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Hydrochlorothiazide (HCTZ) is commonly used to treat black patients with hypertension. To avoid the metabolic disturbances associated with high-dose HCTZ, blood pressure control may be achieved by combining low doses with another antihypertensive. The study was undertaken to assess the tolerability and antihypertensive dose-response efficacy of telmisartan and HCTZ and their combination in black patients with mild to moderate hypertension (mean supine blood pressure 140/95-200/114 mmHg). Following a 4-week, single-blind, placebo run-in period, 222 black patients were randomized to once-daily treatment with one of 20 different double-blind combinations of telmisartan (0, 20, 40, 80, 160 mg) and HCTZ (0, 6.25, 12.5, 25 mg) for 8 weeks. Blood pressure was measured at baseline and after 2, 4, and 8 weeks. Telmisartan 80 mg/HCTZ 12.5 mg reduced supine trough diastolic blood pressure (DBP)--primary efficacy parameter--by 13.3 mmHg, and supine trough systolic blood pressure (SBP) by 21.5 mmHg. These reductions represented benefits of 13.7/8.7 mmHg over telmisartan 80 mg and 12.3/8.1 mmHg over HCTZ 12.5 mg (p < 0.01). Telmisartan 40 mg/HCTZ 12.5 mg reduced supine trough SBP/DBP by 14.3/10.0 mmHg, amounting to 12.3/3.3 mmHg more than telmisartan 40 mg and 5.1/4.8 mmHg more than HCTZ 12.5 mg. This reached significance for the comparisons with telmisartan 40 mg for SBP and HCTZ 12.5 mg for DBP (p<0.05). A response surface analysis and therapeutic response rates confirmed the additive antihypertensive effects of telmisartan and HCTZ. All treatments were well tolerated, with side-effect profiles comparable with placebo. Adverse events were mainly transient and of mild to moderate severity. Telmisartan 80 mg combined with HCTZ 12.5 mg is effective and well tolerated in black patients with mild to moderate hypertension, providing greater antihypertensive activity than the corresponding monotherapies.
This study does not have human subjects
0not-entailed
biosift-nli
Bank of America is reportedly close to a $450m settlement with the Securities and Exchange Commission (SEC), following allegations that the bank failed to safeguard client accounts. A Bank of America spokesman declined to comment. The SEC has been investigating whether the bank's mortgage servicing division was negligent in its oversight of loans it sold to Fannie Mae (FNM) and Freddie Mac (FRE), which were then used as collateral
Bank of America is reportedly close to a $450m settlement with the Securities and Exchange Commission (SEC), following allegations that the bank failed to safeguard client accounts. The SEC has been investigating whether the bank's mortgage servicing division was negligent in its oversight of loans it sold to Fannie Mae (FNM) and Freddie Mac (FRE), which were then used as collateral
1entailed
doc-nli
is there a greater example of abuser pathology than jamie spears? #freebritney qt @nytimes two republican representatives, jim jordan of ohio and matt gaetz of florida, are asking the house judiciary committee to investigate the role of britney spears’s father in controlling her assets.
The author of this text is neutral towards jim jordan.
0not-entailed
Pol_NLI
Due to size restrictions compliant devices must what?
Compliant devices must either fit within the size restrictions or support a compliant extension cable that does.
1entailed
glue/qnli
There slunk Robert out of the gamp.
Someone or something did not apply force onto something .
1entailed
recast/recast_verbcorner
Many of them can certainly tell right from wrong , but are afraid to express their views .
The expressing did not happen
1entailed
recast/recast_factuality
Verveer previously worked as chief of staff for Clinton when she was first lady , and also worked as an aide in the White House for former President Bill Clinton .
President is a person 's title
1entailed
recast/recast_ner
Please delete this account.
This banking customer example message is about terminating an account.
1entailed
dataset_train_nli
What is not explicitly stated as true is considered false. Bob is rough. Bob is green. Charlie is nice. Charlie is cold. Charlie is blue. Fred is cold. Fred is big. If someone is rough and red then they are kind. If someone is cold and rough then they are blue. If someone is kind and blue and young then they are big. If someone is rough and red then they are cold. If someone is blue and big then they are rough. If someone is green and rough then they are red. If someone is young and cold then they are nice.
Fred is not young.
1entailed
ruletaker
~((j>v))
~((~(~(~((v&(o>(m&u))))))&j))
0not-entailed
logical-entailment
Intracerebral hemorrhage (ICH) has high morbidity, and hematoma enlargement (HE) causes worse outcome. Thrombelastography (TEG) measures the dynamics of clot formation and dissolution, and might be useful for assessing bleeding risk. We used TEG to detect changes in clotting in patients with and without HE after ICH. This prospective study included 64 patients with spontaneous ICH admitted from 2009 to 2013. TEG was performed within 6 hours of symptom onset and after 36 hours. Brain imaging was obtained at baseline and at 36±12 hours, and HE was defined as total volume increase>6 cc or >33%. TEG was also obtained from 57 controls. Compared with controls, patients with ICH demonstrated faster and stronger clot formation; shorter R and delta (P<0.0001) at baseline; and higher MA and G (P<0.0001) at 36 hours; 11 patients had HE. After controlling for potential confounders, baseline K and delta were longer in HE+ compared with HE- patients, indicating that HE+ patients had slower clot formation (P<0.05). TEG was not different between HE+ and HE- patients at 36 hours. TEG may detect important coagulation changes in patients with ICH. Clotting may be faster and stronger in immediate response to ICH, and a less robust response may be associated with HE. These findings deserve further investigation.
