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0.476437
628b980569ba4529849f90ec1bc8f7fe
Number of subjects for each visit during the 2-year period. HP, hyperopes (SER > +0.5 D); EM, emmetropes (−0.5 D ≤ SER ≤ 0.5 D); MYO, myopes (SER < −0.5 D). The values in the boxes represent the number of participants at each visit. The values in the solid circles indicate the number of participants whose refractive status shifted from one group to a more myopic group. Four emmetropes at baseline and one myope at the first-year visit (dashed circles) were found to have refraction rebound (i.e., hyperopic shift from one group to another). For the four emmetropes, the mean change was +0.38 ± 0.14 D; for the one myope, the change was +0.18 D. Note that the data for the four subjects who had shifted from the EM group to the HP group at the first-year follow-up visit were excluded from analysis of the refractive status changes of the emmetropes (dataset 3).
PMC10117224
iovs-64-4-16-f002.jpg
0.436305
5b490f8ff5aa4dcca0bb4a356b002345
(a) Peripheral refractor with the arrangement of fixation targets in the vertical direction. Data covering a visual field of 60° × 35° were recorded. (b) Example of a 2D PR map. The origin of the coordinates corresponds to the fovea of the subject, and the optical nerve is approximately located 17° to the nasal side. The map is color coded, with red indicating greater hyperopia and blue indicating greater myopia.
PMC10117224
iovs-64-4-16-f003.jpg
0.387309
04254eb81bd54400876d05d174ad77ff
Average 2D PR maps for the different subgroups. (a) One-year visit. (b) Two-year visits. Subjects were classified into three refractive groups according to their initial refraction at baseline visit: HP (SER > +0.5 D), EM (−0.5 D ≤ SER ≤ 0.5 D), or MYO (SER < −0.5 D). At the first- and second-year visits (b), these groups were further divided based on their refractive changes into slight-, moderate-, and fast-progression groups. Spherical refraction values are color coded, with red indicating relatively hyperopia, blue indicating relative myopia, and yellow–green indicating zero defocus. Map coordinates on the x-axis show the horizontal meridian, with positive values being the nasal retina (temporal visual field) and negative values the temporal retina (nasal visual field). For the y-axis, positive values indicate the superior retina and negative values the inferior retina.
PMC10117224
iovs-64-4-16-f004.jpg
0.496569
2e0b7f168f244eff95fa82a7372c78db
Average 2D PR maps, relative (a) and absolute (b), for emmetropic children from baseline to the second follow-up visit. Subjects were assigned to three categories based on the status of their central refractive error over the 2 years. Category 1 (EM-EM-EM) corresponds to the group that remained emmetropic during the entire period. Category 2 (EM-EM-MY) corresponds to the group that was emmetropic at baseline and at the first follow-up but had developed myopia by the second follow-up visit. Category 3 (EM-MY-MY) corresponds to the group that was emmetropic at baseline but had developed myopia by the first follow-up visit. Spherical equivalent refraction values are color coded, with red indicating relatively hyperopia, blue indicating relative myopia, and yellow–green indicating zero defocus. Map coordinates on the x-axis show the horizontal meridian, with positive values being the nasal retina (temporal visual field) and negative values the temporal retina (nasal visual field). For the y-axis, positive value indicate the superior retina and negative value indicate the inferior retina.
PMC10117224
iovs-64-4-16-f005.jpg
0.384362
42c5d7615bbb4c948e0e3a7f8836f557
Correlation analysis for refraction in the superior retina and myopia progression in 2 years. (a) The change of central refraction as a function of superior SER over the 2 years. (b) The change of axial length as a function of superior SER over the 2 years. The superior refraction was calculated as the average from a representative region: (−3 ≤ x ≤ 3) and (8 ≤ y ≤ 12), for a total of 35 data points. Data from emmetropes and myopes are presented as red and blue dots, respectively, and as the corresponding fit line. The data for hyperopes were excluded from the figures due to the limited sample size.
PMC10117224
iovs-64-4-16-f006.jpg
0.464331
1bd5f4db8e1f491b8efd5848989641a6
Multilayer perceptron (MLP) neural networks architectures. (A) Linear MLP with 64 bit OHE. (B) Linear MLP with 3 × 4 bit OHE. (C) MLP with embedding layer (dimension = d) and rectifying linear unit ReLU activation functions. The Ws are the matrices whose elements are the learnable parameters. y, ground truth value. ŷ, predicted value.
PMC10117997
frai-06-1128153-g0001.jpg
0.502872
241444c69a984440a3f7a4a4fb2c275f
Schematic representation of the Recurrent Neural Network (RNN): baseline architecture showing a single RNN layer, adapted from Karpathy (2015). The Ws are the matrices whose elements are the learnable parameters. yt, ground truth value at t. ŷt, predicted value at t.
PMC10117997
frai-06-1128153-g0002.jpg
0.457419
24ca0e611d26476fa266766d02d59152
Histograms of the codon distribution in human transcriptome (A). Codon frequency distribution in human ribosomal proteins transcripts (B). Amino acid frequency distribution in all human proteins (C). Amino acid frequency distribution in human ribosomal proteins (D). Pink bars: most frequent codon in (A, B) or most frequent amino acid in (C, D). The red dots show hypothetical uniform distributions for comparison with the observed distributions.
