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Author Response We would like to thank the reviewer for their positive and critical review of our work.
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We feel that the manuscript has been significantly improved as a result of the suggested revisions.
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brainsci6010008_perova
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In table 3, the subheading “Peak X, Y, X” needs correction.
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However, in the latter case the authors need to address the issue of multiple correlations.
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brainsci6010008_perova
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However, in the latter case the authors need to address the issue of multiple correlations.
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Author Response We would like to thank the reviewer for their positive and critical review of our work.
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brainsci6010008_perova
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A reference for the determination that a dosage of antidepressants was “high” should be provided.
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We feel that the manuscript has been significantly improved as a result of the suggested revisions.
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brainsci6010008_perova
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This manuscript describes a cohort randomized crossover design comparing cutaneous heat pain ratings and brain activity during heat stimuli after conditions of quiet rest and cycling in patients with a physician-confirmed diagnosis of Fibromyalgia (FM) and age and sex matched controls.
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We feel that the manuscript has been significantly improved as a result of the suggested revisions.
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brainsci6010008_perova
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Elevations should be revised to higher so that readers do not erroneously believe that a pre-scan application of heat stimuli was administered.
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Elevations should be revised to higher so that readers do not erroneously believe that a pre-scan application of heat stimuli was administered.
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brainsci6010008_perova
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We have addressed each concern below and made changes in the manuscript accordingly.
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Considering discussion the results in relation to previous studies on exercise and neuroimaging.
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brainsci6010008_perova
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Author Response We would like to thank the reviewer for their positive and critical review of our work.
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This study has compared acute effects of exercise and inactivity in fibromyalgia (FM) and pain-free controls on changes in pain and cerebral activity in response to heat.
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brainsci6010008_perova
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The writing is clear, the analysis is sound, and the presentation is excellent with a few exceptions.
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How many were there that fit in this category?
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brainsci6010009_makarova
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How many were there that fit in this category?
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If so, how many and what would happen to the analysis if you removed them?
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brainsci6010009_makarova
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In table 1, the "-" is used to signify absent values but that should be footnoted in the table precisely what this signifies.
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The Odds ratios presented are dose dependent and, above 37.5 uG of Hg, they reach over 4.5 which are tremendous associations between an exposure and a disease outcome.
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brainsci6010009_makarova
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On page 11 line 4 you say levels of Hg in the environment and in humans are increasing but your reference #26 doesn't speak to that point.
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Are there better references to substantiate this point?
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brainsci6010009_makarova
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These results are relevant and important as thimerosal is still included in global vaccines although they have largely been removed from childhood vaccine in the United States.
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If so, how many and what would happen to the analysis if you removed them?
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brainsci6010009_makarova
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This is a straightforward analysis of an important database with profound implications for public health.
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This is an important study that deserves to be published.
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brainsci6010009_makarova
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If so, how many and what would happen to the analysis if you removed them?
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In table 1, the "-" is used to signify absent values but that should be footnoted in the table precisely what this signifies.
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brainsci6010009_perova
0
The writing is clear, the analysis is sound, and the presentation is excellent with a few exceptions.
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This is a straightforward analysis of an important database with profound implications for public health.
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brainsci6010009_perova
0
On page 11 line 4 you say levels of Hg in the environment and in humans are increasing but your reference #26 doesn't speak to that point.
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Can the authors address this point: is this database publicly available?
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brainsci6010009_perova
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In the exposed and control groups were there other related diseases such as Autism?
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On page 11 line 4 you say levels of Hg in the environment and in humans are increasing but your reference #26 doesn't speak to that point.
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brainsci6010009_perova
0
In table 1, the "-" is used to signify absent values but that should be footnoted in the table precisely what this signifies.
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If so, how many and what would happen to the analysis if you removed them?
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brainsci6010009_perova
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Can the authors address this point: is this database publicly available?
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The Odds ratios presented are dose dependent and, above 37.5 uG of Hg, they reach over 4.5 which are tremendous associations between an exposure and a disease outcome.
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brainsci6010009_perova
0
A better strategy would have been to predict each type of aggression while controlling its overlap with the other type (i.e., include reactive aggression when predicting proactive aggression and vice-versa).
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Given the severe limitations of their cross-sectional design, the authors need to revise their comments with respect to directionality and their use of causality terms throughout the manuscript.