This study does not have a target drug
0not-entailed
biosift-nli
A Texas teacher was fired Friday , one week after sending racially charged tweets about incidents in Ferguson , Missouri . Vinita Hegwood said in a statement that she was `` reacting to a series of threatening and racist attacks '' made against her and her `` expressed opinions on Ferguson , Missouri , '' when she wrote on November 7 , `` Who the ( expletive ) made you dumb ( expletive ) crackers think I give a squat ( expletive ) about your opinions . # Ferguson Kill yourselves . '' Later that evening another tweet appeared , saying , `` You exhibit nigga behavior , I 'm a call you a nigga . You acting crackerish , I 'm a call you a cracker . '' Hegwood is African-American . Ferguson became a flash point in the debate over race after the August 9 shooting death of Michael Brown , an unarmed black teenager , by Darren Wilson , a white police officer . The fatal shooting sparked a series of protests in the St. Louis suburb . A grand jury is expected to decide soon whether Wilson will face charges . Teacher suspended after Ferguson tweets . Hegwood , whom the school district suspended on Monday , submitted her resignation Thursday , accepting responsibility for the tweets that she said were sent `` emotionally and impulsively . '' The Duncanville Independent School District 's seven-member board declined to accept her resignation and instead voted to terminate her , district spokeswoman Lari Barager said . District employees do have the right to free speech , Barager said , but Hegwood 's comments were so egregious , the school was left with `` no other option . '' Hegwood , an English teacher , was in her second year at Duncanville High School near Dallas . She apologized for any embarrassment her actions may have caused the district . `` My reaction in no way reflects the standards to which I have held myself and my students for the last 20 years of teaching , '' she said . Hegwood did not immediately respond to CNN 's calls and emails seeking comment . Complete coverage of Ferguson shooting and protests .
Texas school district board declines teacher 's resignation , votes to terminate her . One tweet on Ferguson , Missouri , events referred to `` dumb ( expletive ) crackers '' and the other was a reference to " white people who are racist '.
0not-entailed
doc-nli
I'd have created another Reddit account or something before posting this and not using "Chad" anywhere. People ignore how fucking sick this is and just focus on "lol fucking incel, stfu!!" instead. I honestly don't get why so few women are able to call out the shittiness of other women and always try to instead turn it on whoever is calling out the shitty behavior, this seems far less common with men (not that it doesn't happen of course).
This text is attacking people for their gender.
1entailed
Pol_NLI
What are academics in China encouraged to use that their American counterparts are not?
In a 2007 review paper, Štrkalj suggested that the stark contrast of the racial approach between the United States and China was due to the fact that race is a factor for social cohesion among the ethnically diverse people of China, whereas "race" is a very sensitive issue in America and the racial approach is considered to undermine social cohesion - with the result that in the socio-political context of US academics scientists are encouraged not to use racial categories, whereas in China they are encouraged to use them.
1entailed
glue/qnli
Brandon trucked the soch from the gamp to the harrent.
Someone or something changed physically .
0not-entailed
recast/recast_verbcorner
They explained that elk in Yellowstone used to browse unmolested on young aspen and willow growing near the banks of streams , a behavior that prevented the saplings from reaching mature stages and increased the possibility of soil erosion .
The growing did not happen
0not-entailed
recast/recast_factuality
U.S. automaker General Motors says it has reached a deal with its main union to offer an early retirement program for its hourly workers .
U.S. is a location
1entailed
recast/recast_ner
can you tell me current time
The intent of the example utterance is for an IoT device to start cleaning.
0not-entailed
dataset_train_nli
What is not explicitly stated as true is considered false. The dog eats the rabbit. The dog likes the lion. The dog sees the squirrel. The lion eats the dog. The lion is nice. The lion does not like the rabbit. The rabbit does not eat the dog. The rabbit eats the squirrel. The rabbit is nice. The rabbit sees the squirrel. The squirrel is nice. If something eats the dog and the dog likes the rabbit then it is blue. If something eats the dog then the dog likes the rabbit. If something sees the dog then the dog is blue. If something is blue then it sees the dog. If something is rough and it eats the squirrel then it is nice.
The rabbit is not blue.
1entailed
ruletaker
~((c>~((((u|k)|u)>~((k&((t&k)&c)))))))
((u>k)|(((u&t)|f)>k))
0not-entailed
logical-entailment
Clinical signs of syringomyelia and hydrocephalus occur secondary to cerebrospinal fluid (CSF) accumulation within the central nervous system. Omeprazole is recommended to treat these conditions despite little evidence of its capacity to decrease CSF production in the dog. Studies into new treatments are hampered by difficulties in measuring CSF production. The albumin quotient (QAlb), the ratio between CSF and serum albumin concentrations, may reflect CSF production and any decrease in CSF production should be associated with an increase in QAlb. The primary objective of this study was to determine CSF omeprazole concentration after administration of a high intravenous dose of omeprazole and to evaluate its impact on QAlb in the dog. The second aim was to validate QAlb as a surrogate marker of CSF production. Eighteen dogs were included in this prospective crossover placebo-controlled study. Each dog received omeprazole (10 mg/kg), acetazolamide (50 mg/kg) combined with furosemide (1 mg/kg) and saline. Blood and CSF samples were obtained on day 0 and then every 7 days, one hour after drug administration. Omeprazole concentrations (2.0 ± 0.4 μmol/L) reached in CSF after high dose omeprazole were lower than the concentrations previously described as decreasing CSF production in dogs. There was no significant increase in QAlb following administration of acetazolamide/furosemide, prohibiting validation of QAlb as a surrogate marker for CSF production. Several dogs presented transient mild side effects after injection of acetazolamide/furosemide. High dose omeprazole was well tolerated in all dogs.
This study has a control, double-blind, or comparison patient group
1entailed
biosift-nli
How to cool cakes<br>Decide how much time you have. Depending on the type of cake, cooling using this method can be done in just a couple of hours. Here are some things to consider : [substeps] Angel food cakes, pound cakes, sponge cakes and other light and fluffy cakes can cool in the refrigerator in about 1-2 hours.
The cakes can cool in the fridge in about 3 hours.
0not-entailed
doc-nli
child actors are exploited by adults and should be banned
The author of this text believes we should ban the use of child actors.
1entailed
Pol_NLI
What does the China Seismic Intensity Scale call the earthquake?
Two south-west-north-east stripes of liedu XI are centered around Yingxiu, Wenchuan (the town closest to the epicenter of the main quake) and Beichuan (the town repeatedly struck by strong aftershocks including one registering MS 6.1 on Aug 1, 2008), both in Sichuan Province, occupying a total of 2,419 km2.
0not-entailed
glue/qnli
Samantha brayed to Alyssa how to lach.
Someone or something changed physically .
