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examination of mrna decay in cells treated with transcription inhibitors indicates that one c-fos mrna degradation pathway is dependent on rna synthesis , whereas the other is not . | process_includes_biological_process | {
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s1 mapping analysis revealed that the expression of the kmr gene was regulated at the transcriptional level . | process_includes_biological_process | {
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normal human subjects ( n = 7 ) breathing 21 % o2 ( normoxia ) , 13 % o2 ( hypoxia ) , or 100 % o2 ( hyperoxia ) performed repeated maximal inspiratory maneuvers ( inspiratory duration = 1.5 s , total breath duration = 3.5 s ) on an `` '' isoflow '' '' system , which delivered a constant mouth flow ( 1.25 or 1 l/s ) while maintaining normocapnia ( 5.5 % end-tidal co2 ) . | process_includes_biological_process | {
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the results showed that 1 ) except for inspiratory muscle endurance and fev1/fvc , men had greater respiratory muscle and pulmonary functions than women , 2 ) respiratory muscle function and pulmonary function decreased with age , 3 ) smoking tended to lower duty cycle and fev1/fvc and to enhance pe , mmax , and 4 ) inspiratory muscle endurance was greater in men who were physically active than in those who were sedentary . | process_includes_biological_process | {
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rtnf induces x-cgd gene expression in the myeloid cell lines acting , at least in part , at the transcriptional level , as shown in nuclear run-on experiments . | process_includes_biological_process | {
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these findings indicate that activated macrophages play a major role in host defense , although the fungus resists phagocytosis and remains in the extracellular milieu . | process_includes_biological_process | {
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the effect of actinomycin d and chloramphenicol was studied at the level of rna transcription and translation . alpha-amylase synthesis in bacillus licheniformis ccm 2205 was practically not altered during the first 20 min after the addition of actinomycin d , although rna synthesis was almost completely blocked . | process_includes_biological_process | {
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upstream of at least some telomere-linked genes for the variant surface glycoproteins ( vsgs ) of african trypanosomes are expression site associated genes ( esags ) whose transcription is co-ordinated with the transcription of the adjacent vsg gene [ cully et al . ( 1985 ) cell 42 , 173-182 ] . | process_includes_biological_process | {
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the article expresses the view that late motherhood , beginning shortly before the end of the reproductive phase , is related to a particular problem of inner maturation among late mothers . | process_includes_biological_process | {
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development and distribution of serotonin in the central nervous system of manduca sexta during embryogenesis . | process_includes_biological_process | {
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development and distribution of serotonin in the central nervous system of manduca sexta during embryogenesis . | process_includes_biological_process | {
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correlation of these data with the development of germ cells during rat testicular maturation suggests that the high odc activity in both sertoli and germ cells is associated mainly with cell proliferation while the increase in adometdc activity is most likely associated with the maturation of sertoli cells and the meiosis of germ cells , particularly the formation of pachytene spermatocytes and the meiotic cell division of spermatocytes into spermatids . | process_includes_biological_process | {
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respondents emphasized the crucial role of feedback and confrontation by staff and co-residents in changing their unhelpful behaviour and attitudes , although a few thought that confrontations were too forceful . | process_includes_biological_process | {
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treatment of splenic b lymphoid cells with lps plus il-4 induces the expression of transcripts from the germ line epsilon transcription unit followed by expression of normal immunoglobulin epsilon heavy-chain mrna . | process_includes_biological_process | {
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moreover this protein fraction , containing eusf , transactivates the expression of the duck h5 gene in vitro and elimination of the usf-consensus sequence leads to a loss of stimulation but retains the basic transcription of the gene . | process_includes_biological_process | {
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this behavioral hypersensitivity ( bh ) is thought to reflect an increase in da receptor number following chronic pharmacologic denervation . | process_includes_biological_process | {
