019, 11: 011002, https://doi.org/10.1115/1.4041585.
| null | null |
[19], this paper proposed a DL-LET joint by fixing a layer of flexible H18 aluminum foil a LET joint.
| null | null |
app12052642_perova
| 0 |
A theoretical model is derived for the DL-LET joint and verified by FEA and experimental results."
| null | null |
Author Response Thanks for your encouragement and suggestion.
| null | null |
app12052642_perova
| 0 |
Author Response Thanks a lot for your encouragement and suggestion.
| null | null |
[19], this paper proposed a DL-LET joint by fixing a layer of flexible H18 aluminum foil a LET joint.
| null | null |
app12052642_perova
| 0 |
10 + description) steady state inverstigation is acceptable.
| null | null |
At the beginning of the last paragraph of Introduction: "In this work, based on the design concept of improving the tensile stiffness of LET joints in Ref.
| null | null |
app12052642_perova
| 0 |
Following the reported physical experiments (Fig.
| null | null |
Author Response We thanks the reviewer for the encouragement and valuable comments.
| null | null |
app12052642_perova
| 0 |
The current paper proposes a novel lamina emergent torsional (LET) joint named double-laminated lamina emergent torsional joint (DL-LET) joint which utilizes a layer of flexible H18 aluminum foil to increase the tensile stiffness of LET joint.
| null | null |
Author Response We thanks the reviewer for the encouragement and valuable comments.
| null | null |
app12052642_perova
| 0 |
Following the reported physical experiments (Fig.
| null | null |
Chen, G.; Ma, F.; Hao, G.; Zhu, W. Modeling large deflections of initially curved beams in compliant mechanisms using 277 chained Beam-Constraint-Model, ASME J. Mech.
| null | null |
app12052642_perova
| 0 |
[19], this paper proposed a DL-LET joint by fixing a layer of flexible H18 aluminum foil a LET joint.
| null | null |
Robot., 2019, 11: 011002, https://doi.org/10.1115/1.4041585.
| null | null |
app12052642_perova
| 0 |
Following the reported physical experiments (Fig.
| null | null |
Nice piece of research but one aspect needs to be addressed.
| null | null |
app12052642_perova
| 0 |
Chen, G.; Ma, F.; Hao, G.; Zhu, W. Modeling large deflections of initially curved beams in compliant mechanisms using 277 chained Beam-Constraint-Model, ASME J. Mech.
| null | null |
The flow of the paper or the organization of the paper has to be presented at the end of the introductory section.
| null | null |
app12052642_perova
| 0 |
Author Response We thanks the reviewer for the encouragement and valuable comments.
| null | null |
Author Response Thanks a lot for your encouragement and suggestion.
| null | null |
app12052642_perova
| 0 |
10 + description) steady state inverstigation is acceptable.
| null | null |
Author Response Thanks a lot for your encouragement and suggestion.
| null | null |
app12052642_perova
| 0 |
Following the referee’s suggestion we have added the reference to Mekhov’s paper.
| null | null |
Concerning the question of radiationpressure forces, we take them into account on the atoms but not on the mirrors.
| null | null |
atoms4010002_makarova
| 0 |
(b) There will be heating limiting the available measurement time.
| null | null |
Also the BEC will lead to an effective change of the cavity length and lattice constant, which should renormalize the wavelength and thus om_recoil.
| null | null |
atoms4010002_makarova
| 0 |
Following the referee’s suggestion we have added the reference to Mekhov’s paper.
| null | null |
I support publication, but I have a few comments that the authors hopefully can address before publication.
| null | null |
atoms4010002_makarova
| 0 |
Author Response The authors present a new interpretation to study Bloch oscillations in a cavity sustained optical lattice and the potential use of this system for very sensitive force measurement.The idea is closely related to previous work as Ref.
| null | null |
Indeed, we point out a possible way forward in the last section that builds on the insight gained from the optomechanics analogy.