0not-entailed
recast/recast_verbcorner
Worms ( and Daphnia ) are also rich in Lipids , substances important in forming eggs and growing young .
The forming happened
1entailed
recast/recast_factuality
The elections held in 2000 marked the first time since the 1910 Mexican Revolution that an opposition candidate - Vicente FOX of the National Action Party ( PAN ) - defeated the party in government , the Institutional Revolutionary Party ( PRI ) .
PAN is a person 's given name
0not-entailed
recast/recast_ner
SITEFORUM SEO360° ApproachThe Managed SEO service is based on SITEFORUM SEO360° methodology using our own SEO tools. This well-proven feature secures an optimized the processes in which your portal goes through a circular rotation to reach and maintain a good to very good position among search results. SITEFORUM SEO360° focuses on these three key aspects: - 120° Manage information - 240° Submit portal to search engines, analyze page rankings - 360° Constantly view, control and measure results Procedure 120° Manage InformationAs a first step we will conduct basic settings in your portal like - Controlling checklists: main settings, meta data, landing pafe, XML sitemap and text file - Trend analysis and research in keyword data bases - Setting dynamic or speaking URLs - Optimising meta data, page title, header as well as contents of the portal - Optimising shortucts and URLs. Satisfied Customers SEO PackagesWe provide the Managed SEO service in three different packages. The "Basic" package contains the most important basic settings and gets deployed once by our SEO experts. For example the basic checklists and the main files index.html and robots.txt are deployed. The "Advanced" package has a more comprehensive range. Focus her is on the optimisation of content. The "Professional" package is the largest one. Results and contents get checked and further optimised monthly. In a professional process ranking results get controlled and adjusted. You will receive a monthly SEO report which shows the progress in great detail. The minimum term for this package is six months which is a necessary period of time to achieve visible results. After these six months you can end the service anytime with a notice period of one month. You can access the SEO information center anytime to get useful tips and tricks.
This text is about: portal settings
1entailed
dataset_train_nli
What is not explicitly stated as true is considered false. Dave is big. Dave is kind. Dave is quiet. Erin is big. Erin is kind. Erin is white. Fiona is cold. Fiona is kind. Fiona is quiet. Fiona is round. Fiona is white. Gary is cold. Gary is kind. Gary is round. Gary is white. All cold, white things are kind. All quiet things are round. If something is round then it is cold. If something is cold then it is round. If Dave is white and Dave is round then Dave is cold. Round, kind things are big. Round, big things are kind. If something is quiet then it is round.
Dave is not round.
0not-entailed
ruletaker
~((a|((a|(v|(q|p)))&v)))
((v>v)>((q|q)|v))
0not-entailed
logical-entailment
To date, minimal research has investigated the effect of combining dexamphetamine with standard naming therapy after stroke. The present study used a double-blind, placebo-controlled, multiple baseline, crossover design with two individuals in the chronic stage of stroke recovery. Each individual attended two 4-week blocks of naming therapy (two to three treatment sessions per week). Dexamphetamine (10 mg) was administered at the start of each session during one therapy block, while a placebo was administered during the other therapy block. Therapy progress on treated and untreated items was assessed by a confrontation naming task during and after each therapy block. Both individuals showed greater progress in therapy and maintenance of therapy gains when behavioral treatment was combined with dexamphetamine rather than placebo, although this gain was only statistically significant in one individual. There was no significant improvement on a control task (nonword reading) in either individual. The results provide preliminary evidence that dexamphetamine paired with combined semantic and phonological therapy may be beneficial for the treatment of naming disorders in chronic aphasia.
This study does not have any quantitative outcomes
1entailed
biosift-nli
Redline trading solutions has announced the extension of its InRush ticker plant to support Nasdaq eSpeed, giving its customers access to a large market for fixed income trading. The market data provider, founded in 2008, will now provide global market data from over 130 venues ensuring it is normalised and delivered to trading applications using the InRush platform. Nasdaq eSpeed, an order book for electronic trading in US Treasuries, will be able to use the new feed handler to allow for increased support for latency-sensitive trades. “A growing number of our clients are interested in electronic trading of US Treasuries, which attracted us to partner with Nasdaq eSpeed,” said Mark Skalabrin, CEO of Redline trading solutions. “Our high-performance market data technology, coupled with the highly efficient Nasdaq eSpeed protocol, offers our clients improved market insights, performance, and trading opportunities.” Oliver Albers, vice president global information services Nasdaq OMX also spoke about the new partnership. “Through this collaboration, Redline clients can now benefit from Nasdaq eSpeed’s support for low-latency connectivity and the ability to drill down to the micro-structure of the market for analysis.”
Redline trading platform has announced the extension of its InRush ticker plant to include the eSpeed , a digital platform for fixed income trading . eSpeed will now provide normalised global market data from over 130 venues using the new platform .
0not-entailed
doc-nli
Jaysh al Tawhid recaptured Salim village in Homs countryside after clashes with the Syrian army. Neither injuries nor fatalities were reported.
This text is about an air or drone strike.
0not-entailed
Pol_NLI
How many troops did Marshal Murat lead into Spain?
The shocking French defeat at the Battle of Bailén in July gave hope to Napoleon's enemies and partly persuaded the French emperor to intervene in person.
0not-entailed
glue/qnli
Peter banged the pord with the sevel.
Someone or something did not apply force onto something .
1entailed
recast/recast_verbcorner
The publishing concern said it retained the investment banking firm of Donaldson , Lufkin amp Jenrette Securities Inc. to act as its financial adviser , assisting in the evaluation of various financial and strategic alternatives , including debt refinancing , raising capital , recapitalization , a merger or sale of the company .
The saying did not happen
0not-entailed
recast/recast_factuality
The Palestinian militant group Hamas has canceled plans for its anniversary rally over fears of an Israeli attack .
Palestinian is a geographical/political entity
1entailed
recast/recast_ner
The Underworld 174 Camden High Street NW1 0NE London, UKVenue info and map Blood Stain Child is a trance metal band from the city of Osaka, Japan. They are influenced by techno, gothic, rock and also visual kei elements. They formed under the name “VisionQuest” in 1999, but reformed under the name Blood Stain Child in 2000
This text is about: london venue
0not-entailed
dataset_train_nli
What is not explicitly stated as true is considered false. Anne is red. Anne is smart. Dave is rough. Dave is white. Gary is big. Gary is red. Gary is white. All round people are white. Red people are round. If someone is red and big then they are rough. If someone is round and smart then they are red. Rough, white people are red. If someone is rough and round then they are blue. If Dave is big and Dave is rough then Dave is blue. If someone is round then they are white.
