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these findings suggest that the fast effect of thyrotropin occurs at the translational level to provide for acute adjustments in thyroglobulin production by regulating the rate of translation of existing mrna . | process_includes_biological_process | {
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} | {
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[ changes in the external respiration and hemodynamics during the inhalation of increasing concentrations of carbon dioxide by the rebreathing method ] . | process_includes_biological_process | {
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} | {
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"name": "inhalation",
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} |
subcellular fractions from porcine corpora lutea of the reproductive cycle and pregnancy were shown to have specific binding sites for ovine prolactin ( oprl ) . | process_includes_biological_process | {
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} | {
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specifically , a therapists expressed greater avowed approval of in-therapy discussion of unusual thought and behavior , subjective material such as dreams and fears , and certain nontraditional attitudes toward divorce and feminine roles . | process_includes_biological_process | {
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} | {
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by means of trend-calculations it was further established that in the autopsy material of the department the number of the sudden natural death of women in the reproductive age during the 25 years remained on the same level , but the number of death cases connected with gestation decreased . | process_includes_biological_process | {
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} | {
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continuation of thythmic respiration after destruction of a number of inspiratory neurons and/or fibers in the midline or one side of the medulla indicates that all the inspiratory neurons and fibers are not essential for the maintenance of respiration . | process_includes_biological_process | {
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} | {
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cessation of thythmic respiration after destruction of all or most of inspiratory neurons on both sides of the midline indicates the essential role of the medulla-oblongata for genesis or maintenance of rhythmic respiration . | process_includes_biological_process | {
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the basic ventilation values - tidal volume ( vt ) , breathing frequency ( f ) , minute ventilation ( ve ) and the duration of inspiration ( ti ) and expiration ( te ) -- were determined in adult male rats . | process_includes_biological_process | {
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the basic ventilation values - tidal volume ( vt ) , breathing frequency ( f ) , minute ventilation ( ve ) and the duration of inspiration ( ti ) and expiration ( te ) -- were determined in adult male rats . | process_includes_biological_process | {
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} | {
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moreover , we will attempt to obtain a greater degree of rapprochement and cross-fertilization between the dynamic and behavioral schools of thought . | process_includes_biological_process | {
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these findings are consistent with the hypothesis that the expression of the endogenous rat apoa-i gene in l6e9 cells is prevented by hypermethylation , suggesting that compared to other mechanisms which control initiation of transcription , dna methylation may play a higher hierarchical role in the regulation of expression of eukaryotic genes . | process_includes_biological_process | {
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mdr has been strongly linked to the overexpression of a membrane-associated glycoprotein , p-glycoprotein , which appears to play a role in drug efflux . | process_includes_biological_process | {
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} | {
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it is suggested that in wilms ' tumorigenesis , imprinting normally renders inactive a transforming gene on the maternally derived chromosome 11 , leaving intact the paternally inherited chromosome 11 and the wilms ' transforming gene that it carries . | process_includes_biological_process | {
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} | {
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this finding suggests that transcription initiated in the 5 ' flanking region does proceed past the polyadenylation site . | process_includes_biological_process | {
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} | {
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} |