PMC10117997
frai-06-1128153-g0003.jpg
0.49849
ef6eac0042f84c13a058d676a6ef8d20
Impact of embedding layer and dimensionality on accuracy and loss: (A) Training and test accuracies. (B) Training and test losses. (C) d = 10 embedding first two features after 40 epochs. (D) d = 2 embedding features after 40 epochs. (E) Genetic code table as deciphered at epoch 16 for MLP OHE 64 bits with two hidden layers of size 64 and 128 and with codon embedding layer d = 2.
PMC10117997
frai-06-1128153-g0004.jpg
0.42912
023595d2d7d3468f9a79d673d64ae395
Impact of one-hot encoding size and network architecture on training accuracy and loss. One-Hot encoding 64 or 3 × four bits with and without weights adjustment: (A) Training and test accuracies. (B) Training and test losses. (C) Training and test accuracies comparing architecture and hidden size. (D) Training and test losses comparing architecture and hidden size. (E) Genetic code table as deciphered at epoch 3, for RNN two stacked layers of hidden size 256. Note that the stop codons (UAA, UAG, and UGA), tryptophane (UGG), cysteine, and tyrosine have not yet been unequivocally deciphered.
PMC10117997
frai-06-1128153-g0005.jpg
0.440317
fed2416ee9504d5380f168ea20292943
Sequential changes in the surface ECG parameters after TH and amiodarone treatment.(A) Representative ECG parameters (QRS duration, QT interval, and TpTe interval) at BT (upper panel), TH (middle panel), and amiodarone/TH (lower panel) of pig 3 during SR. The ECG parameters analyzed included the following: (B) QRS durations, (C) QT intervals, (D) QTc intervals, and (E) TpTe intervals. TH increased all ECG parameters compared with BT. However, even under TH, amiodarone treatment further increased the durations of all ECG parameters. These data were derived from all the six pigs from this study. *P < 0.05, BT vs. TH; #P < 0.05, TH vs. Amiodarone/TH, both by the paired t-test. The data were presented as means ± standard deviations. BT, baseline temperature; ECG, electrocardiography; QTc, corrected QT; TH, therapeutic hypothermia; TpTe, T-peak to T-end interval.
PMC10118167
pone.0282943.g001.jpg
0.440254
6d909d1d0f6b4358aac1fe9932b37b10
Sequential changes in the TAT after TH and amiodarone treatment.(A) Sequential changes in the TAT after the induction of TH and amiodarone infusion (amiodarone/TH) either during SR (left panel) or RVP (right panel). These data were derived from the six pigs from protocol I. (B) Representative isochronal map of pig 1 during SR (left panel: BT, middle panel: after TH, and right panel: after amiodarone infusion). The Panel B showed a left anterior-oblique (LAO) view to the heart. The upper part indicated anterior aspect of the heart and the lower part indicated the posterior aspect of the heart. From a LAO view, the LV was in the right side and RV in the left side. The landmark was highlighted in yellow color. The white color on the map indicated the earliest activation site and followed by red, orange, yellow, green, light blue, blue, and purple color. *P < 0.05, BT vs. TH; #P < 0.05, TH vs. Amiodarone/TH, both by the paired t-test. The data are presented as means ± standard deviations. BT, baseline temperature; LV, left ventricle; RV, right ventricle; RVP, right ventricular pacing; SR, sinus rhythm; TAT, total activation time; TH, therapeutic hypothermia.
PMC10118167
pone.0282943.g002.jpg
0.405837
1694311d5d0a4a4fbd80621dfa46e1fe
Global and regional changes in the CV.(A) Sequential changes in the CV after TH or amiodarone treatment during SR or RVP. A sequential reduction in the CVs was observed after TH and amiodarone treatment. These data were derived from all the six pigs from this study. *P < 0.05, BT vs. TH; #P < 0.05, TH vs. Amiodarone/TH, both by the paired t-test. (B) Interval changes between BT and TH (ΔCV between BT and TH) and between TH and amiodarone/TH (ΔCV between TH and amiodarone/TH) in the different epicardial segments. These data were derived from all the six pigs from this study. The interval changes in the CV in segment 8 (anterior mid right ventricle) were significantly greater than those in all the other segments. *P < 0.05, ΔCV between BT and TH in segment 8 vs. the other segments in the post-hoc analysis with the Bonferroni method. (C) The color-coded polar map of the interval changes between BT and TH (ΔCV between BT and TH) and between TH and amiodarone/TH (ΔCV between TH and amiodarone/TH) in the different epicardial segments. Each color indicated different degree of decrease in the CV.
PMC10118167
pone.0282943.g003.jpg
0.480236
14e402c1db384a50abdf229794d4a5bd
Global and regional changes in the LE duration.(A) Sequential changes in the LE duration after TH or amiodarone treatment during SR or RVP. These data were derived from all the six pigs from this study. A sequential reduction in the LE durations was observed after TH or amiodarone treatment. *P < 0.05, BT vs. TH; #P < 0.05, TH vs. Amiodarone/TH, both by the paired t-test. (B) Interval changes between BT and TH (ΔLE durations between BT and TH) and between TH and amiodarone/TH (ΔLE durations between TH and amiodarone/TH) in the different epicardial segments. These data were derived from all the six pigs from this study. The interval changes in the LE durations in segment 8 (anterior mid RV or posterior mid RV) were significantly greater than those in all the other segments. *P < 0.05, ΔLE durations between BT and TH in segment 8 or segment 9 vs. the other segments in the post-hoc analysis with the Bonferroni method. (C) Representative bipolar electrograms of segment 8 and segment 1 from pig 4 during BT, TH, and amiodarone/TH demonstrating sequential prolongation of the LE durations.
