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|---|---|---|---|
these cells are shown to be thioguanine resistant , to be unable to incorporate exogenously added hypoxanthine into purine nucleotides , to complement our other adenine-specific purine auxotrophs , ade-h and ade-i but not to complement a cell isolated by virtue of thioguanine resistance , and to lack the activity of hgprt . | NA | {
"id": "C0034140",
"name": "purine",
"pos": [
116,
122
]
} | {
"id": "C0039902",
"name": "thioguanine",
"pos": [
265,
276
]
} |
a higher heat resistance of loosely-attached microsomal esterases as compared with that of free esterases of the rat 's pancreas is due to a higher proportion of heat resistant slow carboxylesterases in the former . | NA | {
"id": "C0014894",
"name": "esterases",
"pos": [
56,
65
]
} | {
"id": "C0007067",
"name": "carboxylesterases",
"pos": [
182,
199
]
} |
this technique will minimize seeding of the tumor , provide a more complete eradication of the neoplasm without loss of the eye , and hopefully , assure either a cure or a longer interval free of local recurrences or metastasis than is presently attainable . | NA | {
"id": "C0027645",
"name": "seeding",
"pos": [
29,
36
]
} | {
"id": "C0027627",
"name": "metastasis",
"pos": [
217,
227
]
} |
little doses of the poison increased the incorporation of 14c-hydrolysate of chlorella protein into proteins of liver cells and the high doses inhibited this process . | NA | {
"id": "C0033631",
"name": "hydrolysate",
"pos": [
62,
73
]
} | {
"id": "C0033684",
"name": "proteins",
"pos": [
100,
108
]
} |
on the basis of activating effectiveness on c-aat the catecholamines were arranged in decreasing order as follows : adrenaline , isadrine , noradrenaline . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
116,
126
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
140,
153
]
} |
glycosaminoglycans of tegmental cartilage of human caput femoris were separated into the fractions , which were identified as keratosulfate , hyaluronic acid , heparitin sulphate , chondroitin-4-sulphate , chondroitin-6-sulphate , dermatan sulphate and heparin . | NA | {
"id": "C0017973",
"name": "glycosaminoglycans",
"pos": [
0,
18
]
} | {
"id": "C0019143",
"name": "heparitin sulphate",
"pos": [
160,
178
]
} |
glycosaminoglycans of tegmental cartilage of human caput femoris were separated into the fractions , which were identified as keratosulfate , hyaluronic acid , heparitin sulphate , chondroitin-4-sulphate , chondroitin-6-sulphate , dermatan sulphate and heparin . | NA | {
"id": "C0017973",
"name": "glycosaminoglycans",
"pos": [
0,
18
]
} | {
"id": "C0019134",
"name": "heparin",
"pos": [
253,
260
]
} |
a prolonged ( within 4 days ) administration of hydrocortisone or protamin-zn-insulin into preadolescent male rats with body weight of 70-90 g caused a distinct increase in the synthesis of dna-like rna , precursor of ribosomal rna in nuclei and ribosomal rna in cytoplasma of liver tissue . | NA | {
"id": "C0035668",
"name": "rna",
"pos": [
199,
202
]
} | {
"id": "C0035701",
"name": "ribosomal rna",
"pos": [
246,
259
]
} |
the data obtained suggest that dna-like rna , precursor of ribosomal rna from nuclei and ribosomal rna from cytoplasma of liver tissue of preadolescent male rats participate in the synthesis of transaminases in liver tissue . | NA | {
"id": "C0035668",
"name": "rna",
"pos": [
40,
43
]
} | {
"id": "C0035701",
"name": "ribosomal rna",
"pos": [
89,
102
]
} |
the signigicant role of androgenes was assumed to consist in carring out the inducing effect of glucocorticoids and insulin , which influenced to a variable degree the synthesis of dna-like rna , of ribosomal rna precursors from nuclei and of ribosomal rna from liver tissue cytoplasma in preadolescent and adult animals . | NA | {
"id": "C0035668",
"name": "rna",
"pos": [
190,
193
]
} | {
"id": "C0035701",
"name": "ribosomal rna",
"pos": [
243,
256
]
} |
the fall of three important gluconeogenic amino acids alanine , glycine , proline , and that of three branched chain amino acids was particularly striking . | NA | {
"id": "C0002520",
"name": "amino acids",
"pos": [
42,
53
]
} | {
"id": "C0001898",
"name": "alanine",
"pos": [
54,
61
]
} |
the fall of three important gluconeogenic amino acids alanine , glycine , proline , and that of three branched chain amino acids was particularly striking . | NA | {
