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{
"caption": "FISH analysis of Hone1 derived cells. A. Dual-color metaphase FISH (see METHODS) shows that in Hone1, parts of chr3 detected by chr3 painting probe (green) are included into different marker chromosomes (M1, M2 ...). The four underlined markers contain 3p21 as determined using the RP6-123I13 probe (red). B. After chromosome transfer, two additional normal chrs3 (N) are detected in #3/HONE1, clone 1. C. Identification of the marker chromosomes by four-probe metaphase FISH (see METHODS). Chr2, 3 and 12 painted parts are shown in red, blue and yellow, respectively. 3p21 RP6-123I13 signal is green. M1 has a translocation of a part of chr12. M2 carries a chr2 insertion. In M5, chr3 parts are translocated to a chr12 derived segment. D. Interphase FISH shows six RP6-123I13 probe signals (red) in the majority of the #3/Hone1 nuclei (blue DAPI staining). The sample was taken at the zero time point of in vitro propagation. This implies that the sample carries two supernumerary copies of the 3p21 (CER1) region, compared to four copies characteristic for Hone1. E. Interphase FISH, using the same probe, shows that #3/Hone1 cells have lost two supernumerary 3p21 copies after in vivo growth (tumor 2).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794251-6-1471-2407-7-21-2.jpg"
} | 000300 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Transmission electron micrographs illustrating VIBs and BTV distribution in BTV infected normal BSR and NS2 expressing cells. (A) BTV-10 infected BSR cells, (B) full-length NS2 expressing cells and(C) ΔNS2-1 expressing cells were analyzed by transmission electron microscopy 24 h p.i. Normal infection of BTV particles are amplified (A right panel) to indicate the newly synthesized particles (indicated by arrows). Bar = 0.5 μm.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794256-2-1471-2199-8-4-7.jpg"
} | 000301 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Intracellular sites of RNA synthesis in BTV infected cells. Co-localization of NS2 (green) and BrUTP labeled RNA (red) in BSR cells infected with BTV-10 (MOI of 1) 17 h p.i. The cells were treated with actinomycin D prior to immunostaining.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794256-3-1471-2199-8-4-4.jpg"
} | 000302 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Sub-cellular localization of BTV VP2, VP7 and VP3 in NS2 expressing or BTV infected BSR cells. (A) Distribution of VP2 (green) and NS2 (red) in BSR cells transfected with plasmids expressing VP2 and NS2 (middle) or infected with BTV-10 (right). (B) Localization of VP7 (green) and NS2 (red) in transfected (middle) and infected cells (right). (C) Expression of VP3 (green) and NS2 (red) in transfected (middle) and infected cells (right). (D) Co-localization of VP7 (green) and VP3 (red) in full-length NS2 expressing BSR cells co-transfected with plasmids expressing VP7 and VP3. BSR cells transfected with VP2, VP7 and VP3 were used as controls (left column in A, B and C).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794256-4-1471-2199-8-4-3.jpg"
} | 000303 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "NS2 IB does not associate with microtubule or vimentin. (A) BSR cells infected with BTV-10 (upper panel) at 5 h p.i or modified BSR cells expressing NS2 (lower panel) were treated with nocodazole (right column) to disrupt microtubule. NS2 (green) and microtubule (red) were monitored. Untreated cells labeled for microtubule and NS2 (left column) were used as controls. (B) NS2 expressing cells (right) and BSR cells 24 h p.i were labeled for vimentin (green) and NS2 (red). Un-transfected and uninfected cells labeled for vimentin (left) were used as control.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794256-5-1471-2199-8-4-2.jpg"
} | 000304 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "(A): HSIL (Pap Test) (100×); (B): Cervical intraepithelial neoplasia 2 (CIN2) on biopsy (40×).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794257-6-1742-6413-4-2-6.jpg"
} | 000305 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "External morphology of the honey bee antenna. The honey bee antenna was examined by scanning electron microscopy with different magnifications (A; x40, B; x150, C; x 300). Two proximal antennal segments (scape and pedicel) and the ten segments of the flagellum are indicated by arrows in A. Arrowhead in C indicates the position of electrode insertion for SEP recordings. The scale of each panel is shown by a white bar.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794319-6-ponep0000234pg001.jpg"
} | 000306 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "The apical 5 chambers view (panel A) shows the large VSD and right chamber dilatation. The velocity of flow trough the VSD is low (panel B). The RV sistolic pressure elevation is detected trough the tricuspid regurgitation velocities (panel C). RV = right ventricle, RA = right atrium, LV = left ventricle, LA = left atrium",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794404-0-1476-7120-5-2-2.jpg"
} | 000307 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "Intraoperatory findings (A and B): A- The transtricuspidic approach reveals the muscular obstructive band (arrow). B- The muscular band resected seemed an obstructive ring. TV = tricuspid valve. Post operatory findings: C- Paraesternal short axis view showing absence of right intraventricular obstruction as documented by color flow mapping.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794404-1-1476-7120-5-2-3.jpg"
} | 000308 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "The paraesternal minor axis view shows the large VSD, and a muscular band (arrow) witch shares the right ventricle into two chambers. The right ventricle outflow (RVOF) is free of lesions (panel A). Panel B shows the aliasing phenomena of color at the point of the muscular obstruction, with velocities and gradients represented in panel C.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794404-2-1476-7120-5-2-1.jpg"
} | 000309 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "Localization and kinetics of dephosphorylation of Borealin in cells that fail to divide. HEK293 cells stably expressing Borealin-GFP were exposed to blebbistatin (41 μM). The localization of Borealin and α-tubulin were analyzed by confocal microscopy. (A) Untreated, (B and C) Blebbistatin for 3.8 hrs (D and E) Blebbistatin for 45 min. (F) Borealin dephosphorylation and scheme of the experiment. WT-8 cells were synchronized in mitosis with nocodazole and then released from the block in the presence or absence of blebbistatin. Lysates were collected at the times indicated and analyzed by Western blotting. Western transfers were stripped and reprobed for β-actin as a loading control.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794407-4-1471-2121-8-5-6.jpg"
} | 000310 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "Measurements of intervertebral displacement resulting from the posterior to anterior (PA) mobilization and the prone press-up (PU) maneuver. The intervertebral (segmental) angle was measured as the angle formed by lines defining the endplates of adjacent vertebrae. Segmental lumbar displacement was defined as the difference in the intervertebral angle between the resting position (left) and intervertebral angle from the end range image (right). The arrow in Figure 2a identifies the hand of the examiner performing the PA mobilization.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794409-2-1471-2474-8-8-2.jpg"