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however , n-cadherin rna rapidly appeared in ectoderm exposed to a heterologous neural inducer , indicating that n-cadherin expression , as an early response to induction , precedes the morphogenetic events associated with early neural development . | process_includes_biological_process | {
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these results are consistent with the hypothesis that the morphogenetic changes associated with early neural development are controlled , in part , by the induced expression of n-cadherin in the neural plate . | process_includes_biological_process | {
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this effect was found both in the reproductive plans reported by the parents and in the occurrence of pregnancies during the follow-up interval . | process_includes_biological_process | {
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the gene comprising a total of 7766 nucleotides ( nt ) from the transcription start point , determined by primer extension analysis , to the polyadenylation site , determined from cdna sequencing , and a 1030-nt 5 ' upstream region have been sequenced . | process_includes_biological_process | {
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typical multidrug resistance in human and animal cell lines is caused by overactivity of an unidirectional transmembrane drug efflux pump , encoded by the mdr genes , called mdr genes in mice and humans and pgp genes in hamsters . | process_includes_biological_process | {
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as part of an investigation of the mechanisms controlling gene expression during lineage commitment , we have investigated the transcriptional status of hematopoietic lineage-specific genes and the interactions of early hematopoietic progenitor cells with stromal cells of the marrow microenvironment . | process_includes_biological_process | {
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this was confirmed by run-off transcription assays showing a restoration of c-fos and c-myc rna synthesis when actinomycin d was displaced by proflavine . | process_includes_biological_process | {
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in cells that eventually die , total transcription , polyadenylated [ poly ( a ) + ] rna synthesis , and protein synthesis were markedly inhibited only after 48 hours . | process_includes_biological_process | {
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expression of the yeast dna primase gene , pri1 , is regulated within the mitotic cell cycle and in meiosis . | process_includes_biological_process | {
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in the group treated by assisted reproduction , 81 pregnancies were singleton and nine were multiple gestations , whereas in the routine group , 84 were singleton and two were multiple gestations . | process_includes_biological_process | {
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in the group treated by assisted reproduction , 29 of 90 gestations ( 32 % ) ended before 24 weeks , compared with 18 of 86 ( 21 % ) in the routine group , a nonsignificant difference . | process_includes_biological_process | {
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the g transcription stop/polyadenylation consensus signal in sad b19 is destroyed by a deletion of three a residues . | process_includes_biological_process | {
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in 1988/89 the institute for development planning and structural research at the university of hanover carried out five regional case studies into the sports behaviour of the elderly and into their motives and expectations with regard to sport . | process_includes_biological_process | {
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the similarity of ercc2 and rad3 suggests a role for ercc2 in both cell viability and dna repair and provides the first insight into the biochemical function of a mammalian nucleotide excision repair gene . | process_includes_biological_process | {
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the similarity of ercc2 and rad3 suggests a role for ercc2 in both cell viability and dna repair and provides the first insight into the biochemical function of a mammalian nucleotide excision repair gene . | process_includes_biological_process | {
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expression of the rat protamine 2 gene is suppressed at the level of transcription and translation . | process_includes_biological_process | {
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successful pregnancy in the female rat depends upon two sets of physiological events : ( 1 ) transport of gametes ( sperm and egg ) through the reproductive tract so that fertilization can be effected and ( 2 ) establishment of an appropriate hormonal environment ( progestational state ) so that the fertilized egg can implant in the uterus and be maintained during subsequent gestation . | process_includes_biological_process | {