| null | null |
atoms4010002_makarova
| 0 |
The sensitivity of their measurements, after many years of development, are only one order of magnitude above our estimated sensitivity, and their measurements take one hour whereas ours should take one second which means it might have applications in rather different situations (e.g.
| null | null |
Nevertheless, the Bloch oscillation frequency is robust against this depth modulation because it only depends on the lattice period, not its depth.”
| null | null |
atoms4010002_makarova
| 0 |
However, a change in the depth of a periodic potential does not change the Bloch frequency because this depends on the lattice’s spatial period, not the depth.
| null | null |
(3) The authors claim there should be no backaction of the field on the oscillation frequencies.
| null | null |
atoms4010002_makarova
| 0 |
(3) The authors claim there should be no backaction of the field on the oscillation frequencies.
| null | null |
To my knowledge this was first discussed in: Gangl, M., EPJD, 8(1), 29-40.
| null | null |
atoms4010002_makarova
| 0 |
(2) It is very helpful to connect cavity output spectra and forces.
| null | null |
Author Response The authors present a new interpretation to study Bloch oscillations in a cavity sustained optical lattice and the potential use of this system for very sensitive force measurement.The idea is closely related to previous work as Ref.
| null | null |
atoms4010002_makarova
| 0 |
Some rough estimate on the time scales should be added.
| null | null |
Hence, in principle I consider it suitable for publication.There are however a few things to be clarified before publication:
| null | null |
atoms4010002_makarova
| 0 |
The auhtors investigate the motion of atoms in a periodic potential inside he cavity taking into account the effect of continuous measurement of photons leaking out of the cavity.
| null | null |
Nevertheless the presentaion sheds new light onto the underlying microscopic dynamics and connects the dynamics to proven optomechanical models of cavity BEC dynamics.
| null | null |
atoms4010002_perova
| 0 |
There are however a few things to be clarified before publication: (1) It should be somehow mentioned more clearly (maybe in the abstract) that the idea is not completely new but work presents a new and more intutive picture of the system dynamics.
| null | null |
Hence, in principle I consider it suitable for publication.
| null | null |
atoms4010002_perova
| 0 |
B: Atomic, Molecular and Optical Physics, 45(10), 102001).
| null | null |
Author Response The authors present a new interpretation to study Bloch oscillations in a cavity sustained optical lattice and the potential use of this system for very sensitive force measurement.The idea is closely related to previous work as Ref.
| null | null |
atoms4010002_perova
| 0 |
This will generate extra noise, but might also help as it reduces atom number uncertainty in the cavity.
| null | null |
Some rough estimate on the time scales should be added.
| null | null |
atoms4010002_perova
| 0 |
Rev. A 88, 033830 (2013). I. B. Mekhov and H. Ritsch, Phys. Rev. Lett. 102, 020403 (2009). J. F. Corney and G. J. Milburn, Phys. Rev. A 58, 2399 (1998). I. D. Leroux, M. H. Schleier-Smith, and V. Vuletić, Phys. Rev. Lett. 104, 073602 (2010).
| null | null |
The idea is closely related to previous work as Ref.
| null | null |
atoms4010002_perova
| 0 |
Rev. A 88, 033830 (2013). I. B. Mekhov and H. Ritsch, Phys. Rev. Lett. 102, 020403 (2009). J. F. Corney and G. J. Milburn, Phys. Rev. A 58, 2399 (1998). I. D. Leroux, M. H. Schleier-Smith, and V. Vuletić, Phys. Rev. Lett. 104, 073602 (2010).
| null | null |
Also the BEC will lead to an effective change of the cavity length and lattice constant, which should renormalize the wavelength and thus om_recoil.