"id": "C0002520",
"name": "amino acids",
"pos": [
42,
53
]
} | {
"id": "C0017890",
"name": "glycine",
"pos": [
64,
71
]
} |
the fall of three important gluconeogenic amino acids alanine , glycine , proline , and that of three branched chain amino acids was particularly striking . | NA | {
"id": "C0002520",
"name": "amino acids",
"pos": [
42,
53
]
} | {
"id": "C0002521",
"name": "branched chain amino",
"pos": [
102,
122
]
} |
the importance of thymus on the degree of increased blood pressure and vascular disease in mice with doca and salt hypertension . | NA | {
"id": "C0042373",
"name": "vascular",
"pos": [
71,
79
]
} | {
"id": "C0020538",
"name": "hypertension",
"pos": [
115,
127
]
} |
the appraisement of mineral waters microbial quality is closely depending of their definition : waters endowed with therapeutic properties , strongly mineralised waters , etc . | NA | {
"id": "C0026157",
"name": "mineral waters",
"pos": [
20,
34
]
} | {
"id": "C0043047",
"name": "waters",
"pos": [
162,
168
]
} |
[ considerations on critics towards conditioned waters ( drinking water in general and particularly mineral water ) especially from the microbiological point of view ] . | NA | {
"id": "C0043047",
"name": "waters",
"pos": [
48,
54
]
} | {
"id": "C0599638",
"name": "drinking water",
"pos": [
57,
71
]
} |
[ considerations on critics towards conditioned waters ( drinking water in general and particularly mineral water ) especially from the microbiological point of view ] . | NA | {
"id": "C0043047",
"name": "waters",
"pos": [
48,
54
]
} | {
"id": "C0026157",
"name": "mineral water",
"pos": [
100,
113
]
} |
this examination leads to eliminate those reproaches because the consumer knows to which he is exposed , being forewarned : -when he is using mineral water at the cure-resort , by the thermal consultant who is watching over him , -when he is using one or the other of the conditioned waters , -either by the medical practictioner , who should give him the contre-indicates ; | NA | {
"id": "C0026157",
"name": "mineral water",
"pos": [
142,
155
]
} | {
"id": "C0043047",
"name": "waters",
"pos": [
284,
290
]
} |
the compact nuclei of the macrogametocytes had inconspicuous dna but prominent nucleoli whereas those of the microgametocytes were irregular and showed a central aggregate of dna . | NA | {
"id": "C0012854",
"name": "dna",
"pos": [
61,
64
]
} | {
"id": "C0000702",
"name": "a",
"pos": [
177,
178
]
} |
although the two patients had different types of aphasia ( one broca 's aphasia and the other wernicke 's aphasia ) , the degree of the language impairment initially manifested in english and japanese was almost equivalent in each case with the pattern of impairment corresponding to the respective types of aphasia . | NA | {
"id": "C1510456",
"name": "wernicke 's aphasia",
"pos": [
94,
113
]
} | {
"id": "C0003537",
"name": "aphasia",
"pos": [
308,
315
]
} |
estimation of rates of kinine formation by different kininogenasses from highly purified hmwk and lmwk preparations showed that those kininogens are functionally different substrates , since blood plasma kallikreines release kinines from hmwk at a greater rates , whereas tissue kallikreines , e. g. human saliva kallikreine release kinines from lmwk . | NA | {
"id": "C0022713",
"name": "kininogens",
"pos": [
134,
144
]
} | {
"id": "C0019536",
"name": "hmwk",
"pos": [
238,
242
]
} |
estimation of rates of kinine formation by different kininogenasses from highly purified hmwk and lmwk preparations showed that those kininogens are functionally different substrates , since blood plasma kallikreines release kinines from hmwk at a greater rates , whereas tissue kallikreines , e. g. human saliva kallikreine release kinines from lmwk . | NA | {
"id": "C0022713",
"name": "kininogens",
"pos": [
134,
144
]
} | {
"id": "C0023922",
"name": "lmwk",
"pos": [
346,
350
]
} |
electric stimulation ( ec ) of a suspension of native synaptic membranes of rat brain cortex in the krebs-ringer-glucose medium revealed ca-dependent inhibition of na+ , k+-atpase and inhibition of transport ca-activated , mg-dependent atpase . | NA | {
"id": "C0001473",
"name": "atpase",
"pos": [
173,
179
]
} | {
"id": "C0001477",
"name": "ca",
"pos": [
208,
210
]
} |