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} | {
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this model system shows that a protein-dna complex can block the passage of rna polymerase ii , and offers some insight into the control of eukaryotic gene expression during transcription elongation , a phenomenon observed in a variety of systems . | process_includes_biological_process | {
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} | {
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the current dramatic increase in illicit cocaine use by individuals during their reproductive years has heightened concerns over the possible adverse effects of maternal cocaine abuse during pregnancy . | process_includes_biological_process | {
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} | {
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clinical and reproductive effects of clophen a50 ( pcb ) administered during gestation on pregnant guinea pigs and their offspring . | process_includes_biological_process | {
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} | {
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in the context of htlv-1 gene expression , the u5 element would repress expression of unspliced genomic rna of htlv-1 , but not subgenomic rna . | process_includes_biological_process | {
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in transient gene expression assays we observed an increase in expression of the bacterial chloramphenicol acetyl-transferase ( cat ) gene , under the transcriptional control of the hiv-1 ltr ( pltr-cat ) , when this plasmid was cotransfected into vero or mrc-5 cells with a plasmid containing either the hcmv immediate early 1 and 2 ( e1 , ie2 ) genes ( prl43a ) or just the ie2 gene ( pmp18 ) . | process_includes_biological_process | {
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} |
such gene targeting methods will allow replacement of normally functioning murine genes with genes altered with precise mutations involving many aspects of gene expression , including transcription , processing and protein-protein interactions . | process_includes_biological_process | {
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} | {
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} |
studies on the mechanisms of fcf action using behavioural and biochemical methods have shown that all stimulant effects produced by acute administration of fcf are thought to be due to indirect activation of da systems in cns . | process_includes_biological_process | {
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nucleotide sequence analysis revealed a complete transcription unit composed of a cat box , a tata box , a ribosome-binding sequence , a polyadenylation signal and an open reading frame ( orf ) of 2940 bp transcribed from left to right . | process_includes_biological_process | {
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} | {
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} |
the 3.5-kilobase transcript terminated near the rho-independent terminator structure between lkta and lktb , but transcription may continue , via antitermination or de novo transcription initiation , into the downstream lktb and lktd genes . | process_includes_biological_process | {
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} | {
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the results have implications for behavioral ecology , behavioral economics , motivation , and the methodology of reward . | process_includes_biological_process | {
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} | {
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[ gas exchange and ventilation at rest during physical exertion in free and artificially impeded respiration . ii . obstruction of inspiratory respiration ] . | process_includes_biological_process | {
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} | {
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despite activation of the renin-angiotensin-aldosterone system and the sympathetic nervous system , two strong pressor systems , the only circulatory reaction was a decrease in diastolic blood pressure . | process_includes_biological_process | {
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} | {
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in most of the patients the obstruction was reversible as shown by respiration parameters upon inhalation of broncholytics with various mechanisms of action . | process_includes_biological_process | {
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} | {
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basing on the findings gained at investigation of external respiration with measurement of the forced expiration rate in a large group of chronic bronchitis sufferers , subjects exposed to occupational respiratory irritants and in healthy subjects , the conclusion was made on a high informative content in relation to chronic bronchitis diagnosis of a maximal expiration rate at the level of 75 % expiratory vital capacity , especially in combination with tiffeneau test . | process_includes_biological_process | {