} | 000311 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "Immunolocalization of uPA and tPA in preimplantation developing rat embryos grown in-vitro with and without the presence of 10 ng/ml EGF in the medium. (A, F, K, P), 2-cells. (B, G, L, Q), 4-cells. (C, H, M, R), 8-cells. (D, I, N, S), Morula. (E, J, O, T), Blastocyst. (A-E), uPA -EGF. (F-J), uPA +EGF. (K-O), tPA -EGF. (P-T), tPA +EGF.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794411-0-1477-7827-5-4-1.jpg"
} | 000312 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "Morphology of rabbit spermatozoa. Smears of ejaculated spermatozoa were air-dried and stained with PNA/DAPI. A. Spermatozoa from control rabbits. B. Spermatozoa from rabbits treated with 50 mg/kg/day miglustat for 8 weeks. Bar = 20 μm.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794412-1-1477-7827-5-1-2.jpg"
} | 000313 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "Effects of miglustat on morphology of spermatozoa from various mouse strains. Acrosomal and nuclear morphology of cauda epididymal spermatozoa from (A, B, C, G, H and I) control and (D, E, F, J, K and L) miglustat-treated mice from inbred mouse strains, (A and D) C57BR, (B and E) FVB/N, (C and F) BALB/c, (G and J) DBA/2, (H and K) AKR/J and (I and L) MA/MyJ. Acrosomes were stained with the monoclonal antibody Mab18.6 (green) and nuclei with propidium iodide (red). Drug administration was at 150 mg/kg/day. Bar = 10 μm.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794412-2-1477-7827-5-1-3.jpg"
} | 000314 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "Effects of miglustat on morphology of spermatozoa from interstrain hybrid mice. Acrosomal and nuclear morphology of cauda epididymal spermatozoa from miglustat-treated (A) C57BL/6 (15 mg/kg/day) and (B) FVB/N mice (600 mg/kg/day), and from (C, D, E and F) fourth-generation C57BL/6 × FVB/N hybrid mice (15 mg/kg/day). These drug-treated hybrid mice differed in their proportion of non-falciform acrosome-less spermatozoa. This proportion increases from C to F. Acrosomes were stained with the monoclonal antibody Mab18.6 (green), and nuclei with propidium iodide (red). Bar = 10 μm.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794412-5-1477-7827-5-1-6.jpg"
} | 000315 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "NIS expression in different tissues. A: Radioiodide accumulation in NIS-expressing human tissues (SG: salivary glands, T: thyroid, G: stomach) 2 hours after 99mTc-pertechnetate administration (5 mCi). B: Immunoblot analyses of human NIS expression in a Graves' thyroid (T), normal salivary glands (SG), and normal gastric mucosa (G). Total protein (50 μg) was electrophoresed into each lane; the nitrocellulose membrane was probed with 3 nM affinity-purified anti-human-NIS Ab as described in Materials and Methods. C-H: Immunohistochemical analyses of NIS expression in human iodide-concentrating tissues. C: Normal thyroid (original magnification: 400 ×), D: Graves' thyroid, strong basolateral NIS staining of the follicular epithelial cells (original magnification: 1,000 ×), E: Salivary gland (original magnification: 400 ×), F: Basolateral NIS staining in the salivary ductal cells (original magnification: 1,000 ×), G: Gastric mucosa (original magnification: 400 ×), H: Basolateral NIS staining of the gastric mucin-secreting cells (original magnification: 1,000 ×).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794416-0-1471-2407-7-5-1.jpg"
} | 000316 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "Immunohistochemical analysis of NIS expression in human gastrointestinal tract. a: normal esophageal squamous epithelium (haematoxylin-eosin/HE/staining, original magnification 100×) b: normal esophageal squamous epithelium: negative for NIS expression (original magnification 100×) c: Barrett mucosa (HE staining, original magnification 100×) d: Barrett mucosa, junctional and fundus-type columnar metaplasia: NIS positive staining (original magnification 100×) e: Barrett mucosa with intestinal metaplasia (HE staining, original magnification 100×) f: Barrett mucosa with intestinal metaplasia: negative for NIS expression (original magnification 100×) g: squamous cell esophageal carcinoma (HE staining, original magnification 100×) h: squamous cell esophageal carcinoma: NIS negative staining (original magnification 100×) i: gastric carcinoma – signet ring cell – (HE staining, original magnification 200×) j: gastric carcinoma – signet ring cell – negative for NIS expression (original magnification 200×) k: on the border of the gastric adenocarcinoma, adjacent \"normal\" extratumoral mucosa: faint, focal NIS expression (original magnification 100×) I: at 1 cm from gastric adenocarcinoma: definite focal NIS staining (original magnification 400×) m: far from the gastric adenocarcinoma: strong, linear NIS expression (original magnification 400×) n: gastric polyp (HE staining, original magnification 100×) o: gastric polyp: NIS positive staining (original magnification 100×) p: gastric polyp (HE staining, original magnification 200×) q: gastric polyp with colon-type metaplasia: NIS negative staining (original magnification 200×) r: small bowel adenocarcinoma (HE staining, original magnification 100×) s: small bowel adenocarcinoma: NIS negative staining (original magnification 100×) t: normal large bowel mucosa: NIS negative staining (original magnification 100×) v: colon polyp (HE staining, original magnification 100×) w: colon polyp: NIS negative expression (original magnification 100×) x: adenocarcinoma of the colon (HE staining, original magnification 100×) y: adenocarcinoma of the colon: negative for NIS expression (original magnification 100×).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794416-2-1471-2407-7-5-3.jpg"
} | 000317 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "Typical kidney tumor as found in p53E241X/E241X homozygous fish. (a) A stereoscopic view of the kidney tumor identified in a 2.5 month old homozygous p53E241X/E241X fish. (b-d) Hematoxylin-eosin staining of normal (b) and neoplastic (c) kidney of medaka. Note that the interstitial tissue is infiltrated with numerous hematopoietic cells destroying the normal architecture of renal tubules. The higher magnification shows the mixture of small lymphocytes with little cytoplasm and the plasmacyte-like cells with large basophilic cytoplasm (d).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794429-1-gb-2006-7-12-r116-5.jpg"
} | 000318 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "Radiation-induced p53 target gene induction and apoptosis. (a) Impaired IR-induced transactivation of target genes. Using semi-quantitative RT-PCR, induction of Mdm2 and p21 upon γ-irradiation can readily be observed in wild-type and heterozygous embryos, but is absent in animals homozygous for the p53 mutant allele. (b) Suppression of apoptosis in primary cultured cells. Primary cells derived from p53E241X/E241X and p53+/+ embryos were irradiated with 10 Gy of ionizing radiation and observed by time-lapse microscopy. The apoptotic cells from homozygous embryos with fragmented nuclei are indicated with arrows.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794429-3-gb-2006-7-12-r116-3.jpg"
} | 000319 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "Various tumors that developed spontaneously in p53 medaka knockouts. (a,b) The tumor that arose in the left gill of a p53E241X/+ fish with the lymphomatous infiltrate, consistent with the diagnosis of thymic lymphoma. (c,d) Adenocarcinoma found in the right gill of a p53E241X/E241X homozygous fish. (e,f) Retinoblastoma in the right eye of a p53E241X/E241X homozygous fish. Note the rosette-like structures throughout the tumor. (g,h) A germ cell tumor found in the anterior upper part of the peritoneal cavity of a p53E241X/E241X homozygous fish. All fish presented here died or were sacrificed at around 8 months of age. Arrowheads indicate tumors. Hematoxylin-eosin staining, original magnification: (b,d) 100×; (f,h) 10×.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794429-4-gb-2006-7-12-r116-6.jpg"
