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In gas chromatography, to achieve the separation of analytes with very different volatility, one should use:
A temperature gradient elution.
A gradient concentration elution.
An isothermal elution.
Pharmacology
An isocratic elution.
136
2
3b9018bb-f887-4d81-bd49-42fbea2d3c5c
2020
The alkaline error that a certain selective proton electrode presents at a pH >12 implies that:
The measured pH is always higher than the actual one.
The measured pH is always less than the actual one.
The concentration of protons found in the solution is less than the actual one.
Pharmacology
The measured pH may differ from the actual value, and could be higher or lower.
137
1
7c7993f2-d9d7-47a6-b941-2cc4f5558485
2020
To minimize chemical interferences in flame atomic absorption spectrometry, one could:
Add chelating agents to promote atomization.
Lower the temperature of the flame.
Use hollow cathode lamps that avoid this type of interference.
Pharmacology
Use very high resolution monochromators to discriminate the interferences of the element to be determined.
138
2
a1387f33-0139-462b-9998-052157d2559f
2020
Indicate which of the following answers, related to the absorption of electromagnetic radiation, is false:
The absorbance measured at a certain wavelength is directly proportional to the concentration of the absorbing substance.
The absorbance measured at a specific wavelength is directly proportional to the optical path.
Absorbance is the inverse of transmittance.
Pharmacology
The absorptivity or absorption coefficient is a constant characteristic of the wavelength.
139
4
79471f9e-8c8e-453f-abfb-c39910d7e88e
2020
In which of the following processes is the quantum spin number of an excited electron inverted, resulting in a change in the multiplicity of the molecule?:
Internal conversion.
Vibrational relaxation.
External conversion.
Pharmacology
Crossing between systems.
140
3
491008bc-7daf-4d46-9167-a3314ccecb5e
2020
In what type of liquid chromatography is there no chemical interaction between the solute and the stationary phase?
Reverse phase partition chromatography.
Normal phase partition chromatography.
Ion exchange chromatography.
Pharmacology
Size exclusion chromatography.
141
3
450cdab1-12fb-4ad5-9ca1-8c938b34d9eb
2020
Mass spectrometry is an analytical technique with great potential that cannot be coupled with the following equipment/instrumental techniques:
Gas Chromatography (GC).
High Performance Liquid Chromatography (HPLC).
Infrared absorption spectrometry (IR).
Pharmacology
Plasma Emission Spectrometry (ICP).
142
4
cfd29f4d-66cc-4a51-ad6b-cec7a9f27c41
2020
In a closed system consisted of a single component, in thermal and mechanical equilibrium, with P-V work only, what is the phase equilibrium condition?
The chemical potential of one of the phases must be maximum.
The chemical potential of one of the phases must be minimal.
The chemical potential should be zero in all phases.
Pharmacology
The chemical potential should be equal in each phase of the system.
143
3
7d79c85d-a83a-4544-b551-114b419e34d8
2020
When forming an ideal solution from its components, at constant T and P, the volume of the mixture:
It is always zero.
It is always negative.
It can be positive or negative but never zero.
Pharmacology
It is always positive.
144
2
510c9648-87a7-4690-bb3d-3899c75a3d12
2020
If the pressure remains constant and the temperature range is narrow, it can be stated that for an exothermic reaction, the equilibrium constant:
It is independent of temperature.
It only varies with temperature if the reaction is heterogeneous.
Decreases as the temperature increases.
Pharmacology
It increases as the temperature increases.
145
4
db733233-7587-4ab9-ab4f-2a9665a7fee0
2020
The units of the rate constant for a simple reaction:
They depend on the pressure of the reaction.
They depend on the temperature of the reaction.
They are the same for all reactions.
Pharmacology
They depend on the order of the reaction.
146
3
a958d930-7c24-4b56-a49f-6f617ee2fac3
2020
Which of the following toxins can cause malignant pleural mesothelioma after occupational exposure?:
Asbestos.
Aluminum powder.
Coal powder.
Pharmacology
Arsenic.
147
2
0a61360a-c3f1-4a35-b6c6-de4de7f75ffc
2020
What is the correct answer regarding cardiotoxicity induced by an overdose of local anesthetics?:
Very high doses of local anesthetics induce vasoconstriction and hypertension.