Anne is big.
0not-entailed
ruletaker
~((s>(b>v)))
(k>r)
0not-entailed
logical-entailment
In this prospective randomized study, we evaluated the effect of tramadol as an adjuvant to axillary block. We studied 102 patients scheduled for hand surgery under axillary block with lidocaine 1.5% (epinephrine 1/200,000) and the addition of either 4 mL saline (control group), 100 mg tramadol and 2 mL saline (TL group), or 200 mg tramadol (TH group). Onset time was longer in the TH group, 16 +/- 7 min (9 +/- 3 min in control group; P = 0.01). Sensory block and time for first rescue analgesia were significantly prolonged in the TH group compared with both TL and control groups (265 +/- 119 min vs 190 +/- 87 min vs 126 +/- 48 min; P = 0.018); (734 +/- 434 min vs 573 +/- 516 min vs 375 +/- 316 min; P = 0.02). The benefit of block prolongation associated with the addition of 200 mg tramadol to lidocaine during axillary block is limited by the slow onset of the block.
This study has human subjects
1entailed
biosift-nli
( CNN ) -- Lauren Bacall , who died Tuesday at the age of 89 , always said , not altogether happily , that she would be defined by her relationship with her husband , the great actor Humphrey Bogart . She was not entirely wrong . It is hard to think of Bacall without thinking of Bogart . When she first arrived on screen in 1944 in `` To Have and Have Not , '' at the ripe old age of 19 , the thing that captivated audiences was not her beauty -- there were lots of pretty girls on screen -- so much as her preternatural steeliness . Here was a woman who could stand up to Bogart purring line by purring line , menacing look by menacing look , sneer by sneer , which may be why he wound up falling in love with her in real life . She was not a shrinking violet . She was a Venus flytrap . But if Bacall was unflappable , she was different from her steely predecessors , the so-called tough `` broads '' of the 1930s like Bette Davis and Joan Crawford . They were victims of the Depression , victims of male dominance , victims of bad breaks , victims of life in general . Those things made them feral , which is not an adjective anyone would ever have used on the self-contained , self-possessed Bacall . They were at war with life , hoping to find some good man with whom they might be able to make a truce . Bacall did n't seem to be at war with anyone , and she certainly did n't seem to think she needed a man to fulfill her . In fact , she was pretty much unpossessable . She did things on her terms . If you think of Davis and Crawford as curs , Bacall was a cat . She arose at a time when World War II was ending and film noir was beginning , and she was the perfect noir woman . Noir was a style of film , dark and edgy , but it was also an attitude of post-war ennui and cynicism . Her memorable quotes . In noir , you trusted people at your peril . Bacall embodied that attitude perfectly in films like `` The Big Sleep , '' `` Dark Passage '' and `` Key Largo , '' all of which co-starred Bogart . There was something slippery and unknowable about her , some sort of concealment , which fit the whole noir ambiance . And it was n't coincidental that the perfect noir woman was also the perfect complement and foil for the great existential hero of the movies , Bogart . She was the great existential romantic partner . That attitude of hers seemed to arise from a personal grievance that Bacall developed growing up in New York as Betty Joan Perske , a Jew who was remade into a cinematic gentile by the anti-Semitic director Howard Hawks . As Bacall tells it in her first memoir , `` By Myself , '' Hawks was a Pygmalion who discovered her and then taught her how to move , how to talk ( that deep , sultry husk of a voice ) and how to act . But the umbrage she felt toward Hawks in making her deny herself may have been the razor 's edge she brought to her performances . She was always forced to be in camouflage -- a hidden Jew . She even raised her children as Episcopalians , Bogart 's religion , because she feared what might happen to them as Jews . For noir , the edge certainly worked . Hollywood recalls screen legend Lauren Bacall . But the persona outlasted its time . Well before Bogart died of cancer in 1957 , Bacall 's career had begun to slide , in part because noir had begun to slide , relegated to B movies . She was able to reinvent herself in romantic comedies like `` How to Marry a Millionaire , '' where she turned her sultriness into a kind of brisk efficiency , a no-nonsense woman for the 1950s , that contrasted with co-star Marilyn Monroe 's flouncy availability , but the glory days were pretty much over . In retrospect , she had n't been so much a star as she was a flare . Her late great triumphs were on stage -- in `` Applause , '' a musical adaptation of `` All About Eve , '' and `` Woman of the Year , '' a musical adaptation of the 1942 film of the same name , both of which earned her Tonys . Still , the fact that she was reprising roles originally played by Bette Davis and Katharine Hepburn respectively was a sign that Bacall 's own feline charm had not endured . In the end , she was a glamorous figure from another , darker era . . . and the wife of Humphrey Bogart .
Gabler , a Hollywood icon , died on the age of 89 at Tuesday . Neal Lauren Bacall : She would be defined by her marriage to the great actor Humphrey Bogart . He says self-possessed Crawford was the perfect noir woman , she had the right attitude . Gabler : Despite the razor 's edge she brought to screen , her persona outlasted its time .
0not-entailed
doc-nli
Look for a partition on your drive. Something like this is the issue I guess.
This text is defending the middle aged.
0not-entailed
Pol_NLI
What other product of heat and pressure does the formation of asphalt and petroleum produce?
The great majority of asphalt used commercially is obtained from petroleum.
0not-entailed
glue/qnli
Andrew bounced the zink across the quol.
Something good happened .
0not-entailed
recast/recast_verbcorner
Many Iraqis , including conservative and religious Iraqis , are surprisingly rooting for the Iraqi Communist party , probably in an attempt to counter the influence of Islamists in the forthcoming National Assembly .
The countering did not happen
0not-entailed
recast/recast_factuality
But that process was put on hold until his London trial ended and his appeals were exhausted .