} | 000320 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "Isolation of tumor cells and tumor stroma from complete primary tumor sections. LCM microdissection was used to isolate tumor and stromal areas to generate artificial samples from complete primary tumor sections. (a,d,g) From primary tumor sections, areas comprising mainly (b) tumor cells or (e) tumor stroma, or (h) random circles were isolated using LCM. Samples with different tumor percentages were made by combining multiple tumor cell areas (b) and multiple tumor stroma areas (e) at varying ratios. Artificial samples for which the original tumor-stroma proportion was retained were made by isolation of multiple circled areas randomly distributed across the tumor section (h). See Materials and methods for more details. (c,f,i) Primary tumor sections after LCM of desired areas. The tissue sections shown here were colored using hematoxylin-eosin staining.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794430-3-gb-2006-7-12-r117-2.jpg"
} | 000321 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "Comparing segmentation results on the top and the side. Using a maximum projection, we show two portions of a three-dimensional image of an embryo fluorescently stained to label nuclei. (a) A projection along the optical axis, yielding a x-y image (the top of the embryo); (b) a projection perpendicular to that, yielding a x-z image (the side of the embryo). The nuclei on the top of the embryo appear well separated and distinct (a). Seen from the side, however, individual nuclei appear elongated along the z-axis due to limited axial resolution, which makes them more difficult to identify (b). The segmentation algorithm provided an accurate segmentation of nuclei (c) on the tops of embryo images, but (d) on the sides, a model was used to fine-tune the segmentation, resulting in a less accurate result.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794436-1-gb-2006-7-12-r123-3.jpg"
} | 000322 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "Comparing three-dimensional raw images to PointCloud representations. (a-c) Maximum projections of the three channels of a three-dimensional embryo image; (a) the nuclear stain (white); (b) a snail mRNA stain (red); and (c) an eve mRNA stain (green). Note the small bright speckles visible in all three channels at the same locations. These are outside the cytoplasm and are detected and removed by our image analysis algorithms. The small white rectangles show a region of interest that is displayed in (d-g). (d,e) The raw image of the nuclear stain (d) and the mRNA stains for eve and sna (e). (f,g) Two different renderings of the PointCloud derived from this image made using our visualization tool PointCloudXplore: (f) uses small spheres whose volumes are proportional to the measured volumes of the corresponding nuclei; (g) uses a Voronoi tessellation of the coordinates in the PointCloud. The arrows indicate the locations of the same three cells in each of the panels (d-g).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794436-3-gb-2006-7-12-r123-2.jpg"
} | 000323 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "Patterns of nuclear displacement from the PointCloud surface. The location of each nucleus with respect to a smooth PointCloud surface was mapped and averaged over the same cohort of embryos used in Figure 3 and displayed as a cylindrical projection. The map shows that the average apical (positive) or basal (negative) shift of nuclei forms a pattern that appears to correlate with cell fate and the expression patterns of blastoderm transcriptional regulators. Egg length (EL).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794436-4-gb-2006-7-12-r123-5.jpg"
} | 000324 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "Basal movement of nuclei during stage 5 in living Histone2A-GFP embryos. Two optical slices through the middle of a living embryo are superimposed. The red image was taken at the beginning of stage 5, whereas the green image was taken at the end. The bright line is the water-oil interface at the vitelline membrane, and was used to align the two images. All nuclei move inwards and elongate during stage 5. Anterior is to the left and dorsal is up.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794437-4-gb-2006-7-12-r124-5.jpg"
} | 000325 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "The distance and direction of nuclear movement in an individual living Histone2A-GFP embryo. Nuclei were tracked throughout stage 5, and the vector of their total motion was plotted on top of the image of the embryo at the beginning of stage 5. The color of the arrows is given by their length, short arrows being blue and long ones red. Vectors that are very different from nearby vectors were not used when generating the averaged plots in Figure 2. Anterior is to the left and dorsal is up.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794437-5-gb-2006-7-12-r124-11.jpg"
} | 000326 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "The X-box-containing genes Y69A2AR.2a, C02H7.1, F41E7.9, F32A6.2 and M04C9.5 are expressed exclusively within ciliated cells. Shown are green fluorescent protein (GFP) fluorescence images of the head (for example, amphid cell region) and tail (for example, phasmid cell region) regions of worms expressing transcriptional GFP reporters to the indicated genes. In all cases, expression is observed only within ciliated neuronal cells such as the amphid head cells and the phasmid tail cells.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794439-1-gb-2006-7-12-r126-2.jpg"
} | 000327 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Apoptosis of neutrophils in a healthy donor and in a patient with sepsis-induced acute respiratory distress syndrome (ARDS). (a) Apoptosis of neutrophils in a healthy donor. Wright's Giemsa staining of cytocentrifuge smear shows predominance of cells in apoptosis. Inset shows morphological detail of an apoptotic cell, with loss of chromatin fine granularity (condensation) and karyorrhexis. (b) Apoptosis of neutrophils in a patient with sepsis-induced ARDS. Wright's Giemsa staining of cytocentrifuge smear shows predominance of normal-looking cells. Inset shows morphological detail of a normal cell, with fine granularity of chromatin and normal lobulated nucleus. Magnifications ×200 (insets ×500).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794458-2-cc5090-1.jpg"
} | 000328 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "(Top left): Visualisation of the needle entering the anterior wall of the right internal jugular vein (RIJV) (longitudinal axis) (arrow). (Bottom left): Visualisation of the guidewire entering the venous lumen (arrow). (Top right): Visualisation of the needle entering the venous lumen (transverse axis). The black line behind the needle is the echo shadow (arrow). (Bottom right): Sagittal view of the neck, showing the catheter placed within the lumen (arrow). RCCA, right common carotid artery; REJV, right external jugular vein.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794469-0-cc5101-2.jpg"
} | 000329 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Thrombus visualised within the right internal jugular vein (RIJV) (arrow). The vessel could not be compressed. RCCA, right common carotid artery.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794469-1-cc5101-3.jpg"
} | 000330 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "The transducer is placed over the groove parallel and superior to the right clavicle (arrow).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794469-2-cc5101-1.jpg"