Very high doses of local anesthetics decrease cardiac excitability by inhibiting sodium channels.
Very high doses of local anesthetics affect cardiac contractility by inhibiting calcium channels.
Pharmacology
Local anesthetics do not cause cardiotoxicity, even if very high doses are used.
148
1
ca857d89-f4ba-415b-8e0b-46a2b939cff1
2020
The cyclohexane molecule can adopt different conformations. Indicate which of the following is the most stable:
The chair-like conformation.
Boat-like configuration.
The envelope-type conformation.
Pharmacology
The twisted boat-like configuration.
149
2
341859dc-6c16-45fd-a1d0-852dc4706015
2020
Which of the following definitions is correct to describe diastereomers?:
They are stereoisomers that have two or more chiral centers.
They are stereoisomers that are not mirror images.
These stereoisomers do not exhibit optical activity.
Pharmacology
These are stereoisomers that have equal specific rotations and opposite signs.
150
1
97432e7f-72b8-4c41-a7cd-307d11dcc772
2020
Which of the following statements is applicable to the bimolecular nucleophilic substitution reaction, SN2?:
Tertiary halogenated derivatives are more reactive than primary ones.
Brominated aliphatic compounds are less reactive than their corresponding chlorinated derivatives.
It is a concerted process that takes place in a single stage.
Pharmacology
Protic solvents increase the reaction rate.
151
4
5918bea3-32e2-432e-b28b-d5b9ba629e60
2020
According to Hückel's rule on aromaticity, which of the following compounds would be aromatic?:
Cyclooctatetraene.
Cyclobutadiene.
Cyclopentadiene.
Pharmacology
Pyridine.
152
3
6b4885ee-88c7-45e0-afe7-33c5030b3ad7
2020
According to the Molecular Orbital Theory, the bond order of the N2 molecule is 3, while that of the 𝐍𝟐 + cation is 2.5. Which N-N bond distance will be greater?
The one of N2 +.
The one of N2.
With just that information, it cannot be said.
Pharmacology
They will be equal.
153
2
a4eabd18-cb32-492c-9e2c-ca363668f0e2
2020
Diamond, graphite, and fullerenes are examples of:
Isotopes.
Allotropes.
Compounds.
Pharmacology
Isomers.
154
1
f49be315-1634-4b08-a42b-50e3f121f1c0
2020
The electron configuration [Kr] 4d105s25p4 corresponds to an element:
Transition metal.
Representative.
Of internal transition.
Pharmacology
From block d.
155
1
414dbe7d-40f4-479d-a337-250a74bb66fe
2020
In which of the following molecules does the central atom present sp3 hybridization?
NH3.
CO2.
BF3.
Pharmacology
PF5.
156
2
0cb9cb90-8e1c-4199-b8a5-c6cceac36a0c
2020
Which of the following molecules has a dipole moment equal to zero?:
H2O.
CO2.
SO2.
Pharmacology
NH3.
157
1
67c849e4-e457-41aa-afb7-95c12c2bba6f
2020
Age is a variable:
Ordered categorical.
Binary categorical.
Continuous quantitative.
Pharmacology
Discrete quantitative.
158
4
0dca1b2f-c847-4cca-8c88-0a521284642f
2020
Indicate which of these indexes are coincident in the following series of numbers: 0, 1, 3, 4, 4, 5, 8, 9:
The mean and the mode.
The mean and the median.
The mean, the median and the mode.
Pharmacology
The median and the mode.
159
3
aa333517-5212-47aa-ada1-30515c9d54e7
2020
Which of the following indices represents the change of one magnitude per unit of change of another magnitude?:
Relative frequency.
Absolute frequency.
Rate.
Pharmacology
Odds Ratio.
160
4
f60c6e88-4299-464a-a6c8-d768ae888be3
2020
The sensitivity of a diagnostic test for a certain disease represents the conditional probability that:
The result is negative if the subject has the disease.
The result is positive if the subject has the disease.
The result is negative if the subject does not have the disease.
Pharmacology
The result is positive if the subject does not have the disease.
161
1
1e521c15-ca75-49d7-bd41-bbe1a65f155c
2020
Which of the following groups of compounds can produce a toxic pathology of the skin characterized by the affectation of the sebaceous glands?:
Oxidizing agents.