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} | {
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based on amino acid sequence analysis , each of these attractants has been assigned to one of two distinct families of cytokines that are thought to participate in host defense and inflammatory responses . | process_includes_biological_process | {
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} | {
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} |
i conclude that the heat shock-induced depression of gene expression is an event taking place at the initiation of translation . | process_includes_biological_process | {
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} | {
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the possible involvement of antisense rna transcription in the pathway that controls the programmed expression of chorion genes at the level of transcription initiation or post-transcriptional processing is discussed . | process_includes_biological_process | {
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} | {
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the possible involvement of antisense rna transcription in the pathway that controls the programmed expression of chorion genes at the level of transcription initiation or post-transcriptional processing is discussed . | process_includes_biological_process | {
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} | {
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} |
an immune response cascade that is t cell independent begins with the stimulation of virgin lymphocytes by antigen to differentiate into large lymphocytes . | process_includes_biological_process | {
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} | {
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nrdb gene expression was stimulated by dna damage only when its transcription was from the nrda promoter , but there was no effect when nrdb was transcribed from its own promoter . | process_includes_biological_process | {
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} | {
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} |
the importance of the vys during development is emphasized by the embryotoxicity resulting from exposure to agents which cause vys dysfunction when administered to the pregnant animal during organogenesis . | process_includes_biological_process | {
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} | {
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} |
in comparison to the controls , the three highest methoxychlor doses also significantly increased the weights of the reproductive tracts and stimulated their development . | process_includes_biological_process | {
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} | {
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} |
we thus conclude that in humans 1 ) the transversus abdominis is recruited preferentially to the superficial muscle layer of the abdominal wall during breathing and 2 ) the threshold for abdominal muscle recruitment during expiration is substantially lower than conventionally thought . | process_includes_biological_process | {
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} | {
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} |
even though breathing appeared to be an expiratory act , there remained a significant component of active inspiratory diaphragmatic shortening , and the major portion of vt was produced during active inspiration . | process_includes_biological_process | {
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} | {
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} |
even though breathing appeared to be an expiratory act , there remained a significant component of active inspiratory diaphragmatic shortening , and the major portion of vt was produced during active inspiration . | process_includes_biological_process | {
"id": "C0035203",
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} | {
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} |
low frequency oscillations in respiration were induced in healthy sleeping adult subjects via the administration of a bolus of co2 during inhalation . | process_includes_biological_process | {
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} | {
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} |
these results suggest that nk cell activation induced during antiviral immunity is distinct from activation elicited during an antitumor response . | process_includes_biological_process | {
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} | {
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} |
we describe a partially fractionated in vitro transcription system from xenopus laevis for the assay of transcription termination by rna polymerase i . | process_includes_biological_process | {
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} | {
"id": "C0597600",
"name": "transcription termination",
"pos": [
104,
129
]
} |