the synthesis of 250-330 nucleotide run-off transcripts and 4-9 nucleotide sarkosyl-resistant transcription intermediates requires atp both for rna synthesis and for activation of the system prior to rna synthesis . | process_includes_biological_process | {
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} | {
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the synthesis of 250-330 nucleotide run-off transcripts and 4-9 nucleotide sarkosyl-resistant transcription intermediates requires atp both for rna synthesis and for activation of the system prior to rna synthesis . | process_includes_biological_process | {
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} | {
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thus we argue that atp activates the transcription system in a step prior to rna synthesis . | process_includes_biological_process | {
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} | {
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immediately after treatment , patients were asked to respond to a list of 25 dentist behaviors thought to be associated with positive dentist-patient interaction . | process_includes_biological_process | {
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} | {
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} |
while the beta 1 tubulin gene is constitutively expressed during development , beta 3 mrna is restricted to two distinct phases : mid embryogenesis and metamorphosis . | process_includes_biological_process | {
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} | {
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tgf-beta mrna increases in the regenerating liver and reaches a peak ( about 8 times higher than basal levels ) after the major wave of hepatocyte cell division and mitosis have taken place and after the peak expression of the ras protooncogenes . | process_includes_biological_process | {
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} | {
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there was a significant reduction in both inspiratory and expiratory times in the animals breathing nitrous oxide and an increase in the negative pressures developed in the obstructed airway during inspiration . | process_includes_biological_process | {
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} | {
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} |
in addition to these biological measurements of gene expression in progenitor cells , significant levels of neo-specific rna , similar to the levels of rna expression in the virus-producing fibroblast cell line , were detected in the bone marrow cells after preselection . | process_includes_biological_process | {
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} | {
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} |
1,25- ( oh ) 2d3 has two effects on calbindin mrna formation : first , to permit the expression of the calbindin gene and a second effect , of slower onset but more persistent , which increases either the rate of calbindin gene transcription or the stability of calbindin mrna . | process_includes_biological_process | {
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although ifn-alpha 2 and tpa exhibited additive effects on sigm expression , they had opposing effects on cell proliferation , cell cycle progression , and induction of 2-5a synthetase activity , suggesting that these agents down-regulate sigm expression through independent pathways . | process_includes_biological_process | {
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} | {
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these results indicate that cell-mediated immunity to parasite-related ag as reflected in lymphocyte responses in vitro is diminished in infected individuals , and that this may be caused by defects in t cell activation . | process_includes_biological_process | {
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} | {
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manipulations of relative goal value ( learning vs. performance ) and perceived ability ( high vs. low ) resulted in the predicted differences on measures of task choice , performance during difficulty , and spontaneous verbalizations during difficulty . | process_includes_biological_process | {
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} | {
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} |
our chronic suppression of awareness of emotional arousal together with loss of the ritualized support of affiliative behavior may result in repressed emotional responses which find somatic expression in diseases such as essential hypertension . | process_includes_biological_process | {
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} | {
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the lengths of the products of in vitro transcription , from dna templates which possess the transcription start regions of each of the early genes , were determined and compared to the lengths of dna products generated by s1 nuclease protection and primer extension , in order to demonstrate that the 5 ' termini identified by s1 mapping and primer extension are due to transcription initiation and not to mrna processing . | process_includes_biological_process | {