Metals.
Alcohols.
Pharmacology
Chlorinated hydrocarbons.
162
3
1d5152a2-5d26-4b30-9e51-34877ac783f8
2020
A reaction to a medication that prolongs a patient's hospitalization is always considered:
Adverse event.
Unexpected adverse reaction.
Medication error.
Pharmacology
Severe adverse reaction.
163
3
94a33567-5273-4b29-9bef-0759acc9bc00
2020
To conduct a clinical trial with drugs, a favorable report from the following is mandatory:
Clinical Research Ethics Committee (CEIC).
Ethics Committee for Research (ECR).
Care Ethics Committee of the center where it will be carried out (CEA).
Pharmacology
Ethics Committee for Drug Research (CEIm).
164
3
52e47d39-9fca-47c7-aa1d-4ef315521894
2020
What is compassionate use of medications?
Use of medicines before their approval in Spain in patients suffering from a disease that cannot be satisfactorily treated with an approved medicine. This medicine must be subject to a marketing authorization application or clinical investigation.
Use of marketed drugs under conditions different from those authorized.
Use of drugs marketed in Spain for indications not included in the technical data sheet.
Pharmacology
Use of drugs authorized in other countries, but not authorized in Spain.
165
2
a3a95fb3-5f77-40f7-a1aa-9a0b645742c3
2020
Graft versus host disease begins when:
The mature T lymphocytes present in the graft sample react against the host's antigens.
The regulatory T lymphocytes present in the graft sample react against the host's antigens.
The mature T lymphocytes of the graft react against the antigens of the transplanted organ.
Pharmacology
The macrophages and neutrophils present in the graft sample react against the host's antigens.
167
2
be645989-2550-4153-b0dc-b353deb25254
2020
The adaptive response to intracellular bacteria mediated by CD4 T cells:
It is called Th17 and is induced by IL-17 and IFN-gamma.
It is referred to as Th1 and is induced by IL-12 and IFN-gamma.
It is called Th12 and is mediated by IL-12, IFN-gamma.
Pharmacology
It is called Th1 and is induced by IL-1 and IFN-gamma.
168
1
44bf7507-4b7f-4c6a-b6e0-0d7a157a7646
2020
Where does the activation of T lymphocytes specific for an antigen occur?
In any place where they encounter the antigen.
In the lymph nodes through contact with dendritic cells.
At the site of infection upon coming into contact with the pathogen.
Pharmacology
In the thymus through clonal selection.
169
1
abd747e1-21ac-43d4-89a2-f152915e7c8d
2020
What is the function of CD4+ Th17 lymphocytes?
Produce IL-1, IL-7 and induce an inflammatory response.
Produce IL-17 and induce an anti-inflammatory response.
Produce IL-17 and induce an inflammatory response.
Pharmacology
Produce IL-1, IL-7 and induce an anti-inflammatory response.
170
4
d773e7a9-7636-4102-be19-1bf9d922ec26
2020
What is the characteristic of memory T cells?:
They are quiescent and have increased reactivity to antigen exposure.
They are of constant proliferation without antigen and with increased reactivity to antigen exposure.
They are immortal and activate naive T cells to the replacement of the antigen.
Pharmacology
They are quiescent, with reduced reactivity to antigen exposure, and therefore responsible for autoimmunity.
171
2
722f2258-f83d-4d6c-9943-4bb6eb4d6c63
2020
Indicate the incorrect answer about the antigen receptor of T lymphocytes or TCR:
The chains that make up the TCR can be: alpha-beta or gamma-delta and are always expressed accompanied by CD3.
The hypervariable regions of the TCR undergo the phenomenon of somatic hypermutation in the lymph node.
The TCR-alpha-beta is generated by the somatic recombination of the V, D, and J segments (beta chain) and the V and J segments (alpha chain).
Pharmacology
In the rearrangement of the TCR, the phenomenon of allelic exclusion occurs: the correct rearrangement of a parental gene blocks the rearrangement of the other.
172
1
9e5523da-692f-4911-b860-b3ed546668db
2020
Which of the following associations between effector T lymphocytes, pathogen response, and effector mechanism is correct?:
TH2 lymphocytes --- allergen --- histamine release by mast cells.