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bs5040518_makarova
0
That is, no information is available in the present manuscript about alternative cluster solutions from the analysis, for example, the extent to which BIC and the silhouette coefficient differed for other solutions and so forth.
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Round 1: and Author Response The goal of this study was to distinguish subgroups of relationally aggressive females (i.e., reactively aggressive-only subgroup, reactively-and-proactively aggressive-combined subgroup, non-aggressive subgroup), on the basis of nine factors reflecting individual characteristics, peer-related variables and R3 parental control.
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bs5040518_makarova
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Second, the manuscript should be carefully edited as there are a fair number of grammatical and typographical errors, including lack of subject-verb agreement in places (e.g., using “were” and “was” in the same sentence, both referring to the same measure - CU traits), omitted words, and so forth.
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This work, as with other recent work, makes clear that the most severely aggressive youth tend to engage in high R2 levels of both proactive and reactive aggression and are otherwise also generally more distressed and dysregulated, as compared with youth who are more moderately aggressive and tend to engage in reactive aggression only, and youth who have low levels of aggression.
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bs5040518_makarova
0
Below are a few comments that could hopefully help improve a solid piece of work.
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Given the severe limitations of their cross-sectional design, the authors need to revise their comments with respect to directionality and their use of causality terms throughout the manuscript.
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bs5040518_makarova
0
For example, how to explain that the combined group is not more delinquent than the reactively aggressive group although they report more CU traits and more delinquent peers, two known factors in regard to delinquent behaviors?
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Given the severe limitations of their cross-sectional design, the authors need to revise their comments with respect to directionality and their use of causality terms throughout the manuscript.
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bs5040518_makarova
0
Given the severe limitations of their cross-sectional design, the authors need to revise their comments with respect to directionality and their use of causality terms throughout the manuscript.
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In my view, this manuscript will make a nice contribution to the literature.
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bs5040518_makarova
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In my view, this manuscript will make a nice contribution to the literature.
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First, it is recommended that the authors provide more information about the selection of the cluster solution.
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bs5040518_makarova
0
Round 1: and Author Response The goal of this study was to distinguish subgroups of relationally aggressive females (i.e., reactively aggressive-only subgroup, reactively-and-proactively aggressive-combined subgroup, non-aggressive subgroup), on the basis of nine factors reflecting individual characteristics, peer-related variables and R3 parental control.
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Second, the authors do not mention why they implicitly selected an additive model (i.e., each factor makes a unique and independent contribution) instead of, for example, an interactional model.
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bs5040518_makarova
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In my view, this manuscript will make a nice contribution to the literature.
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In particular, and contrary to what the authors seem to believe, it is not possible to know whether differences between the two aggressive groups reflect differences in levels of relational aggression or in type of relational aggression (reactive only vs. combined), given that the combined group is obviously much more aggressive than the reactive-only group.
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bs5040518_makarova
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Creating groups based on a cluster analysis may have created unnecessary problems.
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Second, the authors do not mention why they implicitly selected an additive model (i.e., each factor makes a unique and independent contribution) instead of, for example, an interactional model.
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bs5040518_makarova
0
Below are a few comments that could hopefully help improve a solid piece of work.
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Second, the manuscript should be carefully edited as there are a fair number of grammatical and typographical errors, including lack of subject-verb agreement in places (e.g., using “were” and “was” in the same sentence, both referring to the same measure - CU traits), omitted words, and so forth.
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bs5040518_makarova
0
Some measures such as self-reports of peers’ delinquency are also flawed because of a possible projection bias.
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For example, how to explain that the combined group is not more delinquent than the reactively aggressive group although they report more CU traits and more delinquent peers, two known factors in regard to delinquent behaviors?
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bs5040518_perova
0
For example, how to explain that the combined group is not more delinquent than the reactively aggressive group although they report more CU traits and more delinquent peers, two known factors in regard to delinquent behaviors?
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Round 1: Author Response to Reviewer 3 First, some factors (i.e., CU traits) may be predictors whereas others (i.e., delinquency) may be correlates or consequences of relational aggression.
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bs5040518_perova
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There are a number of grammatical and lexical problems throughout the manuscript that need to be taken care of.