| null | null |
atoms4010002_perova
| 0 |
Hence, in principle I consider it suitable for publication.There are however a few things to be clarified before publication:
| null | null |
Hence, in principle I consider it suitable for publication.There are however a few things to be clarified before publication:
| null | null |
atoms4010002_perova
| 0 |
M. D. Lee, S. Rist, and J. Ruostekoski, New J. Phys. 14, 073057 (2012).
| null | null |
This is somehow in contradiction with theeigenfrequency calculations (see Fig.4) in Horak, P.,Physical Review A, 61(3), 033609, 2000.
| null | null |
atoms4010002_perova
| 0 |
· Line 138: insert “the” before “TDCS” also inserting “even at relativistic energies” would strengthen this intent of this work · Line 139: reference 30 should be replaced with a theoretical reference or the text changed to not imply that ref 30 is a theoretical work · Line 140: delete “one” and insert “the” before “non” plus change “that this would enhance” to “this enhances” Also lines 141-143 are probably meant to be a single sentence.
| null | null |
Also, round the numbers in Fig 6 to whole keV units.
| null | null |
atoms4010010_makarova
| 0 |
The main point in this work is to theoretically study relativistic ionization.
| null | null |
Again, we appreciate all your insightful comments.
| null | null |
atoms4010010_makarova
| 0 |
At least the authors should mention the differences of the two methods and how far the RPWBA can be compared to rDWBA?
| null | null |
-------------------------------------------------------------------------------------------------------------------------- Page 1: * Line 7: it is referenced to the recent theories given in [2] and [3] which are from years 1994 and 2002 respectively.
| null | null |
atoms4010010_makarova
| 0 |
Author Response %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% Answer to the third referee’s report of the Manuscript ID atoms-114670 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% The article presents triple differential cross sections (tdcs) calculations of hydrogen ionization by positron and electron impact, in the relativistic and non-relativistic limit, using relativistic plane-wave Born approximation and non relativistic approximations.
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Explanation of the differences between the peaks corresponding to the different projectiles is given.
| null | null |
atoms4010010_makarova
| 0 |
The authors did not mention these experimental works in the manuscript.
| null | null |
· Line 129: insert “the” before “TDCS” · Table 2: number notation · Line 134: replace “by” with “with” · Lines 135-137: delete this sentence as it says exactly the same as the previous sentence and Table 2.
| null | null |
atoms4010010_makarova
| 0 |
Also, round the numbers in Fig 6 to whole keV units.
| null | null |
Evidences of this includes (i) some errors in English typing, e.g.
| null | null |
atoms4010010_makarova
| 0 |
Author Response %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% Answer to the first referee’s report of the Manuscript ID atoms-114670 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% In the paper, the authors report the theoretical calculation of triple differential cross sections of positron ionization of hydrogen atom at relativistic regime to understand the collision dynamics.
| null | null |
My overall recommendation is that after the listed items are addressed the manuscript be accepted for publication without further review.
| null | null |
atoms4010010_perova
| 0 |
------------------------------------------- Thank you once again for your valuable comments and corrections.
| null | null |
------------------------------------------- Thank you once again for your valuable comments and corrections.
| null | null |
atoms4010010_perova
| 0 |
------------------------------- Answer of authors ------------------------------- - First of all, we would like to thank you very much for this relevant and detailed report.
| null | null |
The following issues need to be addressed: 1)
| null | null |
atoms4010010_perova
| 0 |
I find no major problems with the manuscript, either in content or presentation.
| null | null |
In my opinion, the primary contribution of this work is the prediction that even at relativistic velocities, the TDCS for positron impact is larger than for electron impact and that the difference increases with impact energy.
| null | null |
atoms4010010_perova
| 0 |
------------------------------- 1) Answer of authors -------------------------------
| null | null |
Although no experimental data are available for comparison, the method is well explained and reported to agree with other electron impact calculations.
| null | null |
atoms4010010_perova
| 0 |
Two processes are considered, one occurs during the interaction between the cold atom cloud and the Raman beams, the other occurs during the free evolution of the cold atom cloud in vacuum.
| null | null |
Review Report 2 In this manuscript, the influences of an external test mass on the phase of the signal of an atom interferometer are studied theoretically.