PMC10118167
pone.0282943.g004.jpg
0.46138
165032dcdf7e48528194d15826aed67f
Changes in the wavelet activation pattern, the vulnerability to ventricular arrhythmias after amiodarone treatment during TH, and Regional differences in the connexin 43 expression during TH and amiodarone treatment.(A) Representative isochronal activation from pig 1 according to the pre-specified segments. During SR, the earliest activated site was the apical area (segment 13), and the latest activated site was the outflow tract area (segment 1) at BT. After TH, the latest activated site changed to the anterior basal RV (segment 2). After amiodarone infusion during TH, the latest activated site moved back to the outflow tract area (segment 1). During RVP, the earliest activated site was the posterior basal right ventricle (segment 3), and the latest activated site was mostly (83.3%) the posterior basal LV (segment 5) at BT. At TH, the latest activated site mostly changed to the anterior basal LV (segment 6, 66.7%). At amiodarone/TH, the latest activated site moved to the posterior basal LV (segment 5, 50%) in half of the pigs. (B) The incidence of ventricular arrhythmias after burst RVP. The vulnerability to ventricular arrhythmias was tested in 4, 4, and 3 pigs with BT, TH, and amiodarone/TH respectively. The vulnerability to ventricular arrhythmias of pigs with amiodarone/TH group was higher than the pigs at BT and the pigs with TH (P = 0.021).
PMC10118167
pone.0282943.g005.jpg
0.446042
2bee41bb249d41bdab992dda6a17e7cd
Regional differences in the connexin 43 expression during TH and amiodarone treatment.(A) Left panel: Comparison of the connexin 43 expressions among segment 8 (anterior mid RV wall), segment 5 (posterior basal LV wall), and segment 12 (anterior mid LV wall). The data are presented as box plot. These data were derived from pig 3, pig 4, pig 5, and pig 6 from the protocol I. Right panel: Comparison of the connexin 43 lateralization among segment 8 (anterior mid RV wall), segment 5 (posterior basal LV wall), and segment 12 (anterior mid LV wall). The data are presented as box plot. These data were derived from pig 3, pig 4, pig 5, and pig 6 from the protocol I. (6 slides from each segment of each pig) The parameters between the three segments were compared using one-way ANOVA. (B) Presentative fluorescent images of the connexin 43 expressions. Left panel: anterior mid RV (segment 8 of pig 6); middle panel: posterior basal LV (segment 5 of pig 5); right panel: anterior mid LV (segment 12 of pig 4). Green fluorescence: connexin 43; blue fluorescence: 4,6-diamidino-2-phenylindole for nucleus. BT: baseline temperature; LV = left ventricle; RV = right ventricle; RVP = right ventricular pacing; TH = therapeutic hypothermia.
PMC10118167
pone.0282943.g006.jpg
0.515918
d893d5374a4a477abd0b66d119d8f1f7
Industry 5.0 tools for serving the ophthalmology patients
PMC10118223
12647_2023_633_Fig1_HTML.jpg
0.394808
149bfa96cb254b3388f145b8ee9e8e6b
Pictorial representation of the digital health model used during COVID-19 [41]
PMC10118223
12647_2023_633_Fig2_HTML.jpg
0.535917
270442acebff4758a8168f3d7a98c874
Prime benefits of Industry 5.0 for ophthalmology
PMC10118223
12647_2023_633_Fig3_HTML.jpg
0.398062
fec3e9577bcd48839ecd270f3c9f2230
Flow diagram of study cohort.
PMC10118757
2359-4292-aem-66-06-0856-gf01.jpg
0.58428
b96e8c5dd9be4341adaabde947f23bb7
Predicted in-hospital mortality according to logistic regression model by glucose coefficient of variation in all patients presented by locally weighted scatterplot-smoothing (LOWESS) curve.
PMC10118757
2359-4292-aem-66-06-0856-gf02.jpg
0.470735
18d36a770708468bbe82f96a60d4d631
Episode cost function of simulation experiment 1 in Table 1
PMC10119544
10729_2023_9636_Fig1_HTML.jpg
0.396166
827048003272481a982830234c4c48ed
Optimal policy: number of surgeries scheduled every day for Q0 and Q1 from the randomly selected cases
PMC10119544
10729_2023_9636_Fig2_HTML.jpg
0.425571
52d517db207d4b8b990877ae019432c8
Optimal policy: timeline of 100 randomly selected surgeries from Q0
PMC10119544
10729_2023_9636_Fig3_HTML.jpg
0.434836
8f9768a3fe70471ea4a52378b71dd267
Histogram of (a) number of days to clear the backlog \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$Q0$$\end{document}Q0, and (b) number of surgeries missing due days for the optimal policy with 100 \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$Q1$$\end{document}Q1 simulated cases
PMC10119544
10729_2023_9636_Fig4_HTML.jpg
0.427244
aa6d0508af054cd5936fc12f98131fc3
A MLP network for one-step-ahead forecasting based on two lagged terms.
PMC10119839
41598_2023_33784_Fig1_HTML.jpg
0.498709
9f749796773e495bb1c60876d2ad516f
Graphical representation of monthly air traffic data for the years 2010–2019.
PMC10119839
41598_2023_33784_Fig2_HTML.jpg
0.391416
0b9f9d135fca4f01b33b36b32b2b958d
Monthly averages of air traffic data for the years 2010–2019.