the biochemical literature indicated that older animals show differences in response to alcohol using metabolic measures such as : alcohol dehydrogenase , blood alcohol concentration , and acetaldehyde . | NA | {
"id": "C0001962",
"name": "alcohol",
"pos": [
88,
95
]
} | {
"id": "C0684262",
"name": "blood alcohol concentration",
"pos": [
155,
182
]
} |
an investigation of the thrombocytes adhesion after hellem ( 1960 ) showed that `` '' in vitro '' '' tests norepinephrine , epinephrine , histamine , serotonin and adenosine-diphosphate , when used in doses of 100-25,0 gamma/ml , were capable of raising the thrombocytes adhesion , while heparin administered in doses of 0.5-0.05 u/ml depressed and in a dose of 0.025 u/ml mildly activated this capacity of the thrombocytes . | NA | {
"id": "C0028351",
"name": "s norepinephri",
"pos": [
105,
119
]
} | {
"id": "C0014563",
"name": ", epinephri",
"pos": [
122,
133
]
} |
diflorasone diacetate , a new topical corticosteroid , was generally more potent than three high potency reference standards ( fluocinonide , beta-methasone 17-valerate and fluocinolone acetonide ) when the compounds were dissolved in 95 % alcohol and applied in vasoconstrictor assays in healthy volunteers . | NA | {
"id": "C0016299",
"name": "fluocinonide",
"pos": [
127,
139
]
} | {
"id": "C0016298",
"name": "fluocinolone acetonide",
"pos": [
173,
195
]
} |
removal of adherent cells or complement-mediated killing of rabbit thymus lymphocyte antigen ( btla ) bearing rabbit t lymphocytes did not abolish the responsiveness ( increased thymidine incorporation ) of lymphoid cells to antibody against immunoglobulin allotype , nocardia water-soluble mitogen ( nwsm ) , pneumococcal polysaccharide siii ( ppsiii ) , s. abortus lipopolysaccharide ( lps ) , lipid a conjugated to bovine serum albumin and a crude preparation containing c polysaccharide from the cell wall of diplococcus pneumoniae . | NA | {
"id": "C0003241",
"name": "antibody",
"pos": [
225,
233
]
} | {
"id": "C0021006",
"name": "immunoglobulin allotype",
"pos": [
242,
265
]
} |
removal of adherent cells or complement-mediated killing of rabbit thymus lymphocyte antigen ( btla ) bearing rabbit t lymphocytes did not abolish the responsiveness ( increased thymidine incorporation ) of lymphoid cells to antibody against immunoglobulin allotype , nocardia water-soluble mitogen ( nwsm ) , pneumococcal polysaccharide siii ( ppsiii ) , s. abortus lipopolysaccharide ( lps ) , lipid a conjugated to bovine serum albumin and a crude preparation containing c polysaccharide from the cell wall of diplococcus pneumoniae . | NA | {
"id": "C0023810",
"name": "lipopolysaccharide",
"pos": [
367,
385
]
} | {
"id": "C0023767",
"name": "lipid a",
"pos": [
396,
403
]
} |
( 2 ) cba/j amyloid spleen cell suspensions appear to be enriched with antibody dependent killer cells and precursors of antibody-forming cells ; | NA | {
"id": "C0007634",
"name": "cell",
"pos": [
27,
31
]
} | {
"id": "C0018956",
"name": "precursors",
"pos": [
107,
117
]
} |
in the first trimester of that pregnancy she wanted to interrupt pregnancy and an alleged artificial abortus was performed . | NA | {
"id": "C0032979",
"name": "first",
"pos": [
7,
12
]
} | {
"id": "C0032961",
"name": "pregnancy",
"pos": [
65,
74
]
} |
fifty to 85 % of the total nucleocapsid population remained 'nucleated ' or full in terms of the nucleic acid core making them useful as a source of dna . | NA | {
"id": "C0028606",
"name": "nucleic acid",
"pos": [
97,
109
]
} | {
"id": "C0012854",
"name": "dna",
"pos": [
149,
152
]
} |
the sera exhausted of precipitins still agglutinate the bacteria , thus confirming the assumption that agglutinins and precipitins may be different antibodies . | NA | {
"id": "C0032936",
"name": "precipitins",
"pos": [
22,
33
]
} | {
"id": "C0003241",
"name": "antibodies",
"pos": [
148,
158
]
} |
the protective antibodies could be completely absorbed from both antisera by heat killed bacteria and released afterwards . | NA | {
"id": "C0003241",
"name": "antibodies",
"pos": [
15,
25
]
} | {
"id": "C0020960",
"name": "antisera",
"pos": [
65,
73
]
} |
the diagnosis of primary hyperparathyroidism was established in 24 patients ( in 19 histologically confirmed ) so that the incidence of primary hyperparathyroidism ( 1,05 % ) compares favorably with that reported from some foreign authors . | NA | {
"id": "C0020502",
"name": "hyperparathyroidism",
"pos": [
25,
44
]
} | {