} | 000331 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Transoesophageal echocardiographic transgastric, cross-sectional view of the left ventricle at midpapillary muscle level with automated border detection (ABD). Endocardial border of the left ventricle, including the papillary muscles, was circumscribed manually to define the region of interest (blue line). ABD quantifies the cardiac chamber areas instantaneously by detecting the blood-tissue interface (red line), which results in a continuous, beat-to-beat left ventricular area curve (green line). Left ventricular end-diastolic area (LVEDA) was defined as peak of the left ventricular area during diastole. Left ventricular end-systolic area (LVESA) was defined as minimum left ventricular area during systole. Stroke area (SA) was defined as LVEDA – LVESA over the same cardiac cycle.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794488-0-cc5123-1.jpg"
} | 000332 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Transoesophageal echocardiographic transgastric, cross-sectional views of the left ventricle at midpapillary muscle level with automated border detection at baseline (top panel) and after volume expansion induced by passive leg raising manoeuvre (bottom panel). Left ventricular area curve was displayed with electrocardiogram and respiratory curve. Stroke area (SA) was defined as the difference between the end-diastolic area (LVEDA) and the end-systolic area. Maximal (SAmax) and minimal (SAmin) values of pulse pressure were determined over the same respiratory cycle. Respiratory variations in left ventricular SA (ΔSA) were then calculated using the following formula: ΔSA = [(SAmax - SAmin)/([SAmax + SAmin]/2)] × 100%. Passive leg raising manoeuvre induced a decrease in ΔSA and an increase in LVEDA. Gain was held constant throughout the protocol.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794488-3-cc5123-2.jpg"
} | 000333 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Development of infiltrates and inflammatory lesions in the vicinity of sunburn cells (SBCs) in patients with systemic lupus erythematosus (SLE). Haematoxylin eosin (H&E)-stained paraffin sections before and after irradiation with two minimal erythemal doses of ultraviolet B light (UVB). (a-c) Biopsies from a representative control, non-irradiated (a) and 1 (b) and 3 (c) days after irradiation. (d-f) Biopsies from a representative patient with increased influx of cells, non-irradiated (d) and 1 (e) and 3 (f) days after irradiation. Magnifications, ×100. (g) Graph showing semi-quantitative analysis of infiltrate in H&E sections before and up to 10 days after irradiation. Dotted lines indicate mean + two standard deviations of controls. ●, patients (P); ○, controls (C). No significant differences were present between patients and controls on any time point. (h) Inflammatory lesion in a patient with SLE in the vicinity of SBCs 3 days after irradiation. Inflammatory lesions were defined as the presence of category 5 (see Materials and methods) vessel(s) in the dermis, with inflammatory cell infiltration of the epidermal layer coinciding with marked local hydropic degeneration of the basal layer of the epidermis. Insert shows magnification of area with accumulating SBCs. Magnification, ×100. White arrowheads indicate SBCs, and black arrowheads indicate hydropic degeneration.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794497-0-ar2051-2.jpg"
} | 000334 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Presence of apoptotic cells and phagocytosis by macrophages comparing controls and patients with or without infiltrates. (a) Numbers of sunburn cells (SBCs) in patients with infiltrates, patients without infiltrates, and controls before and up to 10 days after irradiation. ■, patients with infiltrates (IP); ●, patients without infiltrates (P); ○, controls (C). Extensive phagocytosis of apoptotic keratinocytes by macrophages in the epidermis of patients with infiltrates. (b) Representative biopsy showing CD68 staining combined with haematoxylin staining using diaminobenzidine (DAB) for visualisation of CD68-positive cells. Magnification, ×400. Two macrophages that contain multiple phagocytic vacuoles (black arrows) are shown. One vacuole clearly contains an apoptotic cell (checkered arrow). (c) Representative biopsy showing CD68 staining using DAB for visualisation, combined with haematoxylin eosin staining. Magnification, ×400. White arrow indicates macrophages not involved in phagocytosis, and checkered arrows indicate eosinophilic particles that are being ingested by macrophages. UVB, ultraviolet B light.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794497-1-ar2051-5.jpg"
} | 000335 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Co-localisation of apoptotic keratinocytes and infiltrate in lupus erythematosus (LE) skin lesions. Sections of two representative LE skin lesions showing an area of local accumulation of apoptotic keratinocytes and local infiltration of inflammatory cells and hydropic degeneration of the epidermis. Arrowheads indicate apoptotic keratinocytes. Magnifications, ×40 (left panels) and ×200 (right panels).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794497-3-ar2051-3.jpg"
} | 000336 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Effect of HGF on skin fibrosis in TSK/+ mice. Skin fibrosis in dorsal skin from C57BL/6, pa/pa, and TSK/+ mice with or without treatment with HGF. Representative histologic sections stained with hematoxylin and eosin are shown (× 40). An asterisk indicates the subcutaneous loose connective tissue layer beneath the panniculus carnosus (arrow). HGF, hepatocyte growth factor; TSK/+, tight skin.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794503-2-ar2068-2.jpg"
} | 000337 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Effect of HGF on pulmonary changes in TSK/+ mice. Representative histologic sections stained with hematoxylin and eosin are shown (× 40). HGF, hepatocyte growth factor; TSK/+, tight skin.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794503-4-ar2068-4.jpg"
} | 000338 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Transfection of ATDC5 cells with wild type and mutant Ank. (a) Confocal microscopy of ATDC5 cells transiently transfected with M48T mutant cDNA. Left panel is phase-contrast image of right panel. All transfected cells showed a similar pattern of plasma cell membrane staining, indicating that even mutant Ank molecules were able to translocate to the plasma cell membrane. (b) ELISA assay results showing comparative levels of Ank protein expression in ATDC5 cell lysates versus lysates of independent clones of ATDC5 cells transduced with various ank constructs. All cells express endogenous Ank protein, but transduced cells also express protein derived from expression of transduced constructs. Data represent quadruplicate assays and are representative of results obtained from other independent clones for each transductant. *P ≤ 0.05. (c) WST-1 proliferation assay at day 7 of culture in ATDC5 cells transduced with empty vector and with various wild-type (WT) or mutant ank constructs. At days 7, 14, and 21, 7.5 μl WST-1 reagent was added directly to 150 μl cell medium and incubated for 1.5 hours at 37°C in 5% CO2. Results at all time points consistently exhibited no significant differences in the proliferation of mutant-transduced cells compared with untransduced cells or cells transduced with empty vector. n = 3.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794507-1-ar2072-1.jpg"