T regulatory lymphocytes --- fungi --- release of antifungal peptides in the digestive tract.
TH17 Lymphocytes --- intracellular bacteria --- phagocytosis by dendritic cells.
Pharmacology
TH1 Lymphocytes --- extracellular bacteria --- - production of IFN-gamma for activation of NK cells.
173
2
33310e30-aa92-491b-9a4d-f62578843887
2020
Indicate the incorrect statement regarding chemokines:
CXCL13 determines the entry of follicular helper T lymphocytes (THF) into lymphoid follicles.
CXCR5 directs the movement of B lymphocytes through the T zone to the lymphoid follicles of the lymph node.
CCR5 directs the migration of naive T lymphocytes in the paracortex of the lymph node.
Pharmacology
CXCL8 is a chemokine involved in the chemotaxis of neutrophils.
174
4
5440ae64-5c9f-4481-9e0b-b842f8d31114
2020
What does a TCR recognize?:
An antigenic peptide associated with a presenting molecule.
An antigen in its native form.
Molecular patterns on the surface of bacteria.
Pharmacology
An antigen of any nature, as long as it is expressed on the membrane of the antigen presenting cells.
175
2
01864017-21be-48e6-bdf5-9cc41ce2705a
2020
Which of these laws best follow the frequency distribution of a rare characteristic (π<0.05) randomly obtained and with replacement in very large samples (n≥100)?:
The Poisson Law.
The hypergeometric law.
The Kruger law.
Pharmacology
Norman's law.
176
2
d025e130-048c-4fa8-91b7-6cc8d8ee5eac
2020
Reactions in the germinal center:
They require the recruitment of neutrophils and macrophages.
They occur in the absence of T lymphocytes.
They are required for the maturation of the affinity of humoral responses.
Pharmacology
They are necessary for the differentiation into plasma cells that produce antibodies.
177
4
8b4fa762-c34e-4c01-bd74-4253202d3a80
2020
Which of the following non-fermenting gram-negative bacilli is oxidase negative?:
Acinetobacter baumanii.
Pseudomonas aeruginosa.
Moraxella catarrhalis.
Pharmacology
Burkholderia cepacia.
178
2
59e02930-82a9-4ed3-8646-a8d4821e06f7
2020
Which of the following modifications in the steroid structure increases the anabolic activity of androgen receptor agonists?:
Substitution of C19 with an ethyl.
Substitution of C2 with an oxygen.
Introduction of a bulky substituent at the 7-alpha position.
Pharmacology
Introduction of a bulky substituent at the 11-beta position.
179
1
8f6911d1-d748-49cb-ad89-5b65adeeafcb
2020
A drug with a very high octanol-water partition coefficient:
It will tend to accumulate in the body's adipose tissue.
It will be evenly distributed in all tissues of the body.
It will tend to accumulate in the blood plasma.
Pharmacology
It will tend to accumulate in the body's aqueous tissue.
180
2
e412c0df-463f-4365-92bc-a99fe827b465
2020
Regarding diabetes mellitus, indicate the correct answer:
Type 1 diabetes mellitus comes with hyperinsulinemia.
Type 2 diabetes mellitus is associated with HLA DR3, DR4, DQA1 antigens.
In type 2 diabetes mellitus, ketoacidosis is the first clinical manifestation of the disease.
Pharmacology
Type 1 diabetes mellitus has a sudden onset.
181
3
32fd297c-5f46-47f9-886f-a4da39e6b95d
2020
The deficiency of carbamoyl-phosphate synthetase results in an inhibition of:
The Cori cycle.
The urea cycle.
The cycle of tricarboxylic acids.
Pharmacology
The glucose-alanine cycle.
182
1
0c3eeeb4-ca36-4d9e-b36f-6ff0c588a90c
2020
Which drugs are used in the treatment of both HIV and hepatitis B?
Lamivudine and darunavir.
Lamivudine and tenofovir.
Tenofovir and darunavir.
Pharmacology
Telbivudine and darunavir.
183
1
f636414e-2001-4b29-87bd-4b8751c5756d
2020
What is the mechanism of action of rivaroxaban?
It is an activator of human tissue plasminogen.
It is a direct inhibitor of thrombin.