PMC10119839
41598_2023_33784_Fig3_HTML.jpg
0.402976
7094daee341f494db5f0de11ffe61568
Graphical representation of the series of air traffic data for the years 2010–2019 after applying the differentiation process.
PMC10119839
41598_2023_33784_Fig4_HTML.jpg
0.422222
ae0629e224fb49049dcf062e094aa0ca
Forecasts for the years 2020–2024 with the help of the SARIMA(1,1,1)(1,1,1)12 model.
PMC10119839
41598_2023_33784_Fig5_HTML.jpg
0.409498
a51acf9fd71d44b19203abb11da5f347
MLP model.
PMC10119839
41598_2023_33784_Fig6_HTML.jpg
0.381536
33306b4bb972452c803dfcf83d2ef376
Forecasts obtained using the MLP model.
PMC10119839
41598_2023_33784_Fig7_HTML.jpg
0.428157
02e211fc1b524b1bbe7db28619cd05ff
Comparison of the forecasts obtained with the help of the MLP model and the actual air traffic density.
PMC10119839
41598_2023_33784_Fig8_HTML.jpg
0.511878
71da9d24d9b449c5b75713c4b0475296
Study flowchart. Note: CCHS = Canadian Community Health Survey.
PMC10120422
195e354f1.jpg
0.393604
e77214e1e6ce40b7ad2d13d01ca25ae2
(A) Large field-of-view 3D SHINKEI image in the coronal plane showing the sciatic nerves (yellow arrows) in a healthy control; (B) Manual segmentation of the sciatic nerve slice-by-slice in the axial plane using the fat-suppressed T2-weighted acquisition (binary mask shown in yellow); (C) Segmentation of the sciatic nerve shown in the sagittal plane (binary mask shown in yellow).
PMC10121559
41598_2023_33618_Fig1_HTML.jpg
0.542932
f7e76f1aaa4b41149a12fc0f491ef0e9
Schematic illustration of the healthy sciatic nerve cross-sectional anatomy at the level of the upper thigh, highlighting the main biological correlates of all qMRI metrics obtained in this study. In the healthy sciatic nerve, the main biological compartments underlying the qMRI metrics are myelin, intra-axonal water (in both myelinated and unmyelinated axons) and extra-axonal space (endoneurium). However, metrics can also be influenced by surrounding tissue compartments (e.g., perineurium, lipid equivalent connective tissue). Note: Although qT1 is known to be sensitive to myelin, the overall macroscopic T1 is rather unspecific, and is likely to be influenced by almost all biological compartments shown (e.g., myelin, amount of intra- and extra-axonal water, as well as potential exchange between the two water populations). 
PMC10121559
41598_2023_33618_Fig2_HTML.jpg
0.435523
07146efcf68a4b38999c9a718a3a4368
Example maps of standard diffusion tensor (DTI) derived metrics axial/radial/mean diffusivity (AD/RD/MD) and fractional anisotropy (FA), diffusion kurtosis imaging (DKI) metrics axial/radial/mean kurtosis (AK/RK/MK), quantitative magnetisation transfer (qMT) metrics bound pool fraction and bound pool transverse relaxation time (BPF/T2B) and quantitative longitudinal relaxation time (qT1), in the sciatic nerve of a healthy control.
PMC10121559
41598_2023_33618_Fig3_HTML.jpg
0.401708
625f3b797c804ac4824d4dcd8a0ccf8c
Boxplots with mean (± SD) values of the standard diffusion tensor (DTI) metrics axial/radial/mean diffusivity (AD/RD/MD) and fractional anisotropy (FA), diffusion kurtosis imaging (DKI) metrics axial/radial/mean kurtosis (AK/RK/MK), quantitative magnetisation transfer (qMT) metrics bound pool fraction and bound pool transverse relaxation time (BPF/T2B) and quantitative longitudinal relaxation time (qT1), in the sciatic nerve of 12 healthy volunteers.
PMC10121559
41598_2023_33618_Fig4_HTML.jpg
0.41362
2fdb23eeb0ec4a94ad09d766b711a17b
Flow chart of the methodology used for the article search.
PMC10123610
jfmk-08-00039-g001.jpg
0.416533
c28041e3063048db9abcf22cace9d609
Map of countries whose leagues have been included in relevant surveys (the colour of the bubble represents the number of studies in which they have been included).
PMC10123610
jfmk-08-00039-g002.jpg
0.416805
76abbab7237145d3a2a60409c9dafd7f
Number of articles by year and category.
PMC10123610
jfmk-08-00039-g003.jpg
0.472917
56fce4df5189439eb7b8e19f40629ec3
Classification of playing styles identified by Factor-PCA in each of the game phases.
PMC10123610
jfmk-08-00039-g004.jpg
0.451743
bf1112c1b9a248039abd82daac1339d8
Proportion of articles based on contextual variables and game phases in which their effect on teams’ playing styles was studied.
PMC10123610
jfmk-08-00039-g005.jpg
0.43554
26db36e4f31b43bbac8de46ade25877a
Mechanical structural design of anthropomorphic dual-arm robot.
PMC10123651
biomimetics-08-00169-g001.jpg
0.461298
ba757e8fbe5b464ab3f3426edb259fd4
The primary functional components of Kinect.
PMC10123651
biomimetics-08-00169-g002.jpg
0.444548
cac91a68eb6c45199f5cb77b30597d60
Data glove and its principal functional components.
PMC10123651
biomimetics-08-00169-g003.jpg
0.449214
51e681e796da453bb97d9c1e749e5f83
Bionic dual-arm robot system.