} | 000339 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Collagen type IV staining in healthy and arthritic synovial tissue. Collagen type IV was found in the lining layer of synovial biopsies from (a) healthy human subjects and (c) rheumatoid arthritis (RA) patients. Relative isotype controls are shown in (b,d). Double staining was performed to reveal the cellular origin of the type IV collagen. (e) Double staining was found in the lining layer. For a clearer picture, succeeding slices were stained with (f) CD55 or (g) collagen type IV. (h) Isotype control. Arrows indicate collagen IV, CD55 or double staining in the lining layer. (i) PCR results: top, collagen type IV mRNA expression in fibroblast-like synoviocytes from 10 RA patients and 11 healthy controls; bottom, β2-microglobulin (β2M) mRNA expression in the same samples.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794508-0-ar2073-3.jpg"
} | 000340 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Haematoxylin and eosin staining on healthy and arthritic synovial tissue. Haematoxylin and eosin staining was performed on synovial biopsies from (a) healthy subjects and (b) Rheumatoid arthritis patients. Arrows indicate synovial lining.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794508-4-ar2073-1.jpg"
} | 000341 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "IL-32 was abundantly expressed in the synovial tissues of rheumatoid arthritis patients. (a) In situ hybridization of the synovial tissues from rheumatoid arthritis (RA) patients. IL-32β was expressed in the synovial-infiltrated lymphocytes of RA patients. HE stain, hematoxylin and eosin stain. We examined the tissue samples from four RA patients, and show representative examples. (b) IL-32 expression of the synovial fibroblasts derived from four RA patients in response to human tumor necrosis factor alpha (hTNFα).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794509-0-ar2074-2.jpg"
} | 000342 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Effect of CF101 and prophylactic or therapeutic MTX treatment on AIA rats. Rats were injected subcutaneously at the tail base with 100 μl of a suspension composed of incomplete Freund's adjuvant and 10 mg/ml heat killed Mycobacterium tuberculosis. (a) Clinical score. Combined treatment with MTX (prophylactic treatment) + CF101 yield significantly lower values than treatment with each of the agents alone; also, all treatments yielded lower scores than control group. (b) The clinical score with combined therapeutic MTX treatment + CF101 was significantly lower than that in the other groups. (c, d) Morphopathological score. In AIA animals complete distruction of the cartilage and the bone, as well as severe inflammation in the hind paws, was noted. Treatment with a combination of MTX and CF101 preserved the normal features of the paw. AIA, adjuvant-induced arthritis; MTX, methotrexate.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794513-1-ar2078-1.jpg"
} | 000343 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Immunohistochemistry analysis of A3AR expression in paws from AIA rats. We conducted immunohistochemistry staining of paraffin-embedded sections of paw from MTX-treated, CF101-treated and MTX+CF101-treated AIA rats. MTX treatment induced receptor expression, and treatment with CF101 alone or in combination with MTX resulted in receptor downregulation. A3AR, A3 adenosine receptor; AIA, adjuvant-induced arthritis; MTX, methotrexate.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794513-4-ar2078-2.jpg"
} | 000344 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Comparison of immunohistochemical detection of activation markers. Analysis of representative areas of synovial tissue samples taken from patients with end-stage osteoarthritis (OA) or refractory rheumatoid arthritis (RA) is shown. Expression pattern and staining intensity of RA samples represent the stronger intensity of synovial inflammation when compared with OA samples. Magnification, ×400. FAP, fibroblast activation protein; MMP, matrix metalloproteinase.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794515-0-ar2080-5.jpg"
} | 000345 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Cell surface expression of fibroblast activation protein (FAP). Gene expression analysis is completed by immunohistochemical staining. FAP-specific staining was performed on synovial samples of five individuals of each entity (rheumatoid arthritis [RA] and osteoarthritis [OA]), demonstrating the stronger expression at the protein level in the inflamed synovia of patients with refractory RA. Magnification, ×100.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794515-1-ar2080-2.jpg"
} | 000346 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Immunohistochemical analysis of activation markers in synovial membranes of osteoarthritis. Phenotypic markers that are instrumental in extracellular matrix alteration are detectable only at a low level (MMP-1, CD44v7/8) in areas that are slightly FAP-positive. Magnification, ×400. FAP, fibroblast activation protein; MMP, matrix metalloproteinase.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794515-2-ar2080-3.jpg"
} | 000347 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Immunohistochemical analysis of activation markers in synovial membranes of rheumatoid arthritis. Expression of fibroblast activation protein (FAP) is accompanied by accumulation of activation markers (MMP-1 and MMP-13) and splice variants of CD44 (v3 and v7/8) that are known to correlate with the degree of inflammation and that are involved in extracellular matrix deposition. Magnification, ×400. MMP, matrix metalloproteinase.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794515-3-ar2080-4.jpg"
} | 000348 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Double-staining of fibroblast activation protein (FAP) and smooth muscle actin (SMA). Synovial tissue samples from patients with destructive rheumatoid arthritis were stained to demonstrate the simultaneous expression of both antigens. FAP-positive fibroblasts in the intimal synovial lining were coloured brown (DAB [3,3'-diaminobenzidin]). Coexpression of SMA is visualised in red (fast red). Magnification, ×400.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794515-4-ar2080-7.jpg"
} | 000349 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Immunohistochemical characterisation of fibroblast populations. Collected samples were snap-frozen, and sequential sections were stained for expression of Thy-1, fibroblast activation protein (FAP), or smooth muscle actin (SMA). Antigen-positive cells were identified by pink-brown colouration. Tissue samples of both entities, rheumatoid arthritis (RA) and osteoarthritis (OA), show distinct synovial fibroblast populations. Associated expression of SMA and FAP distinguishes myofibroblasts of the intimal synovial lining from Thy-1-positive fibroblasts or only SMA-expressing perivascular smooth muscle cells. Staining of anti-human FAP and anti-human SMA is more intense in RA tissue samples when compared with OA. Magnification, ×100.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794515-6-ar2080-6.jpg"
} | 000350 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "X-ray of a normal proximal femur, showing the intertrochanteric region (rectangle) used for sampling.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794534-6-ar2101-1.jpg"
} | 000351 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Immunohistochemical stain with the proliferation marker Ki-67.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794536-0-1742-6413-4-3-22.jpg"
} | 000352 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "HE stain. Histological section of the tumor with mainly spindled tumor cells and a dense eosinophilic intercellular substance.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794536-1-1742-6413-4-3-10.jpg"