It is a direct inhibitor of activated factor X (Xa).
Pharmacology
It is an inhibitor of vitamin K synthesis.
184
4
f2477129-8627-4b5d-a98f-7c014dd6667f
2020
Which drug is used in breast cancer for its anti-HER2 action?:
Lapatinib.
Imatinib.
Vemurafenib.
Pharmacology
Crizotinib.
185
2
56b3d616-b049-4afc-a9c6-0e730755f4a3
2020
Regarding the chemical structure of hormones, which of the following hormones is an amine?:
Growth Hormone (GH).
Corticotropin-releasing hormone (CRH).
Prolactin.
Biology
Triiodothyronine (T3).
1
3
54061103-a110-400a-a805-119285d8b5a6
2024
The estrogens:
They reduce the deposition of fat in the breasts.
They stimulate the osteoclasts.
They stimulate the growth of the endometrium.
Biology
Plasma levels of LDL increase.
2
4
b6b851a8-3faf-4270-b851-596b79131e86
2024
In what situation is filtration reduced in blood capillaries?
When the oncotic pressure of the plasma increases.
When the capillary hydrostatic pressure increases.
When the arteriolar diameter increases.
Biology
When the net filtration pressure increases.
3
2
2812a4a6-b734-41e0-83f2-2709b9400872
2024
In the process of normal respiration, the changes in the various pressures that cause the inflow and outflow of air are essential. In this regard, the alveolar pressure must be higher than the atmospheric one.
At the beginning of inspiration.
At the end of the inspiration.
At the end of expiration.
Biology
In the middle phase of exhalation.
4
3
9f8c7ec5-2cd2-471b-9ec9-14b156c6d14d
2024
The cortisol:
Increases the use of glucose.
Activates the inflammatory response.
Increases lipolysis.
Biology
Reduces gluconeogenesis.
5
4
c421184e-36fb-4441-b636-e2c4d80fc4de
2024
The adenohypophysis or anterior pituitary secretes:
Human Chorionic Gonadotropin (HCG).
Oxytocin.
Thyroid stimulating hormone (TSH).
Biology
Gonadotropin-releasing hormone (GnRH).
6
4
61d1a6e2-a5e3-4353-bef3-34b355146c2b
2024
Which of these factors inhibits the secretion of prolactin?
Dopamine.
Sleep.
Stress.
Biology
Thyrotropin-releasing hormone (TRH).
7
2
9c009a3e-6403-4db6-9c8c-8d4e2fb1db22
2024
Which of these factors stimulates the secretion of antidiuretic hormone (ADH)?:
Ethanol.
Atrial Natriuretic Peptide (ANP).
Decrease in the osmolarity of the extracellular fluid.
Biology
Decrease in the volume of extracellular fluid.
8
3
65a3adca-a007-4515-b72c-9abc70c1acb9
2024
A decrease in the concentration of plasma calcium ion (Ca2+) induces:
The increase of the hormone calcitonin.
The decrease in the secretion of parathyroid hormone (PTH).
The increase in bone resorption.
Biology
The decrease in phosphate excretion.
9
4
4140d172-8053-442a-ab6d-050ba9b407b6
2024
Which of the following factors decreases metabolic activity?:
The dream.
The growth hormone.
Testosterone.
Biology
The intake of food.
10
2
13cecccc-aa3a-4d54-ac5f-b875b0859586
2024
The pacemaker activity of the cardiac sinoatrial node:
It is insensitive to vagal stimulation.
It depends on a spontaneous depolarizing current.
It is due to the inactivation of voltage-dependent sodium channels.
Biology
It is characterized by having a delay of 0.13 seconds.
11
1
fadf9f55-d103-4e76-a691-5577d76b85a3
2024
The cardiac output is equal:
To the difference between the end-diastolic volume and the end-systolic volume.
To the product of heart rate and blood pressure.
To the product of the heart rate by the systolic ejection volume.
Biology
The difference between the systolic volume at rest and the systolic volume during exercise.
12
4
94afa1a5-64e0-44be-a3d6-d5b67fca95e9
2024
In the cardiac cycle, the pressure in the left ventricle is higher than the aortic pressure during the phase:
Isovolumetric relaxation.
Isovolumetric contraction.