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} | {
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since run off transcription with isolated nuclei represents essentially elongation of the initiated transcripts , the data obtained can be interpreted on the basis that heme regulates cytochrome p-450 gene transcription elongation . | process_includes_biological_process | {
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} | {
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} |
translational control in early sea urchin embryogenesis : initiation factor eif4f stimulates protein synthesis in lysates from unfertilized eggs of strongylocentrotus purpuratus . | process_includes_biological_process | {
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} | {
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in addition , the metastable phase behavior of all of the non-hydroxy fatty acid species was found to be more complex than previously thought , with several phases of high transition temperatures and enthalpies possible . | process_includes_biological_process | {
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} | {
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} |
these results implicate the role of transcription activation in tpa-induced odc gene expression and indicate that retinoic acid may inhibit tpa-induced odc gene transcription . | process_includes_biological_process | {
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} | {
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} |
chiasma frequencies have been collected from males of 33 species of marsupial , varying widely with respect to size , reproduction and development . | process_includes_biological_process | {
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} | {
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} |
this drug inhibited transcription of rdna by blocking initiation of transcription , whereas it had no effect on the elongation of the rrna transcript . | process_includes_biological_process | {
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} | {
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} |
since novobiocin has been shown to inhibit rna polymerases ii- and iii-directed transcription of linear dnas by interfering with a step ( s ) in the initiation reaction , these data suggest that initiation of transcription of all classes of rna is inhibited by novobiocin by a mechanism independent of its effect on dna topoisomerase ii . | process_includes_biological_process | {
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} | {
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the authors have previously reported mild improvement of behavior and cognition in a group of 17 nondepressed patients with dementia of the alzheimer type ( dat ) treated with two doses of l-deprenyl ( 10 and 40 mg/day ) . | process_includes_biological_process | {
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} | {
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} |
these results show that lymphocytes from aged mice exhibit defects in gene expression very early in the activation process and suggest that these deficits may involve , at least for some genes , alterations in post-transcriptional processing . | process_includes_biological_process | {
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} | {
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} |
these results suggest that tnf-induced cytotoxicity is linked to cell cycle-associated processes and that tnf is capable of overriding the normal cellular controls that coordinately link the dna replicative cycle with the mitotic cycle . | process_includes_biological_process | {
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} | {
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} |
the chemical nature of mucin or the histogenesis of tumor should not be determined simply by depending on certain features of mucin granule , because these mucin granules might be influenced by the direction of cell differentiation , the maturity of mucin granule , and the abnormalities in its development . | process_includes_biological_process | {
"id": "C0178679",
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} | {
"id": "C0007589",
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211,
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} |
the expression of the lta4-hydrolase gene but not the 5-lipoxygenase gene was demonstrated on the transcriptional level in northern blots and on the translational level by western blots . | process_includes_biological_process | {
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"name": "expression",
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14
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} | {
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} |
the expression of the lta4-hydrolase gene but not the 5-lipoxygenase gene was demonstrated on the transcriptional level in northern blots and on the translational level by western blots . | process_includes_biological_process | {
