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Switching from Prozac to Wellbutrin
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I’ve been prescribed Prozac for almost 3 years, I feel like the first two years or so it did wonders for my mental health but recently it’s kind of been wearing off, so to speak or just not working as well when I first started. Ive been in a rut lately, not feeling all that great.
I’ve been talking to my doctor and we’ve discussed trying Wellbutrin but I’m a little apprehensive about trying something new and just getting accustomed to a new medication and everything that comes with that. I wanted to know if anybody else has success switching to Wellbutrin? or just their experience in general.
| 1 |
Long term AD users. delayed side effects?
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I'm curious to know, those who have been on anti-depressants for a few years, have you noticed any side effects that have only come to fruition much later on?
Like many people, I went through hell going on Sertraline 6 years ago. Once the side-effects left me, I didn't notice much until the last 2 years or so.
The last 8 months, my libido has completely gone. My emotions are more muted than they ever have been, and I've a burning sensation on my tongue everyday that has been persistent for about a year.
The tongue issue might not be the AD's, but intuitively I think it is (There's nothing physically wrong with my tongue and I eat healthily).
| 3 |
Potentially akathisia - should be concerned?
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Hi again.
I've been on aripiprazole for a little over a month now, bit my dose (2.5 mg) has been truly stable for the past 1.5-2 weeks. I've been experiencing muscle jerks here n there, but nothing where I felt like it was unbearable. Weirdly, if I rubbed my eye for too long the eyelid would twitch, but since it normally didn't last, I dismissed it. The jerks would get more frequent if caffeine was consumed.
Today, however, I am pretty sure I have experienced akathisia? I had an annoying tic in my heel every time I tried to rest and during the night it didn't stop. Also was rolling in my bed endlessly and felt restless in my legs. At a 2 hour mark, I measured my heart rate and it was up to 95 (I take aripiprazole at night, btw).
Only managed to fall asleep after an hour of taking gabapentin.
Should I be concerned? I could try to wait it out in case it's temporary or lower my dose back to 1.25 mg, although I am not sure if it would be enough for me.
| 2 |
Eat in 10 Minutes at Home
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One of the struggles with depression is getting enough nutrients or calories for a given day. I recently figured out a pretty straight forward meal anyone can eat day in and day out.
Bean Burrito. 3 Ingredients: Canned beans (any kind) Wheat Tortilla (watch the sodium usually get 12% DV others are much higher), fresh shredded cheese (buy it already shredded).
Directions: shredded cheese on tortilla on pan with low/medium heat wait till it melts (1-2 minutes), drain beans and microwave for 2:22, put beans on melted cheese eat. Total time including eating is like 10 minutes
I usually eat two of these then finish the beans. Meal is about 800 calories so you're set for about half or a third of your caloric needs for the day. You can also add salsa and sour cream but I don't because so far I like to keep it simple to 3 ingredients.
I think this is infinitely healthier than fast food because here you're working with 3 ingredients and even something basic like a bean burrito at any fast food place has many many ingredients as well as tons of sodium.
Edit: I see other people have their own recipes for lightning fast meals. Share your own below!
| 23 |
How do people keep going trying treatment after treatment?
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Hi, I (36M and on 150mg clomipramine and 250mg quetiapine) come on this sub quite a bit and often see posts by people saying something along the lines of 'oh yeah, I've tried SSRIs, SNRIs, MAOIs, TCAs, mood stabilisers, antipsychotics and nothing has worked'.
Like how do people keep going trying treatment after treatment? The nature of my depression is that it is really quite severe and I have really low energy, no motivation, hopeless. Doesn't the nature of depression make it so hard to continue to pursue treatment? And the fact that trying a new treatment could make your depression worse perhaps even causing suicide? Sometimes I just lie there staring at the wall feeling like I've accepted that I will feel like this forever :-(
| 7 |
Does Alcohol make anyone more outgoing ?
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I am like a procrastinator and it sucks because I know what I have to do but take my sweet ass time on every task. Whenever I have a drink, I am like ready to work, ready to try things, and its so weird.
Anyone else have this issue? Is this normal?
| 4 |
Has Anyone Had Success With Moclobemide?
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Hi,
I suffer from Depression and Social Anxiety. After dozens of failed medication, my psychiatrist prescribed me Moclobemide before we take the next step with Nardil or Parnate. So my question is, did anyone get relief from Moclobemide? If yes, please describe the effects you got from it.
| 2 |
Autocracy in indian medical colleges
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Today, we had our pediatric posting class. Today is the 3rd day and this is the first time this case(rheumatic heart disease) is presented.. A short, dark, well dressed and spectacled teacher entered the classroom, who made us wonder, what made the previous batch students say, she was arrogant and terrifying.
We students doing final year, were between the age groups of 21-24 year old adults. We were prepared well enough to answer the expected questions.
Presentation started and she started thrashing each and everyone, one by one, merciless. She did not use badwords, otherwise hurt everyone as much as she can with words. She even thrashed 3 students to exit the class and stand outside for helping out their friends to answer. She threatened to put absent, if they don't get out immediately!
Some phrases she used, ' eruma maadu maari dhandama irukeenga'(lazy as a Buffalo) ; ' urupada maateenga' ( u won't improvise in life) ; ' mannu mari(as useless as sand)!!
She never showed any intention of helping and educating the students. She seemed to purposefully hurt everyone.
Is it that, she has some psychiatric problem or its her nature. Well we don't care! We don't agree on expressing herself to us in that way!
Even though we answered some question, she never cared about our knowledge or appreciated
She always found ways to thrash us with following question!
Why can't we speak back or cannot show any resistance?
Answer: Autocracy
We study in a govt medical college. There is no need for any reputation, there is always a for seats. So, the professors care about nothing. If we answer back or show any resistance, they won't hesitate failing us in practicals and make us wait for another 6 months.
Who would dare to waste 6 months to stand for their dignity and not feeding the ego of professors. Such a miserable state for us.
She is not the only professor or this isn't the only kind of issue...
As adults, we care about our lives. With a lot more problems, personally, financially in families and academically, we are matured enough to find and work towards a solution. Mental health is already in stake while doing this course. Whearas my friends already got jobs and startes supporting their families, We still are dependent on our families which makes us already weak socially!
We don't expect some one to thrash and insult us bad to make us realize our state and problems.
We dont mind getting punished by assignments or presenting seminars, which will help us learn, if we really did commit any questioanable mistake. We neither mind getting less marks or getting suspended or even get failed, if we really deserve it. But we can never tolerate insults and inability to stand up and question against them!
Hope, this issues recieves important attention, before the contents of this article gets into suicide note of some innocent medico!!!
| 2 |
How much Clonazepam and how oftern can one take it without the tolerance building up?
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I'm looking for a way to take it that is \*sustainable\* in the long term, as no other medication or therapy seems to be working on me.
Over the years I've been on about 25 different antidepressants. I've been attending different kinds of therapy, doing mindfulness, working out etc. I've been diagnosed with either treatment resistant depression, some unspecified kind of personality disorder, or my therapist friend thinks I could have CPTSD.
The current daily medication (agomelatine, quetiapine, mianserin) at least finally improved the quality of my sleep, but that's it. The only thing that helps me feel like existence isn't constant suffering are benzos. But when I take them too often, they stop working. I wasn't successful in finding a study that I could use to figure out how many good days a week I can afford, or someting like that...
| 3 |
Treatments for inability to concentrate?
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I was diagnosed with depression long ago. On top of that, I am also diagnosed with an unspecified personality disorder.
However, the biggest issue that I am facing is my inability to focus. My mind operates on auto pilot mode almost the whole time.
Does anyone know if there are any treatments or resources that tackle this?
| 1 |
Cold Water is Saving My Life
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Been suffering from depression for I don't even know how long. I recently started getting better and I realised I don't remember feeling this content or happy. So I must've been like this for ages. You have no idea how world and perception changing it is for a person to experience this (*well many of you hopefully do*). To normal people I think, this is what all of you lucky fuckers have been feeling all this time? Not even, I'm still not out of it, so it only gets better.
A MAJOR cause of my improvemnt is cold water. I was numb, no feeling in my brain. Cold water hitting my skin shocks my brain. Gives it stimulation. Makes me feel. Gives me SENSATION. I feel ALIVE. I love the pain, any feeling, they are so tasteful and beautiful. No one but the Hitlers of the world should lose the ability to have them. Few months ago I would have never thought my routine would be so good. I was in bed 100% of the day, eating, thinkiing of sucide and slowly withering away. Now, I wake up at 5:30 am, get into a freezing cold shower. I jump right in, takes me a while to hype myself up for it, but I don't want to slowly get use to it, I want the cold shock and parts of my face going numb. Stay in for 10 minutes, then I go for a 30 min run. This entire period is my highlight of my day. It feels so good. I get pretty emotional sometimes. I think it's cuz I like feeling emotional after such a long period of numbness. I will sometimes scream or cry while running, it FEELS so good. Pretty sure my neighbors think I've gone coocoo. I can only do this cuz of the 10 min cold shower in the morning. I use it to snow ball. Upon waking, I feel dull, numb and lazy. Right after the shower, I feel energetic and happy. I use this to go on a run.Then some times I go for a hike as well. All of this gives me enough dopamine to last like half a day. Being happy for half a day is amazing improvement for me.
What about the other half? I now go to swim in a beach near by. I live in Ireland so all water here is really cold, even in summer. I love it. I'm getting so good at swimming as well. Either way, that gives me enough happiness to last the rest of the day. Imma keep this routine and hopefully keep building on it until I eventually get a job and start building a life for myself. I have 1 year to get better. I took a gap year from my course. I'm studing medicine and I now I cannot believe I managed to get and stay in it with how miserable I was. I'll actually be unstoppable in it when I'm healthy. I would like to dedicate half of this to cold water, 25% to my therapist and 25% to Sertraline. If you try this, make sure to use the happiness from the shower for exercise or something. Invest it, otherwise it fades in a few min or an hour at most. Thanks for listening to my cold water praising turned rant
| 43 |
suggestions for something a bit more stimmy?