these results are consistent with a model linking actin gene expression to cell growth by regulating transcription during the g1 and mrna decay during the g2 phase of the cell cycle . | process_includes_biological_process | {
"id": "C0017262",
"name": "gene expression",
"pos": [
56,
71
]
} | {
"id": "C0040649",
"name": "transcription",
"pos": [
101,
114
]
} |
the expression of the pox1 gene is regulated at the level of transcription , and is induced more than 25-fold by the addition of oleic acid to the medium . | process_includes_biological_process | {
"id": "C0017262",
"name": "expression",
"pos": [
4,
14
]
} | {
"id": "C0040649",
"name": "transcription",
"pos": [
61,
74
]
} |
firstly , those factors that enable bacteria to resist or avoid host defence mechanisms , including opsonization , phagocytosis , intracellular killing and terminal complement lysis of bacterial cell walls , are described . | process_includes_biological_process | {
"id": "C0520990",
"name": "host defence",
"pos": [
64,
76
]
} | {
"id": "C0031308",
"name": "phagocytosis",
"pos": [
115,
127
]
} |
the construct was defined as the expectancy that some behavior or cognition will alleviate a negative mood state . | process_includes_biological_process | {
"id": "C0004927",
"name": "behavior",
"pos": [
54,
62
]
} | {
"id": "C0009240",
"name": "cognition",
"pos": [
66,
75
]
} |
it is supposed that a part of cytoplasmic hbvdna was on replicative phase with gene production expression , on the contrary , another part of cytoplasmic hbvdna may be out of replication with no gene product expression during chronic hepatitis b . | process_includes_biological_process | {
"id": "C0017262",
"name": "gene",
"pos": [
79,
83
]
} | {
"id": "C1171362",
"name": "gene product expression",
"pos": [
195,
218
]
} |
we report here that overexpression of eif-4e in nih 3t3 and rat 2 fibroblasts causes their tumorigenic transformation as determined by three criteria : formation of transformed foci on a monolayer of cells ; | process_includes_biological_process | {
"id": "C0007621",
"name": "tumorigenic transformation",
"pos": [
91,
117
]
} | {
"id": "C1510411",
"name": "transformed",
"pos": [
165,
176
]
} |
thus , apparent differences between the two groups of females in the extent to which hormones control copulatory behavior does not stem from differences in hormonal regulation of female sexual motivation but from the physical ability of primate , but not rodent , females to mate without hormonal stimulation . | process_includes_biological_process | {
"id": "C0004927",
"name": "behavior",
"pos": [
113,
121
]
} | {
"id": "C0026605",
"name": "motivation",
"pos": [
193,
203
]
} |
to gain an insight into the possible involvement of the cytoskeletal components and cellular junctions in morphogenetic processes during development , we have studied the spatio-temporal distribution of two major adherens-junction-associated molecules , vinculin and talin , during avian embryogenesis , using immunofluorescence microscopy and immunoblotting . | process_includes_biological_process | {
"id": "C0678723",
"name": "development",
"pos": [
137,
148
]
} | {
"id": "C0013936",
"name": "embryogenesis",
"pos": [
288,
301
]
} |
the present studies demonstrate that increased hsp70 gene expression is due to its heightened transcription rate . | process_includes_biological_process | {
"id": "C0017262",
"name": "gene expression",
"pos": [
53,
68
]
} | {
"id": "C0040649",
"name": "transcription",
"pos": [
94,
107
]
} |
these findings suggest that disturbances in cerebral energy metabolism induced by temporary ischemia may be caused by inhibition of the glycolytic pathway that is hardly reversed by unforced reperfusion and , therefore , results in permanent damage . | process_includes_biological_process | {
"id": "C0014272",
"name": "energy metabolism",
"pos": [
53,
70
]
} | {
"id": "C1512232",
"name": "inhibition of",
"pos": [
118,
131
]
} |
[ a histogenetic study of the inner ear in the human embryo and fetus -- innervation and differentiation of the sensory epithelium ] . | process_includes_biological_process | {
"id": "C0178679",
"name": "histogenetic",
"pos": [
4,
16
]
} | {
"id": "C0007589",
"name": "differentiation",
"pos": [
89,
104
]
} |
attention is drawn to evidence from a wide range of studies on the effect of ethanol , acetaldehyde ( its primary metabolite ) , and anaesthetics on cell division and chromosome segregation in an attempt to substantiate an hypothesis regarding the mode of action of these agents . | process_includes_biological_process | {
"id": "C0007590",
"name": "cell division",
"pos": [
149,
162
]
} | {
"id": "C0598175",
"name": "chromosome segregation",
"pos": [
167,
189
]
} |
this behaviour is thought to be triggered by activity of sensory fibres ending in a neuroma . | process_includes_biological_process | {
"id": "C0004927",
"name": "behaviour",
"pos": [
5,
14
]
} | {
"id": "C0039869",
"name": "thought",
"pos": [
18,
25
]
} |
the mean decrease in sound amplitude when breathing he-o2 compared to air was : trachea , inspiration 44 % ; | process_includes_biological_process | {
"id": "C0035203",
"name": "breathing",
"pos": [
42,
51
]
} | {
"id": "C0004048",
"name": "inspiration",
"pos": [