Rapid ventricular filling.
Biology
Rapid ventricular ejection.
13
3
d059b3e2-a7fc-4be0-84f9-91aaf8e6e8c5
2024
In which of the following segments of the circulatory system is the blood flow velocity lowest?:
Arterioles.
Large caliber arteries.
Capillaries.
Biology
Large caliber veins.
14
4
164fc285-d03b-486e-8dcb-63243408cb3d
2024
Which nerve carries baroreceptor information from the carotid sinus to the central nervous system?
Phrenic.
Vagus.
Hypoglossal.
Biology
Glossopharyngeal.
15
3
3b38f519-5704-4ba3-9f9d-c9ee3963520d
2024
The seminal fluid or seminal plasma:
It has a pH of 4.0.
Contains spermatozoa.
It forms in the seminiferous tubules.
Biology
Contains fructose.
16
3
d64f320a-1eb3-4637-a855-cda2c34b3bc1
2024
Sertoli cells synthesize:
Androgen binding proteins.
Testosterone.
Cholesterol.
Biology
Follicle-stimulating hormone (FSH).
17
2
5e82fba0-79ed-4589-b4ec-304f05ac0b64
2024
After menopause, plasma levels of: increase.
Progestogens.
Estrogens.
Gonadotropins.
Biology
Inhibins.
18
4
481341a1-b9be-451d-8b86-af2e92d2f031
2024
The activins:
They inhibit the secretion of luteotropic hormone (LH).
They stimulate the secretion of follicle-stimulating hormone (FSH).
They are ovarian steroids.
Biology
They inhibit the secretion of gonadotropin-releasing hormone (GhRH).
19
1
84621729-5cac-4c63-92b7-1711d67e7c5a
2024
During childbirth, the prostaglandins:
They uncouple the myometrial gap junctions.
They are secreted by the corpus luteum.
They stimulate myometrial contraction.
Biology
They inhibit the effects of oxytocin.
20
4
90f26b1e-5798-4ca3-93b7-bd7b6912a998
2024
Which of the following mediators reduce food intake by inducing satiety?:
Orexins A and B (hypocretins).
CART (cocaine and amphetamine regulated transcript) and α-MSH (melanocyte-stimulating hormone).
Agouti-related protein (AgRP) and endocannabinoids.
Biology
Endorphins.
21
1
3820c06d-3b2a-4c85-b69d-d7cbf46dd080
2024
We can affirm the following about the complex migratory motors:
They start in the small intestine with digestion and continue to the large intestine.
They are segmental contractions from the esophagus to the rectum caused by ingestion.
They occur in the stomach every 9-10 minutes while it is full.
Biology
They are stimulated by motilin.
22
3
afcccf21-0c16-4289-b7da-5c8628871bb8
2024
Regarding salivary secretion and its regulation:
The kallikrein has vasoconstrictor effects.
The optimum pH of saliva for the digestive action of ptyalin is 8 or higher.
Bradykinin is a vasodilator substance.
Biology
The ductal epithelium of the salivary glands absorbs bicarbonate ions.
23
4
94952764-4bbe-4a19-be12-79f17a4bc715
2024
The secretion of hydrochloric acid is inhibited by:
Acetylcholine.
Sympathetic stimulation.
Histamine.
Biology
Gastrin.
24
1
14905b6d-23b4-4c3f-98ca-b1b24988b414
2024
Which substance uses the same sodium-dependent cotransporter (SGLT1) as glucose in its intestinal absorption in the apical membrane?:
Galactose.
Glutamine.
Fructose.
Biology
Sucrose.
25
2
0ab5fc59-1f06-4722-a347-2be76e058fcf
2024
In relation to the self-regulation of renal blood flow, it is TRUE that:
The renal blood flow is constant regardless of the functioning of the circulatory system.
When the blood pressure has values between 90 and 180 mm Hg, the renal blood flow is maintained within physiological limits.
The hydrostatic pressure in the glomerular capillaries is independent of the values of arterial tension.
Biology
Any blood pressure value ensures renal blood flow.
26
1
3d1ed9b0-4a81-494d-a89c-83ac6950bc0f
2024
Regarding the renal management of sodium, indicate the statement that you consider TRUE:
Aldosterone regulates the reabsorption of sodium in the nephrons.