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hello! first post here.
i am currently diagnosed with mixed anxious-depressive disorder, with agoraphobic traits. i was prescribed prozac, am on 60mg now, and recently switched from lamictal to lyrica for the anxiety part.
thing is a part of my depression manifests through hypersomnia. i sleep a lot, take naps all the time, fall asleep during uni lectures and feel generally tired and without any life in me. prozac used to help with this but i'm suspecting it's the poopout phase rn.
has anyone, preferably with a similar diagnosis, tried some kind of stimulant med or at least some addon to their regimen to get more energy? i should mention i do physical activity and mental activity. it's something i've struggled with even as a kid.
| 1 |
Abilify makes me have really bad brain fog and makes me incredibly tired
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I’ve been taking it before bed but I still feel so tired during the day! And I have brain fog like what do I do it’s impairing me I can’t do so many things because of how tired I am
| 2 |
Relivion
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Relivion is non invasive machine used to prevent and relieve headaches. Clinical studies are being conducted to assess whether the machine helps with depression. I’d rather not waste 2 months of visits and MRIs and find out I was in the placebo group.
Just curious if anyone has participated in the clinical study or was advised to use Relivion off label for treatment of depression.
I have tried the vagus nerve stimulators and as far as I am concerned I get better results from humming all day than the crappy machine.
I know it’s a long shot but doesn’t hurt to ask
| 2 |
My psychiatrist told me that depression can decrease physical fitness even if I'm less sedentary. It's worst than I think.
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For a long time, I tried hard to do some jogging just to treat my depression. It always comes with difficulty and pain.
I have been on anti depressants for 14 years now.
After feeling better for some reason I don't understand, two years ago, I was able to do 60min in the morning on a empty stomach, once every 3 days. I kept this routine for about 6 months.
Then depression came back, and I was not able to keep that routine.
So even though physical activity does help, it's not a silver bullet, and depression will still make physical activity quite painful to do, not because depression makes people sedentary, but because depression affect your nervous system, which in turn, affects physical fitness.
So again, beware of people advocating self help and "just do it" mentality. Do physical activity if you can, but always slow down if it's not comfortable.
I have a acquired a bad habit of reaching a pain level to be sure I was doing enough, but it's actually a bad thing to do.
So go slow, and don't feel bad for it, and don't be afraid of people who tell otherwise.
| 40 |
TRT for depression?
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I got my bloodwork done and my test levels are a little towards the lower side, but not sure if it’s low enough to get prescription trt. My question is, has anybody here got on trt/low dose test and felt it helped your mood/energy?
| 3 |
No meds in the near future
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My meds don't work so I decided to not take them anymore.
I had 2 series of ECT as well...
Lately I've been trying ketamine without any results (beside being drunk for an hour after taking it)
Like one of my psychiatrists said 'my neurotransmitters are overstimulated from trying over 30 different meds in different doses and combinations'.
I'm a bit worried I won't sleep without mianserine but I'm not sure it helps with that at that point as well.
My liver will be shocked. I don't remember the time I didn't take any psychiatric medication.
I haven't tried MAOi yet but I don't believe they can help. Of course I don't believe at this point and in this state of mind...
I'm not functional. Too depressed to even have the energy to end it.
| 3 |
Moclobemide sides when starting? And my experience about a week in
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Hey!
Started moclobemide under a week ago (2x150 mg a day). I switched from 300 mg/d bupropion which was definitely an ok drug, it gave me energy to do stuff that in turn helped my mood. But I felt like it didn't really help my primary issue of anhedonia (I just don't have much interest or drive to do anything because nothing feels like anything) that much so I asked the Dr. for moclobemide because I don't want to use SSRIs/SNRIs or anything with sexual side effects since I have enough sexual/erectile dysfunction as it is. She wasn't really familiar with it at all but thankfully was willing to prescribe it to me.
Well last week I thought the moclobemide is doing absolutely nothing or just giving me about exactly the same amount of energy/effect as the bupropion. I did start to have this "heartburn" (I don't get any burning feeling so heartburn for me just feels like slight nausea) but that is not unheard of for me and I didn't immediately connect it to the moclobemide... But I then dramatically reduced my coffee intake and bought some pantoprazole that I occasionally (successfully) use for heartburn. Well the slight nausea has not gone anywhere or responded at all to these measures so now I'm absolutely certain it is from the moclobemide. I've thus eaten very poorly (not an issue for me usually) and lost quite a bit of weight even in under a week. Short term this is mostly a good thing because I can stand to lose quite a lot of weight and the nausea is just annoying but not too bad. I've also had some diarrhea which might be from the moclobemide OR just from eating quite little.
Other than that the only other side effect is this slight feeling of weakness in my legs. Hard to explain but kinda feels like my legs would shake easily when I do anything. But my actual leg strength seems fine based on my gym performance.
As for positive effects I initially thought its not doing much or is doing about exactly same as the bupropion. But especially the past two days have been great. Today when I woke up I felt kinda blaah (might be related to my sleep apnea, I'm waiting for a CPAP device now, I'm hoping this might be the core reason for my depression) which for me usually means the whole day is going to be like this. Took my moclobemide, did my morning routine and started feeling quite energized and good! Then later on I left for the gym and I was feeling so good with the sun shining and listening to some good music I couldn't help but smile! When driving to the gym I almost cried cause I was feeling good and hopeful cause then I really realized the medication is definitely doing something! I've also been very talkative with my friends and messaging them a lot. I also noticed I've been feeling more horny and even felt like I might have a spontaneous erection (which I NEVER have, other than morning wood rarely). Sexually bupropion didn't seem to do that much, I might have had a bit better libido. It however DID reduce my erectile function a bit which it "supposedly" doesn't do.
But anyway, I'm interested to hear other peoples experiences especially from this induction phase and the related side effects and how long did it take for them to go away? From skimming some studies seems nausea is a common side effect but the initial side effects tend to go away in a couple of weeks? Short term I'm "fine" with the nausea, it is not so bad but I need to start eating properly at some point...
Edit: Also interested if someone has ideas if there is some antiemetic or something I could ask my doctor for that I can take with the moclobemide? Not super hopeful about this, I have the vague impression they are all some antihistamines or something which tend to have other side effects like drowsiness or something which I don't want since the nausea is not too bad...
| 3 |
Persistent dissociation, thoughts on how to get better
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I’m diagnosed with bipolar, ADHD, PTSD, and in the past struggled with OCD as well. I’m relatively stable with cariprazine, venlafaxine, and lisdexamfetamine, and also take ashwagandha, omega-3s, and multivitamins. rTMS got rid of almost all of my OCD symptoms so that’s no longer really an issue.
However, I still have persistent dissociation that gets worse at times, and I can be triggered into worse depersonalisation and derealisation. But the baseline of dissociation almost never seems to go away. I’ve felt distant and detached most of the past 8 years with only moments or maximum days of feeling present with little dissociation. It’s been exhausting and I feel like I’m running out of options what to try next.
Lithium never worked for my mood swings, I continued to rapid cycle on it. Antipsychotics (olanzapine, quetiapine, aripiprazole, sulpiride, perphenazine) with the exception of cariprazine always made me feel even more dissociated and had really difficult cognitive side effects. Antidepressants (sertraline, paroxetine, clomipramine, amitriptyline, mirtazapine, mianserin, moclobemide, vortioxetine), some helped with my mood, some did nothing, but no effect on dissociation. I’ve found venlafaxine the best for my mood with least side effects. Methylphenidate seemed to make dissociation worse while lisdexamfetamine helps a bit, likely indirectly through improved concentrations and ability to manage my life. Buspirone didn’t do anything while pregabalin was helpful but I build tolerance to it quite rapidly. Oxcarbazepine, carbamazepine, and topiramate made dissociation much worse. Lamotrigine helped a bit but not enough to make up for the cognitive side effects. Ketamine helped a bit but I cannot get it where I am without doing ECT and I’m leaving ECT as the last last last choice. Psilocybin helped a lot the first few times but then I started getting bad trips always on it, also tried microdosing but that didn’t do anything. rTMS did nothing for dissociation. I’ve done CBT, EMDR, integrated, hypnosis, acceptance and commitment, and schema therapies. EMDR and schema therapies have helped a lot, but it feels like over the past 1.5 years I’ve stopped making progress. Internal family systems therapy has been helpful but my insurance does not cover it and cannot afford to pay for it, so have been studying it from self-help books. I’ve started to meditate daily (now for a couple of months) but so far have gotten limited benefit.
I’ve had extensive blood work done and everything is normal. I had an MRI and nothing seems to be wrong with my brain structurally. I go on walks every day and eat healthy these days.
I went back to university and am graduating soon with great results, have been working periodically. I have bad periods now and then but generally seem to be quite high functioning these days. On paper, I seem to be doing really well (at least compared to how it was four/five years ago). But this dissociation just makes everything feel so meaningless and I feel like watching myself go through life most of the time. I find it difficult to connect with people, seeing your surroundings, and not always being in this haze.
Has anyone found something that works for their persistent dissociation? Decided to post here and see if there was something I had not tried yet.
| 3 |
Switching from Effexor to Wellbutrin, can someone help?