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This work, as with other recent work, makes clear that the most severely aggressive youth tend to engage in high R2 levels of both proactive and reactive aggression and are otherwise also generally more distressed and dysregulated, as compared with youth who are more moderately aggressive and tend to engage in reactive aggression only, and youth who have low levels of aggression.
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bs5040518_perova
0
First, it is recommended that the authors provide more information about the selection of the cluster solution.
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There are two areas to address to strengthen the paper a bit more.
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bs5040518_perova
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There are two areas to address to strengthen the paper a bit more.
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The study is strengthened by the person-centered approach to data analysis, by the large sample, by focusing on girls who have been much less studied than boys, and by the clear rationale for the study.
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bs5040518_perova
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These findings are in contrast to earlier work, which assumed that proactive and reactive aggression represented distinct typologies.
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Round 1: and Author Response Interesting paper!!
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bs5040518_perova
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Second, the authors do not mention why they implicitly selected an additive model (i.e., each factor makes a unique and independent contribution) instead of, for example, an interactional model.
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That is, no information is available in the present manuscript about alternative cluster solutions from the analysis, for example, the extent to which BIC and the silhouette coefficient differed for other solutions and so forth.
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bs5040518_perova
0
A better strategy would have been to predict each type of aggression while controlling its overlap with the other type (i.e., include reactive aggression when predicting proactive aggression and vice-versa).
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The study is consistent with other recently published work in this area in identifying subgroups that are characterized by their severity of aggression.
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bs5040518_perova
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Round 1: and Author Response Interesting paper!!
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Round 1: and Author Response Interesting paper!!
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bs5040518_perova
0
Round 1: and Author Response Interesting paper!!
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Overall, this is a nice paper that looks to make a contribution.
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bs5040518_perova
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There are two areas to address to strengthen the paper a bit more.
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Below are a few comments that could hopefully help improve a solid piece of work.
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bs5040518_perova
0
Below are a few comments that could hopefully help improve a solid piece of work.
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Despite the use of a relatively large sample and of sound measures, this study falls short of making an important contribution to the current literature for several reasons.
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bs5040518_perova
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However, my main concern with the study is that there were too many analyses presented to interpret in a meaningful way.
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Participants completed two waves of data collection approximately 1-year apart.
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bs6010004_makarova
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Participants completed two waves of data collection approximately 1-year apart.
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On p. 4 the first sentence of second full paragraph, “Regarding sexual subjectivity and its link to greater sexual exploration and experience, one cross-sectional with a sample of females” is missing the word “study.” The authors could provide more theoretical explanation of why there might be gender differences in sexual subjectivity.
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bs6010004_makarova
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There is an increase in Type I error with the multiple t-tests conducted thatshould be addressed.
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Also, a more thorough description of the measurement of the construct and the validity of the measurement could be described in that section.
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bs6010004_makarova
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Participants completed two waves of data collection approximately 1-year apart.
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**We also expanded the first paragraph of the Limitations to say: Although this study provided insight into how aspects of sexual subjectivity differed over one year in young men and women and uncovered associations of age and sexual behavior with sexual subjectivity, there were two limitations worthy of note.
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bs6010004_makarova
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Finally, on a selfish note, I wrote an extensive review piece on this topic (Harden, 2014, "A Sex-Positive Framework for Reseach on Adolescent Sexuality" in Perspectives on Psychological Science), and I would, of course, be happy if the authors included a reference to my paper in their Introduction or Discussion.
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**We did not keep an exact count of the number of students approached about the study, but we estimate that we approached about 375 students.
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bs6010004_makarova
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Although an exact count was not available, we estimate that 375 students were approached to participate, resulting in a participation rate of approximately 79%.
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Using a longitudinal design with two assessments, we investigated patterns of entitlement to sexual partner pleasure and self-efficacy to achieve sexual pleasure among 295 young men and women aged 17-25 years attending one Australian university.
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bs6010004_makarova
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That seems to be the model implied by the analyses, but it is never explicitly specified.
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** We added a comment that data were collected at one Australian university to the abstract, and added a summary statement and note about limitations related to generalizability.
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bs6010004_makarova
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We also tested whether entitlement and efficacy differed by gender, and hypothesized that entitlement and efficacy would be higher in older participants and those with more sexual experience.