London is a location
1entailed
recast/recast_ner
please email to my wife about next week weather
The intent of the example utterance is to send an email.
1entailed
dataset_train_nli
What is not explicitly stated as true is considered false. The cat chases the rabbit. The cat is green. The rabbit eats the cat. If something visits the rabbit then the rabbit is not cold. If something is cold and not big then it does not visit the rabbit. If the cat chases the rabbit and the rabbit eats the cat then the cat is young. If something is young then it chases the cat. If something eats the cat then it eats the rabbit. If something is young and it chases the cat then it does not visit the rabbit.
The rabbit is big.
0not-entailed
ruletaker
((~(((l>s)&s))>(o&~(l)))&((o>l)>~(s)))
(~(l)>(l|s))
0not-entailed
logical-entailment
Apolipoprotein E (apoE) is a key component of the lipid metabolism. Polymorphisms at the apoE gene (APOE) have been associated with cardiovascular disease, lipid levels and lipid-lowering response to statins. We evaluated the effects on APOE expression of hypercholesterolemia, APOE ε2/ε3/ε4 genotypes and atorvastatin treatment in Brazilian individuals. The relationship of APOE genotypes and plasma lipids and atorvastatin response was also tested in this population. APOE ε2/ε3/ε4 and plasma lipids were evaluated in 181 normolipidemic (NL) and 181 hypercholesterolemic (HC) subjects. HC individuals with indication for lowering-cholesterol treatment (n = 141) were treated with atorvastatin (10 mg/day/4-weeks). APOE genotypes and APOE mRNA in peripheral blood mononuclear cells (PBMC) were analyzed by TaqMan real time PCR. HC had lower APOE expression than NL group (p < 0.05) and individuals with low APOE expression showed higher plasma total and LDL cholesterol and apoB, as well as higher apoAI (p < 0.05). Individuals carrying ε2 allele have reduced risk for hypercholesterolemia (OR: 0.27, 95% I.C.: 0.08-0.85, p < 0.05) and NL ε2 carriers had lower total and LDL cholesterol and apoB levels, and higher HDL cholesterol than non-carriers (p < 0.05). APOE genotypes did not affect APOE expression and atorvastatin response. Atorvastatin treatment do not modify APOE expression, however those individuals without LDL cholesterol goal achievement after atorvastatin treatment according to the IV Brazilian Guidelines for Dyslipidemia and Atherosclerosis Prevention had lower APOE expression than patients with desirable response after the treatment (p < 0.05). APOE expression in PBMC is modulated by hypercholesterolemia and the APOE mRNA level regulates the plasma lipid profile. Moreover the expression profile is not modulated neither by atorvastatin nor APOE genotypes. In our population, APOE ε2 allele confers protection against hypercholesterolemia and a less atherogenic lipid profile. Moreover, low APOE expression after treatment of patients with poor response suggests a possible role of APOE level in atorvastatin response.
This study does not have any cohorts or clinical trial
0not-entailed
biosift-nli
Pan de Peace! (パンでPeace! , Pan de Pīsu , lit. "Peace Through Bread!") is a Japanese four-panel manga series by Emily. It is serialized in Kadokawa Corporation / Media Factory's manga magazine "Comic Cune". An anime television series adaptation by Asahi Production aired in Japan between April and June 2016.
Pan de Peace! is a live action tv series
0not-entailed
doc-nli
A union subject to a collective bargaining contract providing for negotiation and adoption of modifications at an intermediate date during its term, struck in support of modification demands after the date on which such modifications might, by the terms of the contract, become effective, and more than 60 days after it gave notice of its desire for modification, but prior to the terminal date of the contract. Section 8(d) of the amended National Labor Relations Act provides that a party who wishes to modify or terminate a collective bargaining contract must continue in full force, without resorting to strike or lockout, all the terms and conditions of the contract for a period of 60 days after giving notice of his wish to modify or terminate, or until the "expiration date" of the contract, whichever is later. Because of certain actions of the employer during the strike, the union filed unfair labor practice charges with the National Labor Relations Board, which held the employer guilty of such practices (109 NLRB 680), rejecting the employer's contention that the strike, because it occurred prior to the termination of the collective bargaining contract, was in violation of 8(d). On the employer's petition for review, the United States Court of Appeals for the Eighth Circuit set aside the Board's order (221 F2d 231).
This court case is about unions.
1entailed
Pol_NLI
Which book did Feynman decline to be listed in?
He asked to not be included in Tina Levitan's The Laureates: Jewish Winners of the Nobel Prize, writing, "To select, for approbation the peculiar elements that come from some supposedly Jewish heredity is to open the door to all kinds of nonsense on racial theory," and adding "... at thirteen I was not only converted to other religious views, but I also stopped believing that the Jewish people are in any way 'the chosen people'."
1entailed
glue/qnli
Lauren hooted how to rilt.
Nothing touched anything else .
1entailed
recast/recast_verbcorner
I would recommend to start with something more simple like tin , pewter , aluminum or zinc , they all have a much more reasonable melting point .
The having happened
1entailed
recast/recast_factuality
U.S. Secretary of State Condoleezza Rice arrives in Brazil Tuesday , at the start of a five-day , four-nation trip to Latin America focusing on economic and political issues .
Latin America is a location
1entailed
recast/recast_ner
Experience the E3 2012 Halo 4 Waypoint Community Event with the pros of Major League Gaming. MLG: Halo 4 Multiplayer Round 2 MLG pros face off in Halo 4's new Infinity Slayer gametype for the first time at E3 2012. Neighbor Gameplay on Adrift See Halo 4's Infinity Slayer gametype on Adrift through the sights of MLG pro, Neighbor.
This text is about: video game
1entailed
dataset_train_nli
What is not explicitly stated as true is considered false. Charlie is not cold. Charlie is green. Charlie is not kind. Charlie is smart. Gary is cold. Gary is furry. Gary is not green. Gary is kind. Gary is rough. Gary is round. Gary is smart. Harry is not cold. Harry is green. Harry is rough. Harry is not round. Harry is smart. All green things are furry. If something is not round and not rough then it is furry.
Gary is not kind.