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I was on 225 Effexor, I want to try Parnate, but need to get off Effexor first. I added 150 Wellbutrin, and dropped Effexor to 150. Can I go to 300 Wellbutrin?
| 1 |
I don't know how to get better
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I lift weights regularly, play sport, eat healthily, get plenty of sleep, my hormones are fine, regular exposure to animals and nature, taken every class of medication, seen 15 talk therapists (cbt & dbt), been practicing mindfulness for nearly 20 years, have routines, kind with myself, I'm rational, take pride in my possessions, I work, dress well, take of my appearance, like my appearance, like myself, no longer cut myself, don't drink/do drugs/smoke, good ethics, don't use social media etc.
The last time I saw a therapist, Jan 2022, they said "we can only offer anti-depressants and cbt, both of which you've had extensively and we don't think it's worth doing again, so all the best."
I 100% agree with their conclusion, yet this means I'm alone out there and still absolutely depressed, get panic attacks, very lonely, *endlessly* empty, suicidal every day and just fucking LOST.
Ketamine isn't available where I reside, psilocybin is illegal (yes to grow it too) and I've tried cannabis. I've dabbled with \~30 supplements and I don't think they help.
If I do some research about this, all I read is the usual generic advice of exercise, routines, talk to someone etc. which as described above is something that I do extensively/have done extensively.
This is often unbearable.
| 10 |
Is it bad
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Is it bad that I’m almost 25 and have never lived away from home and I’m a guy… I’ve struggled a lot with my mental health and getting going
| 3 |
What to check in the bloodwork is recommended?
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What are recommendations to check in the bloodwork during long term SSRIs and Antipsychotic usage? Does those lead in any deficiencies?
F36, going to my PCP due to extreme fatigue and low energy issues (definitely checking iron and hormonal levels). Just want to make sure we wont miss anything.
Thanks!
| 4 |
Sleep/lack of sleep
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I have problems sleeping i have tried hydroxyzine(mega hangover feel stupid and like im under its influence the next day), clonidine (diarhea constantly peeing plus doesnt really work and makes me dizzy). Has anyone found a sleep med that works?
| 1 |
Psilocybin and treatment resistant depression
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I suffer from treatment resistant depression. I have been on more than a dozen antidepressants (tried every class of medication) in the last 3 years and none of them have provided relief. I decided to go off my meds recently, wait several weeks for my meds to clear from my system, and try psilocybin. I took 6.5g (close to a heroic dose) but didn't have a psychedelic experience at all, just tiredness and upset stomach. I had similar experiences trying psilocybin in the past. Should I try a larger dose or come to terms with the fact that psilocybin, like antidepressants, just don't work on me? Is there some explanation for this?
| 8 |
Starving myself seems to ease depression?
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Not sure why but it works!
| 8 |
Has anyone experienced longer effectiveness with a different antidepressant without "poop-out"?
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Has anyone switched to a different antidepressant and felt like it worked better for a longer period of time without "poop-out" compared to their previous medication?
| 2 |
What three years of depression can do to you.
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Before and current day
| 105 |
Seeking Advice: No Effects on Anafranil (Clomipramine) 37.5mg after 16 Days - Should I Wait or Increase the Dose?
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Hey, Reddit community!
I'm hoping to get some guidance regarding my experience with Anafranil (clomipramine). I've been taking a daily dose of 37.5mg for the past 16 days, but unfortunately, I haven't noticed any significant effects yet. I'm a bit torn between waiting it out or considering upping the dosage, and I'd love to hear your thoughts and experiences.
To provide some context, I started taking Anafranil to address certain mental health concerns. I had high hopes for the medication based on positive reviews and recommendations from others, but so far, I haven't experienced any noticeable changes in my mood or overall well-being.
I understand that antidepressants and other psychiatric medications can take time to build up in the system and produce noticeable effects. However, I'm beginning to wonder if 16 days is sufficient to determine whether Anafranil is working for me. Some people say it took them weeks or even months to feel the full benefits, while others noticed improvements sooner.
Should I give Anafranil more time to work its magic, or is it worth discussing a potential dosage increase with my doctor? I'm aware that altering medication dosage should only be done under medical supervision, but I'm genuinely curious about your experiences and advice in similar situations.
Of course, I plan to consult my doctor as well, but hearing from those who have been through similar experiences could provide valuable insights and help me make a more informed decision.
So, if you've taken Anafranil or any other medication similar to it, I would greatly appreciate hearing about your experiences. Did you notice any changes within the first few weeks, or did it take longer for the effects to manifest? Have you ever needed a dosage adjustment to achieve the desired results? Any tips or suggestions would be highly appreciated.
Thank you in advance for taking the time to read my post and share your thoughts. Your support means a lot, and I'm looking forward to hearing from you!
| 3 |
What's your relationship with Caffeine like?
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Only time I truly feel happy and optimism is when I take caffeine or one of those 5 hours shots. When that stuff wears off I am back to being depressed and numb.
| 8 |
I was off my Auvelity for a few days and it may have triggered a hypomanic episode
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This has become one of the most bizarrely...good?...periods of my life thus far.
I am "officially" diagnosed with "Recurrent major depression resistant to treatment" and I've been on various antidepressants constantly for about 15 years. About 6 months ago I started Auvelity. Started feeling pretty good. No discernible side effects.
In May, my pharmacy was having trouble restocking the Auvelity. I don't know why. I was off my Auvelity for like 3 days until they finally got their shipment or whatever. And by the third day I felt...different.
I felt smarter. More perceptive. Confident. Emotional. Motivated. I felt good in a way I've never felt at any other time in my adult life. It's like a veil was lifted from my eyes. It's like I'm a completely different person.
I knew this was just a reaction to the sudden discontinuation and then resumption of the drug I had been taking for months, but I still made the personal decision to reduce my daily dose of Auvelity from 2 pills to 1. I saw my doc and they supported my decision, but still informed me I was almost certainly in a hypomanic state.
It's been a month since I lowered my dosage and I still feel (on average) pretty great. In the back of my mind I worry that I'm in a *Flowers for Algernon*-type situation: as the hypomania wears off, the depression is going to come back with a vengeance.
I will have received a taste of what it feels like to be "normal", only to be dragged sloooowly back into the abyss from whence I came.
Has anyone here experienced anything like this? Should I be planning around losing all this wonderful motivation and energy? I feel like I could live the rest of my life this way.
| 3 |
tapering off zoloft (75 mg)
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Hey, i'm looking for some people's experiences with tapering off zoloft (NOT cold turkey, thank you though). I've been on 75 mg for about 3 years. Never wanted to up my dose to 100 or onward as psychiatrist was suggesting for PTSD, as I really didn't like having no libido. So here I am. It's been about? Two months now? Maybe one and a half? That I've been tapering off 15 mg per week. Initially, had awful brain zaps, panic, couldn't sleep. That was just the first lowering of just 15 mg. After each subsequent lowering, I have some insomnia (usually lasts 2-3 days, little to no sleep) but then I can sleep alright. I'll also have random weeping spells, panic spells, et cetera. Some of the weeping feels unending and gutted, some of it feels almost okay, hesitant to say cleansing (had cried a lot less on Zoloft/difficult to cry). Now I'm down to 25 mg and I am feeling so weird. Tingling in the back of my neck/head, headaches, confusion, really slowed cognitive function (I couldn't remember the order of the seasons, earlier - or I'll be doing something and then completely forget). It's really scary. Is this a part of going off Zoloft, and how long should this last? My mood has otherwise been alright. I've got more depressive symptoms and I'm definitely more anxious, but I can deal with that and make lifestyle changes once these physical symptoms clear up. I'm just scared they won't clear up. Especially the cognitive part!
| 1 |
Is it worth it for me to try TMS Therapy?
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For the last 3 years I've been dealing with the following symptoms:
1) Decreased sex drive. I no longer have an urge to have sex. I can no longer feel sexual attraction, sexual desire, sexual thoughts, etc.
2) Emotional Blunting/Anhedonia. My emotions have become severely blunted. I can't laugh like I used to. I can't really feel pleasure or joy. I can't feel adrenaline anymore and I no longer get the sensation of my heart beating out of my chest when I am in stressful situations.
3) Decreased appetite. I no longer feel hungry or have a desire to eat.
4) Brain Fog.
5) Muscle Tension/Aches.
6) Erectile Dysfunction.
These symptoms all began after an episode of sympathetic overdrive. I was dealing with intense and chronic stress, depression, and anxiety. My body and brain was constantly in fight or flight mode then all of a sudden everything just seemed to shut down and I've been left with these symptoms. It's like my body and brain couldn't take it anymore and it just shut down.
I've been trying to recover. I've been trying to reverse my symptoms. However I haven't really been successful. I've had my Hormones checked. I've had an MRI of my Brain and Pituitary. Tests come back normal and can't really pinpoint what is causing my symptoms.
At this point I have no diagnosis. Perhaps I am dealing with a form of Major Depression. However can Major Depression cause all of the symptoms I'm having?
I haven't been responding to conventional treatments so I am looking to try TMS Therapy as a next step. What do you guys think?
| 3 |
Details about lamotrigine withdrawal
|
I thought I would provide an update on my tapering experience with regards to water retention, since I would have liked to know about this when I started.
I’ve been tapering off of lamotrigine since end of January 2023, after being on it for one year for bipolar 2, during which it (together with coming off Prozac) totally ruined my life. Anyway, I was on 400mg when I started tapering and I’ve noticed that when I lower the morning dose I get really bad withdrawal — water retention, weight gain, sugar cravings, sadness, anger, sometimes horniness (!), and teariness (ie sudden need to cry). Sometimes also sore boobs and a premature period (ie after just 11 days!). It’s like bad PMS, which makes sense since apparently lamotrigine does a number on your hormones. But this doesn’t seem to happen when I lower the evening dose. And I’m tapering very slowly, by 25mg increments every two to four weeks, apart from the time before this one, when I lowered the evening dose by 150mg, which took me down to 150mg in the morning and 100mg in the evening. I was pretty much fine when I did this, just as I was pretty much fine the two times before that that I lowered the evening dose. This time, I reduced 25mg from the morning (ie from 150mg to 125mg) and I’m already feeling the usual withdrawal effects. It is so bizarre! I kind of wonder if it has to do with some kind of interaction with the Prozac 20mg, which I take in the morning at the same time as the morning dose of lamotrigine.