} | 000353 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Air-dried Giemsa stained smear showing abundant granular metachromatic ground substance and a metachromatic stromal fragment.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794536-10-1742-6413-4-3-4.jpg"
} | 000354 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Ultrastructural image showing abundant tonofilaments in the cytoplasm.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794536-11-1742-6413-4-3-23.jpg"
} | 000355 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "HE stain. Histological section of the tumor with spindled and polygonal cells with distinct pleomorphism and dense eosinophilic cytoplasm.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794536-12-1742-6413-4-3-9.jpg"
} | 000356 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "HE stain. Histopathological specimen showing a cell dense tumor with eosinophilic ground substance.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794536-14-1742-6413-4-3-7.jpg"
} | 000357 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "HE stain. Histological section of the tumor showing pleomorphic tumor cells with central mitotic figure.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794536-15-1742-6413-4-3-15.jpg"
} | 000358 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Immunohistochemical stain with a pan-keratin AB.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794536-16-1742-6413-4-3-20.jpg"
} | 000359 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Immunohistochemical stain with a vimentin AB.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794536-17-1742-6413-4-3-21.jpg"
} | 000360 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "HE stain. Admixture of lymphocytes in histological section of the tumor.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794536-18-1742-6413-4-3-14.jpg"
} | 000361 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Air dried, Giemsa stained smear showing single spindle or polymorphic, polygonal cells with and group of benign ductal epithelial cells.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794536-19-1742-6413-4-3-1.jpg"
} | 000362 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Air-dried Giemsa stained smear with large metachromatic stromal fragment.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794536-2-1742-6413-4-3-5.jpg"
} | 000363 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Air-dried Giemsa stained smear central mitotic figure (in the center of the image).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794536-21-1742-6413-4-3-6.jpg"
} | 000364 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "HE stain. Histopathological section of the tumor with a dense infiltrate of atypical cells and an eosinophilic substance in between.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794536-22-1742-6413-4-3-8.jpg"
} | 000365 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "HE stain. Histological section from the tumor with fuzzy invasion border towards the fatty tissue.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794536-3-1742-6413-4-3-17.jpg"
} | 000366 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Air dried, Giemsa stained smear showing a mixture of spindle and polygonal cells in a granular metachromatic ground substance. One of the polygonal cells has an intranuclear vacuole.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794536-4-1742-6413-4-3-2.jpg"
} | 000367 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Immunohistochemical stain for actin which is positive in the tumor cells.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794536-5-1742-6413-4-3-19.jpg"
} | 000368 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "HE stain. Histological section of the tumor demonstrating invasion of spindled tumor cells in fatty tissue.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794536-6-1742-6413-4-3-18.jpg"
} | 000369 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "HE stain. Histological section from area demonstrating tumor cell invasion in surrounding fatty tissue.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794536-7-1742-6413-4-3-16.jpg"
} | 000370 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Air dried, Giemsa stained smear with polygonal tumor cells with dense bluish cytoplasm.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794536-8-1742-6413-4-3-3.jpg"
} | 000371 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "HE stain. Histological section of the tumor with spindled and polygonal tumor cells with distinct pleomorphism.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794536-9-1742-6413-4-3-11.jpg"
} | 000372 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Laser capture microdissection of neuroblast clusters. (a) Large cluster of neuroblasts in fetal adrenal glands at 19 weeks' gestational age (mounted hematoxylin and eosin stained cryosections), (b,c) unmounted hematoxylin and eosin stained fetal adrenal cryosections with a neuroblast cluster before and after microdissection (sample 2), and (d) the microdissected neuroblast cluster.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794547-0-gb-2006-7-9-r84-2.jpg"
} | 000373 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Identification of sympathetic neuroblasts and chromaffin cells in human fetal adrenal glands by immunohistochemical analysis. Sections of a human fetal (19 weeks) adrenal gland, adjacent to those used for laser capture retrieval of cells for mRNA extraction and gene expression profiling, were stained with (a) hematoxylin and eosin or antibodies directed against (b,f) TH, (c,g) CHGA, (d,h) BCL2, and (e,i) HNK1. Whereas the immunoreactivities of BCL2 and HNK1 are specific for neuroblasts, TH and CHGA expression is pronounced in chromaffin cells and weak in neuroblasts [8]. Stars indicate chromaffin cells (TH+, CHGA+, BCL2-, and HNK1-), either solitary or intermingled with neuroblasts. Panels a-e show a cluster of adrenal neuroblasts and panels f-i show cortical area within scattered chromaffin cells adjacent to the neuroblast cluster. Inserts in panels b-e (bars: 10 μm) correspond to the boxed areas in these panels (bars in panels a-i: 100 μm). BCL2, B-cell CLL/lymphoma 2; CHGA, chromogranin A; H&E, hematoxylin and eosin; HNK1, carbohydrate epitope; TH, tyrosine hydroxylase.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794547-5-gb-2006-7-9-r84-1.jpg"
} | 000374 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Representative sections of nasal mucosa fromewes 14 days post-inoculation with ovine or human B. parapertussis. (Hematoxylin and eosin stain, 400× magnification.) (a) Ewe inoculated with ovine strain. The epithelium has intact epithelial cells. The section lackssignificant infiltrates of inflammatory cells. (b) Ewe inoculated with human strain. The epithelium is covered by mucinous materialadmixed with neutrophils, eosinophils, necrotic cell debris, and seroproteinaceous fluid. Within the epithelium and lamina propria are moderate infiltrates of neutrophils (open arrowheads)and eosinophils (filled arrowheads). The lamina propria is moderately expanded by edema.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794550-2-gb-2006-7-9-r81-4.jpg"
} | 000375 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Identifying mutant shapes and textures. In each case, four images of each sample were quantitatively analyzed and images were adjusted using Adobe Photoshop auto levels for display only. Scale bars = 15 μm. (a) The unusual cell shape induced by an RNAi reagent against Myo3A in human HT29 cells is quantitatively distinguishable from wild-type control cells. (b) The unusual cell shape induced by an RNAi reagent against PTPN21 in human HT29 cells is quantitatively distinguishable from wild-type control cells. (c) The unusual actin texture induced by an RNAi reagent against DUSP19 in human HT29 cells is quantitatively distinguishable from wild-type control cells. The images are pseudocolored to show the actin staining texture. The biological basis of these morphological changes and the specificity of the RNAi reagents remain to be determined.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794559-1-gb-2006-7-10-r100-3.jpg"