90,
101
]
} |
in experiments designed to study the mechanism by which peptide hormones binding to their plasma membrane receptors stimulate the expression of specific genes , the transcription of two neuroendocrine genes , prolactin and growth hormone , was analyzed in a rat pituitary cell line . | process_includes_biological_process | {
"id": "C0017262",
"name": "expression",
"pos": [
130,
140
]
} | {
"id": "C0040649",
"name": "transcription",
"pos": [
165,
178
]
} |
we have assessed the uniformity of regional ventilation during tidal breathing using continuous inhalation of krypton-81m in 43 male , lifelong nonsmokers and 46 male , current cigarette smokers ( mean daily consumption 24.1 cigarettes/day ) between 44 and 61 yr of age and with mild or no respiratory symptoms . | process_includes_biological_process | {
"id": "C0035203",
"name": "breathing",
"pos": [
69,
78
]
} | {
"id": "C0004048",
"name": "inhalation",
"pos": [
96,
106
]
} |
professional preparation of instructions in areas such as educational psychology ( learning and memory , motivation , and skill acquisition ) met with the approval of the participants , but no detectable change in instructional methods resulted . | process_includes_biological_process | {
"id": "C0023185",
"name": "learning",
"pos": [
83,
91
]
} | {
"id": "C0026605",
"name": "motivation",
"pos": [
105,
115
]
} |
these findings define the in vivo terminus of an elongated rna and establish that human beta-globin transcription may extend at least 900 nucleotides 3 ' of the normal polyadenylation site . | process_includes_biological_process | {
"id": "C0040649",
"name": "transcription",
"pos": [
100,
113
]
} | {
"id": "C0949765",
"name": "polyadenylation",
"pos": [
168,
183
]
} |
the rapid production of fully functional cholecalcin mrna , which was detectable as early as 1 h after a single dose of calcitriol to vitamin-d-deficient rats , provides convincing evidence that calcitriol increases 9-kda cholecalcin production by increasing cholecalcin gene expression at the transcriptional level . | process_includes_biological_process | {
"id": "C0017262",
"name": "gene",
"pos": [
271,
275
]
} | {
"id": "C0040649",
"name": "transcriptional",
"pos": [
294,
309
]
} |
light and electron microscopic studies show that the transplants undergo histogenetic differentiation , resulting in the development of mature inner and outer layer neurons and muller glial cells . | process_includes_biological_process | {
"id": "C0178679",
"name": "histogenetic",
"pos": [
73,
85
]
} | {
"id": "C0007589",
"name": "differentiation",
"pos": [
86,
101
]
} |
thus , reproductive performance and profit respond positively to improvements of rates of detection of estrus , improvements of rates of conception , and improvements of management of the periparturient cow . | process_includes_biological_process | {
"id": "C0035150",
"name": "reproductive",
"pos": [
7,
19
]
} | {
"id": "C0009637",
"name": "conception",
"pos": [
137,
147
]
} |
the effect of the peptide antibiotic gramicidin s , produced by bacillus brevis nagano , was tested on the transcription system of the producer by using in vivo , semi in vitro and in vitro systems for studies of rna synthesis . | process_includes_biological_process | {
"id": "C0040649",
"name": "transcription",
"pos": [
107,
120
]
} | {
"id": "C1328948",
"name": "rna synthesis",
"pos": [
213,
226
]
} |
the following section deals with the influence of cognition and affect , as well as perception on these same physiological parameters during exercise . | process_includes_biological_process | {
"id": "C0009240",
"name": "cognition",
"pos": [
50,
59
]
} | {
"id": "C0030971",
"name": "perception",
"pos": [
84,
94
]
} |
[ variations of the time of alveolar air formation and alveolar ventilation during respiration against inspiratory and expiratory resistance ] . | process_includes_biological_process | {
"id": "C0035203",
"name": "respiration",
"pos": [
83,
94
]
} | {
"id": "C0004048",
"name": "inspiratory",
"pos": [
103,
114
]
} |
[ variations of the time of alveolar air formation and alveolar ventilation during respiration against inspiratory and expiratory resistance ] . | process_includes_biological_process | {
"id": "C0035203",
"name": "respiration",
"pos": [
83,
94
]
} | {
"id": "C0231800",
"name": "expiratory",
"pos": [
119,
129
]
} |
the present study was undertaken to define hormonal conditions for in vitro maturation that support subsequent fertilization and embryonic development . | process_includes_biological_process | {
"id": "C0678723",
"name": "maturation",
"pos": [
76,
86
]
} | {
"id": "C0013936",
"name": "embryonic development",
"pos": [
129,
150
]
} |
we conclude that this sequential regimen of human gonadotropins provides a cohort of oocytes from rhesus monkeys that will complete meiotic maturation and fertilize in vitro , with embryonic development proceeding in vitro and in vivo . | process_includes_biological_process | {
"id": "C0678723",
"name": "maturation",
"pos": [
140,
150
]
} | {
"id": "C0013936",
"name": "embryonic development",
"pos": [
181,
202
]
} |