Would be great to know if this has happened to other people, and I also hope that what I’ve described helps someone else wondering what the hell withdrawing from this med is doing to their body!
| 1 |
Based off what you’ve seen recommended on this community, what anti depressants seem to be the most commonly mentioned?
| null | 1 |
Reddit is killing third-party applications (and itself). Read more in the comments.
| null | 17 |
Lack of motivation and loss of interest in everything
|
That's my only symptoms and nothing seems to help. It started back in my childhood and it just gets worse and worse.
I tried sertraline, duloxetine, escitalopram, venlafaxine. No response at all.
Now I take pregabalin, moclobemide and started seroquel few days ago. Pregabalin helps a little bit with pain and this feeling of heaviness in my body. Seroquel seems to help with panic attacks. No improvement on my lack of motvation and loss of interest though.
| 7 |
How has your experience been with levomilnacipran?
| null | 9 |
Can a diet change/adding supplements stop a medication from working?
|
My doctor had me drastically change my diet and added about 4 or so dietary supplements, and since that day, it feels like my mirtazapine stopped working completely. That medication caused my depression to go away, but gave me intense anxiety that I was in the process of going to a psychiatrist for, but since my diet change, I went back to unbearable depression and my anxiety went back to normal levels. Is that common?
| 2 |
Regimen Advice For Treatment Resistant Depression
|
My doctor advised Effexor 150mg, Wellbutrin 150mg, Divalproex Sodium 500mg, Anafranil 25mg (for premature ejaculation) and Risperidone 2mg for my bipolar disorder, aggression and treatment resistant depression. I'm afraid to start. Shall I give these medicine a try? Advice please
| 3 |
Any issues with supplementing Taurine while taking Auvelity?
| null | 1 |
Tackling the lethargy caused by anti depressants by supplementing with another substance.
|
Apparently, modafinil is a suggested substance for the task.
What about bupropion?
| 2 |
Rexulti makes me feel drunk!
|
I've been on Zoloft for yearsssss. I went off when my psych thought I had Bipolar II but I've since been put back on Zoloft (since 2017) because it's been so successful for me. About every 5 years though, when I go off of it to try something else because it stops working at it's full potential. Well this time, new psych doctor added Rexulti. She started me on 0.5mg for a month, then increased it to 1mg. I was hesitant because this is an antipsychotic, but she explained it's used at lower doses for depression and anxiety and often used like Abilify to supplement anti-depressants like my Zoloft. My anxiety is worse than my depression; it always has been. I tend to panic instead of the typical depression symptoms, but I'm also diagnosed with ADHD and medicated for that. It's all a cluster fuck and after 21 years of "managing" my mental health, sometimes it all just causes more anxiety trying to figure out what works with what and why I can't just find a good mix that lasts for a while and doesn't make me become immune.
Back to the point of this post - after being on Rexulti about 6 weeks now, I've noticed that it's making me feel drunk! Almost like I just woke up from anesthesia! I feel more tired than I have in my entire life, my body feels weak and I'm very groggy and kind of disoriented! I went to my PCP to check my blood levels just to make sure it wasn't something physical and sure enough, my Vitamin D level was "chronically low" according to her. She prescribed a Vitydiate D3 5,000UI (not sure about spelling) and I took the first one last Saturday (this is the one you take once per week). I didn't take my Rexulti today because it seemed to make me a bit more dizzy than normal yesterday and just generally uncomfortable/uneasy feeling. I'm just tired of not feeling truly relaxed, EVER.
There's also a lot of changes happening in my life - I'm going through some financial difficulties and may have to move, and I'm 2 months into a new job that I am NOT stimulated enough at and overqualified for, sometimes it feels like watching paint dry-it's so damn boring and unfulfilling and I'm NOT used to that at work....so that could be a factor as well.
Has anyone had weird Rexulti side effects like this or am I just paranoid and it's just my Vitamin D deficiency? Help!!
| 1 |
How to combat the strong sedation effect of maprotiline?
|
Ive just started taking it 25 mg at night. It does wonders for my anxiety, but the sedation effect is super strong and makes me drowsy even after 12 hours of sleep.
Any suggestions how to overcome the sedating effect?
| 5 |
I’m so tired
|
Hi.
I’ve been trying to figure out my depression for the last 5 years. Like really trying to figure it out. I started with mindfulness meditation 20 minutes a day for like a year and a half. Then went on a plant based diet for a year and a half. Then I added exercise to the mix. I experimented with dozens of supplements and vitamins, scouring Google scholar and examine (back when it didn’t suck). Nothing worked. Or it worked for a while but then it all got bad again.
My loved ones have asked me “what do you want? What does feeling better look like to you?”
I just want to not feel like I’m drowning.
About a year ago I started trying different medications. I’ve tried everything but the MAOI’s and the tricyclics. I have developed this manic urge to feel better. I need to find the thing that pulls me out of this.
I don’t know if I will ever get it right.
Edit: I’m trying strattera and my head is finally clear. I think I was on the wrong track with only trying to treat depression when I should have been trying to address my focus issues too. I hope this helps me. Don’t give up hope.
| 22 |
How long between bupropion and MAOI?
|
Hey!
Been on bupropion (300 mg a day) for about a year now and I've mostly liked it. It does give me this baseline energy that makes it easier to do stuff that in itself makes me feel better. It does have a negative effect on my quality of sleep (I sweat a lot and toss and turn and wake up often) but that hasn't been too bad. However I feel like it doesn't really directly help my anhedonia (my main depression symptom) that much so I suggested my doctor that I'd like to try out moclobemide to see if it feels any better. She said sure and now I have a prescription for that.
However bupropion and MAOIs have cross-interactions and the doc didn't really say how long should I wait between the meds when swapping, other than don't take them the same day. How long do you think I should wait? I didn't take my bupropion today since I was sort of expecting this so it has been about 27 hours since I took any bupropion (not from the US so different brand names but I believe the ones I have are similar/same as the "XL" versions). I'm naturally excited to try it out as soon as possible but don't want a hypertensive crisis or something...
| 1 |
Taking Wellbutrin XL at night was a game changer.
|
I've been taking Wellbutrin XL (150mg) and Lexapro (15mg) for well over a year. Added the Wellbutrin because Lexapro was a lifesaver for my anxiety but it made me positively exhausted - like I needed 10-12 hours of sleep to not feel like a zombie. The Wellbutrin absolutely helped, but it wasn't perfect.
The biggest issue I noticed was getting out of bed in the morning and getting my day started. I could snooze my alarm a dozen times, then lay in bed on my phone for hours not wanting to get moving, and I would consume more caffeine than anyone ought to when I did get up.
I read somewhere, I believe in here, that Wellbutrin XL peaks in the blood serum about 7 hours after taking it - i.e. roughly after a full night's sleep. I swapped to taking my meds right before bed (literally keep them on my nightstand) and it has done a 180 on my exhaustion. I've actually gotten up on weekends because I was eager to do anything, rather than laying around. I'm also not getting the 3-4pm slump anymore, which used to be so bad I had to make sure not to drive during that time because I'd be drowsy. I've been doing this for maybe three weeks, and haven't noticed any issues with my sleep as a result, if anything it's let me keep a more consistent schedule and get sleepy at bed time.
| 24 |
So this simple combination seems to have turned my life around
|
I was originally taking an antipsychotic, a mood stabiliser and bupropion as anti depressant.
I have a tendency of not being able to forget the past. It replays in my mind countless times. It depressed me and I felt frustrated.
Upon some discussion the doctor wrote me Deanxit and vilazodone.
Deanxit is flupenxitol and some TCA (melitracen).
Within a month I felt like I have moved on from my past and stopped having thoughts about it completely.
I am not 100% sure, but my guess is that the TCA and vilazodone have done the magic by raising the serotonin. Flupenxitol Increases the dopamine and works as an anxiolytic but I doubt it had any major contribution in helping me move on.
| 7 |
does anyone have any experience with mirtazapine
| null | 1 |
Maybe i have some improvement
|
A week ago my pdoc upped Bupropion XL dosage from 150mg i was taking since 6 months to 300mg, first 3 days were horrible, now it's been 2 days i felt a relief kinda, i'm wired but empty, i feel tense sometimes but i walk more i have will to do things, i get bored at home, i can't eat, i don't enjoy nicotine anymore, but i will say this is 100times better than how i was 1 week ago, the problem is i have this weird throat and chest anxiety, also my social anxiety cameback but not depression, weird...
I hope it's not honeymoon from upping dosage, i don't even have depersonalization and derealization anymore, i feel really empty is a weird feeling...
I remember the honeymoon when i first started, i literally felt like it was a new life, i was enthusiast, and then i fell back in the hole with dpdr and suicidal thoughts sleeping 13 hours a day... So i really hope it will work this time, pray for me lol.
| 4 |
Does anyone relate
|
Hello, I’ve been really struggling with my self esteem and mental state lately. I’m 24, living at home and in community college. Ive never moved out either… is this bad? I’ve truly struggled getting going in life. I can’t seem to find anything at all that interests me. I have probably too much free time. I rarely workout and don’t have hobbies. I just want to know I’m not alone. My family always tries to tell me I need to get involved in things and get passionate about something to find happiness and I just feel like I’ve wasted years and I feel so shitty about myself. Am I a fucking loser?
| 1 |
(really) heightened anxiety onboarding venlafaxine (efexor)
|
Hi, hope you are well
So I (40M) am doing 30mg Remeron and 75mg venlafaxine ER for 16 days and it has been hell since day 3. Using benzos to cope.