PMC10123651
biomimetics-08-00169-g004.jpg
0.420883
1c9b4283d7f944f786d4ea83151bc1b2
The display and installation of the dexterous hand.
PMC10123651
biomimetics-08-00169-g005.jpg
0.461053
9cf6df0708ef449682b45eefcccc6bdf
The double-arm anthropomorphic robot is constructed based on the improved DH method.
PMC10123651
biomimetics-08-00169-g006.jpg
0.463188
43951133788f4a3991fb0a89c6db15f2
The maximum working range of the anthropomorphic double-arm robots. (a) YZ plane view; (b) XY plane view.
PMC10123651
biomimetics-08-00169-g007.jpg
0.398793
c103e42d3c3048fdbafdb5820a8f3856
Schematic diagram of mathematical model of human elbow joint. (a) The angle control model analysis of the number 3 degree of freedom; (b) The angle control model analysis of the number 4 degree of freedom.
PMC10123651
biomimetics-08-00169-g008.jpg
0.453329
2f86634bf4f84a96baf7cd5d74683907
The area of the Kinect camera for capturing images (left); The skeleton points of the human body are recognized by the Kinect system (right).
PMC10123651
biomimetics-08-00169-g009.jpg
0.444774
211ec4fefb74419a998589a57d97b620
Experiment with Single Handed Control. (a) Single-arm shoulder joint swing action; (b) Single-arm shoulder joint horizontal extension; (c) Turned arm, palm up; (d) Single-arm horizontal forward flexion.
PMC10123651
biomimetics-08-00169-g010.jpg
0.416865
19ed230efd36466ba13e03dc77a4e65f
Experiment with double hand control. (a) Left arm raised, right arm swings sideways; (b) Left arm extended horizontally, right arm raised; (c) Left arm extended horizontally, right arm swings sideways; (d) Left forearm flexed down, right arm raised.
PMC10123651
biomimetics-08-00169-g011.jpg
0.400532
6a47d09ed69947dab7e522da00fa4782
Data gloves control dexterous hands in real time. (a) Five fingers open; (b) Thumb movement; (c) Controlled contact between index finger and thumb; (d) Clenching of the fist.
PMC10123651
biomimetics-08-00169-g012.jpg
0.400037
8ef9a4f1d3fb42c08d08d2854371af9b
Pressure feedback from the 16 contacts of the tactile sensor on the tip of the index finger when grasping the bottle.
PMC10123651
biomimetics-08-00169-g013.jpg
0.407287
9533e6c637c54181a9c6c91633d554ba
Data acquisition and filtering processing of joint position in x, y and z directions respectively. (a) Shoulder joint S; (b) Elbow joint E; (c) Wrist joint W.
PMC10123651
biomimetics-08-00169-g014.jpg
0.588858
71e6b52f78d34e87903ac906ba914889
Real-time acquisition and Kalman filtering of shoulder and elbow joint angles. (a) Acquisition and filtering of the shoulder joint 1 angle data; (b) Acquisition and filtering of the shoulder joint 2 angle data; (c) Acquisition and filtering of the elbow joint 1 angle data; (d) Acquisition and filtering of the elbow joint 2 angle data.
PMC10123651
biomimetics-08-00169-g015.jpg
0.433663
6dc8f0a2c030498899167c49f912dbeb
MRI brain DWI-ADC showing restricted diffusion involving the bilateral corona radiata (top images) and small areas of restricted diffusion involving the right anterior limb of the internal capsule and the right occipital white matter (bottom images).
PMC10123878
10.1177_2329048X231171011-fig1.jpg
0.436392
0ccb1889d1a249e6b08f84a9299fb898
Empirical distribution of bias for joint health state estimators under limited information.AUD indicates alcohol use disorder.
PMC10126182
nihms-1840828-f0001.jpg
0.462454
c2f3e6ca9c674e79b3243555bd489abf
Bone growth measured with SEM–EDX (a), SWLI (b), and CESAM (c). (a) SEM image of BAG granules A and B (left) and EDX elemental analysis of the content along the indicated scan line (right). (b) SWLI image of the sample (left) and topography along the scan line (right). (c) CESAM acoustic impedance map of the sample (left), and acoustic impedance (red) and topography (black) along the scan line. Regions of interest (i–vii) related to stages of bone formation (glass granule, Si-layer, HA-layer, epoxy, non-mineralized bone tissue, HA-layer, Si-layer) are indicated in each figure and discussed in detail in corresponding paragraphs. The acoustic impedance (c, red line) along the scan line is well explained by the elemental analysis from SEM–EDX (a), and the topography maps from SWLI (b) and CESAM (c) are in good agreement. Thus, CESAM encapsulates the relevant information for bone growth estimation.
PMC10126192
41598_2023_33454_Fig1_HTML.jpg
0.388406
6e79e57f511e492eb3d7c6cf82642629
Comparison of (a) SWLI image, (b) CESAM topography map, and (c) CESAM acoustic impedance map to determine regions-of-interest (ROIs) related to bone formation. Three areas (Area 1–3), showing ambiguous features in the topography maps, are indicated in all images. The acoustic impedance information in these regions assists in determining ROIs. Glass granules (A) and (B) are indicated.