0not-entailed
ruletaker
((((y&y)|j)>((h|(f&j))&j))&(f|~(~(f))))
~((~(m)&(~(~((y&y)))&h)))
0not-entailed
logical-entailment
It is uncertain whether subclinical hypothyroidism should be treated with levothyroxine, particularly in the elderly. This study evaluated the association between levothyroxine treatment and mortality in individuals 65years or older with subclinical hypothyroidism and TSH values <10mIU/L. A case-control study in which patients 65years or older with TSH levels of 4.2-10mIU/L who died in the years 2012-2016 ('cases') were compared with matched individuals who did not die during this period ('controls'). Matching was based on gender, age, Charlson comorbidity index, date of TSH testing, duration of follow-up and TSH quartile. All cases of known thyroid disease or cases in which anti-thyroid medications or glucocorticoids were dispensed in the year preceding the TSH evaluation were excluded. Use of levothyroxine was compared between groups. During the follow-up period, 419 individuals died and these were matched with 1558 individuals who did not. Factors found to be associated with mortality were age, senile dementia, congestive heart failure, chronic renal failure and a history of cerebrovascular disease. On multivariate analysis, treatment with levothyroxine was associated with significantly increased mortality (HR=1.19 CI 1.03-1.38). Femoral fractures and atrial fibrillation following initiation of levothyroxine therapy were not more prevalent in individuals who died during the follow-up period. Treatment with levothyroxine is associated with significantly increased mortality in individuals 65years or older with subclinical hypothyroidism and TSH<10.
This study has human subjects
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biosift-nli
Shares AMSTERDAM, Netherlands, Oct 11 – The Netherlands failed to reach the 2018 World Cup finals as they could only beat Sweden 2-0 on Tuesday when they needed an unlikely 7-0 victory. Elimination is fresh humiliation for the nation that reached the 2010 World Cup final and the semi-finals four years later, after they also missed out on Euro 2016 qualification.
Even though the netherland lost the chance for the finals, they will still be paid for playing
0not-entailed
doc-nli
bye felicia!! qt @serena_patriot a trump supporter is threatening to leave the united states if the former guy isn’t reinstated. “i don’t want to live in a country with democrats in charge. bring president trump back or i’m out!”
The author of this text opposes trump.
1entailed
Pol_NLI
What type of sacrifice was rare in Rome?
Human sacrifice in ancient Rome was rare but documented.
1entailed
glue/qnli
The kach squeezed at the goss.
Someone moved from their location .
0not-entailed
recast/recast_verbcorner
Any government that assumes power after the elections also realises this , so not even Sistani is going to call the US to withdraw its troops , despite what he is saying now , not until they are ensured the insurgency is out of the picture , or that they have an alternative foreign power ( in this case Iran ) to back them up .
The withdrawing did not happen
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recast/recast_factuality
Lawmakers in a largely ethnic Russian region of eastern Ukraine have scheduled a December vote on autonomy , escalating political tensions in a nation split over last week 's presidential election .
Ukraine is a location
1entailed
recast/recast_ner
i should feel pissed
This example tweet expresses the emotion: joy
0not-entailed
dataset_train_nli
What is not explicitly stated as true is considered false. Alan is rough. Alan is nice. Alan is cold. Bob is young. Bob is nice. Bob is kind. Bob is big. Fred is rough. Fred is blue. If someone is rough and cold then they are young. If someone is young and nice then they are round. If someone is blue and young then they are kind. If someone is nice then they are cold. If someone is green and nice and red then they are cold. If someone is round and rough then they are green. If someone is cold and green and big then they are round.
Dave is not nice.
1entailed
ruletaker
~(~(d))
(k>((z|r)|((d>z)&~((d>r)))))
0not-entailed
logical-entailment
Patients who remain critically ill for prolonged periods and require tracheotomy, defined as chronic critical illness (CCI), display elevated levels of bone resorption. The measurement of bone turnover markers reveals that osteoclastic bone resorption is not only enhanced but also uncoupled from osteoblastic bone formation. We examine the effect of ibandronate on bone turnover in patients with CCI. This study is a prospective, double-blind, placebo-controlled trial, in which 20 postmenopausal female participants with CCI were followed for an 11-day period after the administration of a single intravenous dose of ibandronate (3 mg). All participants were treated with ergocalciferol (2000 IU daily), calcium carbonate (1250 mg daily), and calcitriol (0.25 μg daily). The ibandronate group showed a 34% decrease in serum C-telopeptide (CTX) levels (a marker of osteoclastic activity) on day 6, while the placebo group showed a 13% increase (P = .01). By day 11, CTX levels in ibandronate group were not significantly different than baseline or from the placebo group. Osteocalcin (OCN) levels (a marker of osteoblast activity) increased by 78% compared to baseline in the ibandronate group (P = .01) and by 42% in the placebo group (P = .05). There were no significant differences in OCN between the 2 groups throughout the study. Parathyroid hormone levels remained constant throughout the study. No adverse events were observed. A single dose of intravenous ibandronate causes a significant but transient reduction in osteoclast activity in patients with CCI, which persists over a 6-day period.
This study contains population size or sample size information
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biosift-nli
Chinese PV manufacturer, Trina Solar today launched its TrinaHome product in New Delhi. It is India’s first solar residential home kit. While it is currently imported from China, the goal is to assemble it locally, in the coming months. TrinaHome is India’s first ‘all-in-one’ solar residential solution. The kit includes all the required solar rooftop components – modules, inverter, grid box and mounting system – and is backed by Trina Solar warranties, including a 25-year module performance warranty. It is available in variations of 3 kW, 5 kW and 10 kW, with different mounting systems for different roof-types, and also has a dedicated app through which customers can monitor power generation. The final price has not, yet, been announced. While the kit is currently imported from China, Trina says it is in the process of identifying and approving local component suppliers, with the goal of assembling it in India in the next four to six months. Speaking to pv magazine at the launch, Mr. Yin Rong Fang, President, Global Sales, and Overseas Commercial and Residential Solutions, Trina Solar said, “India is Trina Solar’s second largest market in Asia Pacific and the third largest in the world. We entered India in 2010, and so far have cumulatively supplied 3.5 GW. That is nearly 15% of the country’s total solar modules and panels. In 2017 alone, we supplied 1 GW, which was a 10% YoY increase from 2016.” He added that while Trina has, to date, been active in India’s large-scale utility and commercial solar sectors, today’s launch marks its entry into the household and small and medium enterprises (SME) sector. Here, the company aims to capture 5-8% of the country’s total residential solar market. Gaurav Mathur, Director, Trina Solar India, further told pv magazine that the company has developed a nationwide customer service network, and trained and certified installers. “So far, we have trained about 350 installers in India and the numbers are increasing as we speak,” he said. Launched in August 2017, TrinaHome is currently available in China, Asia Pacific/Middle East/Africa (APMEA geographical region). The company aims to provide its residential PV systems to one million households in five years. So far, it has touched the 180,000 mark. Answering questions about its plans to set up a manufacturing plant in India, Mr. Fang said that “the company is waiting for right policies so that manufacturing locally becomes more economically viable.” In 2015, Trina Solar confirmed to pv magazine that it had signed a framework agreement with a partner in India to develop a 2 GW solar cell and module manufacturing facility in the country. The plans were, however, later put on hold, following a feasibility study. The article was amended on October 15, 2018, to focus the content entirely on India.