Before, I tried (for 8-10 weeks each) Pristiq, Zoloft + Wellbutrin and trintellix + rexulti -- all to no avail
I am going through resistant MDD, GAD and PTSD
I had severe anxiety boarding all of these medications, but it is just ridiculous now. incapacitating. bedridden
| 2 |
Question about Armodafinil timing
|
Hi,
My provider recently prescribed armodafinil to help with energy and motivation. Not sure if I'm understand what to expect with this med.
It seems to work for many folks within a few hours. Contrarily, I've also read that it takes a week or longer to get past the side effects and really begin working well.
Although armodafinil isn't an AD, how close is it to the timing of say, an SSRI, to be effective?
Is there any additional benefit from continual use of armo, as opposed to taking it only as needed?
| 1 |
Looking For friends
|
Hi !! I am Vasu 23M... I am looking for some Male/Female friends and need someone to talk to .... I am pretty friendly guy, and interested in talking about travel, movies, Anime, music, books and foody stuff. I am currently pursuing MERN stack Development ..... I have been told that I am a good listener. So, if you wanna talk about something or anything, I am all ears. Let's chat and get to know each other if you are interested.😊😊😊
| 0 |
How long can you sustain a tramadol habit ?
|
Tramadol seems to be a god send for my depression and anxiety. I know it has a bad reputation because it is also a weak opiate. For some reason it is also a serotonin releaser.
Anyway, for those who have been on it long term.
Given that you have a lot of self control and that you will stick to your dose schedule, how long can you sustain the habit while keeping the benefit ? No wonder it’s the highest rated medicine for anxiety and depression on drugs.com
| 7 |
Has anyone had depression for many many years and then gotten better?
|
What was it that finally helped you?
| 24 |
Joining IOP program, if I am diagnosed with bipolar disorder are antipsychotics and Lamictal my only option? :/
|
Hi, my therapist said I need to join an IOP program because she is concerned about me and I need a higher level of care.
Now I do not think I have bipolar disorder, however there is definitely a small chance that when I see a psychiatrist at the IOP program they will *think* that I do.
Despite not believing I have it, I am desperate to get better so I don’t really care what the “diagnosis” they give is, I am willing to try a lot to get better. To me labels don’t really matter much.
I took an antipsychotic 5 years ago and developed facial tics, thus, I am not willing to try other antipsychotics.
I took Lamictal last year and it did not help, so I doubt this will be an option
Currently take Viibryd and Welbutrin for the last 5 months - barely any sexual side effects
though they aren’t helping much and I am still having some mood issues. I see a nurse practitioner, not a psychiatrist (not sure if relevant).
—-
I am extremely hesitant to try any medication that will affect my sexual abilities or possibly induce more tics, which from my understanding is practically all bipolar medications.
Are these the only options in the off chance I am dignised with bipolar disorder? I need to get better but **I got facial tics from an antipsychotic before** and thus am not willing to try other antipsychotics…
| 6 |
does anyone's depression cause brain fog after eating
|
I've had depression/anxiety issues for 2-3 years now, 2 weeks ago, I think I experienced a stressor. Now I have very shifting symptoms from depression to anxiety. I dont really feel brain fog unless I eat/drink, and somethings are worse than others. Think milk and eggs give me the most brain fog, especially eggs. This only started 2 weeks ago.
| 6 |
Anyone received racemic ketamine nasal spray from a compounding pharmacy?
|
The reason for my post is to attempt to find anyone who has used a specialty compounding pharmacy to fill a prescription from a psychiatrist for racemic ketamine nasal spray. I ask, because from what I have read, this seems to be potential avenue to obtain ketamine for treatement resistant depression.
For some background, I am highly treatment resistant and a genesight test confirmed that I am indeed a poor metabolizer of nearly all conventionalantidepressants from their respective drug classes. A few years ago, I was in such a desperate condition that I sought IV infusions of ketamine from a clinic which provided a 40 minute slow drip IV twice per week for three weeks to treat my major depressive disorder. The starting dose for infusions is .5 mg/kg, however, my body seems to have a naturally high tolerance for dissociatives and so this was quickly titrated up to 1.2 mg/kg, at which point I was finally able to have a full dissociative experience and gain the mood benefits that followed.
Unfortunately, these infusions are not covered by insurance and simply are financially unsustainable (costing between 400-600 dollars per session). Flash forward to present day and my mental health has really been suffering again, however, I now have different insurance and discovered that the administration of Spravato by a REMS clinic would be covered. At first I was excited because this meant that I could be treated with s-ketamine nasal spray without the burden of cost.
According to the Spravato protocol, only 56 or 84mg sprays can be provided. The 56mg is used initially to ensure a normal response and then the dosage is increased to 84mg which is administered twice per week. There is no dosage adjustment for weight, for individual metabolism, or individual response. The REMS program is so tightly controlled that getting Spravato approved and then supplied to a certified clinic by a certified pharmacy is simply a logistical nightmare. But I digress.
Personally, at 84 I can very barely feel anything, and am not blinded to the experience, so I am acutely aware that I am not being provided a sufficient dosage. When considering my past response and the above average required dosage, and when you also apply the seemingly basic logic that individual metabolism and reaction to the drug will vary, it seems absurd to me that this is the ONLY dose that clinicians can use of Spravato to treat patients. The protocols, method of administration, and optimal dosing strategy for treating MDD with Ketamine is far from reached a consensus in academic and clinical communities. And although the science is still out, there is at least some evidence suggesting that antidepressant effects correlate with the strength of the experiential dissociation, potentially because this indicates that levels in the brain are sufficient to fully antagonize NMDA receptors, along with whatever other antidepressant mechanisms are simultaneously occuring.
So now this brings me to my question about racemic nasal spray from a compounding pharmacy. From my understanding, a psychiatrist can prescribe it and a specialty pharmacy can compound it. From one specific website I found offering this, the prices were reasonable. Additionally, since it is racemic it is not controlled by a REMS program, can be taken at home, and there is more room for collaboratively determining the dosage and dosing schedule with the prescribing doctor.
If there is anyone out there with experience going through this process who may be able to share some insight, tips, or resources, it would be greatly appreciated. Thankfully I have an amazing psychiatrist who is always willing to try anything that might work and was the one to refer to me the Spravato clinic. I'm not sure if he is aware of the possibility to prescribe a racemic spray, but if it is possible, I'm sure he would be willing to pursue the avenue as long as we can locate a compounding pharmacy to supply it.
Thanks in advance for any input.
| 1 |
MAOI back to SSRI
|
Anyone ever done this? I’m considering it.
| 2 |
anyone else tried this combo?
|
currently prescribed
- 200mg zolof for mdd
- 70mg vyvanse and
- 40mg dexamphetamine for adhd
- 15mg valium and
- 50mg seroquel
both to use as needed for panic attacks and sleep
tried lots of various regimes (effexor, lamictal, lexapro, mirtazipine, propranolol, catapres etc) and honestly think this latest effort might be it before ECG or some other type of treatment.
would appreciate any views or anecdotes if you’ve had any similar experiences :)
| 1 |
actually properly processing emotions just sort of stops rumination?
|
it's really strange. even if i try really hard, i physically cannot ruminate over the thing that i grieved. it's like my brain is like, "no, that's boring. i don't care about that anymore, shut up"
anyone else experience this? it's just crazy. it seems like such a huge problem 4-5 days ago. but crying and being depressed over it for days made me just sort of stop caring about it
| 24 |
Any SSRI, SNRI out there that doesn't cause lethargy?
|
I have tried escitalopram, fluoxetine, sertraline, vilazodone. Vilazodone seemed to work best but caused lethargy.
| 2 |
I'm on 4th type of my antidepressants, feel kind of discouraged so far.
|
Escitalopram - took for 11 months. At the beginning was ok, then great(2-3months), then half year later everything started to go down and it stopped working. I think had no side effects, well almost, cuz was extremely sweating at night and lost libido for the whole time. Mentally made me feel a bit better, but not for long and consistently. Started having huge anxiety and panic attacks. Numbness, emotionless and nightmares also followed.
Venlafaxin - took for 4 months. Mentally at the beginning it was horrendous(suicidal, wanted to harm myself), after few months it finally kicked in and i felt so peaceful and it was quiet in my head, calm, didn't feel depressed almost, no anxiety in my chest choking me, no panic attacks. Was actually quiet happy. But then side effects also kicked, and it was too much to endure it, it got only worse day by day - extreme nausea every day, headaches that turned into weekly migraines, extreme fast weight gain without eating much even, was forgetful, brain felt foggy, felt lost, no libido, night sweats, extremely numb and empty feeling. Dropped it, i felt miserable. Side effects overtook the good side of this drug.
Bupropion - 2 months. Nothing to say much, no side effects. It actually got rid of all the side effects i had from previous depressants, for that i alone felt so happy. But also didn't work for me at all mentally this time. Didn't help my anxiety, depression, non stop overthinking, it did absolutely nothing. It made everything actually 10x worse, even after upping the dose to 300mg. Extremely angry, irritated, violent, constantly pissed off like a bee, depressive, numb, empty, no energy or desire for anything at all, total anhedonia, just everything was bad. It was horrible, finally stopped it, don't wanna see that ever again and go through that especially, was the worst so far.
Tianeurax - and now today i was prescribed this, and im extremely scared because of the reviews i keep seeing.