PMC10126192
41598_2023_33454_Fig2_HTML.jpg
0.459169
1056127223fd4a8a830bc37ad544ef1f
Schematics of (a) CESAM and (b) SWLI. (a) The focused transducer transmits a frequency-modulated coded signal (linear chirp, 130–370 MHz), which is reflected from the sample surface, recorded with the same transducer and post-processed. Both topography and acoustic impedance maps are obtained from one scan. The sample is scanned in the XY-plane in water immersion. (b) The light is divided within the Mirau-type objective to two interfering optical paths: scanning and fixed reference. The resulting interference images are recorded by a camera as a function of piezo-controlled objective-to-sample distance, which are used to calculate the topographic map of the sample.
PMC10126192
41598_2023_33454_Fig3_HTML.jpg
0.432978
6ac7766607d0435da762f4a065250db0
The spectral change in Cf9212 due to FaRLiP is not observed in Syn7002. The room-temperature fluorescence spectra of Cf9212 whole cells were obtained with the excitation wavelength at 440 nm. (A) Cf9212 and (B) Syn7002 cells were grown in white light (WL, solid line) until the early exponential phase and then transferred to far-red light (FRL, dash line) for 48 h. Specific wavelengths of maxima are indicated above the peaks.
PMC10127269
sb3c00066_0002.jpg
0.458125
9fcb0cdee4224106b60e0be43ba70f5a
Validation of the expression of EYFP through fluorescence emission. Fluorescence emission (wavelength = 527 nm) per OD750 was recorded for each strain in three biological replicates in (A) Syn7002—wild type (WT), DWK0 (empty vector pRL1342Km), and DWKP (pRL1342Km-PcpcBA6803[eyfp])—and in (B) Cf9212—wild type (WT), DWE0 (empty vector pRL1342Em), and DWEP (pRL1342Em-PcpcBA6803[eyfp]). The fold change compared to WT is indicated at the top of each bar. Each error bar represents the standard deviation of three biological replicates. All the transconjugants were verified by colony PCR and DNA sequencing. Student’s t-test was used to compare the means between two groups; **, P < 0.01, ***, P < 0.001; ns, not significant.
PMC10127269
sb3c00066_0003.jpg
0.38105
138ac58dae434d47a03a5bd6f0fbad93
Selected promoter regions from the FaRLiP gene clusters in Leptolyngbya sp. JSC-1 and Syn7335. The FaRLiP gene clusters contain subunits from photosystem I (PSI, red), photosystem II (PSII, green), phycobilisome (PBS, blue), and regulators for FaRLiP (brown). The colored arrows represent the relative positions of the genes in the genomes. The labels above or below the arrows represent the names of the genes. The yellow curved arrows indicate the promoter regions selected for cloning. The double slash lines in Syn7335 indicate that the two segments of DNA sequences are located in different regions in the genome. Hyp, hypothetical protein; chlF, chlorophyll f synthase.
PMC10127269
sb3c00066_0004.jpg
0.454833
d2cdba1e590a49ce8029e70463707b27
Induction of promoters in Cf9212 in far-red light. Cf9212 strains were cultured in white light (WL) and then transferred to WL or FRL for 168 h. The fluorescence at a wavelength of 527 nm (EYFP) per unit of OD750 was measured in (A) WL and (B) FRL every 24 h. Each color represents one strain. Fold change indicates the fluorescence intensity per OD750 at each time point compared to the value at 0 h. Each error bar represents the standard deviation of three biological replicates.
PMC10127269
sb3c00066_0005.jpg
0.451153
64e0984dd94b49e7803a92e603fe4aa5
Far-red light does not activate PchlFJSC1 in Syn7002. Syn7002 strains were cultured in WL and then transferred to either WL or FRL for 192 h. The excitation wavelength was 488 nm. The fluorescence at 527 nm per unit of OD750 was measured in (A) WL and (B) FRL. Fold change indicates the fluorescence intensity per OD750 at each time point compared to the value at 0 h. Each error bar represents the standard deviation of three biological replicates.
PMC10127269
sb3c00066_0006.jpg
0.442272
d6eb0f11ee2049c78e80f0b90a8113f2
Effect of light intensity on the induction of PchlFJSC1. The strain DWER01 was cultured in WL (100 μmol photons m–2 s–1) and then transferred to the same WL condition and FRL with four different intensities (50, 100, 200, and 300 μmol photons m–2 s–1) for 144 h. The excitation wavelengths were 488 nm for measuring the emission at 527 nm and 440 nm for measuring 680 and 724 nm emissions. Relative fluorescence emissions are shown as (A) fold change (the fluorescence intensity at 527 nm per unit of OD750 at each time point compared to the intensity at 0 h) and (B) fluorescence ratio at 724 and 680 nm (a measure of the magnitude of the FaRLiP response). Each error bar represents the standard deviation of three biological replicates.
PMC10127269
sb3c00066_0007.jpg
0.465325
49617c0f32e84bc9b42980032b5c005a
The induction of PchlFJSC1 is reversible. The strain DWER01 was cultured in FRL (50 μmol photons m–2 s–1) and then transferred to the same FRL condition, RL (50 μmol photons m–2 s–1), WL (100 μmol photons m–2 s–1), and WL (300 μmol photons m–2 s–1) for 60 h. The excitation wavelengths were 488 nm for measuring EYFP emission (527 nm) and 440 nm for measuring 680 and 724 nm emissions. Fluorescence intensities are shown as (A) ratio (the relative fluorescence intensity of EYFP per unit of OD750 at each time point compared to the intensity at 0 h) and (B) fluorescence emission ratio at 724 and 680 nm (reflecting the relative magnitude of the FaRLiP response). Each error bar represents the standard deviation of three biological replicates.