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"name": "expression",
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} | {
"id": "C1519614",
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} |
the effect on reproduction and fetal growth of a protein-deficient diet administration during pregnancy was studied in young and adult rats . | process_includes_biological_process | {
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} | {
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} |
cells selected for resistance to doxorubicin ( dox ) express the multidrug resistance ( mdr ) phenotype , and resistance has been suggested to be due primarily to enhanced cellular efflux of drug . | process_includes_biological_process | {
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} | {
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} |
systemic lupus erythematosus in an autoimmune disease of unknown etiology , which is seen more frequently in women than in men , especially in the reproductive age range , and which when associated with pregnancy may be lethal if the diagnosis is not made opportunely or treatment is inadequate . | process_includes_biological_process | {
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} | {
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} |
in frogs hypophysectomy causes cell proliferation in lens epithelium to subside entirely , with better than 95 % of the cells arresting in g1 . | process_includes_biological_process | {
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} | {
"id": "C1517342",
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} |
to elucidate the mechanism of attenuating the ammonia-induced tachypnea , the present study examined the discharge patterns and rates of slowly adapting pulmonary stretch receptors ( sars ) and rapidly adapting pulmonary stretch receptors ( rars ) in relation to the change in respiration produced by ammonia inhalation in anesthetized , spontaneously breathing rabbits . | process_includes_biological_process | {
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} | {
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} |
the transcription product has an upstream non-coding sequence of 70 nucleotides preceding an open reading frame of 1776 bases and a 3 ' untranslated region in which two alternative polyadenylation sites have been found . | process_includes_biological_process | {
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} | {
"id": "C0949765",
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} |
specifically , we have seen that mid-globular embryos can be arrested irreversibly in their development when heat-shocked , whereas all other stages of embryogenesis , both before and after this stage , are fully capable of normal development after the stress . | process_includes_biological_process | {
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} | {
"id": "C0013936",
"name": "embryogenesis",
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} |
our studies indicate that the beta-conglycinin family evolved by both duplication and insertion/deletion events , and that beta-conglycinin gene expression is regulated at both the transcriptional and posttranscriptional levels . | process_includes_biological_process | {
"id": "C0017262",
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140,
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} | {
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} |
although it has been shown that ionizing radiation can cause neoplastic cell transformation directly , that high-let heavy ions in general can be more effective than photons in transforming cells , and that the radiogenic cell transformation is a multi-step process [ correction of processes ] , we know very little about the molecular nature of lesions important for cell transformation , the relationship between lethal and transformational damages , and the evolution of initial damages into final chromosomal aberrations which alter the growth control of cells . | process_includes_biological_process | {
"id": "C0007621",
"name": "neoplastic cell transformation",
"pos": [
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} | {
"id": "C1510411",
"name": "transformational",
"pos": [
426,
442
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} |
the reproductive parameters used to measure fertility were mean days to first service on all cows and mean days open , first service conception rates and services per pregnancy on cows that became pregnant . | process_includes_biological_process | {
"id": "C0035150",
"name": "reproductive",
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} | {
"id": "C0009637",
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133,
143
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} |
the reproductive parameters used to measure fertility were mean days to first service on all cows and mean days open , first service conception rates and services per pregnancy on cows that became pregnant . | process_includes_biological_process | {