What should i expect? Are all these opiod stuff i keep seeing are true? Any major side effects? What should i expect? To be honest this is so far, that I'm most scared to start taking.
I will be taking 12.5mg 3x a day.
| 10 |
Worsening depression despite SSRI and common nootropics stacked
|
Hello,
I’m a 29yo Male with ADHD, PTSD and chronic insomnia. It wasn’t until maybe the last few years I started feeling depression and anxiety, and it’s been progressively getting worse as I get older. I’ve yet to be diagnosed with depression, nor have I had my hormones tested (recently). I do plan to have my testosterone looked at, since I have used PEDs in the past. However, the depression and anxiety have come on several years since I’ve taken any sort of hormone altering drugs, and there are other things indicating it is in fact NOT low-t. The symptoms have come on pretty rapidly over the last 2 years and each month seems harder than the last. I’m in general very active and motivated, but I’ve hit a point where I’m uninterested in the gym and having difficulty doing the bare minimum in life. I’ve tried experimenting with different supplements, some work briefly and some make things worse. I’m interested to see what maybe some of you might think I should try supplement wise before diving into trial and error with perceptions. I’m currently taking:
Vyvanse (ADHD)
Trazodone (insomnia and depression)
Ashwaganda
Fish oil
Ginseng
Ginkgo
Lions mane
Creatine
I’ve tried l-theanine in the past and it honestly made me feel a lot worse. Gave me anxiety and made concentrating near impossible. I tried several brands to see if one reacted better but no luck. Ashwaganda had me feeling really great for maybe 2-3 weeks when I was approaching 2 months of daily use, this has since worn off and I feel back to my base level. I do not take Vyvanse daily, and I’m taking a very low dose for my weight and for how long I’ve been taking it. I take Vyvanse on days that I know I will need to be concentrating more or when brain fog has totally blocked me from being human. I take trazodone at night, and it’s helped my sleep immensely. I was averaging around 2-4 hours a night for most my life and have been averaging 6-7 since being prescribed almost a year ago. I did notice that my depression has worsened since taking this, but I find it hard to believe that better sleep and something often used to treat depression would be the culprit (also considering nights that I can’t sleep, I feel even worse). Fish oil has zero effect on mood. Ginseng I’ve taken for years since I do not drink coffee or tea, it’s a more relaxed boost of energy/focus with a subtle boost to libido. No negative sides from ginseng. Ginkgo has no noticeable effects on me, just is often included in ginseng matrix’s. Lions mane helps with my ADHD, and some days I notice more of a cognitive boost than others. It took a while before I noticed any effects from it, but I am surprised at the clarity I can achieve without Vyvanse from just Ashwaganda and lions mane (some days, as I mentioned the effects vary from day to day). I take creatine because I’m a lifter, but I do notice a slight cognitive boost as well. I’ve seen people recommend saffron for depression, but what else? I’m trying to avoid taking everything under the sun, so I’m hoping there are people with similar situations who have found something notable. Is saffron usually stacked with something else? Is there something like say Alpha GPC that would make my current supplements/medications more effective? Happy to share any additional info needed to assess and will update as I find out more on my own end with doctors and testing.
| 8 |
NAC and an SSRI(Lexapro)
|
Hi all. I'm considering adding NAC to my regimen for a few weeks to see if I would benefit. I don't believe there is any significant interactions between an NAC and an SSRI medication, but I would love to hear from a few folks that have used NAC while taking an SSRI.
| 2 |
Does a stimulant that doesn't also effect the body exist?
|
Most CNS stimulants (ADHD meds etc) stimulate both the mind *and* the body.
The latter manifests as:
* Increased heart rate
* Increased BP
* Increased muscle tension
Are there any stimulant(s) out there that are psychologically "active" (in the sense of alleviating ADHD symptoms) but physically basically inert (or as "inert" as they can possibly be)?
TIA!
| 4 |
A comprehensive review and meta-analysis of neurological side effects related to second-generation antidepressants in individuals with major depressive disorder
| null | 1 |
Summer depression
|
I have this horrible feeling all the time that nobody likes me … I feel like I get on Snapchat and see everyone else having so much fun at the lake or with friends and I just feel so lonely. Anyone else feel like nobody reaches out? Maybe just me
| 11 |
THIS belief is what has actually helped me heal.
|
I went through the darkest, deepest desperation from about 2-7 months, it was so Acute. You know when you physically stub your toe and the pain is so heightened and acute for about 15 seconds? Then you also know what it’s like to have these UNREAL emotional moments that are completely unbearable but they also tend to last for only 1-2 min max. I lived in that acuteness for weeks at a time. I remember calling both of my parents telling them that I’m not sure how much longer I can endure and hang on.
It was so pathetic, I’d just wail and cry and felt utterly hopeless until one day I literally yelled out to God “THIS CANT BE HOW ANYONES EXPECTED TO LIVE THROUGH- HELP ME”
And the one Monday morning I woke up and felt conscious in my body and my mind. I was no longer at the complete mercy of my mood, intrusive thoughts, or feelings. It was like my life during depression was a video game that I was existing in and had no agency, but then once it lifted a little bit then all of a sudden I was able to function better.
The key has been for me is to remind myself that I have a choice in every single brutal moment. When I’m overwhelmed with grief about the past or the future, I tell myself, “you can cry and drop into dark feelings about this and it would be completely valid, but what life do you want? Your grief is justified, but do you want to live a life where you were simply at the mercy of your circumstances?” The answer is usually no. So then comes the CHOICE. I see the reality of my situation, but what if I chose to believe that I deserve to experience joy? Doesn’t mean I will feel it right then and there, but it forced my brain not to accept the label of “sad”. It forces me to take the moment captive and CHOOSE my response. I could cry for 3 hours and hate myself, or I can push through the physical pain, and the emotional pain of inadequacy, and say out loud “ I AM JOYFUL. I have many friends. I have a life if influence. The burning pain I’m feeling right now is directly burning a path for me to walk through to the other side of the field. I’m not religious, but the imagery of Moses being courageous and probably terrified, depressed, hopeless, inadequate as a leader but having to uphold the responsibilities of thousand of people he just lead away from their homes sticks with me. He had the enemy right behind him and an ocean in front of him. He was royally fucked and probably had every reason to accept that he was a failure. But then he called out to the creator (God, Buddha, self, universe, nature, love -whatever) asking for help, then made a fool of himself while thousands watched by walking up to the waters edge, and he put his staff into the water by faith alone. THE FUCKING SEA OPENED UP. Everyday, people are creating impossible pathways from the deepest despair. I have major depressive disorder and I hate what it’s stolen from my life, but I am now choosing to stop believing that it’s not forging a path through. We have wisdom and knowledge and peace that the happy-go-lucky people never will. And truth is just as important as grace.
Just like you said, I can’t end my life to then traumatize my family and friends and never accomplish my purpose- I can’t knowingly hurt those I love. So then what? It’s my choice. Nelson Mandela could’ve just gotten out of jail to simply hide from people in the bush. He had every reason to feel cheated, inadequate, worthless, lost. But he chose to carry on and he legitimately changed the world.
I don’t have it figured out. In fact, today I’ve been scared that I’m getting sad and am overwhelmed by circumstances and feel totally inadequate, but I’ve now just spent 20 minutes writing this out instead of just scrolling and I’m feeling better already. The choice is ours. Giving up the expectation that it’s not going to hurt one day is key, but it’s also comforting that everyday gets easier if we believe it does.
HOPE.
Hold On, Pain Ends
| 25 |
UK folks only - I'm going to try to persuade my private psychiatrist to put me on either Oral Ketamine or Buprenorphine for Treatment-Resistant Depression.
|
Foreword: it seems both these medications, for the prescription of adjunctive treatment of Depression, are 100x more difficult to acquire in the UK than the USA. Ketamine you can literally mail order in USA; Buprenorphine I've heard from several acquaintances in the USA was prescribed to them no-problem by their own psychiatrist for off-label augmentation of Depression treatment.
\----
I have been fighting severe depression for over 15 years. Despairingly, I'm almost at the end of the road in terms of trying literally EVERY SINGLE TREATMENT OPTION KNOWN TO MAN. The only medication I have yet to try are the oldschool Irreversible MAOIs - but I'd prefer to leave these as an absolute last resort, given the huge risks if I don't watch my diet or whatever medications I may take in the future.
Before taking this absolute final solution, I'd first like to try my hardest to go on a trial of Buprenorphine or Ketamine, the only 2 drugs I've never tried that have shown to be very powerful solutions for otherwise Treatment-Resistant Depression.
Over the last 10 years, heaps of studies have shown Buprenorphine to be a very promising augmenting drug for Treatment-Resistant Depression. Several of my colleagues in the USA have even said it was "the one thing that saved their life".
As for Ketamine, there have been even more studies done showing its efficacy in treating Treatment-Resistant Depression (I'd estimate 4x as many studies compared to Buprenorphine).
\-----
Now here are the problems that I, as a UK resident, am facing in being able to get my private psychiatrist to legally prescribe me either of these controlled substances:
​
1. BUPRENORPHINE
Although it is relatively cheap, can be used at home, and MUCH easier to get ahold of than Ketamine (at least in UK), here's the problem: there is next to ZERO data in UK guidelines or publications advocating the use of Buprenorphine in the adjunctive treatment of Depression at all, in spite of there being countless publications in the USA that clearly indicate its efficacy. So it's gonna be hard for my psychiatrist to legally justify prescribing this, per UK guidelines.