PMC10127269
sb3c00066_0008.jpg
0.430618
3a827e9714a941fa997714fc70702c2a
Optimized structures and energies obtained from DFT calculations performed at the ωB97XD/def2-TZVP/def2-QZVP (Cu) (scrf = smd, toluene)//ωB97XD/6-31G(d,p)/SDD+f (Cu) level for (a) σ-allyl-Cu(I) intermediates Ia and Ib and their most favorable π-olefin Cu(I) complexes with allylic gem-dichloride 2 and for (b) the stereochemistry-determining oxidative-addition transition states associated with the most favored pathways leading to (S)-3,Z,Z and (R)-3,Z,Z using KOtBu and (c) using LiOtBu.
PMC10127276
cs3c00536_0001.jpg
0.408174
395ac349f4eb42d9ad9ed01850676502
Optimized structures and energies obtained from DFT calculations performed at the ωB97XD/def2-TZVP/def2-QZVP (Cu) (scrf = smd, toluene)//ωB97XD/6-31G(d,p)/SDD+f (Cu) level for stereochemistry-determining oxidative-addition transition states associated with the most favored pathways leading to (S)-3,Z,Z and (S)-3,Z,E.
PMC10127276
cs3c00536_0002.jpg
0.429119
5e8111c5dbee4ffda1c818cb9867999f
Enantioselective Allyl–Allyl Cross-Coupling
PMC10127276
cs3c00536_0003.jpg
0.392104
afc5ce11296f4a36a24126b9c384f221
Scope of the Enantioselective Borylative Coupling of Allenes and Allylic gem-DichloridesUnless otherwise noted, all reactions were performed on a 0.2 mmol scale under optimized conditions (Table 1, entry 11). Yield values refer to isolated products. Z,Z/Z,E selectivity is reported in brackets.Reaction run on a 1 mmol scale using 5 mol % of the catalyst.Reaction run at 40 °C over 48 h.Reaction run at 60 °C.
PMC10127276
cs3c00536_0004.jpg
0.493559
98d236dcf1fb43dea36233929cd323d0
Synthetic Modifications of ProductsConditions: (i) Pd(PPh3)4 (10 mol %), NaOH 2M, dioxane, 100 °C; (ii) Pd2(dba)3 (5 mol %), XPhos (10 mol %), CsF (3 equiv), dioxane, 100 °C; (iii) NaBO3·4H2O (5 equiv), THF:H2O, rt; (iv) LDA (2.5 equiv), THF, −78 °C, 5 min.
PMC10127276
cs3c00536_0005.jpg
0.445852
498bf9a94e77467c85d69c9bb671f389
Findings on an arterial phase contrast-enhanced computed tomography image. The image reveals the jump bypass and external iliac artery (EIA) graft on the ventral side of the superior rectal artery (SRA). IIA, internal iliac artery; IMV, inferior mesenteric vein; SA, sigmoid artery.
PMC10129159
ms9-85-1243-g001.jpg
0.466546
9844f5da7c724c4f9c6cdf57db390192
Intraoperative findings. The lateral approach allowed mobilization of the sigmoid mesocolon while exposing the artificial artery (arrows).
PMC10129159
ms9-85-1243-g002.jpg
0.441805
f08aa2d9853a48568be2b1c4163969c9
Macroscopic findings of the resected specimen. The specimen shows a type 2 lesion measuring 15×8 mm.
PMC10129159
ms9-85-1243-g003.jpg
0.553482
fa23656f74994bd49dac819883bf2c66
(A, B) Fundus photograph of the right and left eye shows golden-yellow reflex (the Mizuo–Nakamura phenomenon). (C, D) Fundus photograph of the right and left eye shows normal fundus color, after 2 h of dark adaptation.
PMC10129271
ms9-85-0918-g001.jpg
0.437545
fab23dd16ede40fe998d4451f1f31a37
(A, B) Optical coherence tomography cross-sectional of the right and left eye shows high-intensity regions in the outer segment. (C, D) Optical coherence tomography cross-sectional shows the disappearance of these deposits and normal intensity.
PMC10129271
ms9-85-0918-g002.jpg
0.419245
6b7915a691d94dfcba5f5907293169a8
Composite materials used to form haemostatic sponges and their mechanism of action.
PMC10130630
gr1.jpg
0.452497
639214e1ad1f42a9be7209a73e833e58
Haemostatic chitosan sponges. (1) Alkylated chitosan-diatom bio silica sponge. A). The schematic diagram representation of AC (Alkylated Chitosan) and AC-DB (Alkylated Chitosan-Diatom Bio silica sponges; B). The haemostatic process of AC-DB (Alkylated Chitosan-Diatom Bio silica) sponge (X [47]. (2) A schematic representation of the synthesis of OBC, OBC/CS, and OBC/COL/CS haemostatic sponges [55].(3) S-CS/TPM haemostasis (sponge containing tilapia peptides and chitosan) and its haemostatic evaluation are depicted schematically [46].
PMC10130630
gr2.jpg
0.532669
1010fed6d61f4336ba156ba8709df283
Chitosan/gelatin/oxidized cellulose sponges studied in-vitro and in-vivo as absorbable haemostatic agents according to the schematic diagram [53].
PMC10130630
gr3.jpg
0.439093
58fcdad1714d4c96a991d10b238eebd3
The schematic diagrammatic representation of starch-based macroporous sponges (KR-Sps) covalently labelled with the antimicrobial peptide KR12 via the highly efficient thiolene photo click (SH-PEG-HS; dithiol-functionalized poly (ethylene glycol), St-gel: Potato starch gel, KR-Sp: KR12 immobilized starch-based sponge) [57].