"id": "C0221002",
"name": "primary hyperparathyroidism",
"pos": [
136,
163
]
} |
the dynamics of dying and the subsequent recovery of the main vital functions such as cardiac performance , respiration and unconditioned reflexes were investigated in 24 dogs resuscitated by bryukhonenko 's method of artificial circulation after 13-15 min clinical death caused by asphyxia . | NA | {
"id": "C0011065",
"name": "death",
"pos": [
266,
271
]
} | {
"id": "C0004044",
"name": "asphyxia",
"pos": [
282,
290
]
} |
we concluded that successful resuscitation after clinical death caused by asphyxia was possible only when the blood flow was 1.2-1.5 times higher than the normal cardiac output . | NA | {
"id": "C0011065",
"name": "death",
"pos": [
58,
63
]
} | {
"id": "C0004044",
"name": "asphyxia",
"pos": [
74,
82
]
} |
human fibroblasts containing a translocation between the x chromosome and chromosome 15 were fused with the 6-thioguanine-resistant mouse cell line , ir . | NA | {
"id": "C0016030",
"name": "fibroblasts",
"pos": [
6,
17
]
} | {
"id": "C0007634",
"name": "cell",
"pos": [
138,
142
]
} |
somatic cell hybrids between thymidine kinase-deficient mouse cells and human fibroblasts carrying a translocation of the distal third of the long arm of chromosome 10 to chromosome 17 were studied for the expression of cytoplasmic glutamic-oxaloacetic transaminase . | NA | {
"id": "C0007634",
"name": "cells",
"pos": [
62,
67
]
} | {
"id": "C0016030",
"name": "fibroblasts",
"pos": [
78,
89
]
} |
effects of lead ion on brain microsomes : inhibition of cation transport atpase and stimulation of phosphorylation . | NA | {
"id": "C0022023",
"name": "ion",
"pos": [
16,
19
]
} | {
"id": "C0007447",
"name": "cation",
"pos": [
56,
62
]
} |
comparison of the amount of vldl triglyceride fatty acids ( 0.04 micromoles/min/litter ) and of maternal plasma free fatty acids ( 0.08 micronmoles/min/litter ) transferred into the fetus indicates that the maternal plasma triglycerides are a source of fetal fatty acids , that can not be neglected . | NA | {
"id": "C0015688",
"name": "free fatty acids",
"pos": [
112,
128
]
} | {
"id": "C0015684",
"name": "fatty acids",
"pos": [
259,
270
]
} |
experiments conducted on a total of 34 guinea pigs showed a considerable decrease in the response of smooth bronchial muscles to novodrine , adrenaline , and noradrenaline subsequent to bcg and ovalbumin sensitization of experimental animals . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
141,
151
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
158,
171
]
} |
in normal guinea pigs , minimal relaxation of smooth tracheal muscles was brought about by 7.10 ( -8 ) - 1.10 ( -7 ) g/ml novodrine , 1.10 ( -7 ) - 9.10 ( -7 ) g/ml adrenaline , and 1.10 ( -6 ) - 8.10 ( -6 ) g/ml noradrenaline . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
165,
175
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
213,
226
]
} |
free sterols , sterol esters , triglycerides , phospholipids were major components of cercarial lipids , triglycerides , wax esters , free fatty acids , squalen were major components of skin surface lipids . | NA | {
"id": "C0043076",
"name": "wax",
"pos": [
121,
124
]
} | {
"id": "C0023779",
"name": "lipids",
"pos": [
199,
205
]
} |
the authors have analyzed the 5 fluoro cytosine ( 5fc ) activity on strains of candida albicans and criptococcus neoformans , both in vitro and in vivo . | NA | {
"id": "C0010843",
"name": "cytosine",
"pos": [
39,
47
]
} | {
"id": "C0016278",
"name": "5fc",
"pos": [
50,
53
]
} |
[ in-vitro microbiological evaluation of the action of gentamicin and sisomicin o schizomycetes of the salmonella genus ] . | NA | {
"id": "C0017436",
"name": "gentamicin",
"pos": [
55,
65
]
} | {
"id": "C0037209",
"name": "sisomicin",
"pos": [
70,
79
]
} |
the in vitro activity of gentamicin and sisomicin towards 142 clinical isolated salmonella strains was determined and statisically evaluated . | NA | {
"id": "C0017436",
"name": "gentamicin",
"pos": [
25,
35
]
} | {
"id": "C0037209",
"name": "sisomicin",
"pos": [
40,
49
]
} |
among the clotting factors , platelet factor 3 and factor xiii were found to be inhibited by the gold preparation . | NA | {
"id": "C0005789",
"name": "clotting factors",
"pos": [
10,
26
]
} | {
"id": "C0032182",
"name": "platelet",
"pos": [
29,
37
]
} |