} | 000376 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Testing experiment for the signal scaling approach. (a) The design of the test slide with positive spots shown as red spots and the five tested normalization window, indicated by red squares, for a given spot on the array, shown in blue. (b) Comparison of signal intensity before and after normalization using window size 9 on the testing experiment. The two images were computationally reconstructed from the signal files, either without or with normalization. (c) Density plots of signals in the local windows are shown superimposed. The distributions are more similar to each other after the signal normalization using the default window size 9. (d) Variation analysis for positive controls. Five out of six controls showed a decrease of variances after normalization.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_100-PMC1794587-0-gb-2006-7-11-r110-5.jpg"
} | 000377 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Expression of PGL34g-YFP in planta. A. Schematic representation of the construct used for plant transformation. The coding sequence of the yellow fluorescent protein (YFP) was inserted in the genomic sequence of PGL34, replacing the PGL34 stop codon. Boxes indicate coding regions. B. Western blot analysis of rosette leaves from homozygous T2 transgenic lines. PGL34-YFP was detected with anti-GFP antibodies. Proteins were visualized on the membrane by staining with amidoblack. Wt, wild type Arabidopsis plant protein extract. C. Yield estimation. Different amounts of total protein extracts from line 5.2 were subjected to SDS-PAGE in parallel with defined amounts of recombinant GST-GFP and chemiluminescent immunoblot signals were quantified. D. Detection of PGL34-YFP by fluorescence microscopy. YFP fluorescence was detected in leaves, cotyledons and roots by illuminating the seedlings with UV light. Scale bars: 0.5 mm. E. Subcellular localization of PGL34-YFP in leaves was determined using confocal laser scanning microscopy. Scale bars: 10 μm.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_101-PMC1796540-2-1472-6750-7-4-3.jpg"
} | 000378 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Transient expression of truncated PGL34-GFP fusions in protoplasts. A. DNA constructs encoding fragments of or full length AtPGL34 coding sequence fused to GFP. The transit peptide of PGL34 is shaded. The Kyte and Doolittle hydropathy plot of PGL34 is shown and domains with higher hydropathy scores (H1–H3), as well as a domain conserved among PAP-fibrillin proteins (black bar), are indicated. B. Fluorescence of the GFP fusion proteins (GFP) was detected in transformed protoplasts by confocal laser scanning microscopy. Arrows indicate strong GFP signals overlapping with weak chlorophyll autofluorescence signals (chlorophyll). Merge: overlap of chlorophyll and GFP signals. Scale bars: 5 μm. C. Detection of GFP fusion proteins in transformed protoplasts by immunoblotting using anti-GFP antibodies. D. Cotransformation of protoplasts with full length and truncated PGL34. Protoplasts coexpressing PGL34-CFP and PGL341–133-YFP, PGL341–170-YFP or PGL341–290-YFP were analysed by confocal microscopy. CFP fluorescence (CFP) and YFP fluorescence (YFP) were monitored sequentially using distinct excitation wavelengths and detection windows. Chlorophyll: chlorophyll autofluorescence, merge: superposition of YFP and CFP signals (green and red pseudocolours, respectively). Bar length: 5 μm.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_101-PMC1796540-5-1472-6750-7-4-2.jpg"
} | 000379 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Strong (A) and weak (B) XIAP expression (red) in melanoma using ×10 magnification, employing S100 (green) to define tumor and DAPI (blue) to define nuclei. Strong (C) and weak (D) XIAP expression are shown using ×60 magnification. The strong spot corresponds to an AQUA score of 52.91 and the weak spot to a score of 21.85.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_101-PMC1796544-0-1479-5876-5-6-2.jpg"
} | 000380 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Anomalous origin on the right subclavian artery. Serial images from a helical CT scan of the superior mediastinum, cranial to caudal. Notice the large enhancing vascular structure posterior to the esophagus (*). On the more caudal images, a direct origin of this vessel from the aortic arch, distal to the origin of the left subclavian artery, is noted.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_101-PMC1796545-1-1749-7922-2-1-5.jpg"
} | 000381 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Anomalous origin on the right subclavian artery. Serial images from a helical CT scan of the superior mediastinum, cranial to caudal. Notice the large enhancing vascular structure posterior to the esophagus (*). On the more caudal images, a direct origin of this vessel from the aortic arch, distal to the origin of the left subclavian artery, is noted.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_101-PMC1796545-10-1749-7922-2-1-6.jpg"
} | 000382 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "53-year old Korean man with a remote history of facial trauma, and a four day history of diplopia and right third cranial nerve palsy. Lateral digital subtraction angiogram, right internal carotid artery. During this early phase, there is visualization of the cervical and intracranial carotid artery; in addition, early filling of the cavernous sinus (arrow) is noted.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_101-PMC1796545-11-1749-7922-2-1-1.jpg"
} | 000383 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "36-year old woman, s/p motor vehicle collision. On admission, an angiogram demonstrated a pseudoaneurysm of the thoracic aorta, as well as a grade 3 (pseudoaneurysm) of her left internal carotid artery. Her aorta was repaired immediately; on follow-up angiography of her carotid injury, her pseudoaneurysm had progressed and there was significant narrowing of the adjacent internal carotid artery. Digital subtraction angiogram of the left internal carotid artery, s/p stent placement. A 6 mm × 47 mm Magic Wallstent (Boston Scientific, Watertown, MA) was placed. Notice the immediate and nearly complete resolution of the pseudoaneurysms.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_101-PMC1796545-12-1749-7922-2-1-8.jpg"
} | 000384 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "25-year old woman involved in a rollover motor vehicle collision. On admission to the hospital, a screening four-vessel angiogram revealed a pseudoaneurysm of the left vertebral artery at the level of the C1–C2 disc space. Follow-up angiography performed 7 days later revealed enlargement of the pseudoaneurysm and concomitant narrowing of the vertebral artery. Due to the tortuosity of the vertebral artery, stent placement was not deemed a viable option and the vertebral artery was embolized. Unsubtracted image demonstrating coils placed distal and proximal to the pseudoaneurysm, trapping the diseased segment of vessel.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_101-PMC1796545-2-1749-7922-2-1-11.jpg"