​
2) KETAMINE
Ketamine - at present, there are 2 ways only to be administered Ketamine for Depression in UK. First one is the Esketamine nasal spray "Spravato" - a simple 4-week course of this alone would cost just under £2000. Madness. So that's out of the question. The second way is to attend one of a handful of specialist clinics (eg. Oxfordshire NHS Trust) where you have to be individually referred, even through your own private psychiatrist, whereby they start by giving you several administrations of IV Ketamine, before eventually moving on to maintenance with Oral Ketamine (given as an oral solution liquid).
\-> although the 2nd way of getting Ketamine in the UK is a damn sight more affordable than the Nasal Spray option, it is nonetheless still very expensive, and very time consuming (you have to travel all the way to their hospital to have each treatment administered, plus the wait time can be as long as 3 months).
Here's my thoughts: there are a load of official NHS documents proving that Oral Ketamine can in fact be prescribed to a patient from the very beginning (although for purposes NOT related to Depression). In conjunction with this, I have compiled a large list of studies which show that Oral Ketamine alone, in doses not exceeding 100mg, have been shown to be effective as a form of Ketamine administration for the specific treatment of Depression. Problem is: finding a way to get my psychiatrist to skip straight to prescribing me Oral Ketamine, without having to go through all the trouble of being referred to a specialist clinic and having to undergo a load of IV treatments first.
\------
Honestly, in your opinion, what are my chances?
​
| 2 |
Success Stories
|
Anyone have any real success stories where their depression has lifted and they see things clearly for a time.
| 6 |
My Stress induced Anhedonia/Numbness progress so far
|
I think it was triggered most likely by a lot of chronic stress during my 2021 covid year of school. It was hard for me to do e-learning and I procrastinated a lot. I didn’t really take care of my mental health and basically the build up of stress over time is what I think did it. I was also taking doxycycline antibiotics for acne for probably too long around this time, for about 4 months, a month break, then another month, but I don't know if that had anything to do with it or not. But I have been taking probiotics for a while.
So far I’ve been mainly dealing with this naturally, and have only tried a few supplements. Daily exercise (weights and running) and especially 15 mins of meditation have helped a lot with the stress/anxiety/ocd side of things. When my mental health was worse those things stuck out much more and were a lot more of a problem, now they are all much better. Overall my mental health is a lot better but I still feel “numb,” but not the super annoying physical numbness I have been feeling before. During the school year I was also seeing a therapist/counselor at my college, which also helped. Last year in the summer I was getting bad brain fog like every few days, now I only get it maybe like once a month, I feel a lot more clear headed now. But it is still hard to enjoy things again.
Every once in a while there will be a time when I get slightly excited/hyped about something and that will overall make me feel a lot better (still very far from normal though), and will cause other aspects of my life to improve as well, like sense of attraction. I will in general feel closer to normal, and quite a bit better than the status quo. But usually something will come up like stress or work or something that doesn’t let me really help the feeling grow. I’m really gonna try to do more enjoyable things that I have done before consistently and really try to get back into things I’ve loved doing. I have been trying for a while now but I really need to constantly stay at it. It really does seem like I have to train myself to enjoy things again, even though the conditions that put me here have been gone for a long time. So overall my mental health seems to have improved a lot, but there is still quite a bit of work to be done. Also, I know it seems counterintuitive, but dwelling and worrying about this less has also helped, like just thinking more about normal life things more than the numbness problems. I think that really helps decrease the stress overall making me less numb. I also pretty much do things with my friends as much as I did before, which helps me not worry about it all the time.
I just wanted to put this on here to show what has been helping me so far, if anyone has gone through anything similar, and was wondering if anyone had some advice on what to do onward. I took care of my stress and anxiety problems for the most part and still am, but it's just really hard to really consistently start enjoying things again.
| 5 |
What gave you your drive back and helped with overwhelming feelings?
| null | 7 |
Can Antipsychotics Cause Mood Swings?
|
I've been trying to find the right doctor and the right meds for awhile now. I recently started Abilify and today had a pretty extreme mood swing. I don't normally have mood swings.
Granted I was triggered, so it's not like the mood swing came out of nowhere.
Thoughts? Should I continue taking this med?
| 2 |
How serious is Buspirone withdrawal?
|
Thinking about trying Buspirone for social anxiety and depression as more than 14 different meds didn‘t help me yet and I still didn‘t try the Buspirone (Buspar).
So, to anyone who has taken Busprione for anxiety or whatever, how bad was getting off of it (withdrawal)?
What symptoms did you experience as soon as you were off of it and how long did it take until you‘ve been back to normal?
| 6 |
Do we need to bear insane anxiety for 3 months of NET Inhibitors, inorder to get downregulation of NE receptors and anti-anxiety?
| null | 5 |
Hydroxyzine experiences
|
I suffer from depression, social anxiety and ADD symptoms.
Could you please tell me more about Atarax (Hydroxyzine) and its effects on your daily life, mood, anxiety, sociability, creativity, talkativeness, cognition, relaxation, sleep etc.? How has it changed your daily life and lifestyle and personality since beginning?
I‘m really interested in this med for years but never got to try it. It‘s taken as needed, right? Doesn‘t have to be taken daily or build up over weeks like antidepressants?
| 2 |
Doctors seem to not believe Rexulti has a withdrawal syndrome. Tips for getting off it?
|
Doctors seem to not believe Rexulti has a withdrawal syndrome, even though if you browse these forums you find countless accounts from people who have been on it long term having horrible, debilitating symptoms. My psychiatrist has said this, medical websites say this, basically the whole medical community, but this is not true. I saw someone say they felt like they permanently messed up their brain months after quitting (although they improved I believe). I tried to quit it once off of a low dose and the effects were horrible. Felt weird but acceptable for a few days, but then the side effects only increased with no signs of stopping over the next 2 weeks. It was hell, my brain just felt really messed up, couldn't do anything, movement disorder like stuff, muscles just felt bizarre, horribly dissociated. I had to start taking it again.
However, I know that it has had a dulling effect on my emotions and cognition and has put me even deeper into the horrible cognitive problems and worsened my condition. I already felt extremely dissociated, but now things are even less vivid. My idea is to quit it extremely slowly, maybe compound it in a liquid suspension.
Maybe there are people who can quit it without issues, but people who had problems quitting it after being on it long term: has anyone quit it a similar way, or another way? Did you have side effects? How long did they last?
| 3 |
Anyone else struggle with morning depression?
|
Its severe upon waking and gets better throughout the day. I can sleep all night but still be very sleepy all day.
I suspect HPA axis disregulation. Has anyone found any supplements that help with this, please? Perhaps something that lowers the cortisol awakening response?
Please and thank you.
| 11 |
Anyone else struggling with wanting to end it all….
|
Been on a 3 year journey with no end in sight. TRD, MDD, GAD. Have tried all kind of medicine, magic mushrooms, Kambo, TMS, ECT, Therapy and have been in the hospital 3 times. I mean seriously is there still hope? What else is there to try?
| 13 |
fetzima shortage
|
Our local pharmacies are not able to get fetzima, is there a manufacturering issue? Suggestions on where to get it and/or replacement med that works on similar receptors?
| 3 |
Are there benefits that come from having higher blood level of Lithium (within therapeutic range)
|
I’m technically in the therapeutic dose range at .6 I was wondering if I will have more benefits being at like .8 or 1 as opposed to my current .6 I’m very interested in these answers!
| 2 |
Add-On for anxiety (Nortriptyline + ? )
|
I'm on Nortriptyline 100mg since a few weeks and i like it so far, it helps my depression and my IBS and it doesn't kill my libido like the SSRI/SNRI i tried before.
However my social anxiety is pretty much the same. I wonder what i could take with my Nort? I thought about Buspirone (Buspar) or Pregabaline (Lyrica)? My doc is not a big help.
| 5 |
Menopause and Depression
|
So on a recent review with my GP agreed with my working hypothesis that this last MDD was triggered on balance by menopause.
And part of the problem was that the drop in hormones made Effexor a bit more unpredictable for me after more than 15 years of working fine.
I'm fortunate that he's a confident prescriber of psych meds and was happy to do Wellbutrin plus other drugs combination without referral to the psychiatrist.
We need to discuss how hormones influence mental health.
Please shout out if anyone wants to out themselves as mature and female to talk about things like mHRT
| 3 |
Have you found any consistent difference between SSRIs and SNRIs?
| null | 5 |
Solian (Amisulpride) Experience?
|
Anyone here have any experience with Amisulpride?
| 3 |
2nd time on bupropion - feeling terrible. anyone else?
|
I first took bupropion from Oct-dec 2021. Started on 150mg for about 4 weeks, bumped it up to 300mg in early November and went off it around christmas 2021 because it didn't seem to be helping much.
I remember it being a pretty low side effect, lowkey and \~somewhat\~ helpful med. The first week at 150 and at 300 each time, I would get a small but meaningful improvement in mood, energy, focus and enjoyment of everything else. Those tapered off into nothingness, with slight fatigue, poor sleep and maybe worse anhedonia starting around the 2nd week of 150 and 300, respectively. The long term effects seemed to me a mild anxiolytic effect and slight increase in general mental clarity; very little for anhedonia, motivation, and energy.
Today is day 8 and I've given bupropion 150 another go. same exact manufacturer.
I feel like shit. VERY tired, shit quality sleep, VERY restless and generally uncomfortable, unmotivated, lethargic, difficult to focus, and just mentally dead. Having trouble thinking of basic shit and following thru/completing tasks. anhedonia a lot worse. Took a lot of effort to even write this post. Crap mood and looking forward to nothing; hopeless.
What's changed is that I was super addicted to nicotine prior to starting wellbutrin, and am still currently vaping. I have also used phenibut/lyrica, kratom and adderall pretty heavily this year during college. Never was fully addicted to any of them though, maybe *mild* dependencies at kratom at certain points, but I don't believe I straight up withdrew from any of them.