| null | null |
atoms4020014_perova
| 0 |
1 Review Report 1 Originality/Novelty This paper treats an important question concerning the measurement of the gravitational constant G by atom interferometry.
| null | null |
The correction phi_Q was not discussed in the previous papers I know on the subject and I think that the paper must be published but, as explained below, important improvements are needed.
| null | null |
atoms4020014_perova
| 0 |
Authors’ response We would like to thank the referee for his/her careful reading of the manuscript and the helpful comments.
| null | null |
Review Report 2 In this manuscript, the influences of an external test mass on the phase of the signal of an atom interferometer are studied theoretically.
| null | null |
atoms4020014_perova
| 0 |
The response to these comments and changes to the manuscript in response to these comments is given below: 1.
| null | null |
The correction phi_Q was not discussed in the previous papers I know on the subject and I think that the paper must be published but, as explained below, important improvements are needed.
| null | null |
atoms4020014_perova
| 0 |
The response to these comments and changes to the manuscript in response to these comments is given below: 1.
| null | null |
The treatment involves quantum corrections which are treated by calculating the Wigner representation of the density matrix and I am not aware of the use of such an extensive use of Wigner representation to describe atom interferometry experiments.
| null | null |
atoms4020014_perova
| 0 |
1 Review Report 1 Originality/Novelty This paper treats an important question concerning the measurement of the gravitational constant G by atom interferometry.
| null | null |
The correction phi_Q was not discussed in the previous papers I know on the subject and I think that the paper must be published but, as explained below, important improvements are needed.
| null | null |
atoms4020014_perova
| 0 |
The response to these comments and changes to the manuscript in response to these comments is given below: 1.
| null | null |
The treatment involves quantum corrections which are treated by calculating the Wigner representation of the density matrix and I am not aware of the use of such an extensive use of Wigner representation to describe atom interferometry experiments.
| null | null |
atoms4020014_perova
| 0 |
Author response We would like to thank the referee for his/her careful reading of the manuscript and the helpful comments.
| null | null |
The results obtained seem reasonable, although I have no time to verify all the derivations.
| null | null |
atoms4020014_perova
| 0 |
Author response We would like to thank the referee for his/her careful reading of the manuscript and the helpful comments.
| null | null |
Review Report 2 In this manuscript, the influences of an external test mass on the phase of the signal of an atom interferometer are studied theoretically.
| null | null |
atoms4020014_perova
| 0 |
The response to these comments and changes to the manuscript in response to these comments is given below: 1.
| null | null |
These results are interesting to the people working in the field of atom interferometer, because the test mass are often used in the practical experiment.
| null | null |
atoms4020014_perova
| 0 |
The response to these comments and changes to the manuscript in response to these comments is given below: 1.
| null | null |
The response to these comments and changes to the manuscript in response to these comments is given below: 1.
| null | null |
atoms4020014_perova
| 0 |
Authors’ response We would like to thank the referee for his/her careful reading of the manuscript and the helpful comments.
| null | null |
The response to these comments and changes to the manuscript in response to these comments is given below: 1.
| null | null |
atoms4020014_perova
| 0 |
I recommend accepting this manuscript, provided the following points are clarified:
| null | null |
Review Report 2 In this manuscript, the influences of an external test mass on the phase of the signal of an atom interferometer are studied theoretically.
| null | null |
atoms4020014_perova
| 0 |
The response to these comments and changes to the manuscript in response to these comments is given below: 1.
| null | null |
The response to these comments and changes to the manuscript in response to these comments is given below: 1.
| null | null |
atoms4020014_perova
| 0 |
I recommend accepting this manuscript, provided the following points are clarified:
| null | null |
Review Report 2 In this manuscript, the influences of an external test mass on the phase of the signal of an atom interferometer are studied theoretically.