among the clotting factors , platelet factor 3 and factor xiii were found to be inhibited by the gold preparation . | NA | {
"id": "C0005789",
"name": "clotting factors",
"pos": [
10,
26
]
} | {
"id": "C0015528",
"name": "factor xiii",
"pos": [
51,
62
]
} |
the presence of a certain amount of hcg in urine of women is the basis for a number of pregnancy tests and its content is diagnostic in evaluation of foeto-placental health during pregnancy , indicative of safe normal pregnancy , multiple pregnancies , threatened abortions and many other trophoblastic diseases such as hydatidiform mole and ectopic pregnancy . | NA | {
"id": "C2931618",
"name": "trophoblastic diseases",
"pos": [
289,
311
]
} | {
"id": "C0020217",
"name": "hydatidiform mole",
"pos": [
320,
337
]
} |
diagnostic problems of acute pancreatitis , relapsing pancreatitis , and chronic pancreatitis are discussed taking into account the author 's own results . | NA | {
"id": "C0030305",
"name": "pancreatitis",
"pos": [
29,
41
]
} | {
"id": "C0149521",
"name": "chronic pancreatitis",
"pos": [
73,
93
]
} |
it is concluded , that repeated tests of pancreatitis function and demonstration of pancreatic calcification are more important for establishing the diagnosis of chronic pancreatitis than studies of pancreatic morphology including endoscopic retrograde pancreatography ( erp ) . | NA | {
"id": "C0030305",
"name": "pancreatitis",
"pos": [
41,
53
]
} | {
"id": "C0149521",
"name": "chronic pancreatitis",
"pos": [
162,
182
]
} |
a total of 42 multi-resistant urinary pathogens , sensitive to gentamycin only , were investigated with regard to the effects of dicloxacillin and ampicillin or cloxacillin/flucloxacillin and amoxycillin in combination . | NA | {
"id": "C0012093",
"name": "dicloxacillin",
"pos": [
129,
142
]
} | {
"id": "C0009077",
"name": "cloxacillin",
"pos": [
176,
187
]
} |
a total of 42 multi-resistant urinary pathogens , sensitive to gentamycin only , were investigated with regard to the effects of dicloxacillin and ampicillin or cloxacillin/flucloxacillin and amoxycillin in combination . | NA | {
"id": "C0002680",
"name": "ampicillin",
"pos": [
147,
157
]
} | {
"id": "C0002645",
"name": "amoxycillin",
"pos": [
192,
203
]
} |
a total of 42 multi-resistant urinary pathogens , sensitive to gentamycin only , were investigated with regard to the effects of dicloxacillin and ampicillin or cloxacillin/flucloxacillin and amoxycillin in combination . | NA | {
"id": "C0009077",
"name": "cloxacillin",
"pos": [
131,
142
]
} | {
"id": "C0016267",
"name": "flucloxacillin",
"pos": [
173,
187
]
} |
the fatty acid profiles obtained showed small quantitative change with different sugars , sucrose concentrations and types of growth . | NA | {
"id": "C0242209",
"name": "sugars",
"pos": [
81,
87
]
} | {
"id": "C0038636",
"name": "sucrose",
"pos": [
90,
97
]
} |
inhibition of dopa decarboxylation by ro 4-4602 within the whole body abolished the effect of l-dopa , while lower dosages of ro 4-4602 , which do not penetrate the blood-brain barrier , had less effect . | NA | {
"id": "C0013023",
"name": "dopa",
"pos": [
14,
18
]
} | {
"id": "C0023570",
"name": "l-dopa",
"pos": [
94,
100
]
} |
( 1 ) a tropical marine butterflyfish , chaetodon ornatissimus , had oil-filled bones ( 66-80 % lipid , percent dry weight ) hence may be a suitable condidate . | NA | {
"id": "C0028908",
"name": "oil",
"pos": [
69,
72
]
} | {
"id": "C0023779",
"name": "lipid",
"pos": [
96,
101
]
} |
( 2 ) the tropical marine fishes exallias brevis , pomacentrus jenkensi , and chromus agilis , and a canadian fish sebastes ruberrimus , had intermediate quantities of oil in their bones ( 12-49 % lipid ) . | NA | {
"id": "C0028908",
"name": "oil",
"pos": [
168,
171
]
} | {
"id": "C0023779",
"name": "lipid",
"pos": [
197,
202
]
} |
the technique of elution by pronase of murine lymph node cells adherent to relevant allogeneic target cells has been developed for enrichment of effectory t cell population . | NA | {
"id": "C0007634",
"name": "cells",
"pos": [
57,
62
]
} | {
"id": "C3485979",
"name": "allogeneic",
"pos": [
84,
94
]
} |
[ liquor-cytological methods for the demonstration of tumor cells in clinical diagnosis and therapy control in neoplastic processes ] . | NA | {
"id": "C0027651",
"name": "tumor",
"pos": [
54,
59
]
} | {
"id": "C0027671",
"name": "neoplastic processes",
"pos": [
111,
131
]
} |