"id": "C0035150",
"name": "reproductive",
"pos": [
4,
16
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} | {
"id": "C0032961",
"name": "pregnancy",
"pos": [
167,
176
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} |
in an experiment to examine the relationships between adrenals and reproductive cycle , 10 mg dexamethasone ( a synthetic glucocorticoid ) were injected intramuscularly twice daily for 10 d to four black bengal goats , beginning on day 11 of the synchronized estrous cycle . | process_includes_biological_process | {
"id": "C0035150",
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} | {
"id": "C0025329",
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272
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} |
these results indicate that , in one patient with alzheimer 's disease , different rna species coding for the ? amyloid peptide precursor arise by alternative splicing of a single transcriptional unit , and use different polyadenylation sites . | process_includes_biological_process | {
"id": "C0040649",
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180,
195
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} | {
"id": "C0949765",
"name": "polyadenylation",
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221,
236
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} |
[ studies on respiratory function during the developmental age . ii . values of maximum expiratory volume per second ( mevs ) in subjects involved in physical training activities ] . | process_includes_biological_process | {
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} | {
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88,
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} |
the results were related to wyckoff 's theory of observing behavior and to the notions of uncertainty , reduction , and lack of information as extensions of the concepts of reinforcement and motivation . | process_includes_biological_process | {
"id": "C0004927",
"name": "behavior",
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} | {
"id": "C0026605",
"name": "motivation",
"pos": [
191,
201
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} |
while such cells had been suspected from earlier studies of normal immune responses , the development of monoclonal b cell models using tumor cells has provided a means to readily detect these suppressor t cells and to investigate the mechanisms by which they mediate their effects . | process_includes_biological_process | {
"id": "C0301872",
"name": "immune responses",
"pos": [
67,
83
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} | {
"id": "C1511002",
"name": "development",
"pos": [
90,
101
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} |
previous attempts to use tumor energy metabolism as a target for antineoplastic therapy have used single agents aimed at inhibiting either glycolysis or oxidative phosphorylation . | process_includes_biological_process | {
"id": "C0014272",
"name": "energy metabolism",
"pos": [
31,
48
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} | {
"id": "C0017952",
"name": "glycolysis",
"pos": [
139,
149
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} |
just under 1.6 million abortions were performed , about three percent of women of reproductive age obtained an abortion , and about 30 percent of pregnancies ( excluding those ending in stillbirths and miscarriages ) were terminated by abortion . | process_includes_biological_process | {
"id": "C0035150",
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82,
94
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} | {
"id": "C0032961",
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146,
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} |
we also present data on expression of the cbh2 gene and show that the transcription start points of the cbh2 gene are heterogeneous and are located 32 to 52 bp downstream from a putative tata box . | process_includes_biological_process | {
"id": "C0017262",
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]
} | {
"id": "C0040649",
"name": "transcription",
"pos": [
70,
83
]
} |
intravenous infusion of uro-egf was also effective in restoring cell proliferation when it was infused after the intestine had become hypoproliferative . beta-urogastrone/human epidermal growth factor administered through an intragastric cannulae thrice daily had no significant effect on intestinal weight or crypt cell production rate or metaphase collection . | process_includes_biological_process | {
"id": "C0596290",
"name": "cell proliferation",
"pos": [
64,
82
]
} | {
"id": "C0025564",
"name": "metaphase",
"pos": [
340,
349
]
} |
there is also a quantitative increase of ig-gene expression at the level of : ig gene transcription , mu- , kappa- and j-chain mrna accumulation , and ig translation and secretion . | process_includes_biological_process | {
"id": "C0017262",
"name": "gene expression",
"pos": [
44,
59
]
} | {
"id": "C0040649",
"name": "transcription",
"pos": [
86,
99
]
} |