| null | null |
atoms4020014_perova
| 0 |
Author response We would like to thank the referee for his/her careful reading of the manuscript and the helpful comments.
| null | null |
The treatment involves quantum corrections which are treated by calculating the Wigner representation of the density matrix and I am not aware of the use of such an extensive use of Wigner representation to describe atom interferometry experiments.
| null | null |
atoms4020014_perova
| 0 |
How can the authors ascertain that mannose does not come from mannans in yeast extract?
| null | null |
The presented manuscript is related to the study of an exopolysaccharide isolated from the extremophilic microorganism Bacillus haynesii CamB6.
| null | null |
biom12060834_makarova
| 0 |
Figure 6: Bacterial EPSs are normally composed of repeating units.
| null | null |
They deleted erroneous information about mannose residues, but came up with new conclusions about mannose identity and linkages based solely on chemical shift of anomeric proton/carbon.
| null | null |
biom12060834_makarova
| 0 |
Also, β-glucopyranose and β-galactopyranose structures were identified and the acetylation was confirmed.
| null | null |
433, 434, 454, 458, and 507 : First section 3.6 (and its subsections) should be section 3.5.
| null | null |
biom12060834_makarova
| 0 |
528 and 531: “radical” Answer 36: Suggestion has been included in the revised version of the manuscript Comment 37: l. 535 and 536: “activity” Answer 37: Suggestion has been included in the revised version of the manuscript Comment 38: l. 537: No section 3.6.2 Answer 38:
| null | null |
Tick label values for glucose and yeast extract are different.
| null | null |
biom12060834_makarova
| 0 |
433, 434, 454, 458, and 507 : First section 3.6 (and its subsections) should be section 3.5.
| null | null |
How can the authors ascertain that mannose does not come from mannans in yeast extract?
| null | null |
biom12060834_makarova
| 0 |
Comment 19: l. 247: Volume of 0.2 mM ethanolic DPPH solution?
| null | null |
We will answer in the following paragraphs because all comments were related to the same topic.
| null | null |
biom12060834_makarova
| 0 |
Basically, the work was done at a fairly high professional level, the material is presented clearly, well structured, the data obtained are discussed with the previously obtained literature data.
| null | null |
Comment 19: l. 247: Volume of 0.2 mM ethanolic DPPH solution?
| null | null |
biom12060834_makarova
| 0 |
The evidences for the partial structure given are not convincing.
| null | null |
The presented manuscript is related to the study of an exopolysaccharide isolated from the extremophilic microorganism Bacillus haynesii CamB6.
| null | null |
biom12060834_makarova
| 0 |
In short, they allow to clearly identify the D-mannose α-(1→2) and α-(1→4) linkages in EPS.
| null | null |
These results suggest they are the prevailing units of the EPS backbone making it a branched one.
| null | null |
biom12060834_makarova
| 0 |
Sphingobactan, a new α-mannan exopolysaccharide from Arctic Sphingobacterium sp.
| null | null |
Based on the 1H NMR spectrum, the purity and/or heterogeneity of the EPS is questioned.
| null | null |
biom12060834_makarova
| 0 |
Comment 42: l. 683-684: Food-grade oils are not aliphatic and aromatic hydrocarbons.
| null | null |
The presented manuscript is related to the study of an exopolysaccharide isolated from the extremophilic microorganism Bacillus haynesii CamB6.
| null | null |
biom12060834_makarova
| 0 |
Comment 6: EPS vs. EPSs in plural form should be consistent throughout.
| null | null |
Based on the 1H NMR spectrum, the purity and/or heterogeneity of the EPS is questioned.
| null | null |
biom12060834_makarova
| 0 |
Casillo, A., Fabozzi, A., Russo Krauss, I., Parrilli, E., Biggs, C. I., Gibson, M. I., … Corsaro, M. M. (2021).
| null | null |
Chatterjee, S., Mukhopadhyay, S. K., Gauri, S. S., & Dey, S. (2018).