[ determination of lipid and lipoprotein kinetics by means of the intravenous lipid tolerance test in patients with portacaval shunt ] . | NA | {
"id": "C0023820",
"name": "lipoprotein",
"pos": [
29,
40
]
} | {
"id": "C0023779",
"name": "lipid",
"pos": [
78,
83
]
} |
this is why we investigate , on the rabbit , the issues of chronic administration of glycerides by rectal route , on caloric balance and on a biochemical view to seek for in lipid composition of tissues the print of lipids administrated by transanal way . | NA | {
"id": "C0017860",
"name": "glycerides",
"pos": [
85,
95
]
} | {
"id": "C0023779",
"name": "lipids",
"pos": [
216,
222
]
} |
the coli-rectal administration of saturated glycerides produces at middle end only qualitative variations of lipids extracts . | NA | {
"id": "C0017860",
"name": "glycerides",
"pos": [
44,
54
]
} | {
"id": "C0023779",
"name": "lipids",
"pos": [
109,
115
]
} |
when sodium oxalate and sodium citrate were simultaneously added to the diet , citrate was shown to have no effect on digestibility , biological value , the coefficient of nutritive utilization and the coefficient of body retention , but did , however , considerably increase the amount of utilized calciun which was diverted towards milk . | NA | {
"id": "C0142825",
"name": "sodium citrate",
"pos": [
24,
38
]
} | {
"id": "C0008857",
"name": "citrate",
"pos": [
79,
86
]
} |
virological and clinical researches have been done on hospitalized newborn infants ' with various infectious diseases ( respiratory infections , aseptic meningitis , serious generalized disease ) . | NA | {
"id": "C0009450",
"name": "infectious diseases",
"pos": [
98,
117
]
} | {
"id": "C0035243",
"name": "respiratory infections",
"pos": [
120,
142
]
} |
under study were the diurnal biological rhythms in 37 young mature male wistar rats and in 44 young mature female wistar rats in the cells of the granulation tissue ( fibroblasts ) 4 and 9 days respectively after injuring the liver . | NA | {
"id": "C0007634",
"name": "cells",
"pos": [
133,
138
]
} | {
"id": "C0016030",
"name": "fibroblasts",
"pos": [
167,
178
]
} |
reaction of the capacitance vessels of the abdominal cavity and the pelvis was studied in dogs with the cardiotoxic myocardial necrosis complicated by the cardiogenic shock . | NA | {
"id": "C0027051",
"name": "myocardial necrosis",
"pos": [
116,
135
]
} | {
"id": "C0036980",
"name": "cardiogenic shock",
"pos": [
155,
172
]
} |
one fraction representing the fraction of high-molecular proteins was absent in membrane proteins of the visual analyser in the dark-reared animals ; | NA | {
"id": "C0033684",
"name": "proteins",
"pos": [
57,
65
]
} | {
"id": "C0025252",
"name": "membrane proteins",
"pos": [
80,
97
]
} |
the samples of polysome rrna were disc-electrophoresed , and the specific activity of the 28s-rna was determined . | NA | {
"id": "C0035701",
"name": "rrna",
"pos": [
24,
28
]
} | {
"id": "C0035705",
"name": "28s-rna",
"pos": [
90,
97
]
} |
in spite of the decreased rna-synthetic response of the 21-trisomic lymphocytes ( determined earlier ) the specific activity of the rrna in the aberrant cells failed to differ from the normal . | NA | {
"id": "C0035668",
"name": "rna",
"pos": [
26,
29
]
} | {
"id": "C0035701",
"name": "rrna",
"pos": [
132,
136
]
} |
cell-associated herpesvirus related to marek 's disease ( md ) was isolated from the direct culture of kidney cells of naturally infected chickens at taoyuan or by inoculation of clinical specimens to chick kidney ( ck ) and chick embryo fibroblast cells . | NA | {
"id": "C0007634",
"name": "cell",
"pos": [
0,
4
]
} | {
"id": "C0016030",
"name": "fibroblast cells",
"pos": [
238,
254
]
} |
the effects of dyphylline [ 7- ( 2,3-dihydroxypropyl ) theophylline ] on the toxicity of hycanthone on the frog 's heart . | NA | {
"id": "C0013360",
"name": "dyphylline",
"pos": [
15,
25
]
} | {
"id": "C0039771",
"name": "theophylline",
"pos": [
55,
67
]
} |
[ quantitative study on the `` '' in-vitro '' '' trichomonicide effect of tinidazole ( beta-1-ethyl-sulfonyl-ethyl 2 methyl-5-nitroimidazole ) on recently isolated strains of trichomonas vaginalis ] . | NA | {
"id": "C0040263",
"name": "f tinidazo",
"pos": [
72,
82
]
} | {
"id": "C0028179",
"name": "5-nitroimidazo",
"pos": [
124,
138
]
} |
homozygous cases for hemoglobin j mexico ( alpha54 ( e3 ) gln replaced by glu ) evidence for a duplicated alpha gene with unequal expression . | NA | {