I'm supposed to go on a big 2 week long vacation halfway around the world in 2 fucking days and I feel like garbage.
Should I stick to bupropion for now? anyone else had a similar shitty experience during the second go around? Thanks.
| 2 |
Buspirone - How Long Does It Take To Notice The Anxiolytic Effects?
|
Hi there,
I just started to take Buspirone for my anxiety issues. Do you notice the effects of Buspirone right away or does it need to build up in your system for a few weeks before any effects are detectable (like SSRI)?
| 4 |
Blood Work Showing Very Low Serotonin Serum
|
I haven't met with my doctor yet but I just got bloodwork results and they tested Serotonin serum. I've never been tested for this and didn't even know it was an option. Anyway it says that mine is less than 5 when normal is 31-207.
Does this mean that my brain and/or gut is producing very little serotonin? And if so, what medications would help?
| 2 |
How would you compare olanzapine with lurasidone?
|
I am very well settled on olanzapine, living more or less satisfactory life. But sometimes I wish I was more cognitively sharp.
I take meds such as methylphenidate and bupropion and atomoxetine and clonidine to help me do things.
Olanzapine doesn't interfere with these medicines. Most of the antipsychotics render these medicines useless for me. But this doesn't happen with everyone. Some can take both the types of drug just fine.
Latest drug I tried was Cariprazine. It rendered all my stimulating drugs useless. And it wasn't very stimulating in itself. I felt very slow on it and had to get off.
I am afraid that lurasidone will also render these medicines useless, like all antipsychotics in the past (amisulpride, aripiprazole).
| 2 |
I lowered the dose of antidepressant. Now I feel more tired and sleepy.
|
I've been using Cipralex 20mg for over a year now. Recently I started to therapy and lowered my dose to half cause I was too numb to talk when I was on full dose. It feels fine regarding anxiety and depression, plus I feel more like myself but I feel so drained, so tired and sleepy all the time. I also started to take vitamin D, B1, B6, B12 and some mineral supplements but they're no use. I can't even keep up with work hours. I return to home like dead and sleep 10 hours. I can't find energy to do anything.
Edit: Is it normal? Is this phase temporary or permanent?
| 1 |
Just morning Thoughts
|
Everybody talk about seek help if u feel depressed but actually it's pretty difficult as i found it , when u jump in adult life u have allot work on front of u to realize how adult world work , but all friends and stuff kinda fade away specially that adult life it's pretty good at sorting out who was real friend so life is becoming pretty lonely even if u have partner u don't want to just throw ur problems straight cause u are worried to not put this weight on them they care of u so they would be worried, so as i tried to jump on some apps which are meant to help in difficult time , idea is great and all but it's not working pretty well, it's hard to open yourself on difficult situation specially open up to just random person out there. Especially that everyone have own preferences to trust ppl idk why probably it's mark of your childhood , it's weird how ur brain can trick u to sort out ppl u can trust only because of they gender , age etc does only i have that or u feel the same way ?
| 2 |
What is average monthly cost of Ketamine treatment in UK?
|
This is how I understand it:
There are 2 ways to get ketamine for treatment of depression in UK:
1) Go to a special "ketamine clinic" where they inject you with the stuff. I don't know how many times per month is the typical number.
2) Esketamine nasal spray. I think you also need to go to a hospital to have this administered. And again, I don't know how many times per month is the typical dosing frequency.
I have heard of a thing called "Ketamine troches" but I don't think this is currently available in UK. Correct me if I'm wrong.
I've heard Ketamine treatment for Depression, either way, is mega expensive.
So please clear this up: what is typical monthly cost for ketamine treatment in UK for depression?
| 5 |
i want to share my prblems
|
So.... long story but everythink started after getting Covid-19 in 2020 iv'e get diagnosed , with my gf and get isolation information . It was terrible i was freaking out about it so much ppl tell about how deadly this deseas was but actually we did not have to hospitalize ourselves but there my mental health an my physical health get preety messed up . So just after covid i was getting pretty easy catch pneumonia almost like every month at least once my body was week and doctors try to give me antibiotics in like 6 months iv'e eaten like 7 antibiotics which was not really smart as my other doctor said cause it can mess up my organism more . so i started to support my body more with vitmins and stuff and it get better a bit , but it was calm not for long tho just some time after iv'e get intestines pain and some stuff happenning with my digestive system and there everything started to break in pieces in my head first of all iv'e run to the internet too search for solutions , internet says it was cancer ofc . Then mi mind was getting preety messed up no sleep at night , anxiety , when i try to go sleep i was getting so scared of something , sweating it felt almost like i lost my mind completly i lost control on myself for shure . Finally iv'e got to doctor which diagnosed H. pylori get antibiotics and other medicines to get ride of it and life started to be a little easier no pain in stomach at least . But that would be to easy if its end like this lymphadenopathia joined to my life my lymph nodes
gets big like bigger than 2 cm and a bit painfull , ofc iv'e got to doctor which said propably thats a lymphoma and sendet when he sai that to my my world just fell off in pieces even more which i thought it can not be worse anxiety get stronger strong depression come i felt already like a dead man , didn't think anymore about myself all i thought what with my familly and my gf like i did not want to break their hearts but they saw iv'e changed much they realise that im in reallly bad shape . luckilly Biopsy shall nothig to worry about there was no cancer cells all blood tests gets preety normal but for me was to late already at least for my mental health iv'e get maniac about getting some deadly disease more worried about myself than about anything else . Everything what was happening later and is happening now getting me down even more . War on Ukraine nuclear threat , China and stuff i dont know what to do , once at the instigation of my gf iv'e go to psycholoogists but actually i dont think it was someone who should i visit with this types of problem but when she told me i should sometimes go to walk or something to calm myself down i did not felt like someone treat me serious so i give up on it . So now u know a little at which point of my pshychical condition i'am ,and today as every day morning i waked up turn on some tik tok and i see stuff like cancer , deadly fungus , and nuclear threat , WW3 threat and stuff and i think i decided to get detox off internet just a break for a while , and im gonna try to find help for myself somehow . i wanted to share that with everyone cause even typing stuff helps me a bit and i belive would help many ppl so feel free to talk even in prviate.
PS: Sorry for my bad english and grammar im not really good at this language , actualy i come from one of the slavic countries
| 1 |
Looking for ways to combat Glutamate rebound/surge
|
Is anyone familiar of the feeling, when you take a stimulant, for a few hours, everything is OK, but when the effects starts wearing off, it feels like someone is sucking the life out of you? During that time, I feel like something is wrong, like I did something wrong! A feeling of anxiety, uneasiness, impending doom, a feeling of sickness, suffering and inner pain. It's quite similar to the feeling of uneasiness just before an intense, and awful stomach pain.
Does anyone knows any kind of trick/hack to shut this thing off?
The only solutions I know about is to take a fast acting NMDA Antagonist i.e. an NMDA Antagonist with a short half life, But it's impractical due to their legality (in the case of Ketamine, at least). DXM is problematic because it's a half SSRI, and then it's problematic to take if you're planning on taking MAOIs soon. When I had this "Glutamate rebound" feeling I used to take a DXM pill and it used to clear it intensely and effectively within 15 minutes or so. Does anyone know about any other solutions to combat this?
Edit: I just took 20mg propranolol, let's see if it would do help with that.
Edit 2: Not only that it didn't help, it even made it worse.
| 1 |
Life ruined from permanent sexual dysfunction from antidepressants. Help!!
|
I have PSSD which is post SSRI antidepressant sexual dysfunction. I took an SSRI for only 25 days back in 2019 and have been ruined ever since. Yes it’s rare but very possible, just read all the stories at r/PSSD if u don’t believe me. I now have had numb emotions, no libido and no pleasure or feeling in orgasms for almost 4 years. It’s totally life ruining. No, I’m not going to another doctor to make it worse. I’m so desperate, I miss so badly how I felt before taking those stupid pills.
| 6 |
treat me like slave!
|
My parents treat me like slave I am very depressed I try to quit many times but I can't my parents infact everybody treat me like a slave they don't give me proper food I haven't eat since 9 days 😔
| 0 |
Wellbutrin and hydroxyzine
|
Hi I'm on wellbutrin 300mg and I also take hydroxyzine 50mg at night did anyone's hydroxyzine just not work anymore? It has worked for me to sleep in the past but now it just isn't doing it for me. Am I the only one?
| 1 |
Spravato vs TMS
|
I have a consultation with a clinic my psych referred me to and she suggested that I try to get a combination treatment of both spravato and TMS however insurance will only cover one at a time, I have fairly decent coverage (shout out to the sacrifice of salary as a state employee for good health benefits) I am trying to decide whether to try the spravato first since it’s shorter and less commitment and from what I’ve read can be a quicker way to get to remission of symptoms or to go with TMS first since it is “longer lasting”
I’ve been on 11 anti depressants since 2009 with some chunks of time with giving up on the medications and trying to do a alternative treatment option (yoga, exercise, mindfulness, journaling, vitamins, etc) and I just stopped taking Prozac after the worst 6 weeks of my life and I’m exhausted and just want to feel some sort of relief to motivate me and keep my journey to a balanced and healthy mind/life going forward. I am so tired of the side effects and the weight gain (which also doesn’t help with the depression) and time lost to trying medication after medication and adjusting doses and tapering off and dealing with brain zaps and withdrawal from one med to another I JUST WANT RELIEF, even if it’s only a brief period or a slight positive difference it would make the world of difference for me.
I know everyone is different so I realize some people respond well to one vs the other but I am the person who wants to be as informed as possible when making a decision so I’d love to hear your advice if you’ve tried either and why you chose that option or both and which you did first/liked best
Appreciate you in advance 🫡
| 4 |
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