The reabsorption of sodium in the nephrons is done by exchanging it for potassium.
The reabsorption of sodium is constant throughout the entire nephron.
Biology
The reabsorption of sodium is regulated exclusively in the proximal tubule.
27
2
40e216ef-ad5c-4dd8-900a-dfcafb09b32f
2024
In relation to the concentration of solutes in different tubular segments of the nephron, it is TRUE that:
The concentration of calcium increases in the distal tubule through secretion under the influence of parathyroid hormone (PTH).
The concentration of glucose, proteins, and amino acids decreases in the proximal tubule.
The concentration of sodium and potassium in the proximal tubule is regulated by aldosterone.
Biology
The concentration of sodium, potassium, and chlorine is virtually undetectable in the Henle's loop.
28
1
a87ffa9a-5b5b-4a35-b4a6-2d002cd833d2
2024
Regarding the tubulo-glomerular feedback or glomerulo-tubular balance, indicate the statement that you consider false:
The macula densa is the sensor of this physiological response.
It is a mechanism to regulate the glomerular filtration rate based on signals coming from the renal tubules.
It implies that an increase in the tubular flow rate causes a decrease in the glomerular filtration rate.
Biology
This implies that an increase in the glomerular filtration rate causes a decrease in tubular reabsorption.
29
3
b6bb24f2-9376-45b7-8dc3-91a6d68ca72f
2024
In relation to the so-called countercurrent multiplier mechanism present in the nephrons, it is TRUE that:
The ascending branch of the Henle's loop actively transports water to the renal medullary interstitium.
The osmolarity of the human renal medulla can reach 3,000 mOsm/L.
The antidiuretic hormone (ADH) regulates the excretion of water in the proximal tubule.
Biology
The descending limb of the Henle's loop is very permeable to water.
30
3
d0c8d6e6-7df9-4fce-b406-f298b10187b6
2024
The intrinsic pathway of coagulation begins with the factor:
X.
IX.
XII.
Biology
XI.
31
4
e2926d4b-cd8e-4f59-b032-8849d61f7b7e
2024
The iron transport protein in plasma is the:
Ferritin.
Apoferritin.
Hemosiderin.
Biology
Transferrin.
32
3
759e7460-33e0-465e-929f-4c8a0abb4fe7
2024
Only one blood type contains anti-A and anti-B agglutinins:
A.
0.
AB.
Biology
B.
33
1
ae92345f-ca82-4004-a40c-192610bb3b14
2024
The production of thymidine phosphate in hematopoiesis depends on:
Castle factor and vitamin B12.
Erythropoietin.
Vitamin B12 and folic acid.
Biology
Vitamin B6 and ferritin.
34
4
cc52cb20-615f-4137-9579-715bc46f0249
2024
In relation to the tissue PO2, only one of the following statements is true:
It depends on the transport of O2 and its usage rate by the tissues.
It depends exclusively on the transport of O2.
It self-regulates according to its concentration.
Biology
It is not related to the metabolic rate of the tissue.
35
2
6bc84a27-272a-41ce-9a2c-40d3770d39a2
2024
It is called "expiratory reserve volume":
To the volume of air that remains in the lungs after the most forced expiration.
To the maximum additional volume of air that can be exhaled through a forced exhalation after the end of a normal tidal volume exhalation.
To the residual volume plus the tidal volume.
Biology
To the volume of air that is inhaled or exhaled in each normal breath.
36
1
64950c0e-927c-452e-9bb3-07aa7a6e5c5e
2024
We define physiological dead space as:
The tidal volume minus the alveolar volume.
The volume of gas that fills the conducting airways.
The perfusion volume minus the tidal volume.
Biology
The total volume of gas in each breath that does not participate in the gas exchange.
37
3
b265ff88-8f9e-4e6b-ab4c-454fae92f34c
2024
The Hering-Breuer reflex is triggered by mechanoreceptors located in:
The diaphragm and the intercostal muscles.
The lungs.
Cerebral arteries.
Biology
The heart.
38
1
7e34cfb1-6c09-4754-b216-0315541c6e41
2024
The minute respiratory volume is equal to:
The tidal volume multiplied by the respiratory rate per minute.