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Finally, on a selfish note, I wrote an extensive review piece on this topic (Harden, 2014, "A Sex-Positive Framework for Reseach on Adolescent Sexuality" in Perspectives on Psychological Science), and I would, of course, be happy if the authors included a reference to my paper in their Introduction or Discussion.
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bs6010004_makarova
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Important limitations of the study including that this was a study of students at one university only should be included in the Abstract.
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At T1, 225 of the participants (76%) reported a history of sexual intercourse and 9% reported having had no sexual experience apart from kissing.
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bs6010004_makarova
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Moreover there is a comment in the Methods that 80% of the subjects reported being only attracted to members of the same sex.
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Why would behavior that has already happened contribute to a re-ordering of individuals over the course of the next year?
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bs6010004_makarova
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Some more specific suggestions are provided below.
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From the relatively high percentage of non-heterosexual participants, there seems to be some selection bias.
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bs6010004_makarova
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A low response rate will seriously limit the validity of the findings and this should be discussed as an important limitation also.
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Moreover there is a comment in the Methods that 80% of the subjects reported being only attracted to members of the same sex.
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bs6010004_makarova
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There might be some interesting data collected in the present study.
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Using a longitudinal design with two assessments, we investigated patterns of entitlement to sexual partner pleasure and self-efficacy to achieve sexual pleasure among 295 young men and women aged 17-25 years attending one Australian university.
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bs6010004_makarova
0
This contradiction underscores my concern about attrition (point #1); I wonder if the seeming decrease from Time 1 to Time 2 is an artifact of attrition.
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The authors should revise the paper providing more theoretical background and accompanying analyses.
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bs6010004_makarova
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The reporting of group differences in the participants section might be better placed in the results section after the measures are described.
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With better theoretical framing and a more limited set of analyses, the value of the study results should be more clear.
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bs6010004_makarova
0
However, my main concern with the study is that there were too many analyses presented to interpret in a meaningful way.
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We also tested whether entitlement and efficacy differed by gender, and hypothesized that entitlement and efficacy would be higher in older participants and those with more sexual experience.
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bs6010004_makarova
0
There is also the possibility that individuals more interested in sex and relationships chose to participate.
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Predictions about how the specific subscales of the inventory might relate to age and experience might be provided to make the results more meaningful (see the comment about theory relating to analyses discussed above).
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bs6010004_makarova
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That is, any one who did not complete both assessments was not included in the analyses.
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What were participants told about the purpose of the study?
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bs6010004_makarova
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A sense of entitlement to sexual partner pleasure increased significantly over the year of the study, whereas, on average, there was no change in self-efficacy over time.
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Author Response There might be some interesting data collected in the present study.
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bs6010004_perova
0
Similarly, there are many correlation tests performed which increases Type I error that needs to be addressed.
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This contradiction underscores my concern about attrition (point #1); I wonder if the seeming decrease from Time 1 to Time 2 is an artifact of attrition.
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bs6010004_perova
0
The combining of the male and female versions of the sexual subjectivity inventories should be described in more detail, and the validity of creating the subscales should be explained.
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Third, although longitudinal data can be a quite powerful tool for understanding change and development, the current analyses squander some of that power.
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bs6010004_perova
0
This seems to contrast with later statements and would also seem to be an unlikely finding.
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Perhaps factor analysis could be used to determine appropriate subscales?
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bs6010004_perova
0
Overall, 91% were white/Caucasian, 3% were Asian, 1 was Aboriginal/Pacific Islander, and the remaining participants indicated an "Other" sociocultural background.
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The reporting of group differences in the participants section might be better placed in the results section after the measures are described.
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bs6010004_perova
0
The authors should revise the paper providing more theoretical background and accompanying analyses.
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The abstract now reads: Abstract: Many scholars have called for an increased focus on positive aspects of sexual health and sexuality.
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bs6010004_perova
0
At the very least, the Discussion should consider how generalizable these results are.
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Although an exact count was not available, we estimate that 375 students were approached to participate, resulting in a participation rate of approximately 79%.
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bs6010004_perova
0
Please note - we have also shortened the title, found some other typographical errors to fix, and fixed some references.
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A sense of entitlement to sexual partner pleasure increased significantly over the year of the study, whereas, on average, there was no change in self-efficacy over time.