these phenomena suggest that the psychological factors in cnv are the increase of mental load which is synthetically composed of expectancy , conation , motivation , orientation , attention and arousal , etc. , while engaging in an identical task . | process_includes_biological_process | {
"id": "C0004927",
"name": "conation",
"pos": [
142,
150
]
} | {
"id": "C0026605",
"name": "motivation",
"pos": [
153,
163
]
} |
likewise , in an in vitro transcription system , initiation of transcription at malpp required the presence of the malt protein and maltotriose along with the rna polymerase holoenzyme ; | process_includes_biological_process | {
"id": "C0040649",
"name": "transcription",
"pos": [
26,
39
]
} | {
"id": "C1158830",
"name": "initiation",
"pos": [
49,
59
]
} |
various features of the dna related to gene expression such as initiation and termination sites of transcription , receptor binding sites , a z-dna section , and exon/intron splicing sites were identified . | process_includes_biological_process | {
"id": "C0017262",
"name": "gene expression",
"pos": [
39,
54
]
} | {
"id": "C0597600",
"name": "termination",
"pos": [
78,
89
]
} |
in contrast to transcription in a spinach chloroplast extract , which requires initiation of exogenously added genes ( gruissem , w. , greenberg , b. m. , zurawski , g. , and hallick , r. b . ( 1983 ) cell 35 , 815-828 ) , rna synthesis in the run-on system is not affected by heparin or different salt concentrations . | process_includes_biological_process | {
"id": "C0040649",
"name": "transcription",
"pos": [
15,
28
]
} | {
"id": "C1328948",
"name": "rna",
"pos": [
223,
226
]
} |
a 2-year study of systemic and intestinal immunity to salmonella typhi was performed in 14 patients who were suffering from typhoid fever in an attempt to extrapolate the mechanism of immune responses in this disease . | process_includes_biological_process | {
"id": "C0020964",
"name": "immunity",
"pos": [
42,
50
]
} | {
"id": "C0301872",
"name": "immune responses",
"pos": [
184,
200
]
} |
mice with intact host defenses had an initial inflammatory response , consisting mostly of neutrophils , followed by a mononuclear cell infiltrate . | process_includes_biological_process | {
"id": "C0520990",
"name": "host defenses",
"pos": [
17,
30
]
} | {
"id": "C1155266",
"name": "inflammatory response",
"pos": [
46,
67
]
} |
the unusual transcription map of b19 suggests that regulation of the relative abundance of transcripts occurs by splicing and termination-polyadenylation events rather than by promoter strength . | process_includes_biological_process | {
"id": "C0040649",
"name": "transcription",
"pos": [
12,
25
]
} | {
"id": "C0949765",
"name": "polyadenylation",
"pos": [
138,
153
]
} |
the translational stimulation mediated by both means is shown to be restricted to the plasmid-derived mrnas because there is no qualitative or quantitative alteration in host protein synthesis . | process_includes_biological_process | {
"id": "C1519614",
"name": "translational",
"pos": [
4,
17
]
} | {
"id": "C0597295",
"name": "protein synthesis",
"pos": [
175,
192
]
} |
the yeast dna polymerase i transcript is regulated in both the mitotic cell cycle and in meiosis and is also induced after dna damage . | process_includes_biological_process | {
"id": "C1155839",
"name": "mitotic cell",
"pos": [
63,
75
]
} | {
"id": "C0025186",
"name": "meiosis",
"pos": [
89,
96
]
} |
subjects who reported out-of-control impulses or pathological intensity of relationships prior to seclusion and who showed positive change in mood , behavior , or thinking toward staff and/or other patients during or after seclusion seem to have benefited from the experience . | process_includes_biological_process | {
"id": "C0004927",
"name": "behavior",
"pos": [
149,
157
]
} | {
"id": "C0039869",
"name": "thinking",
"pos": [
163,
171
]
} |
the sequence of host-defense against microbial invasion consists of nonspecific active substances which are distributed diffusely in the body fluids and exert their functions quickly to eliminate microorganisms , nonspecific humoral elements capable of exerting their functions selectively at the site of microbial invasion , neutrophils , scavenger macrophages , protection at an early stage by igm antibody or a type of cell-mediated immunity ( primitive t cell response ) and protection at a late stage by typical immunities . | process_includes_biological_process | {
"id": "C0520990",
"name": "host-defense",
"pos": [
16,
28
]
} | {
"id": "C0020964",
"name": "immunities",
"pos": [
517,
527
]
} |
the partially deleted e1a can stimulate the expression of all early adenoviral genes as well as the cellular heat shock gene , the transcription of which is stimulated by ad5 e1a . | process_includes_biological_process | {
"id": "C0017262",
"name": "expression",
"pos": [
44,
54
]
} | {
"id": "C0040649",
"name": "transcription",
"pos": [
131,
144
]
} |
we have used cell survival , unscheduled dna synthesis , and alkaline elution to assess the capacity for dna repair in skin fibroblasts from normal control subjects , control subjects with central nervous system disease , and patients with alzheimer 's disease . | process_includes_biological_process | {