The tidal volume multiplied by the lung capacity per minute.
The total lung capacity multiplied by the residual volume per minute.
Biology
The inspiratory capacity multiplied by the respiratory frequency per minute.
39
2
054bd2cf-13d5-4a27-a092-334295553f10
2024
Which of the following is the direct stimulus for the neurons of the chemosensitive area of the bulbar zone regulating respiration?:
Proton concentration.
PO2.
Concentration of HCO3-.
Biology
PCO2.
40
2
d6f68bbf-7348-4086-8711-a8caf61f316b
2024
The cells that form the optic nerves derive from the neuroectoderm of the:
Diencephalon.
Metencephalon.
Telencephalon.
Biology
Myelencephalon.
41
2
baabcb1b-39a0-452d-adca-e8e80bb81f61
2024
What is the unique property that distinguishes stem cells from cellular progenitors?
Its multipotentiality.
Its unlimited self-renewal capacity.
Its high rate of proliferation.
Biology
Its clonogenicity.
42
1
effed3e0-e643-405b-a0a1-51b5edef5410
2024
The Notch/Delta/Jagged molecular pathway receives and transduces signals of nature in cells:
Paracrine.
Autocrine.
Endocrine.
Biology
Juxtacrine.
43
3
cc15732d-f0a8-4e63-a405-8c96016745e2
2024
In which region of the embryo do definitive intraembryonic hematopoietic stem cells appear?:
In the aorta-gonad-mesonephros (AGM) region.
In the posterior intestine.
In the endocardium.
Biology
In the cardinal veins.
44
2
838dc2ed-cfe4-42ad-9a83-dbd203b5cc88
2024
Where are the stem cells and progenitors of keratinocytes found?:
In the epidermal stratum corneum.
In the basal epidermal layer.
In the dermis.
Biology
In the granular epidermal layer.
45
1
2c34eaea-cdb6-428a-8bdd-b03ff318c80a
2024
What determines the movement of a charged solute through a biomembrane?
The electrostatic potential exclusively.
The electrochemical gradient.
The concentration of specific transporters for that solute in the membrane.
Biology
The concentration gradient exclusively.
46
1
edf03b5d-47f7-46de-a0da-c22e6a9374ea
2024
Which compartment of mitochondria is chemically equivalent to the cytosol in terms of the small molecules and ions it contains?
The inner membrane.
The mitochondrial matrix.
All compartments show a very specialized content through selective transport.
Biology
The intermembrane space.
47
3
2a96a29d-3c0c-454b-b8f3-95e68627b612
2024
What type of vesicle mediates transport between the Golgi apparatus and lysosomes?
COPII-coated vesicles (COP, an acronym for "coat protein").
Coatamer-coated vesicles.
Clathrin-coated vesicles.
Biology
COPI-coated vesicles (COP, acronym for "coat protein").
48
4
67b97e05-f110-405d-a5d2-1367ae3820f3
2024
According to Mitchell's chemiosmotic theory, under which of the following experimental conditions will ATP synthesis be catalyzed?:
Coupling a proton gradient generator system to the activity of ATP synthase and in the presence of ADP and inorganic phosphate.
Expressing a carrier protein in the mitochondrial inner membrane that allows the movement of protons in favor of the gradient.
In the absence of the proteins of the electron transport chain, overexpressing ATP synthase and providing an excess of ADP and inorganic phosphate.
Biology
Adding uncoupling agents of the proton gradient to the mitochondria, such as DNP.
49
2
2148b4e2-2ea0-47c9-a40a-4928f7f921f9
2024
Through which receptor does adrenaline promote the degradation of glycogen in skeletal muscle?
A receptor with tyrosine kinase activity.
A G protein-coupled receptor.
An intracellular receptor.
Biology
A receptor with serine-threonine kinase activity.
50
1
b32365ee-67b8-4874-b433-47cbb2b2ee04
2024
Regarding the Na+/K+ pump of animal eukaryotic cells:
Transports Na+ into the cytosol.
Contributes to regulating the osmolarity (or tonicity) of the cytosol.
It is a Ca2+ dependent ATPase.
Biology
The transport of Na+ and K+ is in favor of the gradient.
51
1
15a587e0-0105-4d21-92c3-577d8421f987
2024