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bs6010004_perova
0
**We did not keep an exact count of the number of students approached about the study, but we estimate that we approached about 375 students.
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That seems to be the model implied by the analyses, but it is never explicitly specified.
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bs6010004_perova
0
Therefore, in order to capture sexual subjectivity as it emerges and develops most rapidly along with sexual behavior, future studies may need to begin with a younger population.
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Please note - we have also shortened the title, found some other typographical errors to fix, and fixed some references.
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bs6010004_perova
0
The abstract now reads: Abstract: Many scholars have called for an increased focus on positive aspects of sexual health and sexuality.
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Fifth, one set of results seems quite contradictory: sense of entitlement to sexual self-pleasure decreased, on average, from Time 1 to Time 2, but sense of entitlement to sexual self-pleasure was positively correlated with age.
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bs6010004_perova
0
Most lived with their parents (61%) and reported being only attracted to the other sex (80%).
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The abstract now reads: Abstract: Many scholars have called for an increased focus on positive aspects of sexual health and sexuality.
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bs6010004_perova
0
There was no evidence that any association differed between young men and young women.
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What percentage of people who were approached agreed to participate?
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bs6010004_perova
0
The authors should revise the paper providing more theoretical background and accompanying analyses.
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Perhaps factor analysis could be used to determine appropriate subscales?
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bs6010004_perova
0
Some more specific suggestions are provided below.
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Age was positively associated with T1 entitlement, and experience with a wider range of partnered sexual behaviors was concurrently associated with more entitlement and efficacy and was also associated with increased entitlement to partner pleasure and increased self-efficacy in achieving sexual pleasure at T2 relative to T1.
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bs6010004_perova
0
Third, although longitudinal data can be a quite powerful tool for understanding change and development, the current analyses squander some of that power.
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Similarly, there are many correlation tests performed which increases Type I error that needs to be addressed.
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bs6010004_perova
0
It seems that a more interesting and direct test of the longitudinal effects of sexual behavior on sexual subjectivity would test whether new sexual behaviors (that is, sexual behaviors experienced between Time 1 and Time 2) predict change in sexual subjectivity from Time 1 to Time 2.
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The reporting of group differences in the participants section might be better placed in the results section after the measures are described.
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bs6010004_perova
0
International Journal of Environmental Research and Public Health.
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Response 9: The supplemental Information (i.e., office temperature, number of employees) are added in the revised version.
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buildings12040417_makarova
0
Yin, J., Zhua, S., MacNaughton, P., Joseph, G., Allen, J.G., Spengler, J.D., 2018.
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1, Figure 1 should be improved regarding the arrow.
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buildings12040417_makarova
0
Response 17: Spearman’s correlation test was conducted, and the revised contents are shown in the updated version.
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Point 2: The illustrations in the article are small and a bit vague, some pictures can shrink a little, not to the top to the border, these can be optimized.
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buildings12040417_makarova
0
Mollazadeh, M., Zhu, YM., Application of Virtual Environments for Biophilic Design: A Critical Review.
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The questionnaire results reveal that the employees from the understudy companies hold a relatively positive opinion on wellbeing, nature-relatedness, indoor environmental quality, and biophilic design for their health promotion.
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buildings12040417_makarova
0
Response 9: The supplemental Information (i.e., office temperature, number of employees) are added in the revised version.
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In terms of the reviewer think that the listed attributes span across different domains and the communal features are not that apparent, we believe it is due to the research perspective of biophilic design is different from the perspectives of building science and traditional POE studies (please find the detailed explanations in the respond for Comment #9).
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buildings12040417_makarova
0
Response to Reviewer 3 Comments (Round 2) Buildings-1613867.
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Concerning the self-related evaluation scales GH and NR, the score range of GH and HR are minimum 4 to maximum 20, and the obtained results illustrate moderately high opinions, the values of 15.00 (2.00) and 14.00 (3.00) for GH and NR.
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buildings12040417_makarova
0
After reviewing their revised manuscript, I felt that their responses were on-point and addressed my earlier thoughts.
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Prospect and refuge Prospect: long views of surrounding settings Refuge: sites of safety and security 20.
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buildings12040417_makarova
0
Similarly, the Green Mark system uses the green plot ratio, assigning credits to greenery provision to enhance biodiversity and visual relief.