| null | null |
biom12060834_makarova
| 0 |
The studied EPS showed promising properties to use in the food industry.
| null | null |
528 and 531: “radical” Answer 36: Suggestion has been included in the revised version of the manuscript Comment 37: l. 535 and 536: “activity” Answer 37: Suggestion has been included in the revised version of the manuscript Comment 38: l. 537: No section 3.6.2 Answer 38:
| null | null |
biom12060834_makarova
| 0 |
Comment 17: l. 228: GPC defined on l. 231 (check) Answer 17:
| null | null |
(I was referring to the chemical method by methylation.)
| null | null |
biom12060834_makarova
| 0 |
They deleted erroneous information about mannose residues, but came up with new conclusions about mannose identity and linkages based solely on chemical shift of anomeric proton/carbon.
| null | null |
In combination with a high yield of polysaccharide from the bacterial mass, this makes it attractive for practical use.
| null | null |
biom12060834_makarova
| 0 |
The authors used the RSM based on central composite design technique to maximize the EPS production by B. haynesii, and also conducted a diverse study of the EPS properties.
| null | null |
Bacterial EPSs are normally composed of repeating units.
| null | null |
biom12060834_makarova
| 0 |
Author Response Thank you so much dear reviewer for your positive comments regarding the revised version of our manuscript.
| null | null |
481-482: “spectrum” Answer 33: Suggestion has been included in the revised version of the manuscript Comment 34: I.
| null | null |
biom12060834_makarova
| 0 |
However, there is no report that the mannan came from yeast extract (DOI: 10.1016/j.ijbiomac.2019.09.139, DOI: 10.1023/B:WIBI.0000033068.45655.2a).
| null | null |
IITKGP-BTPF3 capable of biological response modification.
| null | null |
biom12060834_makarova
| 0 |
According to the 1H NMR spectrum, it can be assumed that EPS has a complex branched structure.
| null | null |
According to Figure 7. the activity of the ascorbic acid is higher than the activity of EPS produced by CamB6.
| null | null |
biom12060834_makarova
| 0 |
Response 2: Dear reviewer, thanks for your valuable comments for improving the quality of this paper.
| null | null |
In addition, the yeast mannan have β-(1→4) linkage and the one found in this work have α-linkage type.
| null | null |
biom12060834_makarova
| 0 |
Probably, to establish its structure, it is necessary to use chemical methods (hydrolysis, methylation, etc.
| null | null |
→ Comment 1: The English language was improved, but there are still errors.
| null | null |
biom12060834_makarova
| 0 |
Comment 4: Acceptability for food applications was not discussed.
| null | null |
Units are not specified on the axes labels or in the legend.
| null | null |
biom12060834_makarova
| 0 |
In combination with a high yield of polysaccharide from the bacterial mass, this makes it attractive for practical use.
| null | null |
The new spectra emphasize this even more: for example, I count at least 10 H1/H2 cross peaks of different intensities on the COSY.)
| null | null |
biom12060834_makarova
| 0 |
→ Comment 2: The following comments were not addressed correctly: Why was linkage analysis not performed?
| null | null |
The information contained in the other 2D spectra was not exploited to provide structural information.
| null | null |
biom12060834_makarova
| 0 |
Manuscript biomolecules-1691308 In this manuscript, the exopolysaccharide from Bacillus haynesii CamB6 was exhaustively characterized.
| null | null |
Probably, to establish its structure, it is necessary to use chemical methods (hydrolysis, methylation, etc.
| null | null |
biom12060834_makarova
| 0 |
Units are not specified on the axes labels or in the legend.
| null | null |
Answer 1: To better understand EPS chemical structure, further 2D NMR experiments were performed and results are presented inside the manuscript.
| null | null |
biom12060834_makarova
| 0 |
IITKGP-BTPF3 capable of biological response modification.
| null | null |
(I was referring to peak intensities that are not uniform.
| null | null |
biom12060834_makarova
| 0 |
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