"id": "C0017797",
"name": "gln",
"pos": [
58,
61
]
} | {
"id": "C0061472",
"name": "glu",
"pos": [
74,
77
]
} |
the amino acid substitution in a new hemoglobin variant , hb baylor ( alpha2beta281 ( ef5 ) leu replaced by arg ) , has been determined by application of column chromatography and amino acid analysis of the tryptic peptides . | NA | {
"id": "C0019016",
"name": "a",
"pos": [
4,
5
]
} | {
"id": "C0019046",
"name": "hb",
"pos": [
58,
60
]
} |
the propositus in a black family has elevated hb-f and approximately equal amounts of hb-a and hb-s . | NA | {
"id": "C0015936",
"name": "hb-f",
"pos": [
46,
50
]
} | {
"id": "C0019046",
"name": "hb",
"pos": [
95,
97
]
} |
the effects of sodium chloride , sodium acetate , benzoic acid , sodium benzoate , malonic acid , and sodium malonate on growth and aflatoxin production by aspergillus flavus were investigated in synthetic media . | NA | {
"id": "C0053225",
"name": "benzoic acid",
"pos": [
50,
62
]
} | {
"id": "C0142805",
"name": "sodium benzoate",
"pos": [
65,
80
]
} |
benzoic acid ( ph 3.9 ) and sodium benzoate ( ph 5.0 ) at 0.4 g/100 ml completely inhibited growth and aflatoxin production . | NA | {
"id": "C0053225",
"name": "benzoic acid",
"pos": [
0,
12
]
} | {
"id": "C0142805",
"name": "sodium",
"pos": [
28,
34
]
} |
the inhibitory action of benzoic acid and sodium benzoate appeared to be a function of undissociated benzoic acid molecules . | NA | {
"id": "C0142805",
"name": "sodium benzoate",
"pos": [
42,
57
]
} | {
"id": "C0053225",
"name": "benzoic acid",
"pos": [
101,
113
]
} |
the rats were fed the basal diet or basal diet plus 12 , 24 , 36 and 48 mg iron/kg diet provided as ferrous sulfate or ferric orthophosphate . | NA | {
"id": "C0302583",
"name": "iron",
"pos": [
75,
79
]
} | {
"id": "C0060282",
"name": "ferrous sulfate",
"pos": [
100,
115
]
} |
iron-deficient rats were rehabilitated with diets supplying iron from white wheat bread , bread ash or ferrous sulfate as a standard . | NA | {
"id": "C0302583",
"name": "iron",
"pos": [
0,
4
]
} | {
"id": "C0060282",
"name": "ferrous sulfate",
"pos": [
103,
118
]
} |
the effectiveness of artificial circulation by the method of bryukhonenko and his colleagues in the resuscitation of dogs that had died from drowning in fresh- or salt-water was studied . | NA | {
"id": "C0011065",
"name": "died",
"pos": [
131,
135
]
} | {
"id": "C0013142",
"name": "drowning",
"pos": [
141,
149
]
} |
[ comparative studies on the problem of nephrotoxicity of the aminoglycosides : kanamycin , amikacin , butirosin and kanendomycin ] . | NA | {
"id": "C0022487",
"name": "kanamycin",
"pos": [
80,
89
]
} | {
"id": "C0002499",
"name": "amikacin",
"pos": [
92,
100
]
} |
[ comparative examinations of serum-glycoside concentrations in glycoside intoxications with extracardiac adverse effects after intake of beta-methyldigoxin , beta-acetyldigoxin and digoxin ] . | NA | {
"id": "C0025132",
"name": "beta-methyldigoxin",
"pos": [
138,
156
]
} | {
"id": "C0012265",
"name": "digoxin",
"pos": [
182,
189
]
} |
the activity of the different enzymes are under the dependence of the genetic equipment of the plant , of the nitrogen and oligo-element nutrition and of the different factors acting on the photosynthesis . | NA | {
"id": "C0028158",
"name": "nitrogen",
"pos": [
110,
118
]
} | {
"id": "C0013879",
"name": "element",
"pos": [
129,
136
]
} |
the cytoplasmic poly ( a ) -containing rna or messenger rna appears to represent a subset of approximately 10-20 % of the information in the nuclear poly ( a ) -rna . | NA | {
"id": "C0035696",
"name": "messenger rna",
"pos": [
46,
59
]
} | {
"id": "C0035668",
"name": "rna",
"pos": [
161,
164
]
} |
the b 19 brucellosis strain has been widely used in the production of live vaccine against bovine brucellosis in the field for the last 30 years . | NA | {
"id": "C0006309",
"name": "brucellosis",
"pos": [
9,
20
]
} | {
"id": "C0302363",
"name": "bovine brucellosis",
"pos": [
91,
109
]
} |
the elevated accumulation of 35so4 by i-cell , hunter and maroteaux-lamy fibroblasts was decreased by the addition of ( + ) -- cyanidanol to the culture medium , but the degradation of previously labeled , intracellular glycosaminoglycans was not . | NA | {
"id": "C0007634",
"name": "cell",
"pos": [
40,
44
]
} | {
"id": "C0016030",