} | 000385 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Anomalous origin on the right subclavian artery. Serial images from a helical CT scan of the superior mediastinum, cranial to caudal. Notice the large enhancing vascular structure posterior to the esophagus (*). On the more caudal images, a direct origin of this vessel from the aortic arch, distal to the origin of the left subclavian artery, is noted.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_101-PMC1796545-3-1749-7922-2-1-4.jpg"
} | 000386 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "53-year old Korean man with a remote history of facial trauma, and a four day history of diplopia and right third cranial nerve palsy. Anteroposterior digital subtraction angiogram, right internal carotid artery. Mid-arterial phase image demonstrates early filling of the cavernous sinus with filling of the contralateral inferior petrosal sinus (arrow).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_101-PMC1796545-4-1749-7922-2-1-3.jpg"
} | 000387 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "25-year old woman involved in a rollover motor vehicle collision. On admission to the hospital, a screening four-vessel angiogram revealed a pseudoaneurysm of the left vertebral artery at the level of the C1–C2 disc space. Follow-up angiography performed 7 days later revealed enlargement of the pseudoaneurysm and concomitant narrowing of the vertebral artery. Due to the tortuosity of the vertebral artery, stent placement was not deemed a viable option and the vertebral artery was embolized. Lateral digital subtraction angiogram, left vertebral artery. Notice the pseudoaneurysm arising from the distal vertebral artery (arrow), and the adjacent vertebral artery narrowing.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_101-PMC1796545-5-1749-7922-2-1-10.jpg"
} | 000388 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Contrast enhanced magnetic resonance angiogram demonstrating the arteries and veins of the neck. The entire arterial structures, from the aortic arch to the Circle of Willis, are demonstrated.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_101-PMC1796545-6-1749-7922-2-1-13.jpg"
} | 000389 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "36-year old woman, s/p motor vehicle collision. On admission, an angiogram demonstrated a pseudoaneurysm of the thoracic aorta, as well as a grade 3 (pseudoaneurysm) of her left internal carotid artery. Her aorta was repaired immediately; on follow-up angiography of her carotid injury, her pseudoaneurysm had progressed and there was significant narrowing of the adjacent internal carotid artery. Digital subtraction angiogram of the left internal carotid artery, 7-days following initial injury. There is a pseudoaneurysm (arrow) of the proximal internal carotid artery with narrowing of the adjacent artery. A second, smaller pseudoaneurysm (arrowhead) is noted in the more distal artery.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_101-PMC1796545-8-1749-7922-2-1-7.jpg"
} | 000390 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "25-year old woman involved in a rollover motor vehicle collision. On admission to the hospital, a screening four-vessel angiogram revealed a pseudoaneurysm of the left vertebral artery at the level of the C1–C2 disc space. Follow-up angiography performed 7 days later revealed enlargement of the pseudoaneurysm and concomitant narrowing of the vertebral artery. Due to the tortuosity of the vertebral artery, stent placement was not deemed a viable option and the vertebral artery was embolized. Post-embolization anteroposterior digital subtraction angiogram, right vertebral artery. There is normal filling of the basilar artery, and reflux of contrast into the distal left vertebral artery which fills the left posterior inferior cerebellar artery (arrow). Images courtesy of Guido Scatorchia, MD.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_101-PMC1796545-9-1749-7922-2-1-12.jpg"
} | 000391 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Immunohistochemistry of CD34 in angiosarcoma (streptavidin peroxidase method, ×400) immunoreactivity mainly localized to the cytoplasm of malignant cells.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_101-PMC1796548-0-1477-7800-4-3-4.jpg"
} | 000392 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Haematoxylin and eosin stain (×400); mesenchymal hamartoma with spindle and stellate cells in the mucoid matrix.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_101-PMC1796548-1-1477-7800-4-3-3.jpg"
} | 000393 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Haematoxylin and eosin stain (×400); typical features of hepatic angiosarcoma including sinusoidal and spindle-shape growth of the malignant endothelial cells, atrophy of liver cells and disruption of the hepatic plates.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_101-PMC1796548-2-1477-7800-4-3-2.jpg"
} | 000394 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Immunohistochemistry of Vimentin in angiosarcoma (streptavidin peroxidase method, ×400) immunoreactivity mainly localized to the cytoplasm of malignant cells.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_101-PMC1796548-3-1477-7800-4-3-5.jpg"
} | 000395 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Unenhanced spiral CT scan showed liver with rugositied surface, multinodular focuses involved the whole liver, calcified plaques and ascites.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_101-PMC1796548-4-1477-7800-4-3-1.jpg"
} | 000396 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Hyperpigmentation in stria vascularis. The time course of hyperpigmention during development was determined by laser scanning brightfield microscopy of stria vascularis whole-mounts. Top: images from Slc26a4+/- mice of various ages (P, postnatal day). Bottom: images from Slc26a4-/- mice. Note that hyperpigmentation (arrows) was observed in Slc26a4-/- mice at P33 and P84 but not at P10 or P15. No hyperpigmentation was observed in Slc26a4+/- mice. The scale bar shown in the bottom right image represents 10 μm and pertains to all images in this figure.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_101-PMC1796619-0-1741-7015-4-37-1.jpg"
} | 000397 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Macrophage invasion in stria vascularis. Macrophages were visualized by CD68 immunohistochemistry in whole mounts of stria vascularis and cryosections of the cochlear lateral wall. Top row: (a-d), CD68 staining in whole mounts of stria vascularis from P33 Slc26a4+/- and Slc26a4-/- mice. Immunostaining of CD68 (a and d) and corresponding bright field images (b and c) are shown. Second and third row: (e-p), CD68 staining in cryosections of the cochlear lateral wall from P33 and P80 Slc26a4+/- and Slc26a4-/- mice. Immunostaining of CD68 (e, h, k, and n), corresponding bright field images (f, i, l, and o) and merged images (g, j, m, and p) are shown. Note that CD68 expression is restricted to hyperpigmented areas of stria vascularis in Slc26a4-/- mice and that no expression of CD68 was observed in Slc26a4+/- mice. Scale bars represent 10 μm.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_101-PMC1796619-2-1741-7015-4-37-8.jpg"
} | 000398 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Controls for immunohistochemistry. Controls for CD68 immunohistochemistry were obtained from cryosections of the cochlea. Top: bone marrow cells congregated in cavities of the bony cochlear wall served as a positive control. Bottom: heavily pigmented cells in the connective tissue underneath vestibular dark cells (VDC) served as a negative control. Left: confocal immunohistochemistry of CD68. Right: corresponding bright field images. Scale bars represent 10 μm.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_101-PMC1796619-3-1741-7015-4-37-7.jpg"
} | 000399 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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