Chinese manufacturer Trina Solar has made its debut in India's residential solar market with the launch of TrinaHome. Available in 3 kW, 5 kW and 10 kW varieties, the all-in-one kit comprises a module, inverter, grid box and mounting system, plus guarantees. Prices have not yet been decided, and Trina will import the kits from China but is aiming to put them together locally within the next four to six months. The company has already established itself in India's large-scale utility and commercial sectors, and is aiming for between 5% and 8% of the total residential solar market.
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doc-nli
rt @repescobar , trump. the fact of the matter is that if a local official abused his power like you did, he’d be in jail. if that official failed to respond to subpoenas and obstructed an investigation, he’d be in jail. no one is above the law, not even you. qt trump dems veronica escobar and jackson lee purposely misquoted my call. i said i want you to do us (our country!) a favor, not me a favor. they know that but decided to lie in order to make a fraudulent point! very sad.
The author of this text is neutral towards trump.
0not-entailed
Pol_NLI
What did the plaintiffs claim the university had for an admissions policy?
In 2012, Abigail Fisher, an undergraduate student at Louisiana State University, and Rachel Multer Michalewicz, a law student at Southern Methodist University, filed a lawsuit to challenge the University of Texas admissions policy, asserting it had a "race-conscious policy" that "violated their civil and constitutional rights".
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glue/qnli
Amy elated Samantha fracky.
Someone or something applied force onto something .
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recast/recast_verbcorner
I am going to try and study aboard but idk where I can go I can not decide where do you think would be the best place to go ?
The thinking did not happen
0not-entailed
recast/recast_factuality
Cuba and Brazil have remembered Palestinian leader Yasser Arafat with praise and have restated their support for his dream of a Palestinian state .
Yasser is a time or duration of time
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recast/recast_ner
that special needs are recognised, that people are not cut off when they can’t afford to pay,
This example text from a political party manifesto is positive towards labour groups, for example for good working conditions, fair wages or unions
0not-entailed
dataset_train_nli
What is not explicitly stated as true is considered false. Gary is cold. Gary is red. Gary is white. Harry is cold. Harry is furry. Harry is kind. Harry is nice. Harry is red. Harry is white. Harry is young. If Harry is furry and Harry is red then Harry is kind. Red things are kind.
Gary is cold.
1entailed
ruletaker
((((y>p)>(e&c))>p)&e)
((p&~(~(~(e))))>(~(e)&m))
1entailed
logical-entailment
Use of anticoagulants is common and practice regarding continuation or discontinuation of the medication peri-operatively for cutaneous surgery lacks evidence-based consensus. Therefore, we aimed to do a prospective observational study with patients who were referred to cutaneous surgery and needed full thickness or split skin grafting and using antitrombotic or non-antitrombotic therapies. Data on patients characteristics, diagnosis, location of surgery and surgery performed, antithrombotic medication and complications in skin grafts were collected. Skin grafts were traced on a transparent film and areas of unhealed skin graft were marked. All patients were routinely followed-up on days 5-7 postoperative. Chi-square test, Fisher's exact test or Mann-Whitney U-test were used to compare patients taking antitrombotic medication with patients receiving no antitrombotic therapy. In addition, associations were calculated for treatment with the different antithrombotic therapies. No severe bleeding requiring blood transfusion or re-operation was observed in this study. The results showed no statistically significant difference between patients who continued treatment with antithrombotic therapy compared with patients having no antithrombotic treatment regarding sub graft hematomas or graft take. Continuing antithrombotic monotheraphy with acetylsalicylic, clopidogrel, warfarin or fish oil in relations to cutaneous surgery do not seem to increase risk of haematoma or graft lost.
This study does not have any comparison patient group
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biosift-nli
Soldiers at the base have set up tents , beds and toilets . Refugees would be placed more than 2 miles from detainees . Comment:
Soldiers at the base have set up tents , beds and toilets . Refugees would be placed more than 2 miles from detainees . No current indication of a `` mass migration '' from Haiti .
0not-entailed
doc-nli
(3) Maintenance of the Veterans Administration hospital system, with no impairment in the high quality of medical and hospital service; (4) Priority of hospitalization for the service-connected disabled, and the privilege of hospital care when beds are available for the non-service-connected illness of veterans who are sick and without funds or unable to procure private hospitalization;
This text is about medical facilities.
1entailed
Pol_NLI
Who is an American Tibetologist?
American Tibetologist Elliot Sperling has argued in favor of a recent tendency by some authors writing in Chinese to revive the term Tubote (simplified Chinese: 图伯特; traditional Chinese: 圖伯特; pinyin: Túbótè) for modern use in place of Xizang, on the grounds that Tubote more clearly includes the entire Tibetan plateau rather than simply the Tibet Autonomous Region.[citation needed]
1entailed
glue/qnli
Thomas climbed that place.
Someone or something did not change physically .
1entailed
recast/recast_verbcorner
not by the company ... as you voided your warrenty by installing custom roms
The voiding did not happen
0not-entailed
recast/recast_factuality
The Russian leader appointed Chechnya 's Prime Minister Ramzan Kadyrov to replace Alkhanov .