"id": "C0007620",
"name": "cell",
"pos": [
13,
17
]
} | {
"id": "C0012899",
"name": "dna repair",
"pos": [
105,
115
]
} |
by using unilateral lesions , thus avoiding total loss in any sensory modality , and examining a behavioural deficit not anyway thought to be , primarily , a consequence of sensory loss , it was hoped to arrive at an experimental test in which reinstatement of preoperative performance would necessarily reflect recovery rather than compensation . | process_includes_biological_process | {
"id": "C0004927",
"name": "behavioural",
"pos": [
97,
108
]
} | {
"id": "C0039869",
"name": "thought",
"pos": [
128,
135
]
} |
[ meso-inositol and cell division . i. effect of mesoinositol on the growth and mitosis of higher plants ] . | process_includes_biological_process | {
"id": "C0007590",
"name": "cell division",
"pos": [
20,
33
]
} | {
"id": "C0026255",
"name": "mitosis",
"pos": [
80,
87
]
} |
nutritional deficits do more damage to reproduction around the time of conception than later during pregnancy . | process_includes_biological_process | {
"id": "C0035150",
"name": "reproduction",
"pos": [
39,
51
]
} | {
"id": "C0009637",
"name": "conception",
"pos": [
71,
81
]
} |
the purified protein was active in an in vitro transcription assay , allowing specific initiation of transcription at the phi 29 a3 late promoter in the presence of bacillus subtilis sigma 43-rna polymerase holoenzyme . | process_includes_biological_process | {
"id": "C0040649",
"name": "transcription",
"pos": [
47,
60
]
} | {
"id": "C1158830",
"name": "initiation",
"pos": [
87,
97
]
} |
if immunological naiveness in term of protective immunity is the feature in cm patients , the immunoprecipitation test used is inadequate to demonstrate the fundamental differences in immune responses between cm and am patients . | process_includes_biological_process | {
"id": "C0020964",
"name": "immunity",
"pos": [
49,
57
]
} | {
"id": "C0301872",
"name": "immune",
"pos": [
184,
190
]
} |
the initial response of all cells was to undergo retraction of processes , behaviour thought to be linked with the depolymerization of microtubules which extend longitudinally through the processes . | process_includes_biological_process | {
"id": "C0004927",
"name": "behaviour",
"pos": [
75,
84
]
} | {
"id": "C0039869",
"name": "thought",
"pos": [
85,
92
]
} |
susceptible foals , those whose maternal immunity wanes before generation of their own immune response , readily develop disease if exposed aerogenously to sufficient numbers of r. equi . | process_includes_biological_process | {
"id": "C0020964",
"name": "immunity",
"pos": [
41,
49
]
} | {
"id": "C0301872",
"name": "immune response",
"pos": [
87,
102
]
} |
later studies of immune responses in bursaless chickens reported by lerner et al . contributed to our knowledge of bursa-independent humoral immunity and demonstrated an extra-bursal site for b-cell differentiation . | process_includes_biological_process | {
"id": "C0301872",
"name": "immune responses",
"pos": [
17,
33
]
} | {
"id": "C1511002",
"name": "b-cell differentiation",
"pos": [
192,
214
]
} |
these results confirm the view of the osteogenic histogenesis of psammous desmo-osteoblastoma , with an osteogenic differentiation of the tumour cells , bone formation and association of psammoma bodies which are not of bone origin . | process_includes_biological_process | {
"id": "C0178679",
"name": "histogenesis",
"pos": [
49,
61
]
} | {
"id": "C0007589",
"name": "differentiation",
"pos": [
115,
130
]
} |
although the histogenesis of this lesion is not known , it can be histologically differentiated from other pancreatic and retroperitoneal cysts . | process_includes_biological_process | {
"id": "C0178679",
"name": "histogenesis",
"pos": [
13,
25
]
} | {
"id": "C0007589",
"name": "differentiated",
"pos": [
81,
95
]
} |
the observed changes in effector and regulatory cell numbers may have implications for the acquisition of varicella-zoster virus infections , the immune deficiency state associated with the disease , and/or the immune response to resolve the infection . | process_includes_biological_process | {
"id": "C0020964",
"name": "immune",
"pos": [
146,
152
]
} | {
"id": "C0301872",
"name": "immune response",
"pos": [
211,
226
]
} |
it is concluded that histogenetic characteristics of malignant fibrous histiocytomas must be known to be able to establish more precise criteria on which the differentiation may be based . | process_includes_biological_process | {
"id": "C0178679",
"name": "histogenetic",
"pos": [
21,
33
]
} | {
"id": "C0007589",
"name": "differentiation",
"pos": [
158,
173
]
} |
our findings indicate that a suppression of fertility occurs in cotton-top tamarins living with their families , but that reproductive suppression does not affect the process of sexual maturation . | process_includes_biological_process | {
"id": "C0035150",
"name": "reproductive",
"pos": [
122,
134
]
} | {
"id": "C0036887",
"name": "sexual maturation",
"pos": [
178,
195
]
} |