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The detailed description of the demographic information is in Section 3.1.
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buildings12040417_makarova
0
Practical methodologies to establish biophilic design frameworks for specific workplace typology.
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Response to Reviewer 2 Comments Point 1: The study about the evaluation of biophilic attributes in the workplace for improving health and wellbeing is actual and interesting and therefore the paper is fulfilling the scientific criteria to be published.
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buildings12040417_makarova
0
Complexity & Order adheres to a spatial hierarchy that similar to those encountered in nature 11.
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Light Glass walls and clerestories, reflecting colors and materials 2.
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buildings12040417_makarova
0
Transitional spaces hallways, thresholds, doorways, gateways, and areas that link the indoors and outdoors especially porches, patios, courtyards, colonnades 23.
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Revision in Page 3 Line 109: “It has helped experts to obtain user’s feedbacks over the last five decades [31,32].” Point 6:
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buildings12040417_makarova
0
A data-driven analysis of occupant workspace dissatisfaction.
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There are general biophilic design frameworks (e.g., the 24 Biophilic Design Attributes and the 14 Patterns of Biophilic Design) and green building, healthy building standards (e.g., WELL v2 and Singapore Green Mark) that include biophilia into the certification systems in nowadays.
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buildings12040417_makarova
0
Practical methodologies to establish biophilic design frameworks for specific workplace typology.
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Although I appreciated the thoroughness to which the descriptive statistical was explained, I wasn’t convinced the mean was the best indicator for the data, considering that evaluation scores were collected on a 5-point scale and not a continuous linear one.
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buildings12040417_makarova
0
An image showing the indoor conditions and outdoor façade for each might be beneficial.
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Response 9: The supplemental Information (i.e., office temperature, number of employees) are added in the revised version.
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buildings12040417_makarova
0
And the corresponding figures (Figure 1 in Page 13 Line 359-361 and Figure 4 in Page 16-17 of the original manuscript) are removed in the revised version.
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There were two very minor points that I came across, which they may want to reconsider before proceeding with their article.
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buildings12040417_makarova
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Studies proofed that biophilic design benefits workers’ health and productivity in an office environment [60, 61, 62, 63].” Citations are added in the Reference list: 59.
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Risk/Peril An identifiable able threat coupled with a reliable safeguard.
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buildings12040417_makarova
0
Complexity & Order adheres to a spatial hierarchy that similar to those encountered in nature 11.
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c) Furthermore, the questionnaire results enhance our knowledge on the practical ap-plication of biophilic design frameworks for the workplace and contributed to more framework design consideration.
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buildings12040417_makarova
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First, to simplify the image, we put all the definitions into a new table in the appendix (Appendix A. Definitions of biophilic design attributes and patterns).
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For instance, in most cases, the employers would not create an office environment that makes the workers feel “Prospect”, “Refuge”, “Mystery”, and “Risk”.
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buildings12040417_makarova
0
Revision in Page 13 Line 381-394: The Cronbach’s α coefficient value of the main scale is 0.72, while those of the subscales GH, NR, and BDE in order are obtained as 0.68, 0.79, and 0.63, indicating that the questionnaire is reliable (i.e., an acceptable reliability: Cronbach's α>0.6) [57, 58] (Table 8).
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And the corresponding figures (Figure 1 in Page 13 Line 359-361 and Figure 4 in Page 16-17 of the original manuscript) are removed in the revised version.
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buildings12040417_makarova
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The investigation explains that combined literature review and POE results are one of the practical methodologies to establish biophilic design frameworks for specific workplace typology.
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Additionally, the effectiveness of such design in practical design projects for user wellbeing still requires confirmation.
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buildings12040417_makarova
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Physiological and cognitive performance of exposure to biophilic indoor environment.
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The same parameters (e.g., daylight, thermal comfort, and air-quality, office layout and building form) can be classified in different classifications (i.e., the traditional POE frameworks and the biophilic design frameworks) by different perspectives.
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buildings12040417_makarova
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The Cronbach’s Alpha with an Alpha>0.6 considered acceptable internal consistency in this study.
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Yin, J., Zhua, S., MacNaughton, P., Joseph, G., Allen, J.G., Spengler, J.D., 2018.
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buildings12040417_makarova
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