these findings suggest that sp1 and sp3 as a natural endogenous immunoregulators may play an important role in reproductive strategy of human gestation . | process_includes_biological_process | {
"id": "C0035150",
"name": "reproductive",
"pos": [
111,
123
]
} | {
"id": "C0032961",
"name": "gestation",
"pos": [
142,
151
]
} |
these results suggested that the energy metabolism in neonatal muscle depends on anaerobic glycolysis rather than the oxidative phosphorylation and also suggested that , though histochemical characteristics remain the same , biochemical properties change during the course of muscle development . | process_includes_biological_process | {
"id": "C0014272",
"name": "energy metabolism",
"pos": [
33,
50
]
} | {
"id": "C0017952",
"name": "anaerobic glycolysis",
"pos": [
81,
101
]
} |
mitosis and cell division are the final events of the cell cycle , resulting in the precise segregation of chromosomes into two daughter cells . | process_includes_biological_process | {
"id": "C0007590",
"name": "cell division",
"pos": [
12,
25
]
} | {
"id": "C0598175",
"name": "segregation",
"pos": [
92,
103
]
} |
a comparison of the two procedures with respect to the respiratory function , assessed by spirometry , blood gas analysis , inspiratory and expiratory pressures , and thoraco-abdominal respiratory synchronism , was made in two groups of patients after surgery on the abdominal aorta . | process_includes_biological_process | {
"id": "C0035203",
"name": "respiratory function",
"pos": [
55,
75
]
} | {
"id": "C0004048",
"name": "inspiratory",
"pos": [
124,
135
]
} |
a comparison of the two procedures with respect to the respiratory function , assessed by spirometry , blood gas analysis , inspiratory and expiratory pressures , and thoraco-abdominal respiratory synchronism , was made in two groups of patients after surgery on the abdominal aorta . | process_includes_biological_process | {
"id": "C0035203",
"name": "respiratory function",
"pos": [
55,
75
]
} | {
"id": "C0231800",
"name": "expiratory",
"pos": [
140,
150
]
} |
the effect of the comorbidity of overanxious disorder ( anx ) in attention deficit hyperactivity disorder ( adhd ) on laboratory measures of behavior , cognition , and stimulant response was examined . | process_includes_biological_process | {
"id": "C0004927",
"name": "behavior",
"pos": [
141,
149
]
} | {
"id": "C0009240",
"name": "cognition",
"pos": [
152,
161
]
} |
insertion mutations in frzcd lowered gene expression whether they were upstream or downstream of the reporter tn5-lac , suggesting that the frzcd protein regulates transcription of the entire operon from a promoter upstream of frza . | process_includes_biological_process | {
"id": "C0017262",
"name": "gene expression",
"pos": [
37,
52
]
} | {
"id": "C0040649",
"name": "transcription",
"pos": [
164,
177
]
} |
in contrast , the nucleosomal core lacking the amino-terminal ends of histones , which has an affinity for polymerase equal to that of the h2a.h2b-deficient core , shows transcription properties similar to those of the whole nucleosomal core , with synthesis of short rna chains ( 40 nucleotides or less ) . | process_includes_biological_process | {
"id": "C0040649",
"name": "transcription",
"pos": [
170,
183
]
} | {
"id": "C1328948",
"name": "synthesis",
"pos": [
249,
258
]
} |
dna sequences involved in the expression of the agropine synthase gene ( ags ) of t-dna were identified by analysis of transcriptional activity of promoter mutants in crown gall tumors of sunflower . | process_includes_biological_process | {
"id": "C0017262",
"name": "expression",
"pos": [
30,
40
]
} | {
"id": "C0040649",
"name": "transcriptional",
"pos": [
119,
134
]
} |
studies of the time course of the immune status characteristics after praziquantel treatment and of the nature of its side-effects on various groups of opisthorchiasis patients in the focus established significant differences in their immune response to specific treatment . | process_includes_biological_process | {
"id": "C0020964",
"name": "immune status",
"pos": [
34,
47
]
} | {
"id": "C0301872",
"name": "immune response",
"pos": [
235,
250
]
} |
the analysis pointed out the reactivity of these systems , their histogenesis and dynamics , their cellular composition and reactional capacity of composing cells , the relations between different groups of cells forming the system ( intrasystemic relationships ) , those between proliferation and differentiation-maturation , the multifactorial determinism of proliferation , differentiation , maturation and mobilization of the cells composing the system . | process_includes_biological_process | {
"id": "C0178679",
"name": "histogenesis",
"pos": [
65,
77
]
} | {
"id": "C0007589",
"name": "differentiation",
"pos": [
377,
392
]
} |
these findings reinforce the hypothesis that abrb represses gene expression through its direct interaction with the transcription initiation regions of genes under its control . | process_includes_biological_process | {
"id": "C0017262",
"name": "gene expression",
"pos": [
60,
75
]
} | {
"id": "C1158830",
"name": "transcription initiation",
"pos": [
116,
140
]
} |
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