the influence of the conditions detailed on fetal lung maturation was determined , lung development being enhanced until near term by rh immunization , rupture of membranes and hypertension with iugr . | process_includes_biological_process | {
"id": "C0678723",
"name": "maturation",
"pos": [
55,
65
]
} | {
"id": "C1160389",
"name": "lung development",
"pos": [
83,
99
]
} |
we have used such ablative procedures to define the t cell subsets which participate in graft rejection , graft-versus-host disease , antigenic competition and antiviral and anti-self immunity and have attempted to exploit such knowledge to establish immunological tolerance in an adult animal . | process_includes_biological_process | {
"id": "C0020964",
"name": "immunity",
"pos": [
184,
192
]
} | {
"id": "C0020963",
"name": "immunological",
"pos": [
251,
264
]
} |
the vectors consisted of the bovine papilloma virus-1 ( bpv-1 ) genome and t-pa transcriptional unit with a mouse metallothionein ( mt-1 ) promoter at the 5 ' end and mt-1 genomic sequences or sv40 early introns and polyadenylation signals at the 3 ' end . | process_includes_biological_process | {
"id": "C0040649",
"name": "transcriptional",
"pos": [
80,
95
]
} | {
"id": "C0949765",
"name": "polyadenylation",
"pos": [
216,
231
]
} |
thus , the restricted expression of these paternal genes in hybrid embryos is not the result of the persistence of stable maternal mrna species stored in eggs and not replaced by zygotic transcription . | process_includes_biological_process | {
"id": "C0017262",
"name": "expression",
"pos": [
22,
32
]
} | {
"id": "C0040649",
"name": "transcription",
"pos": [
187,
200
]
} |
transcription of the heat shock genes is increased when cells are exposed to high temperatures because of increased transcription initiation by sigma 32-rna polymerase . | process_includes_biological_process | {
"id": "C0040649",
"name": "transcription",
"pos": [
0,
13
]
} | {
"id": "C1158830",
"name": "transcription initiation",
"pos": [
116,
140
]
} |
we conclude that relative poly ( a ) site strength and the position of the poly ( a ) sites within the transcription unit , coupled with a changing concentration of a limiting factor , as well as transcription termination prior to the micron poly ( a ) site , all play a role in determining the expression of the mu locus during b-cell development . | process_includes_biological_process | {
"id": "C0040649",
"name": "transcription",
"pos": [
103,
116
]
} | {
"id": "C0597600",
"name": "transcription termination",
"pos": [
196,
221
]
} |
nightmare therapy , insofar as it has become an independent variety of psychological intervention , uses drug medication , which is able to suppress the symptom of the sufferer when on the drug , whereas behavioural and insight treatment not only eliminate the dreams , but can have an enduring healing effect . | process_includes_biological_process | {
"id": "C0004927",
"name": "behavioural",
"pos": [
204,
215
]
} | {
"id": "C0013117",
"name": "dreams",
"pos": [
261,
267
]
} |
however , in light of the fact that the behaviors to be altered are complex , usually well-established and repetitive , and require different skills to extinguish , the provision of typical hra feedback should not ( on a theoretical basis ) ordinarily be expected to accomplish much beyond information transmission , belief or attitude change , and the induction of some level of motivation . | process_includes_biological_process | {
"id": "C0004927",
"name": "behaviors",
"pos": [
40,
49
]
} | {
"id": "C0026605",
"name": "motivation",
"pos": [
380,
390
]
} |
in situ hybridization was used to show that the filaggrin precursor mrna is located precisely over the granular layer of the epidermis , indicating that expression of this gene is regulated at the transcriptional level as for the differentiation-specific keratin 1 protein . | process_includes_biological_process | {
"id": "C0017262",
"name": "expression",
"pos": [
153,
163
]
} | {
"id": "C0040649",
"name": "transcriptional",
"pos": [
197,
212
]
} |
transcription initiates 58 nucleotides upstream of the aug initiation codon , and the polyadenylation site occurs 100 nucleotides downstream of the termination codon . | process_includes_biological_process | {
"id": "C0040649",
"name": "transcription",
"pos": [
0,
13
]
} | {
"id": "C0949765",
"name": "polyadenylation",
"pos": [
86,
101
]
} |
thus , 1,25- ( oh ) 2d3 modulates mr 9000 cabp gene expression in at least two ways , a rapid transcriptional stimulation and a post-transcriptional effect preventing degradation of mr 9000 cabp transcripts and accounting for their accumulation several hours after the hormone treatment . | process_includes_biological_process | {
"id": "C0017262",
"name": "gene",
"pos": [
47,
51
]
} | {
"id": "C0040649",
"name": "transcriptional",
"pos": [
133,
148
]
} |
dietary carbohydrates are known to stimulate l-type pyruvate kinase gene expression at the transcriptional level in the liver . | process_includes_biological_process | {
"id": "C0017262",
"name": "gene",
"pos": [
68,
72
]
} | {
"id": "C0040649",
"name": "transcriptional",
"pos": [
91,
106
]
} |
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