"name": "fibroblasts",
"pos": [
73,
84
]
} |
electrical stimulation is a valuable diagnostic method to reveal the focality , the multiplicity and the degree of the seizure disposition in epilepsy . | NA | {
"id": "C0036572",
"name": "seizure",
"pos": [
119,
126
]
} | {
"id": "C0014544",
"name": "epilepsy",
"pos": [
142,
150
]
} |
in a study of 135 cases , the authors present the dermatologic lesions occasioned by onchocercosis , study and discuss the value of the following three diagnostic procedures : the skin snip technic , the mazzotti test , and indirect fluorescent antibody test as used in a region of africa where onchocercosis is , with dipetalonemosis , the principal filariasis . | NA | {
"id": "C0029001",
"name": "onchocercosis",
"pos": [
85,
98
]
} | {
"id": "C0016085",
"name": "filariasis",
"pos": [
351,
361
]
} |
in a study of 135 cases , the authors present the dermatologic lesions occasioned by onchocercosis , study and discuss the value of the following three diagnostic procedures : the skin snip technic , the mazzotti test , and indirect fluorescent antibody test as used in a region of africa where onchocercosis is , with dipetalonemosis , the principal filariasis . | NA | {
"id": "C0012517",
"name": "dipetalonemosis",
"pos": [
319,
334
]
} | {
"id": "C0016085",
"name": "filariasis",
"pos": [
351,
361
]
} |
more older children were accepting placement than were younger children , and the majority of the parents did not contemplate the child 's return home , being quite satisfied with placement in the institution . | NA | {
"id": "C1455726",
"name": "older children",
"pos": [
5,
19
]
} | {
"id": "C0008059",
"name": "child 's",
"pos": [
130,
138
]
} |
in the adrenal gland of gottingen miniature pigs adrenaline- and noradrenaline-storing cells showed follicular and reticular arrangements , which were not observed in the domesticated form ( german land race ) of sus scrofa . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
49,
59
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
65,
78
]
} |
light and electron microscopic study of spontaneous prolactin cell adenomas , found at autopsy of 26 aging female long-evans rats and of 9 aging male wistar rats , revealed pigment particles in the cytoplasm of some adenoma cells . | NA | {
"id": "C0033375",
"name": "prolactin cell adenomas",
"pos": [
52,
75
]
} | {
"id": "C0001430",
"name": "adenoma",
"pos": [
216,
223
]
} |
analyses revealed that the prevalence rate of myocardial infarction , angina pectoris , pathologic q-wave , and st depressions in connection with exercise , were significantly higher among the surviving cotwins whose partners had died from ihd than those whose partners had died from other causes . | NA | {
"id": "C0027051",
"name": "myocardial infarction",
"pos": [
46,
67
]
} | {
"id": "C0151744",
"name": "ihd",
"pos": [
240,
243
]
} |
interstitial bilateral pregnancy appears to be by far the rarest kind of tubal twin pregnancy , apparently only one case having been reported in the literature , and this referring to a nonsimultaneous pregnancy . | NA | {
"id": "C1401136",
"name": "interstitial",
"pos": [
0,
12
]
} | {
"id": "C0032994",
"name": "tubal",
"pos": [
73,
78
]
} |
the disposition of adrenaline and noradrenaline storing cells in the adrenal medulla has been studied in the rat . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
19,
29
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
34,
47
]
} |
comparisons of synthetic 1-18 acth ( organon 2001 ) and 1-39 acth of animal origin in human subjects . | NA | {
"id": "C0010192",
"name": "synthetic",
"pos": [
15,
24
]
} | {
"id": "C0001655",
"name": "1-39 acth",
"pos": [
56,
65
]
} |
further work has revealed that fgf promotes the growth of several other mesoderm-derived cell types including adrenal cells , chondrocytes , myoblasts , vascular smooth muscle cells , and vascular endothelial cells . | NA | {
"id": "C0225369",
"name": "chondrocytes",
"pos": [
126,
138
]
} | {
"id": "C0007634",
"name": "cells",
"pos": [
209,
214
]
} |
human fibroblasts are the only cells that regularly produce cytomegalovirus of adapted laboratory strains and release fair amounts of cell free virus . | NA | {
"id": "C0016030",
"name": "fibroblasts",
"pos": [
6,
17
]
} | {
"id": "C0007634",
"name": "cells",
"pos": [
31,
36
]
} |
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