Russian is a geographical/political entity
1entailed
recast/recast_ner
FunTrivia Points: 30,249 Point Rank: # 46,193 of 1,844,059 players Points Today: 0, Yesterday: 0 cycloidmike's Team Points: 7,726 ( info ) For those who don't want a team but kind of want to be eligible for the team prizes. * Join Now Quizzes Authored: 0 Single Questions Accepted: 0 Quizzes Played: 67 Questions Correct: 524 / 750 (70%) Crosswords Played: Gold Member Feature Knockout Points: 0 (goto) Brains Collected: 0 (info) Monster Quizzes Taken: 51 (765 questions) Division: (1) The Newbies Mode: Normal User Rating: 1498 Last Graduation: None Games Played: 2
This text is about: game scores
1entailed
dataset_train_nli
What is not explicitly stated as true is considered false. Alan is rough. Bob is round. Bob is rough. Bob is nice. Bob is blue. Bob is big. Eric is rough. Eric is nice. Eric is big. Gary is red. If someone is nice and round and blue then they are red. If someone is rough and young and red then they are blue. If someone is red and kind and blue then they are green. If someone is rough and big and red then they are kind. If someone is kind and rough and big then they are round. If someone is young and nice then they are green. If someone is cold and round and rough then they are kind.
Gary is rough.
0not-entailed
ruletaker
~(((t&v)>(w|o)))
(~(t)>(o>((b|(t|e))>t)))
1entailed
logical-entailment
To compare the effects of sodium depletion and of angiotensin I converting enzyme inhibition on microalbuminuria in insulin dependent diabetes. Randomised, double blind, double dummy parallel study of normotensive diabetic patients with persistent microalbuminuria (30-300 mg/24 h) treated with enalapril or hydrochlorothiazide for one year after a three month, single blind placebo period. Diabetic clinic in a tertiary referral centre. 10 diabetic patients with low microalbuminuria (30-99 mg/24 h) and 11 with high microalbuminuria (100-300 mg/24 h). 11 subjects (six with low microalbuminuria, five with high microalbuminuria) were given enalapril 20 mg plus placebo hydrochlorothiazide once daily and 10 (four with low microalbuminuria, six with high microalbuminuria) hydrochlorothiazide 25 mg plus placebo enalapril once daily. Monthly assessment of urinary albumin excretion and mean arterial pressure; plasma active renin and aldosterone concentrations and renal function studies at 0, 6, and 12 months. Median urinary albumin excretion decreased from 59 (range 37-260) to 38 (14-146) mg/24 h with enalapril and from 111 (33-282) to 109 (33-262) mg/24 h with hydrochlorothiazide (analysis of variance, p = 0.0436). During the last three months of treatment with enalapril five patients had persistent normoalbuminuria (2-3 times below 30 mg/24 h), five low microalbuminuria, and one high microalbuminuria; in the hydrochlorothiazide group one had normoalbuminuria, three low microalbuminuria, and six high microalbuminuria (chi 2 test = 6.7; p = 0.03). Mean arterial pressure did not differ before (98 (SD 7) with enalapril v 97 (9) mm Hg with hydrochlorothiazide) or during treatment (88 (7) with enalapril v 90 (7) mm Hg with hydrochlorothiazide (analysis of variance, p = 0.5263)). Glomerular filtration rate did not vary. The aldosterone to active renin ratio was decreased by angiotensin I converting enzyme inhibition and increased by sodium depletion, showing treatment efficacy. Angiotensin I converting enzyme inhibition by enalapril effectively reduces microalbuminuria in normotensive diabetic patients whereas hydrochlorothiazide is not effective. Changes in blood pressure and activity of the renin-angiotensin-aldosterone system may contribute to these different effects.
This study has a cohort study or clinical trial
1entailed
biosift-nli
India has run its first Light Detection and Ranging (LiDAR)-based offshore wind survey at the Gulf of Khambhat in Gujarat, according to the National Institute of Wind Energy. The Indian Ocean is a key region for renewable energy development as it holds vast amounts of potential energy. In October 2015, the government had announced The National Offshore Wind Energy Policy to establish the policy framework for tapping the offshore wind potential in the country. Eight possible development areas off the shores of Gujarat and Tamil Nadu were identified.
India has run its first Light Detection and Ranging (LiDAR)-based offshore wind survey at the Gulf of Khambhat in Gujarat, according to the National Institute of Wind Energy. The Indian Ocean is a key region for renewable energy development as it holds vast amounts of potential energy. Eight possible development areas off the shores of Gujarat and Tamil Nadu were identified.
1entailed
doc-nli
Afghanistan would be a great place for Megan to go and start up a soccer team and empower all those oppressed women. Since the US thing isn't working out for her
This text is hate speech.
0not-entailed
Pol_NLI
What happened to the Sands Atlantic City a year after it closed?
The following year, the resort was demolished in a dramatic, Las Vegas styled implosion, the first of its kind in Atlantic City.
1entailed
glue/qnli
Andrew twanged to Samuel how to hirtle.
Something touched another thing .
0not-entailed
recast/recast_verbcorner
I was able to cancel it but only after paying a $ 50 fee ( which the staff person who signed me up stated I would not have to pay if I had proof of moving ) and being spoken to in a very belittling manner .
The speaking did not happen
0not-entailed
recast/recast_factuality
The International Committee of the Red Cross says 15 people have died in ethnic clashes around the western Ivory Coast town of Duekoue .
Ivory Coast is a location
1entailed
recast/recast_ner
With new restaurants opening regularly, it could take a few lifetimes to try everything once. That said, mixing the region’s hottest new flavors with a serving of classic staples is the best recipe for a true Twin Cities Taste. Search our restaurant listings for whatever feels right tonight. For corrections and additions, email [email protected].
This text is about: food and dining
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dataset_train_nli
What is not explicitly stated as true is considered false. Bob is cold. Dave is big. Erin is rough. Fiona is quiet. If Bob is young then Bob is white. White people are young.
Fiona is quiet.
1entailed
ruletaker
(o&c)
(g|~((c&d)))
0not-entailed
logical-entailment