PMC10130630
gr4.jpg
0.439662
102bff0f96984acaa97d5f46e8cba990
The ACGS20 (N-alkylated chitosan/graphene oxide porous sponge with 20% ratio) haemostasis mechanism is depicted in a schematic diagram [45].
PMC10130630
gr5.jpg
0.396818
1a3d57c04fcd49688680a9f8879f3171
Schematic Diagram of the preparation of (a) cationized dextran (poly (2-dimethyl amino)-ethyl methacrylate)-grafted dextran (Dex-PDM)) and (b) haemostatic sponges [5].
PMC10130630
gr6.jpg
0.453547
0d986bdc96114078bdc5d60b3f1572f0
Available commercial sponges on the market.
PMC10130630
gr7.jpg
0.413646
8473e84d9b2e455e88c7f145af305b07
Chitin/corn stalk/Ag NPs composite sponge. (a) Depiction of a schematic for the preparation of Ag NPs. (b) Illustration of a schematic preparation of a chitin/corn stalk/Ag NPs composite sponge and the antibacterial haemostatic process [68].
PMC10130630
gr8.jpg
0.41873
4367b423e07e4228aa88109ae171ca46
Schematic diagram showing the haemostasis mechanism of PDA/SiNP. (a) Formation of clots at the site of vessel injury after applying PDA/SiNP. (b) The potential haemostasis mechanisms of PDA/SiNP [139].
PMC10130630
gr9.jpg
0.406125
5a4f5727a76e4f7ebd8f7e1af87b8cab
Surprisal functions of stimuli i and j, and the calculation of the associated efforts Ei and Ej.
PMC10130781
gr1.jpg
0.450422
471568f73c8a480a81bd9eb791e65a9d
Transcriptions of four drum patterns. (a) Generic backbeat pattern. (b) “Change The World” (stimulus 8). (c) “Bravado” (stimulus 13). (d) “Rock Steady” (stimulus 39). The author would like to thank Florian Hoesl for preparing Fig. 2.
PMC10130781
gr2.jpg
0.423887
75b6e7682e6a4b3aabf47927ea595fbe
Scatterplot of estimated complexity (γˆi) on the x-axis and the empirically measured perceived complexity (βˆi) on the y-axis. These values are listed in Table 1, Table 8.
PMC10130781
gr3.jpg
0.40746
1e9ff6d374534cb3b7fd7fad8a0996b7
Histograms: (a) Values of the strength of the prior (λ), calculated on the 10,000 simulated training sets. The mean was at λ=3.56 and a 95% prediction interval spanned (2.7, 4.8). (b) Values of the model fit (R2) between the empirical βˆi and the estimated γˆi, calculated on the 10,000 test sets. The mean model fit was R2=.835.
PMC10130781
gr4.jpg
0.396699
790d5a4233724e72a4d2b0c7fc57d6fe
Surprisal plots for four drum patterns. (a) Backbeat pattern. (b) “Change The World” (stimulus 8). (c) “Bravado” (stimulus 13). (d) “Rock Steady” (stimulus 39). Each value of the surprisal function represents one row sum of the surprisal matrix, which is the sum of the surprisal for all three instrumental layers combined at one point in time.
PMC10130781
gr5.jpg
0.403379
a8b1f84162e0411795b54a391c013f3c
Update matrix U with ones highlighted (bold, gray background).
PMC10130781
gr6.jpg
0.404313
06474ec8a31e4402acbccfc165beb073
Flow chart of the literature search.
PMC10130960
WJP-13-182-g001.jpg
0.401971
9741f8ad5d0f4b558182d5223fa4a889
Chest computed tomography scans of patient. A: At admission and before surgery show bilateral pulmonary infection and complete compression and atelectasis of the right lung. Postoperative chest computed tomography (CT) demonstrates right lung expansion; B: Chest CT scan showing the destruction of the right upper lung; C: Both the presence of pus in the pleural cavity and iodine gauze in the emphysematous pleural space are observed. The residual cavity is eliminated after surgery; D: The coarctation of the right intercostal space is noted on chest CT. The patient’s right chest wall deformity has almost resolved, 6 months after the operation.
PMC10131018
WJCC-11-2282-g001.jpg
0.442028
a275ec5bcd224e6e98d89a9d3f1d9de5
Bronchoscopic view of the right upper bronchus. A: Bronchoscopy at admission shows a 5 mm fistula (white arrows) of the right upper bronchus, along with erythema, erosion, and hyperplasia of the apical bronchus, and a small amount of necrotic material; B: Bronchoscopy is performed 1 mo after the anti-tuberculosis treatment; C: Bronchoscopy is performed 6 mo after the anti-tuberculosis treatment.
PMC10131018
WJCC-11-2282-g002.jpg
0.413645
420f1b0b26c64f0aa1f3378d32ce3ff4
The timeline of treatment and procedures. TB: Tuberculosis; BPF: Bronchopleural fistula.
PMC10131018
WJCC-11-2282-g003.jpg
0.444993
75554979868f40ff8c6cc5eb8d8b998f
Intraoperative and postoperative findings. A: Open-window thoracostomy was performed on the patient; intraoperatively, mold was noted on the pleural surface; B: No effusions were noted in the pleural cavity and no lesions were seen on the pleural surface.
PMC10131018
WJCC-11-2282-g004.jpg